TABLE OF CONTENTS
Volume 8, Issue 4 (October 2003)
Editorial
Fraud and Deception in Science
Inder M. Verma
Mol Ther 8: 519; doi:10.1016/j.ymthe.2003.08.006
Inside This Month
Top of pageResearch Updates
Top of pageBook Review
Top of pagePerspective
HIV-1 Vif: Counteracting Innate Antiretroviral Defenses
Bryan R. Cullen
Mol Ther 8: 525-527; doi:10.1016/j.ymthe.2003.08.010
Large animal models: Bridging the gap
Stephen L. Hart
Mol Ther 8: 528-529; doi:10.1016/j.ymthe.2003.08.012
Original Articles
Treatment of Rat Gliosarcoma Brain Tumors by HSV-Based Multigene Therapy Combined with Radiosurgery
Ajay Niranjan, Darren Wolfe, Masakazu Tamura, M. Karina Soares, David M. Krisky, L. Dade Lunsford, Songhui Li, Wendy Fellows-Mayle, Neal A. DeLuca, Justus B. Cohen and Joseph C. Glorioso
Mol Ther 8: 530-542; doi:10.1016/S1525-0016(03)00232-6
HSV-1 Therapy of Primary Tumors Reduces the Number of Metastases in an Immune-Competent Model of Metastatic Breast Cancer
Darby L. Thomas and Nigel W. Fraser
Mol Ther 8: 543-551; doi:10.1016/S1525-0016(03)00236-3
Interleukin (IL)-21 and IL-15 Genetic Transfer Synergistically Augments Therapeutic Antitumor Immunity and Promotes Regression of Metastatic Lymphoma
Tsunao Kishida, Hidetsugu Asada, Yoshiki Itokawa, Feng-De Cui, Masaharu Shin-Ya, Satoshi Gojo, Kakei Yasutomi, Yuji Ueda, Hisakazu Yamagishi, Jiro Imanishi and Osam Mazda
Mol Ther 8: 552-558; doi:10.1016/S1525-0016(03)00222-3
Boosting with Recombinant Vaccinia Increases HPV-16 E7-Specific T Cell Precursor Frequencies and Antitumor Effects of HPV-16 E7-Expressing Sindbis Virus Replicon Particles
Cheng-Tao Lin, Chien-Fu Hung, Jeremy Juang, Liangmei He, Ken-Yu Lin, Tae WooKim and T.-C. Wu
Mol Ther 8: 559-566; doi:10.1016/S1525-0016(03)00238-7
Transcriptional Targeting of Dendritic Cells in Gene Gun-Mediated DNA Immunization Favors the Induction of Type 1 Immune Responses
Stephan Sudowe, Isis Ludwig-Portugall, Evelyn Montermann, Ralf Ross and Angelika B. Reske-Kunz
Mol Ther 8: 567-575; doi:10.1016/S1525-0016(03)00242-9
Macrophage Apolipoprotein A-I Expression Protects Against Atherosclerosis in ApoE-Deficient Mice and Up-regulates ABC Transporters
Yan Ru Su, Hiroyuki Ishiguro, Amy S. Major, Dwayne E. Dove, Wenwu Zhang, Alyssa H. Hasty, Vladimir R. Babaev, MacRae F. Linton and Sergio Fazio
Mol Ther 8: 576-583; doi:10.1016/S1525-0016(03)00214-4
Adenoviral-delivered Angiopoietin-1 Reduces the Infarction and Attenuates the Progression of Cardiac Dysfunction in the Rat Model of Acute Myocardial Infarction
Kazuhiro Takahashi, Yoshinori Ito, Masayuki Morikawa, Masayoshi Kobune, Jianhua Huang, Masaru Tsukamoto, Katsunori Sasaki, Kiminori Nakamura, Hironari Dehari, Katsuya Ikeda, Hiroaki Uchida, Sachie Hirai, Tomio Abe and Hirofumi Hamada
Mol Ther 8: 584-592; doi:10.1016/S1525-0016(03)00230-2
Long-Term Correction of Bilirubin UDPglucuronyltransferase Deficiency in Rats by in Utero Lentiviral Gene Transfer
Jurgen Seppen, Roos van der Rijt, Norbert Looije, Niek P. van Til, Wouter H. Lamers and Ronald P. J. Oude Elferink
Mol Ther 8: 593-599; doi:10.1016/S1525-0016(03)00234-X
Phenotype Correction of Fanconi Anemia Group a Hematopoietic Stem Cells Using Lentiviral Vector
Kaoru Yamada, Ali Ramezani, Robert G. Hawley, Wolfram Ebell, Fre Arwert, Larry W. Arnold and Christopher E. Walsh
Mol Ther 8: 600-610; doi:10.1016/S1525-0016(03)00223-5
Direct Comparison of RD114-Pseudotyped Versus Amphotropic-Pseudotyped Retroviral Vectors for Transduction of Rhesus Macaque Long-Term Repopulating Cells
Jiong Hu, Patrick Kelly, Aylin Bonifacino, Brian Agricola, Robert Donahue, Elio Vanin and Cynthia E. Dunbar
Mol Ther 8: 611-617; doi:10.1016/S1525-0016(03)00239-9
Enforced Adenoviral Vector-Mediated Expression of HOXB4 in Human Umbilical Cord Blood cd34+ Cells Promotes Myeloid Differentiation but not Proliferation
Ann C. M. Brun, Xiaolong Fan, Jon Mar Björnsson, R. Keith Humphries and Stefan Karlsson
Mol Ther 8: 618-628; doi:10.1016/S1525-0016(03)00237-5
Optimization of Gene Expression in Nonactivated Circulating Lymphocytes
Yufeng Zhang, Huanzhang Lu, Patricia LiWang, Uluhan Sili and Nancy Smyth Templeton
Mol Ther 8: 629-636; doi:10.1016/S1525-0016(03)00231-4
Targeting Expression of a Transgene to the Airway Surface Epithelium Using a Ciliated Cell-Specific Promoter
Lawrence E. Ostrowski, James R. Hutchins, Kelly Zakel and Wanda K. O'Neal
Mol Ther 8: 637-645; doi:10.1016/S1525-0016(03)00221-1
Transfection Efficiency and Toxicity Following Delivery of Naked Plasmid DNA and Cationic Lipid–DNA Complexes to Ovine Lung Segments
Michael Emerson, Louise Renwick, Stephen Tate, Susan Rhind, Elspeth Milne, Hazel Painter (née Alsop), A. Christopher Boyd, Gerry McLachlan, Uta Griesenbach, Seng H. Cheng, Deborah R. Gill, Stephen C. Hyde, Alison Baker, Eric W. Alton, David J. Porteous and D. David S. Collie
Mol Ther 8: 646-653; doi:10.1016/S1525-0016(03)00233-8
Helper-Independent Sleeping Beauty Transposon–Transposase Vectors for Efficient Nonviral Gene Delivery and Persistent Gene Expression in Vivo
Jacob Giehm Mikkelsen, Stephen R. Yant, Leonard Meuse, Zan Huang, Hui Xu and Mark A. Kay
Mol Ther 8: 654-665; doi:10.1016/S1525-0016(03)00216-8
Generation of Transgenic Mice Using Lentiviral Vectors: A Novel Preclinical Assessment of Lentiviral Vectors for Gene Therapy
Masahito Ikawa, Nobushige Tanaka, Winston W.-Y. Kao and Inder M. Verma
Mol Ther 8: 666-673; doi:10.1016/S1525-0016(03)00240-5
Global Analysis of Cellular Transcription Following Infection with An HIV-Based Vector
Richard Mitchell, Chih-Yuan Chiang, Charles Berry and Frederic Bushman
Mol Ther 8: 674-687; doi:10.1016/S1525-0016(03)00215-6
