TABLE OF CONTENTS

Volume 9, Issue 2 (February 2004)

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Editorial

AIDS: No End in Sight

Inder M. Verma

Mol Ther 9: 141; doi:10.1016/j.ymthe.2004.01.002

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Inside this Month

Inside this Month

Mol Ther 9: 142; doi:10.1016/j.ymthe.2004.01.003

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Research Update

Research Update

Mol Ther 9: 143; doi:10.1016/j.ymthe.2004.01.004

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Meeting Report

Meeting Report

Mol Ther 9: 144-146; doi:10.1016/j.ymthe.2004.01.001

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Review

Sleeping Beauty Transposition: Biology and Applications for Molecular Therapy

Zsuzsanna Izsvák and Zoltán Ivics

Mol Ther 9: 147-156; doi:10.1016/j.ymthe.2003.11.009

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Letter to the Editor

Efficient Gene Transfer to Hematopoietic Repopulating Cells Using Concentrated RD114-Pseudotype Vectors Produced by Human Packaging Cells

Tobias Neff, Laura J. Peterson, Julia C. Morris, Jesse Thompson, Xiaobing Zhang, Peter A. Horn, Bobbie M. Thomasson and Hans-Peter Kiem

Mol Ther 9: 157-159; doi:10.1016/j.ymthe.2003.11.011

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Original Articles

In Vivo Selection for Human and Murine Hematopoietic Cells Transduced with a Therapeutic MGMT Lentiviral Vector that Inhibits HIV Replication

Brian M. Davis, Laurent Humeau and Boro Dropulic

Mol Ther 9: 160-172; doi:10.1016/j.ymthe.2003.11.003

Antioxidant Gene Therapy Can Protect Hearing and Hair Cells from Ototoxicity

Kohei Kawamoto, Su-Hua Sha, Ryosei Minoda, Masahiko Izumikawa, Hiromichi Kuriyama, Jochen Schacht and Yehoash Raphael

Mol Ther 9: 173-181; doi:10.1016/j.ymthe.2003.11.020

In Utero Gene Therapy Rescues Vision in a Murine Model of Congenital Blindness

Nadine S. Dejneka, Enrico M. Surace, Tomas S. Aleman, Artur V. Cideciyan, Arkady Lyubarsky, Andrey Savchenko, T. Michael Redmond, Waixing Tang, Zhangyong Wei, Tonia S. Rex, Ernest Glover, Albert M. Maguire, Edward N. Pugh Jr., Samuel G. Jacobson and Jean Bennett

Mol Ther 9: 182-188; doi:10.1016/j.ymthe.2003.11.013

BDNF Gene-Modified Mesenchymal Stem Cells Promote Functional Recovery and Reduce Infarct Size in the Rat Middle Cerebral Artery Occlusion Model

Kazuhiko Kurozumi, Kiminori Nakamura, Takashi Tamiya, Yutaka Kawano, Masayoshi Kobune, Sachie Hirai, Hiroaki Uchida, Katsunori Sasaki, Yoshinori Ito, Kazunori Kato, Osamu Honmou, Kiyohiro Houkin, Isao Date and Hirofumi Hamada

Mol Ther 9: 189-197; doi:10.1016/j.ymthe.2003.10.012

Development of Efficient Viral Vectors Selective for Vascular Smooth Muscle Cells

Lorraine M. Work, Stuart A. Nicklin, Nick J. R. Brain, Kate L. Dishart, Dan J. Von Seggern, Michael Hallek, Hildegard Büning and Andrew H. Baker

Mol Ther 9: 198-208; doi:10.1016/j.ymthe.2003.11.006

Lentiviral Vectors Efficiently Transduce Quiescent Mature 3T3-L1 Adipocytes

Françoise Carlotti, Merlijn Bazuine, Tuija Kekarainen, Jurgen Seppen, Philippe Pognonec, J.Antonie Maassen and Rob C. Hoeben

Mol Ther 9: 209-217; doi:10.1016/j.ymthe.2003.11.021

Ablating CAR and Integrin Binding in Adenovirus Vectors Reduces Nontarget Organ Transduction and Permits Sustained Bloodstream Persistence Following Intraperitoneal Administration

Masaki Akiyama, Stephen Thorne, David Kirn, Peter W. Roelvink, David A. Einfeld, C. Richter King and Thomas J. Wickham

Mol Ther 9: 218-230; doi:10.1016/j.ymthe.2003.10.010

AAV2 Vector Harboring a Liver-Restricted Promoter Facilitates Sustained Expression of Therapeutic Levels of alpha-Galactosidase A and the Induction of Immune Tolerance in Fabry Mice

Robin J. Ziegler, Scott M. Lonning, Donna Armentano, Chester Li, David W. Souza, Maribeth Cherry, Christine Ford, Christine M. Barbon, Robert J. Desnick, Guangping Gao, James M. Wilson, Richard Peluso, Simon Godwin, Barrie J. Carter, Richard J. Gregory, Samuel C. Wadsworth and Seng H. Cheng

Mol Ther 9: 231-240; doi:10.1016/j.ymthe.2003.11.015

Contribution of Toll-like Receptor 9 Signaling to the Acute Inflammatory Response to Nonviral Vectors

Hongmei Zhao, Hiraoki Hemmi, Shizuo Akira, Seng H. Cheng, Ronald K. Scheule and Nelson S. Yew

Mol Ther 9: 241-248; doi:10.1016/j.ymthe.2003.11.012

CpG Methylation of a Plasmid Vector Results in Extended Transgene Product Expression by Circumventing Induction of Immune Responses

A. Reyes-Sandoval and H. C. J. Ertl

Mol Ther 9: 249-261; doi:10.1016/j.ymthe.2003.11.008

The Effects of rAAV2-Mediated NGF Gene Delivery in Adult and Aged Rats

Ke Wu, Craig A. Meyers, Nicole K. Guerra, Michael A. King and Edwin M. Meyer

Mol Ther 9: 262-269; doi:10.1016/j.ymthe.2003.11.010

Nerve Growth Factor Receptor-Mediated Gene Transfer

Nan Ma, Shan Shan Wu, Yue Xia Ma, Xu Wang, Jieming Zeng, Guping Tong, Yan Huang and Shu Wang

Mol Ther 9: 270-281; doi:10.1016/j.ymthe.2003.11.005

Enhanced Gene Delivery by Avidin-Displaying Baculovirus

Jani K. Räty, Kari J. Airenne, Ari T. Marttila, Varpu Marjomäki, Vesa P. Hytönen, Pauliina Lehtolainen, Olli H. Laitinen, Anssi J. Mähönen, Markku S. Kulomaa and Seppo Ylä-Herttuala

Mol Ther 9: 282-291; doi:10.1016/j.ymthe.2003.11.004

Development of Hyperactive Sleeping Beauty Transposon Vectors by Mutational Analysis

Hatem Zayed, Zsuzsanna Izsvák, Oliver Walisko and Zoltán Ivics

Mol Ther 9: 292-304; doi:10.1016/j.ymthe.2003.11.024

Model of Unidirectional Transluminal Gene Transfer

Marco A. Arap, Johanna Lahdenranta, Amin Hajitou, Frank C. Marini III, ChristopherG. Wood, Kenneth C. Wright, Juan Fueyo, Wadih Arap and Renata Pasqualini

Mol Ther 9: 305-310; doi:10.1016/j.ymthe.2003.11.016

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