TABLE OF CONTENTS
Volume 15, Issue 7 (July 2007)
In This Issue |
Research Highlights |
Meeting Report |
Reviews |
Original Articles |
Erratum
Editorials
NIH Decides Against Continuing NGVLs in Their Current Form FREE
David A Williams Editor-in-Chief
Mol Ther 15: 1223; doi:10.1038/sj.mt.6300226
Remodeling the NGVL Program to Meet Contemporary Needs FREE
Anthony R Hayward
Mol Ther 15: 1223-1224; doi:10.1038/sj.mt.6300229
In This Issue
In This Issue FREE
Mol Ther 15: 1226; doi:10.1038/sj.mt.6300237
See also: Original Article by Miletic et al. See also: Review by Rissanen & Ylä-HerttualaSee also: Original Article by Cardarelli et al. See also: Original Article by de Bruin et al. See also: Original Article by Riu et al.Research Highlights
Top of pageMeeting Report
Integrating Ideas on Insertional Mutagenesis by Gene Transfer Vectors FREE
Robert M Frederickson
Mol Ther 15: 1228-1232; doi:10.1038/sj.mt.6300234
Reviews
Acquired and Multigenic Disease
Current Status of Cardiovascular Gene Therapy FREE
Tuomas T Rissanen and Seppo Ylä-Herttuala
Mol Ther 15: 1233-1247; advance online publication, May 8, 2007; doi:10.1038/sj.mt.6300175
Cell Therapy
The Suicide Gene Therapy Challenge: How to Improve a Successful Gene Therapy Approach FREE
Chiara Bonini, Attilio Bondanza, Serena Kimi Perna, Shin Kaneko, Catia Traversari, Fabio Ciceri and Claudio Bordignon
Mol Ther 15: 1248-1252; advance online publication, May 8, 2007; doi:10.1038/sj.mt.6300190
Original Articles
Monogenic Disease
Efficacy of Helper-dependent Adenovirus Vector-mediated Gene Therapy in Murine Glycogen Storage Disease Type Ia FREE
Dwight D Koeberl, B Sun, A Bird, YT Chen, K Oka and L Chan
Mol Ther 15: 1253-1258; advance online publication, May 15, 2007; doi:10.1038/sj.mt.6300188
Acquired and Multigenic Disease
Role of Acid Ceramidase in Resistance to FasL: Therapeutic Approaches Based on Acid Ceramidase Inhibitors and FasL Gene Therapy FREE
Saeed Elojeimy, Xiang Liu, John C Mckillop, Ahmed M El-Zawahry, David H Holman, Jonathan Y Cheng, William D Meacham, Ayman EM Mahdy, Antonio F Saad, Lorianne S Turner, Joseph Cheng, Terrence A Day, Jian-Yun Dong, Alicja Bielawska, Yusuf A Hannun and James Scott Norris
Mol Ther 15: 1259-1263; advance online publication, April 10, 2007; doi:10.1038/sj.mt.6300167
Lentiviral Gene Delivery of vMIP-II to Transplanted Endothelial Cells and Endothelial Progenitors Is Proangiogenic In Vivo FREE
Stephanie Cherqui, Kenneth M Kingdon, Camille Thorpe, Sunil M Kurian and Daniel R Salomon
Mol Ther 15: 1264-1272; advance online publication, May 1, 2007; doi:10.1038/sj.mt.6300183
Vector Engineering and Delivery
Correction of DNA Protein Kinase Deficiency by Spliceosome-mediated RNA Trans-splicing and Sleeping Beauty Transposon Delivery FREE
Hatem Zayed, Lily Xia, Anton Yerich, Stephen R Yant, Mark A Kay, M Puttaraju, Gerard J McGarrity, David L Wiest, R Scott McIvor, Jakub Tolar and Bruce R Blazar
Mol Ther 15: 1273-1279; advance online publication, April 24, 2007; doi:10.1038/sj.mt.6300178
Messenger RNA as a Source of Transposase for Sleeping Beauty Transposon–mediated Correction of Hereditary Tyrosinemia Type I FREE
Andrew Wilber, Kirk J Wangensteen, Yixin Chen, Lijuan Zhuo, Joel L Frandsen, Jason B Bell, Zongyu J Chen, Stephen C Ekker, R Scott McIvor and Xin Wang
Mol Ther 15: 1280-1287; advance online publication, April 17, 2007; doi:10.1038/sj.mt.6300160
Antisense Oligonucleotide-induced Exon Skipping Across the Human Dystrophin Gene Transcript FREE
Steve D Wilton, Abbie M Fall, Penny L Harding, Graham McClorey, Catherine Coleman and Susan Fletcher
Mol Ther 15: 1288-1296; advance online publication, February 6, 2007; doi:10.1038/sj.mt.6300095
Cellular Dynamics of EGF Receptor–Targeted Synthetic Viruses FREE
Karla de Bruin, Nadia Ruthardt, Katharina von Gersdorff, Ralf Bausinger, Ernst Wagner, Manfred Ogris and Christoph Bräuchle
Mol Ther 15: 1297-1305; advance online publication, April 24, 2007; doi:10.1038/sj.mt.6300176
Rapid Optimization of Gene Delivery by Parallel End-modification of Poly(
-amino ester)s FREE
Gregory T Zugates, Weidan Peng, Andreas Zumbuehl, Siddharth Jhunjhunwala, Yu-Hung Huang, Robert Langer, Janet A Sawicki and Daniel G Anderson
Mol Ther 15: 1306-1312; advance online publication, March 20, 2007; doi:10.1038/sj.mt.6300132
In Vivo Study of HIV-1 Tat Arginine-rich Motif Unveils Its Transport Properties FREE
Francesco Cardarelli, Michela Serresi, Ranieri Bizzarri, Mauro Giacca and Fabio Beltram
Mol Ther 15: 1313-1322; advance online publication, May 1, 2007; doi:10.1038/sj.mt.6300172
A Dual Role of EGFR Protein Tyrosine Kinase Signaling in Ubiquitination of AAV2 Capsids and Viral Second-strand DNA Synthesis FREE
Li Zhong, Weihong Zhao, Jianqing Wu, Baozheng Li, Sergei Zolotukhin, Lakshmanan Govindasamy, Mavis Agbandje-McKenna and Arun Srivastava
Mol Ther 15: 1323-1330; advance online publication, April 17, 2007; doi:10.1038/sj.mt.6300170
Lentiviral Vectors Mediate Stable and Efficient Gene Delivery into Primary Murine Natural Killer Cells FREE
Jimmy Tran and Sam KP Kung
Mol Ther 15: 1331-1339; advance online publication, May 8, 2007; doi:10.1038/sj.mt.6300184
Development and Validation of a Robust and Versatile One-plasmid Regulated Gene Expression System FREE
Paul Szymanski, Peter J Kretschmer, Maxine Bauzon, Fang Jin, Hu Sheng Qian, Gabor M Rubanyi, Richard N Harkins and Terry W Hermiston
Mol Ther 15: 1340-1347; advance online publication, May 1, 2007; doi:10.1038/sj.mt.6300171
Vector Toxicology, Immunogenicity and Safety
Histone Modifications are Associated with the Persistence or Silencing of Vector-mediated Transgene Expression In Vivo FREE
Efren Riu, Zhi-Ying Chen, Hui Xu, Chen-Yi He and Mark A Kay
Mol Ther 15: 1348-1355; advance online publication, April 24, 2007; doi:10.1038/sj.mt.6300177
Comparison of HIV-derived Lentiviral and MLV-based Gammaretroviral Vector Integration Sites in Primate Repopulating Cells FREE
Brian C Beard, David Dickerson, Kate Beebe, Christina Gooch, James Fletcher, Tulin Okbinoglu, Daniel G Miller, Michael A Jacobs, Rajinder Kaul, Hans-Peter Kiem and Grant D Trobridge
Mol Ther 15: 1356-1365; advance online publication, April 17, 2007; doi:10.1038/sj.mt.6300159
A High Throughput In Vivo Model for Testing Delivery and Antiviral Effects of siRNAs in Vertebrates FREE
Brian Dall Schyth, Niels Lorenzen and Finn Skou Pedersen
Mol Ther 15: 1366-1372; advance online publication, May 1, 2007; doi:10.1038/sj.mt.6300150
Cell Therapy
Bystander Killing of Malignant Glioma by Bone Marrow–derived Tumor-Infiltrating Progenitor Cells Expressing a Suicide Gene FREE
Hrvoje Miletic, Yvonne Fischer, Sara Litwak, Tsanan Giroglou, Yannic Waerzeggers, Alexandra Winkeler, Huongfeng Li, Uwe Himmelreich, Claudia Lange, Werner Stenzel, Martina Deckert, Harald Neumann, Andreas H Jacobs and Dorothee von Laer
Mol Ther 15: 1373-1381; advance online publication, April 24, 2007; doi:10.1038/sj.mt.6300155
Mesenchymal Stem Cells Over-expressing Hepatocyte Growth Factor Improve Small-for-size Liver Grafts Regeneration FREE
Yue Yu, Ai-Hua Yao, Nian Chen, Li-Yong Pu, Ye Fan, Ling Lv, Bei-Cheng Sun, Guo-Qiang Li and Xue-Hao Wang
Mol Ther 15: 1382-1389; advance online publication, May 22, 2007; doi:10.1038/sj.mt.6300202
Vaccine Technology
Lentiviral Vectors with CMV or MHCII Promoters Administered In Vivo: Immune Reactivity Versus Persistence of Expression FREE
Takahiro Kimura, Richard C Koya, Laura Anselmi, Catia Sternini, He-Jing Wang, Begonya Comin-Anduix, Robert M Prins, Emmanuelle Faure-Kumar, Nora Rozengurt, Yan Cui, Noriyuki Kasahara and Renata Stripecke
Mol Ther 15: 1390-1399; advance online publication, May 1, 2007; doi:10.1038/sj.mt.6300180
