FIGURE 6
FROM:
Central Nervous System-directed AAV2/5-Mediated Gene Therapy Synergizes with Bone Marrow Transplantation in the Murine Model of Globoid-cell Leukodystrophy
Darshong Lin, Anthony Donsante, Shannon Macauley, Beth Levy, Carole Vogler and Mark S Sands
BACK TO ARTICLEFigure 6.
Life span. The mean lifespans of untreated (Twi, bold solid/dotted line, n=14), BMT-treated (BMT, bold dotted line, n=15), AAV2/5-treated (AAV2/5, bold dashed line, n=15), and combination-treated (CmTx, bold solid line, n=17) Twitcher mice are 39, 44, 49, and 104 days, respectively. Fifty percent of the combination-treated animals were still alive at 111 days of age. No untreated normal (WT, fine solid line, n=12) or normal mice that received radiation alone (data not shown, n=4) died during the study.
