TABLE OF CONTENTS
Volume 13, Issue 5 (May 2006)
Editorial
Adventitious Mutations in Clinical Grade Vectors: An Issue to Consider?
David A. Williams and Timothy P. Cripe
Mol Ther 13: 831-832; doi:10.1016/j.ymthe.2005.03.040
Inside this Month
Top of pageResearch Update
Top of pageCommentary
Gene Therapy for Diabetic Cardiomyopathy: A New Approach for a Difficult Problem
Mol Ther 13: 835-838; doi:10.1016/j.ymthe.2006.03.013
Review Article
Gene Therapy for Lysosomal Storage Diseases
Mark S. Sands and Beverly L. Davidson
Mol Ther 13: 839-849; doi:10.1016/j.ymthe.2006.01.006
Dendritic Cell-Based Tumor Vaccines and Antigen Presentation Attenuators
Kevin Evel-Kabler and Si-Yi Chen
Mol Ther 13: 850-858; doi:10.1016/j.ymthe.2006.02.009
Original Articles
Widespread Correction of Lysosomal Storage in the Mucopolysaccharidosis Type VII Mouse Brain with a Herpes Simplex Virus Type 1 Vector Expressing 
-Glucuronidase
Bradford K. Berges, Srikanth Yellayi, Brian A. Karolewski, Richard R. Miselis, John H. Wolfe and Nigel W. Fraser
Mol Ther 13: 859-869; doi:10.1016/j.ymthe.2005.12.017
Intranasal Administration of the Growth-Compromised HSV-2 Vector 
RR Prevents Kainate-Induced Seizures and Neuronal Loss in Rats and Mice
Jennifer M. Laing, Michael D. Gober, Erin K. Golembewski, Scott M. Thompson, Kymberly A. Gyure, Paul J. Yarowsky and Laure Aurelian
Mol Ther 13: 870-881; doi:10.1016/j.ymthe.2005.12.013
A Mutant Type 2 Herpes Simplex Virus Deleted for the Protein Kinase Domain of the ICP10 Gene Is a Potent Oncolytic Virus
Xinping Fu, Lihua Tao, Rong Cai, Jonathan Prigge and Xiaoliu Zhang
Mol Ther 13: 882-890; doi:10.1016/j.ymthe.2006.02.007
Oncolytic Viruses Derived from the 
34.5-Deleted Herpes Simplex Virus Recombinant R3616 Encode a Truncated UL3 Protein
Megan J. Dambach, Jordan Trecki, Natalia Martin and Nancy S. Markovitz
Mol Ther 13: 891-898; doi:10.1016/j.ymthe.2006.02.006
Targeted Therapy of DNA Tumor Virus-Associated Cancers Using Virus-Activated Transcription Factors
Mi Jung Lim, Sang-Hyun Min, Jae-Jung Lee, Il Chul Kim, Ji Tae Kim, Dong Chul Lee, Nam-Soon Kim, Sangkyun Jeong, Mi Na Kim, Kwang Dong Kim, Jong-Seok Lim, Sang Bae Han, Hwan Mook Kim, Dae Seog Heo and Young Il Yeom
Mol Ther 13: 899-909; doi:10.1016/j.ymthe.2005.11.023
Blockade of TNF-
Decreases Both Inflammation and Efficacy of Intrapulmonary Ad.IFN Immunotherapy in an Orthotopic Model of Bronchogenic Lung Cancer
Michael J. Wilderman, Samuel Kim, Collin T. Gillespie, Jing Sun, Veena Kapoor, Anil Vachani, Daniel H. Sterman, Larry R. Kaiser and Steven M. Albelda
Mol Ther 13: 910-917; doi:10.1016/j.ymthe.2005.12.012
Immune Gene–Viral Therapy with Triplex Efficacy Mediated by Oncolytic Adenovirus Carrying an Interferon- Gene Yields Efficient Antitumor Activity in Immunodeficient and Immunocompetent Mice
Changqing Su, Linhui Peng, Jonathan Sham, Xinghua Wang, Qi Zhang, Daniel Chua, Chen Liu, Zhenfu Cui, Huibin Xue, Hongping Wu, Qin Yang, Baihe Zhang, Xinyuan Liu, Mengchao Wu and Qijun Qian
Mol Ther 13: 918-927; doi:10.1016/j.ymthe.2005.12.011
Selective Targeting of Checkpoint Kinase 1 in Tumor Cells with a Novel Potent Oncolytic Adenovirus
Qinglei Gao, Jianfeng Zhou, Xiaoyuan Huang, Gang Chen, Fei Ye, Yunping Lu, Kanyan Li, Liang Zhuang, Mei Huang, Gang Xu, Shxuan Wang and Ding Ma
Mol Ther 13: 928-937; doi:10.1016/j.ymthe.2005.12.009
Selective Intratumoral Amplification of an Antiangiogenic Vector by an Oncolytic Virus Produces Enhanced Antivascular and Anti-tumor Efficacy
Stephen H. Thorne, Betty Y.Y. Tam, David H. Kirn, Christopher H. Contag and Calvin J. Kuo
Mol Ther 13: 938-946; doi:10.1016/j.ymthe.2005.12.010
Role of SCC-S2 in Experimental Metastasis and Modulation of VEGFR-2, MMP-1, and MMP-9 Expression
Chuanbo Zhang, Debyani Chakravarty, Isamu Sakabe, Rajshree R. Mewani, Howard E. Boudreau, Deepak Kumar, Imran Ahmad and Usha N. Kasid
Mol Ther 13: 947-955; doi:10.1016/j.ymthe.2005.11.020
AAV Serotype 8-Mediated Gene Delivery of a Soluble VEGF Receptor to the CNS for the Treatment of Glioblastoma
Thomas C. Harding, Alshad S. Lalani, Byron N. Roberts, Satya Yendluri, Bo Luan, Kathryn E. Koprivnikar, Melissa Gonzalez-Edick, Guang Huan-Tu, Randy Musterer, Melinda J. VanRoey, Tomoko Ozawa, Richard A. LeCouter, Dennis Deen, Peter J. Dickinson and Karin Jooss
Mol Ther 13: 956-966; doi:10.1016/j.ymthe.2006.02.004
Long-term Doxycycline-regulated Transgene Expression in the Retina of Nonhuman Primates Following Subretinal Injection of Recombinant AAV Vectors
Knut Stieger, Guylène Le Meur, Françoise Lasne, Michel Weber, Jack-Yves Deschamps, Delphine Nivard, Alexandra Mendes-Madeira, Nathalie Provost, Laurent Martin, Philippe Moullier and Fabienne Rolling
Mol Ther 13: 967-975; doi:10.1016/j.ymthe.2005.12.001
Transduction of Myogenic Cells by Retargeted Dual High-Capacity Hybrid Viral Vectors: Robust Dystrophin Synthesis in Duchenne Muscular Dystrophy Muscle Cells
Manuel A. F. V. Gonçalves, Maarten Holkers, Christophe Cudré-Mauroux, Gijsbert P. van Nierop, Shoshan Knaän-Shanzer, Ietje van der Velde, Dinko Valerio and Antoine A.F. de Vries
Mol Ther 13: 976-986; doi:10.1016/j.ymthe.2005.11.018
Mechanical and Metabolic Rescue in a Type II Diabetes Model of Cardiomyopathy by Targeted Gene Transfer
Susumu Sakata, Djamel Lebeche, Yuri Sakata, Naoya Sakata, Elie R. Chemaly, Li Fan Liang, Prabhu Padmanabhan, Noboru Konishi, Miyako Takaki, Federica del Monte and Roger J. Hajjar
Mol Ther 13: 987-996; doi:10.1016/j.ymthe.2006.01.002
Genetic Targeting of Adenovirus Vectors Using a Reovirus 
1-Based Attachment Protein
Frederik H.E. Schagen, Felix M. Wensveen, Jan E. Carette, Terence S. Dermody, Winald R. Gerritsen and Victor W. van Beusechem
Mol Ther 13: 997-1005; doi:10.1016/j.ymthe.2005.11.019
Sustained FVIII Expression and Phenotypic Correction of Hemophilia A in Neonatal Mice Using an Endothelial-Targeted Sleeping Beauty Transposon
Li Liu, Cathryn Mah and Bradley S. Fletcher
Mol Ther 13: 1006-1015; doi:10.1016/j.ymthe.2005.11.021
In Vivo Effects of Myeloablative Alkylator Therapy on Survival and Differentiation of MGMTP140K-Transduced Human G-CSF-Mobilized Peripheral Blood Cells
Shanbao Cai, Jennifer R. Hartwell, Ryan J. Cooper, Beth E. Juliar, Emi Kreklau, Rafat Abonour, W. Scott Goebel and Karen E. Pollok
Mol Ther 13: 1016-1026; doi:10.1016/j.ymthe.2005.11.017
