TABLE OF CONTENTS

Volume 9, Issue 6 (June 2004)

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Editorial

Visa Crisis Hurts U.S. Science

Inder M. Verma

Mol Ther 9: 767; doi:10.1016/j.ymthe.2004.05.009

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Inside this Month

Inside this Month

Mol Ther 9: 768; doi:10.1016/j.ymthe.2004.05.008

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Research Update

Research Update

Mol Ther 9: 769-770; doi:10.1016/j.ymthe.2004.05.010

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Perspective

Input Virion Proteins: Cryptic Targets of Antivector Immune Responses in Preimmunized Subjects

Pedro R. Lowenstein

Mol Ther 9: 771-774; doi:10.1016/j.ymthe.2004.05.019

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Original Articles

Novel Mouse Model for Carcinoembryonic Antigen-based Therapy

Carlos H. F. Chan and Clifford P. Stanners

Mol Ther 9: 775-785; doi:10.1016/j.ymthe.2004.03.009

An E1B-19 kDa Gene Deletion Mutant Adenovirus Demonstrates Tumor Necrosis Factor-Enhanced Cancer Selectivity and Enhanced Oncolytic Potency

Ta-Chiang Liu, Gunnel Hallden, Yaohe Wang, Gabriel Brooks, Jennelle Francis, Nick Lemoine and David Kirn

Mol Ther 9: 786-803; doi:10.1016/j.ymthe.2004.03.017

A Conditionally Replicating Adenovirus for Nasopharyngeal Carcinoma Gene Therapy

Marie C. Chia, Wei Shi, Jian-Hua Li, Otto Sanchez, Craig A. Strathdee, Dolly Huang, Pierre Busson, Henry J. Klamut and Fei-Fei Liu

Mol Ther 9: 804-817; doi:10.1016/j.ymthe.2004.03.016

Adenovirus-Mediated mda-7 (IL24) Gene Therapy Suppresses Angiogenesis and Sensitizes NSCLC Xenograft Tumors to Radiation

Takashi Nishikawa, Rajagopal Ramesh, Anupama Munshi, Sunil Chada and Raymond E. Meyn

Mol Ther 9: 818-828; doi:10.1016/j.ymthe.2004.03.014

Combination of Local, Nonviral IL12 Gene Therapy and Systemic Paclitaxel Treatment in a Metastatic Breast Cancer Model

Margit Maria Janát-Amsbury, James W. Yockman, Minhyung Lee, Steven Kern, Darin Y. Furgeson, Malavosklish Bikram and Sung Wan Kim

Mol Ther 9: 829-836; doi:10.1016/j.ymthe.2004.03.015

Tumor Efficacy and Biodistribution of Linear Polyethylenimine-Cholesterol/DNA Complexes

Darin Y. Furgeson, James W. Yockman, Margit-Maria Janat and Sung Wan Kim

Mol Ther 9: 837-845; doi:10.1016/j.ymthe.2004.02.014

The Angiostatic Activity of Interferon-Inducible Protein-10/CXCL10 in Human Melanoma Depends on Binding to CXCR3 but Not to Glycosaminoglycan

Jinming Yang and Ann Richmond

Mol Ther 9: 846-855; doi:10.1016/j.ymthe.2004.01.010

Human CD34+ Hematopoietic Progenitor Cell-Directed Lentiviral-Mediated Gene Therapy in a Xenotransplantation Model of Lysosomal Storage Disease

A. Alex Hofling, Steven Devine, Carole Vogler and Mark S. Sands

Mol Ther 9: 856-865; doi:10.1016/j.ymthe.2004.03.013

Correction of Metabolic, Craniofacial, and Neurologic Abnormalities in MPS I Mice Treated at Birth with Adeno-associated Virus Vector Transducing the Human alpha-L-Iduronidase Gene

Seth D. Hartung, Joel L. Frandsen, Dao Pan, Brenda L. Koniar, Patrick Graupman, Roland Gunther, Walter C. Low, Chester B. Whitley and R. Scott McIvor

Mol Ther 9: 866-875; doi:10.1016/j.ymthe.2004.03.011

Potent Inhibition of Arterial Intimal Hyperplasia by TIMP1 Gene Transfer using AAV vectors

Genaro A. Ramirez Correa, Serena Zacchigna, Nikola Arsic, Lorena Zentilin, Alessandro Salvi, Gianfranco Sinagra and Mauro Giacca

Mol Ther 9: 876-884; doi:10.1016/j.ymthe.2004.02.020

Development of a Self-inactivating Tet-on Retroviral Vector Expressing Bone Morphogenetic Protein 4 to Achieve Regulated Bone Formation

Hairong Peng, Arvydas Usas, Brian Gearhart, Brett Young, Anne Olshanski and Johnny Huard

Mol Ther 9: 885-894; doi:10.1016/j.ymthe.2004.02.023

Retroviral-mediated Gene Transfer Restores IL-12 and IL-23 Signaling Pathways in T cells from IL-12 Receptor beta1-deficient Patients

Marita Bosticardo, Iren Witte, Claire Fieschi, Francesco Novelli, Jean-Laurent Casanova and Fabio Candotti

Mol Ther 9: 895-901; doi:10.1016/j.ymthe.2004.02.024

Efficient Lentiviral Vector-mediated Control of HIV-1 Replication in CD4 Lymphocytes from Diverse HIV+ Infected Patients Grouped According to CD4 Count and Viral Load

Laurent M. Humeau, Gwendolyn K. Binder, Xiaobin Lu, Vladimir Slepushkin, Randall Merling, Patricia Echeagaray, Mario Pereira, Tatiana Slepushkina, Scott Barnett, Lesia K. Dropulic, Richard Carroll, Bruce L. Levine, Carl H. June and Boro Dropulic

Mol Ther 9: 902-913; doi:10.1016/j.ymthe.2004.03.005

Efficient Marking of Murine Long-Term Repopulating Stem Cells Targeting Unseparated Marrow Cells at Low Lentiviral Vector Particle Concentration

Peter Kurre, Ponni Anandakumar, Michael A. Harkey, Bobbie Thomasson and Hans-Peter Kiem

Mol Ther 9: 914-922; doi:10.1016/j.ymthe.2004.03.008

Limited Lentiviral Transgene Expression with Increasing Copy Number in an MGMT Selection Model: Lack of Copy Number Selection by Drug Treatment

Steven P. Zielske, Karen T. Lingas, Yan Li and Stanton L. Gerson

Mol Ther 9: 923-931; doi:10.1016/j.ymthe.2004.02.017

Severe Pulmonary Pathology after Intravenous Administration of Vectors in Cirrhotic Rats

Jeffrey S. Smith, Jie Tian, Jay N. Lozier and Andrew P. Byrnes

Mol Ther 9: 932-941; doi:10.1016/j.ymthe.2004.03.010

Avidin-based Targeting and Purification of a Protein IX-modified, Metabolically Biotinylated Adenoviral Vector

Samuel K. Campos, M. Brandon Parrott and Michael A. Barry

Mol Ther 9: 942-954; doi:10.1016/j.ymthe.2004.03.006

The Fate of Mesenchymal Stem Cells Transplanted into Immunocompetent Neonatal Mice: Implications for Skeletal Gene Therapy via Stem Cells

Christopher Niyibizi, Sujing Wang, Zhibao Mi and Paul D. Robbins

Mol Ther 9: 955-963; doi:10.1016/j.ymthe.2004.02.022

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Method

Intracytoplasmic Delivery of Anionic Proteins

Deniz Dalkara, Guy Zuber and Jean-Paul Behr

Mol Ther 9: 964-969; doi:10.1016/j.ymthe.2004.03.007

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