TABLE OF CONTENTS
Volume 15, Issue 5 (May 2007)
Editorial
Shedding Light on Tumor Targeting by Adenovirus FREE
Andrew H Baker Associate Editor
Mol Ther 15: 841-842; doi:10.1038/sj.mt.6300158
See also: Original Article by Mocanu et al.In This Issue
In This Issue FREE
Mol Ther 15: 844; doi:10.1038/sj.mt.6300173
See also: Original Article by Aagaard et al. See also: Original Article by Lu & GhazizadehSee also: Original Article by Perrin et al. See also: Original Article by Nguyen et al. See also: Original Article by Yang et al.Research Highlights
Top of pageCommentaries
Programming the Next Generation of Dendritic Cells FREE
Richard G Carroll and Carl H June
Mol Ther 15: 846-848; doi:10.1038/sj.mt.6300166
See also: Original Article by Koya et al.I Could Die for You: New Prospects for Suicide in Gene Therapy FREE
Christopher Baum
Mol Ther 15: 848-849; doi:10.1038/sj.mt.6300164
See also: Original Article by Sato et al.Reviews
Cell Therapy
Human Embryonic Stem Cells and Gene Therapy FREE
Yael Strulovici, Philip L Leopold, Timothy P O'Connor, Robert G Pergolizzi and Ronald G Crystal
Mol Ther 15: 850-866; advance online publication, March 20, 2007; doi:10.1038/mt.sj.6300125
Stem and Progenitor Cells in Skeletal Muscle Development, Maintenance, and Therapy FREE
Bruno Péault, Michael Rudnicki, Yvan Torrente, Giulio Cossu, Jacques P Tremblay, Terry Partridge, Emanuela Gussoni, Louis M Kunkel and Johnny Huard
Mol Ther 15: 867-877; advance online publication, March 27, 2007; doi:10.1038/mt.sj.6300145
Vector Engineering and Delivery
Combinatorial RNAi: A Winning Strategy for the Race Against Evolving Targets? FREE
Dirk Grimm and Mark A Kay
Mol Ther 15: 878-888; advance online publication, February 20, 2007; doi:10.1038/sj.mt.6300116
Original Articles
Monogenic Disease
Improvements in Mucopolysaccharidosis I Mice After Adult Retroviral Vector–mediated Gene Therapy with Immunomodulation FREE
Xiucui Ma, Yuli Liu, Mindy Tittiger, Anne Hennig, Attila Kovacs, Sarah Popelka, Baomei Wang, Ramin Herati, Mark Bigg and Katherine P Ponder
Mol Ther 15: 889-902; advance online publication, February 20, 2007; doi:10.1038/sj.mt.6300112
Acquired and Multigenic Disease
Neuroprotection by Hsp104 and Hsp27 in Lentiviral-based Rat Models of Huntington's Disease FREE
Valérie Perrin, Etienne Régulier, Toufik Abbas-Terki, Raymonde Hassig, Emmanuel Brouillet, Patrick Aebischer, Ruth Luthi-Carter and Nicole Déglon
Mol Ther 15: 903-911; advance online publication, March 20, 2007; doi:10.1038/mt.sj.6300141
Vector Engineering and Delivery
Rapamycin-regulated Control of Antiangiogenic Tumor Therapy Following rAAV-mediated Gene Transfer FREE
Minh Nguyen, Guang Huan-Tu, Melissa Gonzalez-Edick, Victor M Rivera, Tim Clackson, Karin U Jooss and Thomas C Harding
Mol Ther 15: 912-920; advance online publication, January 23, 2007; doi:10.1038/mt.sj.6300079
Imaging the Modulation of Adenoviral Kinetics and Biodistribution for Cancer Gene Therapy FREE
Joseph D Mocanu, Kenneth W Yip, Nehad M Alajez, Wei Shi, Jian-Hua Li, Sarah J Lunt, Eduardo H Moriyama, Brian C Wilson, Michael Milosevic, Kwok-Wai Lo, Nico van van Rooijen, Pierre Busson, Carlo Bastianutto and Fei-Fei Liu
Mol Ther 15: 921-929; advance online publication, March 13, 2007; doi:10.1038/mt.sj.6300119
See also: Editorial by BakerEfficient Transduction of Simian Cells by HIV-1-based Lentiviral Vectors that Contain Mutations in the Capsid Protein FREE
Maarten AN Rits, Karel A van Dort, Carsten Münk, Alexander B Meijer and Neeltje A Kootstra
Mol Ther 15: 930-937; advance online publication, February 13, 2007; doi:10.1038/mt.sj.6300091
A Facile Lentiviral Vector System for Expression of Doxycycline-Inducible shRNAs: Knockdown of the Pre-miRNA Processing Enzyme Drosha FREE
Lars Aagaard, Mohammed Amarzguioui, Guihua Sun, Luis C Santos, Ali Ehsani, Hans Prydz and John J Rossi
Mol Ther 15: 938-945; advance online publication, February 20, 2007; doi:10.1038/sj.mt.6300118
Adhesion Receptors Mediate Efficient Non-viral Gene Delivery FREE
Inge S Zuhorn, Dharamdajal Kalicharan, George T Robillard and Dick Hoekstra
Mol Ther 15: 946-953; advance online publication, March 20, 2007; doi:10.1038/mt.sj.6300139
Vector Toxicology, Immunogenicity and Safety
Loss of Transgene following ex vivo Gene Transfer is Associated with a Dominant Th2 Response: Implications for Cutaneous Gene Therapy FREE
Zhenmei Lu and Soosan Ghazizadeh
Mol Ther 15: 954-961; advance online publication, March 13, 2007; doi:10.1038/mt.sj.6300086
Engineered Human tmpk/AZT As a Novel Enzyme/Prodrug Axis for Suicide Gene Therapy FREE
Takeya Sato, Anton Neschadim, Manfred Konrad, Daniel H Fowler, Arnon Lavie and Jeffrey A Medin
Mol Ther 15: 962-970; advance online publication, March 20, 2007; doi:10.1038/mt.sj.6300122
See also: Commentary by BaumCell Therapy
Lentiviral Vector–mediated Autonomous Differentiation of Mouse Bone Marrow Cells into Immunologically Potent Dendritic Cell Vaccines FREE
Richard C Koya, Takahiro Kimura, Antoni Ribas, Nora Rozengurt, Gregory W Lawson, Emmanuelle Faure-Kumar, He-jing Wang, Harvey Herschman, Noriyuki Kasahara and Renata Stripecke
Mol Ther 15: 971-980; advance online publication, March 20, 2007; doi:10.1038/mt.sj.6300126
Abstract | Full Text | PDF | Supplementary information
See also: Commentary by Carroll & JuneEngineering Artificial Antigen-presenting Cells to Express a Diverse Array of Co-stimulatory Molecules FREE
Megan M Suhoski, Tatiana N Golovina, Nicole A Aqui, Victoria C Tai, Angel Varela-Rohena, Michael C Milone, Richard G Carroll, James L Riley and Carl H June
Mol Ther 15: 981-988; advance online publication, March 20, 2007; doi:10.1038/mt.sj.6300134
Vaccine Technology
Avian Influenza Virus Hemagglutinin Display on Baculovirus Envelope: Cytoplasmic Domain Affects Virus Properties and Vaccine Potential FREE
Ding-Gang Yang, Yao-Chi Chung, Yiu-Kay Lai, Chia-Wei Lai, Hung-Jen Liu and Yu-Chen Hu
Mol Ther 15: 989-996; advance online publication, March 20, 2007; doi:10.1038/mt.sj.6300131
On the Role of CD4+ T Cells in the CD8+ T-Cell Response Elicited by Recombinant Adenovirus Vaccines FREE
Teng Chih Yang, James Millar, Timothy Groves, Wenzhong Zhou, Natalie Grinshtein, Robin Parsons, Carole Evelegh, Zhou Xing, Yonghong Wan and Jonathan Bramson
Mol Ther 15: 997-1006; advance online publication, March 20, 2007; doi:10.1038/sj.mt.6300130
Effects of MIP-1
, MIP-3, and MIP-3
on the Induction of HIV Gag-specific Immune Response with DNA Vaccines FREE
Ruijiang Song, Shuqin Liu and Kam W Leong
Mol Ther 15: 1007-1015; advance online publication, March 13, 2007; doi:10.1038/mt.sj.6300129
Clinical Trials
Phase I Trial of Replication-competent Adenovirus-mediated Suicide Gene Therapy Combined with IMRT for Prostate Cancer FREE
Svend O Freytag, Benjamin Movsas, Ibrahim Aref, Hans Stricker, James Peabody, Jan Pegg, Yingshu Zhang, Kenneth N Barton, Stephen L Brown, Mei Lu, Adnan Savera and Jae Ho Kim
Mol Ther 15: 1016-1023; advance online publication, March 20, 2007; doi:10.1038/mt.sj.6300120
Transfer of Autologous Gene-modified T Cells in HIV-infected Patients with Advanced Immunodeficiency and Drug-resistant Virus FREE
Jan van Lunzen, Tobias Glaunsinger, Ingrid Stahmer, Volker von Baehr, Christopher Baum, Andrea Schilz, Klaus Kuehlcke, Sonja Naundorf, Holger Martinius, Felix Hermann, Tsanan Giroglou, Sebastian Newrzela, Ingrid Müller, Francis Brauer, Gunda Brandenburg, Alexander Alexandrov and Dorothee von Laer
Mol Ther 15: 1024-1033; advance online publication, March 13, 2007; doi:10.1038/mt.sj.6300124
