TABLE OF CONTENTS

Volume 13, Issue 4 (April 2006)

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Editorial

An Emerging Consensus on Recommendations to Facilitate Clinical Gene Transfer

Mol Ther 13: 637-638; doi:10.1016/j.ymthe.2006.03.003

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Inside this Month

Inside this Month

Mol Ther 13: 639; doi:10.1016/j.ymthe.2006.03.006

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Research Update

Research Update

Mol Ther 13: 640; doi:10.1016/j.ymthe.2006.03.004

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Meeting Report

Critical Resources for Gene Therapy in Heart, Lung, and Blood Diseases Working Group

Savio L. C. Woo, Sonia I. Skarlatos, Mary M. Joyce, Thomas L. Croxton and Pankaj Qasba

Mol Ther 13: 641-643; doi:10.1016/j.ymthe.2005.12.007

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Review

Progress towards in Vivo Use of siRNAs

Mark A. Behlke

Mol Ther 13: 644-670; doi:10.1016/j.ymthe.2006.01.001

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Original Articles

rAAV2 Traffics through both the Late and the Recycling Endosomes in a Dose-Dependent Fashion

Wei Ding, Liang N. Zhang, Charles Yeaman and John F. Engelhardt

Mol Ther 13: 671-682; doi:10.1016/j.ymthe.2005.12.002

Vascular Bed-Targeted in Vivo Gene Delivery Using Tropism-Modified Adeno-associated Viruses

Lorraine M. Work, Hildegard Büning, Ela Hunt, Stuart A. Nicklin, Laura Denby, Nicola Britton, Kristen Leike, Margarete Odenthal, Uta Drebber, Michael Hallek and Andrew H. Baker

Mol Ther 13: 683-693; doi:10.1016/j.ymthe.2005.11.013

Targeting Vascular Injury Using Hantavirus-Pseudotyped Lentiviral Vectors

Zhong Qian, Makalah Haessler, Julio A. Lemos, Jody R. Arsenault, Jennifer E. Aguirre, James R. Gilbert, Russell P. Bowler and Frank Park

Mol Ther 13: 694-704; doi:10.1016/j.ymthe.2005.11.016

Combined Angiopoietin-1 and Vascular Endothelial Growth Factor Gene Transfer Restores Cavernous Angiogenesis and Erectile function in a Rat Model of Hypercholesterolemia

Ji-Kan Ryu, Chung-Hyun Cho, Hwa-Yean Shin, Sun U. Song, Seung-Min Oh, Minhyung Lee, Shuguang Piao, Jee-Young Han, In-Hoo Kim, Gou Young Koh and Jun-Kyu Suh

Mol Ther 13: 705-715; doi:10.1016/j.ymthe.2005.10.016

Biological Response Determinants in HSV-tk + Ganciclovir Gene Therapy for Prostate Cancer

Gustavo Ayala, Takefumi Satoh, Rile Li, Moshe Shalev, Yehoshua Gdor, Estuardo Aguilar-Cordova, Anna Frolov, Thomas M. Wheeler, Brian J. Miles, Kate Rauen, Bin S. Teh, E. Brian Butler, Timothy C. Thompson and Dov Kadmon

Mol Ther 13: 716-728; doi:10.1016/j.ymthe.2005.11.022

A Partial Down-regulation of WASP Is Sufficient to Inhibit Podosome Formation in Dendritic Cells

Aurelie Olivier, Laurence Jeanson-Leh, Gerben Bouma, Daniel Compagno, Johanna Blondeau, Khalil Seye, Sabine Charrier, Siobhan Burns, Adrian J. Thrasher, Olivier Danos, William Vainchenker and Anne Galy

Mol Ther 13: 729-737; doi:10.1016/j.ymthe.2005.11.003

A Histone Deacetylase Inhibitor Enhances Recombinant Adeno-associated Virus-Mediated Gene Expression in Tumor Cells

Takashi Okada, Ryosuke Uchibori, Mayumi Iwata-Okada, Masafumi Takahashi, Tatsuya Nomoto, Mutsuko Nonaka-Sarukawa, Takayuki Ito, Yuhe Liu, Hiroaki Mizukami, Akihiro Kume, Eiji Kobayashi and Keiya Ozawa

Mol Ther 13: 738-746; doi:10.1016/j.ymthe.2005.11.010

In vivo Gene Transfer to Healthy and Diabetic Canine Pancreas

Eduard Ayuso, Miguel Chillón, Félix García, Judith Agudo, Anna Andaluz, Ana Carretero, Mercè Monfar, Marta Moya, Joel Montané, Pedro J. Otaegui and Fàtima Bosch

Mol Ther 13: 747-755; doi:10.1016/j.ymthe.2005.10.017

Evaluation of Adenovirus Vectors Containing Serotype 35 Fibers for Vaccination

Nelson DiPaolo, Shaoheng Ni, Anuj Gaggar, Robert Strauss, Sebastian Tuve, Zong Yi Li, Daniel Stone, Dmitry Shayakhmetov, Nancy Kiviat, Papa Touré, Salif Sow, Branka Horvat and André Lieber

Mol Ther 13: 756-765; doi:10.1016/j.ymthe.2005.12.008

Development of Cell-Based Tuberculosis Vaccines: Genetically Modified Dendritic Cell Vaccine Is a Much More Potent Activator of CD4 and CD8 T Cells Than Peptide- or Protein-Loaded Counterparts

Janet I. Malowany, Sarah McCormick, Michael Santosuosso, Xizhong Zhang, Naoko Aoki, Patricia Ngai, Jun Wang, Jaina Leitch, Jonathan Bramson, Yonghong Wan and Zhou Xing

Mol Ther 13: 766-775; doi:10.1016/j.ymthe.2005.10.018

DNA Vaccines Increase Immunogenicity of Idiotypic Tumor Antigen by Targeting Novel Fusion Proteins to Antigen-Presenting Cells

Agnete B. Fredriksen, Inger Sandlie and Bjarne Bogen

Mol Ther 13: 776-785; doi:10.1016/j.ymthe.2005.10.019

Quantitative Comparison of Intracellular Trafficking and Nuclear Transcription between Adenoviral and Lipoplex Systems

Susumu Hama, Hidetaka Akita, Rie Ito, Hiroyuki Mizuguchi, Takao Hayakawa and Hideyoshi Harashima

Mol Ther 13: 786-794; doi:10.1016/j.ymthe.2005.10.007

Optimizing Plasmid-Based Gene Transfer for Investigating Skeletal Muscle Structure and Function

Jonathan D. Schertzer, David R. Plant and Gordon S. Lynch

Mol Ther 13: 795-803; doi:10.1016/j.ymthe.2005.09.019

Transcriptional Activation of Gene Expression by Pluronic Block Copolymers in Stably and Transiently Transfected Cells

Srikanth Sriadibhatla, Zhihui Yang, Catherine Gebhart, Valery Yu Alakhov and Alexander Kabanov

Mol Ther 13: 804-813; doi:10.1016/j.ymthe.2005.07.701

Metabolic Biotinylation of Lentiviral Pseudotypes for Scalable Paramagnetic Microparticle-Dependent Manipulation

Darren Nesbeth, Sharon L. Williams, Lucas Chan, Tony Brain, Nigel K. H. Slater, Farzin Farzaneh and David Darling

Mol Ther 13: 814-822; doi:10.1016/j.ymthe.2005.09.016

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Short Communication

Removal of Empty Capsids from Type 1 Adeno-Associated Virus Vector Stocks by Anion-Exchange Chromatography Potentiates Transgene Expression

Masashi Urabe, Ke-Qin Xin, Yoko Obara, Takayo Nakakura, Hiroaki Mizukami, Akihiro Kume, Kenji Okuda and Keiya Ozawa

Mol Ther 13: 823-828; doi:10.1016/j.ymthe.2005.11.024

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Corrigendum

Corrigendum to "Local Administration of an Adeno-Associated Viral Vector Expressing IL-10 Reduces Monocyte Infiltration and Subsequent Photoreceptor Damage During Experimental Autoimmune Uveitis"

Cathryn A. Broderick, Alexander J. Smith, Kam S. Balaggan, Anastasios Georgiadis, Prateek K. Buch, Peter C. Trittibach, Susie E. Barker, Gian-Marco Sarra, Adrian J. Thrasher, Andrew D. Dick and Robin R. Ali

Mol Ther 13: 829; doi:10.1016/j.ymthe.2005.09.013

Corrigendum to "Oncogenesis Following Delivery of a Nonprimate Lentiviral Gene Therapy Vector to Fetal and Neonatal Mice"

Mike Themis, Simon N. Waddington, Manfred Schmidt, Christof von Kalle, Yoahe Wang, Faisal Al-Allaf, Lisa G. Gregory, Megha Nivsarkar, Matthew Themis, Maxine V. Holder, Suzanne M.K. Buckley, Niraja Dighe, Alaine T. Ruthe, Ajay Mistry, Brian Bigger, Ahad Rahim, Tuan H. Nguyen, Didier Trono, Adrian J. Thrasher and Charles Coutelle

Mol Ther 13: 830; doi:10.1016/j.ymthe.2005.10.003

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