Molecular Therapy

FIGURE 4

FROM:

Adenovirus-based Prime-boost Immunization for Rapid Vaccination Against Anthrax

Michael J McConnell, Philip C Hanna and Michael J Imperiale

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Figure 4.

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In vitro toxin neutralization and protection from spore challenge. (a) LeTx-neutralizing titers of sera from mice taken 2 weeks after boosting. Bars represent the average value for each group with error bars representing the SEM (n=10/group). (b) Nineteen days after boosting mice were challenged with 8.1 times 104 Sterne 34F2 spores (73.5 times LD50) by subcutaneous injection and monitored for survival over 14 days (n=7/group).

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