TABLE OF CONTENTS

Volume 15, Issue 10 (October 2007)

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Editorial

AAV and Insertional Mutagenesis FREE

David A Williams Editor-in-Chief

Mol Ther 15: 1737; doi:10.1038/sj.mt.6300301

See also: Commentary by Russell
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In This Issue

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Research Highlights

Research Highlights FREE

Mol Ther 15: 1739; doi:10.1038/sj.mt.6300312

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Commentary

AAV Vectors, Insertional Mutagenesis, and Cancer FREE

David W Russell

Mol Ther 15: 1740-1743; doi:10.1038/sj.mt.6300299

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Reviews

Cell Therapy

Monoclonal T-Cell Receptors: New Reagents for Cancer Therapy FREE

Hans J Stauss, Michela Cesco-Gaspere, Sharyn Thomas, Daniel P Hart, Shao-An Xue, Angelika Holler, Graham Wright, Mario Perro, Ann-Margaret Little, Constantina Pospori, Judy King and Emma C Morris

Mol Ther 15: 1744-1750; advance online publication, July 17, 2007; doi:10.1038/sj.mt.6300216

Vector Toxicology, Immunogenicity and Safety

Potential Use of Gene Transfer in Athletic Performance Enhancement FREE

Anna Baoutina, Ian E Alexander, John EJ Rasko and Kerry R Emslie

Mol Ther 15: 1751-1766; advance online publication, August 7, 2007; doi:10.1038/sj.mt.6300278

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Original Articles

Monogenic Disease

Successful Compensation for Dystrophin Deficiency by a Helper-dependent Adenovirus Expressing Full-length Utrophin FREE

Jatinderpal R Deol, Gawiyou Danialou, Nancy Larochelle, Mylène Bourget, Joon-Shik Moon, An-Bang Liu, Rénald Gilbert, Basil J Petrof, Josephine Nalbantoglu and George Karpati

Mol Ther 15: 1767-1774; advance online publication, July 31, 2007; doi:10.1038/sj.mt.6300260

Long-term Skeletal Muscle Protection After Gene Transfer in a Mouse Model of LGMD-2D FREE

Christina A Pacak, Glenn A Walter, Gabe Gaidosh, Nathan Bryant, Melissa A Lewis, Sean Germain, Cathryn S Mah, Kevin P Campbell and Barry J Byrne

Mol Ther 15: 1775-1781; advance online publication, July 24, 2007; doi:10.1038/sj.mt.6300246

Timing of Therapeutic Intervention Determines Functional and Survival Outcomes in a Mouse Model of Late Infantile Batten Disease FREE

Mario A Cabrera-Salazar, Eric M Roskelley, Jie Bu, Bradley L Hodges, Nelson Yew, James C Dodge, Lamya S Shihabuddin, Istvan Sohar, David E Sleat, Ronald K Scheule, Beverly L Davidson, Seng H Cheng, Peter Lobel and Marco A Passini

Mol Ther 15: 1782-1788; advance online publication, July 17, 2007; doi:10.1038/sj.mt.6300249

Correction in Female PKU Mice by Repeated Administration of mPAH cDNA Using phiBT1 Integration System FREE

Li Chen and Savio LC Woo

Mol Ther 15: 1789-1795; advance online publication, July 17, 2007; doi:10.1038/sj.mt.6300257

Acquired and Multigenic Disease

Lentiviral-mediated Expression of Polysialic Acid in Spinal Cord and Conditioning Lesion Promote Regeneration of Sensory Axons Into Spinal Cord FREE

Yi Zhang, Xinyu Zhang, Dongsheng Wu, Joost Verhaagen, Peter M Richardson, John Yeh and Xuenong Bo

Mol Ther 15: 1796-1804; advance online publication, June 5, 2007; doi:10.1038/sj.mt.6300220

Systemic Cancer Gene Therapy Using Adeno-associated Virus Type 1 Vector Expressing MDA-7/IL24 FREE

Ichiro Tahara, Koichi Miyake, Hideki Hanawa, Toshiyuki Kurai, Yukihiko Hirai, Masamichi Ishizaki, Eiji Uchida, Takashi Tajiri and Takashi Shimada

Mol Ther 15: 1805-1811; advance online publication, June 5, 2007; doi:10.1038/sj.mt.6300225

Treatment of Inflamed Pancreas with Enkephalin Encoding HSV-1 Recombinant Vector Reduces Inflammatory Damage and Behavioral Sequelae FREE

Ying Lu, Terry A McNearney, Weidong Lin, Steven P Wilson, David C Yeomans and Karin N Westlund

Mol Ther 15: 1812-1819; advance online publication, June 12, 2007; doi:10.1038/sj.mt.6300228

Vector Engineering and Delivery

A Novel Cell-penetrating Peptide, M918, for Efficient Delivery of Proteins and Peptide Nucleic Acids FREE

Samir El-Andaloussi, Henrik J Johansson, Tina Holm and Ülo Langel

Mol Ther 15: 1820-1826; advance online publication, July 10, 2007; doi:10.1038/sj.mt.6300255

Transduction of Human Embryonic Stem Cells by Foamy Virus Vectors FREE

Helen Gharwan, Roli K Hirata, Peirong Wang, Robert E Richard, Linlin Wang, Erik Olson, James Allen, Carol B Ware and David W Russell

Mol Ther 15: 1827-1833; advance online publication, July 10, 2007; doi:10.1038/sj.mt.6300244

Recombinant Human Foamy Virus, a Novel Vector for Neurological Disorders Gene Therapy, Drives Production of GAD in Cultured Astrocytes FREE

Wanhong Liu, Zhongchun Liu, Xiongbin Cao, Zhijian Cao, Lu Xue, Fan Zhu, Xiaohua He and Wenxin Li

Mol Ther 15: 1834-1841; advance online publication, June 19, 2007; doi:10.1038/sj.mt.6300224

Sine-wave Current for Efficient and Safe In Vivo Gene Transfer FREE

Feng Liu, Demet Sag, Jue Wang, Lisa M Shollenberger, Feilong Niu, Xing Yuan, Shyh-Dar Li, Mike Thompson and Paul Monahan

Mol Ther 15: 1842-1847; advance online publication, July 17, 2007; doi:10.1038/sj.mt.6300261

Neuronal Specificity of HSV/Sleeping Beauty Amplicon Transduction In Utero Is Driven Primarily by Tropism and Cell Type Composition FREE

Elise B Peterson, Michael A Mastrangelo, Howard J Federoff and William J Bowers

Mol Ther 15: 1848-1855; advance online publication, July 24, 2007; doi:10.1038/sj.mt.6300267

The Enhancing Effects of the Light Chain on Heavy Chain Secretion in Split Delivery of Factor VIII Gene FREE

Lingxia Chen, Fuxiang Zhu, Juan Li, Hui Lu, Haiyan Jiang, Rita Sarkar, Valder R Arruda, Jinhui Wang, Jennifer Zhao, Glenn F Pierce, Qiulan Ding, Xuefeng Wang, Hongli Wang, Steven W Pipe, Xiang-Qin Liu, Xiao Xiao, Rodney M Camire and Weidong Xiao

Mol Ther 15: 1856-1862; advance online publication, July 24, 2007; doi:10.1038/sj.mt.6300268

Vector Toxicology, Immunogenicity and Safety

Improved Human beta-globin Expression from Self-inactivating Lentiviral Vectors Carrying the Chicken Hypersensitive Site-4 (cHS4) Insulator Element FREE

Paritha I Arumugam, Jessica Scholes, Natalya Perelman, Ping Xia, Jiing-Kuan Yee and Punam Malik

Mol Ther 15: 1863-1871; advance online publication, July 10, 2007; doi:10.1038/sj.mt.6300259

Cell Therapy

A Study of the Role of Nell-1 Gene Modified Goat Bone Marrow Stromal Cells in Promoting New Bone Formation FREE

Tara Aghaloo, Xinquan Jiang, Chia Soo, Zhiyuan Zhang, Xiuli Zhang, Jingzhou Hu, Hongya Pan, Tiffany Hsu, Benjamin Wu, Kang Ting and Xinli Zhang

Mol Ther 15: 1872-1880; advance online publication, July 24, 2007; doi:10.1038/sj.mt.6300270

Sca-1+ Hematopoietic Cell–based Gene Therapy with a Modified FGF-2 Increased Endosteal/Trabecular Bone Formation in Mice FREE

Susan L Hall, Kin-Hing William Lau, Shin-Tai Chen, Jon E Wergedal, Apurva Srivastava, Henry Klamut, Matilda H-C Sheng, Daila S Gridley, Subburaman Mohan and David J Baylink

Mol Ther 15: 1881-1889; advance online publication, July 17, 2007; doi:10.1038/sj.mt.6300258

Vaccine Technology

IL-6-Encoding Tumor Antigen Generates Potent Cancer Immunotherapy Through Antigen Processing and Anti-apoptotic Pathways FREE

Chang-Yao Hsieh, Chi-An Chen, Chia-Yen Huang, Ming-Cheng Chang, Chien-Nan Lee, Yi-Ning Su and Wen-Fang Cheng

Mol Ther 15: 1890-1897; advance online publication, July 3, 2007; doi:10.1038/sj.mt.6300243

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