FIGURE 4
FROM:
Quantitative Assessment of Human Endometriotic Tissue Maintenance and Regression in a Noninvasive Mouse Model of Endometriosis
Marylène Fortin, Manon Lépine, Yannick Merlen, Isabelle Thibeault, Claudine Rancourt, Diane Gosselin, Patrice Hugo and Ann-Muriel Steff
BACK TO ARTICLEFigure 4.
Ganciclovir treatment induces cell death in an endometrial cell line expressing the thymidine kinase gene. HEC-1A cells were infected with either AdGFP or AdTK viral particles at an m.o.i. of 1. The proportions of cells expressing either GFP or TK 1 day prior to GCV treatment were 76 and 24%, respectively. Treatment with increasing doses of ganciclovir (GCV) was initiated 5 days postinfection and was pursued for 7 days. At the end of GCV treatment, cells were harvested and cell death was assessed by propidium iodide (PI) staining and flow cytometry. The percentage of apoptotic cells for each GCV dose is shown.
