Molecular Therapy http://www.nature.com/mt/journal/vaop/ncurrent/rss.rdf Nature Publishing Group en Copyright © Nature Publishing Group Molecular Therapy 1525-0016 Copyright © Nature Publishing Group permissions@nature.com Molecular Therapy http://www.nature.com/aj/images/logos_b_o_w/mt.gif http://www.nature.com/mt/ Sonic Hedgehog Expands Diaphyseal Trabecular Bone Altering Bone Marrow Niche and Lymphocyte Compartment http://dx.doi.org/10.1038/mt.2009.102 Sonic Hedgehog Expands Diaphyseal Trabecular Bone Altering Bone Marrow Niche and Lymphocyte Compartment

Molecular Therapy advance online publication, May 12, 2009. doi:10.1038/mt.2009.102

Authors: Maija Kiuru, Chisa Hidaka, Ralf-Harto Hubner, Jason Solomon, Anja Krause, Philip L Leopold & Ronald G Crystal

]]> Sonic Hedgehog Expands Diaphyseal Trabecular Bone Altering Bone Marrow Niche and Lymphocyte Compartment Maija Kiuru Chisa Hidaka Ralf-Harto Hubner Jason Solomon Anja Krause Philip L Leopold Ronald G Crystal doi:10.1038/mt.2009.102 Molecular Therapy advance online publication, May 12, 2009 2009-05-12 Molecular Therapy May 12, 2009 10.1038/mt.2009.102 http://dx.doi.org/10.1038/mt.2009.102 aop current Suppression of Cancer Growth by Nonviral Gene Therapy Based on a Novel Reactive Oxygen Species-responsive Promoter http://dx.doi.org/10.1038/mt.2009.103 Suppression of Cancer Growth by Nonviral Gene Therapy Based on a Novel Reactive Oxygen Species-responsive Promoter

Molecular Therapy advance online publication, May 12, 2009. doi:10.1038/mt.2009.103

Authors: Lucía L Policastro, Irene L Ibañez, Hebe A Durán, Gastón Soria, Vanesa Gottifredi & Osvaldo L Podhajcer

]]> Suppression of Cancer Growth by Nonviral Gene Therapy Based on a Novel Reactive Oxygen Species-responsive Promoter Lucía L Policastro Irene L Ibañez Hebe A Durán Gastón Soria Vanesa Gottifredi Osvaldo L Podhajcer doi:10.1038/mt.2009.103 Molecular Therapy advance online publication, May 12, 2009 2009-05-12 Molecular Therapy May 12, 2009 10.1038/mt.2009.103 http://dx.doi.org/10.1038/mt.2009.103 aop current Attraction and Activation of Dendritic Cells at the Site of Tumor Elicits Potent Antitumor Immunity http://dx.doi.org/10.1038/mt.2009.111 Attraction and Activation of Dendritic Cells at the Site of Tumor Elicits Potent Antitumor Immunity

Molecular Therapy advance online publication, June 16, 2009. doi:10.1038/mt.2009.111

Authors: Natalia Lapteva, Melissa Aldrich, Lisa Rollins, Wenhong Ren, Tatiana Goltsova, Si-Yi Chen & Xue F Huang

]]> Attraction and Activation of Dendritic Cells at the Site of Tumor Elicits Potent Antitumor Immunity Natalia Lapteva Melissa Aldrich Lisa Rollins Wenhong Ren Tatiana Goltsova Si-Yi Chen Xue F Huang doi:10.1038/mt.2009.111 Molecular Therapy advance online publication, June 16, 2009 2009-06-16 Molecular Therapy June 16, 2009 10.1038/mt.2009.111 http://dx.doi.org/10.1038/mt.2009.111 aop current AAV-mediated Tyrosinase Gene Transfer Restores Melanogenesis and Retinal Function in a Model of Oculo-cutaneous Albinism Type I (OCA1) http://dx.doi.org/10.1038/mt.2009.112 AAV-mediated Tyrosinase Gene Transfer Restores Melanogenesis and Retinal Function in a Model of Oculo-cutaneous Albinism Type I (OCA1)

Molecular Therapy advance online publication, May 12, 2009. doi:10.1038/mt.2009.112

Authors: Annagiusi Gargiulo, Ciro Bonetti, Sandro Montefusco, Simona Neglia, Umberto Di Vicino, Elena Marrocco, Michele Della Corte, Luciano Domenici, Alberto Auricchio & Enrico M Surace

]]> AAV-mediated Tyrosinase Gene Transfer Restores Melanogenesis and Retinal Function in a Model of Oculo-cutaneous Albinism Type I (OCA1) Annagiusi Gargiulo Ciro Bonetti Sandro Montefusco Simona Neglia Umberto Di Vicino Elena Marrocco Michele Della Corte Luciano Domenici Alberto Auricchio Enrico M Surace doi:10.1038/mt.2009.112 Molecular Therapy advance online publication, May 12, 2009 2009-05-12 Molecular Therapy May 12, 2009 10.1038/mt.2009.112 http://dx.doi.org/10.1038/mt.2009.112 aop current Abrogation of Microsatellite-instable Tumors Using a Highly Selective Suicide Gene/Prodrug Combination http://dx.doi.org/10.1038/mt.2009.114 Abrogation of Microsatellite-instable Tumors Using a Highly Selective Suicide Gene/Prodrug Combination

Molecular Therapy advance online publication, May 26, 2009. doi:10.1038/mt.2009.114

Authors: Cristina Ferrás, Joachim AF Oude Vrielink, Johan WA Verspuy, Hein te Riele, Anastasia Tsaalbi-Shtylik & Niels de Wind

]]> Abrogation of Microsatellite-instable Tumors Using a Highly Selective Suicide Gene/Prodrug Combination Cristina Ferrás Joachim AF Oude Vrielink Johan WA Verspuy Hein te Riele Anastasia Tsaalbi-Shtylik Niels de Wind doi:10.1038/mt.2009.114 Molecular Therapy advance online publication, May 26, 2009 2009-05-26 Molecular Therapy May 26, 2009 10.1038/mt.2009.114 http://dx.doi.org/10.1038/mt.2009.114 aop current Expression of Neprilysin in Skeletal Muscle Reduces Amyloid Burden in a Transgenic Mouse Model of Alzheimer Disease http://dx.doi.org/10.1038/mt.2009.115 Expression of Neprilysin in Skeletal Muscle Reduces Amyloid Burden in a Transgenic Mouse Model of Alzheimer Disease

Molecular Therapy advance online publication, May 26, 2009. doi:10.1038/mt.2009.115

Authors: Yinxing Liu, Christa Studzinski, Tina Beckett, Hanjun Guan, Matthew A Hersh, M Paul Murphy, Ronald Klein & Louis B Hersh

]]> Expression of Neprilysin in Skeletal Muscle Reduces Amyloid Burden in a Transgenic Mouse Model of Alzheimer Disease Yinxing Liu Christa Studzinski Tina Beckett Hanjun Guan Matthew A Hersh M Paul Murphy Ronald Klein Louis B Hersh doi:10.1038/mt.2009.115 Molecular Therapy advance online publication, May 26, 2009 2009-05-26 Molecular Therapy May 26, 2009 10.1038/mt.2009.115 http://dx.doi.org/10.1038/mt.2009.115 aop current Evaluation of Vascular Delivery Methodologies to Enhance rAAV6-mediated Gene Transfer to Canine Striated Musculature http://dx.doi.org/10.1038/mt.2009.116 Evaluation of Vascular Delivery Methodologies to Enhance rAAV6-mediated Gene Transfer to Canine Striated Musculature

Molecular Therapy advance online publication, May 26, 2009. doi:10.1038/mt.2009.116

Authors: Paul Gregorevic, Brian R Schultz, James M Allen, Jeffrey B Halldorson, Michael J Blankinship, Norman A Meznarich, Christian S Kuhr, Caitlin Doremus, Eric Finn, Denny Liggitt & Jeffrey S Chamberlain

]]> Evaluation of Vascular Delivery Methodologies to Enhance rAAV6-mediated Gene Transfer to Canine Striated Musculature Paul Gregorevic Brian R Schultz James M Allen Jeffrey B Halldorson Michael J Blankinship Norman A Meznarich Christian S Kuhr Caitlin Doremus Eric Finn Denny Liggitt Jeffrey S Chamberlain doi:10.1038/mt.2009.116 Molecular Therapy advance online publication, May 26, 2009 2009-05-26 Molecular Therapy May 26, 2009 10.1038/mt.2009.116 http://dx.doi.org/10.1038/mt.2009.116 aop current Treatment With Cyclooxygenase-2 Inhibitors Enables Repeated Administration of Vaccinia Virus for Control of Ovarian Cancer http://dx.doi.org/10.1038/mt.2009.118 Treatment With Cyclooxygenase-2 Inhibitors Enables Repeated Administration of Vaccinia Virus for Control of Ovarian Cancer

Molecular Therapy advance online publication, May 26, 2009. doi:10.1038/mt.2009.118

Authors: Chih-Long Chang, Barbara Ma, Xiaowu Pang, T-C Wu & Chien-Fu Hung

]]> Treatment With Cyclooxygenase-2 Inhibitors Enables Repeated Administration of Vaccinia Virus for Control of Ovarian Cancer Chih-Long Chang Barbara Ma Xiaowu Pang T-C Wu Chien-Fu Hung doi:10.1038/mt.2009.118 Molecular Therapy advance online publication, May 26, 2009 2009-05-26 Molecular Therapy May 26, 2009 10.1038/mt.2009.118 http://dx.doi.org/10.1038/mt.2009.118 aop current Enhanced Percolation and Gene Expression in Tumor Hypoxia by PEGylated Polyplex Micelles http://dx.doi.org/10.1038/mt.2009.119 Enhanced Percolation and Gene Expression in Tumor Hypoxia by PEGylated Polyplex Micelles

Molecular Therapy advance online publication, May 26, 2009. doi:10.1038/mt.2009.119

Authors: Muri Han, Makoto Oba, Nobuhiro Nishiyama, Mitsunobu R Kano, Shinae Kizaka-Kondoh & Kazunori Kataoka

]]> Enhanced Percolation and Gene Expression in Tumor Hypoxia by PEGylated Polyplex Micelles Muri Han Makoto Oba Nobuhiro Nishiyama Mitsunobu R Kano Shinae Kizaka-Kondoh Kazunori Kataoka doi:10.1038/mt.2009.119 Molecular Therapy advance online publication, May 26, 2009 2009-05-26 Molecular Therapy May 26, 2009 10.1038/mt.2009.119 http://dx.doi.org/10.1038/mt.2009.119 aop current Optimization of Skin Electroporation in Mice to Increase Tolerability of DNA Vaccine Delivery to Patients http://dx.doi.org/10.1038/mt.2009.120 Optimization of Skin Electroporation in Mice to Increase Tolerability of DNA Vaccine Delivery to Patients

Molecular Therapy advance online publication, June 16, 2009. doi:10.1038/mt.2009.120

Authors: Anna-Karin Roos, Fredrik Eriksson, Derin C Walters, Pavel Pisa & Alan D King

]]> Optimization of Skin Electroporation in Mice to Increase Tolerability of DNA Vaccine Delivery to Patients Anna-Karin Roos Fredrik Eriksson Derin C Walters Pavel Pisa Alan D King doi:10.1038/mt.2009.120 Molecular Therapy advance online publication, June 16, 2009 2009-06-16 Molecular Therapy June 16, 2009 10.1038/mt.2009.120 http://dx.doi.org/10.1038/mt.2009.120 aop current Fluid Phase Endocytosis Contributes to Transfection of DNA by PEI-25 http://dx.doi.org/10.1038/mt.2009.121 Fluid Phase Endocytosis Contributes to Transfection of DNA by PEI-25

Molecular Therapy advance online publication, June 16, 2009. doi:10.1038/mt.2009.121

Authors: Hansjörg Hufnagel, Parvez Hakim, Aline Lima & Florian Hollfelder

]]> Fluid Phase Endocytosis Contributes to Transfection of DNA by PEI-25 Hansjörg Hufnagel Parvez Hakim Aline Lima Florian Hollfelder doi:10.1038/mt.2009.121 Molecular Therapy advance online publication, June 16, 2009 2009-06-16 Molecular Therapy June 16, 2009 10.1038/mt.2009.121 http://dx.doi.org/10.1038/mt.2009.121 aop current Integration-deficient Lentiviral Vectors: A Slow Coming of Age http://dx.doi.org/10.1038/mt.2009.122 Integration-deficient Lentiviral Vectors: A Slow Coming of Age

Molecular Therapy advance online publication, June 2, 2009. doi:10.1038/mt.2009.122

Authors: Klaus Wanisch & Rafael J Yáñez-Muñoz

]]> Integration-deficient Lentiviral Vectors: A Slow Coming of Age Klaus Wanisch Rafael J Yáñez-Muñoz doi:10.1038/mt.2009.122 Molecular Therapy advance online publication, June 2, 2009 2009-06-02 Molecular Therapy June 2, 2009 10.1038/mt.2009.122 http://dx.doi.org/10.1038/mt.2009.122 aop current Allele-specific RNAi Mitigates Phenotypic Progression in a Transgenic Model of Alzheimer's Disease http://dx.doi.org/10.1038/mt.2009.123 Allele-specific RNAi Mitigates Phenotypic Progression in a Transgenic Model of Alzheimer's Disease

Molecular Therapy advance online publication, June 16, 2009. doi:10.1038/mt.2009.123

Authors: Edgardo Rodríguez-Lebrón, Cynthia M Gouvion, Steven A Moore, Beverly L Davidson & Henry L Paulson

]]> Allele-specific RNAi Mitigates Phenotypic Progression in a Transgenic Model of Alzheimer's Disease Edgardo Rodríguez-Lebrón Cynthia M Gouvion Steven A Moore Beverly L Davidson Henry L Paulson doi:10.1038/mt.2009.123 Molecular Therapy advance online publication, June 16, 2009 2009-06-16 Molecular Therapy June 16, 2009 10.1038/mt.2009.123 http://dx.doi.org/10.1038/mt.2009.123 aop current High-efficiency Transient Transduction of Human Embryonic Stem Cell–derived Neurons With Baculoviral Vectors http://dx.doi.org/10.1038/mt.2009.124 High-efficiency Transient Transduction of Human Embryonic Stem Cell–derived Neurons With Baculoviral Vectors

Molecular Therapy advance online publication, June 16, 2009. doi:10.1038/mt.2009.124

Authors: Jieming Zeng, Juan Du, Jiakai Lin, Xiao Ying Bak, Chunxiao Wu & Shu Wang

]]> High-efficiency Transient Transduction of Human Embryonic Stem Cell–derived Neurons With Baculoviral Vectors Jieming Zeng Juan Du Jiakai Lin Xiao Ying Bak Chunxiao Wu Shu Wang doi:10.1038/mt.2009.124 Molecular Therapy advance online publication, June 16, 2009 2009-06-16 Molecular Therapy June 16, 2009 10.1038/mt.2009.124 http://dx.doi.org/10.1038/mt.2009.124 aop current Phase I/II and Phase II Studies of Targeted Gene Delivery In Vivo: Intravenous Rexin-G for Chemotherapy-resistant Sarcoma and Osteosarcoma http://dx.doi.org/10.1038/mt.2009.126 Phase I/II and Phase II Studies of Targeted Gene Delivery In Vivo: Intravenous Rexin-G for Chemotherapy-resistant Sarcoma and Osteosarcoma

Molecular Therapy advance online publication, June 16, 2009. doi:10.1038/mt.2009.126

Authors: Sant P Chawla, Victoria S Chua, Lita Fernandez, Doris Quon, Andreh Saralou, William C Blackwelder, Frederick L Hall & Erlinda M Gordon

]]> Phase I/II and Phase II Studies of Targeted Gene Delivery In Vivo: Intravenous Rexin-G for Chemotherapy-resistant Sarcoma and Osteosarcoma Sant P Chawla Victoria S Chua Lita Fernandez Doris Quon Andreh Saralou William C Blackwelder Frederick L Hall Erlinda M Gordon doi:10.1038/mt.2009.126 Molecular Therapy advance online publication, June 16, 2009 2009-06-16 Molecular Therapy June 16, 2009 10.1038/mt.2009.126 http://dx.doi.org/10.1038/mt.2009.126 aop current Identification of Protein Cofactors Necessary for Sequence-specific Plasmid DNA Nuclear Import http://dx.doi.org/10.1038/mt.2009.127 Identification of Protein Cofactors Necessary for Sequence-specific Plasmid DNA Nuclear Import

Molecular Therapy advance online publication, June 16, 2009. doi:10.1038/mt.2009.127

Authors: Aaron M Miller, Felix M Munkonge, Eric WFW Alton & David A Dean

]]> Identification of Protein Cofactors Necessary for Sequence-specific Plasmid DNA Nuclear Import Aaron M Miller Felix M Munkonge Eric WFW Alton David A Dean doi:10.1038/mt.2009.127 Molecular Therapy advance online publication, June 16, 2009 2009-06-16 Molecular Therapy June 16, 2009 10.1038/mt.2009.127 http://dx.doi.org/10.1038/mt.2009.127 aop current A Simplified Baculovirus-AAV Expression Vector System Coupled With One-step Affinity Purification Yields High-titer rAAV Stocks From Insect Cells http://dx.doi.org/10.1038/mt.2009.128 A Simplified Baculovirus-AAV Expression Vector System Coupled With One-step Affinity Purification Yields High-titer rAAV Stocks From Insect Cells

Molecular Therapy advance online publication, June 16, 2009. doi:10.1038/mt.2009.128

Authors: Richard H Smith, Justin R Levy & Robert M Kotin

]]> A Simplified Baculovirus-AAV Expression Vector System Coupled With One-step Affinity Purification Yields High-titer rAAV Stocks From Insect Cells Richard H Smith Justin R Levy Robert M Kotin doi:10.1038/mt.2009.128 Molecular Therapy advance online publication, June 16, 2009 2009-06-16 Molecular Therapy June 16, 2009 10.1038/mt.2009.128 http://dx.doi.org/10.1038/mt.2009.128 aop current New Insights on Adenovirus as Vaccine Vectors http://dx.doi.org/10.1038/mt.2009.130 New Insights on Adenovirus as Vaccine Vectors

Molecular Therapy advance online publication, June 9, 2009. doi:10.1038/mt.2009.130

Authors: Marcio O Lasaro & Hildegund CJ Ertl

]]> New Insights on Adenovirus as Vaccine Vectors Marcio O Lasaro Hildegund CJ Ertl doi:10.1038/mt.2009.130 Molecular Therapy advance online publication, June 9, 2009 2009-06-09 Molecular Therapy June 9, 2009 10.1038/mt.2009.130 http://dx.doi.org/10.1038/mt.2009.130 aop current Immunotherapy for Osteosarcoma: Genetic Modification of T cells Overcomes Low Levels of Tumor Antigen Expression http://dx.doi.org/10.1038/mt.2009.133 Immunotherapy for Osteosarcoma: Genetic Modification of T cells Overcomes Low Levels of Tumor Antigen Expression

Molecular Therapy advance online publication, June 16, 2009. doi:10.1038/mt.2009.133

Authors: Nabil Ahmed, Vita S Salsman, Eric Yvon, Chrystal U Louis, Laszlo Perlaky, Winfried S Wels, Meghan K Dishop, Eugenie E Kleinerman, Martin Pule, Cliona M Rooney, Helen E Heslop & Stephen Gottschalk

]]> Immunotherapy for Osteosarcoma: Genetic Modification of T cells Overcomes Low Levels of Tumor Antigen Expression Nabil Ahmed Vita S Salsman Eric Yvon Chrystal U Louis Laszlo Perlaky Winfried S Wels Meghan K Dishop Eugenie E Kleinerman Martin Pule Cliona M Rooney Helen E Heslop Stephen Gottschalk doi:10.1038/mt.2009.133 Molecular Therapy advance online publication, June 16, 2009 2009-06-16 Molecular Therapy June 16, 2009 10.1038/mt.2009.133 http://dx.doi.org/10.1038/mt.2009.133 aop current Cell-intrinsic and Vector-related Properties Cooperate to Determine the Incidence and Consequences of Insertional Mutagenesis http://dx.doi.org/10.1038/mt.2009.134 Cell-intrinsic and Vector-related Properties Cooperate to Determine the Incidence and Consequences of Insertional Mutagenesis

Molecular Therapy advance online publication, June 16, 2009. doi:10.1038/mt.2009.134

Authors: Olga S Kustikova, Bernhard Schiedlmeier, Martijn H Brugman, Maike Stahlhut, Stefan Bartels, Zhixiong Li & Christopher Baum

]]> Cell-intrinsic and Vector-related Properties Cooperate to Determine the Incidence and Consequences of Insertional Mutagenesis Olga S Kustikova Bernhard Schiedlmeier Martijn H Brugman Maike Stahlhut Stefan Bartels Zhixiong Li Christopher Baum doi:10.1038/mt.2009.134 Molecular Therapy advance online publication, June 16, 2009 2009-06-16 Molecular Therapy June 16, 2009 10.1038/mt.2009.134 http://dx.doi.org/10.1038/mt.2009.134 aop current Sexually Dimorphic Patterns of Episomal rAAV Genome Persistence in the Adult Mouse Liver and Correlation With Hepatocellular Proliferation http://dx.doi.org/10.1038/mt.2009.139 Sexually Dimorphic Patterns of Episomal rAAV Genome Persistence in the Adult Mouse Liver and Correlation With Hepatocellular Proliferation

Molecular Therapy advance online publication, June 30, 2009. doi:10.1038/mt.2009.139

Authors: Allison P Dane, Sharon C Cunningham, Nicole S Graf & Ian E Alexander

]]> Sexually Dimorphic Patterns of Episomal rAAV Genome Persistence in the Adult Mouse Liver and Correlation With Hepatocellular Proliferation Allison P Dane Sharon C Cunningham Nicole S Graf Ian E Alexander doi:10.1038/mt.2009.139 Molecular Therapy advance online publication, June 30, 2009 2009-06-30 Molecular Therapy June 30, 2009 10.1038/mt.2009.139 http://dx.doi.org/10.1038/mt.2009.139 aop current Amelioration of Psoriasis by Anti-TNF-α RNAi in the Xenograft Transplantation Model http://dx.doi.org/10.1038/mt.2009.141 Amelioration of Psoriasis by Anti-TNF-α RNAi in the Xenograft Transplantation Model

Molecular Therapy advance online publication, June 30, 2009. doi:10.1038/mt.2009.141

Authors: Maria Jakobsen, Karin Stenderup, Cecilia Rosada, Brian Moldt, Søren Kamp, Tomas N Dam, Thomas G Jensen & Jacob Giehm Mikkelsen

]]> Amelioration of Psoriasis by Anti-TNF-α RNAi in the Xenograft Transplantation Model Maria Jakobsen Karin Stenderup Cecilia Rosada Brian Moldt Søren Kamp Tomas N Dam Thomas G Jensen Jacob Giehm Mikkelsen doi:10.1038/mt.2009.141 Molecular Therapy advance online publication, June 30, 2009 2009-06-30 Molecular Therapy June 30, 2009 10.1038/mt.2009.141 http://dx.doi.org/10.1038/mt.2009.141 aop current Biosafety in Ex Vivo Gene Therapy and Conditional Ablation of Lentivirally Transduced Hepatocytes in Nonhuman Primates http://dx.doi.org/10.1038/mt.2009.143 Biosafety in Ex Vivo Gene Therapy and Conditional Ablation of Lentivirally Transduced Hepatocytes in Nonhuman Primates

Molecular Therapy advance online publication, June 30, 2009. doi:10.1038/mt.2009.143

Authors: Olivier Menzel, Jacques Birraux, Barbara E Wildhaber, Caty Jond, Françoise Lasne, Walid Habre, Didier Trono, Tuan H Nguyen & Christophe Chardot

]]> Biosafety in Ex Vivo Gene Therapy and Conditional Ablation of Lentivirally Transduced Hepatocytes in Nonhuman Primates Olivier Menzel Jacques Birraux Barbara E Wildhaber Caty Jond Françoise Lasne Walid Habre Didier Trono Tuan H Nguyen Christophe Chardot doi:10.1038/mt.2009.143 Molecular Therapy advance online publication, June 30, 2009 2009-06-30 Molecular Therapy June 30, 2009 10.1038/mt.2009.143 http://dx.doi.org/10.1038/mt.2009.143 aop current Mechanisms of Fibroblast Cell Therapy for Dystrophic Epidermolysis Bullosa: High Stability of Collagen VII Favors Long-term Skin Integrity http://dx.doi.org/10.1038/mt.2009.144 Mechanisms of Fibroblast Cell Therapy for Dystrophic Epidermolysis Bullosa: High Stability of Collagen VII Favors Long-term Skin Integrity

Molecular Therapy advance online publication, June 30, 2009. doi:10.1038/mt.2009.144

Authors: Johannes S Kern, Stefan Loeckermann, Anja Fritsch, Ingrid Hausser, Wera Roth, Thomas M Magin, Claudia Mack, Marcel L Müller, Oliver Paul, Patrick Ruther & Leena Bruckner-Tuderman

]]> Mechanisms of Fibroblast Cell Therapy for Dystrophic Epidermolysis Bullosa: High Stability of Collagen VII Favors Long-term Skin Integrity Johannes S Kern Stefan Loeckermann Anja Fritsch Ingrid Hausser Wera Roth Thomas M Magin Claudia Mack Marcel L Müller Oliver Paul Patrick Ruther Leena Bruckner-Tuderman doi:10.1038/mt.2009.144 Molecular Therapy advance online publication, June 30, 2009 2009-06-30 Molecular Therapy June 30, 2009 10.1038/mt.2009.144 http://dx.doi.org/10.1038/mt.2009.144 aop current BH3-based Fusion Artificial Peptide Induces Apoptosis and Targets Human Colon Cancer http://dx.doi.org/10.1038/mt.2009.43 BH3-based Fusion Artificial Peptide Induces Apoptosis and Targets Human Colon Cancer

Molecular Therapy advance online publication, April 7, 2009. doi:10.1038/mt.2009.43

Authors: Yongjun Liu, Yunfeng Li, Haijuan Wang, Jing Yu, Hongwei Lin, Dongkui Xu, Yang Wang, Ailing Liang, Xiao Liang, Xueyan Zhang, Ming Fu, Haili Qian & Chen Lin

]]> BH3-based Fusion Artificial Peptide Induces Apoptosis and Targets Human Colon Cancer Yongjun Liu Yunfeng Li Haijuan Wang Jing Yu Hongwei Lin Dongkui Xu Yang Wang Ailing Liang Xiao Liang Xueyan Zhang Ming Fu Haili Qian Chen Lin doi:10.1038/mt.2009.43 Molecular Therapy advance online publication, April 7, 2009 Molecular Therapy April 7, 2009 10.1038/mt.2009.43 http://dx.doi.org/10.1038/mt.2009.43 aop current Rational Design of Antisense Oligomers to Induce Dystrophin Exon Skipping http://dx.doi.org/10.1038/mt.2009.49 Rational Design of Antisense Oligomers to Induce Dystrophin Exon Skipping

Molecular Therapy advance online publication, March 17, 2009. doi:10.1038/mt.2009.49

Authors: Chalermchai Mitrpant, Abbie M Adams, Penny L Meloni, Francesco Muntoni, Sue Fletcher & Steve D Wilton

]]> Rational Design of Antisense Oligomers to Induce Dystrophin Exon Skipping Chalermchai Mitrpant Abbie M Adams Penny L Meloni Francesco Muntoni Sue Fletcher Steve D Wilton doi:10.1038/mt.2009.49 Molecular Therapy advance online publication, March 17, 2009 2009-03-17 Molecular Therapy March 17, 2009 10.1038/mt.2009.49 http://dx.doi.org/10.1038/mt.2009.49 aop current Physiological Transgene Regulation and Functional Complementation of a Neurological Disease Gene Deficiency in Neurons http://dx.doi.org/10.1038/mt.2009.64 Physiological Transgene Regulation and Functional Complementation of a Neurological Disease Gene Deficiency in Neurons

Molecular Therapy advance online publication, April 7, 2009. doi:10.1038/mt.2009.64

Authors: Pier Paolo Peruzzi, Sean E Lawler, Steve L Senior, Nina Dmitrieva, Pauline AH Edser, Davide Gianni, E Antonio Chiocca & Richard Wade-Martins

]]> Physiological Transgene Regulation and Functional Complementation of a Neurological Disease Gene Deficiency in Neurons Pier Paolo Peruzzi Sean E Lawler Steve L Senior Nina Dmitrieva Pauline AH Edser Davide Gianni E Antonio Chiocca Richard Wade-Martins doi:10.1038/mt.2009.64 Molecular Therapy advance online publication, April 7, 2009 Molecular Therapy April 7, 2009 10.1038/mt.2009.64 http://dx.doi.org/10.1038/mt.2009.64 aop current The Sea Urchin sns5 Insulator Protects Retroviral Vectors From Chromosomal Position Effects by Maintaining Active Chromatin Structure http://dx.doi.org/10.1038/mt.2009.74 The Sea Urchin sns5 Insulator Protects Retroviral Vectors From Chromosomal Position Effects by Maintaining Active Chromatin Structure

Molecular Therapy advance online publication, April 7, 2009. doi:10.1038/mt.2009.74

Authors: Danilo D'Apolito, Elena Baiamonte, Mariella Bagliesi, Rosalba Di Marzo, Roberta Calzolari, Leda Ferro, Vito Franco, Giovanni Spinelli, Aurelio Maggio & Santina Acuto

]]> The Sea Urchin sns5 Insulator Protects Retroviral Vectors From Chromosomal Position Effects by Maintaining Active Chromatin Structure Danilo D'Apolito Elena Baiamonte Mariella Bagliesi Rosalba Di Marzo Roberta Calzolari Leda Ferro Vito Franco Giovanni Spinelli Aurelio Maggio Santina Acuto doi:10.1038/mt.2009.74 Molecular Therapy advance online publication, April 7, 2009 Molecular Therapy April 7, 2009 10.1038/mt.2009.74 http://dx.doi.org/10.1038/mt.2009.74 aop current Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo http://dx.doi.org/10.1038/mt.2009.83 Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo

Molecular Therapy advance online publication, April 21, 2009. doi:10.1038/mt.2009.83

Authors: Michael C. Milone, Jonathan D. Fish, Carmine Carpenito, Richard G. Carroll, Gwendolyn K. Binder, David Teachey, Minu Samanta, Mehdi Lakhal, Brian Gloss, Gwenn Danet-Desnoyers, Dario Campana, James L. Riley, Stephan A. Grupp & Carl H. June

]]> Chimeric Receptors Containing CD137 Signal Transduction Domains Mediate Enhanced Survival of T Cells and Increased Antileukemic Efficacy In Vivo Michael C. Milone Jonathan D. Fish Carmine Carpenito Richard G. Carroll Gwendolyn K. Binder David Teachey Minu Samanta Mehdi Lakhal Brian Gloss Gwenn Danet-Desnoyers Dario Campana James L. Riley Stephan A. Grupp Carl H. June doi:10.1038/mt.2009.83 Molecular Therapy advance online publication, April 21, 2009 2009-04-21 Molecular Therapy April 21, 2009 10.1038/mt.2009.83 http://dx.doi.org/10.1038/mt.2009.83 aop current DNA/Amphiphilic Block Copolymer Nanospheres Promote Low-dose DNA Vaccination http://dx.doi.org/10.1038/mt.2009.84 DNA/Amphiphilic Block Copolymer Nanospheres Promote Low-dose DNA Vaccination

Molecular Therapy advance online publication, May 5, 2009. doi:10.1038/mt.2009.84

Authors: Dorian McIlroy, Benoît Barteau, Jeannette Cany, Peggy Richard, Clothilde Gourden, Sophie Conchon & Bruno Pitard

]]> DNA/Amphiphilic Block Copolymer Nanospheres Promote Low-dose DNA Vaccination Dorian McIlroy Benoît Barteau Jeannette Cany Peggy Richard Clothilde Gourden Sophie Conchon Bruno Pitard doi:10.1038/mt.2009.84 Molecular Therapy advance online publication, May 5, 2009 2009-05-05 Molecular Therapy May 5, 2009 10.1038/mt.2009.84 http://dx.doi.org/10.1038/mt.2009.84 aop current AAV2/8-mediated Correction of OTC Deficiency Is Robust in Adult but Not Neonatal Spfash Mice http://dx.doi.org/10.1038/mt.2009.88 AAV2/8-mediated Correction of OTC Deficiency Is Robust in Adult but Not Neonatal Spfash Mice

Molecular Therapy advance online publication, April 21, 2009. doi:10.1038/mt.2009.88

Authors: Sharon C Cunningham, Afroditi Spinoulas, Kevin H Carpenter, Bridget Wilcken, Philip W Kuchel & Ian E Alexander

]]> AAV2/8-mediated Correction of OTC Deficiency Is Robust in Adult but Not Neonatal Spfash Mice Sharon C Cunningham Afroditi Spinoulas Kevin H Carpenter Bridget Wilcken Philip W Kuchel Ian E Alexander doi:10.1038/mt.2009.88 Molecular Therapy advance online publication, April 21, 2009 2009-04-21 Molecular Therapy April 21, 2009 10.1038/mt.2009.88 http://dx.doi.org/10.1038/mt.2009.88 aop current Mechanism of Reduction in Titers From Lentivirus Vectors Carrying Large Inserts in the 3′LTR http://dx.doi.org/10.1038/mt.2009.89 Mechanism of Reduction in Titers From Lentivirus Vectors Carrying Large Inserts in the 3′LTR

Molecular Therapy advance online publication, April 21, 2009. doi:10.1038/mt.2009.89

Authors: Fabrizia Urbinati, Paritha Arumugam, Tomoyasu Higashimoto, Anil Perumbeti, Kyle Mitts, Ping Xia & Punam Malik

]]> Mechanism of Reduction in Titers From Lentivirus Vectors Carrying Large Inserts in the 3′LTR Fabrizia Urbinati Paritha Arumugam Tomoyasu Higashimoto Anil Perumbeti Kyle Mitts Ping Xia Punam Malik doi:10.1038/mt.2009.89 Molecular Therapy advance online publication, April 21, 2009 2009-04-21 Molecular Therapy April 21, 2009 10.1038/mt.2009.89 http://dx.doi.org/10.1038/mt.2009.89 aop current Heat Shock Protein 27 as a New Therapeutic Target for Radiation Sensitization of Head and Neck Squamous Cell Carcinoma http://dx.doi.org/10.1038/mt.2009.90 Heat Shock Protein 27 as a New Therapeutic Target for Radiation Sensitization of Head and Neck Squamous Cell Carcinoma

Molecular Therapy advance online publication, May 12, 2009. doi:10.1038/mt.2009.90

Authors: Elie Hadchity, Marie-Thérèse Aloy, Christian Paulin, Emma Armandy, Emmanuel Watkin, Robert Rousson, Martin Gleave, Olivier Chapet & Claire Rodriguez-Lafrasse

]]> Heat Shock Protein 27 as a New Therapeutic Target for Radiation Sensitization of Head and Neck Squamous Cell Carcinoma Elie Hadchity Marie-Thérèse Aloy Christian Paulin Emma Armandy Emmanuel Watkin Robert Rousson Martin Gleave Olivier Chapet Claire Rodriguez-Lafrasse doi:10.1038/mt.2009.90 Molecular Therapy advance online publication, May 12, 2009 2009-05-12 Molecular Therapy May 12, 2009 10.1038/mt.2009.90 http://dx.doi.org/10.1038/mt.2009.90 aop current Converting Tumor-specific Markers Into Reporters of Oncolytic Virus Infection http://dx.doi.org/10.1038/mt.2009.92 Converting Tumor-specific Markers Into Reporters of Oncolytic Virus Infection

Molecular Therapy advance online publication, May 26, 2009. doi:10.1038/mt.2009.92

Authors: Ianko D Iankov, Matthew L Hillestad, Allan B Dietz, Stephen J Russell & Evanthia Galanis

]]> Converting Tumor-specific Markers Into Reporters of Oncolytic Virus Infection Ianko D Iankov Matthew L Hillestad Allan B Dietz Stephen J Russell Evanthia Galanis doi:10.1038/mt.2009.92 Molecular Therapy advance online publication, May 26, 2009 2009-05-26 Molecular Therapy May 26, 2009 10.1038/mt.2009.92 http://dx.doi.org/10.1038/mt.2009.92 aop current Recombinant Vesicular Stomatitis Virus Transduction of Dendritic Cells Enhances Their Ability to Prime Innate and Adaptive Antitumor Immunity http://dx.doi.org/10.1038/mt.2009.95 Recombinant Vesicular Stomatitis Virus Transduction of Dendritic Cells Enhances Their Ability to Prime Innate and Adaptive Antitumor Immunity

Molecular Therapy advance online publication, April 28, 2009. doi:10.1038/mt.2009.95

Authors: Jeanette E Boudreau, Byram W Bridle, Kyle B Stephenson, Kristina M Jenkins, Jérôme Brunellière, Jonathan L Bramson, Brian D Lichty & Yonghong Wan

]]> Recombinant Vesicular Stomatitis Virus Transduction of Dendritic Cells Enhances Their Ability to Prime Innate and Adaptive Antitumor Immunity Jeanette E Boudreau Byram W Bridle Kyle B Stephenson Kristina M Jenkins Jérôme Brunellière Jonathan L Bramson Brian D Lichty Yonghong Wan doi:10.1038/mt.2009.95 Molecular Therapy advance online publication, April 28, 2009 2009-04-28 Molecular Therapy April 28, 2009 10.1038/mt.2009.95 http://dx.doi.org/10.1038/mt.2009.95 aop current