TABLE OF CONTENTS
Volume 17, Issue 5 (May 2009)
Editorial
Recombinant DNA Advisory Committee Updates Recommendations on Gene Transfer for X-Linked Severe Combined Immunodeficiency FREE
David A Williams
Mol Ther 17: 751-752; doi:10.1038/mt.2009.76
In This Issue
In This Issue FREE
Mol Ther 17: 754; doi:10.1038/mt.2009.77
See also: Original Article by Usui et al. See also: Original Article by Ng et al. See also: Original Article by Lucie et al. See also: Original Article by Wu et al. See also: Original Article by Akinc et al. See also: Original Article by Vera et al.Research Highlights
Research Highlights
Research Highlights
Mol Ther 17: 755; doi:10.1038/mt.2009.68
Commentary
Dotting the I's and Crossing the T's: Integration Analyses in Transduced Patient T Cells
John J Rossi
Mol Ther 17: 756-757; doi:10.1038/mt.2009.75
See also: Original Article by Wang et al.Reviews
Cell-based Therapy for Heart Disease: A Clinically Oriented Perspective
Philippe Menasche
Mol Ther 17: 758-766; advance online publication, March 10, 2009; doi:10.1038/mt.2009.40
Biological Gene Delivery Vehicles: Beyond Viral Vectors
Yiqi Seow and Matthew J Wood
Mol Ther 17: 767-777; advance online publication, March 10, 2009; doi:10.1038/mt.2009.41
Original Articles
Increased Expression of Catalase and Superoxide Dismutase 2 Reduces Cone Cell Death in Retinitis Pigmentosa
Shinichi Usui, Keiichi Komeima, Sun Young Lee, Young-Joon Jo, Shinji Ueno, Brian S Rogers, Zhihao Wu, Jikui Shen, Lili Lu, Brian C Oveson, Peter S Rabinovitch and Peter A Campochiaro
Mol Ther 17: 778-786; advance online publication, March 17, 2009; doi:10.1038/mt.2009.47
Functional Cone Rescue by RdCVF Protein in a Dominant Model of Retinitis Pigmentosa
Ying Yang, Saddek Mohand-Said, Aude Danan, Manuel Simonutti, Valérie Fontaine, Emmanuelle Clerin, Serge Picaud, Thierry Léveillard and José-Alain Sahel
Mol Ther 17: 787-795; advance online publication, March 10, 2009; doi:10.1038/mt.2009.28
Suppression of Acute Lung Inflammation by Intracellular Peptide Delivery of a Nuclear Import Inhibitor
Danya Liu, Jozef Zienkiewicz, Antonio DiGiandomenico and Jacek Hawiger
Mol Ther 17: 796-802; advance online publication, March 3, 2009; doi:10.1038/mt.2009.18
AAV1/2-mediated CNS Gene Delivery of Dominant-negative CCL2 Mutant Suppresses Gliosis, 
-amyloidosis, and Learning Impairment of APP/PS1 Mice
Tomomi Kiyota, Masaru Yamamoto, Bryce Schroder, Michael T Jacobsen, Russell J Swan, Mary P Lambert, William L Klein, Howard E Gendelman, Richard M Ransohoff and Tsuneya Ikezu
Mol Ther 17: 803-809; advance online publication, March 10, 2009; doi:10.1038/mt.2009.44
Mutant Sodium Channel for Tumor Therapy
Bakhos A Tannous, Adam P Christensen, Lisa Pike, Thomas Wurdinger, Katherine F Perry, Okay Saydam, Andreas H Jacobs, Jaime García-Añoveros, Ralph Weissleder, Miguel Sena-Esteves, David P Corey and Xandra O Breakefield
Mol Ther 17: 810-819; advance online publication, March 3, 2009; doi:10.1038/mt.2009.33
Cationic PMMA Nanoparticles Bind and Deliver Antisense Oligoribonucleotides Allowing Restoration of Dystrophin Expression in the mdx Mouse
Paola Rimessi, Patrizia Sabatelli, Marina Fabris, Paola Braghetta, Elena Bassi, Pietro Spitali, Gaetano Vattemi, Giuliano Tomelleri, Lara Mari, Daniela Perrone, Alessandro Medici, Marcella Neri, Matteo Bovolenta, Elena Martoni, Nadir M. Maraldi, Francesca Gualandi, Luciano Merlini, Marco Ballestri, Luisa Tondelli, Katia Sparnacci, Paolo Bonaldo, Antonella Caputo, Michele Laus and Alessandra Ferlini
Mol Ther 17: 820-827; advance online publication, February 24, 2009; doi:10.1038/mt.2009.8
Engineering Clustered Ligand Binding Into Nonviral Vectors: 
v3 Targeting as an Example
Quinn KT Ng, Marie K Sutton, Pan Soonsawad, Li Xing, Holland Cheng and Tatiana Segura
Mol Ther 17: 828-836; advance online publication, February 24, 2009; doi:10.1038/mt.2009.11
Clustering and Internalization of Integrin v3 With a Tetrameric RGD-synthetic Peptide
Sancey Lucie, Garanger Elisabeth, Foillard Stéphanie, Schoehn Guy, Hurbin Amandine, Albiges-Rizo Corinne, Boturyn Didier, Souchier Catherine, Grichine Alexeï, Dumy Pascal and Coll Jean-Luc
Mol Ther 17: 837-843; advance online publication, March 3, 2009; doi:10.1038/mt.2009.29
Analysis of Lentiviral Vector Integration in HIV+ Study Subjects Receiving Autologous Infusions of Gene Modified CD4+ T Cells
Gary P Wang, Bruce L Levine, Gwendolyn K Binder, Charles C Berry, Nirav Malani, Gary McGarrity, Pablo Tebas, Carl H June and Frederic D Bushman
Mol Ther 17: 844-850; advance online publication, March 3, 2009; doi:10.1038/mt.2009.16
See also: Commentary by RossiTranscriptional Enhancers Induce Insertional Gene Deregulation Independently From the Vector Type and Design
Giulietta Maruggi, Simona Porcellini, Giulia Facchini, Serena K Perna, Claudia Cattoglio, Daniela Sartori, Alessandro Ambrosi, Axel Schambach, Christopher Baum, Chiara Bonini, Chiara Bovolenta, Fulvio Mavilio and Alessandra Recchia
Mol Ther 17: 851-856; advance online publication, March 17, 2009; doi:10.1038/mt.2009.51
Induction of Immune Tolerance to FIX Following Muscular AAV Gene Transfer Is AAV-dose/FIX-level Dependent
Meagan E Kelly, Jiacai Zhuo, Arpita S Bharadwaj and Hengjun Chao
Mol Ther 17: 857-863; advance online publication, February 24, 2009; doi:10.1038/mt.2009.25
Octa-guanidine Morpholino Restores Dystrophin Expression in Cardiac and Skeletal Muscles and Ameliorates Pathology in Dystrophic mdx Mice
Bo Wu, Yongfu Li, Paul A Morcos, Timothy J Doran, Peijuan Lu and Qi Long Lu
Mol Ther 17: 864-871; advance online publication, March 10, 2009; doi:10.1038/mt.2009.38
Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver
Akin Akinc, Michael Goldberg, June Qin, J Robert Dorkin, Christina Gamba-Vitalo, Martin Maier, K Narayanannair Jayaprakash, Muthusamy Jayaraman, Kallanthottathil G Rajeev, Muthiah Manoharan, Victor Koteliansky, Ingo Röhl, Elizaveta S Leshchiner, Robert Langer and Daniel G Anderson
Mol Ther 17: 872-879; advance online publication, March 3, 2009; doi:10.1038/mt.2009.36
Genetic Manipulation of Tumor-specific Cytotoxic T Lymphocytes to Restore Responsiveness to IL-7
Juan F Vera, Valentina Hoyos, Barbara Savoldo, Concetta Quintarelli, Greta MP Giordano Attianese, Ann M Leen, Hao Liu, Aaron E Foster, Helen E Heslop, Cliona M Rooney, Malcolm K Brenner and Gianpietro Dotti
Mol Ther 17: 880-888; advance online publication, March 3, 2009; doi:10.1038/mt.2009.34
Baculovirus Transduction of Mesenchymal Stem Cells: In Vitro Responses and In Vivo Immune Responses After Cell Transplantation
Ching-Kuang Chuang, Tong-Hong Wong, Shiaw-Min Hwang, Yu-Han Chang, Guan-Yu Chen, Yung-Chung Chiu, Shiu-Feng Huang and Yu-Chen Hu
Mol Ther 17: 889-896; advance online publication, March 10, 2009; doi:10.1038/mt.2009.30
Tolerance Induction in Experimental Autoimmune Encephalomyelitis Using Non-myeloablative Hematopoietic Gene Therapy With Autoantigen
Herena Eixarch, Carmen Espejo, Alba Gómez, María José Mansilla, Mireia Castillo, Alexander Mildner, Francisco Vidal, Ramón Gimeno, Marco Prinz, Xavier Montalban and Jordi Barquinero
Mol Ther 17: 897-905; advance online publication, March 10, 2009; doi:10.1038/mt.2009.42
Adoptive Transfer of Human Papillomavirus E7-specific CTL Enhances Tumor Chemoresponse Through the Perforin/Granzyme-mediated Pathway
Jeong-Im Sin, Jung-Min Kim, Sung Hwa Bae, In Hee Lee, Jong Sup Park and Hun Mo Ryoo
Mol Ther 17: 906-913; advance online publication, March 10, 2009; doi:10.1038/mt.2009.32
Local Gene Transfer and Expression Following Intramuscular Administration of FGF-1 Plasmid DNA in Patients With Critical Limb Ischemia
Iris Baumgartner, Nicolas Chronos, Anthony Comerota, Timothy Henry, Jean-Paul Pasquet, François Finiels, Anne Caron, Jean-François Dedieu, Richard Pilsudski and Pia Delaère
Mol Ther 17: 914-921; advance online publication, February 24, 2009; doi:10.1038/mt.2009.24
Tolerability of Two Sequential Electroporation Treatments Using MedPulser DNA Delivery System (DDS) in Healthy Adults
Mark Wallace, Barbara Evans, Sandra Woods, Robin Mogg, Lei Zhang, Adam C Finnefrock, Dietmar Rabussay, Michael Fons, John Mallee, Devan Mehrotra, Florian Schödel and Luwy Musey
Mol Ther 17: 922-928; advance online publication, March 10, 2009; doi:10.1038/mt.2009.27
