Molecular Therapy - Figure 4 for article: Transcriptional Activation of Gene Expression by Pluronic Block Copolymers in Stably and Transiently Transfected Cells

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Transcriptional Activation of Gene Expression by Pluronic Block Copolymers in Stably and Transiently Transfected Cells

Srikanth Sriadibhatla, Zhihui Yang, Catherine Gebhart, Valery Yu Alakhov and Alexander Kabanov

Figure 4.

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Effects of Pluronics on expression of GFP driven by different promoters in (A) mouse fibroblast cells GFP^NF-B-NIH3T3 (filled bars) and GFP^AP-1-NIH3T3 (striped bars) and (B) mouse myoblast cells GFP^NF-B-C2C12 (filled bars) and GFP^AP-1-C2C12 (striped bars). Cells were treated with Pluronics P85 (0.3, 0.7, and 1%) and L64 (0.03, 0.07, and 0.1%) for 3 h and the mean fluorescence values for (A) NIH3T3 and (B) C2C12 are presented. Data are reported as means plusminus SD (n = 3). Differences in treated versus control groups were considered significant at ^* P less than or equal to 0.05, ^** P 0.005.

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FIGURE 4

Transcriptional Activation of Gene Expression by Pluronic Block Copolymers in Stably and Transiently Transfected Cells

Figure 4.