TABLE OF CONTENTS

Volume 6, Issue 1 (July 2002)

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Editorial

Hypothesis-Driven Science

Inder M. Verma

Mol Ther 6: 1; doi:10.1006/mthe.2002.0622

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Issue

Gene Therapy and the Germ Line

Trisha Gura

Mol Ther 6: 2-4; doi:10.1006/mthe.2002.0642

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Review

Baculovirus as Mammalian Cell Expression Vector for Gene Therapy: An Emerging Strategy

Sudip Ghosh, Md. Khalid Parvez, Kakoli Banerjee, Shiv K. Sarin and Seyed E. Hasnain

Mol Ther 6: 5-11; doi:10.1006/mthe.2000.0643

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Original Articles

Neurotrophin-3 Transduction Attenuates Cisplatin Spiral Ganglion Neuron Ototoxicity in the Cochlea

William J. Bowers, Xiaowei Chen, Huang Guo, D. Robert Frisina, Howard J. Federoff and Robert D. Frisina

Mol Ther 6: 12-18; doi:10.1006/mthe.2002.0627

Biodistribution and Toxicity Studies of VSVG-Pseudotyped Lentiviral Vector after Intravenous Administration in Mice with the Observation of in Vivo Transduction of Bone Marrow

Dao Pan, Roland Gunther, Weiming Duan, Steve Wendell, William Kaemmerer, Tal Kafri, Inder M. Verma and Chester B. Whitley

Mol Ther 6: 19-29; doi:10.1006/mthe.2002.0630

Optimizing Aptamer Activity for Gene Therapy Applications Using Expression Cassette SELEX

Robert E. Martell, Joseph R. Nevins and Bruce A. Sullenger

Mol Ther 6: 30-34; doi:10.1006/mthe.2002.0624

Deoxyribonuclease I-like III Is an Inducible Macrophage Barrier to Liposomal Transfection

Andrew Wilber, Michael Lu and Michael C. Schneider

Mol Ther 6: 35-42; doi:10.1006/mthe.2002.0625

Comparison of Surfactant and Perfluorochemical Liquid Enhanced Adenovirus-Mediated Gene Transfer in Normal Rat Lung

Daniel J. Weiss, Gökhan M. Mutlu, Laura Bonneau, Michael Mendez, Ying Wang, Vidas Dumasius and Phillip Factor

Mol Ther 6: 43-49; doi:10.1006/mthe.2002.0632

Tumor Growth Inhibition by Interferon-alpha using PEGylated Protein or Adenovirus Gene Transfer with Constitutive or Regulated Expression

G. William Demers, Duane E. Johnson, Todd Machemer, L. David Looper, Amy Batinica, Josefina C. Beltran, Barry J. Sugarman and John A. Howe

Mol Ther 6: 50-56; doi:10.1006/mthe.2002.0629

On the Kinetics of Polyplex Endocytic Trafficking: Implications for Gene Delivery Vector Design

M. Laird Forrest and Daniel W. Pack

Mol Ther 6: 57-66; doi:10.1006/mthe.2002.0631

Antisense Gene Therapy of Brain Cancer with an Artificial Virus Gene Delivery System

Yun Zhang, Chunni Zhu and William M. Pardridge

Mol Ther 6: 67-72; doi:10.1006/mthe.2002.0633

Noninvasive, Repetitive, Quantitative Measurement of Gene Expression from a Bicistronic Message by Positron Emission Tomography, Following Gene Transfer with Adenovirus

Qianwa Liang, Jeff Gotts, Nagichettiar Satyamurthy, Jorge Barrio, Michael E. Phelps, Sanjiv S. Gambhir and Harvey R. Herschman

Mol Ther 6: 73-82; doi:10.1006/mthe.2002.0626

Kinetics of Fluorescence Expression in Nonhuman Primates Transplanted with GFP Retrovirus-Modified CD34 Cells

Peter Kurre, Julia Morris, Robert G. Andrews, Donald B. Kohn and Hans-Peter Kiem

Mol Ther 6: 83-90; doi:10.1006/mthe.2002.0623

An Adenoviral Expression System for AAV Rep78 Using Homologous Recombination

Cheryl A. Carlson, Dmitry M. Shayakhmetov and André Lieber

Mol Ther 6: 91-98; doi:10.1006/mthe.2002.0634

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Methods

Restoration of a Functional Open Reading Frame by Homologous Recombination between Two Adenoviral Vectors

Cheryl A. Carlson, Dmitry M. Shayakhmetov and André Lieber

Mol Ther 6: 99-105; doi:10.1006/mthe.2002.0635

Improved Method of Recombinant AAV2 Delivery for Systemic Targeted Gene Therapy

Cathryn Mah, Thomas J. Fraites Jr., Irene Zolotukhin, Sihong Song, Terence R. Flotte, Jon Dobson, Christopher Batich and Barry J. Byrne

Mol Ther 6: 106-112; doi:10.1006/mthe.2001.0636

Blockerette-Ligated Capture T7-Amplified RT-PCR, a New Method for Determining Flanking Sequences

Todd Lenvik, Troy C. Lund and Catherine M. Verfaillie

Mol Ther 6: 113-118; doi:10.1006/mthe.2002.0637

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Trials

Evidence of CFTR Function in Cystic Fibrosis after Systemic Administration of 4-Phenylbutyrate

Pamela L. Zeitlin, Marie Diener-West, Ronald C. Rubenstein, Michael P. Boyle, Carlton K.K. Lee and Lois Brass-Ernst

Mol Ther 6: 119-126; doi:10.1006/mthe.2002.0639

Increased Vascularity Detected by Digital Subtraction Angiography after VEGF Gene Transfer to Human Lower Limb Artery: A Randomized, Placebo-Controlled, Double-Blinded Phase II Study

Kimmo Mäkinen, Hannu Manninen, Marja Hedman, Pekka Matsi, Hanna Mussalo, Esko Alhava and Seppo Ylä-Herttuala

Mol Ther 6: 127-133; doi:10.1006/mthe.2002.0638

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Corrigendum

The Effect of Cell Division on the Cellular Dynamics of Microinjected DNA and Dextran

James J. Ludtke, Magdolna G. Sebestyén and Jon A. Wolff

Mol Ther 6: 134; doi:10.1006/mthe.2002.0640

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Erratum

A Novel, Helper-Dependent, Adenovirus–Retrovirus Hybrid Vector: Stable Transduction by a Two-Stage Mechanism

Harris  Soifer, Collin  Higo, Christopher R.  Logg, Lily  Ja-Lu Jih, Toshiaki  Shichinohe, Erik  Harboe-Schmidt, Kohnosuke  Mitani and Noriyuki  Kasahara

Mol Ther 6: 135; doi:10.1006/mthe.2002.0641

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