Molecular Therapy http://www.nature.com/mt/journal/vaop/ncurrent/rss.rdf Nature Publishing Group en Copyright © Nature Publishing Group Molecular Therapy 1525-0016 Copyright © Nature Publishing Group permissions@nature.com Molecular Therapy http://www.nature.com/aj/images/logos_b_o_w/mt.gif http://www.nature.com/mt/ In Vivo Biosafety Model to Assess the Risk of Adverse Events From Retroviral and Lentiviral Vectors http://dx.doi.org/10.1038/mt.2008.93 In Vivo Biosafety Model to Assess the Risk of Adverse Events From Retroviral and Lentiviral Vectors

Molecular Therapy advance online publication, May 6, 2008. doi:10.1038/mt.2008.93

Authors: Gerhard Bauer, Mo A Dao, Scott S Case, Todd Meyerrose, Louisa Wirthlin, Ping Zhou, Xiuli Wang, Phillip Herrbrich, Jesusa Arevalo, Susie Csik, Dianne C Skelton, Jon Walker, Karen Pepper, Donald B Kohn & Jan A Nolta

]]> In Vivo Biosafety Model to Assess the Risk of Adverse Events From Retroviral and Lentiviral Vectors Gerhard Bauer Mo A Dao Scott S Case Todd Meyerrose Louisa Wirthlin Ping Zhou Xiuli Wang Phillip Herrbrich Jesusa Arevalo Susie Csik Dianne C Skelton Jon Walker Karen Pepper Donald B Kohn Jan A Nolta doi:10.1038/mt.2008.93 Molecular Therapy advance online publication, May 6, 2008 May 6, 2008 Molecular Therapy May 6, 2008 aop current An Endogenous TNF-α Antagonist Induced by Splice-switching Oligonucleotides Reduces Inflammation in Hepatitis and Arthritis Mouse Models http://dx.doi.org/10.1038/mt.2008.85 An Endogenous TNF-α Antagonist Induced by Splice-switching Oligonucleotides Reduces Inflammation in Hepatitis and Arthritis Mouse Models

Molecular Therapy advance online publication, May 6, 2008. doi:10.1038/mt.2008.85

Authors: Maria A Graziewicz, Teresa K Tarrant, Brian Buckley, Jennifer Roberts, LeShara Fulton, Henrik Hansen, Henrik Ørum, Ryszard Kole & Peter Sazani

]]> An Endogenous TNF-α Antagonist Induced by Splice-switching Oligonucleotides Reduces Inflammation in Hepatitis and Arthritis Mouse Models Maria A Graziewicz Teresa K Tarrant Brian Buckley Jennifer Roberts LeShara Fulton Henrik Hansen Henrik Ørum Ryszard Kole Peter Sazani doi:10.1038/mt.2008.85 Molecular Therapy advance online publication, May 6, 2008 May 6, 2008 Molecular Therapy May 6, 2008 aop current Modification of Adenoviral Vectors With Polyethylene Glycol Modulates In Vivo Tissue Tropism and Gene Expression http://dx.doi.org/10.1038/mt.2008.86 Modification of Adenoviral Vectors With Polyethylene Glycol Modulates In Vivo Tissue Tropism and Gene Expression

Molecular Therapy advance online publication, May 6, 2008. doi:10.1038/mt.2008.86

Authors: Sean E Hofherr, Elena V Shashkova, Eric A Weaver, Reeti Khare & Michael A Barry

]]> Modification of Adenoviral Vectors With Polyethylene Glycol Modulates In Vivo Tissue Tropism and Gene Expression Sean E Hofherr Elena V Shashkova Eric A Weaver Reeti Khare Michael A Barry doi:10.1038/mt.2008.86 Molecular Therapy advance online publication, May 6, 2008 May 6, 2008 Molecular Therapy May 6, 2008 aop current Topical Application of Cream-emulsified CD86 siRNA Ameliorates Allergic Skin Disease by Targeting Cutaneous Dendritic Cells http://dx.doi.org/10.1038/mt.2008.91 Topical Application of Cream-emulsified CD86 siRNA Ameliorates Allergic Skin Disease by Targeting Cutaneous Dendritic Cells

Molecular Therapy advance online publication, May 6, 2008. doi:10.1038/mt.2008.91

Authors: Patcharee Ritprajak, Masaaki Hashiguchi & Miyuki Azuma

]]> Topical Application of Cream-emulsified CD86 siRNA Ameliorates Allergic Skin Disease by Targeting Cutaneous Dendritic Cells Patcharee Ritprajak Masaaki Hashiguchi Miyuki Azuma doi:10.1038/mt.2008.91 Molecular Therapy advance online publication, May 6, 2008 May 6, 2008 Molecular Therapy May 6, 2008 aop current Safety and Efficacy of Regional Intravenous (RI) Versus Intramuscular (IM) Delivery of rAAV1 and rAAV8 to Nonhuman Primate Skeletal Muscle http://dx.doi.org/10.1038/mt.2008.87 Safety and Efficacy of Regional Intravenous (RI) Versus Intramuscular (IM) Delivery of rAAV1 and rAAV8 to Nonhuman Primate Skeletal Muscle

Molecular Therapy advance online publication, May 6, 2008. doi:10.1038/mt.2008.87

Authors: Alice Toromanoff, Yan Chérel, Mickaël Guilbaud, Magalie Penaud-Budloo, Richard O Snyder, Mark E Haskins, Jack-Yves Deschamps, Lydie Guigand, Guillaume Podevin, Valder R Arruda, Katherine A High, Hansell H Stedman, Fabienne Rolling, Ignacio Anegon, Philippe Moullier & Caroline Le Guiner

]]> Safety and Efficacy of Regional Intravenous (RI) Versus Intramuscular (IM) Delivery of rAAV1 and rAAV8 to Nonhuman Primate Skeletal Muscle Alice Toromanoff Yan Chérel Mickaël Guilbaud Magalie Penaud-Budloo Richard O Snyder Mark E Haskins Jack-Yves Deschamps Lydie Guigand Guillaume Podevin Valder R Arruda Katherine A High Hansell H Stedman Fabienne Rolling Ignacio Anegon Philippe Moullier Caroline Le Guiner doi:10.1038/mt.2008.87 Molecular Therapy advance online publication, May 6, 2008 May 6, 2008 Molecular Therapy May 6, 2008 aop current Novel Dual Inhibitory Function Aptamer–siRNA Delivery System for HIV-1 Therapy http://dx.doi.org/10.1038/mt.2008.92 Novel Dual Inhibitory Function Aptamer–siRNA Delivery System for HIV-1 Therapy

Molecular Therapy advance online publication, May 6, 2008. doi:10.1038/mt.2008.92

Authors: Jiehua Zhou, Haitang Li, Shirley Li, John Zaia & John J Rossi

]]> Novel Dual Inhibitory Function Aptamer–siRNA Delivery System for HIV-1 Therapy Jiehua Zhou Haitang Li Shirley Li John Zaia John J Rossi doi:10.1038/mt.2008.92 Molecular Therapy advance online publication, May 6, 2008 May 6, 2008 Molecular Therapy May 6, 2008 aop current Inhibition of Respiratory Syncytial Virus Infections With Morpholino Oligomers in Cell Cultures and in Mice http://dx.doi.org/10.1038/mt.2008.81 Inhibition of Respiratory Syncytial Virus Infections With Morpholino Oligomers in Cell Cultures and in Mice

Molecular Therapy advance online publication, April 29, 2008. doi:10.1038/mt.2008.81

Authors: Shen-Hao Lai, David A Stein, Antonieta Guerrero-Plata, Sui-Ling Liao, Teodora Ivanciuc, Chao Hong, Patrick L Iversen, Antonella Casola & Roberto P Garofalo

]]> Inhibition of Respiratory Syncytial Virus Infections With Morpholino Oligomers in Cell Cultures and in Mice Shen-Hao Lai David A Stein Antonieta Guerrero-Plata Sui-Ling Liao Teodora Ivanciuc Chao Hong Patrick L Iversen Antonella Casola Roberto P Garofalo doi:10.1038/mt.2008.81 Molecular Therapy advance online publication, April 29, 2008 April 29, 2008 Molecular Therapy April 29, 2008 aop current Mannose 6-Phosphate Receptor–mediated Transport of Sulfamidase Across the Blood–brain Barrier in the Newborn Mouse http://dx.doi.org/10.1038/mt.2008.84 Mannose 6-Phosphate Receptor–mediated Transport of Sulfamidase Across the Blood–brain Barrier in the Newborn Mouse

Molecular Therapy advance online publication, April 29, 2008. doi:10.1038/mt.2008.84

Authors: Akihiko Urayama, Jeffrey H Grubb, William S Sly & William A Banks

]]> Mannose 6-Phosphate Receptor–mediated Transport of Sulfamidase Across the Blood–brain Barrier in the Newborn Mouse Akihiko Urayama Jeffrey H Grubb William S Sly William A Banks doi:10.1038/mt.2008.84 Molecular Therapy advance online publication, April 29, 2008 April 29, 2008 Molecular Therapy April 29, 2008 aop current A Critical Role for Type I IFN–dependent NK Cell Activation in Innate Immune Elimination of Adenoviral Vectors In Vivo http://dx.doi.org/10.1038/mt.2008.88 A Critical Role for Type I IFN–dependent NK Cell Activation in Innate Immune Elimination of Adenoviral Vectors In Vivo

Molecular Therapy advance online publication, April 29, 2008. doi:10.1038/mt.2008.88

Authors: Jiangao Zhu, Xiaopei Huang & Yiping Yang

]]> A Critical Role for Type I IFN–dependent NK Cell Activation in Innate Immune Elimination of Adenoviral Vectors In Vivo Jiangao Zhu Xiaopei Huang Yiping Yang doi:10.1038/mt.2008.88 Molecular Therapy advance online publication, April 29, 2008 April 29, 2008 Molecular Therapy April 29, 2008 aop current Enhancing the T-cell Stimulatory Capacity of Human Dendritic Cells by Co-electroporation With CD40L, CD70 and Constitutively Active TLR4 Encoding mRNA http://dx.doi.org/10.1038/mt.2008.77 Enhancing the T-cell Stimulatory Capacity of Human Dendritic Cells by Co-electroporation With CD40L, CD70 and Constitutively Active TLR4 Encoding mRNA

Molecular Therapy advance online publication, April 22, 2008. doi:10.1038/mt.2008.77

Authors: Aude Bonehill, Sandra Tuyaerts, An MT Van Nuffel, Carlo Heirman, Tomas J Bos, Karel Fostier, Bart Neyns & Kris Thielemans

]]> Enhancing the T-cell Stimulatory Capacity of Human Dendritic Cells by Co-electroporation With CD40L, CD70 and Constitutively Active TLR4 Encoding mRNA Aude Bonehill Sandra Tuyaerts An MT Van Nuffel Carlo Heirman Tomas J Bos Karel Fostier Bart Neyns Kris Thielemans doi:10.1038/mt.2008.77 Molecular Therapy advance online publication, April 22, 2008 April 22, 2008 Molecular Therapy April 22, 2008 aop current Expressed Anti-HBV Primary MicroRNA Shuttles Inhibit Viral Replication Efficiently In Vitro and In Vivo http://dx.doi.org/10.1038/mt.2008.82 Expressed Anti-HBV Primary MicroRNA Shuttles Inhibit Viral Replication Efficiently In Vitro and In Vivo

Molecular Therapy advance online publication, April 22, 2008. doi:10.1038/mt.2008.82

Authors: Abdullah Ely, Tanusha Naidoo, Steven Mufamadi, Carol Crowther & Patrick Arbuthnot

]]> Expressed Anti-HBV Primary MicroRNA Shuttles Inhibit Viral Replication Efficiently In Vitro and In Vivo Abdullah Ely Tanusha Naidoo Steven Mufamadi Carol Crowther Patrick Arbuthnot doi:10.1038/mt.2008.82 Molecular Therapy advance online publication, April 22, 2008 April 22, 2008 Molecular Therapy April 22, 2008 aop current Treg Depletion–enhanced IL-2 Treatment Facilitates Therapy of Established Tumors Using Systemically Delivered Oncolytic Virus http://dx.doi.org/10.1038/mt.2008.83 Treg Depletion–enhanced IL-2 Treatment Facilitates Therapy of Established Tumors Using Systemically Delivered Oncolytic Virus

Molecular Therapy advance online publication, April 22, 2008. doi:10.1038/mt.2008.83

Authors: Timothy Kottke, Feorillo Galivo, Phonphimon Wongthida, Rosa Maria Diaz, Jill Thompson, Dragan Jevremovic, Glen N Barber, Geoff Hall, John Chester, Peter Selby, Kevin Harrington, Alan Melcher & Richard G Vile

]]> Treg Depletion–enhanced IL-2 Treatment Facilitates Therapy of Established Tumors Using Systemically Delivered Oncolytic Virus Timothy Kottke Feorillo Galivo Phonphimon Wongthida Rosa Maria Diaz Jill Thompson Dragan Jevremovic Glen N Barber Geoff Hall John Chester Peter Selby Kevin Harrington Alan Melcher Richard G Vile doi:10.1038/mt.2008.83 Molecular Therapy advance online publication, April 22, 2008 April 22, 2008 Molecular Therapy April 22, 2008 aop current Therapeutic Effect of Recombinant Adenovirus Encoding Interferon-γ in a Murine Model of Progressive Pulmonary Tuberculosis http://dx.doi.org/10.1038/mt.2008.69 Therapeutic Effect of Recombinant Adenovirus Encoding Interferon-γ in a Murine Model of Progressive Pulmonary Tuberculosis

Molecular Therapy advance online publication, April 22, 2008. doi:10.1038/mt.2008.69

Authors: Dulce A Mata-Espinosa, Valentin Mendoza-Rodríguez, Diana Aguilar-León, Ricardo Rosales, Fernando López-Casillas & Rogelio Hernández-Pando

]]> Therapeutic Effect of Recombinant Adenovirus Encoding Interferon-γ in a Murine Model of Progressive Pulmonary Tuberculosis Dulce A Mata-Espinosa Valentin Mendoza-Rodríguez Diana Aguilar-León Ricardo Rosales Fernando López-Casillas Rogelio Hernández-Pando doi:10.1038/mt.2008.69 Molecular Therapy advance online publication, April 22, 2008 April 22, 2008 Molecular Therapy April 22, 2008 aop current Adult Bone Marrow–derived Cells Do Not Acquire Functional Attributes of Cardiomyocytes When Transplanted into Peri-infarct Myocardium http://dx.doi.org/10.1038/mt.2008.64 Adult Bone Marrow–derived Cells Do Not Acquire Functional Attributes of Cardiomyocytes When Transplanted into Peri-infarct Myocardium

Molecular Therapy advance online publication, April 22, 2008. doi:10.1038/mt.2008.64

Authors: John A Scherschel, Mark H Soonpaa, Edward F Srour, Loren J Field & Michael Rubart

]]> Adult Bone Marrow–derived Cells Do Not Acquire Functional Attributes of Cardiomyocytes When Transplanted into Peri-infarct Myocardium John A Scherschel Mark H Soonpaa Edward F Srour Loren J Field Michael Rubart doi:10.1038/mt.2008.64 Molecular Therapy advance online publication, April 22, 2008 April 22, 2008 Molecular Therapy April 22, 2008 aop current Regulated Insulin Delivery From Human Epidermal Cells Reverses Hyperglycemia http://dx.doi.org/10.1038/mt.2008.79 Regulated Insulin Delivery From Human Epidermal Cells Reverses Hyperglycemia

Molecular Therapy advance online publication, April 22, 2008. doi:10.1038/mt.2008.79

Authors: Jun Tian, Pedro Lei, Suzanne G Laychock & Stelios T Andreadis

]]> Regulated Insulin Delivery From Human Epidermal Cells Reverses Hyperglycemia Jun Tian Pedro Lei Suzanne G Laychock Stelios T Andreadis doi:10.1038/mt.2008.79 Molecular Therapy advance online publication, April 22, 2008 April 22, 2008 Molecular Therapy April 22, 2008 aop current Gene Delivery to the Juvenile Mouse Liver Using AAV2/8 Vectors http://dx.doi.org/10.1038/mt.2008.72 Gene Delivery to the Juvenile Mouse Liver Using AAV2/8 Vectors

Molecular Therapy advance online publication, April 15, 2008. doi:10.1038/mt.2008.72

Authors: Sharon C Cunningham, Allison P Dane, Afroditi Spinoulas & Ian E Alexander

]]> Gene Delivery to the Juvenile Mouse Liver Using AAV2/8 Vectors Sharon C Cunningham Allison P Dane Afroditi Spinoulas Ian E Alexander doi:10.1038/mt.2008.72 Molecular Therapy advance online publication, April 15, 2008 April 15, 2008 Molecular Therapy April 15, 2008 aop current Treatment of Obesity and Diabetes in Mice by Transplant of Gut Cells Engineered to Produce Leptin http://dx.doi.org/10.1038/mt.2008.62 Treatment of Obesity and Diabetes in Mice by Transplant of Gut Cells Engineered to Produce Leptin

Molecular Therapy advance online publication, April 15, 2008. doi:10.1038/mt.2008.62

Authors: Sarah N Oosman, Ada W Lam, George Harb, Suraj Unniappan, Ni T Lam, Travis Webber, Daniel Bruch, Qiu-Xia Zhang, Gregory S Korbutt & Timothy J Kieffer

]]> Treatment of Obesity and Diabetes in Mice by Transplant of Gut Cells Engineered to Produce Leptin Sarah N Oosman Ada W Lam George Harb Suraj Unniappan Ni T Lam Travis Webber Daniel Bruch Qiu-Xia Zhang Gregory S Korbutt Timothy J Kieffer doi:10.1038/mt.2008.62 Molecular Therapy advance online publication, April 15, 2008 April 15, 2008 Molecular Therapy April 15, 2008 aop current Systemic AAV6 Delivery Mediating RNA Interference Against SOD1: Neuromuscular Transduction Does Not Alter Disease Progression in fALS Mice http://dx.doi.org/10.1038/mt.2008.73 Systemic AAV6 Delivery Mediating RNA Interference Against SOD1: Neuromuscular Transduction Does Not Alter Disease Progression in fALS Mice

Molecular Therapy advance online publication, April 15, 2008. doi:10.1038/mt.2008.73

Authors: Chris Towne, Cédric Raoul, Bernard L Schneider & Patrick Aebischer

]]> Systemic AAV6 Delivery Mediating RNA Interference Against SOD1: Neuromuscular Transduction Does Not Alter Disease Progression in fALS Mice Chris Towne Cédric Raoul Bernard L Schneider Patrick Aebischer doi:10.1038/mt.2008.73 Molecular Therapy advance online publication, April 15, 2008 April 15, 2008 Molecular Therapy April 15, 2008 aop current Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection http://dx.doi.org/10.1038/mt.2008.76 Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection

Molecular Therapy advance online publication, April 15, 2008. doi:10.1038/mt.2008.76

Authors: Carmela Zincarelli, Stephen Soltys, Giuseppe Rengo & Joseph E Rabinowitz

]]> Analysis of AAV Serotypes 1–9 Mediated Gene Expression and Tropism in Mice After Systemic Injection Carmela Zincarelli Stephen Soltys Giuseppe Rengo Joseph E Rabinowitz doi:10.1038/mt.2008.76 Molecular Therapy advance online publication, April 15, 2008 April 15, 2008 Molecular Therapy April 15, 2008 aop current HSP70 and Constitutively Active HSF1 Mediate Protection Against CDCrel-1-mediated Toxicity http://dx.doi.org/10.1038/mt.2008.68 HSP70 and Constitutively Active HSF1 Mediate Protection Against CDCrel-1-mediated Toxicity

Molecular Therapy advance online publication, April 8, 2008. doi:10.1038/mt.2008.68

Authors: Alisha E Jung, Helen L Fitzsimons, Ross J Bland, Matthew J During & Deborah Young

]]> HSP70 and Constitutively Active HSF1 Mediate Protection Against CDCrel-1-mediated Toxicity Alisha E Jung Helen L Fitzsimons Ross J Bland Matthew J During Deborah Young doi:10.1038/mt.2008.68 Molecular Therapy advance online publication, April 8, 2008 April 8, 2008 Molecular Therapy April 8, 2008 aop current Novel Cancer Antiangiotherapy Using the VEGF Promoter-targeted Artificial Zinc-finger Protein and Oncolytic Adenovirus http://dx.doi.org/10.1038/mt.2008.63 Novel Cancer Antiangiotherapy Using the VEGF Promoter-targeted Artificial Zinc-finger Protein and Oncolytic Adenovirus

Molecular Therapy advance online publication, April 8, 2008. doi:10.1038/mt.2008.63

Authors: Yoon-A Kang, Hyun-Chul Shin, Ji Young Yoo, Joo-Hang Kim, Jin-Soo Kim & Chae-Ok Yun

]]> Novel Cancer Antiangiotherapy Using the VEGF Promoter-targeted Artificial Zinc-finger Protein and Oncolytic Adenovirus Yoon-A Kang Hyun-Chul Shin Ji Young Yoo Joo-Hang Kim Jin-Soo Kim Chae-Ok Yun doi:10.1038/mt.2008.63 Molecular Therapy advance online publication, April 8, 2008 April 8, 2008 Molecular Therapy April 8, 2008 aop current Rapid Lentiviral Transduction Preserves the Engraftment Potential of Fanca–/– Hematopoietic Stem Cells http://dx.doi.org/10.1038/mt.2008.67 Rapid Lentiviral Transduction Preserves the Engraftment Potential of Fanca–/– Hematopoietic Stem Cells

Molecular Therapy advance online publication, April 8, 2008. doi:10.1038/mt.2008.67

Authors: Lars UW Müller, Michael D Milsom, Mi-Ok Kim, Axel Schambach, Todd Schuesler & David A Williams

]]> Rapid Lentiviral Transduction Preserves the Engraftment Potential of Fanca–/– Hematopoietic Stem Cells Lars UW Müller Michael D Milsom Mi-Ok Kim Axel Schambach Todd Schuesler David A Williams doi:10.1038/mt.2008.67 Molecular Therapy advance online publication, April 8, 2008 April 8, 2008 Molecular Therapy April 8, 2008 aop current Computer-assisted Hydrodynamic Gene Delivery http://dx.doi.org/10.1038/mt.2008.66 Computer-assisted Hydrodynamic Gene Delivery

Molecular Therapy advance online publication, April 8, 2008. doi:10.1038/mt.2008.66

Authors: Takeshi Suda, Kieko Suda & Dexi Liu

]]> Computer-assisted Hydrodynamic Gene Delivery Takeshi Suda Kieko Suda Dexi Liu doi:10.1038/mt.2008.66 Molecular Therapy advance online publication, April 8, 2008 April 8, 2008 Molecular Therapy April 8, 2008 aop current Delivery of AAV-IGF-1 to the CNS Extends Survival in ALS Mice Through Modification of Aberrant Glial Cell Activity http://dx.doi.org/10.1038/mt.2008.60 Delivery of AAV-IGF-1 to the CNS Extends Survival in ALS Mice Through Modification of Aberrant Glial Cell Activity

Molecular Therapy advance online publication, April 1, 2008. doi:10.1038/mt.2008.60

Authors: James C Dodge, Amanda M Haidet, Wendy Yang, Marco A Passini, Mark Hester, Jennifer Clarke, Eric M Roskelley, Christopher M Treleaven, Liza Rizo, Heather Martin, Soo H Kim, Rita Kaspar, Tatyana V Taksir, Denise A Griffiths, Seng H Cheng, Lamya S Shihabuddin & Brian K Kaspar

]]> Delivery of AAV-IGF-1 to the CNS Extends Survival in ALS Mice Through Modification of Aberrant Glial Cell Activity James C Dodge Amanda M Haidet Wendy Yang Marco A Passini Mark Hester Jennifer Clarke Eric M Roskelley Christopher M Treleaven Liza Rizo Heather Martin Soo H Kim Rita Kaspar Tatyana V Taksir Denise A Griffiths Seng H Cheng Lamya S Shihabuddin Brian K Kaspar doi:10.1038/mt.2008.60 Molecular Therapy advance online publication, April 1, 2008 April 1, 2008 Molecular Therapy April 1, 2008 aop current Trichostatin A and Oncolytic HSV Combination Therapy Shows Enhanced Antitumoral and Antiangiogenic Effects http://dx.doi.org/10.1038/mt.2008.58 Trichostatin A and Oncolytic HSV Combination Therapy Shows Enhanced Antitumoral and Antiangiogenic Effects

Molecular Therapy advance online publication, April 1, 2008. doi:10.1038/mt.2008.58

Authors: Ta-Chiang Liu, Pedro Castelo-Branco, Samuel D Rabkin & Robert L Martuza

]]> Trichostatin A and Oncolytic HSV Combination Therapy Shows Enhanced Antitumoral and Antiangiogenic Effects Ta-Chiang Liu Pedro Castelo-Branco Samuel D Rabkin Robert L Martuza doi:10.1038/mt.2008.58 Molecular Therapy advance online publication, April 1, 2008 April 1, 2008 Molecular Therapy April 1, 2008 aop current Use of A U16 snoRNA-containing Ribozyme Library to Identify Ribozyme Targets in HIV-1 http://dx.doi.org/10.1038/mt.2008.54 Use of A U16 snoRNA-containing Ribozyme Library to Identify Ribozyme Targets in HIV-1

Molecular Therapy advance online publication, April 1, 2008. doi:10.1038/mt.2008.54

Authors: Hoshang J Unwalla, Haitang Li, Shi-Yang Li, Danny Abad & John J Rossi

]]> Use of A U16 snoRNA-containing Ribozyme Library to Identify Ribozyme Targets in HIV-1 Hoshang J Unwalla Haitang Li Shi-Yang Li Danny Abad John J Rossi doi:10.1038/mt.2008.54 Molecular Therapy advance online publication, April 1, 2008 April 1, 2008 Molecular Therapy April 1, 2008 aop current Effect of Late-stage Therapy on Disease Progression in AAV-mediated Rescue of Photoreceptor Cells in the Retinoschisin-deficient Mouse http://dx.doi.org/10.1038/mt.2008.57 Effect of Late-stage Therapy on Disease Progression in AAV-mediated Rescue of Photoreceptor Cells in the Retinoschisin-deficient Mouse

Molecular Therapy advance online publication, March 25, 2008. doi:10.1038/mt.2008.57

Authors: Andreas Janssen, Seok H Min, Laurie L Molday, Naoyuki Tanimoto, Mathias W Seeliger, William W Hauswirth, Robert S Molday & Bernhard HF Weber

]]> Effect of Late-stage Therapy on Disease Progression in AAV-mediated Rescue of Photoreceptor Cells in the Retinoschisin-deficient Mouse Andreas Janssen Seok H Min Laurie L Molday Naoyuki Tanimoto Mathias W Seeliger William W Hauswirth Robert S Molday Bernhard HF Weber doi:10.1038/mt.2008.57 Molecular Therapy advance online publication, March 25, 2008 March 25, 2008 Molecular Therapy March 25, 2008 aop current Lentiviral Vector–mediated SERCA2 Gene Transfer Protects Against Heart Failure and Left Ventricular Remodeling After Myocardial Infarction in Rats http://dx.doi.org/10.1038/mt.2008.61 Lentiviral Vector–mediated SERCA2 Gene Transfer Protects Against Heart Failure and Left Ventricular Remodeling After Myocardial Infarction in Rats

Molecular Therapy advance online publication, March 25, 2008. doi:10.1038/mt.2008.61

Authors: Kazuo Niwano, Masashi Arai, Norimichi Koitabashi, Atai Watanabe, Yasuhiro Ikeda, Hiroyuki Miyoshi & Masahiko Kurabayashi

]]> Lentiviral Vector–mediated SERCA2 Gene Transfer Protects Against Heart Failure and Left Ventricular Remodeling After Myocardial Infarction in Rats Kazuo Niwano Masashi Arai Norimichi Koitabashi Atai Watanabe Yasuhiro Ikeda Hiroyuki Miyoshi Masahiko Kurabayashi doi:10.1038/mt.2008.61 Molecular Therapy advance online publication, March 25, 2008 March 25, 2008 Molecular Therapy March 25, 2008 aop current Heterologous Boosting of Recombinant Adenoviral Prime Immunization With a Novel Vesicular Stomatitis Virus–vectored Tuberculosis Vaccine http://dx.doi.org/10.1038/mt.2008.59 Heterologous Boosting of Recombinant Adenoviral Prime Immunization With a Novel Vesicular Stomatitis Virus–vectored Tuberculosis Vaccine

Molecular Therapy advance online publication, March 25, 2008. doi:10.1038/mt.2008.59

Authors: Elizabeth K Roediger, Kapilan Kugathasan, XiZhong Zhang, Brian D Lichty & Zhou Xing

]]> Heterologous Boosting of Recombinant Adenoviral Prime Immunization With a Novel Vesicular Stomatitis Virus–vectored Tuberculosis Vaccine Elizabeth K Roediger Kapilan Kugathasan XiZhong Zhang Brian D Lichty Zhou Xing doi:10.1038/mt.2008.59 Molecular Therapy advance online publication, March 25, 2008 March 25, 2008 Molecular Therapy March 25, 2008 aop current Extended Transgene Expression From a Nonintegrating Adenoviral Vector Containing Retroviral Elements http://dx.doi.org/10.1038/mt.2008.56 Extended Transgene Expression From a Nonintegrating Adenoviral Vector Containing Retroviral Elements

Molecular Therapy advance online publication, March 25, 2008. doi:10.1038/mt.2008.56

Authors: Changyu Zheng, Joseph M Vitolo, Weitian Zhang, Fumi Mineshiba, John A Chiorini & Bruce J Baum

]]> Extended Transgene Expression From a Nonintegrating Adenoviral Vector Containing Retroviral Elements Changyu Zheng Joseph M Vitolo Weitian Zhang Fumi Mineshiba John A Chiorini Bruce J Baum doi:10.1038/mt.2008.56 Molecular Therapy advance online publication, March 25, 2008 March 25, 2008 Molecular Therapy March 25, 2008 aop current Intraventricular Enzyme Replacement Improves Disease Phenotypes in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis http://dx.doi.org/10.1038/sj.mt.6300415 Intraventricular Enzyme Replacement Improves Disease Phenotypes in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis

Molecular Therapy advance online publication, February 12, 2008. doi:10.1038/sj.mt.6300415

Authors: Michael Chang, Jonathan D Cooper, David E Sleat, Seng H Cheng, James C Dodge, Marco A Passini, Peter Lobel & Beverly L Davidson

]]> Intraventricular Enzyme Replacement Improves Disease Phenotypes in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis Michael Chang Jonathan D Cooper David E Sleat Seng H Cheng James C Dodge Marco A Passini Peter Lobel Beverly L Davidson doi:10.1038/sj.mt.6300415 Molecular Therapy advance online publication, February 12, 2008 February 12, 2008 Molecular Therapy February 12, 2008 aop current Gene Therapy of βc-Deficient Pulmonary Alveolar Proteinosis (βc-PAP): Studies in a Murine in vivo Model http://dx.doi.org/10.1038/mt.2008.7 Gene Therapy of βc-Deficient Pulmonary Alveolar Proteinosis (βc-PAP): Studies in a Murine in vivo Model

Molecular Therapy advance online publication, February 12, 2008. doi:10.1038/mt.2008.7

Authors: Veronika Kleff, Ursula R Sorg, Carsten Bury, Takuji Suzuki, Ina Rattmann, Moran Jerabek-Willemsen, Christopher Poremba, Michael Flasshove, Bertram Opalka, Bruce Trapnell, Uta Dirksen & Thomas Moritz

]]> Gene Therapy of βc-Deficient Pulmonary Alveolar Proteinosis (βc-PAP): Studies in a Murine in vivo Model Veronika Kleff Ursula R Sorg Carsten Bury Takuji Suzuki Ina Rattmann Moran Jerabek-Willemsen Christopher Poremba Michael Flasshove Bertram Opalka Bruce Trapnell Uta Dirksen Thomas Moritz doi:10.1038/mt.2008.7 Molecular Therapy advance online publication, February 12, 2008 February 12, 2008 Molecular Therapy February 12, 2008 aop current Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol http://dx.doi.org/10.1038/sj.mt.6300420 Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol

Molecular Therapy advance online publication, February 12, 2008. doi:10.1038/sj.mt.6300420

Authors: Kazutaka Nishina, Toshinori Unno, Yoshitaka Uno, Takayuki Kubodera, Tadashi Kanouchi, Hidehiro Mizusawa & Takanori Yokota

]]> Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol Kazutaka Nishina Toshinori Unno Yoshitaka Uno Takayuki Kubodera Tadashi Kanouchi Hidehiro Mizusawa Takanori Yokota doi:10.1038/sj.mt.6300420 Molecular Therapy advance online publication, February 12, 2008 February 12, 2008 Molecular Therapy February 12, 2008 aop current Bovine Adenoviral Vector–based H5N1 Influenza Vaccine Overcomes Exceptionally High Levels of Pre-existing Immunity Against Human Adenovirus http://dx.doi.org/10.1038/mt.2008.11 Bovine Adenoviral Vector–based H5N1 Influenza Vaccine Overcomes Exceptionally High Levels of Pre-existing Immunity Against Human Adenovirus

Molecular Therapy advance online publication, February 12, 2008. doi:10.1038/mt.2008.11

Authors: Neetu Singh, Aseem Pandey, Lakshmi Jayashankar & Suresh K Mittal

]]> Bovine Adenoviral Vector–based H5N1 Influenza Vaccine Overcomes Exceptionally High Levels of Pre-existing Immunity Against Human Adenovirus Neetu Singh Aseem Pandey Lakshmi Jayashankar Suresh K Mittal doi:10.1038/mt.2008.11 Molecular Therapy advance online publication, February 12, 2008 February 12, 2008 Molecular Therapy February 12, 2008 aop current Ranibizumab for Macular Edema Due to Retinal Vein Occlusions; Implication of VEGF as a Critical Stimulator http://dx.doi.org/10.1038/sj.mt.6300416 Ranibizumab for Macular Edema Due to Retinal Vein Occlusions; Implication of VEGF as a Critical Stimulator

Molecular Therapy advance online publication, February 5, 2008. doi:10.1038/sj.mt.6300416

Authors: Peter A Campochiaro, Gulnar Hafiz, Syed Mahmood Shah, Quan Dong Nguyen, Howard Ying, Diana V Do, Edward Quinlan, Ingrid Zimmer-Galler, Julia A Haller, Sharon D Solomon, Jennifer U Sung, Yasmin Hadi, Kashif A Janjua, Nida Jawed, David F Choy & Joseph R Arron

]]> Ranibizumab for Macular Edema Due to Retinal Vein Occlusions; Implication of VEGF as a Critical Stimulator Peter A Campochiaro Gulnar Hafiz Syed Mahmood Shah Quan Dong Nguyen Howard Ying Diana V Do Edward Quinlan Ingrid Zimmer-Galler Julia A Haller Sharon D Solomon Jennifer U Sung Yasmin Hadi Kashif A Janjua Nida Jawed David F Choy Joseph R Arron doi:10.1038/sj.mt.6300416 Molecular Therapy advance online publication, February 5, 2008 February 5, 2008 Molecular Therapy February 5, 2008 aop current A Tumor-selective Biotherapy With Prolonged Impact on Established Metastases Based on Cytokine Gene-engineered MSCs http://dx.doi.org/10.1038/sj.mt.6300409 A Tumor-selective Biotherapy With Prolonged Impact on Established Metastases Based on Cytokine Gene-engineered MSCs

Molecular Therapy advance online publication, February 5, 2008. doi:10.1038/sj.mt.6300409

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Molecular Therapy advance online publication, February 5, 2008. doi:10.1038/sj.mt.6300407

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]]> Phase I Clinical Trial of Autologous Ascites-derived Exosomes Combined With GM-CSF for Colorectal Cancer Shengming Dai Dong Wei Zhen Wu Xiangyang Zhou Xiaomou Wei Haixin Huang Guisheng Li doi:10.1038/sj.mt.6300407 Molecular Therapy advance online publication, February 5, 2008 February 5, 2008 Molecular Therapy February 5, 2008 aop current TAT-mediated Delivery of LAD Restores Pyruvate Dehydrogenase Complex Activity in the Mitochondria of Patients with LAD Deficiency http://dx.doi.org/10.1038/sj.mt.6300410 TAT-mediated Delivery of LAD Restores Pyruvate Dehydrogenase Complex Activity in the Mitochondria of Patients with LAD Deficiency

Molecular Therapy advance online publication, February 5, 2008. doi:10.1038/sj.mt.6300410

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]]> TAT-mediated Delivery of LAD Restores Pyruvate Dehydrogenase Complex Activity in the Mitochondria of Patients with LAD Deficiency Matan Rapoport Ann Saada Orly Elpeleg Haya Lorberboum-Galski doi:10.1038/sj.mt.6300410 Molecular Therapy advance online publication, February 5, 2008 February 5, 2008 Molecular Therapy February 5, 2008 aop current