TABLE OF CONTENTS
Volume 15, Issue 11 (November 2007)
In This Issue |
Research Highlights |
Commentary |
Review |
Original Articles |
Corrigenda
Editorial
A New Serious Adverse Event in a Gene Therapy Study FREE
Theodore Friedmann
Mol Ther 15: 1899-1900; doi:10.1038/sj.mt.6300328
In This Issue
In This Issue FREE
Mol Ther 15: 1902; doi:10.1038/sj.mt.6300327
See also: Original Article by Yokoi et al. See also: Original Article by Tan et al. See also: Original Article by Apolonia et al. See also: Commentary by Hu et al. See also: Original Article by Pariente et al. See also: Commentary by MummerySee also: Original Article by Anderson et al.Research Highlights
Top of pageCommentary
Stable Ethics: Enrolling Non-Treatment-Refractory Volunteers in Novel Gene Transfer Trials FREE
Jonathan Kimmelman
Mol Ther 15: 1904-1906; doi:10.1038/sj.mt.6300316
A Dual-Targeted Lentiviral Vector Homing in on Prostate Bone Metastases FREE
Yufang Hu, David Stout and Lily Wu
Mol Ther 15: 1906-1908; doi:10.1038/sj.mt.6300317
See also: Original Article by Pariente et al.Genetic Selection of Cardiomyocytes from Human Embryonic Stem Cells FREE
Christine Mummery
Mol Ther 15: 1908-1909; doi:10.1038/sj.mt.6300307
See also: Original Article by Anderson et al.Review
Vector Toxicology, Immunogenicity and Safety
New Insights and Unresolved Issues Regarding Insertional Mutagenesis in X-linked SCID Gene Therapy FREE
Karin Pike-Overzet, Mirjam van der Burg, Gerard Wagemaker, Jacques JM van Dongen and Frank JT Staal
Mol Ther 15: 1910-1916; advance online publication, August 28, 2007; doi:10.1038/sj.mt.6300297
Original Articles
Acquired and Multigenic Disease
Gene Transfer of An Engineered Zinc Finger Protein Enhances the Anti-angiogenic Defense System FREE
Katsutoshi Yokoi, Huanda Steve Zhang, Shu Kachi, Kamaljit S Balaggan, Qi Yu, Dmitry Guschin, Mike Kunis, Richard Surosky, Liza M Africa, James W Bainbridge, Sharon Kaye Spratt, Philip D Gregory, Robin R Ali and Peter A Campochiaro
Mol Ther 15: 1917-1923; advance online publication, August 14, 2007; doi:10.1038/sj.mt.6300280
Vegf or EphA2 Antisense Polyamide-nucleic acids; Vascular Localization and Suppression of Retinal Neovascularization FREE
Jikui Shen, Bing Xie, Christina M Hatara, Sean F Hackett and Peter A Campochiaro
Mol Ther 15: 1924-1930; advance online publication, August 7, 2007; doi:10.1038/sj.mt.6300276
Inhibition of Enterovirus 71 in Virus-infected Mice by RNA Interference FREE
Eng Lee Tan, Theresa May Chin Tan, Vincent Tak Kwong Chow and Chit Laa Poh
Mol Ther 15: 1931-1938; advance online publication, August 21, 2007; doi:10.1038/sj.mt.6300287
Urokinase Gene Transfer Augments Angiogenesis in Ischemic Skeletal and Myocardial Muscle FREE
Dmitry O Traktuev, Zoya I Tsokolaeva, Alexander A Shevelev, Konstantin A Talitskiy, Victoria V Stepanova, Brian H Johnstone, Tahmina M Rahmat-Zade, Alexander N Kapustin, Vsevolod A Tkachuk, Keith L March and Yelena V Parfyonova
Mol Ther 15: 1939-1946; advance online publication, July 24, 2007; doi:10.1038/sj.mt.6300262
Vector Engineering and Delivery
Stable Gene Transfer to Muscle Using Non-integrating Lentiviral Vectors FREE
Luis Apolonia, Simon N Waddington, Carolina Fernandes, Natalie J Ward, Gerben Bouma, Michael P Blundell, Adrian J Thrasher, Mary K Collins and Nicola J Philpott
Mol Ther 15: 1947-1954; advance online publication, August 14, 2007; doi:10.1038/sj.mt.6300281
Characterization of the Relationship of AAV Capsid Domain Swapping to Liver Transduction Efficiency FREE
Xuan Shen, Terry Storm and Mark A Kay
Mol Ther 15: 1955-1962; advance online publication, August 28, 2007; doi:10.1038/sj.mt.6300293
Intracellular Trafficking of a Fiber-modified Adenovirus Using Lipid Raft/Caveolae Endocytosis FREE
Sophie Rogée, Elodie Grellier, Claudine Bernard, Anne Loyens, Jean-Claude Beauvillain, Jean-Claude D'halluin and Morvane Colin
Mol Ther 15: 1963-1972; advance online publication, August 21, 2007; doi:10.1038/sj.mt.6300283
A Novel Dual-targeted Lentiviral Vector Leads to Specific Transduction of Prostate Cancer Bone Metastases In Vivo After Systemic Administration FREE
Nonia Pariente, Kouki Morizono, Mandeep S Virk, Frank A Petrigliano, Robert E Reiter, Jay R Lieberman and Irvin SY Chen
Mol Ther 15: 1973-1981; advance online publication, July 24, 2007; doi:10.1038/sj.mt.6300271
Abstract | Full Text | PDF | Supplementary information
See also: Commentary by Hu et al.Human Matrix Metalloproteinase-8 Gene Delivery Increases the Oncolytic Activity of a Replicating Adenovirus FREE
Jin Cheng, Harald Sauthoff, YaoQi Huang, David I Kutler, Sofia Bajwa, William N Rom and John G Hay
Mol Ther 15: 1982-1990; advance online publication, July 24, 2007; doi:10.1038/sj.mt.6300264
Vector Toxicology, Immunogenicity and Safety
An Immunocompetent Murine Model for Oncolysis with an Armed and Targeted Measles Virus FREE
Guy Ungerechts, Christoph Springfeld, Marie E Frenzke, Johanna Lampe, William B Parker, Eric J Sorscher and Roberto Cattaneo
Mol Ther 15: 1991-1997; advance online publication, August 21, 2007; doi:10.1038/sj.mt.6300291
Interactions Between Human Plasma Components and A Xenogenic Adenovirus Vector: Reduced Immunogenicity During Gene Transfer FREE
Matthieu Perreau, Marie-Christine Guérin, Christian Drouet and Eric J Kremer
Mol Ther 15: 1998-2007; advance online publication, August 21, 2007; doi:10.1038/sj.mt.6300289
Toxicity of Fiber- and Penton Base–modified Adenovirus Type 5 Vectors on Lung Development in Newborn Rats FREE
Paul Waszak, Laure Franqueville, Marie-Laure Franco-Motoya, Manuel Rosa-Calatrava, Olivier Boucherat, Leif Lindholm, Christophe Delacourt and Pierre Boulanger
Mol Ther 15: 2008-2016; advance online publication, July 24, 2007; doi:10.1038/sj.mt.6300254
Early STAT1 Activation After Systemic Delivery of HSV Amplicon Vectors Suppresses Transcription of The Vector-encoded Transgene FREE
Masataka Suzuki, E Antonio Chiocca and Yoshinaga Saeki
Mol Ther 15: 2017-2026; advance online publication, July 24, 2007; doi:10.1038/sj.mt.6300273
Cell Therapy
Transgenic Enrichment of Cardiomyocytes From Human Embryonic Stem Cells FREE
David Anderson, Tim Self, Ian R Mellor, Gareth Goh, Stephen J Hill and Chris Denning
Mol Ther 15: 2027-2036; advance online publication, September 25, 2007; doi:10.1038/sj.mt.6300303
Abstract | Full Text | PDF | Supplementary information
See also: Commentary by MummeryVaccine Technology
Immunization by Application of DNA Vaccine onto a Skin Area Wherein the Hair Follicles Have Been Induced into Anagen-onset Stage FREE
Dalia S Shaker, Brian R Sloat, Uyen M Le, Christiane V Löhr, Nijaporn Yanasarn, Kay A Fischer and Zhengrong Cui
Mol Ther 15: 2037-2043; advance online publication, August 14, 2007; doi:10.1038/sj.mt.6300286
Clinical Trials
Safety and Immunogenicity of Tyrosinase DNA Vaccines in Patients with Melanoma FREE
Jedd D Wolchok, Jianda Yuan, Alan N Houghton, Humilidad F Gallardo, Teresa S Rasalan, Jian Wang, Yan Zhang, Rajaram Ranganathan, Paul B Chapman, Susan E Krown, Philip O Livingston, Melanie Heywood, Isabelle Riviere, Katherine S Panageas, Stephanie L Terzulli and Miguel A Perales
Mol Ther 15: 2044-2050; advance online publication, August 28, 2007; doi:10.1038/sj.mt.6300290
Corrigenda
Corrigendum to "Efficacy of Helper-dependent Adenovirus Vector-mediated Gene Therapy in Murine Glycogen Storage Disease Type Ia" FREE
Dwight D Koeberl, Baodong Sun, Andrew Bird, Yuan-Tsong Chen, Kazuhiro Oka and Lawrence Chan
Mol Ther 15: 2051; doi:10.1038/sj.mt.6300269
