Molecular Therapy

FIGURE 2

FROM:

Correction of Metabolic, Craniofacial, and Neurologic Abnormalities in MPS I Mice Treated at Birth with Adeno-associated Virus Vector Transducing the Human alpha-L-Iduronidase Gene

Seth D. Hartung, Joel L. Frandsen, Dao Pan, Brenda L. Koniar, Patrick Graupman, Roland Gunther, Walter C. Low, Chester B. Whitley and R. Scott McIvor

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Figure 2.

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Effects of AAV-IDUA treatment on Idua -/- weights. Animals were weighed every 4 weeks beginning 1 month after vector injection. Bars depict the mean percentage difference from same sex Idua +/- control (plusminusSEM) for n = 6 animals per group. At each time point, the heterozygous control group is defined as 100%.

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