TABLE OF CONTENTS
Volume 16, Issue 4 (April 2008)
Editorial
Foamy Virus Vectors Come of Age FREE
David A Williams
Mol Ther 16: 635-636; doi:10.1038/mt.2008.34
In This Issue
In This Issue FREE
Mol Ther 16: 638; doi:10.1038/mt.2008.45
See also: Original Article by Chang et al. See also: Original Article by Rapoport et al. See also: Original Article by Weber et al. See also: Original Article by Nishina et al. See also: Original Article by Gonçalves et al.Research Highlights
Top of pageMeeting Report
Gene Delivery to the Nervous System FREE
Manfred Schubert, Xandra Breakefield, Howard Federoff, Robert M Frederickson and Pedro R Lowenstein
Mol Ther 16: 640-646; doi:10.1038/mt.2008.42
Commentary
TAT Opens the Door FREE
Piyush M Vyas and Ronald M Payne
Mol Ther 16: 647-648; doi:10.1038/mt.2008.24
Original Articles
Monogenic Disease
Intraventricular Enzyme Replacement Improves Disease Phenotypes in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis FREE
Michael Chang, Jonathan D Cooper, David E Sleat, Seng H Cheng, James C Dodge, Marco A Passini, Peter Lobel and Beverly L Davidson
Mol Ther 16: 649-656; advance online publication, February 12, 2008; doi:10.1038/mt.2008.9
Systemic Microdystrophin Gene Delivery Improves Skeletal Muscle Structure and Function in Old Dystrophic mdx Mice FREE
Paul Gregorevic, Michael J Blankinship, James M Allen and Jeffrey S Chamberlain
Mol Ther 16: 657-664; advance online publication, March 4, 2008; doi:10.1038/mt.2008.28
AAV Vector-mediated Reversal of Hypoglycemia in Canine and Murine Glycogen Storage Disease Type Ia FREE
Dwight D Koeberl, Carlos Pinto, Baodong Sun, Songtao Li, Daniel M Kozink, Daniel K Benjamin Jr., Amanda K Demaster, Meghan A Kruse, Valerie Vaughn, Steven Hillman, Andrew Bird, Mark Jackson, Talmage Brown, Priya S Kishnani and Yuan-Tsong Chen
Mol Ther 16: 665-672; advance online publication, March 11, 2008; doi:10.1038/mt.2008.15
Correction of Murine PKU Following AAV-mediated Intramuscular Expression of a Complete Phenylalanine Hydroxylating System FREE
Zhaobing Ding, Cary O Harding, Alexandre Rebuffat, Lina Elzaouk, Jon A Wolff and Beat Thöny
Mol Ther 16: 673-681; advance online publication, March 11, 2008; doi:10.1038/mt.2008.17
Acquired and Multigenic Disease
Flt3L in Combination With HSV1-TK-mediated Gene Therapy Reverses Brain Tumor–induced Behavioral Deficits FREE
Gwendalyn D King, Kurt M Kroeger, Catherine J Bresee, Marianela Candolfi, Chunyan Liu, Charlene M Manalo, AKM Ghulam Muhammad, Robert N Pechnick, Pedro R Lowenstein and Maria G Castro
Mol Ther 16: 682-690; advance online publication, February 19, 2008; doi:10.1038/mt.2008.18
Vector Engineering and Delivery
TAT-mediated Delivery of LAD Restores Pyruvate Dehydrogenase Complex Activity in the Mitochondria of Patients with LAD Deficiency FREE
Matan Rapoport, Ann Saada, Orly Elpeleg and Haya Lorberboum-Galski
Mol Ther 16: 691-697; advance online publication, February 5, 2008; doi:10.1038/mt.2008.4
A Multicolor Panel of Novel Lentiviral "Gene Ontology" (LeGO) Vectors for Functional Gene Analysis FREE
Kristoffer Weber, Udo Bartsch, Carol Stocking and Boris Fehse
Mol Ther 16: 698-706; advance online publication, February 12, 2008; doi:10.1038/mt.2008.6
Comparison of Zinc Finger Nucleases for Use in Gene Targeting in Mammalian Cells FREE
Shondra M Pruett-Miller, Jon P Connelly, Morgan L Maeder, J Keith Joung and Matthew H Porteus
Mol Ther 16: 707-717; advance online publication, March 4, 2008; doi:10.1038/mt.2008.20
Vector Toxicology, Immunogenicity and Safety
Physiological Promoters Reduce the Genotoxic Risk of Integrating Gene Vectors FREE
Daniela Zychlinski, Axel Schambach, Ute Modlich, Tobias Maetzig, Johann Meyer, Elke Grassman, Anjali Mishra and Christopher Baum
Mol Ther 16: 718-725; advance online publication, March 4, 2008; doi:10.1038/mt.2008.5
Transduction Properties of Adenovirus Serotype 35 Vectors After Intravenous Administration Into Nonhuman Primates FREE
Fuminori Sakurai, Shin-ichiro Nakamura, Kimiyo Akitomo, Hiroaki Shibata, Keiji Terao, Kenji Kawabata, Takao Hayakawa and Hiroyuki Mizuguchi
Mol Ther 16: 726-733; advance online publication, March 11, 2008; doi:10.1038/mt.2008.19
Oligonucleotide Therapy
Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of 
-Tocopherol FREE
Kazutaka Nishina, Toshinori Unno, Yoshitaka Uno, Takayuki Kubodera, Tadashi Kanouchi, Hidehiro Mizusawa and Takanori Yokota
Mol Ther 16: 734-740; advance online publication, February 12, 2008; doi:10.1038/mt.2008.14
Cell Therapy
Genetic Complementation of Human Muscle Cells via Directed Stem Cell Fusion FREE
Manuel AFV Gonçalves, Jim Swildens, Maarten Holkers, Anjali Narain, Gijsbert P van Nierop, Marloes JM van de Watering, Shoshan Knaän-Shanzer and Antoine AF de Vries
Mol Ther 16: 741-748; advance online publication, March 4, 2008; doi:10.1038/mt.2008.16
A Tumor-selective Biotherapy With Prolonged Impact on Established Metastases Based on Cytokine Gene-engineered MSCs FREE
Xiancheng Chen, Xiaojuan Lin, Jianlei Zhao, Wei Shi, Heng Zhang, Yongsheng Wang, Bing Kan, Licheng Du, Baiding Wang, Yuquan Wei, Yi Liu and Xia Zhao
Mol Ther 16: 749-756; advance online publication, February 5, 2008; doi:10.1038/mt.2008.3
Gene Therapy of 
c-Deficient Pulmonary Alveolar Proteinosis (c-PAP): Studies in a Murine in vivo Model FREE
Veronika Kleff, Ursula R Sorg, Carsten Bury, Takuji Suzuki, Ina Rattmann, Moran Jerabek-Willemsen, Christopher Poremba, Michael Flasshove, Bertram Opalka, Bruce Trapnell, Uta Dirksen and Thomas Moritz
Mol Ther 16: 757-764; advance online publication, March 4, 2008; doi:10.1038/mt.2008.7
A Comprehensive Platform for Ex Vivo T-cell Expansion Based on Biodegradable Polymeric Artificial Antigen-presenting Cells FREE
Erin R Steenblock and Tarek M Fahmy
Mol Ther 16: 765-772; advance online publication, March 4, 2008; doi:10.1038/mt.2008.11
Vaccine Technology
Mechanisms of Immunization Against Cancer Using Chimeric Antigens FREE
Manuel E Engelhorn, José A Guevara-Patiño, Taha Merghoub, Cailian Liu, Cristina R Ferrone, Gabriele A Rizzuto, Daniel H Cymerman, David N Posnett, Alan N Houghton and Jedd D Wolchok
Mol Ther 16: 773-781; advance online publication, February 26, 2008; doi:10.1038/mt.2008.8
Clinical Trials
Phase I Clinical Trial of Autologous Ascites-derived Exosomes Combined With GM-CSF for Colorectal Cancer FREE
Shengming Dai, Dong Wei, Zhen Wu, Xiangyang Zhou, Xiaomou Wei, Haixin Huang and Guisheng Li
Mol Ther 16: 782-790; advance online publication, February 5, 2008; doi:10.1038/mt.2008.1
Ranibizumab for Macular Edema Due to Retinal Vein Occlusions: Implication of VEGF as a Critical Stimulator FREE
Peter A Campochiaro, Gulnar Hafiz, Syed Mahmood Shah, Quan Dong Nguyen, Howard Ying, Diana V Do, Edward Quinlan, Ingrid Zimmer-Galler, Julia A Haller, Sharon D Solomon, Jennifer U Sung, Yasmin Hadi, Kashif A Janjua, Nida Jawed, David F Choy and Joseph R Arron
Mol Ther 16: 791-799; advance online publication, February 5, 2008; doi:10.1038/mt.2008.10
