A Voluntary Moratorium?

Inder M. Verma

Mol Ther 7: 141; doi:10.1016/S1525-0016(03)00009-1

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Inside this Month

Mol Ther 7: 142; doi:10.1016/S1525-0016(03)00020-0

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Research Update

Mol Ther 7: 143; doi:10.1016/S1525-0016(03)00028-5

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"Man's Best Friend": A New Model System for Cancer Therapeutics?

John G. Hay

Mol Ther 7: 144-145; doi:10.1016/S1525-0016(03)00007-8

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VP22 Flips the Switch on Cell Death

Matthew D. Weitzman

Mol Ther 7: 146-147; doi:10.1016/S1525-0016(03)00006-6

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Gene Therapy for Asthma

Phillip Factor

Mol Ther 7: 148-152; doi:10.1016/S1525-0016(03)00003-0

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Immune Gene Therapy for Kidney Cancer: The Search for a Magic Trigger

Hyung L. Kim, Arie S. Belldegrun and Robert A. Figlin

Mol Ther 7: 153-154; doi:10.1016/S1525-0016(02)00048-5

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Treatment of Experimental Asthma by Long-Term Gene Therapy Directed against IL-4 and IL-13

Tatiana Zavorotinskaya, Adrian Tomkinson and John E. Murphy

Mol Ther 7: 155-162; doi:10.1016/S1525-0016(02)00050-3

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A Canine Conditionally Replicating Adenovirus for Evaluating Oncolytic Virotherapy in a Syngeneic Animal Model

Akseli Hemminki, Anna Kanerva, Eric J. Kremer, Gerd J. Bauerschmitz, Bruce F. Smith, Bin Liu, Minghui Wang, Renee A. Desmond, Anne Keriel, Brian Barnett, Henry J. Baker, Gene P. Siegal and David T. Curiel

Mol Ther 7: 163-173; doi:10.1016/S1525-0016(02)00049-7

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Systemic Administration of a Recombinant Adenovirus Encoding a HSA–Angiostatin Kringle 1–3 Conjugate Inhibits MDA-MB-231 Tumor Growth and Metastasis in a Transgenic Model of Spontaneous Eye Cancer

C. Bouquet, E. Frau, P. Opolon, E. Connault, M. Abitbol, F. Griscelli, P. Yeh and M. Perricaudet

Mol Ther 7: 174-184; doi:10.1016/S1525-0016(02)00057-6

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IFN- Sensitization of Prostate Cancer Cells to Fas-Mediated Death: A Gene Therapy Approach

William A. Selleck, Steven E. Canfield, Waleed A. Hassen, Marcia Meseck, Alexei I. Kuzmin, Randy C. Eisensmith, Shu-Hsia Chen and Simon J. Hall

Mol Ther 7: 185-192; doi:10.1016/S1525-0016(02)00040-0

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Long-Term Correction of Glycogen Storage Disease Type II with a Hybrid Ad-AAV Vector

Bao-dong Sun, Y.-T Chen, Andrew Bird, Andrea Amalfitano and Dwight D. Koeberl

Mol Ther 7: 193-201; doi:10.1016/S1525-0016(02)00055-2

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Novel Semliki Forest Virus Vectors with Reduced Cytotoxicity and Temperature Sensitivity for Long-Term Enhancement of Transgene Expression

Kenneth Lundstrom, Alessandra Abenavoli, Antonio Malgaroli and Markus U. Ehrengruber

Mol Ther 7: 202-209; doi:10.1016/S1525-0016(02)00056-4

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Negative-Strand RNA Viral Vectors: Intravenous Application of Sendai Virus Vectors for the Systemic Delivery of Therapeutic Genes

Michael Bitzer, Guy Ungerechts, Sascha Bossow, Florian Graepler, Reinhard Sedlmeier, Sorin Armeanu, Christian Bernloehr, Martin Spiegel, Christine D. Gross, Michael Gregor, Wolfgang J. Neubert and Ulrich M. Lauer

Mol Ther 7: 210-217; doi:10.1016/S1525-0016(02)00052-7

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Helper-free HSV-1 Amplicons Elicit a Markedly Less Robust Innate Immune Response in the CNS

John A. Olschowka, William J. Bowers, Sean D. Hurley, Michael A. Mastrangelo and Howard J. Federoff

Mol Ther 7: 218-227; doi:10.1016/S1525-0016(02)00036-9

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Simultaneous Inhibition of GSK3 and GSK3 Using Hairpin siRNA Expression Vectors

Jenn-Yah Yu, Jennifer Taylor, Stacy L. DeRuiter, Anne B. Vojtek and David L. Turner

Mol Ther 7: 228-236; doi:10.1016/S1525-0016(02)00037-0

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Localized Expression of Small RNA Inhibitors in Human Cells

Cynthia P. Paul, Paul D. Good, Shirley X. L. Li, Annette Kleihauer, John J. Rossi and David R. Engelke

Mol Ther 7: 237-247; doi:10.1016/S1525-0016(02)00038-2

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Efficiency of Chimeraplast Gene Targeting by Direct Nuclear Injection Using a GFP Recovery Assay

Nam D. Tran, Xiaoming Liu, Ziying Yan, Duane Abbote, Qinshi Jiang, Eric B. Kmiec, Curt D. Sigmund and John F. Engelhardt

Mol Ther 7: 248-253; doi:10.1016/S1525-0016(02)00039-4

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Molecular Weight-Dependent Gene Transfection Activity of Unmodified and Galactosylated Polyethyleneimine on Hepatoma Cells and Mouse Liver

Kensuke Morimoto, Makiya Nishikawa, Shigeru Kawakami, Takayuki Nakano, Yoshiyuki Hattori, Shintaro Fumoto, Fumiyoshi Yamashita and Mitsuru Hashida

Mol Ther 7: 254-261; doi:10.1016/S1525-0016(02)00053-9

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Particle Assembly Incorporating a VP22–BH3 Fusion Protein, Facilitating Intracellular Delivery, Regulated Release, and Apoptosis

N. D. Brewis, A. Phelan, N. Normand, E. Choolun and P. O'Hare

Mol Ther 7: 262-270; doi:10.1016/S1525-0016(02)00054-0

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Construction of an rtTA2^s-m2/tts^kid-Based Transcription Regulatory Switch That Displays No Basal Activity, Good Inducibility, and High Responsiveness to Doxycycline in Mice and Non-Human Primates

Stefania Lamartina, Luisa Silvi, Giuseppe Roscilli, Danilo Casimiro, Adam J. Simon, Mary-Ellen Davies, John W. Shiver, Cira Daniela Rinaudo, Immacolata Zampaglione, Elena Fattori, Stefano Colloca, Odalys Gonzalez Paz, Ralph Laufer, Hermann Bujard, Riccardo Cortese, Gennaro Ciliberto and Carlo Toniatti

Mol Ther 7: 271-280; doi:10.1016/S1525-0016(02)00051-5

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Stable Genetic Modification of Human Embryonic Stem Cells by Lentiviral Vectors

Michal Gropp, Pavel Itsykson, Orna Singer, Tamir Ben-Hur, Etti Reinhartz, Eithan Galun and Benjamin E. Reubinoff

Mol Ther 7: 281-287; doi:10.1016/S1525-0016(02)00047-3

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