TABLE OF CONTENTS
Volume 8, Issue 6 (December 2003)
Inside This Month |
Research Updates |
Letter to The Editor |
Original Articles |
Method
Editorials
Contradictions and Extremes
Inder M. Verma
Mol Ther 8: 863; doi:10.1016/j.ymthe.2003.10.007
Inside This Month
Top of pageResearch Updates
Top of pageLetter to The Editor
A New Peptide Ligand That Targets Particles and Heterologous Proteins to Hepatocytes in Vivo
Alex V. Sokoloff, So C. Wong, James J. Ludtke, Magdolna G. Sebestyén, Vladimir M. Subbotin, Guofeng Zhang, Tatyana Budker, Marcus Bachhuber, Yoshihiro Sumita and Jon A. Wolff
Mol Ther 8: 867-872; doi:10.1016/j.ymthe.2003.09.009
In Vivo PET Imaging of Gene Expression in Parkinsonian Monkeys
J. L. Eberling, J. Cunningham, P. Pivirotto, J. Bringas, M. M. Daadi and K. S. Bankiewicz
Mol Ther 8: 873-875; doi:10.1016/j.ymthe.2003.09.013
Original Articles
Ex Vivo Gene Therapy Using Bone Marrow-Derived Cells: Combined Effects of Intracerebral and Intravenous Transplantation in a Mouse Model of Niemann–Pick Disease
Hee-Kyung Jin and Edward H. Schuchman
Mol Ther 8: 876-885; doi:10.1016/j.ymthe.2003.07.008
Effect of Intranasal Administration of Semliki Forest Virus Recombinant Particles Expressing Reporter and Cytokine Genes on the Progression of Experimental Autoimmune Encephalomyelitis
Alan Jerusalmi, Margaret M. Morris-Downes, Brian J. Sheahan and Gregory J. Atkins
Mol Ther 8: 886-894; doi:10.1016/j.ymthe.2003.09.010
Persistent Phenotypic Correction of Central Diabetes Insipidus Using Adeno-associated Virus Vector Expressing Arginine–Vasopressin in Brattleboro Rats
Junichi Ideno, Hiroaki Mizukami, Kazufumi Honda, Takashi Okada, Yutaka Hanazono, Akihiro Kume, Toshikazu Saito, Shun Ishibashi and Keiya Ozawa
Mol Ther 8: 895-902; doi:10.1016/j.ymthe.2003.08.019
Adeno-associated Virus-mediated Gene Transfer of a Secreted Decoy Human Macrophage Scavenger Receptor Reduces Atherosclerotic Lesion Formation in LDL Receptor Knockout Mice
Johanna Jalkanen, Pia Leppänen, Katri Pajusola, Outi Närvänen, Anssi Mähönen, Elisa Vähäkangas, David R. Greaves, Hansruedi Büeler and Seppo Ylä-Herttuala
Mol Ther 8: 903-910; doi:10.1016/j.ymthe.2003.09.012
Self-Complementary Adeno-associated Virus Serotype 2 Vector: Global Distribution and Broad Dispersion of AAV-Mediated Transgene Expression in Mouse Brain
Haiyan Fu, Joseph Muenzer, Richard J. Samulski, George Breese, Jerillyn Sifford, Xinhua Zeng and Douglas M. McCarty
Mol Ther 8: 911-917; doi:10.1016/j.ymthe.2003.08.021
Successful Transgene Expression with Serial Doses of Aerosolized rAAV2 Vectors in Rhesus Macaques
Anne C. Fischer, Suzanne E. Beck, Carolina I. Smith, Beth L. Laube, Frederic B. Askin, Sandra E. Guggino, Robert J. Adams, Terence R. Flotte and William B. Guggino
Mol Ther 8: 918-926; doi:10.1016/j.ymthe.2003.08.015
Transient Increase in Lung Epithelial Tight Junction Permeability: An Additional Mechanism for Enhancement of Lung Transgene Expression by Perfluorochemical Liquids
Daniel J. Weiss, Travis Beckett, Laura Bonneau, Jadrien Young, Jay K. Kolls and Guoshun Wang
Mol Ther 8: 927-935; doi:10.1016/j.ymthe.2003.09.003
Transfection of Airway Epithelium by Stable PEGylated Poly-L-lysine DNA Nanoparticles in Vivo
Assem-Galal Ziady, Christopher R. Gedeon, Timothy Miller, William Quan, Jennifer M. Payne, Susannah L. Hyatt, Tamara L. Fink, Osman Muhammad, Sharon Oette, Tomasz Kowalczyk, Murali K. Pasumarthy, Robert C. Moen, Mark J. Cooper and Pamela B. Davis
Mol Ther 8: 936-947; doi:10.1016/j.ymthe.2003.07.007
Minimal Toxicity of Stabilized Compacted DNA Nanoparticles in the Murine Lung
Assem-Galal Ziady, Christopher R. Gedeon, Osman Muhammad, Virginia Stillwell, Sharon M. Oette, Tamara L. Fink, Will Quan, Tomasz H. Kowalczyk, Susannah L. Hyatt, Jennifer Payne, Angela Peischl, J. E. Seng, Robert C. Moen, Mark J. Cooper and Pamela B. Davis
Mol Ther 8: 948-956; doi:10.1016/j.ymthe.2003.09.002
Deoxyribonuclease II is a Lysosomal Barrier to Transfection
Dasein Pinto-González Howell, Ronald J. Krieser, Alan Eastman and Michael A. Barry
Mol Ther 8: 957-963; doi:10.1016/j.ymthe.2003.09.011
Efficacy of Targeted FasL in Nasopharyngeal Carcinoma
Jian-Hua Li, Wei Shi, Marie Chia, Otto Sanchez-Sweatman, Christopher Siatskas, Dolly Huang, Pierre Busson, Henry Klamut, Wen-Chen Yeh, Chris Richardson, Brian O'Sullivan, Pat Gullane, Peter Neligan, Jeff Medin and Fei-Fei Liu
Mol Ther 8: 964-973; doi:10.1016/j.ymthe.2003.08.018
Retrovirally Transduced Muscle-Derived Cells Contribute to Hematopoiesis at Very Low Levels in the Nonhuman Primate Model
Chunji Gao, Elizabeth M. Kang, Ken Kuramoto, Brian A. Agricola, Mark Metzger, Christof von Kalle, Robert E. Donahue and John F. Tisdale
Mol Ther 8: 974-980; doi:10.1016/j.ymthe.2003.08.017
Induction of Transgene-Specific Immunological Tolerance in Myeloablated Nonhuman Primates Using Lentivirally Transduced CD34+ Progenitor Cells
Sam K. P. Kung, Dong-Sung An, Aylin Bonifacino, Mark E. Metzger, Gene-Errol Ringpis, Si-Hua Mao, Irvin S. Y. Chen and Robert E. Donahue
Mol Ther 8: 981-991; doi:10.1016/j.ymthe.2003.08.020
Needle-Free Topical Electroporation Improves Gene Expression from Plasmids Administered in Porcine Skin
Shawn Babiuk, Maria E. Baca-Estrada, Marianna Foldvari, Lawrence Baizer, Richard Stout, Michael Storms, Dietmar Rabussay, Georg Widera and Lorne Babiuk
Mol Ther 8: 992-998; doi:10.1016/j.ymthe.2003.09.008
Method
In Vivo Trans-splicing of 5' and 3' Segments of Pre-mRNA Directed by Corresponding DNA Sequences Delivered by Gene Transfer
Robert G. Pergolizzi, Alexander E. Ropper, Rachel Dragos, Alicia C. Reid, Katsutoshi Nakayama, Yadi Tan, John R. Ehteshami, Struhan H. Coleman, Randi B. Silver, Neil R. Hackett, André Menez and Ronald G. Crystal
Mol Ther 8: 999-1008; doi:10.1016/j.ymthe.2003.08.022
Detection of Replication-Competent Adenoviruses Spiked into Recombinant Adenovirus Vector Products by Infectivity PCR
Akiko Ishii-Watabe, Eriko Uchida, Akiko Iwata, Ryuji Nagata, Kouei Satoh, Kejun Fan, Mitsuhiro Murata, Hiroyuki Mizuguchi, Nana Kawasaki, Toru Kawanishi, Teruhide Yamaguchi and Takao Hayakawa
Mol Ther 8: 1009-1016; doi:10.1016/j.ymthe.2003.09.001

