TABLE OF CONTENTS
Volume 14, Issue 1 (July 2006)
Editorial
Vector-related Tumorigenesis Not Found in Ornithine Transcarbamylase-deficient Mice
Dwight D. Koeberl
Mol Ther 14: 1-2; doi:10.1016/j.ymthe.2006.05.011
Inside this Month
Top of pageResearch Update
Top of pageOriginal Articles
Mucopolysaccharidosis I Cats Mount a Cytotoxic T Lymphocyte Response after Neonatal Gene Therapy That Can Be Blocked with CTLA4-Ig
Katherine P. Ponder, Baomei Wang, Ping Wang, Xiucui Ma, Ramin Herati, Bin Wang, Karyn Cullen, Patty O'Donnell, N. Matthew Ellinwood, Anne Traas, Tina M. Primeau and Mark E. Haskins
Mol Ther 14: 5-13; doi:10.1016/j.ymthe.2006.03.015
Genetic Correction of the Fetal Brain Increases the Lifespan of Mice with the Severe Multisystemic Disease Mucopolysaccharidosis Type VII
Brian A. Karolewski and John H. Wolfe
Mol Ther 14: 14-24; doi:10.1016/j.ymthe.2006.02.012
Long-Term Correction of Ammonia Metabolism and Prolonged Survival in Ornithine Transcarbamylase-Deficient Mice Following Liver-Directed Treatment with Adeno-associated Viral Vectors
David Moscioni, Hiroki Morizono, Robert J. McCarter, Adam Stern, Juan Cabrera-Luque, Albert Hoang, Julio Sanmiguel, Di Wu, Peter Bell, Guang-Ping Gao, Steven E. Raper, James M. Wilson and Mark L. Batshaw
Mol Ther 14: 25-33; doi:10.1016/j.ymthe.2006.03.009
Analysis of Tumors Arising in Male B6C3F1 Mice with and without AAV Vector Delivery to Liver
Peter Bell, A. David Moscioni, Robert J. McCarter, Di Wu, Guangping Gao, Albert Hoang, Julio C. Sanmiguel, Xun Sun, Nelson A. Wivel, Steven E. Raper, Emma E. Furth, Mark L. Batshaw and James M. Wilson
Mol Ther 14: 34-44; doi:10.1016/j.ymthe.2006.03.008
Robust Systemic Transduction with AAV9 Vectors in Mice: Efficient Global Cardiac Gene Transfer Superior to That of AAV8
Katsuya Inagaki, Sally Fuess, Theresa A. Storm, Gregory A. Gibson, Charles F. Mctiernan, Mark A. Kay and Hiroyuki Nakai
Mol Ther 14: 45-53; doi:10.1016/j.ymthe.2006.03.014
Stimulating Full-Length SMN2 Expression by Delivering Bifunctional RNAs via a Viral Vector
Travis Baughan, Monir Shababi, Tristan H. Coady, Alexa M. Dickson, Gregory E. Tullis and Christian L. Lorson
Mol Ther 14: 54-62; doi:10.1016/j.ymthe.2006.01.012
Adeno-associated Virus-Mediated Expression and Constitutive Secretion of Galanin Suppresses Limbic Seizure Activity in Vivo
Thomas J. McCown
Mol Ther 14: 63-68; doi:10.1016/j.ymthe.2006.04.004
The "Perivascular Pump" Driven by Arterial Pulsation is a Powerful Mechanism for the Distribution of Therapeutic Molecules within the Brain
Piotr Hadaczek, Yoji Yamashita, Hanna Mirek, Laszlo Tamas, Martha C. Bohn, Charles Noble, John W. Park and Krystof Bankiewicz
Mol Ther 14: 69-78; doi:10.1016/j.ymthe.2006.02.018
C-Terminal-Truncated Microdystrophin Recruits Dystrobrevin and Syntrophin to the Dystrophin-Associated Glycoprotein Complex and Reduces Muscular Dystrophy in Symptomatic Utrophin/Dystrophin Double-Knockout Mice
Yongping Yue, Mingju Liu and Dongsheng Duan
Mol Ther 14: 79-87; doi:10.1016/j.ymthe.2006.01.007
Induction of Dystrophin Expression by Exon Skipping in mdx Mice Following Intramuscular Injection of Antisense Oligonucleotides Complexed with PEG–PEI Copolymers
Jason H. Williams, Shashank R. Sirsi, Daniel R. Latta and Gordon J. Lutz
Mol Ther 14: 88-96; doi:10.1016/j.ymthe.2005.11.025
Metabolic Biotinylation Provides a Unique Platform for the Purification and Targeting of Multiple AAV Vector Serotypes
Gregory S. Arnold, A. Kate Sasser, Matthew D. Stachler and Jeffrey S. Bartlett
Mol Ther 14: 97-106; doi:10.1016/j.ymthe.2006.02.014
A Phase I Trial of Intravenous CG7870, a Replication-Selective, Prostate-Specific Antigen–Targeted Oncolytic Adenovirus, for the Treatment of Hormone-Refractory, Metastatic Prostate Cancer
Eric J. Small, Michael A. Carducci, James M. Burke, Ron Rodriguez, Lawrence Fong, Lynn van Ummersen, D. C. Yu, Junko Aimi, Dale Ando, Peter Working, David Kirn and George Wilding
Mol Ther 14: 107-117; doi:10.1016/j.ymthe.2006.02.011
Adenovirus Type 5 Interactions with Human Blood Cells May Compromise Systemic Delivery
Mark Lyons, David Onion, Nicky K. Green, Kriss Aslan, Ratna Rajaratnam, Miriam Bazan-Peregrino, Sue Phipps, Sarah Hale, Vivien Mautner, Leonard W. Seymour and Kerry D. Fisher
Mol Ther 14: 118-128; doi:10.1016/j.ymthe.2006.01.003
Recombinant Adenoviral Vectors Turn on the Type I Interferon System without Inhibition of Transgene Expression and Viral Replication
Eduardo Huarte, Esther Larrea, Rubén Hernández-Alcoceba, Carlos Alfaro, Oihana Murillo, Ainhoa Arina, Iñigo Tirapu, Arantza Azpilicueta, Sandra Hervás-Stubbs, Sergia Bortolanza, José L. Pérez-Gracia, María P. Civeira, Jesús Prieto, José I. Riezu-Boj and Ignacio Melero
Mol Ther 14: 129-138; doi:10.1016/j.ymthe.2006.02.015
Detection of cell cycle- and differentiation stage-dependent human telomerase reverse transcriptase expression in single living cancer cells
Anna Edqvist, Johan Rebetz, Marcus Järås, Anna Rydelius, Gunnar Skagerberg, Leif G. Salford, Bengt Widegren and Xiaolong Fan
Mol Ther 14: 139-148; doi:10.1016/j.ymthe.2005.12.018
Erratum
Erratum to "Sleeping Beauty-Mediated Transposition and Long-Term Expression in Vivo: Use of the LoxP/Cre Recombinase System to Distinguish Transposition-Specific Expression"
Paul R. Score, Lalitha R. Belur, Joel L. Frandsen, Jennifer L. Geurts, Tomoyuki Yamaguchi, Nikunj V. Somia, Perry B. Hackett, David A. Largaespada and R. Scott McIvor
Mol Ther 14: 149; doi:10.1016/j.ymthe.2006.03.011
Corrigendum
Corrigendum to "Biology of AAV Serotype Vectors in Liver-Directed Gene Transfer to Nonhuman Primates"
Guangping Gao, You Lu, Roberto Calcedo, Rebecca L. Grant, Peter Bell, Lili Wang, Joanita Figueredo, Martin Lock and James M. Wilson
Mol Ther 14: 150; doi:10.1016/j.ymthe.2006.04.002
