Web Focus

2009

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Focus on Stem Cell Therapy
Focus on Stem Cell Therapy

The striking advances in the area of embryonic and adult stem cell biology and the enormous potential of using cells or tissues derived from such cells to treat a host of diseases have caught the imagination of the scientific community as well as the lay public. Even more exciting is the recent genetic reprogramming of terminally-differentiated adult cells into induced pluripotent stem (iPS) cells, which exhibit many characteristics that imply they may be an excellent alternative for cell-based therapies and regenerative medicine. In this web focus, we gather together studies representative of the enormous potential of stem cells for the treatment of disease.

2008

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Focus on RNAi as a Therapeutic Strategy
Focus on RNAi as a Therapeutic Strategy

Over 30 pharmaceutical and biotechnology companies have declared an interest in or have an active drug development program already underway in RNAi-based therapeutics to silence disease associated genes. This web focus collects together the latest research covering the development of RNAi based tools for drug target and gene function analysis as well as work describing the development of the technology for therapeutic applications.


2007

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Focus on Prostate Cancer and Gene Therapy
Focus on Prostate Cancer and Gene Therapy

Prostate cancer affects one in six men and is the second leading cause of cancer death among men in the United States. In some cases existing treatments for early prostate cancer fail, leading to advanced stage cancer that is merely managed and not cured. Gene therapy shows promise as a treatment strategy that can target both localized and metastasized prostate cancer. Recent clinical trials of various gene therapy strategies have illustrated the safety of these therapies and their potential as an effective treatment option in conjunction with existing cancer therapies. This web focus, presented by Molecular Therapy, highlights some important research that has advanced the field of prostate cancer gene therapy.

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