Editorials

Applied biomedical research needs more of them to be more broadly useful, reproducible and robust.

Appealing against an editor’s negative decision is likely to be more fruitful when considering the basis of the editorial assessment and offering ways forward.

A handy go-between may soon assist authors and editors.

When designing diagnostic assays intended for point-of-care use, more attention should be given to simplicity of operation.

Increasingly physiological in vitro models and techniques for measuring forces at multiple scales are enabling unanticipated findings in tissue mechanopathology.

The management of health and of disease conditions will eventually be supported by ever more integrated and less conspicuous wireless bioelectronic devices designed to continuously monitor multiple biomarkers.

Leverage curiosity, open-mindedness and the deliberate seeking of feedback.

Leveraging or improving established technology for clinical imaging to extract additional physiological information can enhance the quality of the subsequent assessments and widen the technology’s uses.

Established reasoning behind yearly changes in impact factors is mostly flawed.

The development of machine-learning systems for safer, robust and fairer outcomes should leverage fine-tuning, generalization, explainability and metrics of uncertainty.

The continuing optimization of the safety and applicability of CRISPR for ex vivo genome editing will broaden the prospects of cell therapies.

Bionic hands exemplify the challenges of developing neuroprostheses that can be embodied.

New strategies for enhancing the sensitivity and resolution of contrast in magnetic resonance imaging will broaden its applicability.

The consequences of their use will be far reaching.

At first glance, some research articles published in the journal may appear to lack substantial novelty.

Graph neural networks and transformers taking advantage of contextual information and large unannotated multimodal datasets are redefining what is possible in computational medicine.

Everyone benefits from the filters for rigour, excellence and trust that scholarly journals should provide.

Succinctly convey the study’s context, emphases, implications and limitations.

Research manuscripts and the associated scientific data generated for projects that are funded by federal agencies in the United States will need to be made publicly available immediately on publication.

Designing viral diagnostic tests for point-of-care use involves many trade-offs. Yet ease of use, low cost and accuracy shouldn’t be compromised.