TABLE OF CONTENTS

Volume 9, Issue 1 (January 2004)

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Editorial

The NIH Roadmap

Inder M. Verma

Mol Ther 9: 1; doi:10.1016/j.ymthe.2004.11.048

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Inside this Month

Inside This Month

Mol Ther 9: 2; doi:10.1016/j.ymthe.2004.11.049

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Research Update

Research Update

Mol Ther 9: 3-4; doi:10.1016/j.ymthe.2004.11.050

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Reviews

Chance or necessity? Insertional Mutagenesis in Gene Therapy and Its Consequences

Christopher Baum, Christof von Kalle, Frank J. T. Staal, Zhixiong Li, Boris Fehse, Manfred Schmidt, Floor Weerkamp, Stefan Karlsson, Gerard Wagemaker and David A. Williams

Mol Ther 9: 5-13; doi:10.1016/j.ymthe.2003.10.013

Myoblast Transplantation for Cardiac Repair: A Clinical Perspective

Husnain Kh Haider, Alvin C. K. Tan, Salim Aziz, Juan C. Chachques and Eugene K. W. Sim

Mol Ther 9: 14-23; doi:10.1016/j.ymthe.2003.10.009

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Original Articles

Reversal of Ongoing Thermal Hyperalgesia in Mice by a Recombinant Herpesvirus that Encodes Human Preproenkephalin

David C. Yeomans, Toni Jones, Charles E. Laurito, Ying Lu and Steven P. Wilson

Mol Ther 9: 24-29; doi:10.1016/j.ymthe.2003.10.008

Improved Effects of Viral Gene Delivery of Human uPA plus Biliodigestive Anastomosis Induce Recovery from Experimental Biliary Cirrhosis

Alejandra Miranda-Díaz, Ana Rosa Rincón, Silvia Salgado, José Vera-Cruz, Javier Gálvez, Ma Cristina Islas, Jaime Berumen, Estuardo Aguilar-Cordova and Juan Armendáriz-Borunda

Mol Ther 9: 30-37; doi:10.1016/j.ymthe.2003.09.015

Gene Therapy for Liver Transplantation Using Adenoviral Vectors: CD40–CD154 Blockade by Gene Transfer of CD40Ig Protects Rat Livers from Cold Ischemia and Reperfusion Injury

Bibo Ke, Xiu-Da Shen, Feng Gao, Ronald W. Busuttil, Pedro R. Löwenstein, Maria G. Castro and Jerzy W. Kupiec-Weglinski

Mol Ther 9: 38-45; doi:10.1016/j.ymthe.2003.10.011

Insulin-like Growth Factor I Plasmid Therapy Promotes in Vivo Angiogenesis

Eric D. Rabinovsky and Ruxandra Draghia-Akli

Mol Ther 9: 46-55; doi:10.1016/j.ymthe.2003.10.003

Anti-Tumor Efficacy of Human Angiostatin Using Liver-Mediated Adeno-Associated Virus Gene Therapy

Alshad S. Lalani, Betty Chang, Jian Min Lin, Scott S. Case, Bo Luan, Wei-Wei Wu-Prior, Melinda VanRoey and Karin Jooss

Mol Ther 9: 56-66; doi:10.1016/j.ymthe.2003.10.001

Adenovirus-Mediated Transfer of a Minigene Expressing Multiple Isoforms of VEGF Is More Effective at Inducing Angiogenesis Than Comparable Vectors Expressing Individual VEGF cDNAs

Paul R. Whitlock, Neil R. Hackett, Philip L. Leopold, Todd K. Rosengart and Ronald G. Crystal

Mol Ther 9: 67-75; doi:10.1016/j.ymthe.2003.09.014

Ligand-Modified Vesicular Stomatitis Virus Glycoprotein Displays a Temperature-Sensitive Intracellular Trafficking and Virus Assembly Phenotype

Ghiabe H. Guibinga, Frederick L. Hall, Erlinda M. Gordon, Erkki Ruoslahti and Theodore Friedmann

Mol Ther 9: 76-84; doi:10.1016/j.ymthe.2003.09.018

Efficient Retroviral Vector Targeting of Carcinoembryonic Antigen-Positive Tumors

Simon Chowdhury, Kerry A. Chester, John Bridgewater, Mary K. Collins and Francisco Martin

Mol Ther 9: 85-92; doi:10.1016/j.ymthe.2003.10.004

Lentivectors for Regulated and Reversible Cutaneous Gene Delivery

Zurab Siprashvili and Paul A. Khavari

Mol Ther 9: 93-100; doi:10.1016/j.ymthe.2003.09.016

Transduction Patterns of Pseudotyped Lentiviral Vectors in the Nervous System

Liang-Fong Wong, Mimoun Azzouz, Lucy E. Walmsley, Zoe Askham, Fraser J. Wilkes, Kyriacos A. Mitrophanous, Susan M. Kingsman and Nicholas D. Mazarakis

Mol Ther 9: 101-111; doi:10.1016/j.ymthe.2003.09.017

Morphological Analysis and Lentiviral Transduction of Fetal Monkey Bone Marrow-Derived Mesenchymal Stem Cells

Chang I. Lee, Donald B. Kohn, Jason E. Ekert and Alice F. Tarantal

Mol Ther 9: 112-123; doi:10.1016/j.ymthe.2003.09.019

Toward PKU Enzyme Replacement Therapy: PEGylation with Activity Retention for Three Forms of Recombinant Phenylalanine Hydroxylase

Alejandra Gámez, Lin Wang, Mary Straub, Marianne G. Patch and Raymond C. Stevens

Mol Ther 9: 124-129; doi:10.1016/j.ymthe.2003.11.002

Delivery and Protection of Adenoviruses Using Biocompatible Hydrogels for Localized Gene Therapy

Rachel Maddox Schek, Scott J. Hollister and Paul H. Krebsbach

Mol Ther 9: 130-138; doi:10.1016/j.ymthe.2003.10.002

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Erratum

Corrigendum to "The Effect of Sequestration by Nontarget Tissues on Anti-tumor Efficacy of Systemically Applied, Conditionally Replicating Adenovirus Vectors"

Kathrin M. Bernt, Shaoheng Ni, Zong-Yi Li, Dmitry M. Shayakhmetov and André Lieber

Mol Ther 9: 139; doi:10.1016/j.ymthe.2003.11.001

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