ADVANCE ONLINE PUBLICATION

The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
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July 22 2008

Original Article

Histone Deacetylase Inhibitors Augment Antitumor Efficacy of Herpes-based Oncolytic Viruses

Akihiro Otsuki, Ankita Patel, Kazue Kasai, Masataka Suzuki, Kazuhiko Kurozumi, E Antonio Chiocca and Yoshinaga Saeki

Mol Ther advance online publication, July 22, 2008; doi:10.1038/mt.2008.155

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July 15 2008

Review

Advances in High-capacity Extrachromosomal Vector Technology: Episomal Maintenance, Vector Delivery, and Transgene Expression

Michele MP Lufino, Pauline AH Edser and Richard Wade-Martins

Mol Ther advance online publication, July 15, 2008; doi:10.1038/mt.2008.156

Original Articles

RNA Interference Screen to Identify Pathways That Enhance or Reduce Nonviral Gene Transfer During Lipofection

Gregory A Barker and Scott L Diamond

Mol Ther advance online publication, July 15, 2008; doi:10.1038/mt.2008.147

The Targeted Oncolytic Poxvirus JX-594 Demonstrates Antitumoral, Antivascular, and Anti-HBV Activities in Patients With Hepatocellular Carcinoma

Ta-Chiang Liu, Taeho Hwang, Byeong-Ho Park, John Bell and David H Kirn

Mol Ther advance online publication, July 15, 2008; doi:10.1038/mt.2008.143

Intranigral Lentiviral Delivery of Dominant-negative TNF Attenuates Neurodegeneration and Behavioral Deficits in Hemiparkinsonian rats

Melissa K McCoy, Kelly A Ruhn, Terina N Martinez, Fiona E McAlpine, Armin Blesch and Malú G Tansey

Mol Ther advance online publication, July 15, 2008; doi:10.1038/mt.2008.146

Acid Sphingomyelinase Overexpression Enhances the Antineoplastic Effects of Irradiation In Vitro and In Vivo

Eric L Smith and Edward H Schuchman

Mol Ther advance online publication, July 15, 2008; doi:10.1038/mt.2008.145

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July 8 2008

Original Article

The Immunogenicity of Adenovirus Vectors Limits the Multispecificity of CD8 T-cell Responses to Vector-encoded Transgenic Antigens

Reinhold Schirmbeck, Jörg Reimann, Stefan Kochanek and Florian Kreppel

Mol Ther advance online publication, July 8, 2008; doi:10.1038/mt.2008.141

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July 1 2008

Original Article

Viral Vector–mediated Delivery of Estrogen Receptor-alpha to the Hippocampus Improves Spatial Learning in Estrogen Receptor-alpha Knockout Mice

Thomas C Foster, Asha Rani, Ashok Kumar, Li Cui and Susan L Semple-Rowland

Mol Ther advance online publication, July 1, 2008; doi:10.1038/mt.2008.140

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June 24 2008

Original Articles

Double Oxygen–sensing Vector System for Robust Hypoxia/Ischemia-regulated Gene Induction in Cardiac Muscle In Vitro and In Vivo

Ekaterina V Fomicheva, Immanuel I Turner, Terri G Edwards, Janet Hoff, Eric Arden, Louis G D'Alecy and Joseph M Metzger

Mol Ther advance online publication, June 24, 2008; doi:10.1038/mt.2008.136

Reduced Genotoxicity of Avian Sarcoma Leukosis Virus Vectors in Rhesus Long-term Repopulating Cells Compared to Standard Murine Retrovirus Vectors

Jingqiong Hu, Gabriel Renaud, Theotonius Golmes, Andrea Ferris, Paul C Hendrie, Robert E Donahue, Stephen H Hughes, Tyra G Wolfsberg, David W Russell and Cynthia E Dunbar

Mol Ther advance online publication, June 24, 2008; doi:10.1038/mt.2008.135

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June 10 2008

Original Article

Sustained Dystrophin Expression Induced by Peptide-conjugated Morpholino Oligomers in the Muscles of mdx Mice

Natee Jearawiriyapaisarn, Hong M Moulton, Brian Buckley, Jennifer Roberts, Peter Sazani, Suthat Fucharoen, Patrick L Iversen and Ryszard Kole

Mol Ther advance online publication, June 10, 2008; doi:10.1038/mt.2008.120

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February 12 2008

Original Articles

Intraventricular Enzyme Replacement Improves Disease Phenotypes in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis

Michael Chang, Jonathan D Cooper, David E Sleat, Seng H Cheng, James C Dodge, Marco A Passini, Peter Lobel and Beverly L Davidson

Mol Ther advance online publication, February 12, 2008; doi:10.1038/sj.mt.6300415

Gene Therapy of betac-Deficient Pulmonary Alveolar Proteinosis (betac-PAP): Studies in a Murine in vivo Model

Veronika Kleff, Ursula R Sorg, Carsten Bury, Takuji Suzuki, Ina Rattmann, Moran Jerabek-Willemsen, Christopher Poremba, Michael Flasshove, Bertram Opalka, Bruce Trapnell, Uta Dirksen and Thomas Moritz

Mol Ther advance online publication, February 12, 2008; doi:10.1038/mt.2008.7

Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of alpha-Tocopherol

Kazutaka Nishina, Toshinori Unno, Yoshitaka Uno, Takayuki Kubodera, Tadashi Kanouchi, Hidehiro Mizusawa and Takanori Yokota

Mol Ther advance online publication, February 12, 2008; doi:10.1038/sj.mt.6300420

Bovine Adenoviral Vector–based H5N1 Influenza Vaccine Overcomes Exceptionally High Levels of Pre-existing Immunity Against Human Adenovirus

Neetu Singh, Aseem Pandey, Lakshmi Jayashankar and Suresh K Mittal

Mol Ther advance online publication, February 12, 2008; doi:10.1038/mt.2008.11

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February 5 2008

Ranibizumab for Macular Edema Due to Retinal Vein Occlusions; Implication of VEGF as a Critical Stimulator

Peter A Campochiaro, Gulnar Hafiz, Syed Mahmood Shah, Quan Dong Nguyen, Howard Ying, Diana V Do, Edward Quinlan, Ingrid Zimmer-Galler, Julia A Haller, Sharon D Solomon, Jennifer U Sung, Yasmin Hadi, Kashif A Janjua, Nida Jawed, David F Choy and Joseph R Arron

Mol Ther advance online publication, February 5, 2008; doi:10.1038/sj.mt.6300416

A Tumor-selective Biotherapy With Prolonged Impact on Established Metastases Based on Cytokine Gene-engineered MSCs

Xiancheng Chen, Xiaojuan Lin, Jianlei Zhao, Wei Shi, Heng Zhang, Yongsheng Wang, Bing Kan, Licheng Du, Baiding Wang, Yuquan Wei, Yi Liu and Xia Zhao

Mol Ther advance online publication, February 5, 2008; doi:10.1038/sj.mt.6300409

Phase I Clinical Trial of Autologous Ascites-derived Exosomes Combined With GM-CSF for Colorectal Cancer

Shengming Dai, Dong Wei, Zhen Wu, Xiangyang Zhou, Xiaomou Wei, Haixin Huang and Guisheng Li

Mol Ther advance online publication, February 5, 2008; doi:10.1038/sj.mt.6300407

TAT-mediated Delivery of LAD Restores Pyruvate Dehydrogenase Complex Activity in the Mitochondria of Patients with LAD Deficiency

Matan Rapoport, Ann Saada, Orly Elpeleg and Haya Lorberboum-Galski

Mol Ther advance online publication, February 5, 2008; doi:10.1038/sj.mt.6300410

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