TABLE OF CONTENTS
Volume 9, Issue S1 (May 2004)
Abstracts
1. Molecular Long-Term Follow Up in Non-Human Primates That Received Retrovirally Transduced Stem Cells: Despite Proto-Oncogene Insertion No Leukemia or Hematopoietic Abnormalities
Brian C. Beard, Kirsten A. Keyser, Julie Morris, Bobbie Thomasson and Hans-Peter Kiem
Mol Ther 9: S1-S1; doi:10.1016/j.ymthe.2004.05.042
2. Promoter Trapping Reveals Significant Differences in Integration Site Selection Between MLV and HIV Vectors
Michele De Palma, Eugenio Montini, Francesca R. Santoni de Sio, Alessandra Gentile, Enzo Medico and Luigi Naldini
Mol Ther 9: S1-S1; doi:10.1016/j.ymthe.2004.05.043
3. Effect of Retroviral and Lentiviral Vector Integrations on Transcription of Flanking Genes
Eugenio Montini, Daniela Cesana and Luigi Naldini
Mol Ther 9: S1-S2; doi:10.1016/j.ymthe.2004.05.084
4. In Vitro and In Vivo Analysis of Feline Immunodeficiency Virus-Based Lentiviral Vector Integration
Yubin Kang, Todd E. Scheetz, Christopher J. Moressi, Diane Thi Tran, Litao Xie, Beverly L. Davidson, Thomas L. Casavant and Paul B. McCray Jr
Mol Ther 9: S2-S2; doi:10.1016/j.ymthe.2004.05.086
5. Evaluation of the Genotoxic Potential of a Self-Inactivating |[gamma]|-Globin Lentiviral Vector
Phillip W. Hargrove, Hideki Hanawa, Steven Kepes, Cheng Cheng, Geoffrey Neale, Arthur W. Nienhuis and Derek A. Persons
Mol Ther 9: S2-S3; doi:10.1016/j.ymthe.2004.05.087
6. Investigations into the Relative Safety of Lentiviral Vectors to Oncoretroviral Vectors
Xiaobin Lu, Ziping Chen, Rene Molina, Poorna Ramamurthy, Gwendolyn K. Binder and Boro Dropulic
Mol Ther 9: S3-S3; doi:10.1016/j.ymthe.2004.05.085
7. The Risk of Integration: Cell Lines for Determining the Frequency and Character of Vector-Mediated Insertional Gene Activation
Andrea D. Converse, Nikunj V. Somia and R. Scott McIvor
Mol Ther 9: S3-S3; doi:10.1016/j.ymthe.2004.05.088
8. Integrated Self-Inactivating Lentiviral Vectors Produce Full-Length Genomic Transcripts Competent for Encapsidation and Integration
Aaron C. Logan, Dennis L. Haas, Tal Kafri and Donald B. Kohn
Mol Ther 9: S4-S4; doi:10.1016/j.ymthe.2004.05.089
9. Mobilization of Sendai Virus Vectors (SeVV) by Phylogenetic Related Human Pathogens: Implications for Future Vector Generations
Christian Bernloehr, Sascha Bossow, Sorin Armeanu, Guy Ungerechts, Michael Gregor, Wolfgang J. Neubert, Ulrich M. Lauer and Michael Bitzer
Mol Ther 9: S4-S4; doi:10.1016/j.ymthe.2004.05.090
10. Cell Cycle-Dependent Transcription from Unintegrated Lentiviral Vector DNA Internal Promoters: Analyses with Class I Integrase Mutants
Dyana Saenz, Nils Loewen, David Leske, Kyle Howell, Jonathan Holmes, Margaret Good and Eric Poeschla
Mol Ther 9: S4-S5; doi:10.1016/j.ymthe.2004.05.091
11. Reporter Gene-Based Analysis of rAAV Genome Circularization and Recombination
Douglas M. McCarty, Vivian Choi and Richard J. Samulski
Mol Ther 9: S5-S5; doi:10.1016/j.ymthe.2004.05.092
12. A New Class of Hybrid Adeno-Associated Viral Vectors with Non-Homologous ITRs Improves Directional Recombination and Dual-Vector Reconstitution of Large Transgenes
Ziying Yan, Roman Zak, Yulong Zhang and John F. Engelhardt
Mol Ther 9: S5-S6; doi:10.1016/j.ymthe.2004.05.093
13. Hot Spots for rAAV2 Vector Integration in Mice
Hiroyuki Nakai, Xiaolin Wu, Sally Fuess, Theresa Storm, Shawn Burgess, Markus Grompe and Mark A. Kay
Mol Ther 9: S6-S6; doi:10.1016/j.ymthe.2004.05.094
14. Absence of T-Shaped Structure and Deletions of B and C Hairpins Have Minimal Effects on Essential Functions of AAV Inverted Terminal Repeats
Xiaodong Zhu, Juan Li and Xiao Xiao
Mol Ther 9: S6-S6; doi:10.1016/j.ymthe.2004.05.095
15. Trans-Splicing Adeno-Associated Viral Vector-Mediated Gene Therapy Is Limited by Transcription across the ITR Junction but Not by Dual Vector Co-Infection Efficiency
Zhuping Xu, Yongping Yue, Chaoyang Ye, Jianming Qiu, David J. Pintel and Dongsheng Duan
Mol Ther 9: S6-S7; doi:10.1016/j.ymthe.2004.05.096
16. Visualization of the Foci of Recombinant AAV Replication and Their Relationship with Cellular Proteins Involved in the Recognition and Repair of Double-Stranded DNA Breaks
Tiziana Cervelli, Lorena Zentilin, Alessandro Marcello and Mauro Giacca
Mol Ther 9: S7-S7; doi:10.1016/j.ymthe.2004.05.097
17. Role of Vp2 in AAV Packaging
Joshua C. Grieger, Joseph E. Rabinowitz, Dawn E. Bowles and Richard J. Samulski
Mol Ther 9: S7-S7; doi:10.1016/j.ymthe.2004.05.098
18. Incorporation of the Green Fluorescent Protein into the Adeno-Associated Virus Type 2 Capsid
Kerstin Lux, Nico Goerlitz, Kristin Leike, Daniela Goldnau, Stefan Finke, Michael Hallek and Hildegard Buening
Mol Ther 9: S8-S8; doi:10.1016/j.ymthe.2004.05.099
19. The Transcapsidation of AAV Serotypes
Joseph E. Rabinowitz, Dawn E. Bowles, Susan M. Faust, Julie G. Ledford, Scott E. Cunningham and R. Jude Samulski
Mol Ther 9: S8-S8; doi:10.1016/j.ymthe.2004.05.100
20. Directed Evolution of AAV2 Yields Novel Capsid Variants
Narendra Maheshri, Brian Kaspar and David V. Schaffer
Mol Ther 9: S8-S8; doi:10.1016/j.ymthe.2004.05.101
21. Induction of CEA in Pulmonary Vasculature to Study Targeting Strategies for Cancer
Maaike Everts, Sang Ae Kim-Park, Long P. Le, Paul N. Reynolds, William E. Grizzle and David T. Curiel
Mol Ther 9: S9-S9; doi:10.1016/j.ymthe.2004.05.044
22. Tumor Homing of Genetically Modified Bone Marrow Cells
Zong-Yi Li, Shaoheng Ni, Tobias Neff, Dmitry Shayakhmetovvv and Andre Lieber
Mol Ther 9: S9-S9; doi:10.1016/j.ymthe.2004.05.045
23. T Cell Carriers for Gene Delivery to Tumors
Caroline Cole, Rosa M. Diaz, Michael Forshaw, Timothy Kottke, Jill Thompson, Michael Gough, Xandra Breakefield, Miguel Sena-Esteves, Jian Qiao and Richard G. Vile
Mol Ther 9: S9-S10; doi:10.1016/j.ymthe.2004.05.046
24. Antibody-Targeted Fusion Provides a Versatile Platform for Novel Targeted Therapies
Takafumi Nakamura, Kah-Whye Peng, Sompong Vongpunsawad, Mary Harvey, Hiroyuki Mizuguchi, Takao Hayakawa, Roberto Cattaneo and Stephen J. Russell
Mol Ther 9: S10-S10; doi:10.1016/j.ymthe.2004.05.047
25. Molecular Imaging-Guided Gene Therapy of Experimental Gliomas
Maria A. Rueger, Alexandra Winkeler, Lisa Li, Benedikt Rueckriem, Stefan Vollmar, Wolf D. Heiss and Andreas H. Jacobs
Mol Ther 9: S10-S11; doi:10.1016/j.ymthe.2004.05.048
26. Tropism Illustrated: How a Morbillivirus Takes Over the Immune System
von Messling Veronika, Milosevic Dragana and Cattaneo Roberto
Mol Ther 9: S11-S11; doi:10.1016/j.ymthe.2004.05.049
27. Differential Phage Display for Discovery of Nuclear Localization Peptides: Application to Mammary Adenocarcinoma
Ashley A. Weiner and Todd D. Giorgio
Mol Ther 9: S11-S12; doi:10.1016/j.ymthe.2004.05.050
28. A clinically relevant ex vivo toxicity assay using human liver slices to determine specificity of oncolytic viruses
Marianne G. Rots, Marieke GL Elferink, Dorenda Oosterhuis, Peter Olinga, David T. Curiel, Hidde J. Haisma and Geny M. M. Groothuis
Mol Ther 9: S12-S12; doi:10.1016/j.ymthe.2004.05.051
29. In Vivo Imaging and Therapy of Breast Cancer Xenografts Following MUC1 Promoter-Driven Expression of the Sodium Iodide Symporter (NIS)
Roisin M. Dwyer, Elizabeth R. Bergert, Michael K. O'Connor, Sandra J. Gendler and John C. Morris
Mol Ther 9: S12-S12; doi:10.1016/j.ymthe.2004.05.052
30. Patient Oriented DNA Based Therapy from the Bench to the Patient
Patricia Ohana, Ofer Gofrit, Basem Ayesh, Imad Matouk, Tatiana Birman, Suhail Ayesh, Aya Mizrahi, Ami Sidi, Tamar Schneider, Nathan de Groot and Abraham Hochberg
Mol Ther 9: S13-S13; doi:10.1016/j.ymthe.2004.05.053
31. Creation of a Hemophilia B Mouse Expressing Defective Human Factor IX
Paul E. Monahan, Tai-Ping Zhang, Da-Yun Jin, Tong Gui and Darrel W. Stafford
Mol Ther 9: S13-S13; doi:10.1016/j.ymthe.2004.05.054
32. Efficacy and Safety of Mouse Coagulation Factor VIIa Gene Transfer in Hemophilia B Mice
Majed N. Aljamali, Paris Margaritis, Valder R. Arruda, Alexander Schlachterman, Rodney M. Camire and Katherine A. High
Mol Ther 9: S14-S14; doi:10.1016/j.ymthe.2004.05.055
33. Induction of Antigen-Specific T Cell Anergy and Deletion by Hepatic AAV Gene Transfer
Eric Dobrzynski, Lixin Wang, Ou Cao, Federico Mingozzi and Roland W. Herzog
Mol Ther 9: S14-S14; doi:10.1016/j.ymthe.2004.05.056
34. Retroviral Vector-Mediated Neonatal Gene Therapy Results in Long-Term and Therapeutic Levels of Canine Factor VIII Expression in Hemophilia A Mice and Dogs
Lingfei Xu, Timothy C. Nichols, Rita Sarkar, Stephanie McCorquodale, Dwight Bellinger and Katherine P. Ponder
Mol Ther 9: S14-S15; doi:10.1016/j.ymthe.2004.05.057
35. Downregulation of Immune Responses Induced by Oral DNA Administration
Andrew Gomez Vargas and Gonzalo Hortelano
Mol Ther 9: S15-S15; doi:10.1016/j.ymthe.2004.05.058
36. Permanent Phenotypic Correction of Haemophilia B in Immunocompetent Mice by Prenatal Gene Therapy
Simon N. Waddington, Megha S. Nivsarkar, Ajay R. Mistry, Suzanne M. K. Buckley, Geoffrey Kemball-Cook, Karen L. Mosley, Kyriacos Mitrophanous, Pippa Radcliffe, Maxine V. Holder, Mairi Brittan, Tassos Georgiadis, Faisal Al-Allaf, Brian W. Bigger, Lisa G. Gregory, Terence H. Cook, Robin R. Ali, Adrian Thrasher, Edward G. D. Tuddenham, Mike Themis and Charles Coutelle
Mol Ther 9: S15-S15; doi:10.1016/j.ymthe.2004.05.059
37. Duration of Immunologically Detectable AAV-2 Capsid in an Animal Model
Denise E. Sabatino, Federico Mingozzi, David C. Brooks, Alex Schlachterman, Shyrie Edmonson, Linda Couto, Peter Colosi, Haifeng Chen, Hildegund C. J. Ertl and Katherine A. High
Mol Ther 9: S16-S16; doi:10.1016/j.ymthe.2004.05.060
38. AAV-mediated gene therapy for systemic lupus erythematosus (SLE)
Xiaojing Ye, Tong Zhu, Juan Li and Xiao Xiao
Mol Ther 9: S16-S16; doi:10.1016/j.ymthe.2004.05.061
39. Reversal of Diabetes by Inducing Islet Neogenesis Using Helper Dependent Adenovirus Mediated Gene Therapy
Vijay Yechoor, Hideto Kojima, Mineko Fujimiya, Bonne Thompson, Benny Chang, Laura Nelly, Philip Ng and Lawrence Chan
Mol Ther 9: S16-S17; doi:10.1016/j.ymthe.2004.05.062
40. Correction of Dyslipidemia in Murine and Feline Models of Lipoprotein Lipase Deficiency by Intramuscular Administration of AAV1-LPLS447X
Colin J. D. Ross, Jaap Twisk, Jan Albert Kuivenhoven, Guoqing Liu, Fudan Miao, Karen van den Oever, Maarten Beetz, Dennis Verbart, Andrew Bakker, Paul P. A. Oranje, Wim T. Hermens, Paul Dijkhuizen, John J. P. Kastelein, Janneke J. M. Meulenberg and Michael R. Hayden
Mol Ther 9: S17-S17; doi:10.1016/j.ymthe.2004.05.063
41. Ex Vivo Gene Therapy Provides a Unique Therapeutic Benefit and Corrects Metachromatic (MLD) and Globoid (GLD) Leukodystrophy in the Mouse Models
Alessandra Biffi, Ilaria Visigalli, Angelo Quattrini, Ilaria Bertani, Michele De Palma, Ubaldo Del Carro, Riccardo Brambilla, Sergio Marchesini, Claudio Bordignon and Luigi Naldini
Mol Ther 9: S17-S18; doi:10.1016/j.ymthe.2004.05.064
42. AAV-mediated gene therapy causes functional improvements in a murine model of infantile neuronal ceroid lipofuscinosis (INCL, Batten Disease)
M. Griffey, D. Wozniak, M. Wong, S. Rothman, E. Bible, J. Cooper, C. Vogler and M. Sands
Mol Ther 9: S18-S18; doi:10.1016/j.ymthe.2004.05.065
43. Immunological Response Characterization in an Alzheimer's Disease Mouse Model Following HSV Amplicon-Based A|[beta]| Vaccination
William J. Bowers, Michael A. Mastrangelo, Hilary A. Stanley, Ya-Hui Chiu and Howard J. Federoff
Mol Ther 9: S18-S18; doi:10.1016/j.ymthe.2004.05.068
44. AAV Retrograde Transport Potential and Therapeutic Approaches for ALS
Brian K. Kaspar, Jeronia Vich, Lindsey Christian, Jeffrey D. Rothsten and Fred H. Gage
Mol Ther 9: S18-S19; doi:10.1016/j.ymthe.2004.05.066
45. Adenoviral tetanus toxin light chain gene expression in the brainstem induces specific motor inhibition
Ajit A. Krishnaney, Zuowei Zhao, Qingshang Teng, James Liu, Diana Tenase, Mary Garrity-Moses, Michael Davis and Nicholas M. Boulis
Mol Ther 9: S19-S19; doi:10.1016/j.ymthe.2004.05.067
46. Clinical and Functional Recovery from Experimental Autoimmune Encephalomyelitis by Intracisternal Delivery of IL4 from a Helper-Dependent Adenoviral Vector. A Pre-Clinical Model of Gene Therapy of Multiple Sclerosis
Erica Butti, Alessandra Recchia, Alessandra Bergami, Anna Stornaiuolo, Elena Brambilla, Roberto Furlan, Gianvito Martino and Fulvio Mavilio
Mol Ther 9: S19-S20; doi:10.1016/j.ymthe.2004.05.069
47. Cytokine gene-modified mesenchymal stem cells promote functional recovery and reduce infarct size in the rat middle cerebral artery occlusion model
Kazuhiko Kurozumi, Kiminori Nakamura, Tomotsugu Ichikawa, Yasuhiro Ono, Takashi Tamiya, Yoshinori Ito, Osamu Honmou, Kiyohiro Houkin, Hirofumi Hamada and Isao Date
Mol Ther 9: S20-S20; doi:10.1016/j.ymthe.2004.05.070
48. In vivo and in situ delivery of huntingtin-specific single-chain Fv intrabody genes as therapeutic agents for Huntington's disease
Todd W. Miller, William J. Wolfgang, Kevin Manley, Yangsheng Zhou, Chun Zhou, Jack M. Webster, Nicholas D. Mazarakis and Anne Messer
Mol Ther 9: S20-S21; doi:10.1016/j.ymthe.2004.05.071
49. AAV Vector-Mediated Gene Delivery of Aromatic L-Amino Acid Decarboxylase Restored L-DOPA Efficacy in a Primate Bilateral Model of Parkinson's Disease
Shin-ichi Muramatsu, Fumiko Ono, Yuko Nara, Mika Kodera, Naomi Takino, Junko Tsuchida, Katsuyoshi Kawasaki, Kunihiko Ikeguchi, Kenichi Fujimoto, Hideo Tsukada, Keiji Terao, Imaharu Nakano and Keiya Ozawa
Mol Ther 9: S21-S21; doi:10.1016/j.ymthe.2004.05.072
50. AAV-Mediated Expression and Secretion of ADNF-9 Protects Substantia Nigra Neurons from 6-OHDA Damage
Sophia Papadeas, George R. Breese and Thomas J. McCown
Mol Ther 9: S21-S21; doi:10.1016/j.ymthe.2004.05.073
51. A Novel Approach to Stem Cell Gene Therapy: Controlling Stem Cell ifferentiation with Engineered Zinc-Finger Protein Transcription Factors
Victor V. Bartsevich, Jeffrey C. Miller, Casey C. Case and Carl O. Pabo
Mol Ther 9: S21-S22; doi:10.1016/j.ymthe.2004.05.074
52. Gut Enriched Kruppel-Like Factor (GKLF) Inhibits Differentiation and Induces Self-Renewal of Murine Embryonic Stem Cells
Rebecca J. Chan, Yanjun Li, Li Zhong and Mervin C. Yoder
Mol Ther 9: S22-S22; doi:10.1016/j.ymthe.2004.05.075
53. Inducable FGFr-1 stimulates self renewal of hematopoietic cells
Michael A. Weinreich and C. Anthony Blau
Mol Ther 9: S22-S22; doi:10.1016/j.ymthe.2004.05.078
54. Restriction of Transgene Expression to the B-Lymphoid Progeny of Human Lentivirally Transduced CD34+ Cells
Thomas Moreau, Florence Bardin, Jean Imbert, Christian Chabannon and Cecile Tonnelle
Mol Ther 9: S23-S23; doi:10.1016/j.ymthe.2004.05.076
55. Alteration of Primitive Hematopoietic Cell Fate and Growth by the GATA-2 Transcription Factor
Stacy L. Throm and Derek A. Persons
Mol Ther 9: S23-S23; doi:10.1016/j.ymthe.2004.05.077
56. Intraplacental Gene Transfer of IGF-1 Corrects Intrauterine rowth Restriction in the Rabbit Model
Sundeep G. Keswani, Anna B. Katz, Elliot B. Kozin, Phillip W. Zoltic and Timothy M. Cromblehome
Mol Ther 9: S24-S24; doi:10.1016/j.ymthe.2004.05.037
57. Persistent PEDF Expression Following Intravitreal Administration of High-Capacity Adenovectors
Joseph T. Bruder, Ping Chen, Kurt Kroeger, Melissa Hamilton, Miguel Carrion, Douglas E. Brough, Lisa L. Wei, C. Richter King, Peter A. Campochiaro and Peter Gehlbach
Mol Ther 9: S24-S24; doi:10.1016/j.ymthe.2004.05.038
58. Toward Adenoviral Mediated RNA Interference for the Treatment of Hepatitis B Virus Infection
Anton P. McCaffrey, Kusum Pandey, Anja Ehrhardt, Zan Huang and Mark A. Kay
Mol Ther 9: S24-S25; doi:10.1016/j.ymthe.2004.05.039
59. Development of Conditionally Replicative Adenoviruses as Platforms for the Expression of shRNAs or Therapeutic Genes
Jan E. Carette, Frederik H. E. Schagen, Ren|[eacute]|e M. Overmeer, Jeroen D.C. Mastenbroek, Winald R. Gerritsen and Victor W. van Beusechem
Mol Ther 9: S25-S25; doi:10.1016/j.ymthe.2004.05.040
60. Site-specific integration in human somatic cell DNA by adeno/AAV hybrid vectors
Alessandra Recchia, Laura Perani, Daniela Sartori, Clelia Olgiati and Fulvio Mavilio
Mol Ther 9: S25-S26; doi:10.1016/j.ymthe.2004.05.041
61. Prevention of liver cirrhosis development in rats with recombinant SV40 vectors expressing IGF-I
Maria Vera, Laura Martinez, Mikel Zaratiegui, Carlos M. Rodriguez, Jesus Prieto and Puri Fortes
Mol Ther 9: S26-S26; doi:10.1016/j.ymthe.2004.05.080
62. Ras Signaling as a Marker for Application of Oncolytic Herpes Mutant Against Lymphoma
Faris Farassati, Natasha Atanaskova, Corey Raffel, Patrick Johnston and Patrick Lee
Mol Ther 9: S26-S26; doi:10.1016/j.ymthe.2004.05.079
63. Re-directed herpes simplex virus infection by a soluble, bi-specific adapter protein for gD in combination with nectin-1 blocking agents
Kenji Nakano, Ryutaro Asano, Kohei Tsumoto, William F. Goin, Izumi Kumagai, Justus B. Cohen and Joseph C. Glorioso
Mol Ther 9: S26-S26; doi:10.1016/j.ymthe.2004.05.081
64. Bioluminescence Imaging of Regulated Gene Expression Using HSV-1 Amplicon Vectors in Rodent Brain
Sam Wang, Jeremy Petravicz and Xandra O. Breakefield
Mol Ther 9: S27-S27; doi:10.1016/j.ymthe.2004.05.082
65. Systemic Cancer Therapy with an Enhanced Tumor-Selective Vaccinia Virus Lacking Anti-Apoptosis Viral Genes Spi-2 and Spi-1
Zongsheng Guo, Arpana Naik, Yun Hu, Richard DeMarco, Mark O'Malley, Richard Alexander, Bernard Moss, Mike Lotze and David L. Bartlett
Mol Ther 9: S27-S27; doi:10.1016/j.ymthe.2004.05.083
66. A safe and efficient lentiviral vector system: optimisation of virus production and purification
Donald S. Anson
Mol Ther 9: S27-S27; doi:10.1016/j.ymthe.2004.06.001
67. Bovine Immunodeficiency Virus Based Lentiviral Vector with Improved Safety Features
Rene P. Molina, Hongqing Q. Ye, James Brady, Jingli Zhang, Heather Zimmerman, Michael Kaleko and Tianci Luo
Mol Ther 9: S28-S28; doi:10.1016/j.ymthe.2004.06.002
68. Improved lentiviral vector system with enhanced safety features
Jill Oldenburg, Aaron C. Logan, Maria Barcova, Celina Ngiam and Paula M. Cannon
Mol Ther 9: S28-S28; doi:10.1016/j.ymthe.2004.06.003
69. Closing-in on the titer gap between transient transfection and packaging cell lines
Adam S. Cockrell, Kailing Fu, Hong Ma, Thomas McCown and Tal Kafri
Mol Ther 9: S28-S28; doi:10.1016/j.ymthe.2004.06.004
70. Stable packaging cell lines development for the production of lentiviral vectors
Sophie Broussau, Nadine Jabbour, Guillaume Lachapelle, Yan Xu, Alaka Mullick, Renald Gilbert and Bernard Massie
Mol Ther 9: S29-S29; doi:10.1016/j.ymthe.2004.06.005
71. Chimeric lentiviral vectors derived from HIV-1 and HIV-2
Suresh K. Arya, Jenice D'Costa, Geetanjali Sachdeva, Jean Cho and Kritika Kachapati
Mol Ther 9: S29-S29; doi:10.1016/j.ymthe.2004.06.006
72. Position and Copy Number Dependence of the Central Polypurine Tract (cPPT) Function in Simple and Complex Lentiviral Vectors
Alex H. Chang, Leszek Lisowski, Matthias Stephan, Isabelle Rivi|[egrave]|re and Michel Sadelain
Mol Ther 9: S29-S30; doi:10.1016/j.ymthe.2004.06.007
73. An inhibitory effect of a sequence just upstream of the central polypurine tract of HIV-1 on RNA production of an HIV-1-based vector
Ryuta Sakuma, Aikichi Iwamoto and Yoshihiro Kitamura
Mol Ther 9: S30-S30; doi:10.1016/j.ymthe.2004.06.008
74. Factors affecting long terminal repeat (LTR)-driven gene expression using VL30 retro-vectors and DNA plasmid vectors
Jim Williams, Jeremy Luke and Clague Hodgson
Mol Ther 9: S30-S30; doi:10.1016/j.ymthe.2004.06.009
75. The Optimization of a Single-LTR HIV-1 Vectors for Functional Genomic Applications
Hong Ma and Tal Kafri
Mol Ther 9: S30-S31; doi:10.1016/j.ymthe.2004.06.010
76. Development of multigene lentiviral vectors containing the encephalomyocarditis virus IRES and foot-and-mouth disease virus 2A cleavage factor
Dhanalakshmi Chinnasamy, Michael Milsom, James Neuenfeldt, Geoffrey P. Margison, Leslie J. Fairbairn and Nachimuthu Chinnasamy
Mol Ther 9: S31-S31; doi:10.1016/j.ymthe.2004.06.011
77. Production and Purification of Measles Virus for Oncolytic Virotherapy Clinical Trials
Kirsten K. Langfield, Troy R. Wegman, Henry J. Walker, Guy E. Griesmann, Julie A. Sauer, Sharon A. Stephan and Mark J. Federspiel
Mol Ther 9: S31-S31; doi:10.1016/j.ymthe.2004.06.012
78. Enhancement of Retroviral-Mediated Gene Transfer by Purification of Virus Stocks from Inhibitors of Transduction
Natalia Landazuri and Joseph M. Le Doux
Mol Ther 9: S32-S32; doi:10.1016/j.ymthe.2004.06.013
79. Validation of viable producer cell removal/inactivation from clinical-grade oncoretroviral vector supernatant produced in cell factories
Mark Przybylowski, Amir Hakakha, Yong Fan and Isabelle Riviere
Mol Ther 9: S32-S32; doi:10.1016/j.ymthe.2004.06.014
80. A Rapid and Effective Lentivirus Purification Procedure
Christine R. Rowley, Patrick L. Sinn, Linda Bullinga, Paul B. McCray Jr. and Beverly L. Davidson
Mol Ther 9: S32-S32; doi:10.1016/j.ymthe.2004.06.015
81. Modification of HEK 293 cell integrin expression profile allows convenient large-scale roller bottle production of lentiviral vectors
Manij Patel, David A. Wilcox, Angela M. Giddings, Tristan R. McKay and John C. Olsen
Mol Ther 9: S33-S33; doi:10.1016/j.ymthe.2004.06.016
82. Adaptation of a lentiviral vector producer cell line to reduced-serum, suspension culture for large scale production
Kay Townsend, Yong Chen, Jonathan Dayao, Deborah Farson, William M. Miller and Andy Lin
Mol Ther 9: S33-S33; doi:10.1016/j.ymthe.2004.06.017
83. Development of an RCL assay for EIAV based products
James E. Miskin, Holger Roehl, Denise Westfall, Jonathan Rohll, Daniel Chipchase, Douglas Jolly, Susan M. Kingsman and Kyriacos A. Mitrophanous
Mol Ther 9: S33-S33; doi:10.1016/j.ymthe.2004.06.018
84. Enhanced detection method for retrovirus in vaccine
Ji Young Yoo, Beom-Seok Suh, Sue Nie Park, Joo-Hang Kim and Chae-Ok Yun
Mol Ther 9: S34-S34; doi:10.1016/j.ymthe.2004.06.037
85. High-Level Expression of Wild-Type p53 from the Novel p53-Responsive pCLPG Retrovirus Halts the Proliferation of Tumor Cells Regardless of Their p53 Status
Bryan E. Strauss, Marcio C. Bajgelman and Eugenia Costanzi-Strauss
Mol Ther 9: S34-S34; doi:10.1016/j.ymthe.2004.06.019
86. Mutation Frequency of the p53 cDNA Introduced by the Retroviral Vector
Su Su, Atushi Watanabe and Takashi Shimada
Mol Ther 9: S34-S35; doi:10.1016/j.ymthe.2004.06.020
87. APOBEC3G and Immunity to retroviruses
Reuben S. Harris
Mol Ther 9: S35-S35; doi:10.1016/j.ymthe.2004.06.021
88. AAV clades: Their Ability To Recombine and Cross Species-Barriers
Luk H. Vandenberghe, Guangping Gao, Mauricio R. Alvira, Roberto Calcedo and James M. Wilson
Mol Ther 9: S35-S35; doi:10.1016/j.ymthe.2004.06.024
89. Isolation of a Close AAV5 Relative from Goat Tissues: Evidence of Host Promiscuity
Alejandra E. Arbetman, Michael A. Lochrie, Britta Randlev, Richard T. Surosky, Shangzhen Zhou, Jennifer Wellman, Cheryl Pater, Howard Lehmkuhl, Lea Ann Hobbs, Glenn Pierce and Peter Colosi
Mol Ther 9: S35-S36; doi:10.1016/j.ymthe.2004.06.038
90. Evaluation of Novel Gene Transfer Vectors Derived from Infectious Molecular Clones of Primate AAVs
Xiaoyang Zhou, Guangping Gao, Roland A. Owens, Roberto Calcedo and James M. Wilson
Mol Ther 9: S36-S36; doi:10.1016/j.ymthe.2004.06.025
91. Universal purification of AAV serotypes 1|[ndash]|5 modified to contain a heparin binding epitope
Susan M. Faust, Dawn E. Bowles, Scott E. Cunningham, Joseph E. Rabinowitz and R. Jude Samulski
Mol Ther 9: S36-S36; doi:10.1016/j.ymthe.2004.06.026
92. Metabolically Biotinylated Adeno-Associated Virus (AAV) Types 1, 2, 3, 4 and 5 for Scalable Purification and Vector Retargeting
A. Kate Sasser, Gregory S. Arnold and Jeffrey S. Bartlett
Mol Ther 9: S37-S37; doi:10.1016/j.ymthe.2004.06.027
93. Targeting AAV to Brain Vascular Endothelium
Yong Hong Chen and Beverly L. Davidson
Mol Ther 9: S37-S37; doi:10.1016/j.ymthe.2004.06.028
94. Targeting Endothelial Cells in Mice with Adeno-Associated Virus Serotype 1 Vector
Haiyan Fu, Joseph Muenzer, Richard J. Samulski, Kang Lu, Jerillyn S. Jennings and Douglas M. McCarty
Mol Ther 9: S37-S38; doi:10.1016/j.ymthe.2004.06.029
95. Retargeting AAV-2 to Angiogenic Endothelial Cells with Tumor Vasculature Specific Capsid Variants
Andreas Riederer, Bernard Kaess, Luca Perabo, Hildegard Buening and Michael Hallek
Mol Ther 9: S38-S38; doi:10.1016/j.ymthe.2004.06.030
96. Transgene Expression from Recombinant AAV-8 Vectors in the Liver Occurs Independently of the Serotype Origin of the Viral Inverted Terminal Repeats
Dirk Grimm, Hiroyuki Nakai, Theresa A. Storm, Efren P. Riu and Mark A. Kay
Mol Ther 9: S38-S38; doi:10.1016/j.ymthe.2004.06.031
97. Selection of Potent AAV Pseudotypes To Transduce Rat Pancreatic Islets
Brigitte Le Mauff, Fran|[ccedil]|oise Boeffard, Nasro Benrezzak and Ignacio Anegon
Mol Ther 9: S38-S39; doi:10.1016/j.ymthe.2004.06.032
98. Adeno-Associated Virus SerOtype 8 as a Vector for HEPATIC Delivery of alpha-1 Anti-Trypsin (AAT)
Thomas J. Conlon, Travis L. Cossette and Terence R. Flotte
Mol Ther 9: S39-S39; doi:10.1016/j.ymthe.2004.06.033
99. Long-term Expression of Soluble TNFR:Fc Protein Following Multiple Administrations of AAV-TNFR:Fc Vector Pseudotyped with Capsids of Alternate Serotypes
Ziv Sandalon, Kurt Lustig and Haim Burstein
Mol Ther 9: S39-S39; doi:10.1016/j.ymthe.2004.06.034
100. An Evaluation of the Use of Adeno-Associated Virus Serotypes AAV1 and AAV8 To Obtain Stable Therapeutic Levels of Apolipoprotein A-I in Mouse Plasma
Karen F. Kozarsky, Deborah A. Welham and Mary H. Donahee
Mol Ther 9: S39-S40; doi:10.1016/j.ymthe.2004.06.035
101. Toxicology and Biodistribution Studies of a Recombinant Adeno-Associated Virus 2 (rAAV2) Alpha-1 Antitrypsin (AAT) Vector
Amy E. Poirier, Lynn A. Combee, Ashley T. Martino and Terence R. Flotte
Mol Ther 9: S40-S40; doi:10.1016/j.ymthe.2004.06.036
102. Catheter-Based Intrahepatic rAAV Gene Delivery: Influence of Infusion Flow Rate and Volume on Uptake
Lin He, Dea Nagy, Joe Vargas, Tongyao Liu, Ciaran Scallan, Shangzhen Zhou, Sharmila Vijay, Jurg Sommer, Kirk W. Johnson, Linda B. Couto, Pierce F. Glenn and Bin Yang
Mol Ther 9: S40-S40; doi:10.1016/j.ymthe.2004.06.039
103. Comparison of the Efficacy on Gene Transfer by AAV Vectors Delivered by Distinct Routes of Administration to the Liver of Hemophilia B Dogs
Valder Arruda, Ciaran Scallan, Haiyan Jiang, Linda Couto, Roland W. Herzog, Timothy Nichols, Glenn Pierce and Katherine A. High
Mol Ther 9: S40-S41; doi:10.1016/j.ymthe.2004.06.040
104. A novel Deletion in the FVIII B-Domain That Reduces Transgene Size While Preserving FVIII Activity
Yi-Lin Liu, Hua Zhu, Alexander Schlachterman, Heesoon Chang, Rodney M. Carime and Katherine A. High
Mol Ther 9: S41-S41; doi:10.1016/j.ymthe.2004.06.041
105. Optimization of Short-Hairpin RNAs for the Treatment of the Hepatitis C Virus Using AAV Vectors with Multiple Expression Cassettes
Peter W. Roelvink, David A. Suhy, Alexander A. Kolykhalov, Sara M. Cunningham, Taka Mizutani and Mark A. Kay
Mol Ther 9: S41-S41; doi:10.1016/j.ymthe.2004.06.042
106. Functional Human alpha 1 Antitrypsin Secreted from Muscle Transduced by Adeno-Associated Virus (rAAV1) Vector
Yuanqing Lu, Martha Compbell-Yhompason, Chengwen Li, Terence R. Flotte and Sihong Song
Mol Ther 9: S41-S42; doi:10.1016/j.ymthe.2004.06.043
107. Use of Adeno-Associated Viral Vectors for Effective Delivery of Engineered Zinc Finger Protein Transcription Factors
Yuxin Liang, Linda Hinh, Steve Zhang, Lei Zhang, Deng-Feng Xia, Kristine Venstrom, S. Kaye Spratt, Edward Rebar and Casey Case
Mol Ther 9: S42-S42; doi:10.1016/j.ymthe.2004.06.044
108. In Vitro Down-Regulation of Transgene Expression with Cre/loxP Mediated Recombination
J. Lawrence Merritt II, Jan Daniels and David B. Schowalter
Mol Ther 9: S42-S42; doi:10.1016/j.ymthe.2004.06.045
109. Cyclical Mechanical Stretch and AAV2 Mediated Gene Transfer to Cultured Human Vascular Cells
Sabyasachi Sen, Jeff S. Bartlett, Yvonne Birney, Paul Cahill and Timothy O'Brien
Mol Ther 9: S42-S42; doi:10.1016/j.ymthe.2004.06.046
110. Helper-Dependent Adenovirus with the Cytokeratin-18 Promoter Produces Greater Transepithelial Chloride Current and More Persistent Transgene Expression Than the CMV Promoter in Differentiated Human Airway Epithelia
Sara L. Farmen, Philip H. Karp, Philip Ng, David R. Koehler, Jim Hu, Joseph Zabner and Michael J. Welsh
Mol Ther 9: S42-S43; doi:10.1016/j.ymthe.2004.06.047
111. A chimeric Adenovirus Vector Encoding Reovirus Attachment Protein sigma 1 Targets Cells Expressing Junctional Adhesion Molecule 1 and Sialic acid
George T. Mercier, Jacquelyn A. Campbell, James D. Chappell, Terence S. Dermody, Thilo Stehle and Michael A. Barry
Mol Ther 9: S43-S43; doi:10.1016/j.ymthe.2004.06.048
112. Gene Transfer into a Hematopoietic Cell Line Using a Helper-Dependent Adenoviral Vector with the Chimeric Ad5/35 Fiber
Michael A. Balamotis, Katie Huang and Ko Mitani
Mol Ther 9: S43-S43; doi:10.1016/j.ymthe.2004.06.049
113. Role of CD46 on Ad35 Vector-Mediated Transduction
Fuminori Sakurai, Hiroyuki Mizuguchi, Kenji Kawabata, Naokazu Inoue, Masaru Okabe, Teruhide Yamaguchi and Takao Hayakawa
Mol Ther 9: S44-S44; doi:10.1016/j.ymthe.2004.06.050
114. Adenoviral Vectors for Gene Therapy with Improved Entry of Malignant Glioma
Eric Brouwer, Olga J. Ophorst, Menzo J. E. Havenga, Bertie H. C. G. M. de Leeuw, Rob C. Hoeben and Peter A. E. Sillevis Smitt
Mol Ther 9: S44-S44; doi:10.1016/j.ymthe.2004.06.051
115. Genetic Fiber Mosaic Adenovirus Confers New Properties to Adenoviral Particles
Larisa Pereboeva, Svetlana Komarova and David T. Curiel
Mol Ther 9: S44-S45; doi:10.1016/j.ymthe.2004.06.052
116. Members of Adenovirus Subgroup B Utilize CD80 (B7.1) and CD86 (B7.2) as Primary Cellular Attachment Receptors
Joshua J. Short, Alexander V. Pereboev, Yosuke Kawakami, Chenthamarakshan Vasu, Mark J. Holterman and David T. Curiel
Mol Ther 9: S45-S45; doi:10.1016/j.ymthe.2004.06.082
117. Antitumor Immunity Induced by Adenovirus Vector-Mediated Transduction of OX40 Ligand
Toshiaki Kikuchi, Sita Andarini and Toshihiro Nukiwa
Mol Ther 9: S45-S45; doi:10.1016/j.ymthe.2004.06.055
118. Efficient Infection of Head and Neck Cancer Cells by Ad5/35 Hybrid Virus
Elina Suominen, Reidar Grenman and Mikko Savontaus
Mol Ther 9: S46-S46; doi:10.1016/j.ymthe.2004.06.056
119. Studies on the Targeting of Adenoviral Vectors Carrying a Tumor-Cell Specific Peptide
Karola Rittner, Valerie Schreiber, Klaus Schughart, Nicolas Futin, Catherine Ledoux and Monika Lusky
Mol Ther 9: S46-S46; doi:10.1016/j.ymthe.2004.06.059
120. Transient Saturation of the Reticuloendothelial System by Non-Cytotoxic Liposomes Increases Hepatocyte Transduction After Adenoviral Gene Transfer
Jan Snoeys, Geertrui Mertens, Joke Lievens, D|[eacute]|sir|[eacute]| Collen, Eric Biessen and Bart De Geest
Mol Ther 9: S47-S47; doi:10.1016/j.ymthe.2004.06.061
121. Specific Targeting of Adenoviral Vectors Using the Reovirus Attachment Protein
Frederik H. E. Schagen, Jan E. Carette, Terence S. Dermody, Winald R. Gerritsen and Victor W. van Beusechem
Mol Ther 9: S47-S47; doi:10.1016/j.ymthe.2004.06.062
122. Expression of hCD40 in the Pulmonary Endothelium Targeted Via a Fiber-Modified Adenovirus Improves Gene Delivery to the Lung
Miiru Izumi, Yosuke Kawakami, Joel N. Glasgow, Natalya Belousova and David T. Curiel
Mol Ther 9: S47-S48; doi:10.1016/j.ymthe.2004.06.063
123. Adenovirus Type 11 Based Vectors as a Platform for Treatment of Metastatic and Hematopoietic Disease
Daniel Stone and Andre Lieber
Mol Ther 9: S48-S48; doi:10.1016/j.ymthe.2004.06.064
124. Efficient Transduction and Activation of Dendritic Cells by Adenoviral Vectors Targeted to DC-SIGN
Nikolay Korokhov, Wayne A. Aldrich, Alex Krendelchtchikov, Angela Granelli-Piperno, Papia T. Banerjee, Stephen D. Gillies, Pierre L. Triozzi, Abner M. Mhashilkar and David T. Curiel
Mol Ther 9: S48-S49; doi:10.1016/j.ymthe.2004.06.065
125. Formulation and In Vitro Properties of Adenovirus-Polylactide Nanoparticle Affinity-based and Magnetic Composites
Michael Chorny, Ilia Fishbein, Ivan S. Alferiev, Origene Nyanguile and Robert J. Levy
Mol Ther 9: S49-S49; doi:10.1016/j.ymthe.2004.06.066
126. Zc-Ad Vector: A Novel Immunotargeting Vector with a Modified Fc-binding Domain
Sam C. Noureddini, Nikolay Korokhov, Abner Mhashilkar, Joanne T. Douglas and David T. Curiel
Mol Ther 9: S49-S49; doi:10.1016/j.ymthe.2004.06.067
127. Adenovirus type 5 vectors pseudotyped with fibers from subgroup D (19p and 37) show detargeting from hepatocytes in vitro and in vivo
Laura Denby, Delyth Graham, Dan J. Von Seggern, Stuart A. Nicklin and Andrew H. Baker
Mol Ther 9: S50-S50; doi:10.1016/j.ymthe.2004.06.083
128. Use of chimeric adenoviral vectors to assess capsid neutralization determinants
Soumitra Roy, David Clawson, Corinna Lebherz, Roberto Calcedo, Julio Sanmiguel, Di Wu and James M. Wilson
Mol Ther 9: S50-S50; doi:10.1016/j.ymthe.2004.06.084
129. Infectivity enhancement of an adenovirus vector via genetic incorporation of the reovirus spike protein sigma 1
Yuko Tsuruta, Larisa Pereboeva, Joel N. Glasgow, Cindy L. Luongo, Svetlana Komarova, Yosuke Kawakami and David T. Curiel
Mol Ther 9: S50-S51; doi:10.1016/j.ymthe.2004.06.085
130. Targeting of adenovirus vectors to mesothelin via a bispecific antibody reveals enhanced gene transfer to human pancreatic cancer cells
Michael A. van Geer, Ira Pastan, Victor W. van Beusechem, Hidde J. Haisma, Piter J. Bosma, Dirk J. Gouma and John G. Wesseling
Mol Ther 9: S51-S51; doi:10.1016/j.ymthe.2004.06.086
131. Cell-targeting ligand discovery using context-specific phage-presenting peptide libraries
Debadyuti Ghosh and Michael A. Barry
Mol Ther 9: S51-S51; doi:10.1016/j.ymthe.2004.06.087
132. Lentivirus-mediated expression of adenovirus fibers for the complementation or packaging of fiber gene-mutated or -deleted adenovirus vectors
Taco G. Uil, Jort Vellinga, On Ying Chan, Stephanie van der Heijdt and Rob Hoeben
Mol Ther 9: S51-S52; doi:10.1016/j.ymthe.2004.06.088
133. Enhanced expression of ABCA4 stargardt protein mediated by adenoviral vectors in a simulated ocular environment
Joshua N. Mallam, Mary Y. Hurwitz, Donna Palmer, Philip Ng and Richard L. Hurwitz
Mol Ther 9: S52-S52; doi:10.1016/j.ymthe.2004.06.089
134. Structural requirements of adenovirus targeting via by modification of minor capsid protein IX
Rob C. Hoeben, Steve J. Cramer, Leif Lindholm, Martijn J. Rabelink, Diana J. Van den Wollenberg, Stephanie Van der Heijdt and Jort Vellinga
Mol Ther 9: S52-S52; doi:10.1016/j.ymthe.2004.06.090
135. A new ligand-pseudoreceptor system for the generation of adenoviral vectors with altered tropism
Yue Zeng, Jairo Jaime, Lucie Bourget, Dreg D. Crescenzo, Maureen O'Connor and Bernard Massie
Mol Ther 9: S52-S53; doi:10.1016/j.ymthe.2004.06.091
136. Vector host interactions of group B adenoviruses in CD46 transgenic mice
Anuj Gaggar, Dmitry M. Shayakhmetov, Sonia Marwah, Shaoheng Ni and Andre M. Lieber
Mol Ther 9: S53-S53; doi:10.1016/j.ymthe.2004.06.092
137. pFex: a novel fiber exchange system for the creation of modified-fiber gene therapy vectors
Shawn E. Lupold, Wasim H. Chowdhury and Ronald Rodriguez
Mol Ther 9: S53-S53; doi:10.1016/j.ymthe.2004.06.093
138. Purification of plasmid DNA on an anion exchange column without the use of RNase to process scale
Tina M. Pitarresi, Sibylle U. Herzer, Bob Kennedy and Peter Moore
Mol Ther 9: S53-S54; doi:10.1016/j.ymthe.2004.06.493
139. Optimization of electroporation parameters for the intramuscular delivery of plasmids in pigs
Amir S. Khan, Louis C. Smith, Ronald V. Abruzzese, Kathleen K. Cummings, Melissa A. Pope, Patricia A. Brown and Ruxandra Draghia-Akli
Mol Ther 9: S54-S54; doi:10.1016/j.ymthe.2004.06.053
140. Hydrodynamics-based transfection of the liver: entrance into hepatocytes of DNA that causes expression, takes place very early after injection
Fanjam Andrianaivo, Mich|[egrave]|le Lecocq, Simone Wattiaux-De Coninck, Robert Wattiaux and Michel Jadot
Mol Ther 9: S54-S54; doi:10.1016/j.ymthe.2004.06.054
141. Development of a one-step column purification of minicircle vector DNA devoid of bacterial sequences that results in high level persistent transgene expression in vivo
Zhi-Ying Chen, Cheng-Yi He and Mark A. Kay
Mol Ther 9: S54-S55; doi:10.1016/j.ymthe.2004.06.057
142. Innovations in process technology for plasmid DNA manufacturing |[ndash]| modular variations of a generic process, regulatory relevance, and economic impact
Wayne A. Tvrdik, John Vu, Astrid Breul, Markus Mueller and Joachim Schorr
Mol Ther 9: S55-S55; doi:10.1016/j.ymthe.2004.06.058
143. Use of ciliated cell specific promoter FoxJ1 in gene transfer vectors for the airway epithelium
Anna E. Lawton, Stephanie G. Sumner-Jones, Anusha Varathalingam, Lee A. Davies, Stephen C. Hyde and Deborah R. Gill
Mol Ther 9: S55-S55; doi:10.1016/j.ymthe.2004.06.060
144. Duration of reporter gene expression from naled pDNA in the mouse lung following direct electroporation and development or wire electrodes for sheep lung electroporation studies
Ian A. Pringle, Lee L. A. Davies, Gerry McLachlan, David D. Collie, Deborah R. Gill and Stephen C. Hyde
Mol Ther 9: S56-S56; doi:10.1016/j.ymthe.2004.06.069
145. Electroporation-mediated IFN-|[beta]| gene transfer
Claire F. Evans, Maida M. de las Alas, Edward M. Nolan, Alain Luxembourg, Drew W. Hannaman, Gerald K. Nakamura, Barry L. Ellefsen and Robert M. Bernard
Mol Ther 9: S56-S56; doi:10.1016/j.ymthe.2004.06.070
146. Golden cells: gold conjugate labeling as a potential enhancer of electro-gene transfer
Feng Liu, C. E. Polley, L. B. Stiger, S. Majetich and Leaf Huang
Mol Ther 9: S56-S57; doi:10.1016/j.ymthe.2004.06.071
147. Chemical enhancers of non-viral salivary gland gene transfer
Beth M. McMahon, Yen-Ju Chen, Edmund J. Niedzinski and Michael J. Bennett
Mol Ther 9: S57-S57; doi:10.1016/j.ymthe.2004.06.068
148. The altered binding properties of sleeping beauty transposase hyperactive mutants may explain their enhanced efficacy
Julie Park, Stephen R. Yant and Mark A. Kay
Mol Ther 9: S57-S57; doi:10.1016/j.ymthe.2004.06.072
149. Anti-idiotypic CDR3 vaccination against chronic b-cell lymphoma: DNA vaccine strategy
Monica Rinaldi, Sandra Iurescia, Daniela Fioretti, Emanuela Signori, Simona Cali, Gisella Volpe, Claudia Casnici, Ornella Marelli, Giuseppe Saglio, Giancarlo Tonon and Vito Michele Fazio
Mol Ther 9: S57-S58; doi:10.1016/j.ymthe.2004.06.073
150. Cooperative strand invasion of super-coiled plasmid DNA by mixed linear PNA and PNA-peptide chimeras
Karin E. Lundin, Rongbin Ge, Mathias G. Svahn, Elisabeth Tornquist, Lars J. Branden and C. I. Edvard Smith
Mol Ther 9: S58-S58; doi:10.1016/j.ymthe.2004.06.074
151. Gene delivery in larger animals
Torunn Elisabeth Tjelle, Rune Kjeken, Ragnar Salte and Iacob Mathiesen
Mol Ther 9: S58-S58; doi:10.1016/j.ymthe.2004.06.081
152. Nucleofection and phage phiC31 integrase mediate stable introduction of a dystrophin fusion gene into muscle derived stem cell and human myoblasts
Simon P. Quenneville, Pierre Chapdelaine, Joel Rousseau, Nicolas J. Caron, Daniel Skuk, Eric C. Olivares, Michele P. Calos and Jacques P. Tremblay
Mol Ther 9: S58-S58; doi:10.1016/j.ymthe.2004.06.075
153. VEGF associated with TP to refine angiogenesis in gene therapy
Anna Rita Bellu, Marianne G. Rotz, Diane Bou|[iuml]|s, Nanno H. Mulder, Wendy Dam, Vincent van Weel, Pieter Koolwijk, Paul H. A. Quax, Hidde J. Haisma and Geke A. P. Hosper
Mol Ther 9: S58-S59; doi:10.1016/j.ymthe.2004.06.076
154. Small inhibitory RNA expressed from sleeping beauty transposons can reduce alpha1-antitrypsin expression
Kirk J. Wangensteen, Zongyu J. Chen, Clifford J. Steer and Stephen C. Ekker
Mol Ther 9: S59-S59; doi:10.1016/j.ymthe.2004.06.077
155. Non-viral gene therapy for type 1 diabetes by electrotransfer of insulin and glucokinase genes to skeletal muscle
Joel Montane, Alexandre Mas, Miquel Chillon, Xavier M. Anguela, Sergio Mu|[ntilde]|oz, Efren Riu, Pedro J. Otaegui and Fatima Bosch
Mol Ther 9: S59-S59; doi:10.1016/j.ymthe.2004.06.078
156. Delivery of plasmid DNA to the nucleus using non-viral gene transfection in tumor cell lines and primary tumors
Jill A. Gershan, James J. Weber and Rimas J. Orentas
Mol Ther 9: S59-S60; doi:10.1016/j.ymthe.2004.06.080
157. Clinical evaluation of pain and muscle damage induced by electroporation of skeletal muscle in humans
Rune Kjeken, Torunn Elisabeth Tjelle, Dag Kvale and Iacob Mathiesen
Mol Ther 9: S60-S60; doi:10.1016/j.ymthe.2004.06.079
158. Transient Immunosuppresion by CTLA4Ig and Anti-CD40L Promotes Long-Term Tolerance Specifically Against HFVIII in Hemophilia A Mice Following Naked DNA Transfer
Peiqing Ye, Ling Zhou, Zhenping Shen, Arthur R. Thompson, David J. Rawlings, Hans D. Ochs and Carol H. Miao
Mol Ther 9: S60-S60; doi:10.1016/j.ymthe.2004.06.094
159. Vector genome loss does not account for decline of plasma cFVIII protein in hemophilic dogs that demonstrate long term clinical correction following helper-dependent adenoviral gene therapy
W. Michael McCormack Jr., Terry K. Bertin, Kiran Ubhayakar, Margaretha Guenther, Viraj P. Mane, Philip Ng, Timothy C. Nichols, Milton J. Finegold, Donna Palmer, Arthur Beaudet and Brendan H. Lee
Mol Ther 9: S61-S61; doi:10.1016/j.ymthe.2004.06.119
160. Overcoming the size limitations of gene transfer vectors: using segmental trans-splicing to deliver the coding sequence of Von Willebrand factor
Robert G. Pergolizzi, Rachel Dragos, Katsutoshi Nakayama, Denisa Wagner and Ronald G. Crystal
Mol Ther 9: S61-S61; doi:10.1016/j.ymthe.2004.06.120
161. Novel pseudotyped AAV vectors for hemophilia B gene therapy
Lili Wang, Jean-Pierre Louboutin, Timothy C. Nichols and James M. Wilson
Mol Ther 9: S61-S62; doi:10.1016/j.ymthe.2004.06.121
162. Neonatal gene therapy induces tolerance in dogs but not cats
Lingfei Xu, Patty O'Donnell, Tom O'Malley, Mark E. Haskins, Wan-Ching Chan, Yuli Liu and Katherine P. Ponder
Mol Ther 9: S62-S62; doi:10.1016/j.ymthe.2004.06.122
163. Phenotypic correction of a hemophilia B dog following systemic administration of a helper-dependent ad vector encoding canine coagulation factor IX
Nicola Brunetti-Pierri, Donna Palmer, Timothy C. Nichols, Arthur L. Beaudet and Philip Ng
Mol Ther 9: S62-S63; doi:10.1016/j.ymthe.2004.06.123
164. Secretion of human recombinant factor IX from cells of adipose, myogenic and hepatic origin transduced with replication-defective HSV-1 genomic vectors
Julie Fradette, Ryan Flanigan, David M. Krisky, William F. Goins and Joseph C. Glorioso
Mol Ther 9: S63-S63; doi:10.1016/j.ymthe.2004.06.124
165. Long-term factor VIII expression and phenotypic correction in a murine model of hemophilia A achieved by immunosuppression and non-viral gene transfer using the sleeping beauty transposon
John R. Ohlfest, Scott Perkinson, Paul Lobitz, Joel Frandsen, R. Scott McIvor, Perry Hackett, Karl Clark, Jeff Essner, Nigel Key and David A. Largaespada
Mol Ther 9: S63-S63; doi:10.1016/j.ymthe.2004.06.125
166. Induction of immune tolerance and phenotypic rescue of hemophilic mice by stem cell mediated gene transfer
Brian W. Bigger, Elena K. Siapati, Ajay Mistry, Simon N. Waddington, Megha S. Nivsarkar, Maxine V. Holder, Chris Ridler, Geoff Kemball-Cook, Robyn R. Ali, Stuart Forbes, Charles Coutelle, Nick Wright, Malcolm Alison, Adrian Thrasher, Dominique Bonnet and Michael Themis
Mol Ther 9: S64-S64; doi:10.1016/j.ymthe.2004.06.126
167. Partial correction of the hemophilic phenotype in mice implanted with encapsulated human primary myoblasts secreting FIX
Jianping Wen, Frederick A. Ofosu and Gonzalo Hortelano
Mol Ther 9: S64-S64; doi:10.1016/j.ymthe.2004.06.127
168. EIAV-based vectors for the treatment of haemophilia A
Pippa A. Radcliffe, Fraser J. Wilkes, Georgina L. Beard, Susan M. Kingsman and Kyriacos A. Mitrophanous
Mol Ther 9: S64-S64; doi:10.1016/j.ymthe.2004.06.128
169. Intrapancreatic injections of adeno-associated virus vectors for local gene expression
Scott A. Loiler, Qiushi Tang, Marcel Perret-Gentil, Martha L. Campbell-Thompson, Mark A. Atkinson and Terence R. Flotte
Mol Ther 9: S64-S65; doi:10.1016/j.ymthe.2004.06.129
170. Ex vivo gene therapy of metabolic liver disorders using uncultured and lentivirally transduced hepatocytes
Tuan Huy Nguyen, Jacques Birraux, Barbara Wildhaber, Catherine Fux-Cametti, Claude Le Coultre and Didier Trono
Mol Ther 9: S65-S65; doi:10.1016/j.ymthe.2004.06.130
171. Enhancing hepatocyte gene transfer with baculovirus GP64 Glycoprotein
Yubin Kang, Litao Xie, Diane Thi Tran, Melissa Hickey, Colleen S. Stein, Beverly L. Davidson and Paul B. McCray Jr
Mol Ther 9: S65-S65; doi:10.1016/j.ymthe.2004.06.131
172. Comparison of adenoviral and adeno-associated viral vectors for pancreatic gene delivery in vivo
Alfred Y. Wang, Peter D. Peng, Anja Ehrhardt, Theresa A. Storm and Mark A. Kay
Mol Ther 9: S66-S66; doi:10.1016/j.ymthe.2004.06.132
173. Adenovirus-mediated gene transfer to mouse and dog pancreas in vivo
Eduard Ayuso, Miguel Chillon, Felix Garcia, Judith Agudo, Anna Andaluz, Virginia Haurigot, Assumpcio Bosch, Pedro J. Otaegui and Fatima Bosch
Mol Ther 9: S66-S66; doi:10.1016/j.ymthe.2004.06.133
174. High efficiency HDAd-mediated hepatic transduction can be achieved by delivery into the surgically isolated liver of nonhuman primates
Nicola Brunetti-Pierri, William Cioffi, David Iannitti, Thomas Ng, Donna Palmer, Arthur Beaudet, Milton Finegold, Karen Rice, Dee Carey and Philip Ng
Mol Ther 9: S66-S66; doi:10.1016/j.ymthe.2004.06.134
175. A clinical trial in Japan of retroviral-mediated gene transfer to bone marrow CD34+ cells as a treatment of adenosine deaminase (ADA)-deficiency
Makoto Otsu, Tadashi Ariga, Yoshihiro Maeyama, Jukei Yoshida, Satoru Nakajima, Miyuki Kida, Nariaki Toita, Norikazu Hatano, Nobuaki Kawamura, Motohiko Okano, Ryouji Kobayashi, Osamu Tatsuzawa, Masafumi Onodera, Fabio Candotti, Kunihiko Kobayashi and Yukio Sakiyama
Mol Ther 9: S67-S67; doi:10.1016/j.ymthe.2004.06.135
176. In vivo selective enhancement of correction of human X-linked chronic granulomatous disease neutrophils in NOD/SCID mice transplanted with CD34+ stem cells transduced with a bicistronic gp91phox/benzyl guanine resistant methylguanine methyltransferase vector
Uimook Choi, Kouhei Yamashita, Lanise Caldwell and Harry L. Malech
Mol Ther 9: S67-S67; doi:10.1016/j.ymthe.2004.06.136
177. Lentiviral Vector Mediated ADA Gene Transfer in ADA-Deficient SCID Mice
Denise A. Carbonaro, Xiangyang Jin, Dinithi Senadherra, Karen Pepper, Denise Petersen, Xiao-Jin Yu, Dianne Skelton and Donald B. Kohn
Mol Ther 9: S68-S68; doi:10.1016/j.ymthe.2004.06.137
178. Site-Specific Base Alteration in the Promoter Region of the Human Gamma Globin Gene by Single-Stranded Oligonucleotides for Gene Therapy of Sickle Cell Disease
W. Yin, B. T. Kren and C. J. Steer
Mol Ther 9: S68-S68; doi:10.1016/j.ymthe.2004.06.138
179. Oncoretroviral Vector-Mediated Gene Therapy for Murine WAS Fails to Correct Most of the Deficient Biological Responses to S. pneumonia or M. bovis
Ted S. Strom, Jon McCullers, Robert Rutschman, Peter Murray, Marguerite Evans-Galea, John M. Cunningham and Arthur W. Nienhuis
Mol Ther 9: S68-S69; doi:10.1016/j.ymthe.2004.06.139
180. Use of Skeletal Muscle for Regulated Expression of Parathyroid Hormone to Treat Hypoparathyroidism
Maja Z. Salva, Jeffrey Bonadio and Stephen D. Hauschka
Mol Ther 9: S69-S69; doi:10.1016/j.ymthe.2004.06.140
181. Human CBS (Cystathionine |[beta]|-Synthase) Gene Transfer Mediated by Recombinant Adeno-Associated Virus Vector
Hyun-Jeong Oh, Eun-Sook Park, Warren Kruger, Sung-Chul Jung and Jin-Sung Lee
Mol Ther 9: S69-S70; doi:10.1016/j.ymthe.2004.06.141
182. Towards the Correction of the Genetic Defect in Corneal Keratinocytes from Patients with Macular Corneal Dystrophy Type II
Stefano Ferrari, Giuliana Ferrari, Claudia Rossi, Annarita Miccio, Nicola Volpi, Fulvio Mavilio, Graziella Pellegrini and Michele De Luca
Mol Ther 9: S70-S70; doi:10.1016/j.ymthe.2004.06.142
183. Hemochromatosis: AAV Coding an Antisense Gene Against DMT-1 Iron Transporter in Intestinal Epithelial Cells Acts as RNAi. And Inhibits Iron Transport
Fernando E. Ezquer, Marco T. Nunez and Yedy Israel
Mol Ther 9: S70-S70; doi:10.1016/j.ymthe.2004.06.143
184. Evaluation of Cystine Transport in Cultured Human Kidney Cells: Primer to Gene Therapy of Cystinuria
Sreedhar Sagi, Thomas Knoll, Axel Schaaf, Peter Alken and Maurice Stephan Michel
Mol Ther 9: S70-S71; doi:10.1016/j.ymthe.2004.06.144
185. Systemic Protein Delivery by Muscle-Directed Gene Transfer Is Limited by a Local Immune Response
Lixin Wang, Eric Dobrzynski, Ou Cao and Roland Herzog
Mol Ther 9: S71-S71; doi:10.1016/j.ymthe.2004.06.147
186. Phenotypic Correction of Hemophilic Mice Using Hematopoietic Stem Cells Transduced with an MSCV-Based Oncoretroviral Vector
Morvarid Moayeri, Ali Ramezani, Richard A. Morgan, Teresa S. Hawley and Robert G. Hawley
Mol Ther 9: S71-S72; doi:10.1016/j.ymthe.2004.06.145
187. Adeno-Associated Virus Vector-Mediated Soluble Flt-1 Gene Transfer Prevents Diabetic Retinopathy in Spontaneously Diabetic Rat Model
Junichi Ideno, Hiroaki Mizukami, Akihiro Kakehashi, Yuka Saito, Takashi Okada, Akihiro Kume, Masatoshi Kuroki, Masanobu Kawakami, Shun Ishibashi and Keiya Ozawa
Mol Ther 9: S72-S72; doi:10.1016/j.ymthe.2004.06.095
188. Effects of Long-Term Expression of VEGF-A and Sema3A after Gene Delivery In Vivo Using AAV Vectors
Serena Zacchigna, Pattarini Lucia, Arsic Nikola, Zentilin Lorena, Tomasi Sara, Dapas Marina and Giacca Mauro
Mol Ther 9: S72-S73; doi:10.1016/j.ymthe.2004.06.096
189. Sendai Virus Mediated Angiopoietin-1 Gene Therapy for Cardiovascular Diseases
Yoshinori Ito, Jinghua Huang, Takeshi Uzuka, Yukiko Honma, Hironari Dehari, Masayoshi Kobune, Kiminori Nakamura, Makoto Inoue, Mamoru Hasegawa and Hirofumi Hamada
Mol Ther 9: S73-S73; doi:10.1016/j.ymthe.2004.06.097
190. Myocardial Gene Therapy by Naked Angiopoietin-1 Plasmid Injection Efficiently Induces Angiogenesis and Prevents the Remodeling Following Acute Myocardial Infarction
Takeshi Uzuka, Yoshinori Ito, Masayuki Morikawa, Jinghua Huang, Masayoshi Kobune, Kiminori Nakamura, Yukiko Honma, Keiji Ishii, Tomio Abe and Hirofumi Hamada
Mol Ther 9: S73-S73; doi:10.1016/j.ymthe.2004.06.098
191. Improvement of Myocardial Dysfunction by Therapeutic Angiogenesis Induced by Transfection of HGF Gene Using Left Ventricular Electromechanical Mapping in Porcine Chronic Myocardial Infarction Model
Junya Azuma, Yosiaki Taniyama, Motokuni Aoki, Yasuhumi Kaneda, Toshio Ogihara and Ryuichi Morisita
Mol Ther 9: S74-S74; doi:10.1016/j.ymthe.2004.06.099
192. Cardiac-Specific and Hypoxia-Responsive Vascular Endothelial Growth Factor Expression in Ischemic Hearts
Hua Su, Yu Huang, Alicia Barcena, Janice Arakawa-Hoyt, Shuji Joho, Richard Sievers, William Grossman and Yuet Wai Kan
Mol Ther 9: S74-S74; doi:10.1016/j.ymthe.2004.06.100
193. Hypoxia-Inducible VEGF Gene Therapy Using the RTP801 Promoter
Donghoon Choi, Minhyung Lee, David A. Bull, Russel Reiss, Chien-Wen Chang, Lane Christensen and Sung Wan Kim
Mol Ther 9: S74-S75; doi:10.1016/j.ymthe.2004.06.101
194. Deltavasc|[trade]| - Phase I Study of Intramuscular Administration of Plasmid Del-1 (Developmentally Regulated Endothelial Cell Locus |[ndash]|1) in Humans with Peripheral Arterial Disease (PAD)
Sanjay Rajagopalan, Jeffrey Snell, Stuart W. Young and Gary L. Schaer
Mol Ther 9: S75-S75; doi:10.1016/j.ymthe.2004.06.102
195. Therapeutic Angiogenesis in Mouse Ischemic Heart after Intramyocardial Injection of a Novel Two Gene Plasmid Vector Co-Expressing High Levels of Human VEGF and bFGF Genes
Phoebe Luo, Kengo Kusano, Tom Tsang, David Harris and Douglas Losordo
Mol Ther 9: S75-S75; doi:10.1016/j.ymthe.2004.06.103
196. Regional Angiogenesis Mediated by Platelet-Derived VEGF in Response to Thrombopoietin Gene Transfer
Hideki Amano, Neil R. Hackett, Koji Shido, Rafael Tejada, Scott Avegilla, Shahin Rafii and Ronald G. Crystal
Mol Ther 9: S75-S76; doi:10.1016/j.ymthe.2004.06.104
197. Do Bone Marrow-Derived Progenitor Cells Contribute to VEGF-Induced Post-Natal Neovascularization?
Lorena Zentilin, Sabrina Tafuro, Nikola Arsic, Serena Zacchigna, Milena Sinigaglia, Sara Tomasi, Lucia Pattarini, Marina Dapas and Mauro Giacca
Mol Ther 9: S76-S76; doi:10.1016/j.ymthe.2004.06.105
198. Cell-Based Gene Therapy for Primary Pulmonary Hypertension Using a Non-Viral Gene Delivery System
Linda N. Liu, Linhong Li, Yidan Zhao, Qiuwang Zhang, Rama Shivakumar, Cornell Allen, Joseph C. Fratantoni, Duncan J. Stewart and David W. Courtman
Mol Ther 9: S76-S77; doi:10.1016/j.ymthe.2004.06.106
199. Circulating Endothelial Progenitor Cells Restore Endothelial Function of Balloon Injured Rabbit Carotid Artery
Tongrong He, Leslie A. Smith, Noel M. Caplice and Zvonimir S. Katusic
Mol Ther 9: S77-S77; doi:10.1016/j.ymthe.2004.06.107
200. Cholesterol Modified Polyurethane as a Matrix for Cell Based Cardiovascular Therapy Using Blood Outgrowth Endothelial Cells (BOEC): Potential for Lentivirus Mediated Gene Therapy
Stanley J. Stachelek, Ivan S. Alferiev, Phillip W. Zoltick, Jeanne M. Connolly, Richard W. Bianco, Robert P. Hebbel and Robert J. Levy
Mol Ther 9: S77-S77; doi:10.1016/j.ymthe.2004.06.108
201. Angiogenic Gene Therapy of Coronary Artery Disease - from Bench to the Clinic
Maciej Malecki, Piotr Kolsut, Zbigniew Religa and Przemyslaw Janik
Mol Ther 9: S77-S78; doi:10.1016/j.ymthe.2004.06.111
202. Using RNA to Inhibit Intimal Hperplasia by Blocking E2F Function
Alice K. Tanner, Joseph Nevins and Bruce Sullenger
Mol Ther 9: S78-S78; doi:10.1016/j.ymthe.2004.06.112
203. Electroporation-Mediated Gene Delivery to Mouse Femoral Arteries in a Model of Vascular Injury
Jennifer L. Young, Daniel Eefting, Paul H.A. Quax and David A. Dean
Mol Ther 9: S78-S78; doi:10.1016/j.ymthe.2004.06.113
204. Angiographic Luminal Loss in Porcine Coronary Arteries is Reduced by Stent-Based Adenovirus-Mediated Antagonism of TGF-|[beta]|1
Clare E. Appleby, Paul A. Kingston, Michel Verhoeven, Anita Driessen and Anthony M. Heagerty
Mol Ther 9: S79-S79; doi:10.1016/j.ymthe.2004.06.114
205. Histopathlogical and Physiological Impact on Monkey Intracranial Aneurysms Transfecting Transforming Growth Factor-Beta-1 Mediated by Adenovirus
Shigeki Ono, Tomoyuki Ogawa, Tomohito Hishikawa, Tomotsugu Ichikawa and Isao Date
Mol Ther 9: S79-S79; doi:10.1016/j.ymthe.2004.06.116
206. Adenovirus-Mediated GTP Cyclohydrolase I Gene Delivery Augments Tetrahydrobiopterin and Restores Nitric Oxide Synthase Function in Hyperglycaemic Human Aortic Endothelial Cells
Shijie Cai and Keith M. Channon
Mol Ther 9: S79-S80; doi:10.1016/j.ymthe.2004.06.117
207. Micro RNAs as Novel siRNA Shuttles
Ryan Boudreau, Haibin Xia and Beverly L. Davidson
Mol Ther 9: S80-S80; doi:10.1016/j.ymthe.2004.06.148
208. Regenerative Properties of Retinoic Acid Receptor |[beta]|2 in Rat Model of Dorsal Rhizotomy
Liang-Fong Wong, Ping K. Yip, Anna Battaglia, John Grist, Lucy E. Walmsley, Malcolm Maden, Susan M. Kingsman, Alan J. Kingsman, Stephen B. McMahon and Nicholas D. Mazarakis
Mol Ther 9: S80-S80; doi:10.1016/j.ymthe.2004.06.149
209. Gene Silencing of Human Huntingtin Using Lentivirus-Delivered shRNA
Scott Q. Harper, Patrick D. Staber, Christine R. Rowley, Xiaohua He, Ines H. Martins, Qinwen Mao, Henry L. Paulson and Beverly L. Davidson
Mol Ther 9: S80-S81; doi:10.1016/j.ymthe.2004.06.150
210. AAV Vector-Mediated Enzyme Replacement Therapy Is Efficacious in Reversing Storage Pathology and Preventing Purkinje Cell Death in a Mouse Model of Niemann-Pick A Disease
Marco A. Passini, Jie Bu, James C. Dodge, Qi Zhao, Tatyana V. Taksir, Holly A. Collins, Catherine R. O'Riordan and Gregory R. Stewart
Mol Ther 9: S81-S81; doi:10.1016/j.ymthe.2004.06.151
211. Creation of a HSV VP22-Sleeping Beauty Fusion Protein To Facilitate Integration of HSV-1 Amplicon Vectors
Hilary A. Stanley, William J. Bowers, Michael A. Mastrangelo and Howard J. Federoff
Mol Ther 9: S81-S81; doi:10.1016/j.ymthe.2004.06.152
212. AAV-Mediated Gene Transfer Protects Against Mitochondrial Optic Neuropathy in Mice
Xiaoping Qi, Liang Sun, John Guy, William W. Hauswirth and Alfred S. Lewin
Mol Ther 9: S82-S82; doi:10.1016/j.ymthe.2004.06.153
213. Peripherally Delivered Glutamic Acid Decarboxylase (GAD) Gene Therapy for Below-Level Spinal Cord Injury Neuropathic Pain
Darren Wolfe, Liu Jun, Hao Shuanglin, Huang Shuahua, Marina Mata, Joseph Glorioso and David Fink
Mol Ther 9: S82-S82; doi:10.1016/j.ymthe.2004.06.154
214. Additive Effects of HSV Vectors Expressing Proenkephalin, Interleukin-4, and Tumor Necrosis Factor Alpha Soluble Receptor To Treat Bone Cancer Pain
James R. Goss, Christine Fetterolf, William Goins, Darren Wolfe, Shaohua Huang, David Krisky, Joseph C. Glorioso, Marina Mata and David J. Fink
Mol Ther 9: S82-S82; doi:10.1016/j.ymthe.2004.06.155
215. Dimerizer-Regulated AADC Expression with Two AAV Vectors in 6-OHDA Lesioned Rats
Laura M. Sanftner, Victor M. Rivera, Lan Feng, Lori Berk, John R. Forsayeth, Tim Clackson and Janet Cunningham
Mol Ther 9: S83-S83; doi:10.1016/j.ymthe.2004.06.156
216. Gene Therapy of Huntington Disease Using RNA Interference and Sleeping Beauty Transposon
Zongyu J. Chen, Xiaoming Ma, Philip Wong, Mikel Roe, Chang-won Park, Betsy T. Kren, Walter C. Low and Clifford J. Steer
Mol Ther 9: S83-S83; doi:10.1016/j.ymthe.2004.06.157
217. Widespread Distribution of Beta-Glucuronidase in the Mouse Brain Is Achieved after a Single Inoculation with a Neuroattenuated HSV Vector: Distribution Differs with Inoculation Site
Bradford K. Berges, John H. Wolfe and Nigel W. Fraser
Mol Ther 9: S84-S84; doi:10.1016/j.ymthe.2004.06.159
218. Nonhuman Primate Models for Retinal and Choroidal Neovascularization Using AAV2-Mediated Overexpression of Vascular Endothelial Growth Factor
Corinna Lebherz, Albert M. Maguire, Alberto Auricchio, Waixing Tang, Tomas S. Aleman, Zhangyong Wei, Rebecca L. Grant, Artur V. Cideciyan, Samuel G. Jacobson, James M. Wilson and Jean Bennett
Mol Ther 9: S84-S84; doi:10.1016/j.ymthe.2004.06.160
219. Prolonged Bioactive Transgene Expression Driven by the HSV Latency Active Promoter 2 (LAP2) in the Peripheral Nervous System
Munmun Chattopadhyay, Darren P. Wolfe, William C. Goins, Shaohua Huang, Joseph C. Glorioso, Marina Mata and David J. FINK
Mol Ther 9: S85-S85; doi:10.1016/j.ymthe.2004.06.161
220. Prolonged Biologically Active Transgene Expression Driven by HSV Latency Active Promoter 2 (LAP2) in Brain In Vivo
Veljko Puskovic, Darren Wolfe, James R. Goss, Shaohua Hang, Joseph C. Glorioso, Marina Mata and David J. Finnk
Mol Ther 9: S85-S85; doi:10.1016/j.ymthe.2004.06.162
221. Developing HSV-Mediated Gene Therapy Vectors To Adjust the Metabolic Imbalance of A|[beta]| in Alzheimer's Disease
Chang-Sook Hong, James R. Goss, William F. Goins, David J. Fink and Joseph C. Glorioso
Mol Ther 9: S85-S86; doi:10.1016/j.ymthe.2004.06.163
222. HSV Amplicon Expression of Single Chain Antibodies Directed Against |[alpha]|-Synuclein Conformers
Kathleen A. Maguire-Zeiss, Eric Yehling, Rita Giuliano, Mark Sullivan and Howard J. Federoff
Mol Ther 9: S86-S86; doi:10.1016/j.ymthe.2004.06.165
223. Delivery of HSV Based Vectors for Correction of CNS Pathology in Mucopolysaccharodosis Type vii (MPS vii)
Srikanth Yellayi, Bradford Berges, John Wolfe, Charles Vite and Nigel Fraser
Mol Ther 9: S86-S86; doi:10.1016/j.ymthe.2004.06.166
224. Adenoviral Co-Delivery of BDNF and Noggin Induces Striatal Neuronal Replacement and Delays Motor Impairment in a Transgenic Model of Huntington's Disease
Sung-Rae Cho, Eva Chmielnicki and Steven A. Goldman
Mol Ther 9: S86-S87; doi:10.1016/j.ymthe.2004.06.168
225. Phenotypic Correction of ALD Mouse after Hematopoietic Cell Transplantation and Evaluation of Hematopoietic Stem Cell Gene Therapy with a Lentivirus Vector
Sonia Benhamida, Fran|[ccedil]|oise Fouquet, Ann Moser, Patrick Aubourg and Nathalie Cartier
Mol Ther 9: S87-S87; doi:10.1016/j.ymthe.2004.06.169
226. Developing a CNS-Specific Inflammatory Model To Investigate Gene Therapy/Inflammation Interactions in the Context of Neurodegeneration
Michelle C. Janelsins, Michael A. Mastrangelo, Howard J. Federoff and William J. Bowers
Mol Ther 9: S87-S87; doi:10.1016/j.ymthe.2004.06.170
227. Anatomical and Behavioral Effects of AAV2-Mediated Delivery of Neurturin to the Rat Striatum Prior to 6-Hydroxydopamine Induced Nigrostriatal Degeneration
Christopher D. Herzog, Mehdi Gasmi, Justine J. Cunningham, Eugene P. Brandon, Anthony Ramirez, Alistair Wilson, Eva K. Hofer, Jennifer Hwang, Leo Manlapaz, Jeffrey H. Kordower, Jeffrey M. Ostrove and Raymond T. Bartus
Mol Ther 9: S88-S88; doi:10.1016/j.ymthe.2004.06.172
228. A Novel Therapeutic Strategy To Treat Brain Ischemia: Over-Expression of Hepatocyte Growth Factor Gene Reduced Ischemic Injury without Cerebral Edema in Rat Model
Munehisa Shimamura, Naoyuki Sato, Toshio Ogihara, Yasufumi Kaneda and Ryuichi Morishita
Mol Ther 9: S88-S88; doi:10.1016/j.ymthe.2004.06.174
229. AAV4 Mediated Gene Transfer in Mucopolysaccharidosis Type VII Mice
Gumei Liu, John A. Chiorini and Beverly L. Davidson
Mol Ther 9: S89-S89; doi:10.1016/j.ymthe.2004.06.175
230. Neural Progenitor Cell Transduction with AAV Serotypes 1 and 4
Gumei Liu, Robert M. Kotin, John A. Chiorini and Beverly L. Davidson
Mol Ther 9: S89-S89; doi:10.1016/j.ymthe.2004.06.178
231. Supplementation of Peripherin/rds Rescues Mutation-Associated Rod and Cone Photoreceptor Defects in Transgenic Mice
May Nour, Muna I. Naash and Steven J. Fliesler
Mol Ther 9: S89-S89; doi:10.1016/j.ymthe.2004.06.179
232. Transplantation of Human Embryonic Stem Cell Derived Oligodendroglial Progenitors for the Treatment of Spinal Cord Injury
Jane Lebkowski, Gabriel Nistor, Giovanna Bernal, Minodora Totoiu, Catherine Priest, Scott Thies, Jerrod Denham and Hans Keirstead
Mol Ther 9: S89-S90; doi:10.1016/j.ymthe.2004.06.181
233. Gene Control as a Therapeutic Intervention: Zinc-Finger Protein Transcription Factors as Regulators of the Molecular Determinants of Neuropathic Pain
Yann Jouvenot, John R. Forsayeth, Siyuan Tan, Andrew McNamara, Raymond A. Chavez and Philip Gregory
Mol Ther 9: S90-S90; doi:10.1016/j.ymthe.2004.06.183
234. Correction of Pathology in Galactosialidosis Mice Crossed into Transgenic Mice Expressing PPCA in Neural Cells
Huimin Hu, Linda Mann, Erik Bonton, Taylor Walker and Alessanrdra d'Azzo
Mol Ther 9: S90-S90; doi:10.1016/j.ymthe.2004.06.185
235. The Fetal Approach: A Novel Therapy for the Treatment of Musculo-Skeletal Disease
Michael Themis, Lisa G. Gregory, Simon N. Waddington, Maxine V. Holder, Kyriacos A. Mitrophanous, Suzanne M. K. Buckley, Brian W. Bigger, Fiona E. Ellard, Lucy E. Walmsley, Pippa Radcliffe, Nick Mazarakis, Mimoun Azzouz, Lorraine Lawrence, Terrence Cook, Faisal A. Allaf, Susan Kingsman and Charles Coutelle
Mol Ther 9: S91-S91; doi:10.1016/j.ymthe.2004.06.164
236. Delivery of VEGF Using AAV Vectors Stimulates Skeletal Muscle Regeneration In Vivo
Nikola Arsic, Serena Zacchigna, Lorena Zentilin, Genaro Ramirez-Correa, Alessandro Salvi, Gianfranco Sinagra and Mauro Giacca
Mol Ther 9: S91-S91; doi:10.1016/j.ymthe.2004.06.167
237. Transgenic Expression of Dp116 in Muscle Does Not Ameliorate Dystrophy in mdx 4cv Mice
Luke M. Judge and Jeffrey S. Chamberlain
Mol Ther 9: S91-S91; doi:10.1016/j.ymthe.2004.06.171
238. A Comparison of Gene Delivery and Vector Systems to Achieve High Levels of Sustained Skeletal Muscle Gene Expression
Hu Sheng Qian, Perry Liu, Paul Szymanski, Peter Kretschmer, Alan Brooks, Maxine Bauzon, Fang Jin, Richard N. Harkins, Richard J. Samulski, Gabor M. Rubanyi and Terry W. Hermiston
Mol Ther 9: S91-S92; doi:10.1016/j.ymthe.2004.06.173
239. Human Myoblast Deimmortalization Using Tat-Mediated Cre Recombinase Delivery
Nicolas J. Caron, Marie-Eve Ducharme, Philippe Mills, Simon P. Quenneville and Jacques P. Tremblay
Mol Ther 9: S92-S92; doi:10.1016/j.ymthe.2004.06.211
240. Immunogenicity of Dystrophins Delivered to Mice by Gutted Adenoviral Vectors
Jie Mi, Leonard Leuse, Jeannine Scott, Shannon Barker, Shanna Sawatzki, Dennis Hartigan-O'Connor and Jeffrey S. Chamberlain
Mol Ther 9: S92-S92; doi:10.1016/j.ymthe.2004.06.176
241. Lentivirus Mediated Dystrophin Expression in mdx Muscles
En Kimura, Sheng Li, Brent Fall, Sanna Sawatzki, Leonard Meuse and Jeffery S. Chamberlain
Mol Ther 9: S92-S93; doi:10.1016/j.ymthe.2004.06.177
242. A Novel MiniDys-eGFP Fusion Gene for Developing Cell-Based Therapies of Duchenne Muscular Dystrophy
Sheng Li, En Kimura, Leonard Meuse, Xin Ye, Brent Fall, Steven D. Hauschka, John Faulkner and Jeffrey S. Chamberlain
Mol Ther 9: S93-S93; doi:10.1016/j.ymthe.2004.06.180
243. Delivery of Igf-I and Dystrophin to Dystrophic mdx muscle
Simone Abmayr, Paul Gregorevic, James M. Allen, Shanna M. Sawatzki and Jeffrey S. Chamberlain
Mol Ther 9: S93-S93; doi:10.1016/j.ymthe.2004.06.182
244. Successful AAV Vector-Mediated Gene Transfer into Canine Skeletal Muscle Required Suppression of Excess Immune Responses
Katsutoshi Yuasa, Madoka Yoshimura, Nobuyuki Urasawa, Katsujiro Sato, Yuko Miyagoe-Suzuki, John McC Howell and Shin'ichi Takeda
Mol Ther 9: S94-S94; doi:10.1016/j.ymthe.2004.06.184
245. Muscle-Derived Stem Cells Display an Extended, but Not Unlimited, Expansion Capability: Implication for Muscle Regeneration
Bridget M. Deasy, Burhan M. Gharaibeh, Michele Jones, Michael A. Lucas and Johnny Huard
Mol Ther 9: S94-S94; doi:10.1016/j.ymthe.2004.06.186
246. Gender Differences in Transplantation Efficiency Using Muscle-Derived Stem Cells for Muscular Dystrophy
Bridget M. Deasy, Aiping Lu, Burhan M. Gharaibeh, Michele Jones, Jessica Tebbets and Johhny Huard
Mol Ther 9: S94-S95; doi:10.1016/j.ymthe.2004.06.187
247. Expressing Full-Length Dystrophin in 50% Cardiomyocytes Corrects Cardiomyopathy in the Mdx Mouse Model for Duchenne Muscular Dystrophy
Yongping Yue, Jeffrey W. Skimming, Mingju Liu, Yujiang Fang, Tammy Strawn and Dongsheng Duan
Mol Ther 9: S95-S95; doi:10.1016/j.ymthe.2004.06.188
248. cFLIP or IKBSR Inhibition of NF-|[kappa]|B Activation in Mouse Myoblast Cells: Potential Application of Gene Therapy for Cancer Cachexia
Zhilong Jiang and Paula R. Clemens
Mol Ther 9: S95-S95; doi:10.1016/j.ymthe.2004.06.189
249. New Canine Models of Duchenne Muscular Dystrophy: Identification and Molecular Characterization
Bruce F. Smith, Lucia Alvarez and Kerriann Sparks
Mol Ther 9: S96-S96; doi:10.1016/j.ymthe.2004.06.190
250. Cross-Correction in Pompe Mice after Immunomodulation and Hepatic Delivery of Recombinant AAA5 and AAV8 Vectors
Kerry O. Cresawn, Clive Wasserfall, Mark A. Atkinson, Cathryn Mah, Thomas J. Fraites Jr., Irene Zolotukhin and Barry J. Byrne
Mol Ther 9: S96-S96; doi:10.1016/j.ymthe.2004.06.191
251. rAAV-Mediated Gene Therapy To Treat Limb Girdle Muscular Dystrophy Type 2D (LGMD-2D)
Christina A. Pacak, Denise Cloutier, Irene Zolotukhin, Gabriel S. Gaidosh, Kevin Campbell, Glenn A. Walter and Barry J. Byrne
Mol Ther 9: S96-S97; doi:10.1016/j.ymthe.2004.06.192
252. Phase II Study of MVA Expressing E6 and E7 of HPV16 in Patients with CIN2/3
Patrick Squiban, Patrice Mathevet, Bernard Huynh, Jean-Pai; Bory and Jean-Marc Balloul
Mol Ther 9: S97-S97; doi:10.1016/j.ymthe.2004.06.193
253. Regression of Large Solid Tumors Using Engineered Drug Resistant Immunocompetent Cells and Selective Chemotherapy
Douglas W. McMillin, Becker Hewes, Bagirath Gangadharan and H. Trent Spencer
Mol Ther 9: S97-S98; doi:10.1016/j.ymthe.2004.06.194
254. Vaccination of Recurrent Glioma Patients with Tumour Lysate-Pulsed Dendritic Cells Elicits Immune Responses: Results of a Clinical Phase I/II Trial
Ryuya Yamanaka, Junpei Homma, Naoki Yajima, Naoto Tsuchiya and Ryuichi Tanaka
Mol Ther 9: S98-S98; doi:10.1016/j.ymthe.2004.06.195
255. Potent Cancer Immunotherapy with Dendritic Cells Generated from Genetically Modified Hematopoietic Stem Cells
Tsukasa Nabekura, Hiromitsu Nakauchi, Toshirou Nagasawa and Masafumi Onodera
Mol Ther 9: S98-S98; doi:10.1016/j.ymthe.2004.06.196
256. Importance of Temporal Control of HSVtk Gene Therapy in Combination with T Cell Based Therapies for Cancer
Luis A. Sanchez-Perez, Michael Gough, Jill Thompson and Richard G. Vile
Mol Ther 9: S98-S98; doi:10.1016/j.ymthe.2004.06.197
257. AAV Vector-Loading DC with an Autoimmune Domain-Depleted HCV Core Gene Stimulates High Anti-Core and Low Anti-Self CTL
Maurizio Chiriva-Internati, Yong Liu, Rongcheng Luo, Changxuan You and Paul L. Hermonar
Mol Ther 9: S98-S99; doi:10.1016/j.ymthe.2004.06.198
258. Multi-Modality Non-Invasive Imaging of NK-92 Cells Trafficking and Tumor Targeting in Mice
Vilia Tourkova, Michael Doubrovin, Malgorzata Dabrowska, Jelena Vider, Shangive Cai, Ronald Finn, Juri Gelovani Tjuvajev and Vladimir Ponomarev
Mol Ther 9: S99-S99; doi:10.1016/j.ymthe.2004.06.199
259. In Vivo Suicide Gene Therapy of Human T Lymphocytes in a Murine Xenograft Model
Bruno Nervi, Michael Rettig, Julie Ritchey, John Walker, Gerhard Bauer, Philip Herrbrich, Jan A. Nolta and John F. DiPersio
Mol Ther 9: S99-S100; doi:10.1016/j.ymthe.2004.06.200
260. Anti-Tumor Response by Adenovirus-Mediated, Tumor Specific Expression of a Pro-Apoptotic Protein (TRAIL) and a Heat Shock Protein (GRP94)
Nelson C. Di Paolo, Shaoheng Ni and Andre Lieber
Mol Ther 9: S100-S100; doi:10.1016/j.ymthe.2004.06.210
261. Immune Evasion in Gene Therapy
Rob C. Hoeben, Martine Ossevoort, Birgit M. Visser, Arnaud Zaldumbide, Ellen I. Van der Voort, Diana J. Van den Wollenberg and Rene E. Toes
Mol Ther 9: S100-S100; doi:10.1016/j.ymthe.2004.06.201
262. Dendritic Cell (DC) Vaccine Loaded with Apoptotic Tumor Fragments Effectively Suppress Preestablished Malignant Melanoma in Mice
Hidetsugu Asada, Tsunao Kishida, Hideyo Hirai, Jiro Imanishi and Osam Mazda
Mol Ther 9: S100-S101; doi:10.1016/j.ymthe.2004.06.202
263. Antigen Epitope-Expressing Cytokines for DNA Immunization
Xianghui He, Tom C. Tsang, Tong Zhang, Phoebe Luo and David T. Harris
Mol Ther 9: S101-S101; doi:10.1016/j.ymthe.2004.06.203
264. Non-Invasive Monitoring of the Response of Orthotopic Bladder Tumors to GM-CSF Gene Therapy Using the Prostate Specific Antigen Gene as a Reporter
Qinghui Wu, Ratha Mahendran and Kesavan Esuvaranathan
Mol Ther 9: S101-S101; doi:10.1016/j.ymthe.2004.06.204
265. ImmunoVexEx Vivo: A Herpes Simplex Virus-Based, Dendritic Cell-Mediated Anti-Cancer Vaccine Platform
Philip Reay, Mei Yi-Sun, Binlei Liu, Yvonne McGrath, Madeleine Wakeling, Justin John, Emma Turnbull, Suzanne Thomas and Rob Coffin
Mol Ther 9: S102-S102; doi:10.1016/j.ymthe.2004.06.205
266. OncoVEX: A Family of Oncolytic Herpes Simplex Viruses Optimised for Therapeutic Use
Binlei Liu, Ziquin Han, Guy Simpson and Rob Coffin
Mol Ther 9: S102-S102; doi:10.1016/j.ymthe.2004.06.206
267. Enhancement of T-Cell Immunity by CEA Delivery to Dendritic Cells with Adenovirus Retargeted Via sCAR-Fibritin-CD40L
Papia T. Banerjee, Stephan G. Klinz, Alexander V. Pereboev, Douglas R. Nelson, James S. Huston, David T. Curiel and Stephen D. Gillies
Mol Ther 9: S102-S103; doi:10.1016/j.ymthe.2004.06.207
268. Enhancement of DNA Vaccine Potency by Coadministration of a Tumor Antigen Gene and DNA Encoding Serine Protease Inhibitor-6
Chien-fu Hung, Taewoo Kim and T. C. Wu
Mol Ther 9: S103-S103; doi:10.1016/j.ymthe.2004.06.208
269. Targeting Self Antigens through Allogeneic TCR Gene Transfer
Moniek de Witte, Miriam Coccoris, Monika C. Wolkers, Marly van den Boom, Helmut W. Kessels and Ton N. Schumacher
Mol Ther 9: S103-S103; doi:10.1016/j.ymthe.2004.06.209
270. Treatment of CT26 Tumors with Dendritic Cells Transduced with a Recombinant SV40 Vector Expressing Interleukine 15
Maria Vera, Gloria G. Aseguinolaza, Nerea Razquin, Ignacio Melero, Jesus Prieto and Puri Fortes
Mol Ther 9: S103-S103; doi:10.1016/j.ymthe.2004.06.225
271. Helper-Dependent, Capsid-Modified Adenoviral Vectors for Immunotherapy of Breast Cancer
Nelson C. Di Paolo, Daniel Stone, Dmitry Shayakhmetov and Andre Lieber
Mol Ther 9: S104-S104; doi:10.1016/j.ymthe.2004.06.226
272. Development of |[ldquo]|Full|[rdquo]|-Closed Sterile and Automatic Retroviral Gene Transfer System for Clinical Gene Therapy
Shin Kaneko, Makoto Otsu, Yuichi Hasegawa, Hiroshi Kojima, Takashi Shimizu, Takashi Fukushima, Ryo Sumazaki, Masafumi Onodera and Toshiro Nagasawa
Mol Ther 9: S104-S104; doi:10.1016/j.ymthe.2004.06.228
273. Long-Term Effects of Plasmid-Mediated Growth Hormone Releasing Hormone in Dogs
Catherine M. Tone, Dawn M. Cardoza, Robert H. Carpenter and Ruxandra Draghia-Akli
Mol Ther 9: S105-S105; doi:10.1016/j.ymthe.2004.06.230
274. Combination of a Second Generation Genetically Modified Herpes Simplex Virus 1 (HSV 1) with Paclitaxel in the Treatment of Breast Cancer In Vitro
Jennifer Hu, G. Hallden, Claire Shorrock, Guy Simpson, Rob Coffin, T. Kamalati and R. Coombes
Mol Ther 9: S105-S105; doi:10.1016/j.ymthe.2004.06.231
275. Prostate Targeting Peptides Via the Prostate Specific Membrane Antigen
Shawn E. Lupold and Ronald Rodriguez
Mol Ther 9: S105-S106; doi:10.1016/j.ymthe.2004.06.212
276. Evaluation of an Oncolytic Adenovirus: Efficacy Studies on Primary Human Tumor Cell Cultures and Safety Studies in Non-Human Primates
Shaoheng Ni, Anuj Gaggar, Pavel Sova, Robert Strauss, Nelson C. DiPaolo and Andre Lieber
Mol Ther 9: S106-S106; doi:10.1016/j.ymthe.2004.06.213
277. Variability in Infectivity of Primary Cell Cultures of Human Brain Tumors with HSV-1 Amplicon Vectors
Maria A. Rueger, Alexandra Winkeler, Hrvoje Miletic, Christine Kaestle, Raphaela Richter, Gabriele Schneider, Juergen A. Hampl, Cornel Fraefel and Andreas H. Jacobs
Mol Ther 9: S106-S106; doi:10.1016/j.ymthe.2004.06.214
278. Hypoxia Reduces Adenoviral Replication in Cancer Cells by Down-Regulation of Viral Protein Expression
Teona Pipiya, Harald Sauthoff, Yao Qi Huang, Benjamin Chang, William N. Rom and John G. Hay
Mol Ther 9: S106-S107; doi:10.1016/j.ymthe.2004.06.216
279. Methotrexate Chemotherapy of L1210 Leukemia in Mice Transplanted with Transgenic Marrow Expressing Drug-Resistant Dihydrofolate Reductase
Joel L. Frandsen, Debra Swanson and R. Scott McIvor
Mol Ther 9: S107-S107; doi:10.1016/j.ymthe.2004.06.217
280. The Use of the Regulatory Sequences of H19 and IGF2 Genes in DNA Based Therapy of Colorectal Rat Liver Metastases
Patricia Ohana, Pinhas Schacter, Basem Ayesh, Aya Mizrahi, Suhail Ayesh, Tatiana Birman, Tamar Schneider, Imad Maatouk, Peter J. K. Kuppen, Nathan de Groot, Abraham Czerniak and Abraham Hochberg
Mol Ther 9: S107-S108; doi:10.1016/j.ymthe.2004.06.218
281. Modulating the Immune Response to Oncolytic Measles Viruses
Rae M. Myers, Mary E. Harvey, Diane C. Soeffker, Suzanne M. Greiner, Kah-Whye Peng and Stephen J. Russell
Mol Ther 9: S108-S108; doi:10.1016/j.ymthe.2004.06.219
282. Transient Adenoviral Methylpurine DNA Glycosylase Overexpression Imparts Chemotherapeutic Sensitivity to Human Breast Cancer Cells
Mikael Rinne, David Caldwell, Ying He and Mark R. Kelley
Mol Ther 9: S108-S108; doi:10.1016/j.ymthe.2004.06.220
283. Adeno-Associated Viral Vector Expression Angiostatin and IL-15 for Brain Cancer Gene Therapy
Horng Jyh Harn, Kuang Wen Liao and Shinn Zong Lin
Mol Ther 9: S108-S108; doi:10.1016/j.ymthe.2004.06.221
284. Oncolytic Adenovirus E1B-19kD Deletion and E3B Retention Results in Both Enhanced Potency and Tumor Necrosis Factor - Mediated Selectivity
Ta-Chiang Liu, Yaohe Wang, Gunnel Hallden, Jennelle Francis, Gabriel Brooks, Nick Lemoine and David Kirn
Mol Ther 9: S109-S109; doi:10.1016/j.ymthe.2004.06.222
285. Evidence of Antiangiogenic and Antimetastatic Activities of the Recombinant Disintegrin Domain of Metargidin
Veronique Trochon-Joseph, Dominique Renoir, Lluis M. Mir, Annick Thomaidis, Paule Opolon, Elisabeth Connault, Hong Li, Christophe Grenet, Francoise Fauvel-Lafeve, Jeannette Soria, Chantal Legrand, Claudine Soria, Michel Perricaudet and He Lu
Mol Ther 9: S109-S109; doi:10.1016/j.ymthe.2004.06.223
286. Conditionally Replicating Adenoviral Vectors for Glioblastoma Treatment
Bertie H. C. G. M. de Leeuw, Maarten ter Horst, Mark Rodijk, Michael Brenner, Rob C. Hoeben and Peter A. E. Sillevis Smitt
Mol Ther 9: S109-S109; doi:10.1016/j.ymthe.2004.06.224
287. Enhancement of Therapeutic Efficacy of G207 for the Treatment of Malignant Glioma Through Musashi1 Promotor Retargeting of ICP 34.5 Gene-Mediated Virulence
Takahito Yazaki, Ryuichi Kanai, Hideyuki Tomita, Atsuo Shinoda, Hideyuki Okano and Takeshi Kawase
Mol Ther 9: S110-S110; doi:10.1016/j.ymthe.2004.06.830
288. Synergism Between a Conditionally Replicating Adenovirus Expressing p53 and Oxaliplatin in the Antiproliferative Effects on Human Colon Cancer Cell Lines
Dinja Oosterhoff, Victor W. van Beusechem, Epie Boven, Herbert M. Pinedo and Winald R. Gerritsen
Mol Ther 9: S110-S110; doi:10.1016/j.ymthe.2004.06.227
289. Cisplatin and Doxorubicin Enhance the Activity of the CRAd Ad5-|[Delta]|24RGD Against Osteosarcoma Cell Lines but Not Primary Osteosarcoma Cells
Harm C. A. Graat, M. Adhiambo Witlox, Frederik H. E. Schagen, Gertjan J. L. Kaspers, David T. Curiel, Marco N. Helder, Johannes Bras, Gerard R. Schaap, Winald R. Gerritsen, Paul I. J. M. Wuisman and Victor W. van Beusechem
Mol Ther 9: S110-S110; doi:10.1016/j.ymthe.2004.06.229
290. Demonstration of Antitumor Efficacy with an Oncolytic Adenovirus CG8840 for the Treatment of Bladder Cancer in an Orthotopic Tumor Model in Mice
Nagarajan Ramesh, Ying Ge, Jun Liu, Deborah Farson, Melinda Van Roey, Virginia Rojas, Peter Working and DeChao Yu
Mol Ther 9: S111-S111; doi:10.1016/j.ymthe.2004.06.232
291. Enhanced Therapeutic Effect of Adenoviral Vector-Mediated RTVP-1 Gene Therapy in Combination with Irradiation for Prostate Cancer
Tetsuo Fujita, Koji Naruishi, Nobuyuki Kusaka, Takefumi Satoh, Xiaorong Ji, Jianxiang Wang, Xiaohong Zhu, Guang Yang, Alexei A. Goltsov, Terry L. Timme, Maria T. Vlachaki, Bin S. Teh, E. Brian Butler and Timothy C. Thompson
Mol Ther 9: S111-S111; doi:10.1016/j.ymthe.2004.06.233
292. Modification of the p53 Transgene of a Replication-Competent Adenovirus Improves p53 Stability and Cancer Cell Killing
Harald Sauthoff, Teona Pipiya, Shu Chen, Sheila Heitner, Yao Qi Huang, William N. Rom and John G. Hay
Mol Ther 9: S112-S112; doi:10.1016/j.ymthe.2004.06.234
293. The Epithelial Glycoprotein-2 Promoter Controls Selective and Efficient Killing of Epithelium Derived Cancer Cells
Willemijn M. Gommans, Marianne G. Rots, Pamela M. J. McLaughlin, Simone J. van Eert, Martin C. Harmsen, Masato Yamamoto, David T. Curiel and Hidde J. Haisma
Mol Ther 9: S112-S112; doi:10.1016/j.ymthe.2004.06.235
294. Herpes Simplex Virus Mediated Oncolysis is an Effective Intratumoral Therapy in High-Risk Neuroblastoma Tumor Models
Nehal S. Parikh, Mark A. Currier, Lisa C. Adams, Margaret H. Collins and Timothy P. Cripe
Mol Ther 9: S112-S113; doi:10.1016/j.ymthe.2004.06.236
295. Selective Breast Tumor Growth Suppression Mediated by the Enhanced Breast Cancer-Specific Promoter
Chi-Ping Day, Kun-Ming Rau and Mien-Chie Hung
Mol Ther 9: S113-S113; doi:10.1016/j.ymthe.2004.06.237
296. Combination Therapy with Adenovirus (Ad5) and Cytotoxic Drugs Can Act Synergistically To Induce Cell Death in Carcinoma Cell Lines in Culture
Gunnel K. Hallden, Jiang Hui Meng, Richard Hill, Yaohe Wang, Jennelle Francis, Nicholas N. Lemoine and David H. Kirn
Mol Ther 9: S113-S113; doi:10.1016/j.ymthe.2004.06.238
297. Development of HVJ-E High Throughput Gene Function Screening System: Screening of Endothelial Cell Growth Factors
Tomoyuki Nishikawa, Hironobu Nakagami, Chiah Yian Yo and Yasufumi Kaneda
Mol Ther 9: S113-S114; doi:10.1016/j.ymthe.2004.06.239
298. RNA Mediated Transcriptional Gene Silencing in Human Cells
Kevin V. Morris, Chris Chung and David J. Looney
Mol Ther 9: S114-S114; doi:10.1016/j.ymthe.2004.06.240
299. Insertion Site Analysis and In Vivo Selection
Michael A. Harkey, Michael Weinreich, Yasuo Nagasawa, Patrick A. Navas and C. Anthony Blau
Mol Ther 9: S114-S115; doi:10.1016/j.ymthe.2004.06.241
300. Targeted Gene Correction in Mouse Embryonic Stem Cells Using Helper-Dependent Adenoviral Vectors
Fumi Ohbayashi, Michael A. Balamotis and Ko Mitani
Mol Ther 9: S115-S115; doi:10.1016/j.ymthe.2004.06.242
301. CID-Mediated In Vivo Selection: Heterogeneity Among Large Animal Models
Robert E. Richard, R. Angelo De Claro, Sylvia Chien, Hans-Peter Kiem, Tim Clackson, Robert Andrews and C. Anthony Blau
Mol Ther 9: S115-S115; doi:10.1016/j.ymthe.2004.06.243
302. Engineered Zinc Finger Transcription Factors: A Platform for Therapeutic Gene Regulation with Exquisite Specificity
Dmitry Guschin, Steve Zhang, Lei Zhang, Siyuan Tan, Victor Bartsevich, Casey Case, Edward Rebar and Philip Gregory
Mol Ther 9: S116-S116; doi:10.1016/j.ymthe.2004.06.244
303. Impaired Nuclear Transport and Virus Uncoating Limit Recombinant Adeno-Associated Virus 2 Vector-Mediated Transduction of Primary Murine Hematopoietic Cells
Li Zhong, Weiming Li, Zuocheng Yang, Njeri Maina, Keyun Qing, Yanjun Li, Linyuann Chen, Mengqun Tan, Rebecca J. Chan, Weihong Zhao, Steven H. Larsen, Mervin C. Yoder, Weinian Shou and Arun Srivastava
Mol Ther 9: S116-S116; doi:10.1016/j.ymthe.2004.06.245
304. Atelocollagen-Based Cell Transfection Array Allows High-Throughput Screening of Gene Functions
Kimi Honma, Hiroshi Ito, Syunji Nagahara, Teruo Miyata and Takahiro Ochiya
Mol Ther 9: S116-S117; doi:10.1016/j.ymthe.2004.06.246
305. Regulation of Targeted Gene Repair by DNA Replication and by DNA Replication Arrest
Eric B. Kmiec, Jennifer Sonntag and Erin Brachman
Mol Ther 9: S117-S117; doi:10.1016/j.ymthe.2004.06.247
306. Noninvasive Monitoring of Transgene Expression Using Surrogate Marker Peptides
Linh D. Pham, Suzanne Greiner, Takafumi Nakamura, Kah-Whye Peng, Gabriela A. Rosales, Kent R. Bailey, Pai C. Kao and Stephen J. Russell
Mol Ther 9: S117-S117; doi:10.1016/j.ymthe.2004.06.248
307. A Mechanism for AZT Mediated Enhancement of Transgene Expression
Fayaz R. Khazi, Andrew C. Edmondson and Katherine A. High
Mol Ther 9: S117-S118; doi:10.1016/j.ymthe.2004.06.249
308. A New Model to Functionally Measure Fusion Events in the Liver After Bone-Marrow Transplantation Over Time
Konrad L. Streetz, Denison D. Jenkins, Michael T. Longaker, Karl G. Sylvester and Mark A. Kay
Mol Ther 9: S118-S118; doi:10.1016/j.ymthe.2004.06.250
309. Controlling Embryogenesis Using Engineered Zinc Fingers in Drosophila
Andrew C. Jamieson, Thomas J. Cradick, Bo Guan, Hong Xiao and Pamela M. Carroll
Mol Ther 9: S118-S118; doi:10.1016/j.ymthe.2004.06.251
310. Feasibility and Limitations of Target Gene Repair in Mammalian Cells
Eric B. Kmiec, Li Liu and Hetal Parekh-Olmedo
Mol Ther 9: S118-S119; doi:10.1016/j.ymthe.2004.06.252
311. Targeted Gene Delivery to Selected Liver Segments by Isolated Hepatic Perfusion with Clamping of the Portal Vein
Hiroyasu Kinoshita, Sanae Hisayasu, Atsushi Watanabe, Satoru Suzuki and Takashi Shimada
Mol Ther 9: S119-S119; doi:10.1016/j.ymthe.2004.06.253
312. Developing Qualified Activity and Potency Assays for Gene Therapy and DNA Vaccine Products
Rick Hancock and Christopher Duffy
Mol Ther 9: S119-S119; doi:10.1016/j.ymthe.2004.06.254
313. Ligand-Specific Multiplex Gene Switch Expression in a Mouse Model
David W. Potter, Mohan B. Kumar, Martha A. DiPietro and Subba R. Palli
Mol Ther 9: S119-S119; doi:10.1016/j.ymthe.2004.06.255
314. mRNA Production is the Major Factor Limiting Autogene-Based Cytoplasmic Expression
Jonathan D. Finn, Ian MacLachlan and Pieter R. Cullis
Mol Ther 9: S119-S120; doi:10.1016/j.ymthe.2004.06.256
315. Targeted Gene Repair Exhibits a Polar Bias in the Directionality of Correction
Eric B. Kmiec and Miya Drury
Mol Ther 9: S120-S120; doi:10.1016/j.ymthe.2004.06.257
316. Cystic Fibrosis Airway Epithelial Cells Transfection
Rosalie Maurisse, Yann Fichou, Judy Chen, Claude Ferec, Jian-Sheng Sun and Dieter C. Gruenert
Mol Ther 9: S120-S120; doi:10.1016/j.ymthe.2004.06.258
317. DNA Damage and Homologous Recombination Regulate the Frequency and Process of Targeted Gene Repair
Eric B. Kmiec, Luciana Ferrara, Katie Maguire, Hetal Parekh-Olmedo and Tim Schwartz
Mol Ther 9: S120-S121; doi:10.1016/j.ymthe.2004.06.259
318. Cationic Lipids/Ligands Induce DNA Helix Denaturation and Alter Transcriptional Activity
K. T. Prasad, Madhusudhana N. Rao and Vijaya Gopal
Mol Ther 9: S121-S121; doi:10.1016/j.ymthe.2004.06.260
319. Improvement of Transgene Expression Through the Direct Intrahepatic Injection of Adenoviral Vectors
Julien Swen Crettaz, Pedro Berraondo, Gloria Gonzalez-Aseguinolaza, Veijay Shankar and Laura Ochoa
Mol Ther 9: S121-S121; doi:10.1016/j.ymthe.2004.06.261
320. Effect of Sexual Steroid Hormones on Human egr-1 Promoter
Francisco Martinez-F., Hilda Villegas-C., Alejandro Jimenez-O., Roberto Razo and David T. Curiel
Mol Ther 9: S121-S122; doi:10.1016/j.ymthe.2004.06.262
321. siFECT|[trade]|: Optimised Formulation for the Delivery of siRNA at Minimum Doses and Maximum Specificity
Sebastien Spagnou, Michael Jorgensen, Andrew D. Miller and Michael Keller
Mol Ther 9: S122-S122; doi:10.1016/j.ymthe.2004.06.263
322. Characterization of IFN|[gamma]| Gene Expressions in Rat Tissues with Real Time Quantitative RT-PCR
Baohong Tian, Sarah S. Rentz, Gregory S. Gorman, Rogers Tina and John G. Page
Mol Ther 9: S122-S123; doi:10.1016/j.ymthe.2004.06.264
323. Adenovirus Mediated Transfer of LacZ Gene in the Murine Melanoma Cell B16
Hui Li and Jiansheng Li
Mol Ther 9: S123-S123; doi:10.1016/j.ymthe.2004.06.265
324. The Degron Motif: A Protein Destruction Module with Potent Transcriptional Activation Properties for ZFP-Targeted Gene Regulation
Siyuan Tan, Dmitry Guschin, Carolyn Dent, Andreas Reik, Pei-Qi Liu and Philip D. Gregory
Mol Ther 9: S123-S123; doi:10.1016/j.ymthe.2004.06.266
325. Identification of Mechanistically Distinct Repression Domains at Endogenous Genes Using Engineered Zinc Finger Proteins
Siyuan Tan, Lei Zhang, H. Steven Zhang, Xaohong Zhong, Yann Jouvenot, Andrew W. Snowden, Andrew R. McNamara, Casey C. Case, Carl O. Pabo and Philip D. Gregory
Mol Ther 9: S123-S123; doi:10.1016/j.ymthe.2004.06.267
326. Zinc Finger Protein Targeted Epigenetic Gene Regulation: Toward Directed Long-Term Gene Control
Andrew R. McNamara, Andrew W. Snowden and Philip D. Gregory
Mol Ther 9: S123-S124; doi:10.1016/j.ymthe.2004.06.268
327. Retargetable Oncolytic Measles Viruses for Cancer Virotherapy
Takafumi Nakamura, Kah-Whye Peng, Mary Harvey and Stephen J. Russell
Mol Ther 9: S124-S124; doi:10.1016/j.ymthe.2004.06.269
328. Paramyxovirus Fusion Protein Trimers: Partial Membrane-Proximal Ectodomain Cleavage Enhances Function
Veronika von Messling, Dragana Milosevic, Patricia Devaux and Roberto Cattaneo
Mol Ther 9: S124-S124; doi:10.1016/j.ymthe.2004.06.270
329. Long-Term Transgene Expression by Hepatocytes Transduced with Retroviral Vectors Requires Induction of Immune Tolerance to the Transgene
Juliana Pupi, Carole Guillonneau, Virginie Picard, Maria C. Cuturi, Nicolas Ferry and Ignacio Anegon
Mol Ther 9: S124-S125; doi:10.1016/j.ymthe.2004.06.271
330. Genetic Modification of Murine Embryonic Stem Cells by the Gene Silencing Resistance Retroviral Vector GCDsap
Sanae Hamanaka, Joichi Usui, Satoru Takahashi, Hisahiro Yoshida, Michio Nagata, Makoto Otsu, Shin Kaneko, Toshiro Nagasawa, Hiromitsu Nakauchi and Masafumi Onodera
Mol Ther 9: S125-S125; doi:10.1016/j.ymthe.2004.06.272
331. Human T Cells Efficiently Abort RCR-Infection Through a CEM15/APOBEC3G-Mediated Mechanism
Saskia B. Ebeling, Elles Simonetti, Stephanie Laufs, Frank Giordano, Stefan Fruehauf and Anton Hagenbeek
Mol Ther 9: S125-S126; doi:10.1016/j.ymthe.2004.06.273
332. Dual Gene Transfer and Transgenesis by Novel Lentiviral Vectors Carrying Synthetic Bi-Directional Promoters
Mario Amendola, Mary Anna Venneri, Elisa Vigna and Luigi Naldini
Mol Ther 9: S126-S126; doi:10.1016/j.ymthe.2004.06.274
333. Vector Development by Molecular Evolution: A Selection Procedure for Envelope Proteins Pseudotyping Lentiviral Particles
Christoph A. Merten, Joern Stitz, Klaus Cichutek and Christian J. Buchholz
Mol Ther 9: S126-S126; doi:10.1016/j.ymthe.2004.06.275
334. Micro-Environmental Effects on Gene Transfer by Pseudotyped Lentiviral Vectors
James R. Gilbert and Frank Park
Mol Ther 9: S127-S127; doi:10.1016/j.ymthe.2004.06.276
335. Long-Term Genetic Modification of the Ocular Outflow Tract Coupled with Non-Invasive Real-Time Imaging of Gene Expression
Nils A. Loewen, Michael P. Fautsch, Wu-Lin Teo, Cindy K. Bahler, Douglas H. Johnson and Eric M. Poeschla
Mol Ther 9: S127-S127; doi:10.1016/j.ymthe.2004.06.277
336. Foamy Virus |[mdash]| Adenovirus Hybrid Vectors
Axel Rethwilm, Marcus Picard-Maureau, Florian Kreppel, Dirk Lindemann, Thomas Juretzek, Ottmar Herchenroeder, Martin Heinkelein and Stefan Kochanek
Mol Ther 9: S127-S127; doi:10.1016/j.ymthe.2004.06.278
337. Unrestricted Liver Transduction with AAV Serotype 8 Vector in Mice
Hiroyuki Nakai, Theresa Storm, Sally Fuess and Mark A. Kay
Mol Ther 9: S128-S128; doi:10.1016/j.ymthe.2004.06.279
338. Therapeutic Levels for |[alpha]|1-Antitrypsin Following Intrapleural Administration of a Non-Human Primate Serotype rh10 AAV Vector Expressing |[alpha]|1-Antitrypsin
Bishnu P. De, Nabil Wasif, Neil R. Hackett, Guangping Gao, James M. Wilson and Ronald G. Crystal
Mol Ther 9: S128-S128; doi:10.1016/j.ymthe.2004.06.280
339. Sustained, High-Level Expression of Human Acid Alpha-Glucosidase and Correction of Glycogen Storage Disease Type II (GSD II) with an Adeno-Associated Virus 8 (AAV2/8) Vector Containing a Liver-Specific Promoter
Luis M. Franco, Baodong Sun, Andrew Bird, Haoyue Zhang, Andrea Amalfitano, Y.-T. Chen and Dwight D. Koeberl
Mol Ther 9: S129-S129; doi:10.1016/j.ymthe.2004.06.652
340. Assessment of the Transduction Patterns of Alternative AAV Vector Serotypes in the CNS of Rhesus Macaques
Bruce A. Bunnell, Jason DuFour, Gretchen Belenchia, Xavier Alvarez, Kate Baker, Pete Didier, Andrew Lackner and John H. Wolfe
Mol Ther 9: S129-S129; doi:10.1016/j.ymthe.2004.06.282
341. Autoimmune Anemia in Macaques Following Erythropoietin Gene Therapy
Guangping Gao, Corinna Lebherz, Daniel J. Weiner, Rebecca L. Grant, Roberto Calcedo, Adam Bagg, Yi Zhang and James M. Wilson
Mol Ther 9: S130-S130; doi:10.1016/j.ymthe.2004.06.995
342. Self-Complementary Adeno-Associated Virus 2 (AAV)-T Cell Protein Tyrosine Phosphatase Vector as a Helper-Virus to Improve Transduction Efficiency of Conventional AAV Vectors in vitro and in vivo
Li Zhong, Linyuan Chen, Yanjun Li, Keyun Qing, Rebecca J. Chan, Mervin C. Yoder, Koppal S. Rao and Arun Srivastava
Mol Ther 9: S130-S130; doi:10.1016/j.ymthe.2004.06.287
343. Characterization of Delivery Routes of AAV Vectors for Neonatal Gene Transfer
Tsuyoshi Ogura, HIroaki Mizukami, Jun Mimuro, Takashi Okada, Hiromi Hamada, Akihiro Kume, Hiroyuki Yoshikawa, Yoichi Sakata and Keiya Ozawa
Mol Ther 9: S130-S131; doi:10.1016/j.ymthe.2004.06.290
344. Recombinant Adeno-Associated Virus 2 Suicide Vectors for the Treatment of Human Sarcomas and Mesotheliomas
Marlon R. Veldwijk, Simone Berlinghoff, Stephanie Laufs, Frederik Wenz, Stefan Fruehauf and W. Jens Zeller
Mol Ther 9: S131-S131; doi:10.1016/j.ymthe.2004.06.292
345. Sensitive Molecular Detection of Various Stable Episomal Concatemeric and Integrated Forms of rAAV2 after Long-Term Expression In Vivo
Karim Zaoui, Manfred Schmidt, Denise E. Sabatino, Fayaz R. Khazi, Hanno Glimm, Junwei Sun, Katherine A. High and Christof von Kalle
Mol Ther 9: S131-S132; doi:10.1016/j.ymthe.2004.06.295
346. Characterization of Adeno-Associated Virus Sequences in Human Tissues
Chun-Liang Chen, Ryan L. Jensen, Bruce C. Schnepp, K. Reed Clark and Philip R. Johnson
Mol Ther 9: S132-S132; doi:10.1016/j.ymthe.2004.06.299
347. Pharmacological Regulation of Dendritic Cell Activation: Enhancing Cancer Vaccine Efficacy
Brent A. Hanks, Jianghong Jiang and David M. Spencer
Mol Ther 9: S132-S133; doi:10.1016/j.ymthe.2004.06.283
348. IL-21 and IL-15 Gene Therapy Induces Powerful Antitumor Effect Against Head and Neck Squamous Cell Carcinoma
Hiroshi Nakano, Tsunao Kishida, Hidetsugu Asada, Takashi Shinomiya, Jiro Imanishi, Yasuo Hisa and Osamu Mazda
Mol Ther 9: S133-S133; doi:10.1016/j.ymthe.2004.06.289
349. GM-CSF / IL-2 Fusion Transgene is More Potent than GM-CSF and IL-2 in Combination and is Dependent upon CD8 and NK Cells for Antitumor Effect
John Stagg, Nathaniel Bouganim and Jacques Galipeau
Mol Ther 9: S133-S133; doi:10.1016/j.ymthe.2004.06.296
350. Gene Transfer of Modified Idiotype into Dendritic Cells for Immunotherapy of Non-Hodgkin Lymphomas
Sara Muraro, Attilio Bondanza, Matteo Bellone, Philip Greenberg and Chiara Bonini
Mol Ther 9: S134-S134; doi:10.1016/j.ymthe.2004.06.301
351. Enhanced Therapeutic Efficacy of a Cytokine Expressing Oncolytic Herpes Simplex Virus Against Prostate Cancer
Susan Varghese, Samuel D. Rabkin, Wenzheng Wang and Robert L. Martuza
Mol Ther 9: S134-S134; doi:10.1016/j.ymthe.2004.06.303
352. Intentional Killing of Normal Melanocytes by Gene Transfer Generates Curative Anti Melanoma Immunity without Obligate Autoimmunity
Gregory Daniels, Luis Sanchez-Perez, Timothy Kottke, Rosa M. Diaz, Jill Thompson, Mayoi Lai, Michael Gough, Mahzuz Karim, Andrew Bushell, Heung Chong, Alan Melcher, Kevin Harrington and Richard G. Vile
Mol Ther 9: S134-S135; doi:10.1016/j.ymthe.2004.06.306
353. In a Model of Tumor Dormancy, Long-Term Persistent Leukemic Cells Have Increased B7-H1 and B7.1 Expression and Resist CTL-Mediated Lysis
Aurore Saudemont and Bruno Quesnel
Mol Ther 9: S135-S135; doi:10.1016/j.ymthe.2004.06.309
354. CD8 Immunomagnetic Selection and Interleukin-15 (IL-15) Facilitate the Isolation of Human CD8+ Cytotoxic T-Lymphocytes (CTL) Genetically Engineered To Express an Anti-CD20 Chimeric T-Cell Receptor (cTCR)
Eric Y. Chen, Oliver W. Press and Michael C. Jensen
Mol Ther 9: S135-S135; doi:10.1016/j.ymthe.2004.06.313
355. Specific Lysis of Multiple Myeloma Cells by T-Cells Engineered to Express a Chimeric Immune Receptor Targeting WUE-Antigen
Max S. Topp, Horst D. Hummel, Gabriele Kuntz, Christina Neff and Hermann Einsele
Mol Ther 9: S136-S136; doi:10.1016/j.ymthe.2004.06.318
356. IL-12 Transduced Bone Marrow Cells Home to Bone and Generate Anti-Metastatic Activities in a Mouse Prostate Cancer Model
Hongyu Wang, Guang Yang, Terry L. Timme, Tetsuo Fujita, Koji Naruishi, Xiaorong Ji, Malcolm K. Brenner, Dov Kadmon and Timothy C. Thompson
Mol Ther 9: S136-S136; doi:10.1016/j.ymthe.2004.06.324
357. Selective Depletion of Kupffer Cells Leads to Enhanced Transgene Expression in Rat Liver Following Intraductal Infusion of Naked DNA and DNA Nanoparticles
Hui Dai, Xuan Jiang, Weiseng Lim, Xuesong Jiang, Yong Chen, Hai-Quan Mao and Kam W. Leong
Mol Ther 9: S136-S137; doi:10.1016/j.ymthe.2004.06.284
358. Route of Administration of sec-R Targeted Compacted DNA Influences Both the Site of Expression and Host Immune Response to the Vector
Assem G. Ziady, John Kim, Joseph Colla and Pamela B. Davis
Mol Ther 9: S137-S137; doi:10.1016/j.ymthe.2004.06.286
359. Enhanced Gene Delivery by a Novel Tumor-Specific Vector Containing Peptide and Nucleic Acid Based Nuclear Translocation Signals
Stanley Saamoah-Moffatt, Sandra Wiehle and Richard J. Cristiana
Mol Ther 9: S137-S138; doi:10.1016/j.ymthe.2004.06.288
360. Long-Term Gene Transfer and Expression in Xenografted Human Glioblastoma by Non-Viral Gene Transfer with the Sleeping Beauty Transposon
John R. Ohlfest, Scott Perkinson, Paul Lobitz, Diane Hasz and David A. Largaespada
Mol Ther 9: S138-S138; doi:10.1016/j.ymthe.2004.06.291
361. Reduction of Polyethylenimine Buffering Capacity Enhances In-Vitro Gene Delivery Activity
M. Laird Forrest, Nathan Gabrielson and Daniel W. Pack
Mol Ther 9: S138-S138; doi:10.1016/j.ymthe.2004.06.293
362. Novel Synthetic Poly(hydroxylamidoamine)s Facilitate Efficient and Nontoxic Gene Delivery with Mammalian Cells
Theresa M. Reineke, Yemin Liu and Laura Wenning
Mol Ther 9: S139-S139; doi:10.1016/j.ymthe.2004.06.294
363. Uptake and Intracellular Trafficking of Stabilized and Unstabilized Gene Delivery Particles
Swaroop Mishra, Paul Webster and Mark E. Davis
Mol Ther 9: S139-S139; doi:10.1016/j.ymthe.2004.06.297
364. The Proteasome Metabolizes Non-Viral Gene Delivery Systems
Ji-seon Kim and Kevin G. Rice
Mol Ther 9: S139-S139; doi:10.1016/j.ymthe.2004.06.298
365. Cell Membrane Lipid Rafts Mediate Caveolar Endocytosis of HIV-1 Tat Fusion Proteins
Antonio Fittipaldi, Silvia Agostini, Aldo Ferrari, Caterina Arcangeli, Vittorio Pellegrini, Fabio Beltram and Mauro Giacca
Mol Ther 9: S139-S140; doi:10.1016/j.ymthe.2004.06.300
366. Negative Feedback Inhibition of HIV-1: A Novel HIV-1 LTR-hsp70 Fusion Promoter Directs HIV-1 Inducible siRNA Expression
Hoshang J. Unwalla, James D. Kim, Haitang Li and John J. Rossi
Mol Ther 9: S140-S140; doi:10.1016/j.ymthe.2004.06.302
367. Development of Lentiviral Vectors Carrying shRNA, Ribozyme and RNA Decoy for the Inhibition of HIV-1 Infection
Ming-Jie Li, James Kim, Shirley Li, John Zaia, Jiing-Kuan Yee and John J. Rossi
Mol Ther 9: S140-S140; doi:10.1016/j.ymthe.2004.06.304
368. Pseudotyping HIV Vector with the Spike Envelope Protein of SARS-CoV for Studying Viral Tropism, Immunology and Gene Therapy Applications
Gary P. Kobinger, Heinz Feldmann, Gregory P. Schumer and James M. Wilson
Mol Ther 9: S140-S140; doi:10.1016/j.ymthe.2004.06.305
369. Selective Expansion of Human T Lymphocytes Transduced by HIV Vectors Containing IMPDH2 and Anti-HIV siRNA Genes
Priscilla Yam, Ying Yu, Jerry Wu, Michael C. Jensen, John A. Zaia and Jiing-Kuan Yee
Mol Ther 9: S141-S141; doi:10.1016/j.ymthe.2004.06.307
370. Potent In Vivo Inhibition of HIV-1 Infection in Thy/Liv-SCID-Hu Mice after In Vivo Treatment with a Combination of SV40-Derived Vectors Targeting CCR5 Expression
Mahesh Patel, Pierre Cordelier, David S. Strayer and Harris Goldstein
Mol Ther 9: S141-S141; doi:10.1016/j.ymthe.2004.06.310
371. Complete Inhibition of Hepatitis B Virus Gene Expression In Vivo with Short Hairpin RNA Expressed from a Novel Double-Stranded, Bi-Cistronic Adeno-Associated Virus Pseudotype 8 Vector
Dirk Grimm, Konrad L. Streetz, Theresa A. Storm, Hiroyuki Nakai, Anton P. McCaffrey, Zan Huang, Felix H. Salazar, Patricia L. Marion and Mark A. Kay
Mol Ther 9: S141-S142; doi:10.1016/j.ymthe.2004.06.918
372. Passive Immunotherapy for Anthrax Mediated by an Adenovirus Expressing Anti-Protective Antigen Single Chain Antibody
Kazuhiko Kasuya, Julie L. Boyer, Yadi Tan, D. Olivier Alipui, Neil R. Hackett and Ronald G. Crystal
Mol Ther 9: S142-S142; doi:10.1016/j.ymthe.2004.06.315
373. Simian Adenoviral Vector Based-Vaccine Fully Protect Against Ebola Virus Even in the Presence of Pre-Existing Immunity to Human Adenovirus
Gary P. Kobinger, Heinz Feldmann, Yan Zhi, Gregory P. Schumer, Guangping Gao, Frederik Feldmann, Steven Jones and James M. Wilson
Mol Ther 9: S142-S142; doi:10.1016/j.ymthe.2004.06.317
374. Development of a Genetic Vaccine Conferring Protective Immunity Against |[alpha]|-Cobratoxin Following a Single Administration of an Adenovirus Vector Encoding a Modified, Non-Toxic Cobratoxin Variant
Robert G. Pergolizzi, Rachel Dragos, Alexander Ropper, Andre Menez and Ronald G. Crystal
Mol Ther 9: S143-S143; doi:10.1016/j.ymthe.2004.06.319
375. The Function of F12-Vif Mutant in the Context of APOBEC3G/Vif Model
Giuliana Vallanti, Rossella Lupo, Maurizio Federico, Fulvio Mavilio and Chiara Bovolenta
Mol Ther 9: S143-S143; doi:10.1016/j.ymthe.2004.06.320
376. A Metabolically Responsive Insulin Transgene Delivered by AAV2/8 Pseudotyped, Self-Complementary AAV (SC-AAV2/8) Controls Glycemia in STZ-Diabetic Mice
Mirek Kozlowski, Dorota Lyszcowizc, Adam G. Campbell, Darin E. Olson, Janet E. Rubin and Peter M. Thule
Mol Ther 9: S143-S144; doi:10.1016/j.ymthe.2004.06.308
377. Expression of Acid |[alpha]|-Glucosidase in Nonhuman Primate Diaphragm and Peritoneum after Direct In Utero Delivery of Recombinant Adeno-Associated Virus Type 1
Mary B. Rucker, Alice F. Tarantal, Thomas Conlon, Terence R. Flotte and Barry J. Byrne
Mol Ther 9: S144-S144; doi:10.1016/j.ymthe.2004.06.311
378. An AAV Vector-Mediated Micro-Dystrophin Expression in Relatively Small Percentage of Dystrophin-Deficient mdx Myofibers Still Improved the mdx Phenotype Through Compensatory Hypertrophy
Madoka Ikemoto, Madoka Yoshimura, Miki Sakamoto, Yasushi Mochizuki, Katsutoshi Yuasa, Toshifumi Yokota, Yuko Miyagoe-Suzuki and Shin'ichi Takeda
Mol Ther 9: S144-S145; doi:10.1016/j.ymthe.2004.06.312
379. Myogenic Differentiation of Multipotent Adult Progenitor Cells Derived from Bone Marrow and Muscle Tissue
Morayma Reyes, Sheng Li, En Kimura, Leonard Meuse and Jeffrey Chamberlain
Mol Ther 9: S145-S145; doi:10.1016/j.ymthe.2004.06.314
380. Dedifferentiation of Primary Murine Myoblasts Induced by Ectopic Expression of Msx1
Qiang Liu, Wen Liu, Paul Allen and Yaming Wang
Mol Ther 9: S145-S146; doi:10.1016/j.ymthe.2004.06.316
381. Self-Cleaving Multimeric Hammerhead Ribozymes Abolish Mutant Collagen Transcripts In Cellulo and Exhibit Activity In Vivo
Belinda E. Peace, Jane B. Florer, George Y. Wu, Yoel Smicum, Michael W. Kilpatrick, Petros Tsipouras and Richard J. Wenstrup
Mol Ther 9: S146-S146; doi:10.1016/j.ymthe.2004.06.919
382. In Utero Intramuscular Delivery of a High-Capacity Adenoviral Vector Carrying a Full-Length Murine Dystrophin cDNA Provides Functional Benefit and Reassembly of the Dystrophin-Glycoprotein Complex in Hind Limb Muscles of mdx Mice
Daniel P. Reay, Roberto Bilbao, Eric Wu, Terry L. O'Day, Jon F. Watchko and Paula R. Clemens
Mol Ther 9: S146-S146; doi:10.1016/j.ymthe.2004.06.321
383. Cloning of the Minimal Functional Domain of Human LIM Mineralization Protein-3 Able to Induce Bone Mineralization: In Vitro and In Vivo Study
Enrico Pola, Wanda Lattanzi, Wentao Go, Huijie Sun, Kaori Okada, Andrea Gambotto, Carlo A. Logroscino and Paul D. Robbins
Mol Ther 9: S147-S147; doi:10.1016/j.ymthe.2004.06.322
384. Stem Cells Expressing SMAD 8: A Platform for Tendon Regeneration
Gadi Pelled, Andrea Hoffman, Gadi Turgeman, Peter Eberle, Yoram Zilberman, Hadassah Shinar, Keren Keinan-Adamsky, Andreas Winkel, Gil Navon, Gerhard Gross and Dan Gazit
Mol Ther 9: S147-S147; doi:10.1016/j.ymthe.2004.06.325
385. Noggin Gene-Based Therapy Inhibits Cranial Defect Healing in Mice
Gregory M. Cooper, Hairong Peng, Arvydas Usas, Mark P. Mooney and Johnny Huard
Mol Ther 9: S148-S148; doi:10.1016/j.ymthe.2004.06.327
386. Intra-Arterial Adenoviral Mediated |[beta]|2Adrenergic Receptor (AR) Gene Delivery Induces Neoangiogenesis in Rat Ischemic Hindlimb
Guido Iaccarino, Vincenzo Cerullo, Michele Ciccarelli, Gennaro Galasso, Daniela Sorriento, Walter J. Koch, Federico Piscione, Lucio Pastore, Francesco Salvatore and Bruno Trimarco
Mol Ther 9: S148-S148; doi:10.1016/j.ymthe.2004.06.323
387. The Size of Sinusoidal Fenestrae Is a Critical Determinant of Hepatocyte Transduction after Adenoviral Gene Transfer
Joke Lievens, Jan Snoeys, Katrien Vekemans, Sophie Van Linthout, Ronald de Zanger, D|[eacute]|sir|[eacute]| Collen, Eddie Wisse and Bart De Geest
Mol Ther 9: S149-S149; doi:10.1016/j.ymthe.2004.06.326
388. Protection of End-Organ Damage in Stroke-Prone Spontaneously Hypertensive Rats by Intramuscular Injection of AAV Vector Expressing Interleukin-10
Tatsuya Nomoto, Takashi Okada, Kuniko Shimazaki, Toru Yoshioka, Mutsuko Sarukawa, Koichi Takeuchi, Hiroaki Mizukami, Takashi Matsushita, Ken-ichiro Katsura, Keiji Yamamoto, Akihiro Kume, Uichi Ikeda, Shigeo Ookawara, Yasuo Katayama and Keiya Ozawa
Mol Ther 9: S149-S149; doi:10.1016/j.ymthe.2004.06.328
389. Placental Growth Factor (PIGF) Gene Transfer to the Periadventitial Tissue
Shalini Bhardwaj, Himadri Roy, Kari Alitalo and Seppo Yla-Herttuala
Mol Ther 9: S150-S150; doi:10.1016/j.ymthe.2004.06.329
390. eNOS Gene Transfected Endothelial Cells Inhibit Smooth Muscle Cell Proliferation and Platelet Aggregation In Vitro
Guanhua Xue, Jiwei Zhang, Hao Zhang, baigen Zhang and Minli Sun
Mol Ther 9: S150-S150; doi:10.1016/j.ymthe.2004.06.330
391. Targeted Delivery of Adenovirus Expressing eNOS to the Endothelium In Vivo Lowers Blood Pressure in Hypertensive Rats
William H. Miller, M. Julia Brosnan, Delyth Graham, Arlene J. Frater, Keith M. Channon, Sergei M. Danilov, Paul N. Reynolds, Andrew H. Baker and Anna F. Dominiczak
Mol Ther 9: S150-S151; doi:10.1016/j.ymthe.2004.06.332
392. High Intrinsic Expression of Manganese Superoxide Dismutase is a Critical Protective Mechanism Against Oxidative Stress in Human Endothelial Progenitor Cells
Tongrong He, Timothy E. Peterson, Ekhson L. Holmuhamedov, Andre Terzic, Noel M. Caplice, Larry W. Oberley and Zvonimir S. Katusic
Mol Ther 9: S151-S151; doi:10.1016/j.ymthe.2004.06.334
393. rAAV-Mediated Apo a-1 Milano Gene Transfer Results in Significant Inhibition of Atherogenesis
Sarah Hardy, Prediman K. Shah, Svapna Patel, Juliana Yano, Tripathi B. Rajavashisth, K. K. Wong and Saswati Chatterjee
Mol Ther 9: S151-S151; doi:10.1016/j.ymthe.2004.06.336
394. Effective Focal, Homogeneous Gene Transfer after Coronary Infusion of Adenoviruses
Tetsuo Sasano, Kan Kikuchi, Amy McDonald, Kevin Mills, Leah Peller and Kevin Donahue
Mol Ther 9: S151-S152; doi:10.1016/j.ymthe.2004.06.339
395. Beta-Blockers Restrict Maximum Levels of Transgene Expression Elicited by CMV Promoters in Vascular Smooth Muscle Cells
Husein K. Salem, Paul A. Kingston and Anthony M. Heagerty
Mol Ther 9: S152-S152; doi:10.1016/j.ymthe.2004.06.341
396. Factors Affecting Retroviral Gene Transfer to Human CD34+ Cells
Youngtae Hong, Seungshin Yu, Sujeong Kim, Joonggon Kim and Sunyoung Kim
Mol Ther 9: S152-S152; doi:10.1016/j.ymthe.2004.06.331
397. Transduction of Primary Human CD34+ Cells by Self-Inactivating FIV Vectors
Charlene F. Barroga, Mehdi Gasmi, Olivera Marjanovic, Laura Innis and David J. Looney
Mol Ther 9: S152-S153; doi:10.1016/j.ymthe.2004.06.333
398. Transduction of Human Hematopoietic Stem Cells and T-Lymphocytes with RD114-TR-Pseudotyped Lentiviral Vectors
Francesca Di Nunzio, Bianca Piovani, Sabrina Cazzaniga, Chiara Bonini, Francois-Loic Cosset, Fulvio Mavilio and Anna Stornaiuolo
Mol Ther 9: S153-S153; doi:10.1016/j.ymthe.2004.06.338
399. Transduction of Hematopoietic Stem Cells Using Polymer-Concentrated Ecotropic Retrovirus Coupled with In Vivo Selection of Gene-Modified Cells
Douglas W. McMillin, Natalia Landazuri, Bagirath Gangadharan, David Archer, Joseph Le Doux and H. Trent Spencer
Mol Ther 9: S153-S154; doi:10.1016/j.ymthe.2004.06.342
400. Transduction of Human Embryonic Stem Cells with Lentiviral Vectors: Variable Promoter Activity in Pluripotent Cells
Andrew Hinton, Theodore Friedmann and Alberto Hayek
Mol Ther 9: S154-S154; doi:10.1016/j.ymthe.2004.06.347
401. Engineering Retroviral Vectors for Stem Cell Therapies-Overcoming the Effect of Gene Silencing
Gary K. Lee and David V. Schaffer
Mol Ther 9: S154-S154; doi:10.1016/j.ymthe.2004.06.350
402. Retrovirus and Lentivirus Vectors Are Silenced in ES Cells by Dynamic Interplay of Multiple Epigenetic Modifications
Shuyuan Yao, Tanya Sukonnik, Tara Kean, Rikki Bharadwaj, Peter Pasceri and James Ellis
Mol Ther 9: S154-S155; doi:10.1016/j.ymthe.2004.06.354
403. Selective Engraftment of Genetically Modified Hematopoietic Stem Cells by a Truncated Erythropoietin Receptor
Fabrizia Urbinati, Alexis Grande, Francesco Lotti, Giulia Facchini, Giuliana Ferrari and Fulvio Mavilio
Mol Ther 9: S155-S155; doi:10.1016/j.ymthe.2004.06.360
404. Cloning and Expression of Canine O6-Methylguanine|[ndash]|DNA Methyltransferase Fene in Ex Vivo Cultured Cells
Michail M. Zaboikin, Narasimhachar Srinivasakumar, Tatiana N. Zaboikina and Friedrich G. Schuening
Mol Ther 9: S155-S155; doi:10.1016/j.ymthe.2004.06.366
405. Efficient Lentivirus Vector-Mediated Transduction of Neonatal Porcine Islet Cell Clusters: A Powerful Tool for Xenotransplantation Research
Samantha L. Ginn, Wayne J. Hawthorne, Anita T. Patel, Rebecca Stokes, Stacey N. Walters, Philip J. O'Connell, Peter B. Rowe and Ian E. Alexander
Mol Ther 9: S155-S156; doi:10.1016/j.ymthe.2004.06.371
406. Determination of the Most Efficient Vector System for Gene Transduction into Dendritic Cells (DC)
Eigo Satoh, Hua Yan, Xiao-Kang Li, Wataru Sugiura, Naoki Yamamoto, Kenichi Teramoto, Shigeki Arii and Hiromitsu Kimura
Mol Ther 9: S156-S156; doi:10.1016/j.ymthe.2004.06.377
407. Comparison of Transgene Expression Driven from 4 Different Retroviral Long Terminal Repeats
Sujeong Kim, Mi-Dong Kim, Seock Kang, Chang Wan Joo, Haesook An, Karim Lee, Sunyoung Kim and Seung Shin Yu
Mol Ther 9: S156-S156; doi:10.1016/j.ymthe.2004.06.390
408. Developing Lentiviral Vectors for Specific Gene Expression in CD4+ T Cells
Kit L. Shaw, Karen Pepper, Denise Petersen and Donald B. Kohn
Mol Ther 9: S156-S157; doi:10.1016/j.ymthe.2004.06.396
409. In Vivo Comparison of Liver-Specific Enhancer-Promoter Constructs in the Context of Lentiviral Vectors
Tatiana Khakhoulina, Tuan Huy Nguyen, Catherine Fux-Cametti and Didier Trono
Mol Ther 9: S157-S157; doi:10.1016/j.ymthe.2004.06.402
410. Multivalent siRNAs for Combinatorial HIV Gene Therapy
Joseph S. Anderson, Akhil Banerjea, Ming-Jie Li, John Rossi and Ramesh Akkina
Mol Ther 9: S157-S157; doi:10.1016/j.ymthe.2004.06.407
411. Creation of Novel Lentiviral Vectors That Co-Package Anti-HIV Ribozymes with HIV-1
Shuo Gu, James D. Kim and Gerhard Bauer
Mol Ther 9: S157-S158; doi:10.1016/j.ymthe.2004.06.411
412. Cyclosporine Inhibits the Induction of GFP Specific Immune Responses after Transplantation of Lentivirally Transduced GFP Expressing Hematopoietic Stem Cells in Dogs
Karen Beagles, Laura Peterson, Tobias Neff and Hans-Peter Kiem
Mol Ther 9: S158-S158; doi:10.1016/j.ymthe.2004.06.419
413. Development and Characterization of Lentiviral Vectors for Hemophilia Gene Therapy
Lieven Thorrez, Michael Maris, Carol Miao, Nico Van Rooijen, D|[eacute]|sir|[eacute]| Collen and Marinee Chuah Thierry VandenDriessche
Mol Ther 9: S158-S159; doi:10.1016/j.ymthe.2004.06.424
414. Design of an HIV Vector for Site-Specific Gene Insertion
Gilles Michel, Ying Yu and Jiing-Kuan Yee
Mol Ther 9: S159-S159; doi:10.1016/j.ymthe.2004.06.429
415. Conditional Expression of a Suicide Gene by the Telomere Reverse Transcriptase Promoter for Post-Therapeutic Deletion of Insertional Mutagenesis
Richard G. Painter, Nicholas A. Lanson, Zhengmin Jin, Frank Park and Guoshun Wang
Mol Ther 9: S159-S159; doi:10.1016/j.ymthe.2004.06.432
416. Transient Gene Expression by Non-Integrating Lentiviral (NIL) Vectors
Sarah Nightingale, Roger P. Hollis, Catherine Yang, Ingrid Bahner, Karen A. Pepper and Donald B. Kohn
Mol Ther 9: S159-S160; doi:10.1016/j.ymthe.2004.06.435
417. Simultanous Transfer of the p16INK4a and p21Waf1 Tumor Suppressor Genes Plus GFP Mediated by a Novel Polycistronic Retroviral Vector
Lia K. Muschellack, Bryan E. Strauss and Eugenia Costanzi-Strauss
Mol Ther 9: S160-S160; doi:10.1016/j.ymthe.2004.06.437
418. Adaptation of the Wave Bioreactor to Baculoviral Production of AAV Vectors: Scale-Up Considerations
Haifeng Chen, Shangzhen Zhou, Glenn P. Pierce and Peter Colosi
Mol Ther 9: S160-S160; doi:10.1016/j.ymthe.2004.06.335
419. Production of Recombinant Adeno-Associated Virus Type 5 in Insect Cells
Masashi Urabe, Takayo Nakakura, Keiya Ozawa and Robert M. Kotin
Mol Ther 9: S160-S161; doi:10.1016/j.ymthe.2004.06.337
420. Adaptation of Baculovirus System for Large-Scale Production of rAAV Vector Serotypes
Erik Kohlbrenner, George Aslanidi, David R. Knop, Oleg Gorbatyuk, Kevin Nash, Ronald J. Mandel, Nicholas Muzyczka, Barry J. Burns, Richard O. Snyder and Sergei Zolotukhin
Mol Ther 9: S161-S161; doi:10.1016/j.ymthe.2004.06.340
421. Large-Scale Production of AAV and Adenovirus Vectors Using Active Gassing with Large Culture Vessel
Takashi Okada, Tatsuya Nomoto, Toru Yoshioka, Tsuyoshi Ogura, Takashi Matsushita, Hiroaki Mizukami, Akihiro Kume, Villy Nielsen and Keiya Ozawa
Mol Ther 9: S161-S162; doi:10.1016/j.ymthe.2004.06.343
422. Optimization of AAV Vector Production by Transient Transfection
Xiaofei Wang, Sooah Sohr, Floro Cataniag, Fraser Wright and Guang Qu
Mol Ther 9: S162-S162; doi:10.1016/j.ymthe.2004.06.344
423. Isolation of an Adeno-Associated Virus (AAV)-Specific Camelid-Derived Single Chain Antibody Fragment: A Novel Tool for Purification of AAV Vectors of Different Serotypes
Paul P. A. Oranje, Peter Verheesen, Dennis Verbart, Yvonne Mijnsbergen, Hans J. W. Haard, Pim Hermans, Mark R. ten Haaft, Jaap Twisk, Paul A. Dijkhuizen, Wim T. J. M. C. Hermens and Janneke J. M. Meulenberg
Mol Ther 9: S162-S162; doi:10.1016/j.ymthe.2004.06.345
424. Development of a Scalable Column Chromatography-Based Purification Process to Manufacure Empty Capsid-Free AAV Vectors
Guang Qu, Xiaofei Wang, Jac Luna, Sooah Sohr, Floro Cataniag and Fraser J. Wright
Mol Ther 9: S162-S162; doi:10.1016/j.ymthe.2004.06.346
425. Formulation Development for AAV2 Vectors: Identification of Excipients That Inhibit Vector Aggregation
J. Fraser Wright, Tannie Le, Hoc Nguyen, Jurg M. Sommer, Glenn Pierce and Guang Qu
Mol Ther 9: S163-S163; doi:10.1016/j.ymthe.2004.06.356
426. Novel Chromatographic Process for the Purification of Recombinant Adeno-Associated Virus Pseudotypes
Michael Moxley, Donald Fisher, Anthony P. Green and Timothy D. Kierstead
Mol Ther 9: S163-S163; doi:10.1016/j.ymthe.2004.06.359
427. Adipose Tissue as a Novel Target for In Vivo Gene Transfer Using Adeno-Associate Virus (AAV) Vectors
Hiroaki Mizukami, Jun Mimuro, Tsuyoshi Ogura, Takashi Okada, Akihiro Kume, Yoichi Sakata and Keiya Ozawa
Mol Ther 9: S163-S163; doi:10.1016/j.ymthe.2004.06.363
428. Adrenomedullin Gene Delivery Attenuates Renal Damage and Hypertension in Spontaneous Hypertension Rats
Xin Wei, Chunxia Zhao, Jiangang Jiang, Zhenjun Liu and Daowen Wang
Mol Ther 9: S164-S164; doi:10.1016/j.ymthe.2004.06.367
429. Alpha 1 Antitrypsin Gene Delivery for Preventing Type 1 Diabetes in NOD Mice
Yuanqing Lu, Mei Tang, Clive Wasserfall, Young-Kook Choi, Thomas Gardmann, Martha Campbell-Thompson, Mark A. Atkinson and Sihong Song
Mol Ther 9: S164-S164; doi:10.1016/j.ymthe.2004.06.384
430. AAV-Microbead Conjugates for the Enhanced Delivery of AAV-Based Vectors
Samuel J. Farlow, Mark W. Pandori and Takeshi Sano
Mol Ther 9: S164-S164; doi:10.1016/j.ymthe.2004.06.386
431. Selective Upregulation of TGFb1ACT in the Rat Heart To Induce Cardioprotection from Ischemia-Reperfusion Injury
Kui Chen, Yong Liu, Dayuan Li, Paul L. Hermonat and Jawahar L. Mehta
Mol Ther 9: S164-S165; doi:10.1016/j.ymthe.2004.06.391
432. Safety of Administration of AAV2CUhCLN2, a Candidate Treatment for Late Infantile Neuronal Lipofuscinosis to the Brain of Rats and Non-Human Primates
Neil R. Hackett, D. Eugene Redmond Jr., Dolan Sondhi, E. Lela Giannaris, Elizabeth Vassallo, Stephen M. Kaminsky and Ronald G. Crystal
Mol Ther 9: S165-S165; doi:10.1016/j.ymthe.2004.06.395
433. Micro-Utrophin as a Therapeutic Protein in rAAV Mediated Gene Therapy for Duchenne Muscular Dystrophy
Michael J. Blankinship, Paul Gregorevic and Jeffrey S. Chamberlain
Mol Ther 9: S165-S165; doi:10.1016/j.ymthe.2004.06.398
434. Recombinant Adeno-Associated Virus 2 -Mediated Anti-Angiogenic Gene Therapy in a Mouse Model of Intraperitoneal Ovarian Cancer
Tatyana Isayeva, Changchun Ren and Selvarangan Ponnazhagan
Mol Ther 9: S166-S166; doi:10.1016/j.ymthe.2004.06.400
435. Adeno-Associated Virus Vectors Are Able To Restore FALDH Deficiency in Cells of Sjoegren-Larsson Syndrome
Markus Braun-Falco, Stefanie Haug and Hildegard Buning
Mol Ther 9: S166-S166; doi:10.1016/j.ymthe.2004.06.831
436. Recombinant Adeno-Associated Virus Gene Therapy for Cob(I)Alamin Adenosyltransferase Deficiency
Kirsten Elizabeth Erger, Thomas James Conlon, Dietrich Matern, Thomas A. Bobik and Terence R. Flotte
Mol Ther 9: S166-S167; doi:10.1016/j.ymthe.2004.06.832
437. Developing a Mouse Model of the Mitochondrial NARP Syndrome Using AAV-Ribozymes for ATP6
Jennifer A. Bongorno, John Guy and Alfred S. Lewin
Mol Ther 9: S167-S167; doi:10.1016/j.ymthe.2004.06.410
438. In Vitro Studies Towards the Development of a Recombinant Adeno-Associated Virus for the Treatment of Medium-Chain Acyl-CoA Dehydrogenase Deficiency
J. Lawrence Merritt II, Dietrich Matern, Jerry Vockley, Joeseph Huey and David B. Schowalter
Mol Ther 9: S167-S167; doi:10.1016/j.ymthe.2004.06.414
439. Neuronal Membrane Specific Binding Peptides Isolated Via Phage Display Biopanning Against Trisialogangliosides
James K. Liu, Qingshan Teng, Diana Tanase, Mary Moses, Ajit Krishnaney and Nicholas M. Boulis
Mol Ther 9: S167-S168; doi:10.1016/j.ymthe.2004.06.417
440. The Multidrug Resistant Phenotype in Tumor Cells Facilitates Adenoviral Replication: New Concepts for Oncolytic Vector Development
Alexandra Bernshausen, Gabriel Glockzin, Klaus Mantwill, Hans-Dieter Royer, Karsten Juerchott, Bernd Gaensbacher and Per Sonne Holm
Mol Ther 9: S168-S168; doi:10.1016/j.ymthe.2004.06.348
441. Conditional Replication Competent Adenovirus Ad-mTERT-|[Delta]|19 Driven by Human Telomerase Promoter Replicates and Elicits Cytopathic Effect Specifically in Cancer Cells
Eunhee Kim, Taeyoung Koo, Dong Hyun Ko, Yoon A. Kang, Joo-Hang Kim and Chae-Ok Yun
Mol Ther 9: S168-S168; doi:10.1016/j.ymthe.2004.06.351
442. Novel cox-2 Driven Infectivity Enhanced CRAds for Treatment of Ovarian Cancer
Gerd J. Bauerschmitz, Anna Kanerva, Masato Yamamoto, Dirk Nettelbeck, Tanja Hakkarainen, Peter Dall, David T. Curiel and Akseli Hemminki
Mol Ther 9: S168-S169; doi:10.1016/j.ymthe.2004.06.358
443. Incorporating the Survivin Promoter in an Infectivity Enhanced CRAd-Analysis of Oncolysis in Five Different Cancer Cell Lines
Zeng B. Zhu, Sharmila K. Makhija, Baogen Lu, Minghui Wang, Angel A. Rivera, Gene P. Siegal, Ronald D. Alvarez and David T. Curiel
Mol Ther 9: S169-S169; doi:10.1016/j.ymthe.2004.06.361
444. ADP-Overexpressing Adenovirus Elicits Enhanced Cytopathic Effect by Induction of Apoptosis
Eunhee Kim, Taeyoung Koo, Dae-Bong Kang, Il-Kyu Choi, Joo-Hyuk Sohn, Chae-Ok Yun and Joo-Hang Kim
Mol Ther 9: S169-S169; doi:10.1016/j.ymthe.2004.06.365
445. CG5757, an Oncolytic Adenovirus for the Treatment of Retinoblstoma (Rb) Pathway-Defective and Telomerase-Positive Cancers
Yuanhao Li, Natalie Nguyen, Derek Ko, Melinda VanRoey, Gail Colben, Neeraja Idamakanti, Orlena Tam, Trini Arroyo, P.Seshidhar Reddy, Peter Working and De-Chao Yu
Mol Ther 9: S169-S170; doi:10.1016/j.ymthe.2004.06.375
446. A Rapid, Efficient and Feasible Method for Constructing Conditionally-Replicating Adenoviral Vectors that Specifically Target Cancer Cells with Multiple Factors
Satoshi Nagano, Yohiteru Murofushi, Setsuro Komiya and Ken-ichiro Kosai
Mol Ther 9: S170-S170; doi:10.1016/j.ymthe.2004.06.382
447. Replication-Competent Oncolytic Adenovirus Vectors That Express TRAIL and Over-Express ADP
Baoling Ying, Peter Krajcsi, Ann E. Tollefson, Jacqueline F. Spencer, Konstantin Doronin, Drew L. Lichtenstein and William S. M. Wold
Mol Ther 9: S170-S171; doi:10.1016/j.ymthe.2004.06.385
448. Armed Oncolytic Adenovirus with an Antiangiogenic Gene, sflt-1: A Novel Effective Antitumor Approach
Zilai Zhang, Jinhui Wang, Weiguo Zou, Binghua Li, Zifei Pei, Jinfa Gu, Cheng Qian and Xinyuan Liu
Mol Ther 9: S171-S171; doi:10.1016/j.ymthe.2004.06.388
449. Evaluation of New Generation of Prostate Specific Replication Competent Adenoviruses with E1A-AR Chimera
Ying Li, Chien-lun Chen, Aarup Kubal, Qinghua Xia and Ronald Rodriguez
Mol Ther 9: S171-S171; doi:10.1016/j.ymthe.2004.06.393
450. Anti-CD22 Immunolipoplexes Enhance Transduction of Adenovirus in B Lymphoma Cells Independent on Adenovirus' Receptor but do not Enhance the Cytotoxicity of Oncolytic Adenovirus
Yaohe, H. Pen, Jennelle, Gunnel, Shao-an, Beverly E. Grriffin and Nick R. Lemoine
Mol Ther 9: S171-S172; doi:10.1016/j.ymthe.2004.06.397
451. A Novel Cell Cycle Dependent Conditionally Replicating Adenovirus Vector for Targeting a Broad-Spectrum of Cancer
Atique Ahmed, Jian Qiao, Jesus Moreno and Richard G. Vile
Mol Ther 9: S172-S172; doi:10.1016/j.ymthe.2004.06.401
452. Adenoviral Gene Therapy Using CRAd Targeted to Cells with Hyperactive Wnt/|[beta]|-Catenin Signaling
Phillip H. Abbosh and Kenneth P. Nephew
Mol Ther 9: S172-S172; doi:10.1016/j.ymthe.2004.06.404
453. Reproductive Safety Evaluation and Quantification of Adenoviral Vectors in the Mouse
Gyu Seek Rhee, Hyun Joo Lee, Soon Sun Kim, Seung Jun Kwack, Rhee Da Lee, Ji Hyun Seok, Soo Yeong Chae, Jae Woo Kim, Young Hyuk Won, Seung Hoon Lee and Kui Lea Park
Mol Ther 9: S172-S173; doi:10.1016/j.ymthe.2004.06.406
454. Evaluation of Polyethylene Glycol (PEG) Modification of Adenoviral Vectors to Reduce Innate Immune Response and Increase Vector Persistence
Hoyin S. Mok and Michael A. Barry
Mol Ther 9: S173-S173; doi:10.1016/j.ymthe.2004.06.409
455. Neutrophils Interact with Adenovirus Vectors Via the |[beta]|2-Integrin CD11b
Daniel A. Muruve and Matthew J. Cotter
Mol Ther 9: S173-S173; doi:10.1016/j.ymthe.2004.06.413
456. A Comparison of Adenoviral-Mediated Gene Transfer in Human and Mouse Dendritic Cells
Brian J. Morrison, Yoshio Sakai, John E. Janik and John C. Morris
Mol Ther 9: S173-S174; doi:10.1016/j.ymthe.2004.06.416
457. Fibronectin Peptide Reduces the Immune Response to Adenovirus and Enhances Transgene Expression
Takako Miyamae, Anthony D. Marinov, Sylvie Fabre, David C. Wilson, Tomoyuki Imagawa, Bruce C. Trapnell, Gregory P. Boivin and Raphael Hirsch
Mol Ther 9: S174-S174; doi:10.1016/j.ymthe.2004.06.418
458. Efficient Transduction of Human and Murine Cells and Circumvention of Preexisting Human Adenoviral Immunity by Porcine Adenoviral Vectors
Dinesh Singh and Suresh K. Mittal
Mol Ther 9: S174-S174; doi:10.1016/j.ymthe.2004.06.421
459. Immune System Regulation of Transgene Expression in the Brain 1: Systemically Activated Immune Responses Silence Adenoviral Vector-Encoded Transgene Expression in the Brain Through Both Non-Cytolytic, and Cytotoxic Mechanisms
Carlos Barcia, Clare Thomas, Jeff Zirger, Weidong Xiong, Olivier Boyer, David Klatzmann, Maria G. Castro and Pedro R. Lowenstein
Mol Ther 9: S174-S175; doi:10.1016/j.ymthe.2004.06.423
460. Immunogenicity of E2b-Deleted Adenoviral Vectors Compared with First Generation Vectors
Jie Mi, Shannon Barker, Leonard Meuse, Shanna Sawatzki, Dennis Hartigan-O'Connor and Jeffrey S. Chamberlain
Mol Ther 9: S175-S175; doi:10.1016/j.ymthe.2004.06.426
461. In Vivo Immunogenicity of Adenoviral Vectors with Improved Dendritic Cell Tropism
Catherine Hsu, Megan M. Boysen, Phyllis D. Frosst and Dan J. Von Seggern
Mol Ther 9: S175-S175; doi:10.1016/j.ymthe.2004.06.428
462. Toxicity Related to Predosing with Adenoviral Vectors Carrying Lac-Z or Dominant Negative IKK2 Transgenes
Viraj P. Mane, Racel Cela, Nicola Brunetti, Phil Ng and Brendan Lee
Mol Ther 9: S175-S176; doi:10.1016/j.ymthe.2004.06.431
463. Conditionally Replicative Adenovirus Expressing Degradation-Resistant p53 for Enhanced Oncolysis of MDM2 Overexpressing Cancers
Victor W. van Beusechem, Petra B. van den Doel and Winald R. Gerritsen
Mol Ther 9: S176-S176; doi:10.1016/j.ymthe.2004.06.433
464. Severe Pulmonary Pathology after Intravenous Administration of Adenovirus Vectors in Cirrhotic Rats
Jeffrey S. Smith, Jie Tian, Jay N. Lozier and Andrew P. Byrnes
Mol Ther 9: S176-S176; doi:10.1016/j.ymthe.2004.06.434
465. Delivery of NF-|[kappa]||[beta]| Decoy Related Oligodeoxynucleotides Reduces Pro-Inflammatory Cytokine Responses Associated with Plasmid DNA/Lipid Mediated Gene Transfer to Murine Lungs
Anusha Varathalingam, Ian A. Pringle, Seng H. Cheng, Deborah R. Gill and Stephen C. Hyde
Mol Ther 9: S177-S177; doi:10.1016/j.ymthe.2004.06.349
466. Downregulation of ATF2 Desensitizes Oral Squamous Cell Carcinoma to Apoptosis
Sleiman N. Razzouk, Svetlana M. Dolgilevich and Dianne C. Duffey
Mol Ther 9: S177-S177; doi:10.1016/j.ymthe.2004.06.352
467. Cationic Liposome-Based Delivery of DNA Modulating Enzymes to Specifically Regulate Gene Expression in Carcinoma Derived Cell Lines
Pamela M. J. McLaughlin, Monika Trzpis, Ieneke T. F. van der Gun, Martin C. Harmsen and Marcel H. J. Ruiters
Mol Ther 9: S177-S178; doi:10.1016/j.ymthe.2004.06.353
468. Tissue Factor as a Link Between Wounding and Tissue Repair
Jiang Chen, Michael Kasper, Katsumi Nakagawa, Lin Bai, Wu Gang, Youming Zhang, Per M. Humpert, Martin Andrassy, Thomas Luther, Stephan Schiekofer, Baosheng Chen, Michael Morcos, Andreas Hamann, David M. Stern, Peter P. Nawroth and Angelika Bierhaus
Mol Ther 9: S178-S178; doi:10.1016/j.ymthe.2004.06.355
469. Improved Transfection with Mixtures of Cationic Lipids: Application to Human Umbilical Artery Endothelial Cells (HUAEC)
Li Wang and Robert C. MacDonald
Mol Ther 9: S178-S178; doi:10.1016/j.ymthe.2004.06.357
470. Enhanced Transposition Activities of Mutant Sleeping Beauty Transposases
Bradley S. Fletcher, James Baus and Arne Heggestad
Mol Ther 9: S178-S179; doi:10.1016/j.ymthe.2004.06.362
471. Efficient Non-Viral Vectorisation of siRNA in the Brains of Newborn Mice
Zahra Hassani, Gregory Lemkine, Patrick Erbacher, Carine Giovannangeli, Jean Paul Behr and Barbara A. Demeneix
Mol Ther 9: S179-S179; doi:10.1016/j.ymthe.2004.06.364
472. In Vitro and In Vivo Gene Expression Mediated by Cationic Sendai F/HN Virosomes
Hong Sung Kim, Keun Sik Kim, Myung Min Choi, Ji Eun Lee and Yong Serk Park
Mol Ther 9: S179-S179; doi:10.1016/j.ymthe.2004.06.368
473. Magnetofection to Enhance Airway Gene Transfer
Stefania Xenariou, Uta Griesenbach, Stefano Ferrari, Phillip Dean, Ron Scheule, Seng Cheng, Duncan Geddes, Christian Plank and Eric Alton
Mol Ther 9: S180-S180; doi:10.1016/j.ymthe.2004.06.369
474. The Barrier to Liposomal Transfection is Enhanced by DNASES Lacking Lysosomal-Targetting Glycosylation
Andrew Wilber, Gary Armour and Michael C. Schneider
Mol Ther 9: S180-S180; doi:10.1016/j.ymthe.2004.06.370
475. Anionic Polyethyleneglycol Lipids Added to Cationic Lipoplexes Increase Their Plasmatic Circulation Time
C|[eacute]|line Nicolazzi, Nathalie Mignet, Nathalia Dela Figuera, Mamonjy Cadet, Raoul Torero Ibad, Johanne Seguin, Daniel Scherman and Michel Bessodes
Mol Ther 9: S180-S181; doi:10.1016/j.ymthe.2004.06.372
476. Human Mesenchymal Stem Cells Genetically Modified To Express High Levels of Erythropoietin Through Transfer of an Artificial Chromosome Engineered Using the ACE System
Sandra Vanderbyl, Neil MacDonald, Tom Stodola, Adele Telenius, Sandra Stewart, Harry C. Ledebur Jr. and Carl F. Perez
Mol Ther 9: S181-S181; doi:10.1016/j.ymthe.2004.06.373
477. New pyridinium cationic lipids for gene delivery synthesized via pyrylium salts
Marc A. Ilies, Betty H. Johnson, William A. Seitz, Edward L. Ezell, Aaron Miller, E. Brad Thompson and Alexandru T. Balaban
Mol Ther 9: S181-S181; doi:10.1016/j.ymthe.2004.06.374
478. Preinjection of free DiC14-amidine liposome and dexamethasone synergistically enhance the intravenous transfection efficiency of cationic lipid/DNA lipoplex
Caroline Lonez, Jean-Marie Ruysschaert and Abdelatif Elouahabi
Mol Ther 9: S181-S181; doi:10.1016/j.ymthe.2004.06.376
479. KLN-47, a safe lipophosphoramide reagent, efficiently transfects (>100 kb) large plasmids into epithelial cells
Tristan Y. Montier, Laura Hyndman, A. Christopher Boyd, Catherine Payne, Ann Doherty, Pascal Delepine, Claude Ferec and David Porteous
Mol Ther 9: S182-S182; doi:10.1016/j.ymthe.2004.06.378
480. Magnetofection to enhance transfection efficiency of large genomic context vectors in vitro
Stefania Xenariou, Uta Griesenbach, Ramsay Bowden, Elizabeth Hillery, Ann Doherty, Duncan Geddes, David Porteous, Christian Plank, Eric Alton and A. Christopher Boyd
Mol Ther 9: S182-S182; doi:10.1016/j.ymthe.2004.06.379
481. Efficient gene transfer into human epithelial cell lines using glycosylated cationic carriers and neutral glycosylated co-lipids
Tristan Montier, Pascal Delepine, Thierry Benvegnu, Daniel Plusquellec and Claude Ferec
Mol Ther 9: S182-S183; doi:10.1016/j.ymthe.2004.06.380
482. Design and production of peptide transfecting agents using recombinant TAT-Mu-NLS sequences
Y. Ramadas, Madhusudhana N. Rao and Vijaya Gopal
Mol Ther 9: S183-S183; doi:10.1016/j.ymthe.2004.06.381
483. Acoustically active liposomes for oligonucleotide/drug encapsulation; delivery agents with capacity for ultrasound-triggered release
Shao-Ling Huang, David D. McPherson and Robert C. MacDanold
Mol Ther 9: S183-S184; doi:10.1016/j.ymthe.2004.06.383
484. Longevity of Expression Following Liposome-Mediated Gene Transfer
Wendy E. Walker and Andy D. Miller
Mol Ther 9: S184-S184; doi:10.1016/j.ymthe.2004.06.387
485. Marked transfection enhancement by the DPL (DNA/peptide/liposomes) trimeric complex
Jong-Gu Park and Ik-Jae Moon
Mol Ther 9: S184-S184; doi:10.1016/j.ymthe.2004.06.389
486. Plasmid DNA constructs expressing SARS-CoV antigens are immunogenic in mice and rabbits
Adrian Vilalta, Michal Margalith, Tom Evans, David C. Kaslow and Peter Hobart
Mol Ther 9: S184-S184; doi:10.1016/j.ymthe.2004.06.392
487. Influence surface modification of lipoplexes on the pharmacokinetics of non-viral vectors for gene delivery
Eric Perouzel, Annabelle Caussin, Kristina Ulrich, Andrew D. Miller, Charles Coutelle, Michael Keller and Michael Jorgensen
Mol Ther 9: S185-S185; doi:10.1016/j.ymthe.2004.06.394
488. Adenovirus-mediated delivery of ADAM10, a novel candidate gene for COPD, results in emphysematous changes in the mouse lung
Hiroki Saitoh, Adriana Heguy, Timothy P. O'Connor, Ben-Gary Harvey, Philip L. Leopold, Neil R. Hackett, Adam Cieciuch and Ronald G. Crystal
Mol Ther 9: S185-S185; doi:10.1016/j.ymthe.2004.06.1017
489. Comparison of AAV2 and AAV2/5 CFTR vectors in the lungs of cynomolgus macaques
Keith L. Munson, Laurie M. Tatalick, Carolina I. Smith, Anne C. Fischer, Pervin Anklesaria, Barrie J. Carter and William B. Guggino
Mol Ther 9: S185-S186; doi:10.1016/j.ymthe.2004.06.399
490. Long Term Expression and Biodistribution of HIV Vector Pseudotyped with Deletion Mutant of the Ebola Envelope Glycoprotein Following Instillation in Airway of Nonhuman Primates
Gregory P. Schumer, Gary P. Kobinger, Maria F. Medina, Daniel J. Weiner and James M. Wilson
Mol Ther 9: S186-S186; doi:10.1016/j.ymthe.2004.06.403
491. Improved Apical Airway Epithelia Targeting Properties of FIV Vector Pseudotyped with Envelopes from LCMV
Douglas E. Dylla, Melissa A. Hickey, Daniel E. Michele, Beverly L. Davidson, Kevin P. Campbell and Paul B. McCray Jr.
Mol Ther 9: S186-S186; doi:10.1016/j.ymthe.2004.06.405
492. Characterization of the Apical Transduction of Well-Differentiated Mouse Tracheal Cultures by an Equine Lentivirus Pseudotyped with Avian Influenza Coat Proteins
Tristan R. McKay, Manij Patel, Angela M. Giddings, Raymond J. Pickles and John C. Olsen
Mol Ther 9: S186-S187; doi:10.1016/j.ymthe.2004.06.408
493. Enhanced Transgene Transfer and Expression by an Endobronchially Delivered Pseudotyped AAV2/5 Vector
Anne C. Fischer, Carolina I. Smith, Terence R. Flotte and William B. Guggino
Mol Ther 9: S187-S187; doi:10.1016/j.ymthe.2004.06.412
494. Topical Delivery of mRNA to the Murine Lung and Nasal Epithelium
Hazel Painter, Stephanie G. Sumner-Jones, Seng H. Cheng, Steve C. Hyde and Deborah R. Gill
Mol Ther 9: S187-S187; doi:10.1016/j.ymthe.2004.06.415
495. Efficient In Vivo Transduction of Mouse Airway Epithelial Cells by the Simian Immunodeficiency Virus Vector Pseudotyped with Sendai Virus F and HN Proteins
Hisao Shirohzu, Katsuhisa Mitomo, Toshiaki Tabata, Uta Griesenbach, Steve C. Hyde, Eric W. Alton, Yasuji Ueda and Mamoru Hasegawa
Mol Ther 9: S188-S188; doi:10.1016/j.ymthe.2004.06.420
496. Recombinant Sendai Virus Vector to Evaluate Vector Distribution in a Large Animal Model of Lung Gene Transfer
Gerry McLachlan, Uta Griesenbach, Toshi Owaki, Liz Hillery, John Williams, Zhu Yafeng, Chris Boyd, Deborah Gill, Mamoru Hasegawa, Eric W. F. W. Alton and David Collie
Mol Ther 9: S188-S188; doi:10.1016/j.ymthe.2004.06.422
497. Ciliated-Cell Specific Expression of a Transgene by a Self-Inactivating Murine Retrovirus in Human Bronchial Epithelial Cells
Lawrence E. Ostrowski, Kerri A. Kendrick, Angela M. Giddings and John C. Olsen
Mol Ther 9: S188-S189; doi:10.1016/j.ymthe.2004.06.425
498. Targeted Gene Transfer to Lung Airway Epithelium Using Plasmid or Adenoviral Vectors Formulated with an Anti-Inflammatory Dexamethasone-Spermine Conjugate
Amber Price, Maria Limberis, Jeffrey Gruneich, James M. Wilson and Scott L. Diamond
Mol Ther 9: S189-S189; doi:10.1016/j.ymthe.2004.06.427
499. Inhibition of Non-Small Cell Lung Cancer by Silencing EGFR with RNAi
Ming Wei, M. Zhang, X. Zhang, J. Chen, L. Gao, J. Hu, Q. Y. Hong, M. West and C. X. Bai
Mol Ther 9: S189-S190; doi:10.1016/j.ymthe.2004.06.430
500. Local and systemic inhibition of lung tumor growth after liposome mediated mda-7/IL-24 gene delivery
Rajagopal Ramesh, Isao Ito, Ryo Miyahara, Yuji Saito, Zheng Wu, Abner M. Mhashilkar, Deborah R. Wilson, Cynthia D. Branch, Sunil Chada and Jack A. Roth
Mol Ther 9: S190-S190; doi:10.1016/j.ymthe.2004.06.436
501. Aerosols of compacted DNA nanoparticles retain structural integrity and biological activity
Sharon M. Oette, Christopher R. Gedeon, Tomasz H. Kowalczyk, Tamara L. Fink, Susannah L. Hyatt, Robert C. Moen and Mark J. Cooper
Mol Ther 9: S190-S190; doi:10.1016/j.ymthe.2004.06.438
502. Formulation of adenoviral vectors with inhibitors of mucociliary clearance enhances gene transfer to airway epithelia in vivo
Patrick L. Sinn, Ankur Shah, Maureen D. Donovan and Paul B. McCray Jr
Mol Ther 9: S190-S191; doi:10.1016/j.ymthe.2004.06.439
503. Gene transfer strategies for pulmonary hypertension
Larry G. Johnson, Manij Patel, Miriam K. Vanhook and John C. Olsen
Mol Ther 9: S191-S191; doi:10.1016/j.ymthe.2004.06.440
504. Gene Transfection into Fetal Sheep Airway Epithelium Using Cationic BGTC/DOPE Liposomes
Noufissa Oudrhiri, Dominique Luton, Pascal De Lagausie, Abderrahim Aissaoui, Michelle Hauchecorne, Michel Peuchmaur, Jean-Pierre Vigneron, Jean-Francois Oury, Yves Aigrain, Jean-Marie Lehn and Pierre Lehn
Mol Ther 9: S191-S191; doi:10.1016/j.ymthe.2004.06.441
505. Effective Transgene Expression in the Murine Lung Using Compacted DNA Nanoparticles Formulated with Plasmid DNAs of 5, 10, and 20 kbp
Tamara L. Fink, Patrick J. Klepcyk, Sharon M. Oette, Christopher R. Gedeon, Susannah L. Hyatt, Tomasz H. Kowalczyk, Robert C. Moen and Mark J. Cooper
Mol Ther 9: S192-S192; doi:10.1016/j.ymthe.2004.06.442
506. LPS-Induced Lung Inflammation and Bronchial Hyperreactivity: Effects of Murine IL-10 When Injected in the Airways or Generated in the Circulation after Muscle Electrotransfer of Murine IL-10 Encoding Plasmid
Virginie Deleuze, Jean Lefort, Michel-Francis Bureau, Daniel Scherman and B. Boris Vargaftig
Mol Ther 9: S192-S192; doi:10.1016/j.ymthe.2004.06.443
507. Down-Regulation of the Epithelial Sodium Channel ENaC through Antisense Oligonucleotides
Uta Griesenbach, Sara Escudero Garcia, Chris Kitson, Raymond Farley, Charanjit Singh, Hazel Painter, Rebecca L. Smith, Ron Scheule, Seng Cheng, Mark Edbrooke, Steve Hyde, Duncan M. Geddes and Eric W. F. W. Alton
Mol Ther 9: S192-S193; doi:10.1016/j.ymthe.2004.06.445
508. AAV2 and AAV6 Serology in Normal and Cystic Fibrosis Populations
Christine L. Halbert, A. Dusty Miller, Ron L. Gibson and Moira L. Aitken
Mol Ther 9: S193-S193; doi:10.1016/j.ymthe.2004.06.446
509. Non-Viral Gene Delivery in the Murine Nasal Epithelium by Hypotonic Shock
Jerome L. Lemoine and Leaf Huang
Mol Ther 9: S193-S193; doi:10.1016/j.ymthe.2004.06.448
510. In Vivo-Gene Expression of Aerosolized PEI Gene Vector Complexes Is Solvent-Dependent
Carsten Rudolph, Aurora Ortiz, Ulrike Schillinger, Christian Plank and Joseph Rosenecker
Mol Ther 9: S193-S194; doi:10.1016/j.ymthe.2004.06.449
511. Improvement of Aerosol Delivery of Polyethylenimine (PEI)-Based Gene Vectors to the Lungs of Mice
Carsten Rudolph, Aurora Ortiz, Ulrike Schillinger, Jurgen Jauernig, Christian Plank and Joseph Rosenecker
Mol Ther 9: S194-S194; doi:10.1016/j.ymthe.2004.06.451
512. Electroporation-Mediated Gene Transfer of Human Hepatocyte Growth Factor Reduces Bleomycin-Induced Pulmonary Fibrosis in Rats
Amiq Gazdhar, Patrick Fachinger, Jaroslaw Pierog, Steven Hyde, Mathias Gugger, Ralph Schmid and Thomas Geiser
Mol Ther 9: S194-S194; doi:10.1016/j.ymthe.2004.06.452
513. Prevention of Irradiation-Induced Organizing Alveolitis by Inhalation Delivery of Manganese Superoxide Dismutase-Plasmid/Liposome (MnSOD-PL) Complexes to Mouse Lung
Matthew Carpenter, Anurag Agarwal, Suhua Nie, Lauren Hricisak, Michael W. Epperly and Joel S. Greenberger
Mol Ther 9: S194-S195; doi:10.1016/j.ymthe.2004.06.453
514. Potential of Bone Marrow Mesenchymal Stem Cells for Cystic Fibrosis Therapy
Guoshun Wang, Bruce A. Bunnell, Richard G. Painter, Susan Tom, Nicholas A. Lanson, Jeffery L. Spees, Donna Bertucci, Daniel J. Weiss, Vincent G. Valentine, Darwin J. Prockop and Jay K. Kolls
Mol Ther 9: S195-S195; doi:10.1016/j.ymthe.2004.06.455
515. Mutation Independent Knockdown of Mutant mRNA by RNA Interference and Replacement by mRNA with Knockdown-Resistant Codons
Rajendra Kumar-Singh, Erin Binkley and Siobhan Cashman
Mol Ther 9: S195-S196; doi:10.1016/j.ymthe.2004.06.444
516. Vestibular Hair Cell Regeneration and Re-Establishment of Balance Function Induced by Math1 Gene Delivery
Hinrich Staecker, Mark Praetorius, Kim Baker and Douglas E. Brough
Mol Ther 9: S196-S196; doi:10.1016/j.ymthe.2004.06.447
517. Prevention of Onset of Parkinson's Disease by In Vivo Gene Transfer of Human Hepatocyte Growth Factor in Primate Model: A Model of Gene Therapy for Parkinson's Disease
Hiromi Koike, Akihiko Ishida, Munehisa Shimamura, Naoyuki Sato, Naruya Tomita, Yasufumi Kaneda and Ryuichi Morishita
Mol Ther 9: S196-S196; doi:10.1016/j.ymthe.2004.06.450
518. Long-term lentiviral vector-mediated transgene expression in neural progenitor cells following implantation into the injured rat spinal cord
Bas Blits, Caroline V. Caperton, Brandon M. Kitay, Gaelle Corrales and Mary Bunge
Mol Ther 9: S196-S196; doi:10.1016/j.ymthe.2004.06.454
519. Minimally invasive strategies for administration of genetically-modified glia to the contused spinal cord
Damien D. Pearse, Bas Blits, Mary B. Bunge, Patrick M. Wood, Andre R. Sanchez, Andres Hurtado, Enrique P. Lopez and Oudega Martin
Mol Ther 9: S197-S197; doi:10.1016/j.ymthe.2004.06.456
520. Canine neural progenitor cells: phenotypic markers in vitro and in situ
Raquel M. Walton, Deborah J. Watson and John H. Wolfe
Mol Ther 9: S197-S197; doi:10.1016/j.ymthe.2004.06.460
521. Helper-dependent adenovirus with gene switch regulation may provide an optimal vector of therapeutic gene delivery for treatment of Parkinson's disease
Q. Chen, Y. He, X. Q. Yuan, P. Ng, P. Yotnda, Y. Long, E. C. Lai and K. Yang
Mol Ther 9: S197-S198; doi:10.1016/j.ymthe.2004.06.462
522. Increased expression of OCT4, SOX2 and FGF4 genes following injection of embryonic stem cell into damaged murine brain
Anand S. Srivastava, Steve Shenouda, Mohamed E. Moustafa and Ewa Carrier
Mol Ther 9: S198-S198; doi:10.1016/j.ymthe.2004.06.464
523. Inhibition of retinal neovascularization by intraocular gene delivery of soluble VEGF receptors
Abraham Scaria, Peter Pechan, Michael Lukason, Hillard Rubin and Samuel Wadsworth
Mol Ther 9: S198-S198; doi:10.1016/j.ymthe.2004.06.465
524. Adenovirus-mediated silencing of Huntingtin expression by hsiRNA
Bin Huang and Stefan Kochanek
Mol Ther 9: S198-S199; doi:10.1016/j.ymthe.2004.06.468
525. Therapy for Alzheimer's disease by neprilysin gene transfer
Robert A. Marr, Edward Rockenstien, Mark S. Kindy, Louis B. Hersh, Fred H. Gage, Eliezer Masliah and Inder M. Verma
Mol Ther 9: S199-S199; doi:10.1016/j.ymthe.2004.06.470
526. A new mouse reporter strain with nuclear-localized lacZ expression allows reliable detection of transplanted and donor-derived cells
Pei-Rong Wang, Daniel G. Miller, George Vassilopoulos and David W. Russell
Mol Ther 9: S199-S199; doi:10.1016/j.ymthe.2004.06.472
527. CERE-110, an AAV2-based vector to deliver NGF, provides trophic activity to basal forebrain cholinergic neurons in rats and cynomolgous monkeys
Kathie M. Bishop, Katrin Hofer, Denise Rius, Arpesh Mehta, Shokry Lawandry, Lamar Brown, Brian Kruegel, Mehdi Gasmi, Mark Tuszynski and Raymond T. Bartus
Mol Ther 9: S199-S200; doi:10.1016/j.ymthe.2004.06.473
528. VEGF gene therapy with retrogradely transported lentivirus prolongs survival in mouse ALS model
Mimoun Azzouz, Thanh Le, Scott G. Ralph, Fraser Wilkes, Arthur H. Burghes, Susan M. Kingsman, Kyriacous A. Mitrophanous and Nicholas D. Mazarakis
Mol Ther 9: S200-S200; doi:10.1016/j.ymthe.2004.06.474
529. rAAV mediated parkin expression confers some protection in the rat 6-OHDA lesion model
Fredric P. Manfredsson, Alfred S. Lewin and Ronald J. Mandel
Mol Ther 9: S200-S200; doi:10.1016/j.ymthe.2004.06.476
530. Spinal interleukin-10 (IL-10) gene therapy using viral and non-viral vectors controls inflammatory- and chronic constriction injury-induced pain states in rats
Erin D. Milligan, Raymond A. Chavez, Stephen J. Langer, Evan M. Sloane, Maru Chacur, Julie L. Wieseler-Frank, Matthew G. Frank, Terrence R. Flotte, Pedro Cruz, Leslie Leinwand, Jennifer A. Shumilla, John R. Forsayeth, Steven F. Maier and Linda R. Watkins
Mol Ther 9: S200-S201; doi:10.1016/j.ymthe.2004.06.477
531. Activation of VEGF by Engineered Zinc Finger Transcriptional Activators: A Novel Therapeutic Approach to Diabetic Neuropathy
Carolyn L. Dent, Gabriel Lau, Edward J. Rebar, Lei Zhang, YaLi Lee, Andrew C. Jamieson, Casey C. Case, Tyler Martin and Philip D. Gregory
Mol Ther 9: S201-S201; doi:10.1016/j.ymthe.2004.06.478
532. Cervical Spinal Cord Delivery of a Lentiviral Vector in SOD-1 Transgenic Mice
Diana Tanase, Qingshan Teng, Ajit A. Krishnaney, James K. Liu, Mary E. Garrity-Moses, Nicholas Mazarakis, Lucy E. Walmsley, Mimoun Azzouz and Nicholas M. Boulis
Mol Ther 9: S201-S201; doi:10.1016/j.ymthe.2004.06.479
533. In Vitro and In Vivo Expression of Modified Mouse Galactosylceramidase in the Twitcher Mouse Model of Krabbe Disease
James Cronin, Xian-Yang Zhang and Jacob Reiser
Mol Ther 9: S201-S201; doi:10.1016/j.ymthe.2004.06.481
534. Recombinant adeno-associated virus serotype 1 vector-mediated transduction within the murine hippocampus
Chuansong Wang and Thomas J. Sferra
Mol Ther 9: S202-S202; doi:10.1016/j.ymthe.2004.06.658
535. Efficient transduction of rat spinal cord cells in vitro and in vivo using neuron-specific and non-specific lentiviral vectors
Tetsuya Nejime, Atsushi Miyanohara, Osamu Kakinohana and Martin Marsala
Mol Ther 9: S202-S202; doi:10.1016/j.ymthe.2004.06.659
536. Design and production of an AAV2 vector encoding a chimeric cDNA allowing efficient secretion of functional human neurturin from human cells
Anthony Ramirez, Junshan Hao, Eli Kethchum, Kevin Kwok, Dominick Vacante, Raymond Bartus and Mehdi Gasmi
Mol Ther 9: S202-S203; doi:10.1016/j.ymthe.2004.06.661
537. Further characterisation of myo-neurospheres
Simon P. Quenneville, Marie-Eve Ducharme, Joel Rousseau, Alain Garnier and Jacques P. Tremblay
Mol Ther 9: S203-S203; doi:10.1016/j.ymthe.2004.06.663
538. Functional correction of A-T cells by ATM gene expression mediated by HSV amplicon vector after the ionizing radiation or under oxidative stress condition
Ryan Manuszak, Rodney Shackelford, Charles J. Link and Suming Wang
Mol Ther 9: S203-S203; doi:10.1016/j.ymthe.2004.06.665
539. Biodistribution and safety profile of CERE-110 (AAV2-NGF) delivered to the rodent brain
Mark Landers, Melissa Austin, Kevin Kwok, Eli Ketchum, Richard Lin, Leo Manlapaz, Arpesh Mehta, Javier Fernandez, Mehdi Gasmi, Dominick Vacante, Raymond T. Bartus, Kathie Bishop and Marie Printz
Mol Ther 9: S203-S204; doi:10.1016/j.ymthe.2004.06.667
540. Retroviral mediated gene transfer of Hexb in Sandhoff Disease
Susan S. Tom and Bruce A. Bunnell
Mol Ther 9: S204-S204; doi:10.1016/j.ymthe.2004.06.670
541. Mechanisms of adenovirus vector gene delivery to the inner ear
Douglas E. Brough, Mark Praetorius, Chi Hsu, Kim Baker and Hinrick Staecker
Mol Ther 9: S204-S204; doi:10.1016/j.ymthe.2004.06.671
542. DNA shuffling generates novel HIV-1 envelope variants that can induce broadly neutralizing antibodies in rabbits
Xiaohan Du, Li Xu, Wenge Zhang, Susan Tang, NayWei Soong, Michael B. Zwick, Dennis R. Burton and Robert G. Whalen
Mol Ther 9: S204-S204; doi:10.1016/j.ymthe.2004.06.457
543. Ad DNA polymerase and preterminal protein (pTP) genes each mediate inhibition of HIV-1 replication in human alveolar macrophages
Robert J. Kaner, Francisco Santiago, Dmitri Igonkin, Jerome Schaack, Andrea Amalfitano and Ronald G. Crystal
Mol Ther 9: S204-S205; doi:10.1016/j.ymthe.2004.06.458
544. Strong, Long-Lasting Immune Responses Against Lentivirus Antigens Using rSV40 Vectors Carrying HIV Tat and Envelope
Hayley J. McKee and David S. Strayer
Mol Ther 9: S205-S205; doi:10.1016/j.ymthe.2004.06.459
545. Lentiviral vector mediated gene transfer of the anti HIV gene revM10 into primitive hematopoietic cells for gene therapy of HIV infection
Ingrid Bahner, Gerald Cho, Barbara Engels, Denise Peterson, Karen Pepper and Donald B. Kohn
Mol Ther 9: S205-S206; doi:10.1016/j.ymthe.2004.06.499
546. Optimization of Expression of the SIV-Specific 9456 Ribozyme by the tRNAval PolIII Promoter within an MLV- or Lentiviral-Vector
S. E. Braun, FE Wong, AL Chesebro, B. Nornen, D. J. Looney, F. Wong-Staal and R. P. Johnson
Mol Ther 9: S206-S206; doi:10.1016/j.ymthe.2004.06.461
547. Antiviral RNA Interference Strategies That Resist HIV Escape
Joshua N. Leonard and David V. Schaffer
Mol Ther 9: S206-S206; doi:10.1016/j.ymthe.2004.06.463
548. Cyclophilin A as a cellular target for gene therapy of HIV-1
Harris S. Soifer, Reena Vishwanath, James Kim, Bret Heale, Lisa J. Scherer and John J. Rossi
Mol Ther 9: S206-S207; doi:10.1016/j.ymthe.2004.06.500
549. Nonconserved Sequence Motifs outside the Catalytic Core Improve the Trans-Splicing Efficiency of Anti-HIV Hammerhead Ribozymes
Marc Weinberg and John J. Rossi
Mol Ther 9: S207-S207; doi:10.1016/j.ymthe.2004.06.466
550. Use of Plant Polysaccharides as Topically Applied Adjuvants for Enhancing Immune Responses Via Transdermal Gene Vaccination
Jeng-Hwan Wang, Su-Jane Wang, Wen-Chi Wei, Chih-Chien Hsu, Chin-Jin Li and Ning-Sun Yang
Mol Ther 9: S207-S207; doi:10.1016/j.ymthe.2004.06.467
551. Enhanced Immune Stimulation and Antigen Presentation of i.m. Injected Plasmid DNA Vaccines by Electroporation
Baowei Peng, Yonggang Zhao and Yuhong Xu
Mol Ther 9: S207-S208; doi:10.1016/j.ymthe.2004.06.469
552. Single-Chain Antibodies for Viral-Based Passive Immuno-Therapy for Prion Disease: Linear Epitope Mapping and Clearance from Thalamic Injection
Charles A. Wuertzer, Mark A. Sullivan and Howard J. Federoff
Mol Ther 9: S208-S208; doi:10.1016/j.ymthe.2004.06.471
553. Silencing HBV Gene Expression with Pol II and Pol III Promoter-Derived Short Hairpin RNA
Sergio Carmona, Abdullah Ely, Naazneen Moolla, Marc Weinberg and Patrick Arbuthnot
Mol Ther 9: S208-S208; doi:10.1016/j.ymthe.2004.06.475
554. A Candidate SARS-Associated Coronavirus Vaccine Elicits Broad Immunity in Monkeys
Wentao Gao, Azaibi Tamin, Adam Soloff, Leonardo D'Aiuto, Edward Nwanegbo, Paul D. Robbins, William J. Bellini, Simon Barratt-Boyes and Andrea Gambotto
Mol Ther 9: S208-S208; doi:10.1016/j.ymthe.2004.06.480
555. Langerhans cells modified by gene transfer of full length CMV pp65 are more potent inducers of cytolytic T lymphocytes in a CD4-dependent manner than either CMV p495 gene-modified or p495 peptide-pulsed langerhans cells
Jianda Yuan, Jean-Baptiste Latouche, Joanna Hodges, Glenn Heller, Isabelle Riviere, Michel Sadelain and James W. Young
Mol Ther 9: S209-S209; doi:10.1016/j.ymthe.2004.06.482
556. Toward the Development of Electroporation for Delivery of DNA Vaccines to Humans
Dietmar Rabussay, Georg Widera, Lei Zhang, Gillis R. Otten, Barbara Doe, Mary Schaefer, Hong Liu and Jeffrey B. Ulmer
Mol Ther 9: S209-S209; doi:10.1016/j.ymthe.2004.06.483
557. Co-administration of an adenovirus encoding the B cell stimulating factor BAFF with heat-inactivated Pseudomonas aeruginosa leads to increased anti-pseudomonal humoral immunity
Christine Tertilt, Stefan Worgall, Michael C. Rivara and Ronald G. Crystal
Mol Ther 9: S210-S210; doi:10.1016/j.ymthe.2004.06.484
558. Anti-SARS Humoral and Cellular Immunity Evoked by an Adenovirus Vector Expressing Spike Glycoprotein from SARS Coronavirus
Julie Boyer, Anja Krause, Jianping Qiu, Neil Hackett, Gary Kobinger, Yan Zhi, James M. Wilson and Ronald G. Crystal
Mol Ther 9: S210-S210; doi:10.1016/j.ymthe.2004.06.485
559. Generating Powerful Immune Responses Against Lentiviral Antigens: Using rSV40 Vector-Delivered Proinflammatory Cytokines to Potentiate Immune Responses vs. rSV40-Delivered Lentiviral Antigens
Hayley J. McKee and David S. Strayer
Mol Ther 9: S211-S211; doi:10.1016/j.ymthe.2004.06.498
560. Induction of Prion Protein-Specific Antibody Responses Using PrP-Retroparticles
Daphne Nikles, Patricia Bach, Klaus Boller, Christoph A. Merten, Fabio Montrasio, Ulrich Kalinke, Klaus Cichutek and Christian J. Buchholz
Mol Ther 9: S211-S211; doi:10.1016/j.ymthe.2004.06.486
561. Recombinant Adenovirus Carrying Spike Gene Induces Effective Humoral and Cellular Immunity Against SARS-CoV in Rats
Ranyi Liu, Lizhe Wu, Bijun Huang, Jialin Huang and Wenlin Huang
Mol Ther 9: S211-S212; doi:10.1016/j.ymthe.2004.06.487
562. Human T-Cells Modified as Antigen Presenting Cells Are Superior to Professional APC in Stimulating T-Cell Responses
Eleni C. Adamopoulou, Christian Sinzger, Gabriele Kuntz, Christina Neff, Hermann Einsele, Hans G. Rammensee and Max S. Topp
Mol Ther 9: S212-S212; doi:10.1016/j.ymthe.2004.06.497
563. Determinants of a Humoral Immune Response Against the Transgene Product after Adenoviral Gene Transfer
Bart De Geest, Sophie Van Linthout, Jan Snoeys, Joke Lievens and D|[eacute]|sir|[eacute]| Collen
Mol Ther 9: S212-S212; doi:10.1016/j.ymthe.2004.06.496
564. T Cell Immunity Using Transgenic B Lymphocytes
Mara Gerloni, Marta Rizzi, Paola Castiglioni and Maurizio Zanetti
Mol Ther 9: S213-S213; doi:10.1016/j.ymthe.2004.06.488
565. Modulation of the Acute Phase Response by Recombinant Adeno-Associated Viral Expression of the IL-1 Type 1 Soluble Receptor
Gregory G. Simon, Barry J. Byrne and Mark A. Atkinson
Mol Ther 9: S213-S213; doi:10.1016/j.ymthe.2004.06.489
566. Inactivation of a Bacterial Quorum-Sensing Signal by Expression of Bacterial Autoinducer Inhibitor, aiiA, in Mammalian Cells
Egon A. Ozer and Joseph Zabner
Mol Ther 9: S213-S214; doi:10.1016/j.ymthe.2004.06.490
567. Effective Boosting of Protective Immunity Via Repeated Intramuscular Administration of a Human Adenovirus-Based Anthrax Vaccine
Yadi Tan, Julie L. Boyer, Neil R. Hackett and Ronald G. Crystal
Mol Ther 9: S214-S214; doi:10.1016/j.ymthe.2004.06.495
568. Comparison of Antigen-Specific Immune Responses Elicited by Recombinant Simian Adenoviral Vectors with Deletions in Either E1, or E1/E3, or E1/E4 Regions
Yan Zhi, Gary P. Kobinger, Heather Jordan, Guangping Gao and James M. Wilson
Mol Ther 9: S214-S214; doi:10.1016/j.ymthe.2004.06.491
569. Increased Antigen-Specific Humoral Response by Adenoviral Vector Prime and Adeno-Associated Viral Vector Boost
Yan Zhi, Lili Wang, Guangping Gao and James M. Wilson
Mol Ther 9: S214-S214; doi:10.1016/j.ymthe.2004.06.492
570. Genetic Vaccination Against Yersinia pestis Using Recombinant Adenovirus Vectors Expressing the V Antigen
Maria Chiuchiolo, Barry Shea, Julie L. Boyer, Neil R. Hackett and Ronald G. Crystal
Mol Ther 9: S215-S215; doi:10.1016/j.ymthe.2004.06.494
571. Expression of IL-27 in Murine Carcinoma Cells Produces T Cell-Dependent and -Independent Antitumor Effects
Masatoshi Tagawa, Masako Chiyo, Osamu Shimozato, Ling Yu and Takehiko Fujisawa
Mol Ther 9: S215-S215; doi:10.1016/j.ymthe.2004.06.501
572. Augmentation of Immuno-Gene Therapy for Lung Cancer Using Chemotherapy
Eiji Suzuki, Veena Kapoor, Arminder S. Jassar, Andrew Haas, Larry R. Kaiser and Steven M. Albelda
Mol Ther 9: S215-S216; doi:10.1016/j.ymthe.2004.06.502
573. Immuno Gene Therapy of Feline Fibrosarcoma Using Intratumoral Magnetofection for Gene Delivery |[ndash]| Preliminary Results of a Veterinary Clinical Study
Ulrike Schillinger, Niels Kjaergaard, Kathrin Wiedmann, Anne Loecher, Stefanie Schlemmer, Bianca Schwarz, Tina Kempf, Johannes Hirschberger, Roberto Koestlin, Christian Plank, Bernd Gansbacher and Thomas Brill
Mol Ther 9: S216-S216; doi:10.1016/j.ymthe.2004.06.503
574. Systemic IL-12 Eliminates Pre-Established Leukemia in a Murine Model of Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia
Tanja A. Gruber, Dianne C. Skelton, Karen Pepper, Denise Peterson and Donald B. Kohn
Mol Ther 9: S216-S217; doi:10.1016/j.ymthe.2004.06.504
575. Dendritic Cells Modified Using an Adenovirus Expressing Murine IL-12 Inhibits Development of Tumors in a Mouse Colon Cancer Model
Yoshio Sakai, Brian J. Morrison, John E. Janik and John C. Morris
Mol Ther 9: S217-S217; doi:10.1016/j.ymthe.2004.06.505
576. Antitumoral Effect Mediated by Two SFV-IL-12 Expression Vectors in a Murine Model of Colon Adenocarcinoma
Juan R. Rodriguez-Madoz, Erkuden Casales, Min Guan, Jesus Prieto and Cristian Smerdou
Mol Ther 9: S217-S218; doi:10.1016/j.ymthe.2004.06.506
577. MVA-MUC1-IL2 Vaccine Immunotherapy for Patients Post-Prostatectomy with Rising PSA and No Evident Metastases
Robert Dreicer, Frederick Ahman, Allan Pantuck, Caroline Beunkens, Nadine Bizouarne, Bruce Acres, Teresa Maciejewska and Patrick Squiban
Mol Ther 9: S218-S218; doi:10.1016/j.ymthe.2004.06.507
578. Enhancement of GM-CSF secreting tumor cell vaccines by docetaxel through immune-dependent and independent mechanisms
Rodney A. Prell, Lisa Sampson, Melinda VanRoey and Karin U. Jooss
Mol Ther 9: S218-S218; doi:10.1016/j.ymthe.2004.06.508
579. Generation of potent cellular immune responses induced by intradermal delivery of plasmid DNA coexpressing Flt3 ligand and GM-CSF
Yi-Te Yo, Chao-Liang Wu, Chi-Wen Lo and Ai-Li Shiau
Mol Ther 9: S219-S219; doi:10.1016/j.ymthe.2004.06.509
580. Inducible expression of interleukin-12 for the treatment of liver metastases using a high-capacity adenoviral vector
Ruben Hernandez-Alcoceba, Itsaso Mauleon, Maider Zabala, Vijay Shankar, Stefan Kochanek, Jesus Prieto and Cheng Qian
Mol Ther 9: S219-S219; doi:10.1016/j.ymthe.2004.06.510
581. Enhanced antitumor effect of interleukin-12 and B7.1 expressing oncolytic adenovirus in immunocompetent mouse
Young-Sook Lee, Kyung-Ju Cho, Sungae Cho, Chae-Ok Yun and Joo-Hang Kim
Mol Ther 9: S219-S220; doi:10.1016/j.ymthe.2004.06.511
582. Detection of enhanced serum antibody production to renal cell cancer proteins and identification of serological tumor antigens in patients treated with the GM-CSF-gene transduced-autologous tumor vaccines (GVAX|[reg]|)
Takao Hashiguchi, Yukoh Nakazaki, Shirley Clift, Dale G. Ando, Shigetaka Asano and Kenzaburo Tani
Mol Ther 9: S220-S220; doi:10.1016/j.ymthe.2004.06.512
583. Efficient Non-Viral Gene Delivery to Primary, Leukemia B Cells by mRNA Transfection
Linhong Li, Cornell Allen, Rama Shivakumar, Jonathan M. Weiss, Joseph C. Fratantoni and Linda N. Liu
Mol Ther 9: S220-S220; doi:10.1016/j.ymthe.2004.06.513
584. Intratumoral Electrotransfer of Interleukin-12 Gene and Bleomycin Synergistically Induced Therapeutic Immunity and Suppressed Subcutaneous and Metastatic Melanomas in Mice
Tsunao Kishida, Hidetsugu Asada, Hiroshi Nakano, Kakei S. Yasutomi, Masaharu Shin-ya, Takashi Shinomiya, Feng-De Cui, Yasuo Hisa, Jiro Imanishi and Osam Mazda
Mol Ther 9: S221-S221; doi:10.1016/j.ymthe.2004.06.514
585. Anti-Angiogenic Drugs Synergize with a Membrane Macrophage Colony Stimulating Factor (mM-CSF) Based Tumor Vaccine to Therapeutically Treat Rats with an Established Intracranial Glioma
Martin R. Jadus, Edward W. B. Jeffes, Ramon Sanchez, Christina Delgado, Jian G. Zhang, Sakineh Khalaghizadeh, Tetyana Khomenko, Animesh Petkar, Chirag Shah, Brandon Knight, Seema Vohra, Reza Jahroudi and Terry Wepsic
Mol Ther 9: S221-S221; doi:10.1016/j.ymthe.2004.06.515
586. Gene transfer of IP10, IP10+CD154 or IP10+IL12 cDNA induces an anti-leukemic immunity in a murine model of acute leukemia
Aurore Saudemont and Bruno Quesnel
Mol Ther 9: S221-S222; doi:10.1016/j.ymthe.2004.06.531
587. Further advances in immuno-gene therapy against human papillomavirus by adeno-associated virus gene transfer into dendritic cells
Yong Liu, Maurizio Chiriva-Internati, Hong You, Jawahar L. Mehta and Paul L. Hermonat
Mol Ther 9: S222-S222; doi:10.1016/j.ymthe.2004.06.557
588. A central role of RNA in developing therapeutic vaccines for cancer and infectious diseases
Eli Gilboa, Sandra Santulli-Marotto, Smita K. Nair, David Boczkowski and Yanbing Zhao
Mol Ther 9: S222-S222; doi:10.1016/j.ymthe.2004.06.558
589. Therapeutic efficacy and cellular mechanism mediated by intratumoral and intramuscular IL-12 electrogenetherapy
Shulin Li, Francesca Mellieon and Robin Barret
Mol Ther 9: S222-S222; doi:10.1016/j.ymthe.2004.06.559
590. SuperCD enables low dose 5-FC application for effective suicide gene therapy in a rat hepatoma model both in vitro and in vivo
Marie-Luise Lemken, Florian Graepler, Wolfgang A. Wybranietz, Ulrike Schmidt, Irina Smirnow, Christine D. Gross, Martin Spiegel, Andrea Schenk, Hansjoerg Graf, Ulrike A. Lauer, Michael Gregor, Sorin Armeanu, Michael Bitzer and Ulrich M. Lauer
Mol Ther 9: S223-S223; doi:10.1016/j.ymthe.2004.06.517
591. Comparison of plant-TK/AZT versus HSV-TK/ganciclovir enzyme/prodrug systems in a human glioma cell line
Mette Willer, Peter Kristoffersen and Zoran Gojkovic
Mol Ther 9: S223-S223; doi:10.1016/j.ymthe.2004.06.516
592. Transfection of human oral cancer cells mediated by transferrin-associated lipoplexes: mechanisms of cell death induced by herpes simplex virus thimidine kinase/ganciclovir therapy
Silvia S. Neves, Sergio M. Simoes and Maria C. Pedroso de Lima
Mol Ther 9: S223-S224; doi:10.1016/j.ymthe.2004.06.518
593. Recombinant measles viruses encoding suicide genes for oncolytic therapy
Christoph Springfeld, von Messling Veronika, Frenzke Marie and Cattaneo Roberto
Mol Ther 9: S224-S224; doi:10.1016/j.ymthe.2004.06.519
594. Gene-directed enzyme therapy with carboxylesterase/CPT-11, but not thymidine kinase/GCV, enhances the efficacy of the conditionally replicating adenovirus Ad|[Delta]|24
Dinja Oosterhoff, Herbert M. Pinedo, M. Adhiambo Witlox, Jan E. Carette, Winald R. Gerritsen and Victor W. van Beusechem
Mol Ther 9: S224-S225; doi:10.1016/j.ymthe.2004.06.520
595. Combination tissue specific SCC antigen promoter with cd/5-fc gene therapy enhances killing of human uterine cervical cancer cells by radiation
Keng-Fu Hsu, Cheng-Yang Chou, Helen H. W. Chen, Che-Hsin Lee, Ai-Li Shiau and Chao-Liang Wu
Mol Ther 9: S225-S225; doi:10.1016/j.ymthe.2004.06.521
596. Radiosensitization of gliomas using lentiviral vectors expressing antisense ATM
Teong L. Chuah, David G. Walker, Ming Q. Wei, Shaun P. Scott and Martin F. Lavin
Mol Ther 9: S225-S225; doi:10.1016/j.ymthe.2004.06.522
597. Combined suicide/cytokine gene therapy of hepatocellular carcinoma
Anna-Lisa Stefani, Luisa Barzon, Ignazio Castagliuolo, Maria Guido, Fabio Farinati and Giorgio Pal|[ugrave]|
Mol Ther 9: S226-S226; doi:10.1016/j.ymthe.2004.06.554
598. Interleukin-2 enhanced the anti-tumor effect of adenoviral-mediated HSV-tk gene therapy in a murine bladder cancer model
Shiji Terao, Toshiro Sirakawa, Nobuyuki Hinata, Sadao Kamidono and Akinobu Gotoh
Mol Ther 9: S226-S226; doi:10.1016/j.ymthe.2004.06.523
599. Low-dose etoposide enhances tumor-specific adenovirus-mediated cytosine deaminase gene therapy through induction of integrin |[alpha]|v|[beta]|3 and |[alpha]|v|[beta]|5 overexpression and upregulation of human telomerase reverse transcriptase promoter
Gia-Shing Shieh, Tzong-Shin Tzai, Yi-Te Yo, Ai-Li Shiau and Chao-Liang Wu
Mol Ther 9: S226-S227; doi:10.1016/j.ymthe.2004.06.555
600. Fusion of HSV-1 thymidine kinase to an 11 aa-peptide from the HIV-1 tat protein promotes intercellular trafficking and enhances anti-tumoral activity in vivo
Ennio Tasciotti and Mauro Giacca
Mol Ther 9: S227-S227; doi:10.1016/j.ymthe.2004.06.524
601. HIV-1 TAT protein transduction domain-mediated enhancement of HSV-TK/ganciclovir suicide gene therapy
Outi Meril|[auml]|inen, Tanja Hakkarainen, Tiina Pasanen, Riikka Pellinen and Jarmo Wahlfors
Mol Ther 9: S227-S228; doi:10.1016/j.ymthe.2004.06.525
602. Utilization of VP22 in cancer gene therapy
Tanja Hakkarainen, Tiina Pasanen and Jarmo Wahlfors
Mol Ther 9: S228-S228; doi:10.1016/j.ymthe.2004.06.526
603. Prostate tumor regression following adenoviral delivery of Flp recombinase-regulated diphtheria toxin expression
Janet A. Sawicki and Weidan Peng
Mol Ther 9: S228-S228; doi:10.1016/j.ymthe.2004.06.556
604. Phase I/II clinical trial of Ad-OC-TK plus VAL for the patients with metastatic or local recurrent prostate cancer: initial experience in Japan
Toshiro Shirakawa, Nobuyuki Hinata, Shuji Terao, Katsumi Shigemura, Naonori Taniguch, Kazuhito Fukushima, Khoji Sugimoto, Kazuro Sugimura, Masafumi Matsuo, Sakan Maeda, Sadao Kamidono, Chinghai Kao, Thomas A. Gardner, Leland W. K. Chung and Akinobu Gotoh
Mol Ther 9: S228-S229; doi:10.1016/j.ymthe.2004.06.527
605. Cytokine profile assessment of mesothelioma patients treated with escalating doses of intrapleurally administered, genetically modified PA1STK cells and a twice daily regiment of ganciclovir. a Phase I clinical trial
Patrick S. Byrne, Paul O. Schwarzenberger, Lynn Harrison, Judy Norton and Jay K. Kolls
Mol Ther 9: S229-S229; doi:10.1016/j.ymthe.2004.06.528
606. The NOD-SCID |[beta]|2M null mouse xenograft model for studying activation, expansion and GvHD potential of gene transduced human t cells in vivo
Jon E. Walker, Gerhard Bauer, Phillip Herrbrich, David Hess, Todd Meyerrose, Bruno Nervi, Michael Rettig, Jan A. Nolta and John F. DiPersio
Mol Ther 9: S229-S229; doi:10.1016/j.ymthe.2004.06.1010
607. In vitro and in vivo monitoring of 5-fluorosytosine metabolism with 19F-NMR spectroscopy after adenoviral transduction of cells with bifunctional yeast CDUPRT fusion gene
Vera Simonenko, Huandong Pageant, Du Fei and Thian C. Ng
Mol Ther 9: S230-S230; doi:10.1016/j.ymthe.2004.06.530
608. VAI deleted adenovirus as an oncolytic agent targeting human EBV-associated tumours
Yaohe Wang, Shao-an Xue, Gunnel Hallden, Jennelle Francis, Beverly E. Griffin and Nick R. Lemoine
Mol Ther 9: S230-S230; doi:10.1016/j.ymthe.2004.06.532
609. Highly active, cancer specific promoters for gene therapy of small cell lung cancer
Nina Pedersen, Mikkel W. Pedersen, Thomas T. Poulsen and Hans S. Poulsen
Mol Ther 9: S230-S231; doi:10.1016/j.ymthe.2004.06.533
610. Elucidating the mechanism(s) for tumor specificity of attenuated measles virus
Bambi D. Anderson, Takafumi Nakamura, Stephen J. Russell and Kah-Whye Peng
Mol Ther 9: S231-S231; doi:10.1016/j.ymthe.2004.06.534
611. Group I intron-mediated trans-splicing revision of mutant p53 RNA transcripts
Daniel J. Catron, Takashi Watanabe, Kyung-Sook Shin, Eric M. Toloza, Seong-Wook Lee and Bruce A. Sullenger
Mol Ther 9: S231-S231; doi:10.1016/j.ymthe.2004.06.535
612. Effect of adenovirus dl520 as replicating agent in combination with fractionated radiotherapy in a glioma xenograft model
Alexa Bieler, Alexandra Bernshausen, Sybille Staerk, Anka Grosso, Bernd Gaensbacher and Per Sonne Holm
Mol Ther 9: S232-S232; doi:10.1016/j.ymthe.2004.06.536
613. Display of different protein scaffolds on envelope glycoprotein of avian leukosis virus
Pranay D. Khare, Stephen J. Russell and Mark J. Federspiel
Mol Ther 9: S232-S232; doi:10.1016/j.ymthe.2004.06.537
614. In vivo and in vitro characterisation of library selected matrix metalloprotease activatable retroviruses
Irene Hartl, Richard M. Schneider, Yuansheng Sun, Stephen J. Russell, Christian J. Buchholz and Klaus Cichutek
Mol Ther 9: S232-S233; doi:10.1016/j.ymthe.2004.06.538
615. Feasibility of hTERT-targeting trans-splicing ribozyme in tumor-targeted gene therapy
Seung-Hee Hong, Yoon-Jong Lee, Haeng-Im Jung, Byung-Su Kwon, Seong-Wook Lee, Jin-Sook Jeong, Chang-Min Kim and In-Hoo Kim
Mol Ther 9: S233-S233; doi:10.1016/j.ymthe.2004.06.539
616. Retargeted Selectively Replicating Adenoviruses for the Therapy of Colon Cancer
Krisztian Gy Homicsko, Christophe Fuerer and Richard Iggo
Mol Ther 9: S233-S233; doi:10.1016/j.ymthe.2004.06.540
617. Prostate Cancer Radiosensitization by Targeting Poly(ADP-ribose) Polymerase
Li Zhang, Prafulla Gokhale, Rajshree Mewani, Bihua Li, Anatoly Dritschilo and Viatcheslav Soldatenkov
Mol Ther 9: S234-S234; doi:10.1016/j.ymthe.2004.06.541
618. Coxsackie-Adenovirus Receptor (CAR) Levels Can Be Increased in Human Xenografts Followed by Treatment with FK228, a Histone Deacetylase Inhibitor
Alian Aguila, Merrill E. Goldsmith, Santhi J. Gollapalli, Michael C. Alley, William W. Waud, Susan Bates and Tito Fojo
Mol Ther 9: S234-S234; doi:10.1016/j.ymthe.2004.06.542
619. Augmentation of Anti-Tumor Activity of a Recombinant Adeno-Associated Virus 2 Carcinoembryonic Antigen Vaccine with Plasmid Adjuvants
Selvarangan Ponnazhagan, Gandham Mahendra, Jose Lima, Wayne Aldrich, Connie Jenkins, Changchun Ren, Sanjay Kumar, Lisa Kallman, Theresa V. Strong, Denise R. Shaw and Pierre L. Triozzi
Mol Ther 9: S234-S235; doi:10.1016/j.ymthe.2004.06.543
620. A Longer Human Telomerase Reverse Transcriptase Promoter-Based Conditionally Replicative Adenovirus Shows Oncolysis with Less Toxicity for Ovarian Cancer Treatment
Yosuke Kawakami, Koichi Takayama, Masato Yamamoto, Dirk M. Nettelbeck, Minghui Wang, Mack N. Barnes, Gene P. Siegal, Ronald D. Alvarez, David T. Curiel and Jerry L. Blackwell
Mol Ther 9: S235-S235; doi:10.1016/j.ymthe.2004.06.544
621. Translational Restriction of Protein Expression of a Modifed Suicide Gene and Cytotoxicity in Human Mammary Tumor Cells Expressing High Levels of the Translation Initiation Factor eIF4E
Don A. Sibley, James M. Mathis, Yoshi Odaka, B. J. Williams and Arrico DeBenedetti
Mol Ther 9: S235-S235; doi:10.1016/j.ymthe.2004.06.545
622. Discovery of Targeting Peptides for Selective Therapy of Medullary Thyroid Carcinoma
Miriam B|[ouml]|ckmann, Matthias Drosten and Brigitte M. P|[uuml]|tzer
Mol Ther 9: S236-S236; doi:10.1016/j.ymthe.2004.06.546
623. Transcriptional Targeting of Breast Cancer Employing the Heparanase Promoter
Martina Breidenbach, Daniel T. Rein, Yuko Tsuruta, Minghui Wang, Isabell Herrmann, Ronald D. Alvarez, Paul N. Reynolds and David T. Curiel
Mol Ther 9: S236-S236; doi:10.1016/j.ymthe.2004.06.547
624. Effect of an Oncolytic HSV Mutant Expressing ICP34.5 under Control of a Nestin Promoter for Brain Tumor Therapy
Hirokazu Kambara, Hideyuki Okano, E. Antonio Chiocca and Yoshinaga Saeki
Mol Ther 9: S236-S237; doi:10.1016/j.ymthe.2004.06.548
625. AAV Gene Therapy for Liver Metastatic Cancer
Ray A. Xu, Kevin Sun, Geoffrey W. Krissansen, Peter W. Fung, Sue Xu, Weidong Xiao, Juan Shi and Sheung-tat Fan
Mol Ther 9: S237-S237; doi:10.1016/j.ymthe.2004.06.549
626. A Novel Prostate-Specific Adenovirus for Gene Expression in Hormone-Sensitive and Hormone-Refractory Prostate Cancer Cells
Wing-Shing Cheng and Magnus Essand
Mol Ther 9: S237-S237; doi:10.1016/j.ymthe.2004.06.550
627. Widespread Intratumoral Viral Distribution Enables Local Control of Large Human Sarcoma Xenografts by Oncolytic Herpes Simplex Viruses
Mark A. Currier, Yoni H. Mahller, Lisa C. Adams, Brian Horsburgh, Frank Tufaro and Timothy P. Cripe
Mol Ther 9: S237-S237; doi:10.1016/j.ymthe.2004.06.551
628. An Oncolytic Adenovirus Armed with a GM-CSF Activating Designed Zinc-Finger Protein Transcription Factor: A Potential Cancer Vaccine Approach
Andreas Reik, Philip D. Gregory and Casey C. Case
Mol Ther 9: S238-S238; doi:10.1016/j.ymthe.2004.06.552
629. VEGF Promoter-Based Conditionally Replicative Adenoviruses Are Useful for the Treatment of Malignant Pleural Mesothelioma
Koichi Takayama, Akiko Ikegami, Hiroyuki Inoue, Lioudmila Kaliberova, Junji Uchino, David T. Curiel and Yoichi Nakanishi
Mol Ther 9: S238-S238; doi:10.1016/j.ymthe.2004.06.553
630. Tamoxifen-Inducible Expansion of Murine Hematopoietic Stem Cells by Retroviral-Mediated Transfer of a HOXB4-ERT2 Fusion Protein
Yan Shou, Lilia Stepanova and Brian P. Sorrentino
Mol Ther 9: S238-S239; doi:10.1016/j.ymthe.2004.06.560
631. Modulation of Immune Response to Gene Therapy Derived Products by CD4+ CD25+ T Regulatory Cells
Andrea Annoni, Manuela Battaglia, Antonia Follenzi, Angelo Lombardo, Luigi Naldini and Maria-Grazia Roncarolo
Mol Ther 9: S239-S239; doi:10.1016/j.ymthe.2004.06.561
632. Retrovirally Transduced Muscle-Derived Stem Cells Facilitate Repair of Osteochondral Defects
Ryosuke Kuroda, Arvydas Usas, Hairong Peng, Masamitsu Sakamoto and Johnny Huard
Mol Ther 9: S239-S239; doi:10.1016/j.ymthe.2004.06.563
633. Dose-Dependent Gene Silencing by Lentivirus-Mediated RNA Interference (RNAi) in bcr-abl Positive Cells
Michaela Scherr, Karin Battmer, Arnold Ganser and Matthias Eder
Mol Ther 9: S240-S240; doi:10.1016/j.ymthe.2004.06.565
634. The Role of Ink4a-Arf Locus in Control of Hematopoietic Stem Cell Proliferation
Lilia Stepanova and Brian P. Sorrentino
Mol Ther 9: S240-S240; doi:10.1016/j.ymthe.2004.06.567
635. Macrophage Colony Stimulating Factor Expression in Retrovirally Transfected Cells Is Dependent upon the Adherence Status of the Target Cells
JianGang Zhang, Qinghong Dan, Timothy C. Fong, Christopher C. Williams, Maria D. Avina, Mehrdokht Tarbiyat-Boldaji, Sakineh Khalaghizadeh, Michael Irwin, Amy Nyugen, H. Terry Wepsic and Martin R. Jadus
Mol Ther 9: S240-S241; doi:10.1016/j.ymthe.2004.06.569
636. Reversal of Hypothalamic Diabetes Insipidus Using EIAV-Based Regulatable Lentiviral Vectors Expressing Arginine Vasopressin
Alison Bienemann, Pippa Radcliffe, Kyri Mitrophanous, Colin Glover, Nicholas Mazarakis and James Uney
Mol Ther 9: S241-S241; doi:10.1016/j.ymthe.2004.06.571
637. Intrathecal Electroporation of Doxycycline Regulated Proopiomelanocortin Gene for the Neuropathic Pain Therapy in CCI Rats
Chung-Ren Lin, Chien-Ming Wu, Ming-Wei Lin and Jiin-Tsuey Cheng
Mol Ther 9: S241-S241; doi:10.1016/j.ymthe.2004.06.573
638. Therapeutic Antisense-Induced Exon Skipping for Duchenne Muscular Dystrophy
Annemieke Aartsma-Rus, Anneke A. M. Janson, Wendy E. Kaman, Mattie Bremmer-Bout, Christa L. de Winter, Habte F. Teshale, Gert-Jan B. van Ommen, Johan T. den Dunnen and Judith C. T. van Deutekom
Mol Ther 9: S241-S242; doi:10.1016/j.ymthe.2004.06.575
639. Gene Expression Analysis of LPS Stimulated THP-1 Cells Treated with Antisense IRAK1 Delivered Using a pH-Sensitive, Membrane Disruptive Polymer
Rachel E. Johns, Allan S. Hoffman and Patrick S. Stayton
Mol Ther 9: S242-S242; doi:10.1016/j.ymthe.2004.06.577
640. E1Bp-Specific CD8+ T Lymphocytes Are Highly Induced in the Liver and Spleen Eight Days after Adenoviral Infection
Jian Chen, Sylvia A. McPherson, Allan Zajac, Hui-Chen Hsu, Qi Wu, Pingar Yang, Xin Xu, David T. Curiel and John D. Mountz
Mol Ther 9: S242-S242; doi:10.1016/j.ymthe.2004.06.578
641. Tetracycline-Inducible Human GDNF Expression Mediated by a Single AAV Vector
Abdelwahed Chtarto, Catherine Melas, David Blum, Jean-Marie Jaspar, Thierry Velu, Jacques Brotchi, Marc Levivier and Liliane Tenenbaum
Mol Ther 9: S243-S243; doi:10.1016/j.ymthe.2004.06.579
642. In Vitro Rescue of Radiosensitive Phenotype Using a Novel Human Artificial Chromosome (HAC) Vector Containing DNA-PKcs Gene
Akihiro Otsuki, Akihiro Kurimasa, Candice G. T. Tahimic, Motonobu Katoh and Mitsuo Oshimura
Mol Ther 9: S243-S243; doi:10.1016/j.ymthe.2004.06.580
643. Prolonged Expression of Human Alpha-1-Antitrypsin in C3H/Hej Mice with Helper-Dependent Adenoviral Vectors Irrespective of Tissue Distribution of Gene Expression
W. Michael McCormack, Racel G. Cela, Christian Clarke, Viraj Mane, Kiran Ubhayakar and Brendan H. Lee
Mol Ther 9: S243-S243; doi:10.1016/j.ymthe.2004.06.581
644. Decreased Generation and Cytotoxic Function of Adenovirus-Specific CD8 T Cells in Both CD28 and FasL Deficient Mice
Jian Chen, Sylvia A. McPherson, Allan Zajac, Hui-Chen Hsu, Qi Wu, Pingar Yang, David T. Curiel and John D. Mountz
Mol Ther 9: S244-S244; doi:10.1016/j.ymthe.2004.06.585
645. AAV Mediated Human Insulin Gene Expression in Liver of Diabetic Rats
Seonock Woo and Hyejoo Kim
Mol Ther 9: S244-S244; doi:10.1016/j.ymthe.2004.06.586
646. Covalently-Closed, Dumbbell-Shaped Double-Stem-Loop DNA Constructs (dSLIM) with Specific Immunomodulatory Function
Nicole Hagner, Astrid Sander, Juliana K|[ouml]|ck, Sven A. K|[ouml]|nig-Merediz, Burghardt Wittig and Manuel Schmidt
Mol Ther 9: S244-S245; doi:10.1016/j.ymthe.2004.06.588
647. AP20817-Inducible Activation of a Chimeric Insulin Receptor Mimics Insulin Action in Hepatocytes Transduced with AAV
Alberto Auricchio, Gabriella Cotugno, Pietro Formisano, Francesco Beguinot, Enrico M. Surace and Roy Pollock
Mol Ther 9: S245-S245; doi:10.1016/j.ymthe.2004.06.590
648. In-Vivo Adenovirus Mediated RNA Interference of Multidrug Resistance Protein-2 (MRP-2/ABCC2/cMOAT)
I|[ntilde]|igo Narvaiza, Mar|[iacute]|a Vera, Nerea Razquin, Mikel Zaratiegui, Jes|[uacute]|s Prieto and Puri Fortes
Mol Ther 9: S245-S245; doi:10.1016/j.ymthe.2004.06.592
649. Repression of Vascular Endothelial Growth Factor-A Over-Expression in Glioblastoma Cells Using Engineered Zinc-Finger Transcription Factors
Andrew W. Snowden, Lei Zhang, Fyodor Urnov, Carolyn Dent, Andrew R. McNamara, Yann Jouvenot, Steve H. Zhang, Edward J. Rebar, Andrew C. Jamieson, Casey C. Case and Philip D. Gregory
Mol Ther 9: S245-S245; doi:10.1016/j.ymthe.2004.06.593
650. Hypoxia-Inducible Factor-1a DNA Induced Angiogenesis in Cerebral Ischemia Model in the Rat
Tatsuya Abe, Tsuyoshi Matsuda, Jian Liang Wu, Ryo Inoue, Minoru Fujiki and Hidenori Kobayashi
Mol Ther 9: S246-S246; doi:10.1016/j.ymthe.2004.06.595
651. The CD34 Antigen Molecular Domains Implied in Potential Homing and Engraftment of Hematopoietic Progenitors
Gurudutta U. Gangenahalli, Vimal K. Singh, Soumya Pati, Yogesh K. Verma, Pallavi Gupta, Rajat Kumar, Rakesh K. Sharma and Pratibha M. Luthra
Mol Ther 9: S246-S246; doi:10.1016/j.ymthe.2004.06.596
652. Analysis of the Genomic Stability of Herpes Simplex Virus Thymidine Kinase Variants in Retrovirally Transduced Lymphocytes
Vanessa L. Capacio, Yong Fan, Jolanta Stefanski, Alex H. Chang, Michel Sadelain and Isabelle Rivi|[egrave]|re
Mol Ther 9: S246-S247; doi:10.1016/j.ymthe.2004.06.597
653. Activation of an ATM/chk2-Dependent Pathway Is Required for HSV-1 Protein ICp0 Induced G2/M Cell Cycle Arrest
Han Li and Joseph C. Glorioso
Mol Ther 9: S247-S247; doi:10.1016/j.ymthe.2004.06.599
654. rAAV Mediated Ribozyme Delivery Targeting Mouse Rhodopsin
Marina Gorbatyuk, J. J. Pang, William W. Hauswirth and Alfred S. Lewin
Mol Ther 9: S247-S247; doi:10.1016/j.ymthe.2004.06.600
655. Gene Therapy for Inhibition of Corneal Neovascularization in a Mice Model with Endostatin Delivered by Adeno-Associated Viral (AAV) Vector
Li-Ju Lai, Jane Li, Ken-Kuo Lin, Zhoung Wang, Tong Zhu and Xiao Xiao
Mol Ther 9: S247-S248; doi:10.1016/j.ymthe.2004.06.601
656. Potential Regulatory Function of Dendritic Cells Overexpression Indoleamine 2,3-Dioxygenase
Naoko Funeshima, Masayuki Fujino, Yusuke Kitazawa, Torayuki Okuyama and Xiao-kang Li
Mol Ther 9: S248-S248; doi:10.1016/j.ymthe.2004.06.602
657. Immune Responses to Transgene Expression Targeted to Keratinocytes
Soosan Ghazizadeh, Lorne B. Taichman and Richard S. Kalish
Mol Ther 9: S248-S248; doi:10.1016/j.ymthe.2004.06.603
658. Different Regulation of Atrial and Ventricular HSP70 mRNA Expression during Warm Blood Cardioplegic Arrest in Rats
Ern|[ouml]| Remsey-Semmelweis, John G. Kral, Richard B. Wait and M. A. Q. Siddiqui
Mol Ther 9: S248-S248; doi:10.1016/j.ymthe.2004.06.604
659. Development of Designed Zinc Finger Protein Transcriptional Regulators for Use in Multi-Factor Therapeutic Angiogenesis
Edward J. Rebar, Brian Johnstone, Pei-Qi Liu, Andrew C. Jamieson, Yuxin Liang, Lei Zhang, Matthew C. Mendel, Lei Xu, Kaye Spratt and Casey C. Case
Mol Ther 9: S248-S249; doi:10.1016/j.ymthe.2004.06.605
660. Efficient Production of Transgenic Pigs by Lentiviral Gene Transfer into Preimplantation Embryos
Andreas Hofmann, Barbara Kessler, Sonja Ewerling, Marc Boelhauve, Gottfried Brem, Eckhard Wolf and Alexander Pfeifer
Mol Ther 9: S249-S249; doi:10.1016/j.ymthe.2004.06.606
661. Immune System Regulation of Transgene Expression in the Brain 3: Effects of the Immune Response on Transgene Expression from HIV-Derived Lentiviral Vectors Injected into the Rat Striatum
Pedro R. Lowenstein, Evelyn Abordo-Adesida, Carlos Barcia, Antonio Follenzi, Luigi Naldini and Maria G. Castro
Mol Ther 9: S249-S250; doi:10.1016/j.ymthe.2004.06.607
662. Adenovirus Targeting Via Leucine Zipper Peptide Ligand Attachment
Joel N. Glasgow, Abner Mhashilkar, David T. Curiel and Nikolay Korokhov
Mol Ther 9: S250-S250; doi:10.1016/j.ymthe.2004.06.626
663. Genetic Re-Targeting of Adenovirus Using a Hyperstable scFv Domain and an Affibody|[reg]| Molecule Against Her2/neu
Leif Lindholm, Karin Andersson, Pierre Boulanger, Karolin Frykholm, Petra Henning, Rob Hoeben, Saw See Hong, Jenny Johannisson, Maria Magnusson, Susanna Myhre, Per-|[Aring]|ke Nygren, Elisabeth Pettersson, Stefan St|[aring]|hl, Jort Vellinga and Maria Wikman
Mol Ther 9: S250-S250; doi:10.1016/j.ymthe.2004.06.627
664. Surface-Expressed Angiotensin-Converting Enzyme as a Novel Approach To Target Adenovirus to Dendritic Cells
Yosuke Kawakami, Sergei M. Danilov, Paul N. Reynolds, Jessica M. Grunda, Michael Passineau, Irina V. Balyasnikova, Joel N. Glasgow, Minghui Wang, Zen-Bian Zhu, Pierre L. Triozzi, Wayne A. Aldrich, Jerry L. Blackwell and David T. Curiel
Mol Ther 9: S251-S251; doi:10.1016/j.ymthe.2004.06.628
665. Enhanced Transgene Delivery to Activated Vascular Endothelial Cells In Vitro and In Vivo Using a Novel Strategy To Modify Adenovirus Tropism
Kenichi Ogawara, Marianne G. Rots, Robbert J. Kok, Dirk K. F. Meijer, Grietje Molema and Hidde J. Haisma
Mol Ther 9: S251-S251; doi:10.1016/j.ymthe.2004.06.629
666. Effect of Adenovirus Serotype 5 Fiber and Penton Modifications on In Vivo Tropism in Rats
Campbell G. Nicol, Delyth Graham, William H. Miller, Theodore A. G. Smith, Stuart A. Nicklin, Susan C. Stevenson and Andrew H. Baker
Mol Ther 9: S251-S252; doi:10.1016/j.ymthe.2004.06.630
667. A Novel Platform for Chemical Modification of Adenovirus Vector Capsids Based on Reactive Cysteines
Florian Kreppel, Judith Gackowski, Erika Schmidt and Stefan Kochanek
Mol Ther 9: S252-S252; doi:10.1016/j.ymthe.2004.06.631
668. Affinity Immobilization of Adenoviral Vector on the Surface of Nanoparticles Augments Transduction
Ilia Fishbein, Michael Chorny, Ivan S. Alferiev, Origene Nyanguile and Robert J. Levy
Mol Ther 9: S252-S253; doi:10.1016/j.ymthe.2004.06.632
669. Light-Induced Adenovirus Gene Transfer
Birgit Engesaeter, Anette Bonsted, Anders Hoegset, Kristian Berg and Gunhild Maelandsmoe
Mol Ther 9: S253-S253; doi:10.1016/j.ymthe.2004.06.633
670. Intracellular Shigatoxin 1A1 Delivered by Adenovirus-Mediated Segmental Trans-Splicing Causes Apototic Cell Death In Vitro and In Vivo
Katsutoshi Nakayama, Robert G. Pergolizzi and Ronald G. Crystal
Mol Ther 9: S253-S253; doi:10.1016/j.ymthe.2004.06.634
671. Overexpression of Manganese Superoxide Dismutase (MnSOD) Prevents Photodynamic Therapy (PDT)-Induced Porcine Esophageal Stricture
Anurag Agarwal, Michael W. Epperly, Yaron Perry, James D. Luketich and Joel S. Greenberger
Mol Ther 9: S254-S254; doi:10.1016/j.ymthe.2004.06.635
672. Lentiviral Transduction of INK4A/ARF Protein Cooperates with Anti-Leukemic Agents To Induce Apoptosis of Leukemia Cells
Yuansong Bai, Yasushi Soda, Minghan Chen, Kiyoko Izawa, Seiichiro Kobayashi, Akira Tomonari, Jun Ooi, Fumitaka Nagamura, Satoshi Takahashi, Kaoru Uchimaru, Tohru Iseki, Hiroyuki Miyoshi, Tsuneo A. Takahashi, Kenzaburo Tani, Arinobu Tojo and Shigetaka Asano
Mol Ther 9: S254-S254; doi:10.1016/j.ymthe.2004.06.636
673. Injection of Progenitor Cells from the Bone Marrow or Esophagus Prevents Irradiation-Induced Esophagitis
YunYun Niu, Michael W. Epperly, Hongmei Shen and Joel S. Greenberger
Mol Ther 9: S255-S255; doi:10.1016/j.ymthe.2004.06.637
674. Improved Therapy of Prostate Carcinoma with TRAIL Gene Delivery Using Flt-1 Promoter Element in Combination with Ionizing Radiation
Sergey A. Kaliberov, Lyudmila N. Kaliberova and Donald J. Buchsbaum
Mol Ther 9: S255-S255; doi:10.1016/j.ymthe.2004.06.638
675. Combination Therapy of Ad-mda7 and Herceptin Increases Cell Death in Her-2/Neu Positive Breast Cancer Cells
Sunil Chada, Abner Mhashilkar, Tamra McKenzie, Yanna Liu, Stephen G. Swisher and Kelly Hunt
Mol Ther 9: S255-S256; doi:10.1016/j.ymthe.2004.06.639
676. A Role for Ceramide in AdGFPFasLTET Gene Therapy
James S. Norris, David H. Holman, Ahmed M. El-Zawahry, David A. Schwartz, Alicja Bielawska, Lina M. Obeid, Yusuf A. Hannun and Jian-Yun Dong
Mol Ther 9: S256-S256; doi:10.1016/j.ymthe.2004.06.640
677. Polycationic Liposome-Mediated Extracellular Superoxide Dismutase Gene Delivery Leads to High Levels of the Transgene Expression and Prevents Acute Liver Injury in Mice
Jian Wu, Li Liu, Roy D. Yen, Andrea Catana, Mark A. Zern, Michael H. Nantz and Stefan L. Marklund
Mol Ther 9: S256-S256; doi:10.1016/j.ymthe.2004.06.562
678. Cytoskeleton as the Principal Determinant of the Size-Dependent DNA Mobility in Cytoplasm: A New Barrier for Non-Viral Gene Transfer
Emmanuel Dauty and Alan S. Verkman
Mol Ther 9: S257-S257; doi:10.1016/j.ymthe.2004.06.564
679. Systemic Delivery and Tumor Gene Expression Using Polycation-Precondensed DNA Prepared as Stable Plasmid Lipid Particles
Lorne Palmer, Lloyd B. Jeffs, Kitty P. Y. Chan, Kevin McClintock, Cory Giesbrecht, James Heyes, Amy C. H. Lee and Ian MacLachlan
Mol Ther 9: S257-S257; doi:10.1016/j.ymthe.2004.06.566
680. Lipid-Mediated HSP27 Delivery Improves Functional Recovery Following Moderate Spinal Cord Contusion Injury
Justine J. Overman and Leon L. Hall
Mol Ther 9: S257-S258; doi:10.1016/j.ymthe.2004.06.568
681. Non-Viral DNA and mRNA Gene Delivery to the CNS Pre-Operatively for Neuroprotection and Following Neurotrauma
James G. Hecker, Alice F. Tarantal and Michael H. Nantz
Mol Ther 9: S258-S258; doi:10.1016/j.ymthe.2004.06.570
682. New Histidylated Cationic Lipids for DNA- and mRNA- Based Lipofection
Valluripalli Vinod Kumar, Rajkumar Sunil Singh, Christine Gon|[ccedil]|alves, Pierre Sandrin, Chantal Pichon, Patrick Midoux and Arabinda Chaudhuri
Mol Ther 9: S258-S259; doi:10.1016/j.ymthe.2004.06.572
683. Cationic Mitochondriotropic Vesicles for DNA Delivery to Mitochondria
Volkmar Weissig and Gerard G. M. D'Souza
Mol Ther 9: S259-S259; doi:10.1016/j.ymthe.2004.06.574
684. Expanded Parvoviral Replicons as Novel Nonviral Vectors for Cancer Gene Therapy
Boris R. A. Blechacz, Jean Rommelaere, Christiane Dinsart, Brandenburger Annick and Russell J. Stephen
Mol Ther 9: S259-S260; doi:10.1016/j.ymthe.2004.06.576
685. Epithelium-Specific Gene Therapy Vector Protects Cftr Knockout Mice from Acute Lung Infection
David R. Koehler, Umadevi Sajjan, McKerlie Colin, Allan Coates, Keith Tanswell, Forstner F. Janet and Jim Hu
Mol Ther 9: S260-S260; doi:10.1016/j.ymthe.2004.06.582
686. CAR-Expression Is Essential for Tumor Inititation in Lung Cancer Xenografts
Min Qin, Brian Escuadro, Ling Zhang, Sherven Sharma and Raj K. Batra
Mol Ther 9: S260-S260; doi:10.1016/j.ymthe.2004.06.583
687. Parainfluenza virus-mediated delivery of CFTR to ciliated cells corrects the CF bioelectrical chloride secretory defect and restores the regulation of airway surface liquid depth and mucus transport to cystic fibrosis airway epithelium
L. Zhang, B. Button, M. H. Skiadopoulos, Y. Dang, A. Bukreyev, S. E. Gabriel, P. L. Collins and R. J. Pickles
Mol Ther 9: S260-S261; doi:10.1016/j.ymthe.2004.06.584
688. Pseudotyping FIV-based lentiviral vectors with baculovirus GP64 confers apical entry into airway epithelia
Patrick L. Sinn, Erin R. Burnight, Doug E. Dylla, Christina S. Firm, Melissa A. Hickey, Gary W. Blissard and Paul B. McCray Jr
Mol Ther 9: S261-S261; doi:10.1016/j.ymthe.2004.06.587
689. Protection against pulmonary infection with P. aeruginosa following immunization with an adenovirus vector expressing a P. aeruginosa OprF Epitope
Stefan Worgall, Michael Rivara, Anja Krause, Neil R. Hackett, Peter W. Rovelink, Joseph T. Bruder, Thomas J. Wickham, Imi Kovesdi and Ronald G. Crystal
Mol Ther 9: S261-S262; doi:10.1016/j.ymthe.2004.06.589
690. Angiopoietin-1 Reduces Lung Edema and Mortality Induced by Bacterial Endotoxin
Yao Qi Huang, Harald Sauthoff, Teona Pipiya, Shu Chen, William N. Rom and John G. Hay
Mol Ther 9: S262-S262; doi:10.1016/j.ymthe.2004.06.591
691. CFTR mRNA is expressed in lungs of CFTR-KO mice following administration of adult marrow cells from wild-type donor mice
Kaarin K. Goncz, Roberto Loi, Travis Beckett, Robert Prenovitz and Daniel J. Weiss
Mol Ther 9: S262-S262; doi:10.1016/j.ymthe.2004.06.594
692. A novel AAV vector for the treatment of cystic fibrosis airway disease
Maria Limberis, Guangping Gao, Daniel J. Weiner, Lili Wang, Peter Bell and James M. Wilson
Mol Ther 9: S262-S263; doi:10.1016/j.ymthe.2004.06.598
693. Retrovirally Transduced Bone Marrow Has Effect on Brain Pathology in Mouse Model of Mucopolysaccharidosis IIIB
Yi Zheng, Sergey Ryazantsev, Kazuhiro Ohmi, Huizhi Zhao, Nora Rozengurt, Donald B. Kohn and Elizabeth F. Neufeld
Mol Ther 9: S263-S263; doi:10.1016/j.ymthe.2004.06.608
694. Improved Therapeutic Efficacy Following AAV2/8-Mediated Expression of |[alpha]|-Galactosidase A in Fabry Mice
R. J. Ziegler, C. M. Barbon, C. Li, S. Bercury, M. Cherry and S. H. Cheng
Mol Ther 9: S263-S263; doi:10.1016/j.ymthe.2004.06.644
695. Effect of neonatal hepatic gene therapy on cardiovascular disease, hearing, and visual function in mice with MPS I
Yuli Liu, Hennig Anne, Kovacs Attila, Xu Lingfei, Fu Annabel, Chung Sarah and Ponder Katherine
Mol Ther 9: S264-S264; doi:10.1016/j.ymthe.2004.06.645
696. Comparative study of lentiviral vector-mediated gene therapy in neonatal and young-adult MPS I mice by a single intravenous injection
Hiroshi Kobayashi, Denise Petersen, Denise Carbonaro, Dianne Skelton, Shundi Ge, Carolyn Luzko, Paula Cannon, Maya Otto Dussel, Michael Rosol, Rex Moats, Hiroyuki Shimada and Donald B. Kohn
Mol Ther 9: S264-S264; doi:10.1016/j.ymthe.2004.06.647
697. Correction of lysosomal storage within the brain of adult MPS VII mice following intrahepatic administration of a recombinant adeno-associated virus vector
Kristin Backstrom, Chuansong Wang, Chiou-Miin Wang and Thomas J. Sferra
Mol Ther 9: S265-S265; doi:10.1016/j.ymthe.2004.06.649
698. Gene Therapy of Murine GM1 Gangliosidosis by Genetically Modified Bone Marrow Hematopoietic Progenitor Cells
Renata Sano, Alessandra Tessitore, Angela Ingrassia and Alessandra d'Azzo
Mol Ther 9: S265-S265; doi:10.1016/j.ymthe.2004.06.650
699. Correction of glycogen storage disease type II (GSD II) with an adeno-associated virus 8 (AAV2/8) vector
Baodong Sun, Haoyue Zhang, Luis Franco, Ayn Schneider, Andrew Bird, Andrea Amalfitano, Y.-T. Chen and Dwight D. Koeberl
Mol Ther 9: S265-S266; doi:10.1016/j.ymthe.2004.06.652
700. Targeted delivery of a recombinant protein to neurons and astrocytes by transport and uptake via the low density lipoprotein (LDL) receptor for treatment of neurodegenerative disorders
Brian J. Spencer and Inder M. Verma
Mol Ther 9: S266-S266; doi:10.1016/j.ymthe.2004.06.655
701. A SIN lentiviral vector that allows in vivo drug-selection of hematopoietic stem cells yet retains erythroid-specific expression of the ferrochelatase gene and results in cure of murine protoporphyria
Emmanuel Richard, Elodie Robert, Muriel Cario-Andre, Cecile Ged, Punam Malik, Hubert de Verneuil and Francois Moreau-Gaudry
Mol Ther 9: S266-S267; doi:10.1016/j.ymthe.2004.06.609
702. Successful correction of human beta thalassemia major using a self-inactivating lentiviral vector
G. Puthenveetil, J. Scholes, D. Carbonell, N. Qureshi, P. Xia, L. Zeng, A. Hiti, J.-K. Yee and P. Malik
Mol Ther 9: S267-S267; doi:10.1016/j.ymthe.2004.06.610
703. Efficient in vivo gene marking of hematopoietic cells without marrow conditioning in nonhuman primates
Kyouji Ueda, Yasuji Ueda, Yutaka Hanazonno, Hiroaki Shibata, Naohide Ageyama, Takeyuki Nagashima, Toshiaki Tabata, Akihiro Kume, Susumu Ikehara, Keiji Terao, Keiya Ozawa and Mamoru Hasegawa
Mol Ther 9: S267-S267; doi:10.1016/j.ymthe.2004.06.611
704. Ex vivo and in vivo expansion of HoxB4-Transduced CD34+ cells from dogs, baboons, macaques and humans
Xiao-Bing Zhang, Tobias Neff, Bobbie Thomasson, R. Keith Humphries and Hans-Peter Kiem
Mol Ther 9: S268-S268; doi:10.1016/j.ymthe.2004.06.612
705. AMD3100-Mobilized CD34+ Cells are phenotypically different and better targets for retroviral transduction than G-CSF-mobilized CD34+ Cells in rhesus macaques
Andre Larochelle, Allen Krouse, Donald Orlic, Robert E. Donahue, Cynthia E. Dunbar and Peiman Hematti
Mol Ther 9: S268-S268; doi:10.1016/j.ymthe.2004.06.613
706. Retrovirus integration site distribution in long-term gene-corrected hematopoiesis of the SCID-X1 gene therapy clinical trial
Manfred Schmidt, Jingjong Hu, Salima Hacein-Bey-Abina, Alain Fischer, Manuela Wissler, Claudia Prinz, Hanno Glimm, Kerstin Schwarzwaelder, Francoise LeDeist, Alexandrine Garrigue, Isabelle Andre-Schmutz, Marina Cavazzana-Calvo and Christof von Kalle
Mol Ther 9: S269-S269; doi:10.1016/j.ymthe.2004.06.614
707. Retroviral insertion site analysis in rhesus macaques transplanted with CD34+ hematopoietic stem cells transduced with a simian immunodeficiency virus-based lentiviral vector
Bum Kee Hong, Boris Calmels, Hideki Hanawa, John Gray, Robert E. Donahue, Derek A. Persons, Arthur W. Nienhuis, Peiman Hematti and Cynthia E. Dunbar
Mol Ther 9: S269-S269; doi:10.1016/j.ymthe.2004.06.615
708. Retroviral Vector Integration into the Genome of Rhesus Macaque Long-Term Repopulating Cells
Cole Ferguson, Rima Adler, Stephanie Sellers, Manfred Schmidt, Christof von Kalle, Cynthia Dunbar and Boris Calmels
Mol Ther 9: S270-S270; doi:10.1016/j.ymthe.2004.06.616
709. Gene correction and gene knockouts in human somatic cells using zinc finger nucleases
Matthew H. Porteus
Mol Ther 9: S270-S270; doi:10.1016/j.ymthe.2004.06.726
710. Stem Cell Gene Therapy: Synergizing Improved Gene Repair/Modification and Targeted Integration of Transgenes to Transient In Vivo Topical Minigene Expression
Roger Bertolotti
Mol Ther 9: S271-S271; doi:10.1016/j.ymthe.2004.06.617
711. Trans-splicing correction of CD40 ligand deficiency resulting in naturally regulated correction of a murine model of hyper IgM X-linked immunodeficiency
Minoru Tahara, Robert G. Pergolizzi and Ronald G. Crystal
Mol Ther 9: S271-S271; doi:10.1016/j.ymthe.2004.06.727
712. High Capacity Screen To Select Optimal Pre-trans-splicing Molecules for Trans-splicing Applications
M. Puttaraju, Yanping Yang, Jonathan E. Spindler, Jun Wang, Colette A. Cote, Weng Ke, Garry P. Nolan, S. Gary Mansfield, Lloyd G. Mitchell and Edward Otto
Mol Ther 9: S271-S272; doi:10.1016/j.ymthe.2004.06.618
713. Gene Correction Therapy Using Designed Zinc Finger-Based Endonucleases
Michael C. Holmes, Fyodor D. Urnov, Ya-Li Lee, Jeffrey C. Miller and Philip D. Gregory
Mol Ther 9: S272-S272; doi:10.1016/j.ymthe.2004.06.619
714. Structure-Based Engineering of the FokI DNA Cleavage Domain in the Context of a Chimeric Endonuclease: Towards Maximally Efficient |[ldquo]|Gene Editing|[rdquo]| Therapy
Jeffrey C. Miller, Michael Holmes, Fyodor Urnov, Andrew C. Jamieson and Carl O. Pabo
Mol Ther 9: S272-S272; doi:10.1016/j.ymthe.2004.06.620
715. Artificial Mammalian Gene Networks
Beat P. Kramer, Wilfried Weber and Martin Fussenegger
Mol Ther 9: S272-S273; doi:10.1016/j.ymthe.2004.06.621
716. The Human Norepinephrine Transporter and [11C]-mHED, a Novel Reporter Gene-Tracer Combination for PET Imaging of Gene Therapy
Antoine M. J. Beerens, Anne Rixt Buursma, Marianne G. Rots, Aren van Waarde, Hidde J. Haisma and Erik F. J. de Vries
Mol Ther 9: S273-S273; doi:10.1016/j.ymthe.2004.06.622
717. RNAi Therapy for Dominant Neurodegenerative Diseases
Haibin Xia, Qinwen Mao, Steven L. Eliason, Nathan Kiewiet, Jaime Critchfield, Ines H. Martins, Scott Q. Harper, Xiaohua He, Robert M. Kotin, Huda Y. Zoghbi, Harry T. Orr, Henry L. Paulson and Beverly L. Davidson
Mol Ther 9: S273-S274; doi:10.1016/j.ymthe.2004.06.623
718. Systemic Gene Transfer to Striated Muscles Using rAAV6 Vectors
Paul Gregorevic, Michael J. Blankinship, James M. Allen, Leonard Meuse, Jay Han, Suzanne Oakley and Jeffrey S. Chamberlain
Mol Ther 9: S274-S274; doi:10.1016/j.ymthe.2004.06.624
719. E1-Deleted Adenoviral Vectors Persist in Activated Lymphocytes and Cause Continued Transgene Expression and Stimulation of CD8+ Effector T Cells
Julie Fitzgerald, Arturo Reyes-Sandoval, Nia Tatsis, Scott E. Hensley and Hildegund C. J. Ertl
Mol Ther 9: S274-S274; doi:10.1016/j.ymthe.2004.06.625
720. Tolerisation of Mice To Allow Repeated Administration of Recombinant Sendai Virus Vector to the Airways
Uta Griesenbach, Rosemary Boyton, Luci Somerton, Sara Escudero Garcia, Stefano Ferrari, Toshiyuki Owaki, Shu Tsugumine, Duncan M. Geddes, Mamoru Hasegawa, Danny Altmann and Eric W. F. W. Alton
Mol Ther 9: S274-S275; doi:10.1016/j.ymthe.2004.06.643
721. Proper Maturation of CFTR Protein Expressed by SeV Vector Was Proved by Using a GFP-CFTR Fusion Protein
Hiroshi Ban, Makoto Inoue, Uta Griesenbach, Jun You, Steve C. Hyde, Eric W. F. W. Alton, Akihiro Iida and Mamoru Hasegawa
Mol Ther 9: S275-S275; doi:10.1016/j.ymthe.2004.06.646
722. SeV RNA Replicon Vector: An Efficient Cytoplasmic Expression System Derived from Sendai Virus Self-Replicating Ribonucleoprotein Complexes
Akihiro Iida and Mamoru Hasegawa
Mol Ther 9: S275-S275; doi:10.1016/j.ymthe.2004.06.648
723. Sendai Virus Vectors without All of the Envelop-Related Genes: Successful Recovery and Characterization of the Three Genes (Matrix, Fusion and Hemagglutinin-Neuraminidase)-Deleted Vectors
Makoto Inoue, Mariko Yoshizaki, Yumiko Tokusumi, Takashi Hironaka, Hiroshi Ban, Yoshiyuki Nagai, Akihiro Iida and Mamoru Hasegawa
Mol Ther 9: S275-S276; doi:10.1016/j.ymthe.2004.06.651
724. Engineering of Vesicular Stomatitis Virus-G Protein (VSV-G) To Retarget Recombinant Infectious Retroviral Particles
Hanna S. Dreja and Marc Piechaczyk
Mol Ther 9: S276-S276; doi:10.1016/j.ymthe.2004.06.653
725. Engineering Enhanced Retroviral Vectors by Random Insertion of Functional Peptides
Julie H. Yu and David V. Schaffer
Mol Ther 9: S276-S276; doi:10.1016/j.ymthe.2004.06.654
726. Ultrasound enhances retroviral-mediated gene transfer
Toshio Naka, Tsuyoshi Sakoda, Yoshio Fujioka, Takeshi Tsujino and Mitsumasa Ohyanagi
Mol Ther 9: S277-S277; doi:10.1016/j.ymthe.2004.06.656
727. Baculovirus GP64 Pseudotyped Lentiviral Vectors for Improved Hepatocyte Transduction
David M. Markusic, Ronald Oude-Elferink and Jurgen Seppen
Mol Ther 9: S277-S277; doi:10.1016/j.ymthe.2004.06.657
728. Baculovirus GP64 Pseudotyped Bovine Immunodeficiency Virus-Based Lentiviral Vectors Efficiently Transduce Retinal Cells In Vivo
Rene P. Molina, Hongqing Q. Ye, James Brady, Christine A. Mech, Michael Kaleko and Tianci Luo
Mol Ther 9: S277-S277; doi:10.1016/j.ymthe.2004.06.660
729. Receptor Trafficking Affects the Efficiency of Retrovirus Transduction
Delfi Krishna and Joseph M. Le Doux
Mol Ther 9: S277-S278; doi:10.1016/j.ymthe.2004.06.662
730. Lentiviral Vectors Pseudotyped with Envelope Glycoproteins Derived from Human Parainfluenza Virus Type 3
Cindy Jung, Bradley N. Grzybowski, Suxiang Tong, LiTeng Cheng, Richard W. Compans and Joseph M. Le Doux
Mol Ther 9: S278-S278; doi:10.1016/j.ymthe.2004.06.1011
731. Pseudotyping of Lentiviral Vectors with New Envelope G Proteins from Vesiculoviruses VSV-New Jersey, Chandipura and Piry
Akhil Banerjea and Ramesh Akkina
Mol Ther 9: S278-S278; doi:10.1016/j.ymthe.2004.06.669
732. A Novel Double-Pseudotyped Viral Vector for Gene Therapy
Ning Chai, Gary Kobinger, Giancarlo Tanzi, James Wilson and Paul Bates
Mol Ther 9: S278-S279; doi:10.1016/j.ymthe.2004.06.673
733. Enhancement of Lentiviral-Mediated Gene Transfer in Kidney by Polycations and Detergents
Elena V. Fedorova, Lorenzo Battini, Basil Hanss and G. Luca Gusella
Mol Ther 9: S279-S279; doi:10.1016/j.ymthe.2004.06.674
734. Efficiency of Preloading of Retroviral Vectors without Fibronectin Peptide CH-296 Is Packing Cell Clone Dependent
Claus S. Sondergaard, Christa Haldrup and Lene Pedersen
Mol Ther 9: S279-S279; doi:10.1016/j.ymthe.2004.06.676
735. EIAV-IGF-I Gene Transfer to Motor Neurons Enhances Axonal Length In Vitro
Qinshan Teng, Mary Garrity-Moses, James K. Liu, Diana Tanase, Mimoun Azzouz, Lucy Walmsley, Nicholas D. Mazarakis and Nicholas M. Boulis
Mol Ther 9: S280-S280; doi:10.1016/j.ymthe.2004.06.679
736. Evaluation of an EIAV Gene Therapy Vector for Delivery of Therapeutic Antibodies
Abigail Lamikanra, Kevin A. Myers, Kyri A. Mitrophanous, Susan M. Kingsman and Miles W. Carroll
Mol Ther 9: S280-S280; doi:10.1016/j.ymthe.2004.06.684
737. Development of a Feline Immunodeficiency Virus-Based Lentiviral Vector for Genetic Modification of CNS Neurons
Geoffrey C. Owens, Craig T. Fredrickson and Edward W. Keefer
Mol Ther 9: S280-S280; doi:10.1016/j.ymthe.2004.06.688
738. Optimizing a Lentiviral Vector System for Efficient Transduction of Primary Rat Cardiovascular Cells In Vitro
Jody R. Arsenault, Naoichiro Hattan, William M. Chilian, Kurt J. Varner and Frank Park
Mol Ther 9: S281-S281; doi:10.1016/j.ymthe.2004.06.691
739. Lentiviruses as Gene Transfer Vehicles for Cancer Gene Therapy
Riikka Pellinen, Tanja Hakkarainen, Tiina Pasanen, Kirsi Tulimaki, Anna Ketola, Anni Tenhunen, Pekka Timonen and Jarmo Wahlfors
Mol Ther 9: S281-S281; doi:10.1016/j.ymthe.2004.06.693
740. Replicating Retroviral Vector-Mediated Gene Transfer of the Chemokine, Interferon-Inducible Protein 10 (IP-10) Suppresses Angiogenesis and Tumor Growth in Mice
Yuansheng Sun, Carsten Finger, Luis Alvarez-Vallina, Klaus Cichutek and Christian J. Buchholz
Mol Ther 9: S281-S282; doi:10.1016/j.ymthe.2004.06.702
741. VSV-G Pseudotyped, MLV-Based, Semi-Replication-Competent Retroviruses for Cancer Gene Therapy
Jian Qiao, Jesus Moreno, Michael Forshaw, Rosa M. Diaz and Richard G. Vile
Mol Ther 9: S282-S282; doi:10.1016/j.ymthe.2004.06.703
742. Generation and Evaluation of a New Replication-Competent Retrovirus (RCR) Vector Coding for the SuperCD Suicide Gene
Kai Hauschulz, Stefan Seefried, Andrea Schenk, Irina Smirnow, Wolfgang Wybranietz, Noriyuki Kasahara, Michael Bitzer and Ulrich M. Lauer
Mol Ther 9: S282-S283; doi:10.1016/j.ymthe.2004.06.704
743. Study of Lentiviral Vectors with Two Marker Genes Driven by Two Independent Promoters for Gene Transfer Applications
Marilyne Dijon, Christian Chabannon and Caroline Torne-Celer
Mol Ther 9: S283-S283; doi:10.1016/j.ymthe.2004.06.705
744. Genetic Structure of Adeno-Associated Virus DNA in Human Tissues
Bruce C. Schnepp, Chun-Liang Chen, Ryan L. Jensen, K. Reed Clark and Philip R. Johnson
Mol Ther 9: S283-S283; doi:10.1016/j.ymthe.2004.06.664
745. Innate Immune Responses to Adeno-Associated Virus Vectors
Anne K. Zaiss, Lindsay R. White, Norman C. W. Wong, Jeffrey S. Bartlett and Daniel A. Muruve
Mol Ther 9: S283-S284; doi:10.1016/j.ymthe.2004.06.666
746. Genomic Stability of Self-Complementary Recombinant Adeno-Associated Virus 2 in Mouse Muscle
Changchun Ren, Sanjay Kumar and Selvarangan Ponnazhagan
Mol Ther 9: S284-S284; doi:10.1016/j.ymthe.2004.06.668
747. Direct Labeling and Tracking of Adeno-Associated Virus Single Stranded DNA in AAV Transduction
Bernd Hauck, Wei Zhao and Weidong Xiao
Mol Ther 9: S284-S284; doi:10.1016/j.ymthe.2004.06.1012
748. Generation of Novel Double-Stranded AAV Vectors with an Expanded Packaging Capacity Using Linearized 1-AAV ITR DNA Molecules
Ognjen Petras, Timothy J. Davern and Ryan McTaggart
Mol Ther 9: S284-S285; doi:10.1016/j.ymthe.2004.06.672
749. Adeno-Associated Virus Vectors Integrate at Chromosome Breakage Sites
Daniel G. Miller, Lisa M. Petek and David W. Russell
Mol Ther 9: S285-S285; doi:10.1016/j.ymthe.2004.06.675
750. AAV-2 Vectors and Protease-Activated Receptors: A Potential Interface between Coagulation and Gene Transfer
Jianxiang Zou, Joerg Schuettrumpf, Alexander Schalchterman, Kian W. Tian, Jian-Hua Liu, Patricia Andrade-Gordon and Valder R. Arruda
Mol Ther 9: S285-S285; doi:10.1016/j.ymthe.2004.06.729
751. Breaking Down AAV: Defining the Minimal Capsid Sequences for AAV Function
Yu-Hung Kuo, Jill M. Roberts and Michael G. Kaplitt
Mol Ther 9: S285-S286; doi:10.1016/j.ymthe.2004.06.677
752. Effect of 127 Mutations at 72 Positions on the Surface of Adeno-Associated Virus Type-2
Michael Lochrie, Gwen Tatsuno, Jennifer Wellman, Shang-zhen Zhou, Richard Surosky, Glenn Pierce and Peter Colosi
Mol Ther 9: S286-S286; doi:10.1016/j.ymthe.2004.06.678
753. Evaluation of AAV Neutralizing Antibodies Using a Passive Immunity Model in SCID Mice
Ciaran D. Scallan, Tongyao Liu, Susannah Patarroyo-White, Haiyan Jiang, Shangzhen Zhou, Glenn Pierce and Linda B. Couto
Mol Ther 9: S286-S286; doi:10.1016/j.ymthe.2004.06.681
754. Intracellular Trafficking Patterns of rAAV-2 Demonstrate Significant Cell-Type Specificity
Wei Ding, Neal Zhang, Ziying Yan, Richard Peluso, Barrie Carter and John F. Engelhardt
Mol Ther 9: S287-S287; doi:10.1016/j.ymthe.2004.06.683
755. Cytoplasmic Dynein-Dependent Adeno-Associated Virus Interaction with Microtubules
Samir Kelkar, Ronald G. Crystal and Philip L. Leopold
Mol Ther 9: S287-S287; doi:10.1016/j.ymthe.2004.06.686
756. Distinct Classes of Proteasome-Modulating Agents Cooperatively Augment Recombinant Adeno-Associated Virus Type 2 and Type 5-Mediated Transduction from the Apical Surface of Human Airway Epithelia
Ziying Yan, Roman Zak, Yulong Zhang, Wei Ding, Simon Godwin, Keith Munson, Richard Peluso and John F. Engelhardt
Mol Ther 9: S287-S288; doi:10.1016/j.ymthe.2004.06.689
757. Enhancement of Gene Expression by a Recombinant Adeno-Associated Virus by Various Chemical Treatments
Sung Jin Kim, Young Ran Nam, Chul-Hyen Joo, Jin Woo Chang, Yoo-Kyum Kim and Heuiran Lee
Mol Ther 9: S288-S288; doi:10.1016/j.ymthe.2004.06.695
758. A Histone Deacetylase Inhibitor Enhances Recombinant Adeno-Associated Virus-Mediated Gene Expression in Cancer Cells In Vitro and In Vivo
Takashi Okada, Tatsuya Nomoto, Yuhe Liu, Mayumi Iwata-Okada, Masafumi Takahashi, Kuniko Shimazaki, Takashi Matsushita, Hiroaki Mizukami, Akihiro Kume and Keiya Ozawa
Mol Ther 9: S288-S289; doi:10.1016/j.ymthe.2004.06.754
759. The DNA Minor Groove Binding Agents Hoechst 33258 and 33342 Enhance Recombinant Adeno-Associated Virus (rAAV) Transgene Expression
Lina Li, Linda Yang and Robert M. Kotin
Mol Ther 9: S289-S289; doi:10.1016/j.ymthe.2004.06.755
760. Dual Therapeutic Utility of Proteasome Modulating Agents for Pharmico-Gene Therapy of the Cystic Fibrosis Airway
Liang N. Zhang, Phil Karp, Christopher J. Gerard, Eric Pastor, Keith Munson, Ziying Yan, Simon Godwin, Joseph Zabner, Richard Peluso, Barrie Carter and John F. Engelhardt
Mol Ther 9: S289-S289; doi:10.1016/j.ymthe.2004.06.756
761. Targeting DNA-PK by siRNA to Study AAV Replication
Young-Kook Choi, Barry J. Byrne and Sihong Song
Mol Ther 9: S289-S289; doi:10.1016/j.ymthe.2004.06.757
762. Human Papillomavirus Type 16 Helper Functions for Adeno-Associated Virus Type 2 Replication
Paul L. Hermonat, Yong Liu, Jawahar L. Mehta and Hong You
Mol Ther 9: S289-S290; doi:10.1016/j.ymthe.2004.06.758
763. Size-Dependent Packaging and Transgene Expression of Double-Stranded AAV Vectors
Zhong Wang, gregory szeto, Jian Zhang, Juan Li and Xiao Xiao
Mol Ther 9: S290-S290; doi:10.1016/j.ymthe.2004.06.759
764. Role of Actin Cytoskeleton and Small GTPase Rap1 in the Co-Receptor Activity of Activated |[alpha]|5|[beta]|1 Integrin for Human Parvovirus B19 Entry
Kirsten A. Weigel-Kelley and Arun Srivastava
Mol Ther 9: S290-S290; doi:10.1016/j.ymthe.2004.06.760
765. The Efficacy of Adenovirus Vector-Mediated Gene Transfer into Human Osteoblasts In Vitro and Osseous Tissue In Vivo
Keun Bae Lee, Charles L. Saltzman, Peter Taft, Michael Klotz and Joseph Zabner
Mol Ther 9: S290-S291; doi:10.1016/j.ymthe.2004.06.680
766. Human Hematopoietic (CD34+) Stem Cells Possess High Affinity Receptors for Adenovirus Type 11p
Ya-Fang Mei, Anna Segerman, Kristina Lindman, Per H|[ouml]|rnsten, Anders Wahlin and G|[ouml]|ran Wadell
Mol Ther 9: S291-S291; doi:10.1016/j.ymthe.2004.06.682
767. Intact Microtubules Are Required for Ad-Vector Induction of Chemokine Genes in Epithelial Cells
Daniel A. Muruve and Lindsay R. White
Mol Ther 9: S291-S291; doi:10.1016/j.ymthe.2004.06.685
768. Activity of the Extracellular Domain of the Coxsackie and Adenovirus Receptor
Katherine J. D. A. Excoffon, Geri L. Traver, Nicholas Gansemer and Joseph Zabner
Mol Ther 9: S291-S292; doi:10.1016/j.ymthe.2004.06.687
769. Microvessel Injury in Irradiation Damage in Salivary Glands
Ana Paola Cotrim, Corinne M. Goldsmith, Anastasia L. Sowers, James B. Mitchell and Bruce J. Baum
Mol Ther 9: S292-S292; doi:10.1016/j.ymthe.2004.06.690
770. Pharmacogenetics of Adenoviruses
Pierre Lefesvre and Dirk van Bekkum
Mol Ther 9: S292-S292; doi:10.1016/j.ymthe.2004.06.692
771. Adenovirus-Mediated siRNA Against Survivin Enhanced Sensitivity to Paclitaxel-Induced Apoptosis in MCF-7 Cells
Toshihiro Tanaka, Hiroaki Uchida, Katsunori Sasaki, Makoto Miyagishi, Kazunari Taira and Hirofumi Hamada
Mol Ther 9: S292-S293; doi:10.1016/j.ymthe.2004.06.694
772. Adenoviral-Mediated Antioxidant Gene Transfer: A Gene Therapy Approach towards Diminishing Pancreatic |[beta]|-Cell Susceptibility to Cytokine-Induced Oxidative Damage
Cillian T. McCabe and Timothy O'Brien
Mol Ther 9: S293-S293; doi:10.1016/j.ymthe.2004.06.696
773. Non-Invasive In Vivo Detection of Episomes Delivered to Mouse Hepatocytes by a Helper Dependent Adenovirus- Epstein-Barr Virus Hybrid Vector System
Sean D. Gallaher, Jose S. Gil, Oliver Dorigo and Arnold J. Berk
Mol Ther 9: S293-S294; doi:10.1016/j.ymthe.2004.06.697
774. Stability Study of an Adenoviral Vector Prepared in GTS: The Buffer Formulation of the Adenovirus Reference Material
Renald Gilbert, Francois Bouthillier and Bernard Massie
Mol Ther 9: S294-S294; doi:10.1016/j.ymthe.2004.06.698
775. An Novel Adenoviral E1 Complementary Cell for Eliminating Replication Competent Adenovirus (RCA) during Viral Production
Deborah Farson, Lucy Tao, Derek Ko, Thomas Harding, De-Chao Yu and Yuanhao Li
Mol Ther 9: S294-S294; doi:10.1016/j.ymthe.2004.06.699
776. Adenoviral Mediated Gene Transfer of NOS Isoforms and Vascular Cell Proliferation
Ronan Cooney and Timothy O'Brien
Mol Ther 9: S294-S295; doi:10.1016/j.ymthe.2004.06.700
777. Inactivated Adenoviral Vectors with a Conditional Infectivity
Mark W. Pandori and Takeshi Sano
Mol Ther 9: S295-S295; doi:10.1016/j.ymthe.2004.06.701
778. Rapid Adenoviral Neutralization Assay
Edward C. Nwanegbo, Wentao Gao, Simon Barret-Boyes, Paul D. Robbins and Andrea Gambotto
Mol Ther 9: S295-S295; doi:10.1016/j.ymthe.2004.06.868
779. High-Capacity Adenovirus/ Retrotransposon Hybrid Vectors for Efficient and Stable Gene Transfer
Shuji Kubo, Harris Soifer, John V. Moran, Haig H. Kazazian Jr. and Nori Kasahara
Mol Ther 9: S295-S295; doi:10.1016/j.ymthe.2004.06.869
780. Efficient Adenovirus-Mediated Human Interferon-gamma Transfer into C6 Glioma Cells
Lizhi Wu, Xiuju Wu and Wenlin Huang
Mol Ther 9: S295-S296; doi:10.1016/j.ymthe.2004.06.870
781. Quantification of Empty Capsids in Preparations of Conditionally Replicating Adenovirus
Sundari Ravindran, Xiaoyu Yang, Suganto Sutjipto, Yan-Hui Liu and Gary Vellekamp
Mol Ther 9: S296-S296; doi:10.1016/j.ymthe.2004.06.871
782. Genetic Labeling of Adenovirus with Red Fluorescent Proteins on pIX for Vector Detection
Long P. Le, Igor P. Dmitriev, Julia G. Davydova, Masato Yamamoto and David T. Curiel
Mol Ther 9: S296-S296; doi:10.1016/j.ymthe.2004.06.872
783. Compared Stability and Antitumour Activity of Recombinant Endostatin Protein Expressed in Yeast with Recombinant Adenovirus Carrying Endostatin Gene
Zhihui Liang, Jialin Huang and wenlin Huang
Mol Ther 9: S296-S297; doi:10.1016/j.ymthe.2004.06.873
784. An AdEASY Based Cloning System for Generating Adenoviral Vectors That Express Transgenes Late in the Viral Life Cycle
Michael Lie-A-Ling, Conny Bakker, John G. Wesseling and Piter J. Bosma
Mol Ther 9: S297-S297; doi:10.1016/j.ymthe.2004.06.874
785. Synergism of Combined Radiation and Suicide Gene Therapy Using a Chimeric Adenovirus Vector for Bladder Cancer
Kazumasa Matsumoto, Christian T. F. Freund, Weiguo Jian, Jiang Yu, Patricia Yotnda, Alan R. Davis and Seth P. Lerner
Mol Ther 9: S297-S297; doi:10.1016/j.ymthe.2004.06.875
786. Genetic Labeling of Adenovirus with Luciferase on pIX for Vector Detection
Long P. Le, Igor P. Dmitriev, Julia G. Davydova, Masato Yamamoto and David T. Curiel
Mol Ther 9: S297-S298; doi:10.1016/j.ymthe.2004.06.876
787. Cationic Lipids Improve Transfection Efficacy of Recombinant Replication Deficient Adenovirus in Cutaneous Cells
Frank Jacobsen, Tobias Hirsch, Dominik Mittler, Hans Ulrich Steinau and Lars Steinstraesser
Mol Ther 9: S298-S299; doi:10.1016/j.ymthe.2004.06.877
788. Imaging of Adenoviral Replication with a Fluorescent Reporter in the E3 Region
Hidetaka A. Ono, Long P. Le, Julia G. Davydova, Tatyana Gavrikova, Pedro J. Ramirez, Hiroshi Shimada, David T. Curiel and Masato Yamamoto
Mol Ther 9: S299-S299; doi:10.1016/j.ymthe.2004.06.878
789. Hydrodynamic Injection of Helper Dependent Adenoviral Vectors Increases Liver Transduction Efficiency and Decreases Acute Inflammatory Response
Nicola Brunetti|[ndash]|Pierri, Viraj Mane, Donna Palmer, Arthur L. Beaudet and Philip Ng
Mol Ther 9: S299-S299; doi:10.1016/j.ymthe.2004.06.879
790. Regulatable Transgene Expression from Gutless Adenoviral Vectors
Shyam Goverdhana, Weidong Xiong, Diana S. Greengold, James Curtin, Eric Soffer, Pedro R. Lowenstein and Maria G. Castro
Mol Ther 9: S299-S300; doi:10.1016/j.ymthe.2004.06.880
791. Histone Deacetylase Inhibition Up-Regulates CAR and Increases Adenovirus Infection and Transgene Expression in Skeletal Muscle
Alan R. Brooks, Linda Cashion, Kaye Reiter, Peiyin Wang, Hu Sheng Qian, Richard N. Harkins and Gabor M. Rubanyi
Mol Ther 9: S300-S300; doi:10.1016/j.ymthe.2004.06.881
792. Dynamic High Capacity MUSTANG|[reg]| Q Membrane Units for Scaleable Anion Exchange Chromatography Purification of Adenoviral Vectors
Robert H. Kutner, Ajay Lajmi and Jakob Reiser
Mol Ther 9: S300-S300; doi:10.1016/j.ymthe.2004.06.882
793. Adenopure LS|[trade]| Large Scale Kit for Purification of Recombinant Adenovirus
Timothy D. Kierstead, Tawfiq Hazboun and Anthony P. Green
Mol Ther 9: S300-S301; doi:10.1016/j.ymthe.2004.06.883
794. Immobilized Cobalt Affinity Chromatography Provides a Novel, Efficient Method for HSV Gene Vector Purification
Canping Jiang, James B. Wechuck, William F. Goins, David M. Krisky, Darren P. Wolfe, Mohammad M. Ataai and Joseph C. Glorioso
Mol Ther 9: S301-S301; doi:10.1016/j.ymthe.2004.06.833
795. Highly Purified, In Vitro Constructed SV40 Vectors for In Vivo Gene Delivery
Santanu Mukherjee, Michal Bronstein, Mahmoud Abd-El-Latif, Orly Ben-nun-Shaul and Ariella Oppenheim
Mol Ther 9: S301-S301; doi:10.1016/j.ymthe.2004.06.834
796. The HSV-1 iBAC Amplicon Vector for Functional Genomics Studies into the Genetic Mechanisms of Neurodegenerative Disease
S. E. Lawler, S. Senior, M. Ingelsson, Y. Saeki, B. T. Hyman, A. P. Monaco, E. A. Chiocca and R. Wade-Martins
Mol Ther 9: S301-S302; doi:10.1016/j.ymthe.2004.06.835
797. A Trans-Dominant Negative and Replication Defective HSV-1 Vector for In Vivo and Ex Vivo Gene Transfer
Christoph F. P. Theopold, Daniela Hoeller and Feng Yao
Mol Ther 9: S302-S302; doi:10.1016/j.ymthe.2004.06.836
798. Intracarotid Delivery of Oncolytic Herpes Simplex Virus-1 G47|[Delta]| to Metastatic Breast Cancer in the Brain
Renbin Liu, Robert L. Martuza and Samuel D. Rabkin
Mol Ther 9: S302-S303; doi:10.1016/j.ymthe.2004.06.837
799. Initial Characterization of a Super-Permissive Cell Line for Adeno-Associated Virus (AAV): Microarray-Intimated CK2 Helps AAV Replication
Hong You, Yong Liu, Jawahar L. Mehta and Paul L. Hermonat
Mol Ther 9: S303-S303; doi:10.1016/j.ymthe.2004.06.838
800. Generation of Recombinant Skin In Vitro by Adeno-Associated Virus Type 2 Vector Transduction
Nalini Agrawal, Yong Liu, Jawahar L. Mehta, Hong You and Paul L. Hermonat
Mol Ther 9: S303-S303; doi:10.1016/j.ymthe.2004.06.839
801. Novel Targeting Non-AAV Parvoviral Vectors for Gene Therapy
Refael Itah, Igor Etingov, Clay Davis and Jacov Tal
Mol Ther 9: S303-S304; doi:10.1016/j.ymthe.2004.06.840
802. Rapid Conversion of HSV Resistant Cells to Sensitive Cells Using AdV-Mediated Overexpression of HSV Receptors
Shinji Yamamoto, Edyta Tyminski, E. A. Chiocca and Yoshinaga Saeki
Mol Ther 9: S304-S304; doi:10.1016/j.ymthe.2004.06.841
803. Functional Analysis of Various Gene Linkers Serving Proportional Coexpression of PET Marker and Therapeutic Genes
Alexandra Winkeler, Markus Hartung, Mark Slack and Andreas H. Jacobs
Mol Ther 9: S304-S305; doi:10.1016/j.ymthe.2004.06.842
804. Expression of Green Fluorescent Protein Modifies the Antitumor Effect of Oncolytic HSV-1 Vectors
Yasushi Ino, Yoshinaga Saeki, E. Antonio Chiocca and Tomoki Todo
Mol Ther 9: S305-S305; doi:10.1016/j.ymthe.2004.06.843
805. Efficient Transduction of Human Cord Blood and Adult Peripheral Blood CD34+ Progenitors with HSV-1 Derived Amplicon Vectors
Martin Krahn, Anne-Marie Imbert, Catherine Badens, Cecile Zaupa, Alberto Epstein, Christian Chabannon and Michel Fontes
Mol Ther 9: S305-S305; doi:10.1016/j.ymthe.2004.06.844
806. HSV Based Genetic Selection System for Identification of Pain Signaling Regulators
Rahul Srinivasan, Darren Wolfe, Shaohua Huang, David Krisky and Joseph Glorioso
Mol Ther 9: S305-S306; doi:10.1016/j.ymthe.2004.06.845
807. Hyper-Attenuated Vaccine Strain of Vaccinia Virus
Bela Denes, Daila S. Gridley, Tatyana Timiryasova, Nadja Fodor, Zsuzsanna Takatsy and Istvan Fodor
Mol Ther 9: S306-S306; doi:10.1016/j.ymthe.2004.06.846
808. Electro-Tranfection of Epstein-Barr Virus LMP-2 Specific TCRs Provides a Non-Viral Means To Transfer Antigen Specific T-Cell Receptors to Activated PBMC Populations
Lisa Jurgens, Jill Gershan, James Weber and Rimas Orentas
Mol Ther 9: S306-S306; doi:10.1016/j.ymthe.2004.06.706
809. PhiC31 Integrase Mediates Site-Specific Genomic Integration in Rabbit Cells and Rabbit Knee Joints
Annahita Keravala, Joan Nash, Joylette L. Portlock, Paul D. Robbins and Michele P. Calos
Mol Ther 9: S306-S307; doi:10.1016/j.ymthe.2004.06.707
810. Site-Specific Integration Enhances Expression of DNA Introduced into Skeletal Muscle
Thurman M. Wheeler, Sohail Jarrahian, Carmen Bertoni, Eric C. Olivares, Timothy Doyle, Christopher H. Contag, Michele P. Calos and Thomas A. Rando
Mol Ther 9: S307-S307; doi:10.1016/j.ymthe.2004.06.708
811. The Hotspots of Integration Targeted by the Site-Specific Integrase PhiC31 May Be Cell Line Dependent
Anja Ehrhardt, Jeffrey A. Engler, Michele P. Calos and Mark A. Kay
Mol Ther 9: S307-S307; doi:10.1016/j.ymthe.2004.06.709
812. Hydroporation as the Mechanism Accounting for Efficient Gene Transfer by Hydrodynamic Delivery
Dexi Liu, Guisheng Zhang, Xiang Gao, Young K. Song, Regis Vollmer, Donna B. Stolz, Joshua Z. Gasiorowski and David A. Dean
Mol Ther 9: S307-S308; doi:10.1016/j.ymthe.2004.06.710
813. Ecdysone Receptor-Based Inducible Gene Regulation System for Simultaneous Regulation of Multiple Genes
Prasanna Kumar, Anand K. Katakam, Subba R. Palli, Mohan Kumar, Henry Hoff III and Dean E. Cress
Mol Ther 9: S308-S308; doi:10.1016/j.ymthe.2004.06.711
814. Integration Sites Used by the PhiC31 Site-Specific Integrase in the Human Genome
Thomas W. Chalberg, Daniel S. Ginsburg, Patrick J. Kirby, Eric C. Olivares, Joylette L. Portlock, Bhaskar Thyagarajan and Michele P. Calos
Mol Ther 9: S308-S308; doi:10.1016/j.ymthe.2004.06.712
815. Investigation into the Frequency of Post-Integrative Gene Silencing Using a Non-Selective Sleeping Beauty Transposition System
Brian S. Garrison, Stephen R. Yant, Jacob G. Mikkelsen and Mark A. Kay
Mol Ther 9: S309-S309; doi:10.1016/j.ymthe.2004.06.713
816. Development of Potent DNA Vaccines by Coupling of Linear MIDGE Vectors to Peptides
Sonia Moreno, Florian Sack, Colin Smith, Luisa Lopez-Fuertes, Antonio J. Vila-Coro, Sven A. K|[ouml]|nig-Merediz, Burghardt Wittig, Matthias Schroff, Manuel Schmidt and Marcos Timon
Mol Ther 9: S309-S309; doi:10.1016/j.ymthe.2004.06.714
817. Nonrandom Insertion Site Preferences for the SB Transposon In Vitro and In Vivo
Stephen R. Yant, Xiaolin Wu, Yong Huang, Bernie Daigle, Brian A. Garrison, Shawn M. Burgess and Mark A. Kay
Mol Ther 9: S309-S310; doi:10.1016/j.ymthe.2004.06.715
818. Optimization of E. coli Fermentation for Plasmid DNA Production
Aaron Carnes, Clague Hodgson and Jim Williams
Mol Ther 9: S310-S310; doi:10.1016/j.ymthe.2004.06.716
819. Hyperactive Transposase Mutants of the Sleeping Beauty Transposon
Stephen R. Yant, Julie Park, Yong Huang, Jacob Giehm Mikkelsen and Mark A. Kay
Mol Ther 9: S310-S310; doi:10.1016/j.ymthe.2004.06.717
820. Cost-Effective, Pharmaceutical-Grade Plasmid Production Method for Commercial Use
Henry Hebel, Sriram Ramakrishnan, Hugo Gonzalez and Heather Attra
Mol Ther 9: S310-S311; doi:10.1016/j.ymthe.2004.06.718
821. A Potential Therapeutic Angiogenesis Using a Naked DNA Containing Angiogenin cDNA
Keerang Park, Soo-Ik Chang, Young-Ill Lee, Heesoon Chang, Young-Hwa Cho, Bong-Su Kang, Jeong-Eun Lee, Ji-Eun Yun and Hyun Park
Mol Ther 9: S311-S311; doi:10.1016/j.ymthe.2004.06.719
822. Efficient Delivery of Plasmid DNA to Murine Skin Using In Vivo Electroporation
Richard Heller, Mark J. Jaroszeski, Loree C. Heller, Kathleen Merkler, Andrea N. McCray and Richard A. Gilbert
Mol Ther 9: S311-S312; doi:10.1016/j.ymthe.2004.06.724
823. Use of a Cre Recombinase Silencing Strategy to Characterize Sleeping Beauty-Mediated Transposition In Vivo
Paul R. Score, Joel L. Frandsen, Jennifer L. Geurts, Perry B. Hackett, David A. Largaespada and R.Scott McIvor
Mol Ther 9: S312-S312; doi:10.1016/j.ymthe.2004.06.720
824. Duration of Expression of Sleeping Beauty Transposase by Hydrodynamic Injection of C57/BL6 Mice
Jason B. Bell, Andrew C. Wilber, Elena L. Aronovich, John R. Ohlfest, Brenda L. Koniar, David A. Largaespada, R. Scott McIvor and Perry B. Hackett
Mol Ther 9: S312-S312; doi:10.1016/j.ymthe.2004.06.721
825. Downstream Processing of Supercoiled Plasmid DNA
Lena M. Sandberg, Annika Andersson, Jozsef Vasi, Marianne Sparrman, Emma H|[aring]|kansson, Per Nilsson and Raf Lemmens
Mol Ther 9: S312-S313; doi:10.1016/j.ymthe.2004.06.722
826. Non-Viral Gene Therapy Targeting Fanconi Anemia Hematopoietic Stem Cells: A Realistic Hope?
Meenakshi Noll, Ryan Bennett, Stephen Yant, Jacob G. Mikkelsen, Cindy Chen, Mark A. Kay and Markus Grompe
Mol Ther 9: S313-S313; doi:10.1016/j.ymthe.2004.06.723
827. A Novel Bone Gene Therapy Platform Based on Nonvirally Transfected Human Mesenchymal Stem Cells
Hadi Aslan, Tamar Azoulay, Yoram Zilberman, Gadi Pelled, Jinzhong Li, Gregory A. Helm, Zulma Gazit and Dan Gazit
Mol Ther 9: S313-S314; doi:10.1016/j.ymthe.2004.06.725
828. Evaluation of Non-Viral Vectors for Gene Therapy of Hemophilia A
Katherine Bowman, Rita Sarkar, Xuli Wang, Hai-Quan Mao and Kam W. Leong
Mol Ther 9: S314-S314; doi:10.1016/j.ymthe.2004.06.728
829. Preferential Transfection of Tissue Macrophages Following Intravenous Administration of sec-R Targeted hCFTR DNA Enhances Survival of CF Mice Inoculated with Pseudomonas aeruginosa Agar Beads
Assem G. Ziady, James Poleman, Christiaan van Heeckeren, Anna van Heeckeren and Pamela B. Davis
Mol Ther 9: S314-S314; doi:10.1016/j.ymthe.2004.06.730
830. Efficient Transfer of Synthetic Small Interfering RNAs Through Atelocollagen-Mediated Delivery System
Shunji Nagahara, Yoshiko Minakuchi, Fumitaka Takeshita, Kimi Honma, Koji Hanai, Akihiko Sano and Takahiro Ochiya
Mol Ther 9: S315-S315; doi:10.1016/j.ymthe.2004.06.731
831. Biodistribution of DNA-Complex of Dendritic Poly(L-Lysine) after Intravenous Injection
Takahito Kawano, Tatsuya Okuda and Takuro Niidome
Mol Ther 9: S315-S315; doi:10.1016/j.ymthe.2004.06.732
832. Radioscintigraphy of sec-R Directed CFTR Gene Transfer in CF Mice Following Intranasal Administration
Assem G. Ziady, Gregory Wojtkicwicz, Pamela B. Davis and Zhenghong Lee
Mol Ther 9: S315-S316; doi:10.1016/j.ymthe.2004.06.733
833. Metabolically Stabilized Non-Viral Gene Delivery Systems
Dijie Liu, Molly E. Martin, Changpo Chen and Kevin G. Rice
Mol Ther 9: S316-S316; doi:10.1016/j.ymthe.2004.06.734
834. Tumor Targeted Gene Delivery Using a Non-Viral Vector System
Puthupparampil V. Scaria, Raymond M. Schiffelers, Aslam Ansari, Gert Storm, Qin Zhou and Martin Woodle
Mol Ther 9: S316-S317; doi:10.1016/j.ymthe.2004.06.735
835. Macropinocytosis of Polyplexes and Recycling of Plasmid from Clathrin-Dependent Pathway Impair the Transfection Efficiency into Human Hepatocarcinoma Cells
Christine Gon|[ccedil]|alves, Eric Mennesson, Renate Fuchs, Jean-Pierre Gorvel, Patrick Midoux and Chantal Pichon
Mol Ther 9: S317-S317; doi:10.1016/j.ymthe.2004.06.736
836. Transendothelial Transport Studies of Polymer-Based Gene Delivery Systems
Eric Mennesson, Pierre Sandrin, Claudine Kieda, Patrick Erbacher, Patrick Midoux and Chantal Pichon
Mol Ther 9: S317-S317; doi:10.1016/j.ymthe.2004.06.737
837. Polyethylenimine/Albumin Complexes Display High Transfection Efficiency in Confluent and Polarized Human Respiratory Epithelial Cells
Salvatore Carrabino and Massimo Conese
Mol Ther 9: S317-S318; doi:10.1016/j.ymthe.2004.06.738
838. PEI-Chitosan Graft Copolymers for Mucosal Delivery of Genetic Vaccines
Sudhir P. Kasturi and Krishnendu Roy
Mol Ther 9: S318-S318; doi:10.1016/j.ymthe.2004.06.739
839. The Effect of PEGylation on Polyplexes Containing Ligands: Morphology and Binding Efficiency
Yan Guo, Jianren Gu and Yuhong Xu
Mol Ther 9: S318-S318; doi:10.1016/j.ymthe.2004.06.740
840. Novel Receptor-Mediated Gene Transfection Systems Comprising Plasmid / Polycation / RGD-PEG-COOH Ternary Complexes
Mitsuko Sakae, Tomoko Ito, Naoko Iida Tanaka, Takuro Niidome, Hironobu Yanagie and Yoshiyuki Koyama
Mol Ther 9: S319-S319; doi:10.1016/j.ymthe.2004.06.741
841. Cysteine-Flanked Melittin Analogues as Lysotropic Gene Delivery Vectors
Chang-Po Chen, Ji-seon Kim and Kevin G. Rice
Mol Ther 9: S319-S319; doi:10.1016/j.ymthe.2004.06.742
842. Cell Permeable Peptides: Potential Use To Enhance Intracellular Gene Delivery
Miguel Mano, Paula Verissimo, Carlos Faro, Abraham Loyter, Sergio Simoes and Maria C. Pedroso de Lima
Mol Ther 9: S320-S320; doi:10.1016/j.ymthe.2004.06.743
843. Single-Chain Polypeptide: Universal Module for Targeted Gene Delivery
Valentina A. Anisimova and Igor G. Shemyakin
Mol Ther 9: S320-S320; doi:10.1016/j.ymthe.2004.06.744
844. Novel Pathways of Cell Entry and Trafficking Utilized by Ad Capsid Proteins in the Absence of the Whole Virus
Altan Rentsendorj, Hasmik Agadjanian, Maguire Meghan, Jiansong Xie, Xinhua Chen, Michelle MacVeigh, Hamm-Alvarez Sarah and Lali K. Medina-Kauwe
Mol Ther 9: S320-S321; doi:10.1016/j.ymthe.2004.06.745
845. Enhanced Efficacy of Radiation Sensitivity by Controlled Gene Delivery of PTEN Expression Vector Conjugated with Cationized Gelatin in Prostate Cancer Cells
Yoshiaki Matsumura, Satoshi Takada, Satoshi Anai, Motoyoshi Tanaka, Hirotsugu Uemura and Yoshihiko Hirao
Mol Ther 9: S321-S321; doi:10.1016/j.ymthe.2004.06.746
846. Copolymer-Protected Vector Mediated BMP-2 Gene Delivery to Articular Chondrocytes in a 3-Dimensional Injectable Fibrin Matrix for Tissue Engineering
Ulrike Schillinger, Gabi Wexel, Christian Hacker, Martin Kullmer, Axel Stemberger and Christian Plank
Mol Ther 9: S321-S321; doi:10.1016/j.ymthe.2004.06.747
847. Hyaluronic Acid as a Self-Assembled Coating of Plasmid/Polycation Complexes for Cell-Specific Gene Delivery
Tomoko Ito, Naoko Iida Tanaka, Toshinori Sato, Zhihong Yang, Takuro Niidome, Takahito Kawano and Yoshiyuki Koyama
Mol Ther 9: S321-S322; doi:10.1016/j.ymthe.2004.06.748
848. The Study on the VEGF Plasmids Purify by Magnetic Nanoparticles
Minli Sun, Hao Zhang and Baigen Zhang
Mol Ther 9: S322-S322; doi:10.1016/j.ymthe.2004.06.749
849. CD Spectra of Compacted DNA Nanoparticles Demonstrate a Unique DNA Structure
Tomasz H. Kowalczyk, Christopher R. Gedeon, Patrick J. Klepcyk, Sharon M. Oette, Tamara L. Fink, Robert C. Moen and Mark J. Cooper
Mol Ther 9: S322-S322; doi:10.1016/j.ymthe.2004.06.750
850. Quantitative Analysis of Non-Viral Gene Therapy in a Three-Dimensional Liver Tissue Construct
Nathan C. Tedford, David W. Jackson, Karel Domansky, Linda G. Griffith and Douglas A. Lauffenburger
Mol Ther 9: S323-S323; doi:10.1016/j.ymthe.2004.06.751
851. Development of Brain Tumor Organ Cultures for Characterizing Polymer/Plasmid DNA Mediated Gene Transfer
Nathalie Y. Toussaint, Sean Kearns, Bjorn Scheffler, Ronald Mandel and Sean M. Sullivan
Mol Ther 9: S323-S323; doi:10.1016/j.ymthe.2004.06.752
852. Development of Systemic Non-Viral Gene Delivery Systems: Cationic Nanogels
Serguei V. Vinogradov and Alexander V. Kabanov
Mol Ther 9: S323-S324; doi:10.1016/j.ymthe.2004.06.753
853. Efficacy of AAV-Mediated Expression of Acid Sphingomyelinase at Correcting the Visceral and Pulmonary Manifestations of Niemann-Pick B Disease
C. M. Barbon, R. J. Ziegler, S. D. Bercury, M. Cherry, C. Li, E. Schuchman, R. J. Desnick, M. J. Lukason, S. Lonning and S. H. Cheng
Mol Ther 9: S324-S324; doi:10.1016/j.ymthe.2004.06.761
854. Feasibility of AAV-Mediated Gene Therapy Examined Using a New Murine Model (D409V/null) of Gaucher Disease
John Marshall, Kerry McEachern, Jennifer B. Nietupski, Julie A. Cavanagh Kyros, Donna Armentano, Gregory A. Grabowski and Seng H. Cheng
Mol Ther 9: S324-S325; doi:10.1016/j.ymthe.2004.06.762
855. Stable Transduction of Hepatocytes Following Intravenous Retroviral Gene Therapy in Seven-Week-Old Dogs with Mucopolysaccharidosis (MPS) VII
Mark Haskins, Thomas O'Malley, N. Matthew Ellinwood, Patricia O'Donnell, Kristen Cullen, Karyn Cullen, Margaret Sleeper, Gustavo Aguirre, Lingfie Xu, Ping Wang and Katherine Ponder
Mol Ther 9: S325-S325; doi:10.1016/j.ymthe.2004.06.763
856. Neonatal Liver-Directed Gene Therapy Markedly Reduces Bone Disease in MPS I
Yuli Liu, Mango Robert, Lingfei Xu, Deborah Novack, Clay Semenkovich, Trey Coleman and Katherine Ponder
Mol Ther 9: S325-S325; doi:10.1016/j.ymthe.2004.06.764
857. Intravenous Retroviral Gene Therapy in Neonatal Mucopolysaccharidosis VI Cats
Thomas M. O'Malley, YuLi Liu, Patty A. O'Donnell, Karyn J. Cullen, Ping Wang, Kristen J. Cullen, Gustavo D. Aguirre, Katherine P. Ponder and Mark E. Haskins
Mol Ther 9: S326-S326; doi:10.1016/j.ymthe.2004.06.765
858. Correction of the CNS Pathology and Function of MPS VII Mice by Intraventricular Transplantation of Genetically Modified Bone Marrow Stromal Cells
Ken Sakurai, Sayoko Iizuka, Jin Song Shen, Xing Li Meng, Taisuke Mori, Akihiro Umezawa, Toya Ohashi and Yoshikatsu Eto
Mol Ther 9: S326-S326; doi:10.1016/j.ymthe.2004.06.766
859. A Skin-Restricted Conditionally Expressing Mouse Model of Pompe Disease for Assessment of Gene and Enzyme Replacement Therapies
Kerry O. Cresawn, Nina Raben, Paul H. Plotz, Christina Pacak, Adam Glick and Barry J. Byrne
Mol Ther 9: S326-S327; doi:10.1016/j.ymthe.2004.06.767
860. Long-Term Correction of Lysosomal Storage in CNS and Somatic Tissue in Adult MPS II Mice by Intravenous Administration of AAV
Joseph Muenzer, Jerillyn S. Jennings and Haiyan Fu
Mol Ther 9: S327-S327; doi:10.1016/j.ymthe.2004.06.848
861. Neonatal Gene Therapy with a Lentiviral Vector Results in Therapeutic Levels of |[alpha]|-Galactosidase A Correction in Fabry Mice
Makoto Yoshimitsu, Kesheng Tao, Xiaohu Fan, Lori West and Jeffrey A. Medin
Mol Ther 9: S327-S327; doi:10.1016/j.ymthe.2004.06.768
862. Improved Efficacy of Adenovirus-Mediated Gene Therapy for GSD-II Disease by Selective Depletion of Kupffer Cells
Shaoxi Liao, Ruth Everett, Fang Xu, Delila Serra, Nico Van Rooijen and Andrea Amalfitano
Mol Ther 9: S328-S328; doi:10.1016/j.ymthe.2004.06.769
863. Expression and Secretion of Human Glucocerebrosidase Mediated by Recombinant Lentivirus Vectors In Vitro and In Vivo
Eun Young Kim, Young Bin Hong, Zhennan Lai, Roscoe O. Brady and Sung-Chul Jung
Mol Ther 9: S328-S328; doi:10.1016/j.ymthe.2004.06.770
864. AAV-2-Mediated Expression of |[alpha]|-N-Acetyl-Glucosaminidase in Peripheral Tissues and the CNS in Mucopolysaccharidosis IIIB Mice by Combined Intravenous and Intracisternal Vector Delivery
Lu Kang, Jerillyn S. Jennings, Joseph Muenzer and Haiyan Fu
Mol Ther 9: S328-S329; doi:10.1016/j.ymthe.2004.06.771
865. An Ex Vivo Gene Therapy Approach for Metachromatic Leukodystrophy Using Neural Progenitor Cells
Ken Kawabata, Makoto Migita, Hideki Mochizuki, Yoshitaka Fukunaga and Takashi Shimada
Mol Ther 9: S329-S329; doi:10.1016/j.ymthe.2004.06.772
866. Modification of the expression vector for systemic gene therapy of MLD
Yukiko Takakusaki, Sanae Hisayasu, Atsushi Watanabe and Takashi Shimada
Mol Ther 9: S329-S329; doi:10.1016/j.ymthe.2004.06.773
867. Correction of Glycogen Storage Disease Type II by Intramuscular Administration of an Adeno-Associated Virus 6 (AAV2/6) Vector Containing a Muscle-Specific Promoter
Haoyue Zhang, Baodong Sun, Luis Franco, Andrew Bird, Ayn Schneider and Dwight D. Koeberl
Mol Ther 9: S329-S330; doi:10.1016/j.ymthe.2004.06.774
868. Enhancement of Gene Therapy Approaches for the Correction of Farber Disease
Shobha M. Ramsubir, Claudine Tardy, Stephane Carpentier, Thierry Levade and Jeffrey A. Medin
Mol Ther 9: S330-S330; doi:10.1016/j.ymthe.2004.06.775
869. Unique Potential of Gene Therapy for GSD-II Using Fully Deleted Adenovirus Based Vectors Expressing hGAA
Anne Kiang, Fang Xu, Shiao Xi Liao, Donna J. Palmer, Philip Ng and Andrea Amalfitano
Mol Ther 9: S330-S330; doi:10.1016/j.ymthe.2004.06.776
870. Gene Transfer in the Sandhoff Murine Model Using Lentiviral Vectors
Audrey Arfi, Christophe Bourgoin, Luisa Basso, Sandro Sonnino, Livia Poenaru and Catherine Caillaud
Mol Ther 9: S331-S331; doi:10.1016/j.ymthe.2004.06.777
871. Long-Term Expression of Sleeping Beauty Transposon in the Murine Model of Mucopolysaccharidosis (MPS) Type VII
Elena L. Aronovich, Jason B. Bell, Lalitha R. Belur, Joel L. Fransden, Roland Gunther, Brenda Koniar, David C. C. Erickson, R. Scott McIvor, Perry B. Hackett and Chester B. Whitley
Mol Ther 9: S331-S331; doi:10.1016/j.ymthe.2004.06.778
872. AAV 1 and 8 Have Higher Efficacy Than AAV 2 in Correction of Hyperbilirubinemia in the Gunn Rat, the Animal Model for the Metabolic Liver Dissorder Crigler-Najjar Syndrome
Piter J. Bosma, Berry de Jong, Norbert Looije, Cindy Kunne, Conny T. Bakker and Jurgen Seppen
Mol Ther 9: S331-S332; doi:10.1016/j.ymthe.2004.06.779
873. Low Level Hepatocyte Repopulation Corrects Hyperphenylalaninemia in Murine Phenylketonuria
Cary O. Harding, Kelly Hamman, Heather Clark, Eugenio Montini, Muhsen Al-Dhalimy, Markus Grompe and Milton Finegold
Mol Ther 9: S332-S332; doi:10.1016/j.ymthe.2004.06.780
874. Hepatocellular Morphology in the Pah enu2 Mouse Model of PKU Is Altered Following Portal Vein Administration of rAAV-mPAH-WPRE Vectors
Jeniffer E. Embury, Catherine E. Charron and Philip J. Laipis
Mol Ther 9: S332-S333; doi:10.1016/j.ymthe.2004.06.781
875. Ribozyme Approaches towards Down-Regulation of Pi|[ast]|Z Mutant Human A-1 Anti-Trypsin
Thomas J. Conlon, Stuart G. Beattie, Chris W. Snyder, Alfred S. Lewin and Terry R. Flotte
Mol Ther 9: S333-S333; doi:10.1016/j.ymthe.2004.06.782
876. Towards establishing a heterologous liver in rodents
Kazuo Ohashi, Takashi Yokoyama, Hiroyuki Kuge, Yoshiyuki Nakajima and Mark A. Kay
Mol Ther 9: S333-S334; doi:10.1016/j.ymthe.2004.06.847
877. Evidence for dominant-negative interference in the Pah enu2 mouse model of PKU
Catherine E. Charron, Alfred S. Lewin and Philip J. Laipis
Mol Ther 9: S334-S334; doi:10.1016/j.ymthe.2004.06.783
878. Correction of maternal phenylketonuria syndrome in the Pah enu2 Missense Mutant mouse by r-AAV mediated gene therapy
Philip J. Laipis, Catherine E. Charron, Jennifer E. Embury, O. P. Perera, Stacey L. Porvasnik, Carl R. Fields and Roberto T. Zori
Mol Ther 9: S334-S334; doi:10.1016/j.ymthe.2004.06.784
879. Morphologic and Immunohistochemical Evaluation of Dopaminergic Regions of Pah enu2 Mouse Brains Following Adminstration of rAAV-mPAH-WPRE Vector
Jennifer E. Embury, Catherine E. Charron and Philip J. Laipis
Mol Ther 9: S335-S335; doi:10.1016/j.ymthe.2004.06.785
880. Suppression of inflammation in a rat model of arthritis following intramuscular administration of AAV-TNFR:Fc vector pseudotyped with AAV type 1 capsid
Ziv Sandalon, Kurt Lustig and Haim Burstein
Mol Ther 9: S335-S335; doi:10.1016/j.ymthe.2004.06.786
881. Preclinical safety assessment of intra-articular administration of rAAV-humanTNFR:Fc in rats in support of a phase I arthritis trial
Laurie M. Tatalick, Linda D. Wilson, Tara L. Allen, Dana B. Martin and Pervin Anklesaria
Mol Ther 9: S335-S336; doi:10.1016/j.ymthe.2004.06.787
882. Adenovirus-Mediated Gene Transfer of Human Growth and Differentiation Factor-5 (GDF-5) into the Healing Rat Achilles Tendon
Haili Wang, Markus Rickert, Peter Wieloch, Helga Lorenz, Eric Steck and Wiltrud Richter
Mol Ther 9: S336-S336; doi:10.1016/j.ymthe.2004.06.788
883. Non viral gene therapy by electrotransfer of hTNF-|[alpha]| soluble receptor-I variants and its application to the treatment of experimental arthritis
Carole Bloquel, Natacha Bessis, Christophe Boissier, Daniel Scherman and Pascal Bigey
Mol Ther 9: S336-S336; doi:10.1016/j.ymthe.2004.06.789
884. Gene gun particle encoding preproenkephalin (PPE) cDNA produces analgesia against capsaicin Induced bladder pain in rats
Yao-Chi Chuang, Hong-Yo Kang, Po-Hui Chiang, Michael B. Chancellor and Naoki Yoshimura
Mol Ther 9: S336-S337; doi:10.1016/j.ymthe.2004.06.790
885. VEGF Enhances Bone Formation and Bone Healing Elicited by Transduced Muscle-Derived Stem Cells Expressing Human BMP2
Hairong Peng, Arvydas Usas, Brian Gearhart and Johnny Huard
Mol Ther 9: S337-S337; doi:10.1016/j.ymthe.2004.06.791
886. Determination of Osteoprogenitor-Specific Promoter Activity in Murine Mesenchymal Stem Cells by Recombinant Adeno-Associated Virus Transduction
Sanjay Kumar, Gandham Mahendra and Selvarangan Ponnazhagan
Mol Ther 9: S337-S337; doi:10.1016/j.ymthe.2004.06.792
887. Bone Formation by Ex Vivo Gene Therapy Using Lentiviral Vector Expressing BMP-2 under the Control of the MLV Promoter
Osamu Sugiyama, Dong Sung An, Seth Gamradt, Nancy Q. Liu, Irvin S. Y. Chen and Jay R. Lieberman
Mol Ther 9: S337-S338; doi:10.1016/j.ymthe.2004.06.793
888. A BMP2/7 Fusion Gene Enhances Osteoblastic Differentiation in Mesenchymal Cells
Wei Zhu, Oheneba Boachie-Adjei, Bernard Rawlins, Ronald G. Crystal and Chisa Hidaka
Mol Ther 9: S338-S338; doi:10.1016/j.ymthe.2004.06.794
889. Relationship between the amount of bone formation and protein expression in two rat stains using direct adenoviral vector injection and ex vivo method
Jin Zhong Li, Hongwei Li, El Noh, Lindsey Jacobson, An-Hsiang Liu, Dwight Saulle, Gerald R. Hankins and Gregory A. Helm
Mol Ther 9: S338-S339; doi:10.1016/j.ymthe.2004.06.795
890. Comparison of the osteogenic potential of AAVhBMP6 and ADhBMP6 between two rat strains
Jin Zhong Li, Hongwei Li, An-Hsiang Liu, Lindsey Jacobson, El Noh, Dwight Saulle, Gerald R. Hankins, John A. Chriorini and Gregory A. Helm
Mol Ther 9: S339-S339; doi:10.1016/j.ymthe.2004.06.796
891. Effect of the timing of direct adenoviral gene delivery on the healing of critical sized bone defects in rats
Oliver B. Betz, Marcus Egermann, Volker M. Betz, Ara Nazarian, Andre F. Steinert, Glyn D. Palmer, Mary L. Bouxsein, Mark S. Vrahas, Thomas A. Einhorn and Christopher H. Evans
Mol Ther 9: S339-S340; doi:10.1016/j.ymthe.2004.06.797
892. Enhanced survival of chondrocytes over expressing insulin-like growth factor I in equine cartilage repair
Laurie R. Goodrich, Chisa Hidaka, Lisa M. Strassheim, Paul D. Robins, Evans H. Chris and Alan J. Nixon
Mol Ther 9: S340-S340; doi:10.1016/j.ymthe.2004.06.798
893. Effect of hepatic insulin gene therapy on intrahepatic carbohydrate metabolism in vivo
Darin E. Olson, Adam G. Campbell and Peter M. Thule'
Mol Ther 9: S341-S341; doi:10.1016/j.ymthe.2004.06.799
894. Targeting adenovirus mediated gene transfer to chondrocytes in vitro
Michael P. Seiler, Margaretha Guenther, Skip Mercier, Donna Palmer, Phillip Ng, Charlott Brunmark, Michael A. Barry and Brendan H. Lee
Mol Ther 9: S341-S341; doi:10.1016/j.ymthe.2004.06.800
895. The differential effect of BMP4 on C2C12 and NIH/3T3 cells: Implications for gene therapy for bone and cartilage repair
Guangheng Li, Hairong Peng, Karin Corsi, Arvydas Usas and Johnny Huard
Mol Ther 9: S341-S342; doi:10.1016/j.ymthe.2004.06.801
896. Local direct injection of BMP2-modified fibroblasts induces ectopic bone formation in immunocompetent mice
Enrico Pola, Wanda Lattanzi, Giovanni Pecorini, Pierangelo Papaleo, Giuseppe Straface, Carlo A. Logroscino, Andrea Gambotto and Paul D. Robbins
Mol Ther 9: S342-S342; doi:10.1016/j.ymthe.2004.06.802
897. The development of standards for cell and gene therapy products: The activities of the United States pharmacopeia
Flavia Borellini, Sally S. Seaver, Ian F. DeVeau and Beth M. Hutchins
Mol Ther 9: S342-S342; doi:10.1016/j.ymthe.2004.06.803
898. Human hematopoietic repopulating stem and progenitor cells can be efficiently selected based on high aldehyde dehydrogenase activity
David A. Hess, Todd E. Meyerrose, Louisa Wirthlin, Phillip E. Herrbrich, Timothy P. Craft and Jan A. Nolta
Mol Ther 9: S342-S343; doi:10.1016/j.ymthe.2004.06.804
899. Stable gene expression under the control of the |[beta]|-Globin LCR in hematopoietic cells after transduction with integrating helper-dependent adeno-AAV vectors
Hongjie Wang, Dmitry Shayakhmetov, Qiliang Li, Thalia Papayannopoulou, George Stamatoyannopolous and Andr|[eacute]| Lieber
Mol Ther 9: S343-S343; doi:10.1016/j.ymthe.2004.06.805
900. Development of models for RPS19 deficient diamond-blackfan anemia using regulatable expression of siRNA against RPS19
Koichi Miyake, Johan Flygare, Thomas Kiefer, Johan Richter, Isao Hamaguchi, Maciej Wiznerowicz, Didier Trono and Stefan Karlsson
Mol Ther 9: S343-S344; doi:10.1016/j.ymthe.2004.06.806
901. Transactivation of fetal hemoglobin genes by engineered zinc-finger protein transcription factors for the treatment of sickle cell disease
Andreas Reik, Jeffrey D. Milner, Tom Ryan, Philip D. Gregory, Tim Townes and Casey C. Case
Mol Ther 9: S344-S344; doi:10.1016/j.ymthe.2004.06.807
902. A novel in vivo, lentivirus-based model of |[alpha]|-spectrin function
Sara Mootien, Nancy E. Siedel, David M. Bodine and Patrick G. Gallagher
Mol Ther 9: S344-S344; doi:10.1016/j.ymthe.2004.06.808
903. Group I Ribozymes and SMaRT|[trade]| as Trans-Splicing RNA Repair Therapies for |[beta]|-Globin Mutations
Monique N. Kierlin, Jonghoe Byun, Ning Lan, Meredith Long and Bruce Sullenger
Mol Ther 9: S345-S345; doi:10.1016/j.ymthe.2004.06.809
904. Lentiviral transduction of Wiskott-Aldrich Syndrome (WAS) deficient, t-cells leads to long-term and progressive WAS protein expression and functional reconstitution
Carol H. Miao, Qili Zhu, Ling Zhou, Stephanie Humblet-Baron, Datien Lin, Donald B. Kohn, Fabio Candotti, Hans D. Ochs and David J. Rawlings
Mol Ther 9: S345-S345; doi:10.1016/j.ymthe.2004.06.810
905. The endogenous WASp promoter fragments in SIN lentiviral vectors drive expression preferentially in T cells
Xiangyang Jin, Denise A. Carbonaro, Dinithi Senadherra, Denise Petersen, Sau-Ping Kwan and Donald B. Kohn
Mol Ther 9: S345-S346; doi:10.1016/j.ymthe.2004.06.811
906. Successful functional correction of T cells from Wiskott-Aldrich syndrome patients with lentiviral vectors
Lo|[iuml]|c Dupr|[eacute]|, Francesco Marangoni, Antonia Follenzi, Sara Trifari, Silvana Martino, Shigeru Tsuchiya, Claudio Bordignon, Luigi Naldini, Alessandro Aiuti and Maria Grazia Roncarolo
Mol Ther 9: S346-S346; doi:10.1016/j.ymthe.2004.06.812
907. T lymphocyte-directed gene therapy for IL-12R|[beta]|1 deficiency
Marita Bosticardo, Claire Fieschi, Francesco Novelli, Jean-Laurent Casanova and Fabio Candotti
Mol Ther 9: S346-S346; doi:10.1016/j.ymthe.2004.06.813
908. Selective enrichment of transduced cells for gene therapy of an inherited immune deficiency, chronic granulomatous disease
Olga Ujhelly, Judit Cervenak, Csilla Laczka Ozvegy, Manuel Grez, Balazs Sarkadi and Katalin Nemet
Mol Ther 9: S347-S347; doi:10.1016/j.ymthe.2004.06.814
909. In vivo repopulating ability of genetically-corrected BM cells from Fanconi's aneamia A patients
Odile Y. Cohen-Haguenauer, Christian Auclair and Michel Marty
Mol Ther 9: S347-S347; doi:10.1016/j.ymthe.2004.06.815
910. Hematopoietic cell differentiation of common marmoset (Callithrix jacchus) embryonic stem cells and their genetic manipulation using the third generation lentiviral vector
Ryo Kurita, Erika Sasaki, Takashi Hiroyama, Yukoh Nakazaki, Kiyoko Izawa, Hajime Ishii, Yoshikuni Tanioka, Kisaburo Hanazawa, Makoto Osonoi, Takao Hashiguchi, Yuan-Son Bai, Yasushi Soda, Xiao jin Li, Sumiko Watanabe, Shigetaka Asano and Kenzaburo Tani
Mol Ther 9: S347-S348; doi:10.1016/j.ymthe.2004.06.816
911. MHC class I and II mismatched marrow stromal cells from C57Bl/6 mice are immune rejected by recipient Balb/c mice
Nicoletta Eliopoulos, John Stagg, Laurence Lejeune and Jacques Galipeau
Mol Ther 9: S348-S348; doi:10.1016/j.ymthe.2004.06.817
912. Strategies using retroviral coexpression of indoleamine 2,3 dioxygenase and fas ligand for allogeneic bone marrow transplantation
Bagirath Gangadharan, Lucienne Ide, David Holtzclaw, David Archer and H. Trent Spencer
Mol Ther 9: S348-S349; doi:10.1016/j.ymthe.2004.06.818
913. MGMT (P140K) allows for safe, efficient, and sustained in vivo selection and chemoprotection in a large animal model
Brian C. Beard, Tobias Neff, Laura J. Peterson, Bobbie Thomasson, Jesse Thompson and Hans-Peter Kiem
Mol Ther 9: S349-S349; doi:10.1016/j.ymthe.2004.06.819
914. Mutant MGMT Lentivirus Co-Transduction ith a Marker Lentivirus Efficiently Enriches for Dual-Vector Expressing Cells In Vivo
Justin C. Roth, Mourad Ismail, Giuliana Ferrari and Stanton L. Gerson
Mol Ther 9: S349-S349; doi:10.1016/j.ymthe.2004.06.820
915. Insertional analyses in rhesus monkey blood cells after non-myeloablative hematopoietic stem cell marking with a therapeutic onco-retroviral vector for x-linked chronic granulomatous disease
Martin F. Ryser, Sebastian Brenner, Narda Whiting-Theobald, Romy Lehmann, Uimook Choi, Gilda F. Linton, Elizabeth Kang, Andrew G. Rudikoff, Ann M. Farese, Thomas J. MacVittie, Mitchell E. Horwitz and Harry L. Malech
Mol Ther 9: S350-S350; doi:10.1016/j.ymthe.2004.06.821
916. Systematic analysis of retroviral vector integrations in human marrow-repopulating cells by the aid of a data warehouse
Stephanie Laufs, K. Zsuzsanna Nagy, Guillermo Guenechea, Frank A. Giordano, Africa Gonzalez-Murillo, Kurt Fellenberg, Agnes Hotz-Wagenblatt, Juan A. Bueren, W. Jens Zeller and Stefan Fruehauf
Mol Ther 9: S350-S350; doi:10.1016/j.ymthe.2004.06.822
917. Long-term transgene expression following gene delivery directly to the bone marrow using recombinant SV40-derived vectors
Bianling Liu, Judy Daviau and David S. Strayer
Mol Ther 9: S350-S351; doi:10.1016/j.ymthe.2004.06.823
918. Autologous canine bone marrow stromal cells retrovirally engineered with the canine EPO gene and implanted in vivo in a collagen matrix produce and release systemically functional EPO over a prolonged period
Francois Fontaine, Marilyn Dunn, Juan Hernandez, Nicoletta Eliopoulos, Helene Boucher, James N. MacLeod, Jacques Galipeau and Daniel Martineau
Mol Ther 9: S351-S351; doi:10.1016/j.ymthe.2004.06.824
919. Gene therapy for platelet disorders: targeting transgene expression in canine platelets
Lily M. Du and David A. Wilcox
Mol Ther 9: S351-S352; doi:10.1016/j.ymthe.2004.06.825
920. Assessing the risk from transfer of an integrin |[beta]|3 gene that encodes a naturally occurring polymorphism associated with acute coronary thrombosis
Juan Fang, Bryon D. Johnson and David A. Wilcox
Mol Ther 9: S352-S352; doi:10.1016/j.ymthe.2004.06.826
921. Biopump: a novel approach to gene-mediated protein production and delivery with application for erythropoietin treatment of anemia
Einat Brill-Almon, Andrew Pearlman, Baruch Stern, Noga Langer, Daniel Afik, Menachem Shavit, Yitzhak Lippin, Amos Panet, Eithan Galun, Eduardo Mitrani and Noam Shani
Mol Ther 9: S352-S353; doi:10.1016/j.ymthe.2004.06.827
922. Deriving tissues from embryonic stem cells
Gordon Keller, Atsushi Kubo, Hans Joerg Fehling and Valerie Kouskoff
Mol Ther 9: S353-S353; doi:10.1016/j.ymthe.2004.06.828
923. Modeling hematopoietic transplantation with ES cells
George Q. Daley
Mol Ther 9: S353-S353; doi:10.1016/j.ymthe.2004.06.829
924. Gene Therapy with IGF-1 Growth Factor for Heart Failure
Armelle Serose, Andre Salmon, Bernard Prudhon, Marie Agnes Doyennette, Marc Y. Fiszman and Yves Y. Fromes
Mol Ther 9: S353-S354; doi:10.1016/j.ymthe.2004.06.850
925. Electroporation Mediated Gene Transfer of Human Interleukin-10 to Skeletal Muscle Reduces Acute Rejection in Rat Cardiac Allografts
Reza Tavakoli, Amiq Gazdhar, Jaroslaw Pierog, Anna Bagdannova, Mathias Gugger, Steven Hyde, Michele Genoni and Ralph Schmid
Mol Ther 9: S354-S354; doi:10.1016/j.ymthe.2004.06.851
926. Bcl-xL Gene Transfer Improves Graft Survival and Prolongs the Cold-Preservation Time in the Heart Transplantation
Jinghua Huang, Yoshinori Ito, Takeshi Uzuka, Masayoshi Kobune, Yukiko Honma, Kiminori Nakamura, Hiroaki Uchida, Hironari Dehari and Hirofumi Hamada
Mol Ther 9: S354-S355; doi:10.1016/j.ymthe.2004.06.852
927. Cell Therapy To Restore Perfusion and Cardiac Function in Infarcted Heart Is Improved by EPAS1 Gene Transfer
Louis-Georges Guy, Yoshihisa Morimoto, Sandra Iacampo, Anouk S. Fortin, Bryce H. Davis, Guy Leclerc and Doris A. Taylor
Mol Ther 9: S355-S355; doi:10.1016/j.ymthe.2004.06.853
928. Hypoxia-Regulated Heme Oxygenase-1 Vector Confers Cardioprotection Against Ischemic Damage
Yao Liang Tang, Yi Tang, Y. Clare Zhang, Keping Qian and M. Ian Phillips
Mol Ther 9: S355-S355; doi:10.1016/j.ymthe.2004.06.854
929. Target Adult Stem Cells to Ischemic Hearts by Regulated Stromal Cell-Derived Factor 1 Gene Transfer
Yao Liang Tang, Keping Qian, Leping Shen, M. Ian Phillips and Y. Clare Zhang
Mol Ther 9: S355-S356; doi:10.1016/j.ymthe.2004.06.855
930. Muscle Stem Cells Deliver Dystrophin and Adopt a Cardiac Phenotype through Both Differentiation and Fusion in the Dystrophic (mdx) Heart
Thomas R. Payne, Hideki Oshima, Tetsuro Sakai, Yiqun Ling, Burhan Gharabeih, James H. Cummins and Johnny Huard
Mol Ther 9: S356-S356; doi:10.1016/j.ymthe.2004.06.856
931. Enhanced Cardiac Muscle Contractility Achieved by Engineered Zinc Finger Transcriptional Repressors of Phospholamban
H. Steven Zhang, Lei Zhang, Yuxin Liang, Reed Hickey, Dmitry Guschin, Simon Chandler, Mike Kunis, Linda Hinh, Dengfeng Xia, Xiaohong Zhong, S. Kaye Spratt, J. Tyler Martin, Casey C. Case, Frank J. Giordano, Philip D. Gregory and Edward J. Rebar
Mol Ther 9: S356-S356; doi:10.1016/j.ymthe.2004.06.857
932. SV40 Pseudovirions Are Efficient and Safe Myocardial Gene Therapy Vectors
Ronen Beeri, Thea Pugatsch, Suzane Abedat, Mahmud Abdel Latif and Ariella Oppenheim
Mol Ther 9: S356-S357; doi:10.1016/j.ymthe.2004.06.858
933. Sendai Virus Vector Can Efficiently Introduce Transgene into Cardiomyocytes In Vitro and In Vivo
Yukiko Honma, Yoshinori Ito, Hironari Dehari, Masayoshi Kobune, Jinghua Huang, Kiminori Nakamura, Takeshi Kobayashi, Takeshi Uzuka, Sachie Hirai, Hiroaki Uchida, Makoto Inoue, Mamoru Hasegawa, Masayuki Morikawa, Noritsugu Tohse, Tomio Abe and Hirofumi Hamada
Mol Ther 9: S357-S357; doi:10.1016/j.ymthe.2004.06.859
934. Comparing Two Modalities of Myocardial Gene Delivery: Percutaneous Retrograde Coronary Venous Delivery and Intramyocardial Injection
Eyas Al-Shaykh Youssef, Ping Zhang, Pamela Rogers, Patrice Tremble, Joe Rokovich, Brian Johnstone, Keith L. March and Dongming Hou
Mol Ther 9: S357-S358; doi:10.1016/j.ymthe.2004.06.860
935. Magnetofection and Ultrasound To Increase |[ldquo]|Naked|[rdquo]| DNA Delivery to the Myocardium
Uta Griesenbach, Philip Dean, Nicola Marshall, Hai-Dong Liang, Stefania Xenariou, Duncan M. Geddes, Martin J. Blomley, Christian Plank and Eric W. F. W. Alton
Mol Ther 9: S358-S358; doi:10.1016/j.ymthe.2004.06.861
936. Phage-Selected Motifs Internalize Via Multiple Endocytic Pathways and Facilitate Gene Delivery
Zhengrong Hao, Yan Huang, Dinggang Liu, Jun Yu, Bill Sessa and Frank J. Giordano
Mol Ther 9: S358-S359; doi:10.1016/j.ymthe.2004.06.862
937. siRNA Inhibition of MMP9 Expression Inhibits TGF|[beta]|1-Induced Calcification of Aortic Valve Interstitial Cells
Jocelyn N. Clark, Elizabeth Palmatory, Robin Brittin, Navneet R. Narula, Joe Gorman, Robert C. Gorman and Robert J. Levy
Mol Ther 9: S359-S359; doi:10.1016/j.ymthe.2004.06.863
938. Myocardial Administration of Adenoviral Vector Encoding VEGF Induces Severe Pleural and Pericardial Effusion in Rat
Yoshinori Ito, Masayoshi Kobune, Takeshi Uzuka, Jinghua Huang, Yukiko Honma, Hironari Dehari, Hikaru Ueno and Hirofumi Hamada
Mol Ther 9: S359-S359; doi:10.1016/j.ymthe.2004.06.864
939. Adenoviral-Mediated Neuronal-Specific Overexpression of the Angiotensin AT2 Receptor
Hongwei Li, Yongxin Gao, Mohan K. Raizada and Colin Sumners
Mol Ther 9: S360-S360; doi:10.1016/j.ymthe.2004.06.866
940. Ribozyme Oligonucleotides Against TGF-|[beta]| Transferred by Ultrasound Inhibited the Progression of Diseases in Anti-Thy1 Model
Naruya Tomita, Keita Yamasaki, Kei Yamamoto, Hiromi Koike, Yasuo Kunugiza, Toshio Ogihara and Ryuichi Morishita
Mol Ther 9: S360-S360; doi:10.1016/j.ymthe.2004.06.867
941. Development of Cell Penetration Domain and Cell Killing Domain Genes for Treatment of Cancer
Sean M. Sullivan, Harm J. Knot, Ron Mandel, J. P. Jarajapu and Jacqueline Baltunis
Mol Ther 9: S360-S360; doi:10.1016/j.ymthe.2004.06.884
942. Combinatorial Treatment with Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Gene and a Chemotherapeutic Agent Suppressed Hepatic Metastasis of Colon Carcinoma
Michiaki Ishii, Masaki Iwai, Yoshinori Harada, Jiro Imanishi, Osam Mazda and Takeshi Okanoue
Mol Ther 9: S361-S361; doi:10.1016/j.ymthe.2004.06.885
943. Loss of Neoplastic Phenotype by Specific Inhibition of RET Oncogene Signalling in a Transgenic Model of Primary Medullary Thyroid Carcinoma
Matthias Drosten, Gero Hilken, Florian Rodicker, Miriam Bockmann, Carmen C. Theseling, Nikica Mise, Aaron N. Cranston, Andreja Frilling, Bruce A. Ponder and Brigitte M. Putzer
Mol Ther 9: S361-S361; doi:10.1016/j.ymthe.2004.06.886
944. The Histone Deacetylase Inhibitor Depsipeptide (FR901228) Enhances the Cytotoxic Activity of Ad5-TRAIL Against Human Prostate Tumor Cells
Thomas S. Griffith, Jill Moore and Rebecca Van Oosten
Mol Ther 9: S361-S362; doi:10.1016/j.ymthe.2004.06.887
945. E1B-Mutant Replication Competent Adenovirus Combined with Chemotherapeutic Agents Shows Increased Anti-Tumor Effect
A-Rum Yoon, Pyung-Hwan Kim, Joo-Hyuk Sohn, Chae-Ok Yun and Joo-Hang Kim
Mol Ther 9: S362-S362; doi:10.1016/j.ymthe.2004.06.888
946. Combined E1B-Mutant Adenovirus and Radiotherapy Generates Synergistic Anti-Tumor Effects
Jaesung Kim, Jung-Hee Choi, Jing-Hua Huang, Pyung Hwan Kim, Beom-Seok Suh, Jin-Sil Seong and Chae-Ok Yun
Mol Ther 9: S362-S362; doi:10.1016/j.ymthe.2004.06.889
947. RNAi-Mediated Bcl-XL Depletion Sensitizes Pancreatic Cancer Cells to TNF|[alpha]| Induced Apoptosis
Jirong Bai and Mark P. Callery
Mol Ther 9: S363-S363; doi:10.1016/j.ymthe.2004.06.890
948. Regression of Established Melanoma Tumors through Intratumoral Delivery of HIV-1 Vpr Using In Vivo Electroporation
Andrea N. McCray, Chuanhai Cao, Karuppiah Muthumani, David B. Weiner, Kenneth Ugen and Richard Heller
Mol Ther 9: S363-S363; doi:10.1016/j.ymthe.2004.06.891
949. Intratumoral Adenovirus-Mediated Interferon alpha Gene Transfer Induces Regional Direct Cytotoxicity and Possible Systemic Immunity Against Pancreatic Cancer
Kazunori Aoki, Masaki Ohashi, Yoshiaki Miura, Kimiko Yoshida, Shumpei Ohnami, Yukio Kitade and Teruhiko Yoshida
Mol Ther 9: S363-S363; doi:10.1016/j.ymthe.2004.06.892
950. FasL- Over-Expressing T Lymphocytes as Effector Cells in Anti-Prostate Cancer Gene Therapy
Julie C. Bielawski, Daniel H. Fowler and Jeffrey A. Medin
Mol Ther 9: S364-S364; doi:10.1016/j.ymthe.2004.06.893
951. Antitumor Activity of AAV-2 Vector Encoding Modified TRAIL Gene
Jinsang Yoo, Seeyoung Choi, Kyung-Sun Hwang, Won-Kyung Cho, Cho-Rok Jung and Dong-Soo Im
Mol Ther 9: S364-S364; doi:10.1016/j.ymthe.2004.06.894
952. Delivery of Tissue Inhibitor of Metalloproteinase 3 Inhibits Growth of Lung Cancer Tumours In Vivo
Katherine M. Finan, Greg Hodge, Ann M. Reynolds, Sandra J. Hodge, Mark D. Holmes, Andrew H. Baker and Paul N. Reynolds
Mol Ther 9: S364-S364; doi:10.1016/j.ymthe.2004.06.895
953. STAT5 Is Phosphorylated in Malignant Melanoma Leading to Proliferation Via Activation of ERK: Potential for Anti-Tumor Therapy
Alireza Mirmohammadsadegh, Walter Bardenheuer, Annett Baer, Sandeep Nambiar and Ulrich R. Hengge
Mol Ther 9: S365-S365; doi:10.1016/j.ymthe.2004.06.896
954. Ectopic Production of MDA-7/IL-24 Inhibits Invasion and Migration of Human Lung Cancer Cells
Isao Ito, Began Gopalan, Yuji Saito, Abner M. Mhashilkar, Sunil Chada and Rajagopal Ramesh
Mol Ther 9: S365-S365; doi:10.1016/j.ymthe.2004.06.897
955. Bystander Activity of Ad-mda7: MDA-7 Protein Kills Melanoma Cells Via a Receptor-Dependent but STAT3-Independent Mechanism
Sunil Chada, Abner Mhashilkar, Rajagopal Ramesh, John B. Mumm, Dora Bocangel, Elizabeth A. Grimm and Suhendan Ekmekcioglu
Mol Ther 9: S365-S365; doi:10.1016/j.ymthe.2004.06.898
956. Suppression of Tumor Metastasis by Adenoviral-Mediated MRP-1/CD9 Expression
Yi Lu, Jun Zhang, Bogdan Ceacareanu, Aviv Hassid and Lisa K. Jennings
Mol Ther 9: S365-S366; doi:10.1016/j.ymthe.2004.06.899
957. bcl-xL Antisense Oligonucleotides as an Enhancer of the Cytotoxic Effects of Cisplatin, Mitomycin C and Paclitaxel in the Treatment of Bladder Cancer
Axel Schaaf, Sreedhar Sagi, Sigrun Langbein, Lutz Trojan, Peter Alken and Maurice S. Michel
Mol Ther 9: S366-S366; doi:10.1016/j.ymthe.2004.06.900
958. Rapid Blockade of Telomerase Activity and Tumor Cell Growth by Ribbon Antisense Oligodeoxynucleotides to hTR
Jong-Gu Park and Arun Bajpai
Mol Ther 9: S366-S366; doi:10.1016/j.ymthe.2004.06.901
959. bcl-2 Antisense Oligonucleotides Enhance the Cytotoxic Effects of Mitomycin C in the Treatment of Bladder Cancer
Axel Schaaf, Sreedhar Sagi, Sigrun Langbein, Lutz Trojan, Peter Alken and Maurice S. Michel
Mol Ther 9: S366-S367; doi:10.1016/j.ymthe.2004.06.902
960. Regulation of Cyclooxygenase-2 and Vascular Endothelial Growth Factor Promoter Based Conditionally Replicating Adenoviruses for Treatment of Cervical Cancer
Anna Kanerva, Mari Raki, Gerd J. Bauerschmitz, Koichi Takayama, Masato Yamamoto, Renee A. Desmond, David T. Curiel and Akseli Hemminki
Mol Ther 9: S367-S367; doi:10.1016/j.ymthe.2004.06.903
961. E1B-55 kD-Deleted Adenovirus Driven by Murine Oct-3/4 Promoter for Bladder Cancer Therapy
Chun-Fu Chang, Ai-Li Shiau, Gia-Shing Shieh and Chao-Liang Wu
Mol Ther 9: S367-S367; doi:10.1016/j.ymthe.2004.06.904
962. Hypoxia- and Radiation-Activated Cre/loxP Molecular Switch Vectors for Gene Therapy of Solid Tumors
Olga Greco, Brian Marples, Michael C. Joiner, George D. Wilson and Simon D. Scott
Mol Ther 9: S368-S368; doi:10.1016/j.ymthe.2004.06.905
963. Development and Testing of Anti-Cancer Sleeping Beauty Transposons for Localized Tumors and Use in Metastasis Suppression
John R. Ohlfest, Scott Perkinson, Paul Lobitz, Diane Hasz, Joel Frandsen, R. Scott McIvor and David A. Largaespada
Mol Ther 9: S368-S368; doi:10.1016/j.ymthe.2004.06.906
964. Infectivity Enhanced, hTERT Promoter-Based Conditionally Replicative Adenoviruses Are Useful for the Treatment of Small Cell Lung Cancer
Koichi Takayama, Junji Uchino, Akiko Harada, Yosuke Kawakami, David T. Curiel and Yoichi Nakanishi
Mol Ther 9: S368-S369; doi:10.1016/j.ymthe.2004.06.907
965. A Novel Approach for Gene Transduction with Adenovirus/Fibrin Glue System
Minori Sakurai, Tkeyuki Misawa, Hiroaki Shiba, Yohji Yamazaki and Katuhiko Yanaga
Mol Ther 9: S369-S369; doi:10.1016/j.ymthe.2004.06.908
966. Synergy between Angiostatin-Endostatin and Tie-2: A Novel Anti-Angiogenic Gene Therapy for Prostate Cancer
Sudhanshu P. Raikwar, Chinghai Kao and Thomas A. Gardner
Mol Ther 9: S369-S369; doi:10.1016/j.ymthe.2004.06.909
967. Angiotensinogen Inhibits Growth and Angiogenesis of Human Mammary Carcinoma and Prevents Pulmonary Metastasis of Murine Melanoma Cancer
C|[eacute]|line Bouquet, Noel Lamande, Jean-Marie Gasc, Franck Griscelli, Paule Opolon, Elisabeth Connault, Michel Perricaudet and Pierre Corvol
Mol Ther 9: S370-S370; doi:10.1016/j.ymthe.2004.06.910
968. A Dual-Action Armed Replicating Adenovirus for the Treatment of Bone Metastases of Breast Cancer
James J. Cody, Gray R. Lyons and Joanne T. Douglas
Mol Ther 9: S370-S370; doi:10.1016/j.ymthe.2004.06.911
969. Transcription Controlled Gene Therapy Against Tumor Angiogenesis
Shoshana Greenberger, Aviv Shaish, Eyal Breitbart, Israel Hodish, Livnat Bangio, Niva Yaakov, Iris Goldberg, Iris Barshack, David Wallach, Tanya Goncharov and Dror Harats
Mol Ther 9: S370-S371; doi:10.1016/j.ymthe.2004.06.912
970. A Fiber Modified SLPI Promoter Based Conditionally Replicating Adenovirus for Treatment of Ovarian Cancer
Daniel T. Rein, Martina Breidenbach, Minghui Wang, Tyler O. Kirby, Gene P. Siegal, Gerd J. Bauerschmitz, Peter Dall, Dirk M. Nettelbeck, Akseli Hemminki, Ronald D. Alvarez and David T. Curiel
Mol Ther 9: S371-S371; doi:10.1016/j.ymthe.2004.06.913
971. New Generation Conditionally Replicative Adenovirus for Hormone-Refractory Prostate Cancer
Tatyana Gavrikova, Julia Davydova, Long P. Le, Hidetaka A. Ono, Pedro J. Ramirez, Victor Krasnykh, David T. Curiel and Masato Yamamoto
Mol Ther 9: S371-S372; doi:10.1016/j.ymthe.2004.06.914
972. Gene-Modified Human Glioma Cells Producing Soluble Human Plasminogen Kringle 5 Peptide Suppress Brain Tumor Progression
Sabrina R. Perri, Josephine Nalbantoglu, Borhane Annabi, Zafiro Koty, Richard B|[eacute]|liveau and Jacques Galipeau
Mol Ther 9: S372-S372; doi:10.1016/j.ymthe.2004.06.915
973. Efficient Transduction of Bone Marrow-Derived Mesenchymal Stem Cells for Cancer Gene Therapy Using a Tropism-Modified Adeno-Associated Virus (AAV) Vector
Brett M. Hall, Amy E. Henning and Jeffrey S. Bartlett
Mol Ther 9: S372-S373; doi:10.1016/j.ymthe.2004.06.916
974. Adeno-Associated Viral (AAV)-Mediated Gene Transfer of Soluble Vascular Endothelial Growth Factor Receptor 3 (sVEGFR3) Inhibits Development of Lymph Node Metastases
Jian-Min Lin, Alshad S. Lalani, Thomas Harding, Weiwei Wu, Bo Luan, Satya Yendluri, Melinda J. VanRoey, Yulong He, Kari Alitalo and Karin Jooss
Mol Ther 9: S373-S373; doi:10.1016/j.ymthe.2004.06.917
975. TSTA Mediated Multi-Modality Gene-Expression Imaging in Hormone Refractory Prostate Cancer
Makoto Sato, Mai Johnson, Liqun Zhang, Sanjiv S. Gambhir, Michael Carey and Lily Wu
Mol Ther 9: S373-S373; doi:10.1016/j.ymthe.2004.06.948
976. Decreased Tumorigenic Potential of EphA2-Overexpressing Breast Cancer Cells Following Treatment with Adenoviral Vectors That Express EphrinA1
Loren W. Noblitt, Dinesh S. Bangari, Shruti Shukla, Deborah W. Knapp, Sulma Mohammed, Michael S. Kinch and Suresh K. Mittal
Mol Ther 9: S374-S374; doi:10.1016/j.ymthe.2004.06.949
977. Selective Transduction of Malignant Glioma by Lentiviral Vectors Pseudotyped with LCMV Glycoproteins
Hrvoje Miletic, Yvonne Fischer, Harald Neumann, Volkmar Hans, Tsanan Giroglou, Martina Deckert and Dorothee von Laer
Mol Ther 9: S374-S374; doi:10.1016/j.ymthe.2004.06.950
978. Optimization of the Tet-on System To Regulate Interleukin 12 Expression in the Liver for the Treatment of Hepatic Tumors
Maider Zabala, Lin Wang, Ruben Hernandez-Alcoceba, Wolfgang Hillen, Cheng Qian, Jesus Prieto and Maria-Gabriela Kramer
Mol Ther 9: S374-S374; doi:10.1016/j.ymthe.2004.06.951
979. The Gene Expression and Function of Adenoviral E3-Genes in Murine Tumour Cell Lines
Richard J. Hill, Gunnel K. Hallden, Yaohe Wang, Jennelle Francis, Catherine Simpson, David H. Kirn and Nicholas R. Lemoine
Mol Ther 9: S374-S375; doi:10.1016/j.ymthe.2004.06.952
980. Evaluation of the Tumor Specificity of a Conditionally Replicative Adenovirus Controlled by a Modified Human Core Telomerase Promoter
Sergia Bortolanza, Ruben Hernandez-Alcoceba, Gabriela Kramer, Jesus Prieto and Cheng Qian
Mol Ther 9: S375-S375; doi:10.1016/j.ymthe.2004.06.953
981. Gene Therapy Clinical Trials Worldwide 1989-2003: An Overview
Michael L. Edelstein, Mohammad R. Abedi, Jo Wixon and Richard M. Edelstein
Mol Ther 9: S375-S376; doi:10.1016/j.ymthe.2004.06.954
982. Improved transduction of primary murine hepatocytes by recombinant adeno-associated virus 2 vectors in vivo
Li Zhong, Weiming Li, Zuocheng Yang, Linyuan Chen, Yanjun Li, Keyun Qing, Kirsten A. Weigel-Kelley, Mervin C. Yoder, Weinian Shou and Arun Srivastava
Mol Ther 9: S376-S376; doi:10.1016/j.ymthe.2004.06.920
983. Human Derived Dual Reporter/Suicide Gene System for Simultaneous Pet Imaging of Independent Molecular-Biological Processes In Vivo
Vilia Tourkova, Malgorzata Dabrovska, Michael Doubrovin, Inna Serganova, Jelena Vider, Tatiana Beresten, Shangive Cai, Ronald Finn, Juri Gelovani Tjuvajev and Vladimir Ponomarev
Mol Ther 9: S376-S377; doi:10.1016/j.ymthe.2004.06.921
984. Fetal Administration of Lentiviral Vectors and the Potential for Germ Cell Transduction in Rhesus Monkeys (Macaca mulatta)
Chang I. Lee, Daniel F. Jimenez, Donald B. Kohn and Alice F. Tarantal
Mol Ther 9: S377-S377; doi:10.1016/j.ymthe.2004.06.922
985. Transposition of the Agouti Transgene by Sleeping Beauty Transposon Is Not Associated with Significant Changes in DNA Methylation in the Mouse Genome
C.-W. Park, D. Largaspada, B. T. Kren and C. J. Steer
Mol Ther 9: S377-S377; doi:10.1016/j.ymthe.2004.06.923
986. Efficient Gene Delivery to Human and Rodent Islets with Double Stranded (ds)-AAV2-Based Vectors
Khaja K. Rehman, Zhong Wang, Rita Bottino, A. N. Balamurugan, Juan Li, Xiao Xiao, Massimo Trucco and Paul D. Robbins
Mol Ther 9: S378-S378; doi:10.1016/j.ymthe.2004.06.924
987. Highly Efficient Regulation of Gene Expression by Tetracycline in a Novel Replication-Defective Herpes Simplex Viral Vector
Feng Yao, Chris Theopold and Daniela Hoeller
Mol Ther 9: S378-S378; doi:10.1016/j.ymthe.2004.06.925
988. Effect of Lentiviral Promoter and Fetal Route of Administration on Transgene Biodistribution and Expression in Rhesus Monkeys (Macaca mulatta)
Daniel F. Jimenez, Chang I. Lee, Cristin E. O'Shea, Donald B. Kohn and Alice F. Tarantal
Mol Ther 9: S378-S378; doi:10.1016/j.ymthe.2004.06.926
989. IAI.3B Promoter Is Ovarian Cancer Specific
Katsuyuki Hamada
Mol Ther 9: S379-S379; doi:10.1016/j.ymthe.2004.06.927
990. Transduction of Pancreatic Islets with Pseudotyped Adeno-Associated Virus: Effect of Viral Capsid
Nan Zhang, Nathalie Clement, Haojiang Zhang, Dongmei Chen, Shuang Fu, Michael Linden and Jonathan S. Bromberg
Mol Ther 9: S379-S379; doi:10.1016/j.ymthe.2004.06.928
991. Construction of a Novel Human Artificial Chromosome and Its Use for Gene Delivery
Motonobu Katoh, Fumiaki Ayabe, Satoko Norikane, Hidetoshi Hoshiya, Xianying Ren, Tetsuji Suda, Chiga Okita and Mitsuo Oshimura
Mol Ther 9: S379-S379; doi:10.1016/j.ymthe.2004.06.929
992. Lentiviral and Retroviral Vectors for Transcriptionally Targeted Expression of Human Beta-Globin
Annarita Miccio, Giulia Facchini, Francesco Lotti, Claudia Rossi and Giuliana Ferrari
Mol Ther 9: S380-S380; doi:10.1016/j.ymthe.2004.06.930
993. Activation of Gene Expression from Silenced Adenovector Genomes
Duncan McVey, Chi Hsu, Lisa Wei, C. Richter King and Douglas E. Brough
Mol Ther 9: S380-S380; doi:10.1016/j.ymthe.2004.06.931
994. Gene Knockdown in Mice by Using Lentiviral Vectors Expressing Small Interfering RNA
Oded Singer, Masahito Ikawa, Nien Hoong, Greg Campbell and Inder M. Verma
Mol Ther 9: S380-S381; doi:10.1016/j.ymthe.2004.06.932
995. Inducible Gene Expression by Use of an HET-Amplicon Vector
Alexandra Winkeler, Miguel Sena-Esteves, Norbert Galldiks, Lisa Li, Markus Klein, Parisa Monfared, Maria A. Rueger, Christof Knoess, Klaus Wienhard, Benedikt Rueckriem, Wolf D. Heiss and Andreas H. Jacobs
Mol Ther 9: S381-S381; doi:10.1016/j.ymthe.2004.06.933
996. Application of a Novel Human Artificial Chromosome (HAC) Vector to Gene Therapy Aimed at Erythropoietin (EPO) Replacement
Minoru Kakeda, Masaharu Hiratsuka, Keiko Nagata, Masayo Takahashi, Fumiaki Ayabe, Motonobu Katoh, Mitsuo Oshimura and Kazuma Tomizuka
Mol Ther 9: S381-S381; doi:10.1016/j.ymthe.2004.06.934
997. Specific Expression of Transgenes in Insulin-Secreting Islet Cells by Lentiviral Vectors
Andreas Hofmann, Dagmar Kress, Barbara Kessler, Eckhard Wolf and Alexander Pfeifer
Mol Ther 9: S382-S382; doi:10.1016/j.ymthe.2004.06.935
998. Evaluation of Promoter Elements for Specific Expression in Human Airway Epithelia Using a Self-Inactivating (SIN) Equine Lentivector
Angela M. Giddings, Lawrence Ostrowski and John C. Olsen
Mol Ther 9: S382-S382; doi:10.1016/j.ymthe.2004.06.936
999. Development of Orthogonal Multiplex Gene-Switch Systems Based on Engineered Ecdysone Receptors and Inducing Ligands Selected from a Single Chemotype
Jennifer L. Friz, Beth Vertin, Christine S. Thompson, Subba R. Palli, Mohan Kuman, Orestes Chortyk, Andy Meyer, Tom Meteyer, Howard Smith, Robert E. Hormann and Dean E. Cress
Mol Ther 9: S382-S382; doi:10.1016/j.ymthe.2004.06.937
1000. Introns of the Angiotensin II Type 2 Receptor (AT2) Enhance Its Adenoviral-Mediated Over-Expression In Vitro
Hongwei Li, Yongxin Gao, Mohan K. Raizada and Colin Sumners
Mol Ther 9: S383-S383; doi:10.1016/j.ymthe.2004.06.938
1001. Use of cHS4 Chromatin Insulator To Improve Efficacy and Safety of Retrovirus Vectors
David W. Emery, Mari Aker, Tamon Nishino, Julie Tubb and George Stamatoyannopoulos
Mol Ther 9: S383-S383; doi:10.1016/j.ymthe.2004.06.939
1002. Immune Responses to AAV and to Factor IX in a Phase I Study of AAV-Mediated, Liver-Directed Gene Transfer for Hemophilia B
Katherine High, Catherine Manno, Denise Sabatino, Sylvia Hutchison, Michael Dake, Mahmood Razavi, Robin Kaye, Valder Aruda, Roland Herzog, Pradip Rustagi, John Rasko, Keith Hoots, Phillip Blatt, Jurg Sommer, Margaret Ragni, Margareth Ozelo, Barbara Konkle, Ruth Lessard, Alvin Luk, Bertil Glader, Glenn Pierce, Linda Couto and Mark Kay
Mol Ther 9: S383-S384; doi:10.1016/j.ymthe.2004.06.940
1003. HIV-1-Derived Lentivirus Vector-Based Antisense Gene Therapy: Towards an Alternative Treatment for HIV/AIDS
Boro Dropulic, Laurent Humeau, Gwendolyn K. Binder, Xiaobin Lu, Vladimir Slepushkin, Randall Merling, Patricia Echeagaray, Mario Pereira, Tatiana Slepushkina, Scott Barnett, Lesia K. Dropulic, Richard Carroll, Bruce Levine, Rob Roy MacGregor and Carl H. June
Mol Ther 9: S384-S384; doi:10.1016/j.ymthe.2004.06.941
1004. Integration Analyses in ADA-Deficient SCID Patients Successfully Treated with Stem Cell Gene Therapy
A. Aiuti, B. Cassani, F. Cattaneo, G. Andolfi, M. Mirolo, A. Recchia, L. Callegaro, A. Tabucchi, F. Carlucci, S. Slavin, R. Miniero, F. Mavilio, M. G. Roncarolo and C. Bordignon
Mol Ther 9: S384-S385; doi:10.1016/j.ymthe.2004.06.942
1005. Expression of Normal Dystrophin Following Myoblast Transplantation to Duchenne Muscular Dystrophy Patients
Jacques P. Tremblay, Daniel Skuk, Bouchard Jean-Pierre, Michel Sylvain, Roy Raynald, Goulet Marilyne, Roy Brigitte, Pierre Chapdelaine, Dugr|[eacute]| Francine, Jean-Guy Lachance, Louise Desch|[egrave]|nes and H|[eacute]|l|[egrave]|ne Senay
Mol Ther 9: S385-S385; doi:10.1016/j.ymthe.2004.06.943
1006. Preliminary Results of a Phase I Trial Using Retroviral Gene Transfer of G156A MGMT To Protect Hematopoiesis during BG and BCNU Therapy of Advanced Malignancies
Jane Reese, Karen Lingas, Pamela Ksenich, Colin Sweeney, Omer Koc and Stanton Gerson
Mol Ther 9: S385-S385; doi:10.1016/j.ymthe.2004.06.944
1007. Safety of Adenoviral Vectors: Results of Clinical Investigations in 445 Cancer Patients Treated with Advexin|[reg]| (Adenoviral p53) Gene Therapy
Louis A. Zumstein, Donna Call, James Merritt, Robert E. Sobol and Kerstin Menander
Mol Ther 9: S385-S386; doi:10.1016/j.ymthe.2004.06.945
1008. Intratumoral Injection of INGN 241, a Non-Replicating Adenovector Expressing the Melanoma-Differentiation Associated Gene-7 (MDA-7/IL-24): Biologic Outcome in Advanced Cancer Patients
Alex W. Tong, John Nemunaitis, Dan Su, Yuan Zhang, Casey Cunningham, Neil Senzer, George Netto, Dawn Rich, Abner Mhashilkar, Karen Parker, Keith Coffee, Rajagopal Ramesh, Suhendan Ekmekcioglu, Elizabeth A. Grimm, Jill van Wart Hood, James Merritt and Sunil Chada
Mol Ther 9: S386-S386; doi:10.1016/j.ymthe.2004.06.946
1009. A Phase I Study of the Clinical and Local Biological Effects of Intratumoral Injection of mda-7 (INGN 241) in Patients with Advanced Carcinoma
C. Casey Cunningham, Sunil Chada, James Merritt, Alex Tong, Neil Senzer, Yuan Zhang, Abner Mhashilkar, Karen Parker, Sasha Vukelja, Donald Richards, Jill Hood, Keith Coffee and John J. Nemunaitis
Mol Ther 9: S386-S386; doi:10.1016/j.ymthe.2004.06.947
1010. Interference with the IL-1 Signaling Pathway Significantly Improves the Toxicity Profile of Systemically Applied Adenovirus Vectors
Dmitry M. Shayakhmetov, Zong-Yi Li, Shaoheng Ni and Andre Lieber
Mol Ther 9: S386-S387; doi:10.1016/j.ymthe.2004.06.955
1011. Tumor Specific Oncolytic Adenovirus Vector VRX-011 Which Overproduces ADP and Has the E4 Promoter Replaced by the hTERT Promoter
Mohan Kuppuswamy, Ann E. Tollefson, Karoly Toth, Jacqueline F. Spencer, Konstantin Doronin, Drew L. Lichtenstein, Lou Zumstein and William S. M. Wold
Mol Ther 9: S387-S387; doi:10.1016/j.ymthe.2004.06.956
1012. Ad Interactions with the Complement Systems of Humans and Mice
Haixiang Jiang, Ruth Everett, Anne Kiang, Zhaoxia Wang, Huame Zhang, Delila Serra, Michael M. Frank and Andrea Amalfitano
Mol Ther 9: S387-S388; doi:10.1016/j.ymthe.2004.06.957
1013. Complement Component 3 Facilitates Ad5-Mediated Liver Transfection
Kurt R. Zinn, Tandra R. Chaudhuri, Amanda Stargel, Victor Krasnykh and Alex J. Szalai
Mol Ther 9: S388-S388; doi:10.1016/j.ymthe.2004.06.958
1014. Helper-Dependent Adenovirus Vectors Elicit Intact Innate but Attenuated Adaptive Host Immune Responses In Vivo
Daniel A. Muruve, Matthew J. Cotter, Anne K. Zaiss, Lindsay R. White, Trevor Chan, Sharon A. Clark, Joel Ross, Robert A. Meulenbroek, Gunhild M. Maelandsmo and Robin J. Parks
Mol Ther 9: S388-S388; doi:10.1016/j.ymthe.2004.06.959
1015. Induction of Protective Immunity to Anthrax Lethal Toxin with a Chimpanzee Adenovirus-Based Vaccine Carrier in the Presence of Pre-Existing Anti-Human Adenovirus Immunity
Masahiko Hashimoto, Julie L. Boyer, Neil R. Hackett, James M. Wilson and Ronald G. Crystal
Mol Ther 9: S389-S389; doi:10.1016/j.ymthe.2004.06.960
1016. Novel Chimeric Adenovirus Vaccine Vectors
Soumitra Roy, Yan Zhi, David Clawson, Guangping Gao, Gary P. Kobinger and James M. Wilson
Mol Ther 9: S389-S389; doi:10.1016/j.ymthe.2004.06.961
1017. Metabolically Biotinylated Viruses for Vector Targeting, Virus Purification, and Capsid Imaging
Samuel K. Campos, M. Brandon Parrott, Michael March, Wah Chiu and Michael A. Barry
Mol Ther 9: S390-S390; doi:10.1016/j.ymthe.2004.06.962
1018. Immune-Competent Cotton Rat Animal Model for Evaluation of Oncolytic Adenoviruses
Karoly Toth, Jacqueline F. Spencer, Ann E. Tollefson, Mohan Kuppuswamy, Konstantin Doronin, Drew L. Lichtenstein and William S. M. Wold
Mol Ther 9: S390-S390; doi:10.1016/j.ymthe.2004.06.963
1019. Immune System Regulation of Transgene Expression in the Brain 2: Differential Increase of mRNAs Encoding for Interferon-Regulated, Chemokine, and T-Cell Genes during Either Innate Acute or Chronic Systemic Adaptive Immune Responses to First Generation Adenoviral Vectors
Jeffrey M. Zirger, Carlos Barcia, Chunyan Liu, Mariana Puntel, Giovanni Sitia, Luca Guidotti, Ngan Mitchell, Iain Campbell, Maria G. Castro and Pedro R. Lowenstein
Mol Ther 9: S390-S391; doi:10.1016/j.ymthe.2004.06.964
1020. Development and Evaluation of a Genetically-Modified Adenovirus Vector That Specifically Targets Tumors Via the Bloodstream Following Systemic Administration
Masaki Akiyama, Peter W. Roelvink, David A. Einfeld, Selva Murugesan, C. Richter King and Thomas J. Wickham
Mol Ther 9: S391-S391; doi:10.1016/j.ymthe.2004.06.965
1021. VP22 Mediates Tumor Vasculature Specific Targeting
Sudhanshu P. Raikwar, Thomas A. Gardner and Chinghai Kao
Mol Ther 9: S391-S391; doi:10.1016/j.ymthe.2004.06.966
1022. Ionizing Radiation-Induced Adenovirus Infection Is Mediated by Dynamin 2
Jiong Yang, Eyad Abu-Isa, Theodore S. Lawrence and Ming Zhang
Mol Ther 9: S392-S392; doi:10.1016/j.ymthe.2004.06.967
1023. Adenoviruses Transport across a Polarized Monolayer of Caco-2 Cells by Transferrin Receptor-Mediated Transcytosis
Zeng B. Zhu, Sharmila K. Makhija, Baogen Lu, Minghui Wang, Meredith A. Preuss, Angel A. Rivera, Fen Zhou, Gene P. Siegal, Ronald D. Alvarez and David T. Curiel
Mol Ther 9: S392-S392; doi:10.1016/j.ymthe.2004.06.968
1024. Dual Targeted Vector for Multiple Myeloma Tumors and its Associated Angiogenesis
Louay K. Hallak, Jaime R. Merchan, Suzanne M. Greiner, Chris M. Storgard and Stephen J. Russell
Mol Ther 9: S392-S392; doi:10.1016/j.ymthe.2004.06.969
1025. Efficiency, Specificity and Efficacy of Genetically-Modified Adenovirus Vector on Peritoneal Cancers
Selva R. Murugesan, Masaki Akiyama, Peter W. Roelvink, David A. Einfeld, C. Richter King and Thomas J. Wickham
Mol Ther 9: S393-S393; doi:10.1016/j.ymthe.2004.06.970
1026. Targeted Measles Virotherapy for Pancreatic Cancer
Elizabeth M. Hadac, Kah-Whye Peng, Takafumi Nakamura, Laurence J. Miller and Stephen J. Russell
Mol Ther 9: S393-S393; doi:10.1016/j.ymthe.2004.06.971
1027. A 4-Week Safety Study of Reolysin|[reg]| Administered by Daily Intravenous Infusion to Cynomolgus Monkeys, with a 4-Week Recovery Period
Ken Draper, Lydia Andrews-Jones, Jeremy Evans, Matthew C. Coffey and Brad Thompson
Mol Ther 9: S393-S394; doi:10.1016/j.ymthe.2004.06.972
1028. Virus-Mediated RNAi for Skp-2 in Human Small Cell Lung Carcinoma Cells Resulted in the Inhibition of Tumor Cell Growth through the Increase of p27Kip1 and p21
Hidetoshi Sumimoto, Shizuko Yamagata, Ayako Shimizu, Makoto Miyagishi, Hiroyuki Miyoshi, Kazunari Taira and Yutaka Kawakami
Mol Ther 9: S394-S394; doi:10.1016/j.ymthe.2004.06.973
1029. Increased Fluid Secretion after Adenoviral-Mediated Transfer of the Human Aquaporin-1 cDNA to Irradiated Minipig Parotid Glands
Z. Shan, J. Li, C. Zheng, X. Liu, C. Zhang, C. M. Goldsmith, R. B. Wellner, B. J. Baum and S. Wang
Mol Ther 9: S394-S395; doi:10.1016/j.ymthe.2004.06.974
1030. Engineering Cytosine Deaminase for Suicide Gene Therapy
Margaret E. Black, Sheri D. Mahan, Greg C. Ireton, Catherine Knoeber and Barry L. Stoddard
Mol Ther 9: S395-S395; doi:10.1016/j.ymthe.2004.06.975
1031. Improved Anti-Brain Tumor Efficacy of |[Delta]||[gamma]|134.5 HSV Expressing Cytosine Deaminase
James M. Markert, M. Brad Guffey, Debbie Della Manna, Donald J. Buchsbaum, Kathleen H. Price, Catherine P. Langford and G. Yancey Gillespie
Mol Ther 9: S395-S395; doi:10.1016/j.ymthe.2004.06.976
1032. Massive Expression of a Suicide Gene Using a Replicative but Non-Disseminative Adenovirus for Treatment of Solid Tumors
Denis Bourbeau, Cara Lau, Genevieve Lavoie, Anne-Marie Mes-Masson, Josephine Nalbantoglu and Bernard Massie
Mol Ther 9: S396-S396; doi:10.1016/j.ymthe.2004.06.977
1033. A Novel Mechanism of Synergistic Cytoxicity between Prodrugs, 5-FC and GCV in Double Suicide Gene Therapy
Paul D. Boucher, Jessica O'Konek, Svend O. Freytag and Donna S. Shewach
Mol Ther 9: S396-S396; doi:10.1016/j.ymthe.2004.06.978
1034. The Optimization of Cancer Gene Therapy Using the Measurement of Viral Gene Expression Magnitude and Distribution
Kenneth N. Barton, Stephen L. Brown, Jae Ho Kim and Svend O. Freytag
Mol Ther 9: S396-S397; doi:10.1016/j.ymthe.2004.06.979
1035. Syncytia Induction Enhances the Oncolytic Potential of Vesicular Stomatitis Virus in Virotherapy for Cancer
Oliver Ebert, Katsunori Shinozaki, Chryssanthi Kournioti, Man-Seong Park, Adolfo Garcia-Sastre and Savio L. C. Woo
Mol Ther 9: S397-S397; doi:10.1016/j.ymthe.2004.06.980
1037. Site-Specific Genomic Integration in Hematopoietic Cells
Roger P. Hollis, Sarah Nightingale, Michele P. Calos, Gay M. Crooks and Donald B. Kohn
Mol Ther 9: S397-S398; doi:10.1016/j.ymthe.2004.06.982
1036. Effective Acceleration of Wound Healing by Simultaneous Transfestion of Hepatocyte Growth Factor Gene and Prostacyclin Synthase Gene Using Shima Jet
Yasuo Kunugiza, Naruya Tomita, Tetsuya Tomita, Hideo Hashimoto, Keita Yamasaki, Hiromi Koike, Hideki Yoshikawa and Ryuichi Morishita
Mol Ther 9: S397-S397; doi:10.1016/j.ymthe.2004.06.981
1038. Intramuscular Plasmid DNA Electrotransfer. Biodistribution, Degradation and Stability of the Transfectable Pool of Plasmid DNA
Michel-Francis Bureau, Naimi Sadoui, Johanne Seguin and Daniel Scherman
Mol Ther 9: S398-S398; doi:10.1016/j.ymthe.2004.06.983
1039. Mechanistic Insights into the Persistence of Non-Viral Mediated Gene Transfer In Vivo
Efren Riu, Zan Huang and Mark A. Kay
Mol Ther 9: S398-S398; doi:10.1016/j.ymthe.2004.06.984
1040. A Direct Comparison of Two Non-Viral Gene Therapy Vectors for Somatic Integration: In Vivo Evaluation of the Bacteriophage Integrase PhiC31 and the Sleeping Beauty Transposase
Anja Ehrhardt, Hui Xu, Zan Huang and Mark A. Kay
Mol Ther 9: S398-S399; doi:10.1016/j.ymthe.2004.06.985
1041. Treatment of Hyperbilirubinemia in the Gunn Rat by Intravascular Gene Transfer into Muscle with Naked Plasmid DNA (pDNA)
Istvan Danko and Zhen Jia
Mol Ther 9: S399-S399; doi:10.1016/j.ymthe.2004.06.986
1042. RNA as a Source of Transposase for Sleeping Beauty-Mediated Transposition and Long-Term Expression in Somatic Cells and Tissues
Andrew C. Wilber, Joel L. Frandsen, Lalitha R. Belur, Paul R. Score, Jennifer L. Geurts, David A. Largaespada, Perry B. Hackett and R. Scott McIvor
Mol Ther 9: S399-S400; doi:10.1016/j.ymthe.2004.06.987
1043. Spontaneous Transfection of B Lymphocytes
Mara Gerloni, Marta Rizzi, Paola Castiglioni, Matthew Wheeler and Maurizio Zanetti
Mol Ther 9: S400-S400; doi:10.1016/j.ymthe.2004.06.988
1044. Growth Hormone Releasing Hormone Plasmid Administration Decreases Tumor Growth and Enhances Immune Function in Nude Mice
Amir S. Khan, Ingrid W. Anscombe, Kathleen K. Cummings, Melissa A. Pope, Louis C. Smith and Ruxandra Draghia-Akli
Mol Ther 9: S400-S400; doi:10.1016/j.ymthe.2004.06.989
1045. Neonatal Tolerance Induction by Repetitive DNA Vaccination
An-Bang Liu, Kuo-Feng Tai and Shinn-Zong Lin
Mol Ther 9: S400-S401; doi:10.1016/j.ymthe.2004.06.990
1046. Insertional Leukemogenesis after Retroviral Gene Transfer into Murine Hematopoietic Stem Cells
Martijn H. Brugman, Monique M. A. Verstegen, Trudi P. Visser, Erna Fr|[auml]|nzel-Luiten, Manfred Schmidt, Albertus W. Wognum, Christof vonKalle and Gerard Wagemaker
Mol Ther 9: S401-S401; doi:10.1016/j.ymthe.2004.06.991
1047. BXD Recombinant Inbred Mice Represent a Novel Immune Response Model to AAV-F.IX
Huang-Ge Zhang, Hui-Chen Hsu, PingAr Yang, Qi Wu, Shaohua Yu, Jianhua Wang, Alexander Schlachterman, Katherine A. High and John D. Mountz
Mol Ther 9: S401-S402; doi:10.1016/j.ymthe.2004.06.992
1048. Long-Term Regulated Gene Expression in Non-Human Primates Using a Single Non-Recombinogenic AAV Vector
Victor M. Rivera, Lori Berk, Scott Wardwell, Hao Tang, Guang-ping Gao, Rebecca L. Grant, James M. Wilson and Tim Clackson
Mol Ther 9: S402-S402; doi:10.1016/j.ymthe.2004.06.993
1049. Engineered ZFPs Can Prevent Limb Loss in Mice
Jun Yu, Reed Hickey, Yan Huang, Edward Rebar, William C. Sessa and Frank J. Giordano
Mol Ther 9: S402-S402; doi:10.1016/j.ymthe.2004.06.994
1050. Autoimmune Anemia in Macaques Following Erythropoietin Gene Therapy
Pierre Chenuaud, Thibaut Larcher, Joe Rabinowitz, Nathalie Provost, Yan Cherel, Nicole Casadevall, Jude Samulski and Philippe Moullier
Mol Ther 9: S402-S403; doi:10.1016/j.ymthe.2004.06.995
1051. A Fail-Safe System for Gene Therapy of Parkinson's Disease; Application of Removable Expression Cassette To Prevent Overproduction of Dopamine in a Rat Model
Shin-ichi Muramatsu, Xiaog-gang Li, Takashi Okada, Mika Kodera, Yuko Nara, Naomi Takino, Kunihiko Ikeguchi, Fumi Urano, Hiroshi Ichinose, Imaharu Nakano and Keiya Ozawa
Mol Ther 9: S403-S403; doi:10.1016/j.ymthe.2004.06.996
1052. Male Germline Cells Appear To Be at Risk Following Direct Injection Gene Transfer In Utero
Paul J. Park, Joe Tellez, Gra|[ccedil]|a Almeida-Porada, Esmail D. Zanjani and Christopher D. Porada
Mol Ther 9: S403-S403; doi:10.1016/j.ymthe.2004.06.997
1053. Pharmacologically Regulated Regeneration of Functional Human Pancreatic Islets
Gary P. Kobinger, Shaoping Deng, Jean-Pierre Louboutin, Marko Vatamaniuk, Victor M. Rivera, Franz Matschinsky, James F. Markmann, Timothy P. Clackson, Steven E. Raper and James M. Wilson
Mol Ther 9: S404-S404; doi:10.1016/j.ymthe.2004.06.998
1054. Development of Adeno-Associated Virus (AAV) Vectors for Gene Therapy in the Mouse Model for Glycogen Storage Disease Type Ia (GSD-Ia)
Dwight D. Koeberl, Baodong Sun, Luis Franco, Andrew Bird, Eric Faulkner and Y.-T. Chen
Mol Ther 9: S404-S404; doi:10.1016/j.ymthe.2004.06.999
1055. Anterograde Delivery of Gene Product by rAAV5 Vectors
Kevin D. Foust, Ronald J. Mandel, Paul J. Reier and Terence R. Flotte
Mol Ther 9: S404-S405; doi:10.1016/j.ymthe.2004.06.1000
1056. PhiC31 Integrase for Long-Term Non-Viral Gene Therapy in Rat Retina
Thomas W. Chalberg, Hilary L. Genise, Douglas Vollrath and Michele P. Calos
Mol Ther 9: S405-S405; doi:10.1016/j.ymthe.2004.06.1001
1057. Successful Gene Therapy for Retinal Degenerations by Lentiviral Gene Transfer
Nobushige Tanaka, Stylianos Michalakis, Martin Biel, Franz Hofmann and Inder M. Verma
Mol Ther 9: S405-S405; doi:10.1016/j.ymthe.2004.06.1002
1058. Adeno-Associated Virus Serotype 6 (AAV-6) Vector Mediated Gene Transfer of Soluble VEGF Receptors for the Treatment of Glioblastoma Multiforme
Thomas C. Harding, Alshad S. Lalani, Jian Min Lin, Satyasri Yendluri, Bo Luan, Kathryn E. Koprivnikar, Guang Tu, Melissa A. Gonzalez-Edick, Wei Wei Wu-Prior, Melinda VanRoey, Byron Roberts, Richard LeCouter, Pete Dickinson and Karin Jooss
Mol Ther 9: S405-S406; doi:10.1016/j.ymthe.2004.06.1003
1059. The Lymphocytic Choriomeningitis Virus Envelope Glycoprotein Targets Lentivirus to Neural Progenitors in the Murine Brain
Colleen S. Stein, Ines Martins and Beverly L. Davidson
Mol Ther 9: S406-S406; doi:10.1016/j.ymthe.2004.06.1004
1060. Long Term Expression of TPP-I in Rat and Non-Human Primate Brain Following Administration of AAV2CUhCLN2, a Candidate Gene Therapy Treatment for Late Infantile Neuronal Ceroid Lipofuscinosis
Dolan Sondhi, Daniel A. Peterson, E. Lela Giannaris, Elizabeth Vassallo, Neil R. Hackett, Christine T. Sanders, Kimberly B. Bjugstad, John R. R. Sladek Jr. and Ronald G. Crystal
Mol Ther 9: S406-S407; doi:10.1016/j.ymthe.2004.06.1005
1061. Specific and Efficient Transduction of the Cochlear Inner Hair Cells with Recombinant Adeno-Associated Virus Type 3 Vector
Yuhe Liu, Takashi Okada, Tatsuya Nomoto, Kuniko Shimazaki, Kianoush Sheykholeslami, Shin-Ichi Muramatsu, Rahim Ajalli, Koichi Takeuchi, Hiroaki Mizukami, Akihiro Kume, Shuifang Xiao, Keiichi Ichimura and Keiya Ozawa
Mol Ther 9: S407-S407; doi:10.1016/j.ymthe.2004.06.1006
1062. Functional Rescue of Parkinsonian Non-Human Primates by a Dopamine Producing Multicistronic Lentiviral Vector
Bechir Jarraya, Mimoun Azzouz, James Miskin, Scott G. Ralph, Fraser Wilkes, Jonathan Rohll, Lucy E. Walmsley, Fiona Ellard, Susan M. Kingsman, Kyriacos A. Mitrophanous, Philippe Hantraye, Stephane Palphi and Nicholas D. Mazarakis
Mol Ther 9: S407-S407; doi:10.1016/j.ymthe.2004.06.1007
1063. In Utero |[beta]|-Glucuronidase Gene Transfer with AAV Vectors Results in Widespread Transduction, Enzyme Activity, and Disease Correction in the MPS VII Mouse Brain
Brian A. Karolewski and John H. Wolfe
Mol Ther 9: S407-S408; doi:10.1016/j.ymthe.2004.06.1008
1064. AdPEDF Therapy for Subfoveal Choroidal Neovascularization (CNV): Preliminary Phase I Results
Timothy Stout, Michael Klein, Eric Holz, Anurag Gupta, David Saperstein, Lisa L. Wei, Angelita Ray, Paul Kessler, Robert N. Frank and Peter A. Campochiaro
Mol Ther 9: S408-S408; doi:10.1016/j.ymthe.2004.06.1009
