TABLE OF CONTENTS
Volume 8, Issue 5 (November 2003)
Editorial
Plus ça Change...
Theodore Friedmann
Mol Ther 8: 701; doi:10.1016/j.ymthe.2003.09.006
Inside This Month
Top of pageResearch Updates
Top of pagePerspective
Oncolytic Adenovirus: Getting There Is Half the Battle
P. Joel Ross and Robin J. Parks
Mol Ther 8: 705-706; doi:10.1016/j.ymthe.2003.09.005
Original Articles
A Therapeutic Strategy Uses Histone Deacetylase Inhibitors to Modulate the Expression of Genes Involved in the Pathogenesis of Rheumatoid Arthritis
Yih-Lin Chung, Ming-Yuan Lee, Ae-June Wang and Lin-Fen Yao
Mol Ther 8: 707-717; doi:10.1016/S1525-0016(03)00235-1
Improvement of Skeletal Lesions in Mice with Mucopolysaccharidosis Type VII by Neonatal Adenoviral Gene Transfer
Arihiko Kanaji, Motomichi Kosuga, Xiao-Kang Li, Yasuyuki Fukuhara, Akiko Tanabe, Yuko Kamata, Noriyuki Azuma, Masao Yamada, Toyonori Sakamaki, Yoshiaki Toyama and Torayuki Okuyama
Mol Ther 8: 718-725; doi:10.1016/j.ymthe.2003.07.004
Optimization of Adenoviral Vectors to Direct Highly Amplified Prostate-Specific Expression for Imaging and Gene Therapy
Makoto Sato, Mai Johnson, Liqun Zhang, Baohui Zhang, Kim Le, Sanjiv S. Gambhir, Michael Carey and Lily Wu
Mol Ther 8: 726-737; doi:10.1016/j.ymthe.2003.08.016
Electrochemo-Gene Therapy of Cancer: Intratumoral Delivery of Interleukin-12 Gene and Bleomycin Synergistically Induced Therapeutic Immunity and Suppressed Subcutaneous and Metastatic Melanomas in Mice
Tsunao Kishida, Hidetsugu Asada, Yoshiki Itokawa, Kakei Yasutomi, Masaharu Shin-Ya, Satoshi Gojo, Feng-De Cui, Yuji Ueda, Hisakazu Yamagishi, Jiro Imanishi and Osam Mazda
Mol Ther 8: 738-745; doi:10.1016/j.ymthe.2003.08.002
The Effect of Sequestration by Nontarget Tissues on Anti-tumor Efficacy of Systemically Applied, Conditionally Replicating Adenovirus Vectors
Kathrin M. Bernt, Shaoheng Ni, Zong-Yi Li, Dmitry M. Shayakhmetov and André Lieber
Mol Ther 8: 746-755; doi:10.1016/j.ymthe.2003.07.006
MLV/HIV-Pseudotyped Vectors: A New Treatment Option for Cutaneous T Cell Lymphomas
Sonja Thaler, Angelika M. Burger, Thomas Schulz and Barbara S. Schnierle
Mol Ther 8: 756-761; doi:10.1016/S1525-0016(03)00241-7
In Vitro and in Vivo Growth Suppression of Human Papillomavirus 16-Positive Cervical Cancer Cells by E6 siRNA
Mitsuo Yoshinouchi, Taketo Yamada, Masahiro Kizaki, Jin Fen, Takeyoshi Koseki, Yasuo Ikeda, Tatsuji Nishihara and Kenji Yamato
Mol Ther 8: 762-768; doi:10.1016/j.ymthe.2003.08.004
Small Interfering RNA Inhibits Hepatitis B Virus Replication in Mice
Hilla Giladi, Mali Ketzinel-Gilad, Ludmila Rivkin, Yaakov Felig, Ofer Nussbaum and Eithan Galun
Mol Ther 8: 769-776; doi:10.1016/S1525-0016(03)00244-2
Lentiviral Vectors Pseudotyped with Minimal Filovirus Envelopes Increased Gene Transfer in Murine Lung
Maria Fe Medina, Gary P. Kobinger, John Rux, Mehdi Gasmi, David J. Looney, Paul Bates and James M. Wilson
Mol Ther 8: 777-789; doi:10.1016/j.ymthe.2003.07.003
Transcriptional and Posttranslational Regulation of Cre Recombinase by RU486 as the Basis for an Enhanced Inducible Expression System
Stephanos Kyrkanides, Jen-nie H. Miller, William J. Bowers and Howard J. Federoff
Mol Ther 8: 790-795; doi:10.1016/j.ymthe.2003.07.005
Engineered Long Terminal Repeats of Retroviral Vectors Enhance Transgene Expression in Hepatocytes in Vitro and in Vivo
Kanji Yamaguchi, Katsuhiko Itoh, Naoki Ohnishi, Yoshito Itoh, Christopher Baum, Takashi Tsuji, Toshikazu Nagao, Hiroaki Higashitsuji, Takeshi Okanoue and Jun Fujita
Mol Ther 8: 796-803; doi:10.1016/j.ymthe.2003.08.005
A Stable Murine-Based RD114 Retroviral Packaging Line Efficiently Transduces Human Hematopoietic Cells
Maureen Ward, Rose Sattler, I. Robert Grossman, Anthony J. Bell Jr., Donna Skerrett, Laxmi Baxi and Arthur Bank
Mol Ther 8: 804-812; doi:10.1016/j.ymthe.2003.07.002
Characterization of in Vitro and in Vivo Gene Transfer Properties of Adenovirus Serotype 35 Vector
Fuminori Sakurai, Hiroyuki Mizuguchi, Teruhide Yamaguchi and Takao Hayakawa
Mol Ther 8: 813-821; doi:10.1016/S1525-0016(03)00243-0
Rat Strain Differences in the Ectopic Osteogenic Potential of Recombinant Human BMP Adenoviruses
Jin Zhong Li, Hongwei Li, Brad Dunford, David Holman, Brian Beres, Debra D. Pittman, Gerald R. Hankins and Gregory A. Helm
Mol Ther 8: 822-829; doi:10.1016/j.ymthe.2003.08.013
Certification Assays for HIV-1-Based Vectors: Frequent Passage of Gag Sequences without Evidence of Replication-Competent Viruses
Lakshmi Sastry, Yi Xu, Terry Johnson, Kunal Desai, David Rissing, Jonathan Marsh and Kenneth Cornetta
Mol Ther 8: 830-839; doi:10.1016/j.ymthe.2003.08.003
VP22-Mediated and Light-Activated Delivery of an Anti-c-raf1 Antisense Oligonucleotide Improves Its Activity after Intratumoral Injection in Nude Mice
David Zavaglia, Nadia Normand, Neil Brewis, Peter O'Hare, Marie-Christine Favrot and Jean-luc Coll
Mol Ther 8: 840-845; doi:10.1016/j.ymthe.2003.08.001
Methods
Improved System for Helper-Dependent Adenoviral Vector Production
Donna Palmer and Philip Ng
Mol Ther 8: 846-852; doi:10.1016/j.ymthe.2003.08.014
Baculovirus Capsid Display: A Novel Tool for Transduction Imaging
Sari P. Kukkonen, Kari J. Airenne, Varpu Marjomäki, Olli H. Laitinen, Pauliina Lehtolainen, Pasi Kankaanpää, Anssi J. Mähönen, Jani K. Räty, Henri R. Nordlund, Christian Oker-Blom, Markku S. Kulomaa and Seppo Ylä-Herttuala
Mol Ther 8: 853-862; doi:10.1016/j.ymthe.2003.07.009
