Latest Research

  • Article |

    The balance of DELLA and GRF4 proteins in plants ensures the co-regulation of growth with metabolism and tipping this balance towards GRF4 leads to higher efficiency of nitrogen use.

    • Shan Li
    • , Yonghang Tian
    • , Kun Wu
    • , Yafeng Ye
    • , Jianping Yu
    • , Jianqing Zhang
    • , Qian Liu
    • , Mengyun Hu
    • , Hui Li
    • , Yiping Tong
    • , Nicholas P. Harberd
    •  & Xiangdong Fu
  • Letter |

    Satellite observations and Earth system model simulations reveal that marine heatwaves have increased in recent decades and will increase further in terms of frequency, intensity, duration and spatial extent.

    • Thomas L. Frölicher
    • , Erich M. Fischer
    •  & Nicolas Gruber
  • Article |

    A cryo-electron microscopy structure of the insect Orco subunit, which forms ion channels with diverse olfactory receptors, reveals a tetrameric cation channel and sheds light on insect olfaction.

    • Joel A. Butterwick
    • , Josefina del Mármol
    • , Kelly H. Kim
    • , Martha A. Kahlson
    • , Jackson A. Rogow
    • , Thomas Walz
    •  & Vanessa Ruta
  • Article |

    CPEB4 binds the mRNA of genes known to be associated with autism and shows an isoform imbalance in individuals with autism, and an equivalent imbalance in mice induces an autism-like phenotype.

    • Alberto Parras
    • , Héctor Anta
    • , María Santos-Galindo
    • , Vivek Swarup
    • , Ainara Elorza
    • , José L. Nieto-González
    • , Sara Picó
    • , Ivó H. Hernández
    • , Juan I. Díaz-Hernández
    • , Eulàlia Belloc
    • , Annie Rodolosse
    • , Neelroop N. Parikshak
    • , Olga Peñagarikano
    • , Rafael Fernández-Chacón
    • , Manuel Irimia
    • , Pilar Navarro
    • , Daniel H. Geschwind
    • , Raúl Méndez
    •  & José J. Lucas
  • Letter |

    Chronic exposure to sulfoxaflor (a sulfoximine-based insecticide) has severe sub-lethal effects on bumblebee (Bombus terrestris) colonies; exposed colonies produced fewer workers and fewer reproductive offspring than unexposed control colonies.

    • Harry Siviter
    • , Mark J. F. Brown
    •  & Ellouise Leadbeater
  • Letter |

    The bacterial metabolite ADP-heptose activates NF-κB in host cells via alpha-kinase 1 and the TIFA–TRAF signalling pathway

    • Ping Zhou
    • , Yang She
    • , Na Dong
    • , Peng Li
    • , Huabin He
    • , Alessio Borio
    • , Qingcui Wu
    • , Shan Lu
    • , Xiaojun Ding
    • , Yong Cao
    • , Yue Xu
    • , Wenqing Gao
    • , Mengqiu Dong
    • , Jingjin Ding
    • , Da-Cheng Wang
    • , Alla Zamyatina
    •  & Feng Shao
  • Letter |

    Cross-correlation analysis of high-resolution spectra obtained as the exoplanet KELT-9b transited its host star reveals neutral and singly ionized atomic iron and singly ionized atomic titanium in the exoplanet’s atmosphere.

    • H. Jens Hoeijmakers
    • , David Ehrenreich
    • , Kevin Heng
    • , Daniel Kitzmann
    • , Simon L. Grimm
    • , Romain Allart
    • , Russell Deitrick
    • , Aurélien Wyttenbach
    • , Maria Oreshenko
    • , Lorenzo Pino
    • , Paul B. Rimmer
    • , Emilio Molinari
    •  & Luca Di Fabrizio

Latest Reviews & Analysis

  • News & Views |

    A previously unknown pathway that enables mammalian cells to recognize infection and trigger an immune response requires a kinase enzyme in the host cell to bind a sugar molecule produced by infecting bacteria.

    • John-Demian Sauer
  • News & Views |

    Manipulation of the transcription factor OsGRF4 can improve the efficiency with which some high-yielding cereal crops use nitrogen. This discovery has implications for sustainable agriculture.

    • Fanmiao Wang
    •  & Makoto Matsuoka
  • News & Views |

    Catalysts working in pairs can promote more-effective reactions than can the same catalysts used sequentially. The coupling of an enzyme with a light-activated catalyst offers great potential for organic synthesis.

    • Nicholas J. Turner
  • News & Views |

    Exposure to a sulfoximine-based pesticide has substantial adverse effects on bumblebee colonies. This finding suggests that concerns over the risks of exposing bees to insecticides should not be limited to neonicotinoids.

    • Nigel E. Raine
  • News & Views |

    Neutrinos are tiny, ghost-like particles that habitually change identity. A measurement of the rate of change in high-energy neutrinos racing through Earth provides a record-breaking test of Einstein’s special theory of relativity.

    • Matthew Mewes

News & Comment

  • Comment |

    Ecologists must understand how marine life responds to changing local conditions, rather than to overall global temperature rise, say Amanda E. Bates and 16 colleagues.

    • Amanda E. Bates
    • , Brian Helmuth
    • , Michael T. Burrows
    • , Murray I. Duncan
    • , Joaquim Garrabou
    • , Tamar Guy-Haim
    • , Fernando Lima
    • , Ana M. Queiros
    • , Rui Seabra
    • , Robert Marsh
    • , Jonathan Belmaker
    • , Nathaniel Bensoussan
    • , Yunwei Dong
    • , Antonios D. Mazaris
    • , Dan Smale
    • , Martin Wahl
    •  & Gil Rilov
  • Editorial |

    An in-depth analysis reveals the scale of differences among strains of common cell lines.

Nature Outlook

Alzheimer’s disease

Giulio Bonasera

Alzheimer’s disease

Alzheimer’s disease is the most common form of dementia. For decades, researchers have sought a treatment to no avail, and our understanding of the condition is now being questioned.

Nature events Directory