TABLE OF CONTENTS
Volume 9, Issue 6 (June 2004)
Editorial
Visa Crisis Hurts U.S. Science
Inder M. Verma
Mol Ther 9: 767; doi:10.1016/j.ymthe.2004.05.009
Inside this Month
Top of pageResearch Update
Top of pagePerspective
Input Virion Proteins: Cryptic Targets of Antivector Immune Responses in Preimmunized Subjects
Pedro R. Lowenstein
Mol Ther 9: 771-774; doi:10.1016/j.ymthe.2004.05.019
Original Articles
Novel Mouse Model for Carcinoembryonic Antigen-based Therapy
Carlos H. F. Chan and Clifford P. Stanners
Mol Ther 9: 775-785; doi:10.1016/j.ymthe.2004.03.009
An E1B-19 kDa Gene Deletion Mutant Adenovirus Demonstrates Tumor Necrosis Factor-Enhanced Cancer Selectivity and Enhanced Oncolytic Potency
Ta-Chiang Liu, Gunnel Hallden, Yaohe Wang, Gabriel Brooks, Jennelle Francis, Nick Lemoine and David Kirn
Mol Ther 9: 786-803; doi:10.1016/j.ymthe.2004.03.017
A Conditionally Replicating Adenovirus for Nasopharyngeal Carcinoma Gene Therapy
Marie C. Chia, Wei Shi, Jian-Hua Li, Otto Sanchez, Craig A. Strathdee, Dolly Huang, Pierre Busson, Henry J. Klamut and Fei-Fei Liu
Mol Ther 9: 804-817; doi:10.1016/j.ymthe.2004.03.016
Adenovirus-Mediated mda-7 (IL24) Gene Therapy Suppresses Angiogenesis and Sensitizes NSCLC Xenograft Tumors to Radiation
Takashi Nishikawa, Rajagopal Ramesh, Anupama Munshi, Sunil Chada and Raymond E. Meyn
Mol Ther 9: 818-828; doi:10.1016/j.ymthe.2004.03.014
Combination of Local, Nonviral IL12 Gene Therapy and Systemic Paclitaxel Treatment in a Metastatic Breast Cancer Model
Margit Maria Janát-Amsbury, James W. Yockman, Minhyung Lee, Steven Kern, Darin Y. Furgeson, Malavosklish Bikram and Sung Wan Kim
Mol Ther 9: 829-836; doi:10.1016/j.ymthe.2004.03.015
Tumor Efficacy and Biodistribution of Linear Polyethylenimine-Cholesterol/DNA Complexes
Darin Y. Furgeson, James W. Yockman, Margit-Maria Janat and Sung Wan Kim
Mol Ther 9: 837-845; doi:10.1016/j.ymthe.2004.02.014
The Angiostatic Activity of Interferon-Inducible Protein-10/CXCL10 in Human Melanoma Depends on Binding to CXCR3 but Not to Glycosaminoglycan
Jinming Yang and Ann Richmond
Mol Ther 9: 846-855; doi:10.1016/j.ymthe.2004.01.010
Human CD34+ Hematopoietic Progenitor Cell-Directed Lentiviral-Mediated Gene Therapy in a Xenotransplantation Model of Lysosomal Storage Disease
A. Alex Hofling, Steven Devine, Carole Vogler and Mark S. Sands
Mol Ther 9: 856-865; doi:10.1016/j.ymthe.2004.03.013
Correction of Metabolic, Craniofacial, and Neurologic Abnormalities in MPS I Mice Treated at Birth with Adeno-associated Virus Vector Transducing the Human
-L-Iduronidase Gene
Seth D. Hartung, Joel L. Frandsen, Dao Pan, Brenda L. Koniar, Patrick Graupman, Roland Gunther, Walter C. Low, Chester B. Whitley and R. Scott McIvor
Mol Ther 9: 866-875; doi:10.1016/j.ymthe.2004.03.011
Potent Inhibition of Arterial Intimal Hyperplasia by TIMP1 Gene Transfer using AAV vectors
Genaro A. Ramirez Correa, Serena Zacchigna, Nikola Arsic, Lorena Zentilin, Alessandro Salvi, Gianfranco Sinagra and Mauro Giacca
Mol Ther 9: 876-884; doi:10.1016/j.ymthe.2004.02.020
Development of a Self-inactivating Tet-on Retroviral Vector Expressing Bone Morphogenetic Protein 4 to Achieve Regulated Bone Formation
Hairong Peng, Arvydas Usas, Brian Gearhart, Brett Young, Anne Olshanski and Johnny Huard
Mol Ther 9: 885-894; doi:10.1016/j.ymthe.2004.02.023
Retroviral-mediated Gene Transfer Restores IL-12 and IL-23 Signaling Pathways in T cells from IL-12 Receptor
1-deficient Patients
Marita Bosticardo, Iren Witte, Claire Fieschi, Francesco Novelli, Jean-Laurent Casanova and Fabio Candotti
Mol Ther 9: 895-901; doi:10.1016/j.ymthe.2004.02.024
Efficient Lentiviral Vector-mediated Control of HIV-1 Replication in CD4 Lymphocytes from Diverse HIV+ Infected Patients Grouped According to CD4 Count and Viral Load
Laurent M. Humeau, Gwendolyn K. Binder, Xiaobin Lu, Vladimir Slepushkin, Randall Merling, Patricia Echeagaray, Mario Pereira, Tatiana Slepushkina, Scott Barnett, Lesia K. Dropulic, Richard Carroll, Bruce L. Levine, Carl H. June and Boro Dropulic
Mol Ther 9: 902-913; doi:10.1016/j.ymthe.2004.03.005
Efficient Marking of Murine Long-Term Repopulating Stem Cells Targeting Unseparated Marrow Cells at Low Lentiviral Vector Particle Concentration
Peter Kurre, Ponni Anandakumar, Michael A. Harkey, Bobbie Thomasson and Hans-Peter Kiem
Mol Ther 9: 914-922; doi:10.1016/j.ymthe.2004.03.008
Limited Lentiviral Transgene Expression with Increasing Copy Number in an MGMT Selection Model: Lack of Copy Number Selection by Drug Treatment
Steven P. Zielske, Karen T. Lingas, Yan Li and Stanton L. Gerson
Mol Ther 9: 923-931; doi:10.1016/j.ymthe.2004.02.017
Severe Pulmonary Pathology after Intravenous Administration of Vectors in Cirrhotic Rats
Jeffrey S. Smith, Jie Tian, Jay N. Lozier and Andrew P. Byrnes
Mol Ther 9: 932-941; doi:10.1016/j.ymthe.2004.03.010
Avidin-based Targeting and Purification of a Protein IX-modified, Metabolically Biotinylated Adenoviral Vector
Samuel K. Campos, M. Brandon Parrott and Michael A. Barry
Mol Ther 9: 942-954; doi:10.1016/j.ymthe.2004.03.006
The Fate of Mesenchymal Stem Cells Transplanted into Immunocompetent Neonatal Mice: Implications for Skeletal Gene Therapy via Stem Cells
Christopher Niyibizi, Sujing Wang, Zhibao Mi and Paul D. Robbins
Mol Ther 9: 955-963; doi:10.1016/j.ymthe.2004.02.022
Method
Intracytoplasmic Delivery of Anionic Proteins
Deniz Dalkara, Guy Zuber and Jean-Paul Behr
Mol Ther 9: 964-969; doi:10.1016/j.ymthe.2004.03.007

