TABLE OF CONTENTS
Volume 13, Issue S1 (May 2006)
Abstracts |
Abstracts |
Abstracts |
Abstracts |
Abstracts |
Author Index |
Keyword Index
Abstracts
1. Species Choice for Animal Modeling Cystic Fibrosis and Gene Therapy to the Airway
Xiaoming Liu, Ziying Yan, Meihui Luo, Liang N. Zhang, Cyndi Trygg, Carolina Smith, Keith Munson, William Guggino, Bruce Bunnell and John F. Engelhardt
Mol Ther 13: S1-S1; doi:10.1016/j.ymthe.2006.08.011
2. Identification of Different Modes of Viral Transport in the Non-Human Primate Brain after Convection-Enhanced Delivery of AAV Serotype Vectors
Marco A. Passini, Jie Bu, James C. Dodge, Lamya S. Shihabuddin, Tatyana V. Taksir, Denise A. Griffiths, John Bringas, Piotr Hadaczek, Mihaela Avramut, Seng H. Cheng and Krystof Bankiewicz
Mol Ther 13: S1-S1; doi:10.1016/j.ymthe.2006.08.012
3. Adeno-Associated Virus 2-Mediated Gene Transfer: Identification of a Cellular Protein Serine/Threonine Phosphatase Involved in Augmenting Vector Transduction Efficiency
Weihong Zhao, Jianqing Wu,, Li Zhong and Arun Srivastava
Mol Ther 13: S1-S2; doi:10.1016/j.ymthe.2006.08.013
4. Role of Notch1 in Augmenting Intracellular Trafficking and Transgene Expression of Recombinant Adeno-Associated Virus-2
Changchun Ren, April F. White and Selvarangan Ponnazhagan
Mol Ther 13: S2-S2; doi:10.1016/j.ymthe.2006.08.014
5. Mechanisms for Hairpin Loop Opening of |[ldquo]|Closed|[rdquo]| AAV-ITRs by Specific Cellular Endonuclease Activities, a Prerequisite for rAAV Vector Genome Recombinations In Vivo
Katsuya Inagaki, Theresa A. Storm, Mark A. Kay and Hiroyuki Nakai
Mol Ther 13: S2-S3; doi:10.1016/j.ymthe.2006.08.015
6. AAV8-Mediated Transgene Expression in Mice and Non-Human Primates
Hiroaki Mizukami, Jun Mimuro, Akira Ishiwata, Fumiko Ono, Takashi Matsushita, Takashi Okada, Masashi Urabe, Akihiro Kume, Keiji Terao, Yoichi Sakata and Keiya Ozawa
Mol Ther 13: S3-S3; doi:10.1016/j.ymthe.2006.08.016
7. Adeno-Associated Virus Type 2 (AAV2) Contains an Integrin alpha5beta1 Recognition Sequence Essential for Viral Cell Entry
Aravind Asokan, Julie B. Hamra, Mavis Agbandje-McKenna and Richard J. Samulski
Mol Ther 13: S3-S3; doi:10.1016/j.ymthe.2006.08.017
8. Adeno-Associated Virus 2-Mediated Gene Transfer: A Complex Interaction between Epidermal Growth Factor Receptor Protein Tyrosine Kinase Signaling and Ubiquitin/Proteasome Pathway in Transgene Expression
Li Zhong, Weihong Zhao, Jianqing Wu, Baozheng Li and Arun Srivastava
Mol Ther 13: S3-S4; doi:10.1016/j.ymthe.2006.08.018
9. Biology of rAAV8 in Mouse Liver Following Vector Administration at Birth
Katsuya Inagaki, Sally Fuess, Theresa A. Storm, Mark A. Kay and Hiroyuki Nakai
Mol Ther 13: S4-S4; doi:10.1016/j.ymthe.2006.08.019
10. Adeno-Associated Virus Type-1 Vectors Transduce Human Polarized Airway Epithelia without Polarity Preference
Ziying Yan, Diana C.M. Lei-Butters, Xiaoming Liu, Yulong Zhang, Meihui Luo, Liang Zhang, Roman Zak and John F. Engelhardt
Mol Ther 13: S4-S5; doi:10.1016/j.ymthe.2006.08.020
11. Transposition from a Gene-Deleted Adenoviral Vector Results in Phenotypic Correction in a Canine Model for Hemophilia B
Anja Ehrhardt, Hui Xu, Aaron M. Dillow, Stephen R. Yant, Timothy C. Nichols and Mark A. Kay
Mol Ther 13: S5-S5; doi:10.1016/j.ymthe.2006.08.022
12. Therapeutic Potential of the Chimeric Adenovirus 5/40 as Vector for Intestine-Directed Gene Therapy
Ester Rodriguez, Carolina Romero, Mireia Ferrer, Joan F. Burgue|[ntilde]|o, Ester Fernandez, Estel Gil, Hirofumi Hamada, Assumpcio Bosch and Miguel Chillon
Mol Ther 13: S5-S5; doi:10.1016/j.ymthe.2006.08.023
13. In Vivo Stable Transduction of Humanized Liver Tissue in Chimeric Mice Via High-Capacity Adenovirus-Lentivirus Hybrid Vector
Shuji Kubo, Miho Kataoka, Chise Tateno, Donna J. Palmer, Philip Ng, Katsutoshi Yoshizato and Noriyuki Kasahara
Mol Ther 13: S6-S6; doi:10.1016/j.ymthe.2006.08.024
14. High Efficiency and Long-Term Persistence In Vivo from a Helper Dependent Adenovirus/Epstein-Barr Virus Hybrid Vector
Sean D. Gallaher, Jose S. Gil and Arnold J. Berk
Mol Ther 13: S6-S6; doi:10.1016/j.ymthe.2006.08.025
15. Genetically Targeted Adenovirus Vector Carrying Reovirus |[sigma]|1-Based Attachment Protein for Improved Systemic Gene Delivery
Frederik H.E. Schagen, Harm C.A. Graat, Jan E. Carette, Terence S. Dermody, Michael A. vanGeer and Victor W. van Beusechem
Mol Ther 13: S6-S7; doi:10.1016/j.ymthe.2006.08.026
16. Direct Selection of Targeted Vector from a Random Peptide Library Displayed on Adenoviral Fiber Knob
Kazunori Aoki, Yoshiaki Miura, Kimiko Yoshida, Kazuteru Hatanaka, Takeshi Nishimoto, Shumpei Ohnami, Joanne T. Douglas, David T. Curiel and Teruhiko Yoshida
Mol Ther 13: S7-S7; doi:10.1016/j.ymthe.2006.08.027
17. Biodistribution, Innate Immune Response and Toxicity Following Intravenous Inoculation of Mice with Nonhuman Adenoviral Vectors
Dinesh S. Bangari, Anurag Sharma, Aseem Pandey, Harm HogenEsch and Suresh K. Mittal
Mol Ther 13: S7-S7; doi:10.1016/j.ymthe.2006.08.028
18. Comparison of Antitumor Activity of Cytosine Deaminase::Uracil Phosphoribosyl Transferase (CD::UPRT) and Purine Nucleoside Phosphorylase (PNP) Suicide Genes Using Replicative but Non-Disseminative Adenovirus Vectors
Jairo Jaime, Nadine Jabbour, William Parker, Eric Sorscher, Josephine Nalbantoglu and Bernard Massie
Mol Ther 13: S8-S8; doi:10.1016/j.ymthe.2006.08.029
19. A New, Plasmid-Based Adenoviral Vectoring System Derived from the Highly Immunogenic, Human Ad4 Strain
Zachary C. Hartman, Todd Mendelson and Andrea Amalfitano
Mol Ther 13: S8-S8; doi:10.1016/j.ymthe.2006.08.030
20. Construction and Characterization of Adenovirus Vectors Expressing Optimized Blood Stage Antigens of Plasmodium falciparum
Ping Chen, Svetlana Konovalova, Keith Limbach, Maureen E. Stefaniak, Noelle B. Patterson, Joseph J. Campo, Sheng Li, Richter King, Denise L. Doolan and Joseph T. Bruder
Mol Ther 13: S8-S9; doi:10.1016/j.ymthe.2006.08.031
21. Peptide-Targeted Ad19p-Based Adenoviral Vectors for Renal Gene Delivery
Laura Denby, Lorraine M. Work, Dan J. Von Seggern, Eugene Wu, Ela Hunt, Stuart A. Nicklin and Andrew H. Baker
Mol Ther 13: S9-S9; doi:10.1016/j.ymthe.2006.08.034
22. Creation of a Biological Pacemaker by Cell Fusion
Hee Cheol Cho, Yuji Kashiwakura and Eduardo Marb|[aacute]|n
Mol Ther 13: S9-S10; doi:10.1016/j.ymthe.2006.08.033
23. Catheter-Mediated Local Intramural Delivery of AdEC-SOD Inhibits Oxidative Stress and Reduces In-Stent Neointima by Accelerating Endothelial Cell Recovery in WHHL Rabbits Displaying Complex Human-Like Atherosclerotic Lesions
Olli Leppanen, Jan Hinrich Brasen, Tommi Heikura, Matias Inkala, Fabian Ahrens, Juha Rutanen, Anna-Liisa Levonen, Samar Basu, Mikko O. Laukkanen and Seppo Yla-Herttuala
Mol Ther 13: S10-S10; doi:10.1016/j.ymthe.2006.08.035
24. Widespread and Efficient Gene Delivery to the Heart and Liver Using AAV Serotype 9: Implications for Cardiovascular Disease and Hemophilia
Thierry VandenDriessche, Lieven Thorrez, Abel Acosta-Sanchez, Lilly Wang, Veerle Gillijns, Ma Ling, Herman Vandenburgh, Nico Mertens, Nico Callewaert, James Wilson, Desire Collen and Marinee Chuah
Mol Ther 13: S10-S11; doi:10.1016/j.ymthe.2006.08.036
25. Development and Characterization of Viral Vectors with High Specificity for Atherosclerotic Plaques
Katie M. White, Hildergard Buening, Lorraine M. Work, Michael Hallek, Stuart A. Nicklin and Andrew H. Baker
Mol Ther 13: S11-S11; doi:10.1016/j.ymthe.2006.08.037
26. Lentiviral Vector Delivery of vMIP-II Using Both Transplanted Endothelial and Progenitor Cells Enhances a Robust and Functional Angiogenesis In Vivo
Stephanie Cherqui, Camille Thorpe, Sunil M. Kurian and Daniel R. Salomon
Mol Ther 13: S11-S11; doi:10.1016/j.ymthe.2006.08.038
27. Prevention of Cardiac Remodeling and Heart Failure in Dahl-Salt Sensitive Rats by AAV Vector-Mediated Interleukin-10 Expression
Mutsuko Sarukawa, Takashi Okada, Toru Yoshioka, Takayuki Ito, Tatsuya Nomoto, Hiroaki Mizukami, Akihiro Kume, Keiji Yamamoto, Uichi Ikeda, Kazuyuki Shimada and Keiya Ozawa
Mol Ther 13: S12-S12; doi:10.1016/j.ymthe.2006.08.039
28. rAAV2/9 Mediated Gene Delivery of Acid |[alpha]|-Glucosidase Corrects the Cardiac Phenotype in a Mouse Model of Pompe Disease
Christina A. Pacak, Cathryn Mah, Kerry O. Cresawn, Melissa A. Lewis, Sean Germain and Barry J. Byrne
Mol Ther 13: S12-S12; doi:10.1016/j.ymthe.2006.08.040
29. Effect of AAV6-Mediated TIMP-2 Overexpression in a Murine Model of Heart Failure
Satsuki Mori, Xiaodong Zhu, Gregory Gibson, Benjamin Burkhead and Charles F. McTiernan
Mol Ther 13: S13-S13; doi:10.1016/j.ymthe.2006.08.041
30. Cardiac-Specific Gene Expression Using Pseudotyped AAV Vectors and the Cardiac Troponin-T Promoter
Konkal-Matt R. Prasad, Zequan Yang, Yaqin Xu, Stuart S. Berr and Brent A. French
Mol Ther 13: S13-S13; doi:10.1016/j.ymthe.2006.08.042
31. Dystrophin Expression in Muscles of Duchenne Muscular Dystrophy Patients Following High-Density Injections of Normal Myogenic Cells
Jacques P. Tremblay, Daniel Skuk, Marlyne Goulet, Brigitte Roy, Pierre Chapdelaine, Raynald Roy, Francine Dugr|[eacute]|, Jean-Pierre Bouchard, Jean-Guy Lachance, Michel Sylvain, Louise Desch|[ecirc]|nes and H|[eacute]|l|[egrave]|ne Senay
Mol Ther 13: S13-S14; doi:10.1016/j.ymthe.2006.08.044
32. Improvement of Muscle Mass Using shRNA Targeting Myostatin or Activin Receptor IIb
Julie Dumonceaux, Solenne Marie and Luis Garcia
Mol Ther 13: S14-S14; doi:10.1016/j.ymthe.2006.08.045
33. Systemic Delivery of AAV8/DC190-GAA to Pompe Mice Normalizes Muscle Pathology and Corrects Motor Function Deficits
R.J. Ziegler, M.A. Zhao, S.D. Bercury, J.A. Fidler, J.W. Foley, D. Armentano, S. Ryan, T. Taksir, D. Griffiths, L.S. Shihabuddin, R.K. Scheule and S.H. Cheng
Mol Ther 13: S14-S14; doi:10.1016/j.ymthe.2006.08.046
34. Phi C31 Integrase System Enhances Dystrophin Gene Expression in Skeletal Muscle of Mouse Models for Duchenne Muscular Dystrophy
Carmen Bertoni, Sohail Jarrahian, Thurman M. Wheeler, Yining Li, Eric C. Olivares, Michele P. Calos and Thomas A. Rando
Mol Ther 13: S14-S15; doi:10.1016/j.ymthe.2006.08.047
35. Systemic Administration of rAAV6-Microdystrophin Preserves Muscle Function and Extends Lifespan in the Dystrophin-/Utrophin- Mouse Model of Severe Muscular Dystrophy
Paul Gregorevic, Michael J. Blankinship, Elina Minami, James M. Allen, Charles E. Murry and Jeffrey S. Chamberlain
Mol Ther 13: S15-S15; doi:10.1016/j.ymthe.2006.08.048
36. Transplantation of SM/C-2.6+ Satellite Cells Transduced with Micro-Dystrophin CS1 cDNA by Lentiviral Vector into mdx Mice
Madoka Ikemoto, So-ichiro Fukada, Akiyoshi Uezumi, Satoru Masuda, Ampong Beryl Nyamekye, Hiroyuki Miyoshi, Hiroshi Yamamoto, Yuko Miyagoe-Suzuki and Shin'ichi Takeda
Mol Ther 13: S15-S15; doi:10.1016/j.ymthe.2006.08.049
37. Long-Term Expression of Mini-Human Dystrophin in Transgenic mdx Mice Improves Dystrophic Muscle Functions
Bing Wang, Juan Li, Chunlian Chen, Xiancheng Jiang, Terry O'Day, Jon Watchko and Xiao Xiao
Mol Ther 13: S16-S16; doi:10.1016/j.ymthe.2006.08.050
38. Morpholino Antisense Oligonucleotide Induced Exon Skipping Efficiently Restores Dystrophin Expression in the mdx Mouse
Dominic J. Wells, Caroline McCulley, Anna Graham, Ke Liu and Kim E. Wells
Mol Ther 13: S16-S16; doi:10.1016/j.ymthe.2006.08.051
39. Evaluation of rAAV-1 vs rAAV-8 Vectors and Their Mode of Delivery in Nonhuman Primate Skeletal Muscle
Alice Toromanoff, Yan Cherel, Jack-Yves Deschamps, Valder R. Arruda, Katherine A. High, Hansell H. Stedman, Mark E. Haskins, Fabienne Rolling, Ignacio Anegon, Philippe Moullier and Caroline Le Guiner
Mol Ther 13: S16-S17; doi:10.1016/j.ymthe.2006.08.052
40. Increased Transgene Expression of Dystrophin in mdx Muscle by RNAi-Mediated Silencing of Calpain Expression
Makiya Nishikawa, Kazuhiro Hirata, Kazuya Machida, Yuki Takahashi, Katsutoshi Yuasa, Shin'ichi Takeda and Yoshinobu Takakura
Mol Ther 13: S17-S17; doi:10.1016/j.ymthe.2006.08.053
41. Evaluation of Lung Cancer Virotherapy with Oncolytic Semliki Forest Virus Using Immunodeficient Rodent Tumor Model
Ann-Marie M|[auml]||[auml]|tt|[auml]|, Tiina Wahlfors, Katja H|[auml]|kkinen, Linda Jansson, Markus V|[auml]|h|[auml]|-Koskela, Ari Hinkkanen, Kimmo M|[auml]|kinen and Jarmo Wahlfors
Mol Ther 13: S17-S17; doi:10.1016/j.ymthe.2006.08.055
42. Resistance of Primary Ovarian Cancer Cells to Viral Oncolysis
Robert Strauss, Pavel Sova, Ying Liu, Zong Yi Li, Nicole Urban, Charles Drescher, Nancy Kiviat and Andre Lieber
Mol Ther 13: S18-S18; doi:10.1016/j.ymthe.2006.08.056
43. Long-Term T Cell Activation Following Combined In Situ Gene Therapy and Intensity-Modulated Radiotherapy Compared to Gene Therapy as Mono-Therapy in Prostate Cancer Patients
Tetsuo Fujita, Bin S. Teh, Terry L. Timme, Wei-Yuan Mai, Takefumi Satoh, Nobuyuki Kusaka, Koji Naruishi, Elmoataz Abdelfattah, Estuardo Aguilar-Cordova, Brian J. Miles, E. Brian Butler and Timothy C. Thompson
Mol Ther 13: S18-S18; doi:10.1016/j.ymthe.2006.08.057
44. Combination of Oncolytic Measles Virus Strains and Radiation Therapy Has Synergistic Activity in the Treatment of Glioblastoma Multiforme
Chunsheng Liu, Jann N. Sarkaria, Cory Allen, Paula J. Zollman, C. David James, Stephen J. Russell and Evanthia Galanis
Mol Ther 13: S19-S19; doi:10.1016/j.ymthe.2006.08.058
45. Paclitaxel-TRAIL Enhances the Distribution of Oncolytic Herpes Simplex Virus-1 in a Human Mammary Carcinoma Xenograft
Satoshi Nagano, Jean Y. Perentes, Rakesh K. Jain and Yves Boucher
Mol Ther 13: S19-S19; doi:10.1016/j.ymthe.2006.08.059
46. Phase I/II Study of Adenoviral Vector Delivery of HSV-tk Gene and the Intravenous Administration of Ganciclovir in Men with Local Recurrence of Prostate Cancer after Hormonal Therapy
Yasutomo Nasu, Haruki Kaku, Shin Ebara, Takashi Saika, Hiromi Kumon and Timothy C. Thompson
Mol Ther 13: S19-S20; doi:10.1016/j.ymthe.2006.08.060
47. A Combination Therapy of Selective Intraarterial Gendicine Infusion with Chemotherapy for Locally Advanced Head and Neck Carcinoma
Longjiang Li, Yuanding Huang, Lijuan Wang, Yi Li, Yuming Wen and Bo Han
Mol Ther 13: S20-S20; doi:10.1016/j.ymthe.2006.08.061
48. Adeno-Associated Viral (AAV) Vector- Mediated Systemic Delivery of mda-7/IL24 Inhibits Tumor Growth by Antitumor Bystander Effect
Ichiro Tahara, Koichi Miyake, Toshiyuki Kurai, Yukihiko Hirai, Eiji Uchida, Takashi Tajiri and Takashi Shimada
Mol Ther 13: S20-S20; doi:10.1016/j.ymthe.2006.08.062
49. Inhibition of Acid Ceramidase Expression by Small Interfering RNA Sensitize Human Prostae Cancer Cells to Apoptin Induced Cell Death
Xiang Liu, Guiwen Guo, Saeed N. Elojeimy, David H. Holman, Ayman Mahdy, Alicja Bielawska, Jacek Bielawski, Seymon Rubinchik, Jian-yun Dong, Thomas Keane, Mahvash Tavassoli, Yusuf A. Hannun and James N. Norris
Mol Ther 13: S21-S21; doi:10.1016/j.ymthe.2006.08.063
50. Adenoviral-Mediated Gene Transfer of Single Chain Fv 425:sTRAIL Fusion Protein Induces Target Cell Restricted Apoptosis in EGFR- Positive Tumor Cells and a Potent Bystander Effect
Hidde J. Haisma, Marike Dijkstra, Edwin Bremer and Wijnand Helfrich
Mol Ther 13: S21-S21; doi:10.1016/j.ymthe.2006.08.064
51. Clinical Study of Personalized Therapeutics Based on Genomic/Proteomic Profiling
John Nemunaitis, Neil Senzer, Jerry Shen, Phillip Maples, Donald Rao, Alex Tong, Padmasini Kumar, Joe Kuhn, Yu-An Zhang, Jian Liao, Iya Khalil, Colin Hill and Adi Gazdar
Mol Ther 13: S21-S22; doi:10.1016/j.ymthe.2006.08.066
52. A Phase 1 Dose-Escalation Trial of Intravesical CG0070 for Superficial Transitional Cell Carcinoma (TCC) of the Bladder after Bacillus Calmette-Guerin (BCG) Failure
Neil Senzer, John Nemunaitis, Michael Goldstein, James Arseneau, Don Lamm, Joe Stephenson, Harry Tsai, Kristina Neal, Junko Aimi, D.C. Yu, Daniel Maslyar, John Corman, James Mckiernan and James Burke
Mol Ther 13: S22-S22; doi:10.1016/j.ymthe.2006.08.067
53. Preliminary Results of a Pilot Phase I Clinical Trial of Adoptive Immunotherapy for B Cell Lymphoma Using CD8+ T Cells Genetically Modified To Express a Chimeric T Cell Receptor Recognizing CD20
Oliver W. Press, Jinjuan Wang, Catherine G. Lindgren, Eric Y. Chen, Ajay K. Gopal, John M. Pagel, Xiaojun Qian, Stanley R. Riddell, Philip D. Greenberg, Andrew Raubitschek and Michael C. Jensen
Mol Ther 13: S22-S23; doi:10.1016/j.ymthe.2006.08.068
54. TNFerade|[trade]| in Pancreas Cancer: Local Activation with Systemic Potential
Neil Senzer, John Nemunaitis, J. Macko and Thomas Davis
Mol Ther 13: S23-S23; doi:10.1016/j.ymthe.2006.08.069
55. Translating Preclinical Results into the Clinical Development of PV701, an Oncolytic Virus
Robert M. Lorence, M. Scot Roberts, James D. O'Neil, Pete T. Buasen, Li Zhang, William S. Groene and Michael K. Bamat
Mol Ther 13: S23-S23; doi:10.1016/j.ymthe.2006.08.070
56. The Efficacy of Replicating Virotherapy for Tumors Involves a Complex Equilibrium between Virus, Tumor and the Immune System
Rosa Maria Diaz, Feorilo Galivo, Jian Qiao, Jill Thompson, Timothy Kottke, John Bell, Glen Barber and Richard Vile
Mol Ther 13: S24-S24; doi:10.1016/j.ymthe.2006.08.071
57. Targeted Gene Delivery of Alpha-Interferon by Genetically Modified Hematopoietic Cells Inhibits Glioma Vascularization and Growth without Systemic Toxicity
Michele DePalma, Rossella Galli, Mary Anna Venneri, Letterio S. Politi, Ferdinando Pucci, Lucia Sergi Sergi, Elena Binda, Ehud Hauben and Luigi Naldini
Mol Ther 13: S24-S24; doi:10.1016/j.ymthe.2006.08.072
58. Oncolytic Measles Virus Delivery by Infected Cell Carriers |[ndash]| A Strategy To |[ldquo]|By-Pass|[rdquo]| the Pre-Existing Humoral Immune Response
Ianko D. Iankov, Boris R.A. Blechacz, Guy E. Griesmann, Mark J. Federspiel and Stephen J. Russell
Mol Ther 13: S24-S25; doi:10.1016/j.ymthe.2006.08.073
59. Targeted Gene Therapy of Malignant Glioma with Adult Stem Cells
Hrvoje Miletic, Yvonne Fischer, Tsanan Giroglou, Sara Litwak, Sandra Winkeler, Uwe Himmelreich, Werner Stenzel, Martina Deckert, Andreas H. Jacobs, Harald Neumann and Dorothee von Laer
Mol Ther 13: S25-S25; doi:10.1016/j.ymthe.2006.08.074
60. Radiation Improves Local Delivery of a Virus-Mimicking Nanostructure Complex in Tumors
Rebecca A. Abela, Liang Xu, Theodore S. Lawrence and Ming Zhang
Mol Ther 13: S25-S25; doi:10.1016/j.ymthe.2006.08.075
61. Successful Gene Therapy of a Mouse Model of Congenital Erythropoietic Porphyria with an Erythroid-Specific Lentiviral Vector
Elodie Robert, Magalie Lalanne, Isabelle Lamrissi-Garcia, Muriel Cario-Andre, Cecile Ged, Hubert De Verneuil and Francois Moreau-Gaudry
Mol Ther 13: S25-S26; doi:10.1016/j.ymthe.2006.08.077
62. Proteasome Activity Restricts Lentiviral Gene Transfer into Hematopoietic Stem Cells and Is Down-Regulated by Cytokines That Enhance Transduction
Francesca R. Santoni de Sio, Paolo Cascio, Anna Zingale, Mauro Gasparini and Luigi Naldini
Mol Ther 13: S26-S26; doi:10.1016/j.ymthe.2006.08.078
63. Long-Term Constitutive Expression of the Therapeutic Gene, IL2RG, Causes T-Cell Lymphomas in a Gene Therapy Model for XSCID
Niels-Bjarne Woods, Virginie Bottero, Manfred Schmidt, Christof von Kalle and Inder M. Verma
Mol Ther 13: S26-S27; doi:10.1016/j.ymthe.2006.08.079
64. Rescue of B Cell Development in an Animal Model of X-Linked Agammaglobulinemia (XLA) Via B Lineage-Specific Lentiviral Gene Therapy
Wenying Zhang, Stephanie Humblet-Baron, Kevin Kipp, Socheath Khim, Jordan Jarjour, Karen Sommer, Brigid Stirling, Lia Pernell and David J. Rawlings
Mol Ther 13: S27-S27; doi:10.1016/j.ymthe.2006.08.080
65. Long-Term Effects of Hematopoietic Stem Cell Gene Therapy in the Murine Model of Wiskott-Aldrich Syndrome: Persistence of Functional Correction of T Cells and Lack of Malignant Trasformation
Francesco Marangoni, Lo|[iuml]|c Dupr|[eacute]|, Samantha Scaramuzza, Cristina Panaroni, Sara Trifari, Raisa Jofra Hern|[aacute]|ndez, Adrian J. Thrasher, Anne Galy, Alessandro Aiuti, Luigi Naldini and Maria Grazia Roncarolo
Mol Ther 13: S27-S28; doi:10.1016/j.ymthe.2006.08.081
66. Gene Transfer-Mediated Expression of Murine Factor VIIa Improves Clot Formation in a Mouse Model for Bernard-Soulier Syndrome
Majed N. Aljamali, Paris Margaritis, Valder R. Arruda, Alex Schlachterman, Danielle Dunn, Jerry Ware and Katherine A. High
Mol Ther 13: S28-S28; doi:10.1016/j.ymthe.2006.08.082
67. The Chicken Hypersensitive Site (cHS4) Insulator Element Reduces Position Effects Thereby Increasing Expression from Globin Lentiviral Vectors
Paritha I. Arumugam, Jessica Scholes, Ping Xia, Natalya Perelman, Alexander Zarzuela, Jiing-Kuan Yee and Punam Malik
Mol Ther 13: S28-S28; doi:10.1016/j.ymthe.2006.08.083
68. Evidence for Correction of Mutations in the c-Kit Gene by rAAV Mediated Gene Targeting in W/Wv Mice
Arthur W. Nienhuis, John T. Gray, Serena Vayda, Amanda Cline, Marguerite V. Evans-Galea and David M. Bodine
Mol Ther 13: S29-S29; doi:10.1016/j.ymthe.2006.08.084
69. Selection of Hematopoietic Progenitor and Stem Cells in Transplanted Rhesus Macaques Using MGMT and HOXB4 Lentiviral Vectors
Yan Shou, John Gray, Brian Agricola, Zhijun Ma, Geeta K. Nair, Clinton F. Stewart, Derek A. Persons and Brian P. Sorrentino
Mol Ther 13: S29-S29; doi:10.1016/j.ymthe.2006.08.085
70. Long Term Correction of beta-Thalassemia by Transplantation of Transduced Hematopoietic Stem Cells
Annarita Miccio, Rossano Cesari, Francesco Lotti, Claudia Rossi, Francesca Tiboni, Francesca Sanvito, Maurilio Ponzoni, Samantha Routledge, Michael Antoniou and Giuliana Ferrari
Mol Ther 13: S30-S30; doi:10.1016/j.ymthe.2006.08.086
71. Alpha 1 Antitrypsin (AAT) Gene Therapy for the Prevention of Type 1 Diabetes
Sihong Song, Yuanqing Lu, Mei Tang, Bin Zhang, Clive Wasserfall, Martha Campbell-Thompson and Mark Atkinson
Mol Ther 13: S30-S30; doi:10.1016/j.ymthe.2006.08.088
72. Intravascular Interaction between Adenovirus and Platelets Promotes Adenovirus Sequestration, Degradation and Toxicity
Daniel Stone, Shaoheng Ni, Zong-Yi Li, Dmitry Shayakhmetov and Andre Lieber
Mol Ther 13: S30-S31; doi:10.1016/j.ymthe.2006.08.089
73. Cats Produce a Potent CTL Response after Neonatal Gene Therapy That Can Be Blocked with CTLA4-Ig
Katherine P. Ponder, Baomei Wang, Ping Wang, Xiucui Ma, Ramin Herati, Bin Wang, Karyn Cullen, Patty O'Donnell, Tina M. Primeau and Mark E. Haskins
Mol Ther 13: S31-S31; doi:10.1016/j.ymthe.2006.08.090
74. Cellular Immunity to Adeno-Associated Virus Capsid Attenuates Transgene Expression in the Liver
Samuel L. Murphy, Denise Sabatino, Federico Mingozzi, Shyrie Edmonson and Katherine High
Mol Ther 13: S31-S32; doi:10.1016/j.ymthe.2006.08.091
75. Protease-Activated Receptor 2 as a Novel Target for Immune Modulation for AAV-Mediated Gene Transfer to Skeletal Muscle
Stefano Baila, Christian Furlan Freguia, Danielle Dunn, Federico Mingozzi, Joerg Schuettrumpf and Valder R. Arruda
Mol Ther 13: S32-S32; doi:10.1016/j.ymthe.2006.08.092
76. In Vivo Suppression of Cytotoxic T Cell Responses by CD4+ Regulatory T Cells Activated by Hepatic Gene Transfer
Lixin Wang, Eric Dobrzynski, Julie Fitzgerald, Ou Cao and Roland W. Herzog
Mol Ther 13: S32-S32; doi:10.1016/j.ymthe.2006.08.093
77. TLR and Myd88 Signaling Pathway Is Required for the Full Induction of Host Adaptive Immune Responses to Adenoviral Vectors and Transgenes
Zhe Zhang, Yan Zhi, Joanita M. Figueredo, Roberto Calcedo, James R. Miller, Guang-Ping Gao and James M. Wilson
Mol Ther 13: S33-S33; doi:10.1016/j.ymthe.2006.08.094
78. Regulation of Immune Responses Against Factor VIII Following Nonviral Gene Transfer in Hemophilia A and FOXP3 Transgenic Mouse Models
Benjamin R. Harmeling, Steven Ziegler, Troy Torgerson, Liping Chen, Hans D. Ochs, David J. Rawlings and Carol H. Miao
Mol Ther 13: S33-S33; doi:10.1016/j.ymthe.2006.08.095
79. Systemic Administration of Lentiviral Vectors Triggers Innate Host Responses
Brian D. Brown, Ehud Hauben, Giovanni Sitia, Anna Zingale, Lucia Sergi Sergi, Lucca Guidotti, Maria Grazia Roncarolo and Luigi Naldini
Mol Ther 13: S33-S34; doi:10.1016/j.ymthe.2006.08.096
80. Pre-Existing Cytotoxic T-Lymphocyte (CTL) Responses to the AAV CAP Protein Do Not Interfere with AAV Transgene Expression in Mice
William M. Siders, Johanne Kaplan, Michael Lukason, Jacqueline Shields, Lisa Woodworth, Sam Wadsworth and Abraham Scaria
Mol Ther 13: S34-S34; doi:10.1016/j.ymthe.2006.08.097
81. Hippocampal Gene Knockdown of BACE1 by Lentiviral Gene Transfer of siRNA Reduces Amyloid Pathology and Improves Memory Performance in APP Transgenic Mice
Oded Singer, Robert A. Marr, Edward Rockenstein, Leslie Crow, Fred H. Gage, Inder M. Verma and Eliezer Masliah
Mol Ther 13: S34-S34; doi:10.1016/j.ymthe.2006.08.099
82. Cftr Gene Targeting in Murine ES Cells Mediated by the SFHR Technique
Federica Sangiuolo, Maria Favia, Lorenzo Guerra, Antonio Filareto, Maria Lucia Scaldaferri, Rosa Caroppo, Paola Spitalieri, Ruggiero Mango, Emanuela Bruscia, Dieter Gruenert, Valeria Casavola, Massimo De Felici and Giuseppe Novelli
Mol Ther 13: S34-S35; doi:10.1016/j.ymthe.2006.08.100
83. Cell-Type Specific Delivery of siRNAs with Aptamer-siRNA Chimeras
Paloma H. Giangrande, James O. McNamara, Eran Andrecheck, Eli Gilboa and Bruce A. Sullenger
Mol Ther 13: S35-S35; doi:10.1016/j.ymthe.2006.08.101
83. RNA Silencing: Role of Interferon System Components in Non-Specific Effects Induced by Chemically Synthesized Small Interfering RNAs, Enzymatically Synthesized Small Interfering RNAs and Short Hairpin RNAs
Christopher S. McAllister and Charles E. Samuel
Mol Ther 13: S35-S35; doi:10.1016/j.ymthe.2006.08.102
85. Von Willebrand Factor (VWF) Gene Targeting by Double-Strand Break Enhanced Homologous Recombination
Nicole L. Prokopishyn, Brian R. Davis, Jonathan B. Rosenberg, Michael DiCola, Jennifer Brosius, R. Michael Blaese and Richard A. Metz
Mol Ther 13: S35-S36; doi:10.1016/j.ymthe.2006.08.103
86. Inhibition of Choroidal Neovascularization In Vivo by Adenovirus Mediated Delivery of Short Hairpin RNAs Targeting Vascular Endothelial Growth Factor as a Potential Therapy for Age Related Macular Degeneration
Siobhan Cashman and Rajendra Kumar-Singh
Mol Ther 13: S36-S36; doi:10.1016/j.ymthe.2006.08.104
87. Efficient Delivery of Small Interfering RNA Targeting Pro-Inflammatory Cytokines in Experimental Arthritis
Maroun Khoury, Virginie Escriou, Pascale Louis-Plence, Dani|[egrave]|le Noel, Daniel Scherman, Christian Jorgensen, and Florence Apparailly
Mol Ther 13: S36-S36; doi:10.1016/j.ymthe.2006.08.105
88. Synthetic siRNAs for Huntington's Disease Therapy
Patrick D. Staber, Chandra Vargeese, Ines H. Martins, Barry Polisky, Alex Mas-Monteys, Scott Q. Harper and Beverly L. Davidson
Mol Ther 13: S36-S37; doi:10.1016/j.ymthe.2006.08.106
89. Gene Targeting of |[beta]|-Globin IVS2 Using Sequence-Specific Peptide Nucleic Acids
Jean Y. Kuan, Ryszard Kole, Peter E. Nielsen and Peter M. Glazer
Mol Ther 13: S37-S37; doi:10.1016/j.ymthe.2006.08.107
90. miRNA Shuttles Improve Therapeutic RNAi
Ryan L. Boudreau and Beverly L. Davidson
Mol Ther 13: S37-S37; doi:10.1016/j.ymthe.2006.08.108
91. Retroviral Vector Integrations Relate to Hematopoietic Stem Cell Gene Expression Patterns
Martijn H. Brugman, Karin Pike-Overzet, Carla Oerlemans-Bergs, Sigrid Swagemakers, Dick de Ridder, Frank J.T. Staal, Monique M.A. Verstegen and Gerard Wagemaker
Mol Ther 13: S37-S38; doi:10.1016/j.ymthe.2006.08.110
92. Gene Transfer to Ocular Stem Cells by Early Gestational Intra-Amniotic Injection of Lentiviral Vector
Masayuki Endo, Phil W. Zoltick, Daniel C. Chung, Jean Bennett and Alan W. Flake
Mol Ther 13: S38-S38; doi:10.1016/j.ymthe.2006.08.111
93. Increased Number of Lung CD34+ Sca-1+ Putative Stem Cells Mediated by Adenovirus Overexpression by Sonic Hedgehog in the Respiratory Tract of Adult Mice
Anja Krause, Ju Joh, Austen Gess, Howard Lou, Ronald G. Crystal and Stefan Worgall
Mol Ther 13: S38-S38; doi:10.1016/j.ymthe.2006.08.112
94. Modulation of Postnatal Muscle-Derived Stem Cell Fate Using siRNA
Jonathan B. Pollett, Karin A. Corsi, Jessica Tebbets, Bridget M. Deasy and Johnny Huard
Mol Ther 13: S39-S39; doi:10.1016/j.ymthe.2006.08.113
95. Effective Genetic Engineering of Human Embryonic Stem Cells Using the Sleeping Beauty Transposon System
Andrew Wilber, Jonathan L. Linehan, Xinghui Tian, R. Scott McIvor and Dan S. Kaufman
Mol Ther 13: S39-S39; doi:10.1016/j.ymthe.2006.08.114
96. Enforced HoxB4 Expressed Hematopoietic Stem Cells Transdifferentiate into Oligodendrocytes in Adult Mouse Brain
Noriko Miyake, Koichi Miyake, Sanae Hisayasu, Stefan Karlsson and Takashi Shimada
Mol Ther 13: S39-S40; doi:10.1016/j.ymthe.2006.08.115
97. Translational Studies toward Optimizing In Vivo Bone Marrow Stem Cell Gene Transfer Using Lentiviral Vector
D. Nicole Worsham, Daren Wang, Christof von Kalle, David A. Williams and Dao Pan
Mol Ther 13: S40-S40; doi:10.1016/j.ymthe.2006.08.116
98. Enrichment and Characterization of Ovarian Cancer Stem Cells
Zong Yi Li, Robert Strauss, Pavel Sova, Shaoheng Ni, Mujun Yu, Dmitry Shayakhmetov, Charles Drescher, Nicole Urban and Andre Lieber
Mol Ther 13: S40-S41; doi:10.1016/j.ymthe.2006.08.117
99. Dedifferentiation of Myotubes and Redifferentiation into an Osteogenic Lineage: A Cre-Lox System Study
Anne Olshanski, Hairong Peng, Xiao Xiao and Johnny Huard
Mol Ther 13: S41-S41; doi:10.1016/j.ymthe.2006.08.118
100. Inducible and Reversible Transgene Expression in Human Stem Cells Stably Transduced by Novel Lentiviral Vectors
Betty Y. Zhou, Zhaohui Ye, Peter Gao and Linzhao Cheng
Mol Ther 13: S41-S41; doi:10.1016/j.ymthe.2006.08.119
101. Molecular Mechanism Responsible for High Level Transgene Expression in Murine and Nonhuman Primate Liver with the Second Generation of Novel AAV Serotype Vectors
You Lu, Xun Sun, Larry T. Bish, Julie C. Johnston, Roberto Calcedo, Rebecca L. Grant, Gaung-Ping Gao and James M. Wilson
Mol Ther 13: S42-S42; doi:10.1016/j.ymthe.2006.08.121
102. Activation of the LMO2 Gene in Human Lymphoid Cells by rAAV-Mediated Targeted Insertion of a Single LTR Expression Cassette into the First Intron
Byoung Y. Ryu, John T. Gray, David M. Bodine and Arthur W. Nienhuis
Mol Ther 13: S42-S42; doi:10.1016/j.ymthe.2006.08.122
103. A Screen for Host Cellular Proteins That Interact with Adeno-Associated Virus Capsid Proteins Reveals Proteins Involved in AAV8 Transduction
Bassel Akache, Sally Fuess, Dirk Grimm and Mark A. Kay
Mol Ther 13: S42-S43; doi:10.1016/j.ymthe.2006.08.123
104. Role of the HI Loop in the Adeno-Associated Virus (AAV) Life Cycle
Nina DiPrimio, Aravind Asokan and Richard J. Samulski
Mol Ther 13: S43-S43; doi:10.1016/j.ymthe.2006.08.124
105. Interactions between Modified AAV Vectors and Alternative Cell Surface Receptors Define Intercellular Trafficking Pathways and Tranduction in Human Vascular Endothelial Cells
Matthew D. Stachler and Jeffrey S. Bartlett
Mol Ther 13: S43-S43; doi:10.1016/j.ymthe.2006.08.125
106. rAAV2 Traffics through Both the Late and Recycling Endosomes in a Dose-Dependent Fashion
Wei Ding, Liang N. Zhang, Charles Yeaman and John F. Engelhardt
Mol Ther 13: S44-S44; doi:10.1016/j.ymthe.2006.08.126
107. |[alpha]|2, 3 and |[alpha]|2,6 N-Linked Sialic Acid Facilitate Efficient Binding and Transduction by Adeno-Associated Virus Type 1 and 6
Zhijian Wu and R. Jude Samulski
Mol Ther 13: S44-S44; doi:10.1016/j.ymthe.2006.08.127
108. Study of an AAV-8 Capsid Mutant with Direct Heparin Binding Capability but Reduced Efficiency in Liver-Targeted Transduction
Xuan Shen, Hui Xu, Theresa Storm and Mark A. Kay
Mol Ther 13: S44-S45; doi:10.1016/j.ymthe.2006.08.128
109. Episomal AAV Vector Genome in the Histone-Associated Chromatin Form Is Capable of Superior Transcription with HDAC Inhibitor
Takashi Okada, Ryosuke Uchibori, Mayumi Iwata-Okada, Mutsuko Nonaka-Sarukawa, Takayuki Ito, Hiroaki Mizukami, Akihiro Kume and Keiya Ozawa
Mol Ther 13: S45-S45; doi:10.1016/j.ymthe.2006.08.129
110. Investigation of Biochemical Factors That May Influence Immunogencity of AAV2 Vectors
Bernd Hauck, Federico Mingozzi, Valder Arruda, Katherine A. High and J. Fraser Wright
Mol Ther 13: S45-S45; doi:10.1016/j.ymthe.2006.08.130
111. Post-Transcriptional Gene Silencing of Alpha-1 Antitrypsin by Small Interfering RNAs (siRNA)
Pedro E. Cruz, Alexandra Golant and Terence R. Flotte
Mol Ther 13: S45-S46; doi:10.1016/j.ymthe.2006.08.131
112. Overexpression of the Coxsackie Adenovirus Receptor (CAR) Gene Influences AAV2 Transduction in Human Trabecular Meshwork Cells
Guorong Li and Teresa Borras
Mol Ther 13: S46-S46; doi:10.1016/j.ymthe.2006.08.132
113. Transduction of Neural Cells in Primate Brain Using Adeno-Associated Virus (AAV) Serotypes 2 and 5
Eleni A. Markakis, Csaba Leranth, Jeremy Bober, R. Jude Samulski, J.E. Rabinowitz, X. Zhou, Kenneth Vives and D. Eugene Redmond Jr
Mol Ther 13: S46-S47; doi:10.1016/j.ymthe.2006.08.133
114. Revisiting rAAV Vector Integration in scid Mice: DNA-PKcs Deficiency Does Not Substantially Increase Integration Frequency in Hepatic and Non-Hepatic Tissues In Vivo
Katsuya Inagaki, Theresa A. Storm, Mark A. Kay and Hiroyuki Nakai
Mol Ther 13: S47-S47; doi:10.1016/j.ymthe.2006.08.134
115. Whole Genome Analysis Shows That AAV Integrates at Chromosome 19 AAV-S1 Sites and Other Chromosomal Sites That Frequently Share GGTC Micro-Homology with the AAV P5 Promoter
Horace R. Drew III, Linda J. Lockett and Gerald W. Both
Mol Ther 13: S47-S47; doi:10.1016/j.ymthe.2006.08.135
116. The Proposed AAV Serotypes 10 and 11 Serologically Cross-React with AAV8 and AAV4
Luk H. Vandenberghe, James R. Miller, Gaung-Ping Gao, Roberto Calcedo and James M. Wilson
Mol Ther 13: S47-S48; doi:10.1016/j.ymthe.2006.08.136
117. HSPG Binding Properties of Adeno-Associated Virus Retargeting Mutants and Consequences for Their In Vivo Tropism
Daniela Goldnau, Luca Perabo, Kathryn White, Jan Endell, Sibille Humme, Lorraine Work, Hanna Jannicki, Michael Hallek, Andrew H. Baker and Hildegard Buening
Mol Ther 13: S48-S48; doi:10.1016/j.ymthe.2006.08.137
118. In Vivo Tracking of Long Term Gene Expression of AAV1 Using Fluorescence Imaging System
Ryuichi Yoneyama, Julieta Palomeque, Kozo Hoshino, Alec M. De Grand, John V. Frangioni and Roger Joseph Hajjar
Mol Ther 13: S48-S49; doi:10.1016/j.ymthe.2006.08.138
119. Intrahepatic Injection of rAAV Serotype 2 Overcomes Gender-Related Differences on Liver Transduction
Kepa Berraondo, Julien S. Crettaz, Laura Ochoa, Astrid Paneda, Jesus Prieto, Inaki F. Troconiz and Gloria Gonz|[aacute]|lez-Aseguinolaza
Mol Ther 13: S49-S49; doi:10.1016/j.ymthe.2006.08.139
120. Tropism and Toxicity of Adeno-Associated Viral Vector Serotypes on Neurons and Glia In Vitro
Doug B. Howard, Kathleen Powers, Barry J. Hoffer, Yun Wang and Brandon K. Harvey
Mol Ther 13: S49-S49; doi:10.1016/j.ymthe.2006.08.140
121. Adenovirus Titers Determined by Quantitative Real-Time PCR Correlate with Infectious Titers
Maria A. Thomas, Peter Krajcsi, Drew L. Lichtenstein, Ann E. Tollefson and William S.M. Wold
Mol Ther 13: S49-S50; doi:10.1016/j.ymthe.2006.08.142
122. Generation of a Family of Ad5 Mutants with Slowed Packaging Kinetics but Non-Affected Packaging Efficiency
Raul Alba, Patrick Hearing, Assumpcio Bosch and Miguel Chillon
Mol Ther 13: S50-S50; doi:10.1016/j.ymthe.2006.08.143
123. Cysteine Protease Inactivation of Adenovirus Is Responsible for Thermal Stress-Induced Adenovirus Infectivity Loss
De-Min Zhu, Donna Williams and Shilu Wu
Mol Ther 13: S50-S50; doi:10.1016/j.ymthe.2006.08.144
124. Optimizing Adenoviral-Based Vaccination by Combining an RGD-Modified Capsid with a Helper-Dependent Adenovirus
Airi Harui, Michael D. Roth and Saroj K. Basak
Mol Ther 13: S50-S51; doi:10.1016/j.ymthe.2006.08.145
125. Enhancement of Virus Mediated Gene Transfer by Polycationic Compounds
Saara Lehmusvaara, Eveliina Pasanen, Outi Rautsi, Tanja Hakkarainen, Marika Ruponen and Jarmo Wahlfors
Mol Ther 13: S51-S51; doi:10.1016/j.ymthe.2006.08.146
126. Evaluation of Replication Competent and Replication Incompetent Adenovirus-Mediated Toxicity in Human Adrenocortical Cells
Urska Matkovic, Monia Pacenti, Marta Trevisan, Giulia Masi, Luisa Barzon and Giorgio Palu
Mol Ther 13: S51-S52; doi:10.1016/j.ymthe.2006.08.147
127. Modulation of Adenoviral Vector Transduction by Hyaluronan and CD44 In Vivo
Joshua N. Mallam, Saumya Chaudhuri, Patricia Chevez-Barrios, Lalita Wadhwa, Mary Y. Hurwitz and Richard L. Hurwitz
Mol Ther 13: S52-S52; doi:10.1016/j.ymthe.2006.08.148
128. Evaluation of a CD46-Transgenic Mouse as a Model for Adenovirus Distribution and Expression
Emma Andersson, Ida Grundberg, Karin Edlund and G|[ouml]|ran Wadell
Mol Ther 13: S52-S52; doi:10.1016/j.ymthe.2006.08.149
129. Adenovirus Serotype 35 Vector-Mediated Transduction in Mouse Hematopoietic Stem Cells Isolated from Human CD46-Transgenic Mice
Fuminori Sakurai, Kenji Kawabata, Takao Hayakawa and Hiroyuki Mizuguchi
Mol Ther 13: S52-S53; doi:10.1016/j.ymthe.2006.08.150
130. Insertion of Transgenes into the E3 or L3 Region To Allow Tumor Selective Expression from Armed Oncolytic Adenoviruses
Michael Robinson, Satya Yendluri, Derek Ko, Lynda Hawkins and Karin Jooss
Mol Ther 13: S53-S53; doi:10.1016/j.ymthe.2006.08.151
131. Design and Construction of an Adenovirus Vector Containing Fiber Fibritin/Canine CD40L Fibers Directed to Canine CD40-Expressing Cells
Masaharu Nakayama, Joel N. Glasgow, Bruce F. Smith, Jing Li, Nikolay Korokhov, Natalya Belousova, Kenzaburo Tani and David T. Curiel
Mol Ther 13: S53-S53; doi:10.1016/j.ymthe.2006.08.152
132. Increased GFP Gene Delivery to Human Prostate Cancer Cells Using Trancomplementing Adenoviral Vectors
Elena E. Mitrofanova, Robert C. Unfer, Martha Carvour, Molly Thrall, Jim Higginbotham, Prem Seth and Charles Link
Mol Ther 13: S53-S54; doi:10.1016/j.ymthe.2006.08.153
133. Adenovirus-Light Chain Inhibition of Growth Hormone Release from Pituitary Adenoma Cells
Thais Federici, Qingshan Teng, Mary Garrity-Moses, Christina Krudy, Jun Yang and Nicholas M. Boulis
Mol Ther 13: S54-S54; doi:10.1016/j.ymthe.2006.08.154
134. A Mechanistic and Kinetic Model for the Inactivation of Liquid-Formulated Adenoviral Vectors by the Delayed Onset of a Rapid Period of Penton Disassociation
David Frey and Cassandra Shu
Mol Ther 13: S54-S54; doi:10.1016/j.ymthe.2006.08.155
135. Replication Competent Ad11 Vectors Possess a High Potential for Human Cells Targeted Cancer Therapy
Ya-Fang Mei and Goran Wadell
Mol Ther 13: S54-S54; doi:10.1016/j.ymthe.2006.08.156
136. The Oncolytic Adenovirus Targeting to TERT and Rb Pathway Induced Specific Cytotoxicity to Tumor Cells
Rong Cai, Wei Zhang, Aiwen Dong, Kai Chen, Songbo Qiu, Xinyuan Liu and Cheng Qian
Mol Ther 13: S55-S55; doi:10.1016/j.ymthe.2006.08.157
137. Streamlined Method for the Simultaneous Construction and Purification of Multiple Recombinant Adenoviral Vectors
Thomas P. Quinn, Marylou G. Gibson, Michael Haugwitz, Michael Phelan and Andrew A. Farmer
Mol Ther 13: S55-S55; doi:10.1016/j.ymthe.2006.08.158
138. Targeted Adenoviral Vectors Expressing Soluble TGF|[beta]|RIIFc for Breast Cancer Metastasis
Zhen-Guo Wang Wang, Amanda Pister, M.B. Zafar, Sung Kim and Prem Seth
Mol Ther 13: S55-S55; doi:10.1016/j.ymthe.2006.08.159
139. Manufacture of a Replication-Selective and Enhanced-Lytic Adenovirus Vector
Moria Artlip, Sawako Ishikawa, Scott Jendrek and Dexter T.K. Poon
Mol Ther 13: S55-S55; doi:10.1016/j.ymthe.2006.08.160
140. Enhanced Cell Killing Effect of E1 Modified Adenoviruses Expressing HSV-TK Suicide Gene
Oh-Joon Kwon, Dong Hyun Ko, Jing Hwa Huang, Il-Kyu Choi, Sung-Mi Jung, Joo-Hang Kim, Byoung Chul Cho and Chae-Ok Yun
Mol Ther 13: S56-S56; doi:10.1016/j.ymthe.2006.08.161
141. Ovarian Cancer-Specific Gene Therapy by Oncolytic Adenovirus
Katsuyuki Hamada
Mol Ther 13: S56-S56; doi:10.1016/j.ymthe.2006.08.162
142. pFex: A Highly Efficient Adenoviral Vector System for Fiber Gene Modification
Shawn E. Lupold, Tarana A. Kudrolli, Wasim H. Chowdhurry and Ronald Rodriguez
Mol Ther 13: S56-S56; doi:10.1016/j.ymthe.2006.08.163
143. Development of Telomerase Specific Antineoplastic Adenovirus Telomelysin (OBP-301): Establishment of Useful Assay and Assessment for Antitumor Activity
Yuuri Hashimoto, Fuminori Teraishi, Yuichi Watanabe, Shunsuke Kagawa, Hitoshi Kawamura, Katsuyuki Nagai, Noriaki Tanaka, Yasuo Urata and Toshiyoshi Fujiwara
Mol Ther 13: S56-S56; doi:10.1016/j.ymthe.2006.08.164
144. Magnetically Responsive Nanoparticles Enhance Adenoviral Gene Delivery in Cultured Smooth Muscle Cells
Michael Chorny, Ilia Fishbein, Ivan Alferiev, Origene Nyanguile and Robert J. Levy
Mol Ther 13: S57-S57; doi:10.1016/j.ymthe.2006.08.165
145. Detection of the Primary Destabilizing Modification of Liquid-Formulated Adenoviral Vectors by Anion-Exchange High Performance Liquid Chromatography
Cassandra Shu and David Frey
Mol Ther 13: S57-S57; doi:10.1016/j.ymthe.2006.08.166
146. Development of Modified Adenovirus Vectors with Reduced Innate Immune Response
Hiroyuki Mizuguchi, Naoya Koizumi, Kenji Kawabata, Fuminori Sakurai and Takao Hayakawa
Mol Ther 13: S57-S58; doi:10.1016/j.ymthe.2006.08.167
147. Effective Gene Transfer to Human Glioma Cells Using High Capacity Adenoviral Vectors: Human Glioma Cells Express Substantial Levels of CAR and Integrin Adenoviral Co-Receptors
Marianela Candolfi, James F. Curtin, Weidong Xiong, Kurt M. Kroeger, Chunyan Liu, Altan Rentsendorj, Hasmik Agadjanian, Lali Medina-Kauwe, Philip Ng, Donna Palmer, Pedro R. Lowenstein and Maria G. Castro
Mol Ther 13: S58-S58; doi:10.1016/j.ymthe.2006.08.168
148. Characterisation of a Chimpanzee Adenovirus That Is Highly Infectious to Human Low-Passage Glioma Cells
Johan Skog, Emma Andersson, Karin Edlund, Ya-Fang Mei and G|[ouml]|ran Wadell
Mol Ther 13: S58-S58; doi:10.1016/j.ymthe.2006.08.169
149. Coxsackie and Adenovirus Receptor Binding Ablation Reduces Adenovirus Liver Tropism and Toxicity
Minjung Kim, A-Rum Yoon, Ji Young Yoo, Min-Ju Kim, Yoon-A Kang, Joo-Hang Kim and Chae-Ok Yun
Mol Ther 13: S58-S59; doi:10.1016/j.ymthe.2006.08.170
150. Metabolically Biotinylated Helper Dependent Adenovirus: A New and Rapid Approach for Targeting of High-Capacity Adenoviral Vector
Vincenzo Cerullo, Michael P. Seiler, Christopher Clarke, Aylet Erez, Michael A. Barry and Brendan Lee
Mol Ther 13: S59-S59; doi:10.1016/j.ymthe.2006.08.171
151. Treatment of Experimental Schwannomas with HSV Recombinant and Amplicon Vectors
Shilpa Prabhakar, Shanta Messerli, Samuel Rabkin, Robert Martuza and Xandra O. Breakefield
Mol Ther 13: S59-S59; doi:10.1016/j.ymthe.2006.08.174
152. Comparable Protection of Human T-Cells from High Dose Challenges of HIV-1 Using Gutless and Non-Gutless rSV40 Vectors Carrying Anti-Integrase scFv: Implications for Gene Therapy
Elena I. Marusich and David S. Strayer
Mol Ther 13: S59-S60; doi:10.1016/j.ymthe.2006.08.175
153. A Novel Gene Expression System Using Human Artificial Chromosome-HSV-1 Vectors
Daniela Moralli, Kirsty Simpson, Richard Wade-Martins and Zoia Larin Monaco
Mol Ther 13: S60-S60; doi:10.1016/j.ymthe.2006.08.176
154. Tetracycline-Inducible HSV Amplicon Vectors with Expanded Range of Gene Expression Regulation
Laryssa A. Comer, Juliet L. Fernandez, Sara M. Camp, Jessica C. Tebbets, Xandra O. Breakefield and Miguel Sena-Esteves
Mol Ther 13: S60-S60; doi:10.1016/j.ymthe.2006.08.177
155. Soluble HVEM Mediates Herpes Simplex Virus 1 (HSV-1) Infection of gD Receptor-Negative Cells
Hyunjung Baek, June-young Kyoung, Juhee Park, Kee-ho Lee, William F. Goins, Justus B. Cohen, Joseph C. Glorioso and Heechung Kwon
Mol Ther 13: S61-S61; doi:10.1016/j.ymthe.2006.08.178
156. Rapid Methods of Engineering HSV Amplicon Vectors
Kazue Kasai and Yoshinaga Saeki
Mol Ther 13: S61-S61; doi:10.1016/j.ymthe.2006.08.179
157. A Mutant Type 2 Herpes Simplex Virus Deleted for the Protein Kinase Domain of the ICP10 Gene Is a Potent Oncolytic Virus
Xinping Fu, Lihua Tao and Xiaoliu Zhang
Mol Ther 13: S61-S62; doi:10.1016/j.ymthe.2006.08.180
158. Real-Time Visualization of Neuronal Differentiation and Neurite Projection Using an Indicator HSV Amplicon Vector
Shigeru Tanaka, Kazue Kasai, E. Antonio Chiocca and Yoshinaga Saeki
Mol Ther 13: S61-S62; doi:10.1016/j.ymthe.2006.08.181
159. Novel Oncolytic HSV Armed with Platelet Factor 4, an Antiangiogenic Agent, Shows Enhanced Efficacy
Ta-Chiang Liu, Tingguo Zhang, Hiroshi Fukuhara, Toshi Kuroda, Tomoki Todo, Robert L. Martuza, Samuel D. Rabkin and Andreas Kurtz
Mol Ther 13: S62-S62; doi:10.1016/j.ymthe.2006.08.182
160. Innate Immune Responses to Viral Vectors Are Modulated by Complement Inhibitors in an Ex Vivo Model Using Whole Human Blood
Lindsay J. Stanbridge, Graciela Elgue, Javier Sanchez, Vincent Dussupt, Lucy C. Hudson, John D. Lambris, Thomas Totterman, Norman J. Maitland and Bo Nilsson
Mol Ther 13: S62-S63; doi:10.1016/j.ymthe.2006.08.183
161. Truncated Vesicular Stomatitis Virus G-Protein Improves Baculovirus Transduction Efficiency In Vitro and In Vitro
Minna U. Kaikkonen, Jani K. Raty, Kari J. Airenne, Thomas Wirth, Tommi Heikura and Seppo Yla-Herttuala
Mol Ther 13: S63-S63; doi:10.1016/j.ymthe.2006.08.184
162. Bioluminescence Imaging of a Tetanus Toxin C-Terminal Fusion Protein after Vector Delivery
Lisa Pike and Sam Wang
Mol Ther 13: S63-S63; doi:10.1016/j.ymthe.2006.08.185
163. Baculovirus-Mediated Gene Transfer in New Zealand White Rabbit Skeletal Muscle
Tommi T. Heikura, Miia M. Roschier, Anssi J. Mahonen, Hanna P. Lesch, Tuomas T. Rissanen, Olli H. Laitinen, Kari J. Airenne and Seppo Yla-Herttuala
Mol Ther 13: S63-S63; doi:10.1016/j.ymthe.2006.08.186
164. HSV-1 Vector-Based Assay To Identify Inhibitors of the Vanilloid Receptor
Rahul Srinivasan, Darren Wolfe, Shaohua Huang, David Krisky, Adrian Sculptoreanu, Peter A. Friedman, William C. de Groat and Joseph C. Glorioso
Mol Ther 13: S63-S64; doi:10.1016/j.ymthe.2006.08.187
165. Enhanced Baculovirus-Mediated Transduction of Human Cancer Cells by Tumor-Homing Peptides
Anna R. Makela, Heli Matilainen, Daniel White and Christian Oker-Blom
Mol Ther 13: S64-S64; doi:10.1016/j.ymthe.2006.08.188
166. OncoVEX: A Family of Oncolytic Herpes Simplex Viruses Optimised for Therapeutic Use
Robert S. Coffin, Binlei Liu, Han Ziqun, Magdalena Assenberg, Suzanne Thomas, Jennifer Hu and Guy Simpson
Mol Ther 13: S64-S64; doi:10.1016/j.ymthe.2006.08.189
167. Polyethyleneimines as Vehicles for Oral Gene Delivery
Eytan A. Klausner and Kam W. Leong
Mol Ther 13: S64-S65; doi:10.1016/j.ymthe.2006.08.191
168. Peptide Aldehyde Inhibitors of the Proteasome as Improved Gene Transfer Agents
Molly E. Martin, Ji-Seon Kim and Kevin G. Rice
Mol Ther 13: S65-S65; doi:10.1016/j.ymthe.2006.08.192
169. Patterned Substrate-Mediated DNA Delivery Using Soft Lithography for Neural Tissue Engineering
Tiffany L. Houchin and Lonnie D. Shea
Mol Ther 13: S65-S66; doi:10.1016/j.ymthe.2006.08.193
170. Transfected Cell Arrays for Assessment of Estrogen Receptor Activation in Breast Cancer Cells
Angela K. Pannier, Zain Bengali, Eric A. Ariazi, V. Craig Jordan and Lonnie D. Shea
Mol Ther 13: S66-S66; doi:10.1016/j.ymthe.2006.08.194
171. PEG-b-PPA/DNA Micelles for Liver Targeted-Gene Delivery
Xuan Jiang, Hui Dai, Kam W. Leong and Hai-Quan Mao
Mol Ther 13: S66-S66; doi:10.1016/j.ymthe.2006.08.195
172. Spatially-Controlled Delivery of Cyclodextrin-Based Polyplexes from Solid Surfaces
In-Kyu Park, Horst A. von Recum, Shaoyi Jiang and Suzie H. Pun
Mol Ther 13: S67-S67; doi:10.1016/j.ymthe.2006.08.196
173. Novel Cell-Specific Gene Delivery for Tumors Using a Drug or Gene Delivery System Based on Responses to Intracellular Signals (D-RECS) Concept
Yoshiki Katayama, Jeong Hun Kang, Daisuke Asai, Takeshi Mori and Takuro Niidome
Mol Ther 13: S67-S67; doi:10.1016/j.ymthe.2006.08.197
174. Chloroquine and Chloroquine Analogues in Non-Viral Delivery
Jianjun Cheng, Ryan Zeidan, Swaroop Mishra, Aijie Liu, Suzie Pun, Greg Jensen, Nathalie Bellocq, Rajan Kulkarni and Mark E. Davis
Mol Ther 13: S67-S68; doi:10.1016/j.ymthe.2006.08.198
175. Delivery Via Non-Viral Options to the Auditory Structures
Mark J. Praetorius, Christoph Klingmann, Douglas E. Brough, Peter K. Plinkert and Hinrich Staecker
Mol Ther 13: S68-S68; doi:10.1016/j.ymthe.2006.08.199
176. An Inhibitor of Fumarylacetoacetate Hydrolase (Fah) for Selection of Transplanted Hepatocytes and Gene Correction In Vivo
Karsten Wursthorn, John F. Witte, R.L. Bateman, Milton Finegold, Ronald W. McClard and Markus Grompe
Mol Ther 13: S68-S68; doi:10.1016/j.ymthe.2006.08.200
177. A Novel Class of Cationic Amphiphiles for Airway Gene Delivery
Keun-Sik Kim, Qun Li, Takeshi Suda and Dexi Liu
Mol Ther 13: S68-S69; doi:10.1016/j.ymthe.2006.08.201
178. Structure-Activity Relationships in a Library of Pyridinium Non-Viral Vectors for Gene Delivery
Marc A. Ilies, Betty H. Johnson, Aaron Miller, William A. Seitz, E. Brad Thompson and Alexandru T. Balaban
Mol Ther 13: S69-S69; doi:10.1016/j.ymthe.2006.08.202
179. In Vivo Delivery of DNA or siRNA Formulated into Nanoparticles with Linear PEI
Anne-Laure Bolcato-Bellemin, Marie-Elise Bonnet and Patrick Erbacher
Mol Ther 13: S69-S69; doi:10.1016/j.ymthe.2006.08.203
180. Transfection Efficiency of Albumin-Containing DNA/Polyethylenimine Complexes in Primary Human Respiratory Epithelial Cells and In Vivo in the Murine Airways
Sante Di Gioia, Joanna Rejman, Salvatore Carrabino, Elena Copreni, Lucia Palmieri and Massimo Conese
Mol Ther 13: S70-S70; doi:10.1016/j.ymthe.2006.08.204
181. Quantitative Evaluation of Long Term Gene Expression In Vivo after Delivery of Polyethylenimine-Conjugated Sleeping Beauty Transposon DNA
Kelly M. Podetz-Pedersen, Jason B. Bell, Terry W. Steele, Joel L. Frandsen, Thomas W. Shier, R. Scott McIvor and Perry B. Hackett
Mol Ther 13: S70-S70; doi:10.1016/j.ymthe.2006.08.205
182. Branched Chitosan Oligomers Enhance Gene Delivery In Vitro and after Lung Administration In Vivo
Mohamed M. Issa, Magnus K|[ouml]|ping-H|[ouml]|gg|[aring]|rd, Kristoffer Tommeraas, Kjell M. V|[aring]|rum, Bj|[oslash]|rn E. Christensen, Olav Smids|[oslash]|rd and Per Artursson
Mol Ther 13: S70-S71; doi:10.1016/j.ymthe.2006.08.206
183. Targeting of Muscle Cells with Functionalised Lipid Particles
Harald Heider, Sandro Rusconi and Denis Bron
Mol Ther 13: S71-S71; doi:10.1016/j.ymthe.2006.08.207
184. Novel Cationic Multivalent Lipids Show Improved Delivery of siRNA and DNA
Nathan F. Bouxsein, Kai K. Ewert, Christopher S. McAllister, Heather M. Evans, Charles E. Samuel and Cyrus R. Safinya
Mol Ther 13: S71-S71; doi:10.1016/j.ymthe.2006.08.208
185. Structural Advantage of Dendritic poly(L- lysine) in Gene Delivery In Vitro and In Vivo
Takuro Niidome, Masato Yamagata, Takayuki Iida, Takahito Kawano, Kouhei Shiba and Yoshiki Katayama
Mol Ther 13: S72-S72; doi:10.1016/j.ymthe.2006.08.209
186. Efficient In Vivo Gene Expression by DNA/ Polycation/Polyanion Ternary Complexses
Tomoko Ito, Keiko Abe, Chieko Yoshihara, Naoko Iida Tanaka and Yoshiyuki Koyama
Mol Ther 13: S72-S73; doi:10.1016/j.ymthe.2006.08.210
187. Modular Cationic Peptides as Gene Delivery Agents
Rukkumani Rajagopalan, Jennifer Xavier, Nalam M. Rao and Vijaya Gopal
Mol Ther 13: S73-S73; doi:10.1016/j.ymthe.2006.08.211
188. Internalization of Novel Delivery Vector TAT-Streptavidin into Human Cells
Johanna Rinne, Brian Albarran, Juulia Jylh|[auml]|v|[auml]|, Teemu O. Ihalainen, Pasi Kankaanp|[auml]||[auml]|, Vesa P. Hyt|[ouml]|nen, Patrick S. Stayton, Markku S. Kulomaa and Maija Vihinen-Ranta
Mol Ther 13: S73-S73; doi:10.1016/j.ymthe.2006.08.212
189. Enhanced Nuclear Import and Transfection Efficiency by Disaccharide-Modified PEIs
Takeshi Nagasaki, Toshiki Shiga, Tomomi Jinta and Seiji Shinkai
Mol Ther 13: S73-S74; doi:10.1016/j.ymthe.2006.08.213
190. Gene Delivery without Nonspecific Biological Response: Comprehensive Analysis of Cell Bioactivity Using a Novel Cationic Polymer-Based System
Kayo Masago, Keiji Itaka, Nobuhiro Nishiyama, Shigeto Fukushima and Kazunori Kataoka
Mol Ther 13: S74-S74; doi:10.1016/j.ymthe.2006.08.214
191. Design, Synthesis, and Characterization of a New Class of Quaternary Ammonium Gemini Amphiphiles for Gene Delivery
Qun Li, Guisheng Zhang, Wei Xu and Dexi Liu
Mol Ther 13: S74-S74; doi:10.1016/j.ymthe.2006.08.215
192. RGD- Functionalised Liposome for Tumour Targeting
Jianmeizi (May) Chen, Ayesha Ahmad, Andrew D. Miller, Michael Keller, Eric Perouzel and Michael R. Jorgensen
Mol Ther 13: S74-S75; doi:10.1016/j.ymthe.2006.08.216
193. Gene Transfection Using Inorganic Particle/PVA/DNA Complexes Prepared by Ultra High Pressure Technology
Tsuyoshi Kimura, Kwangoo Nam, Sihngo Mutsuo, Hidekazu Yoshizawa, Masahiro Okada, Tsutomu Furuzono, Toshiya Fujisato and Akio Kishida
Mol Ther 13: S75-S75; doi:10.1016/j.ymthe.2006.08.217
194. Development of Novel DNA Formulations Based on Polymers and Cyclodextrin for Gene Delivery to the Muscle
Caroline Roques, Andr|[eacute]| Salmon, Marc Y. Fiszman, Elias Fattal and Yves Fromes
Mol Ther 13: S75-S76; doi:10.1016/j.ymthe.2006.08.218
195. Tat Peptide Conjugates of Low Molecular Weight Polyethylenimine as Effective Non-Viral Gene Delivery Vectors
Shu Wang
Mol Ther 13: S76-S76; doi:10.1016/j.ymthe.2006.08.219
196. Genetic Manipulation of Dendritic Cells through the Use of Immunolipoplexes To Induce T Cell-Specific Tolerance In Vivo
Peng H. Tan, Robert I. Lechler, Giovanna Lombardi and Andrew J.T. George
Mol Ther 13: S76-S76; doi:10.1016/j.ymthe.2006.08.220
197. Development of Chitosan Nanoparticles for Gene Delivery System
Zhi-Hong Yang, Toshinori Sato and Yoshiyuki Koyama
Mol Ther 13: S76-S77; doi:10.1016/j.ymthe.2006.08.221
198. In Vitro and In Vivo Gene-Transferring Characteristics of Novel Cationic Lipids, DMKD(O,O|[prime]|-dimyristyl-N-lysyl aspartate) and DMKE(O,O|[prime]|-dimyristyl-N-lysyl Glutamate)
Hong Sung Kim, In Ho Song, Jong Chul Kim, Eun Jung Kim, Yeon Kyung Lee, Jung Seok Kim, Kyung Hye Koo, Doo Ok Jang and Yong Serk Park
Mol Ther 13: S77-S77; doi:10.1016/j.ymthe.2006.08.222
199. Plasmid DNA Delivery by Nanoparticule Loaded Coronary Stent
Cunxian Song, Xu Jin, Dunwan Zhu, Chao Zhang, Hongfan Sun, Linhua Zhang and Kangde Yao
Mol Ther 13: S77-S78; doi:10.1016/j.ymthe.2006.08.223
200. A Novel Non-Viral Polymer for Plasmid Delivery to Bone Marrow Stromal Cells (BMSC)
Basak A. Clements, Vanessa Incani, Cezary Kucharski, Afsaneh Lavasanifar and Hasan Uludag
Mol Ther 13: S78-S78; doi:10.1016/j.ymthe.2006.08.224
201. Selective Targeting of Nucleic Acid Nanoparticles to Hepatocytes In Vivo
Darren H. Wakefield, So Wong, David B. Rozema, Jason J. Klein and Jon A. Wolff
Mol Ther 13: S78-S78; doi:10.1016/j.ymthe.2006.08.225
202. Effect of Modification with Lipophilic Fragments and Inclusion of Endosomolytic Peptide on Transfection Efficiency Mediated by Lysine Dendrimers
Anna A. Egorova, Polina L. Il'ina, Anton V. Kiselev, Aleksandre N. Baranov, Irina I. Tarasenko, Gennadii P. Vlasov and Vladislav S. Baranov
Mol Ther 13: S78-S78; doi:10.1016/j.ymthe.2006.08.226
203. Salt Conditions during Polyplex Formation Significantly Alters Transfection
Qixin Leng, Jason Kahn, Jingsong Zhu, Puthapparampil Scaria and Archibald J. Mixson
Mol Ther 13: S79-S79; doi:10.1016/j.ymthe.2006.08.227
204. Novel Gene Transduction Technology by Credia TF
Motoyoshi Tanaka, Madoka Tonosaki, Masafumi Umekage, Tomio Konaka, Ikeda Hisafumi and Hirotsugu Uemura
Mol Ther 13: S79-S79; doi:10.1016/j.ymthe.2006.08.228
205. AAV-Mediated Gene Transfer to Muscle and Liver of MPS VI Animal Models
Alessandra Tessitore, Armida Faella, Fabiana Parisi, Mark Haskins and Alberto Auricchio
Mol Ther 13: S79-S79; doi:10.1016/j.ymthe.2006.08.230
206. Frequency and Analysis of Liver Tumors in AAV-Treated B6C3F1 Hybrid Mice
Peter L. Bell, A. David Moscioni, Robert J. McCarter, Di Wu, Guang-Ping Gao, Albert Hoang, Julio San Miguel, Xun Sun, Nelson Wivel, Steven E. Raper, Emma E. Furth, Mark L. Batshaw and James M. Wilson
Mol Ther 13: S80-S80; doi:10.1016/j.ymthe.2006.08.231
207. Long-Term Therapy for PKU in Mice by rAAV Pseudotype 8 Gene Transfer to Liver
Alexandre Rebuffat, Zhaobing Ding, Panco Georgiev and Beat Thony
Mol Ther 13: S80-S80; doi:10.1016/j.ymthe.2006.08.232
208. Sleeping Beauty Transposon-Mediated Long-Term |[alpha]|-L-iduronidase Expression and Correction of Lysosomal Pathology in the Murine Model of Mucopolysaccharidosis (MPS) Type I
Elena L. Aronovich, Jason B. Bell, Lalitha R. Belur, Roland Gunther, Brenda Koniar, David C.C. Erickson, Patricia A. Schachern, R. Scott McIvor, Chester B. Whitley and Perry B. Hackett
Mol Ther 13: S80-S81; doi:10.1016/j.ymthe.2006.08.233
209. Correction of Hunter Syndrome in the MPSII Mouse Model by AAV2/8-Mediated Gene Delivery
Monica Cardone, Vinicia Assunta Polito, Stefano Pepe, Linda Mann, Alessandra D'Azzo, Alberto Auricchio, Andrea Ballabio and Maria Pia Cosma
Mol Ther 13: S81-S81; doi:10.1016/j.ymthe.2006.08.234
210. Permanent Correction of Leptin Deficiency through Cutaneous Gene Therapy. Lentivirus but Not Retrovirus-Transduced Human Keratinocyte Orthotopic Grafts Achieve Therapeutic Systemic Leptin Levels
Laura Rico, Isabel Mirones, Blanca Duarte, Almudena Holguin, Antonio Bernad, Marcela Del Rio and Fernando Larcher
Mol Ther 13: S81-S81; doi:10.1016/j.ymthe.2006.08.235
211. Development of Helper-Dependent Adenovirus (HDAd) Vectors for Gene Therapy in the Mouse Model for Glycogen Storage Disease Type Ia (GSD-Ia)
Dwight D. Koeberl, Lopamudra Banerjee, Baodong Sun, Andrew Bird, Y.T. Chen, Kazuhiro Hiro and Lawrence Chan
Mol Ther 13: S81-S82; doi:10.1016/j.ymthe.2006.08.236
212. Delivery of Galactocerebrosidase Activity to the Peripheral Nervous System of Mice with Globoid Cell Leukodystrophy (Krabbe Disease) by Intramuscular Injection
Mohammad A. Rafi, Han Zhi Rao, Paola Luzi, Mark T. Curtis and David A. Wenger
Mol Ther 13: S82-S82; doi:10.1016/j.ymthe.2006.08.237
213. Improving the Therapeutic Index of Helper-Dependent Adenoviral Vector for Crigler-Najjar Gene Therapy
David Dimmock, Nicola Brunetti-Pierri, Viraj Mane, Donna Palmer, Arthur Beaudet and Philip Ng
Mol Ther 13: S82-S82; doi:10.1016/j.ymthe.2006.08.238
214. Dominant-Negative Interference in the Pahenu2 Mouse: Modified Forms of PAH
Andreas Zori, Dawn D. Yang, Jon-Michael Knapp, Catherine E. Charron, Jennifer E. Embury, Stacy L. Porvasnik and Philip J. Laipis
Mol Ther 13: S82-S83; doi:10.1016/j.ymthe.2006.08.239
215. Treating Hypoparathyroidism through Regulated Expression of Parathyroid Hormone in Skeletal Muscle
Maja Z. Salva and Stephen D. Hauschka
Mol Ther 13: S83-S83; doi:10.1016/j.ymthe.2006.08.240
216. Long Term Portal Vein Administration of AAV-WPRE Vector Results in Increased Incidence of Neoplastic Disease and Hepatic Pathology
Jennifer E. Embury, Catherine C. Charron, Amy E. Poirier, Andreas Zori, Russ Carmichael, Terry R. Flotte and Philip J. Laipis
Mol Ther 13: S83-S83; doi:10.1016/j.ymthe.2006.08.241
217. Comparison of Hepatic Vein and Peripheral Vein Delivery of an AAV2/8 Vector Encoding Human a-Galactosidase A to Rhesus Macaques
Bradley L. Hodges, Qiuming Chu, Jennifer B. Nietupski, Karen M. Ashe, Kristin M. Taylor, Robin J. Ziegler, Seng H. Cheng, John Marshall and Ronald K. Scheule
Mol Ther 13: S84-S84; doi:10.1016/j.ymthe.2006.08.242
218. Gene Therapy and Enzyme Replacement in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis
Michael Chang, David Sleat, Seng Cheng, Marco Passini, Peter Lobel and Beverly L. Davidson
Mol Ther 13: S84-S84; doi:10.1016/j.ymthe.2006.08.243
219. Persistent Correction of Hyperphenylalaninemia Following Liver-Directed, rAAV2/8-Mediated Gene Therapy for Murine Phenylketonuria (PKU)
Cary O. Harding, Melanie B. Gillingham, Elizabeth Daghighi, Andrew Bird and Dwight D. Koeberl
Mol Ther 13: S84-S84; doi:10.1016/j.ymthe.2006.08.244
220. AAV Mediated Gene Transfer of Smad7 in Different Models of Cystic Kidney Diseases
Andrea Keppler, Barbara Leuchs, Carolin Stump, Steven Dooley, Juergen Kleinschmidt and Norbert Gretz
Mol Ther 13: S85-S85; doi:10.1016/j.ymthe.2006.08.245
221. A New Retroviral Gene Therapy Approach for Cystinuria Research
Sreedhar Sagi, Marcus Picard-Maureau, Rudiger Dorries, Peter Alken, Maurice S. Michel and Thomas Knoll
Mol Ther 13: S85-S85; doi:10.1016/j.ymthe.2006.08.246
222. Aberrant Striatal Gene Expression in the Striatum of HPRT-Knockout Mouse
Shaochun Song, C. Ramana Bhasker, Ling Guo and Theodore Friedmann
Mol Ther 13: S85-S85; doi:10.1016/j.ymthe.2006.08.247
223. Proteomic Analysis of the Striatum of Wild Type and HPRT-Deficient Mouse
Ling T. Guo, Charles C. King, Shaochun Song and Theodore Friedmann
Mol Ther 13: S85-S86; doi:10.1016/j.ymthe.2006.08.248
224. Pyruvate Dehydrogenase Complex Deficiency Caused by the Ubiquitin-Proteasome System-Mediated Degradation in E1|[beta]| Subunit
Zongchao Han, Arun Srivastava and Peter Stacpoole
Mol Ther 13: S86-S86; doi:10.1016/j.ymthe.2006.08.249
225. A Novel Mechanism between Diabetes Mellitus Complications and Procalcitonin Gene Expression
Mehmet A. Soylemez, Ceyhan Sayar, Bilge Turkover, Guven Toksoy and Tulay Yardimci
Mol Ther 13: S86-S86; doi:10.1016/j.ymthe.2006.08.250
226. Effective Gene Therapy in an Authentic Mouse Model of Tay-Sachs Related Diseases
Begona Cachon-Gonzlez, Susan Wang, Robin Ziegler, Seng H. Cheng and Timothy M. Cox
Mol Ther 13: S86-S87; doi:10.1016/j.ymthe.2006.08.251
227. Sustained Correction of Hyperphenylalaninemia in Female Pahenu2 Mouse by a Self-Complementary Adeno-Associated Virus Vector
Akihiro Kume, Tsuyoshi Ogura, Takashi Matsushita, Hiroaki Mizukami, Masashi Urabe, Takashi Okada and Keiya Ozawa
Mol Ther 13: S87-S87; doi:10.1016/j.ymthe.2006.08.252
228. AAV Mediated Hypoxia-Inducible VEGF Expression and Neovascular Formation in Ischemic Pig Myocardium
Hua Su, Yerem Yeghiazarians, Andrew Lee, Yu Huang, Janice Arakawa-Hoyt, Jianqin Ye, Gina Orcino, William Growssman and Yuet W. Kan
Mol Ther 13: S87-S87; doi:10.1016/j.ymthe.2006.08.254
229. Use of rAAV Transduced Endothelial Progenitor Cells for the Treatment of Myocardial Infarction in Rat Model
Sabyasachi Sen, Juan Merchan, Jarrod Dean, Marcia Silver, Mary Gavin, Elizabeth Eaton, Tengiz Tkebuchava, Maasaki Ii, Young-Sup Yoon, Douglas W. Losordo and Ryuichi Aikawa
Mol Ther 13: S88-S88; doi:10.1016/j.ymthe.2006.08.255
230. In Vivo Fluorescence Tracking System for Cardiac Stem Cell Therapy
Kozo Hoshino, Hung Q. Ly, Irina Pomerantseva, Yoshiaki Takewa, Ryuichi Yoneyama, Yoshiaki Kawase, Alec M. DeGrande, John V. Frangioni and Roger J. Hajjar
Mol Ther 13: S88-S88; doi:10.1016/j.ymthe.2006.08.256
231. Gene Transfer of a Synthetic Pacemaker Channel into the Heart: A Novel Strategy for Biological Pacing
Yuji Kashiwakura, Hee Choel Cho, Ezana Azene and Eduardo Marb|[aacute]|n
Mol Ther 13: S89-S89; doi:10.1016/j.ymthe.2006.08.257
232. Short-Term, In Vivo Correction of VLCAD Deficiency in Mice: Steps toward a Gene Therapy for Cardiomyopathy
Tien Nguyen, Jan Daniels, Lawrence Merritt, Dietrich Matern, Jerry Vockley, Philip A. Wood and David B. Schowalter
Mol Ther 13: S89-S89; doi:10.1016/j.ymthe.2006.08.258
233. Conjugating Polymer Vector to Magnetic Nanobeads Enhances Local Gene Expression in the Heart
Wenzhong Li, Nan Ma, Leelee Ong, Alexander Kaminski, Peter Lorenz, Brigitte M. Putzer, Ren-Ke Li, Christof Stamm and Gustav Steinhoff
Mol Ther 13: S89-S89; doi:10.1016/j.ymthe.2006.08.259
234. Long Term Effects of pcDNA3-VEGF165 Intramyocardial Transfer after Experimental Myocardial Infarction in the Rat Scar Tissue Extracellular Matrix
Fabio D. Mataveli, Sang W. Han, Aline Mendes, Rose Kanashiro, Paulo Tucci, Helena B. Nader and Maria Aparecida S. Pinhal
Mol Ther 13: S90-S90; doi:10.1016/j.ymthe.2006.08.260
235. Herpes Simplex Virus Vector Mediated Heme Oxygenase Gene Therapy of Heart Ischemia-Reperfusion
William F. Goins, Arthur R. Frampton, Atsunori Nakao, Koji Tomiyama, David S. Clawson, James Wechuck, Shao-hua Huang, David M. Krisky, Justus B. Cohen, Noriko Murase and Joseph C. Glorioso
Mol Ther 13: S90-S90; doi:10.1016/j.ymthe.2006.08.261
236. Ultrasound-Targeted Microbubble Destruction Augments Cardiac AAV-Mediated Gene Transfer after Systemic Administration in Adult Rats
Oliver J. M|[uuml]|ller, Stefanie Schinkel, Hugo A. Katus, J|[uuml]|rgen A. Kleinschmidt and Raffi Bekeredjian
Mol Ther 13: S91-S91; doi:10.1016/j.ymthe.2006.08.262
237. Gene Expression Profiles in Diabetic Cardiomyopathy Following SERCA2a Gene Transfer
Djamel Lebeche, Susumu Sakata, Yuri Sakata, Naoya Sakata, Elie R. Chemaly, Miyako Takaki and Roger J. Hajjar
Mol Ther 13: S91-S91; doi:10.1016/j.ymthe.2006.08.263
238. Knock down Phospholamban To Improve Heart Function by AAV-Mediated shRNA
Xiaochun Lu, Guang Yang, Xiaoying Li and Xiaobing Wu
Mol Ther 13: S91-S92; doi:10.1016/j.ymthe.2006.08.264
239. Histological Measurement of Myocardial Infarct Area Does Not Provide a Sensitive Assessment of Infarct Size in a Mouse Chronic Infarct Model
Junya Takagawa, Yan Zhang, Richard E. Sievers, Neel K. Kapasi, Maelene L. Wong, Yerem Yeghiazarians, Randall J. Lee, William Grossman and Matthew L. Springer
Mol Ther 13: S92-S92; doi:10.1016/j.ymthe.2006.08.265
240. Hemiparkisonism Induced through Unilateral Expression of Adenovirus-Mediated Clostridial Light Chain Gene in the Substantia Nigra
Jun Yang, Qingshan Teng, Mary E. Garrity-Moses, Thais Federici, John Butler, Shearwood McClelland III and Nicholas M. Boulis
Mol Ther 13: S92-S92; doi:10.1016/j.ymthe.2006.08.267
241. A Dose-Ranging Study of AAV-hAADC Therapy in Parkinsonian Monkeys
John R. Forsayeth, Jamie L. Eberling, Laura M. Sanftner, Zhu Zhen, Philip Pivirotto, John Bringas, Janet Cunningham and Krystof S. Bankiewicz
Mol Ther 13: S93-S93; doi:10.1016/j.ymthe.2006.08.268
242. Neuronal Specificity of |[alpha]|-Synuclein Toxicity and the Effect of Parkin Co-Expression in Primates
Toru Yasuda, Masahiko Takada, Hideki Mochizuki and Yoshikuni Mizuno
Mol Ther 13: S93-S93; doi:10.1016/j.ymthe.2006.08.269
243. Control of Undesirable Effects of GDNF Delivered in the Striatum of Healthy Rats Using a Tetracycline-Inducible AAV1 Vector
Abdelwahed Chtarto, Xin Yang, Mansoor Sharifi, Olivier Bockstael, Enni Lehtonen, David Blum, Laurence Abeloos, Jean-Marie Jaspar, Thierry Velu, Jacques Brotchi, Marc Levivier and Liliane Tenenbaum
Mol Ther 13: S93-S93; doi:10.1016/j.ymthe.2006.08.270
244. New Gene Therapy for Parkinson's Disease by Down Regulation of |[alpha]|-Synuclein
Hideki Mochizuki, Hiromi Hayashita-Kinoh, Masanori Yamada and Yoshikuni Mizuno
Mol Ther 13: S93-S94; doi:10.1016/j.ymthe.2006.08.271
245. Delivery of IGF-1 in the Spinal Cord of a Mouse Model of ALS after Intraparenchymal Injection of an Adeno-Associated Vector
Christine Haenggeli, Angelo C. Lepore, Natalie Perez, Brian K. Kaspar and Jeffrey D. Rothstein
Mol Ther 13: S94-S94; doi:10.1016/j.ymthe.2006.08.272
246. Efficient Gene Transfer to Peripheral Nervous System Via Systemic Delivery of AAV Vectors
Chunping Qiao, Jianbin Li, Tong Zhu, Bing Wang, Juan Li, and Xiao Xiao
Mol Ther 13: S94-S94; doi:10.1016/j.ymthe.2006.08.273
247. Devising A|[beta]|-Specific Passive Immunization Strategies for Alzheimer's Disease Using rAAV Vector-Mediated scFv Antibody Delivery
Kelly L. Fowlkes, Michael A. Mastrangelo, Wade C. Narrow, Yona Levites, Todd E. Golde, Howard J. Federoff and William J. Bowers
Mol Ther 13: S94-S95; doi:10.1016/j.ymthe.2006.08.274
248. Revealing the Role(s) of TNF-alpha in Early Alzheimer's Disease Via rAAV-Mediated Hippocampal Gene Transfer in a Triple Transgenic Mouse Model
Michelle C. Janelsins, Michael A. Mastrangelo, Keigan M. Park, Kelly L. Fowlkes, Maria Kinsky, Wade C. Narrow, Salvatore Oddo, Frank M. LaFerla, Howard J. Federoff and William J. Bowers
Mol Ther 13: S95-S95; doi:10.1016/j.ymthe.2006.08.275
249. Fusion Intrabodies as Anti-Huntington Gene Therapy
Julie McLear, Jack Webster, Nikolas Webster and Anne Messer
Mol Ther 13: S95-S95; doi:10.1016/j.ymthe.2006.08.276
250. Protection Against Huntington's Diease Progression: AAV-Mediated Delivery of Biotherapeutics
Adrian P. Kells, Rebecca A. Henry, Stephanie M. Hughes, Richard L.M. Faull and Bronwen Connor
Mol Ther 13: S95-S96; doi:10.1016/j.ymthe.2006.08.277
251. Gene-Based Interferon-Beta Therapy for Experimental Autoimmune Encephalomyelitis
Ritika Jaini, Drew Hannaman, Justin M. Johnson, Robert M. Bernard, Cengiz Z. Altuntas, Maida M. de las Alas, Pavani Kesaraju, Alain Luxembourg, Claire F. Evans and Vincent K. Tuohy
Mol Ther 13: S96-S96; doi:10.1016/j.ymthe.2006.08.278
252. Targeted Transgene Integration of the Human ATM cDNA Mediated by HSV/AAV Hybrid Amplicon Vector
Jocelyn D. Sanford, Angelika Oehmig, Katherine F. Perry, Xandra O. Breakefield and Maria L. Cortes
Mol Ther 13: S96-S96; doi:10.1016/j.ymthe.2006.08.279
253. AAV Delivery of a Trans-Splicing RNA Re-Directs SMN2 Splicing and Results in Increased Full-Length SMN
Tristan H. Coady, Monir Shababi and Christian L. Lorson
Mol Ther 13: S97-S97; doi:10.1016/j.ymthe.2006.08.280
254. Protecting the CNS Using AntiOxidant Gene Transfer: HIV-1 Glycoprotein gp120 Induces Blood-Brain Barrier Abnormalities That May Be Prevented by rSV40 Gene Transfer of AntiOxidant Enzymes
Jean-Pierre Louboutin, Beverly A.S. Reyes, Lokesh Agrawal, Elisabeth J. van Bockstaele and David S. Strayer
Mol Ther 13: S97-S97; doi:10.1016/j.ymthe.2006.08.281
255. Preventing In Vivo Neurotoxicity Caused by HIV-1 Gp120 Using SV40 Vector Delivery of the Anti-Oxidant Enzymes Superoxide Dismutase and Glutathione Peroxidase
Lokesh Agrawal, Jean-Pierre Louboutin, Beverly A.S. Reyes, Elisabeth Van Bockstaele and David S. Strayer
Mol Ther 13: S97-S98; doi:10.1016/j.ymthe.2006.08.282
256. Novel Therapeutic Strategy for Ischemic Stroke by Bone Marrow Stromal Cells and Ex Vivo HGF and FGF2 Genes Transfer with Replication-Incompetent HSV-1 Vector
Naosuke Nonoguchi, Ming-Zhu Zhao, Naokado Ikeda, Yoshihito Miki, Daisuke Furutama, Fumiharu Kimura, Mari Dezawa, Hiroshi Funakoshi, Robert S. Coffin, Shin-ichi Miyatake and Toshihiko Kuroiwa
Mol Ther 13: S98-S98; doi:10.1016/j.ymthe.2006.08.283
257. VEGF Gene Transfered Bone Marrow Stromal Cells by Replication-Deficiet Herpes Simplex Virus Type-1 (HSV-1) Vector Can Improve the Neurological Deficits and Reduce the Infaction in Rat Ischemic Brain
Yoshihito Miki, Naosuke Nonoguchi, Naokado Ikeda, Ming-Zhu Zhao, Daisuke Furutama, Robert S. Coffin, Naosuke Nonoguchi and Shin-ichi Miyatake
Mol Ther 13: S98-S99; doi:10.1016/j.ymthe.2006.08.284
258. CNS-Directed Antioxidant Enzyme Delivery: Protecting Neurons from Oxidative Stress and Apoptosis Induced by HIV-1
Lokesh Agrawal, Jean-pierre Louboutin and David S. Strayer
Mol Ther 13: S99-S99; doi:10.1016/j.ymthe.2006.08.285
259. Plasmid DNA Encoding the Anti-Inflammatory Cytokine Gene, Interleukin-10 (IL-10) for Chronic Pain Control: Taking Advantage of Nuclear Scaffold/Matrix Attachment Regions
Erin D. Milligan, Stephen J. Langer, Travis S. Hughes, Evan M. Sloane, John H. Mahoney, Brian M. Jekich, Steven F. Maier, Leslie A. Leinwand and Linda R. Watkins
Mol Ther 13: S99-S99; doi:10.1016/j.ymthe.2006.08.286
260. ITRs Necessary for IL-10 Encoding Naked Plasmid Induced Reversal of Chronic Pain State in Rat
T.S. Hughes, S.J. Langer, E.M. Sloane, J. Mahoney, B. Jekich, K.W. Johnson, R.E. Chavez, E.D. Milligan, L.R. Watkins and L.A. Leinwand
Mol Ther 13: S100-S100; doi:10.1016/j.ymthe.2006.08.287
261. In Vivo Over-Expression of Fractalkine, a Putative Neuron-to-Glia Signal, To Characterize Underlying Mechanisms of Neuropathic Pain
Stephen J. Langer, David Busha, Erin D. Milligan, Travis S. Hughes, Julie Wieseler-Frank, Linda R. Watkins and Leslie A. Leinwand
Mol Ther 13: S100-S100; doi:10.1016/j.ymthe.2006.08.288
262. Delivery of CCL21 to Metastatic Disease Improves the Efficacy of Adoptive T Cell Therapy
Uma Thanarajasingam, Laura Sanz Alcober, Rosa Maria Diaz, Jian Qiao, Luis Sanchez-Perez, Timothy Kottke, Jill Thompson and Richard Vile
Mol Ther 13: S100-S101; doi:10.1016/j.ymthe.2006.08.316
263. Antigen-Specific and MHC-Independent Tumor Cell Lysis by Redirected Human CD4+ T Cells Grafted with an Antibody-Type Immunoreceptor
Andreas Hombach, Heike Koehler, Gunter Rappl and Hinrich Abken
Mol Ther 13: S101-S101; doi:10.1016/j.ymthe.2006.08.317
264. Immune Gene-Therapy of Cancer Using Redirected Na|[iuml]|ve or Effector Lymphocytes
Dinorah Friedmann-Morvinski, Tova Waks and Zelig Eshhar
Mol Ther 13: S101-S101; doi:10.1016/j.ymthe.2006.08.318
265. Non-Viral Delivery of Interleukin-2 and Soluble Flk-1 Inhibits Metastatic and Primary Tumor Growth in Renal Cell Carcinoma
James W. Yockman, Won Jong Kim, Chien-Wen Chang and Sung Wan Kim
Mol Ther 13: S101-S101; doi:10.1016/j.ymthe.2006.08.319
266. Gene Modification of T Antigen Presenting Cells for the Induction of Antitumor Immunity
Aaron E. Foster, Ann M. Leen, Timothy Lee, Juan Vera, Gianpietro Dotti and Cliona M. Rooney
Mol Ther 13: S101-S102; doi:10.1016/j.ymthe.2006.08.320
267. Synergistic Antitumor Effect of neu DNA Vaccine and Low Dose of Geldanamycin
Chi-Chen Lin, Meng-Chi Yen and Ming-Derg Lai
Mol Ther 13: S102-S102; doi:10.1016/j.ymthe.2006.08.321
268. CD19-Targeted Normal and CLL Patient T Cells Expanded with Beads Can Eradicate Systemic Tumors In Vivo
J. Stefanski, R. Brentjens, D. Hollyman, M. Bonyhadi, M. Sadelain and I. Rivi|[egrave]|re
Mol Ther 13: S102-S102; doi:10.1016/j.ymthe.2006.08.322
269. Integrated CD28 and 4-1BB Signals Strongly Potentiate CD8+ T Cell Mediated radication of Metastatic Prostate Cancer
Xiao-Song Zhong, Maiko Matsushita, Aurore Saudemont, Elmer Santos and Michel Sadelain
Mol Ther 13: S103-S103; doi:10.1016/j.ymthe.2006.08.323
270. The RheoSwitch|[reg]| Therapeutic System Precisely Regulates IL-2 Expression in Melanoma Cells and Supports Survival of NK Cells at the Tumor Site
Anand K. Katakam, Qin Yang, Steve Goding, Prasanna Kumar and Per H. Basse
Mol Ther 13: S103-S103; doi:10.1016/j.ymthe.2006.08.324
271. Full-Length Antibody Therapy Mediated by Adenovirus in Rodent and Non-Primate Animal Models
Wenfang Shi, Jie Chen, Minghong Jiang, Changqing Su and Qijun Qian
Mol Ther 13: S104-S104; doi:10.1016/j.ymthe.2006.08.325
272. Conversion of a Tumor-Binding Peptide Identified by Phage Display to a Functional Chimeric T-Cell Antigen Receptor
Colette R.J. Pameijer, Araceli Hamlett, Bessie Meechovet, Jamie Buckmaster, Brenda Aguilar, Christine Wright, Wen- Chung Chang, Christine E. Brown and Michael C. Jensen
Mol Ther 13: S104-S104; doi:10.1016/j.ymthe.2006.08.326
273. Immuno Gene Therapy of Feline Fibrosarcoma Using Intratumoral Magnetofection or Gene-Activated Matrices for Gene Delivery |[ndash]| Preliminary Results of a Veterinary Clinical Study
Ulrike Schillinger, Bianca Schwarz, Tina Kempf, Anika Jahnke, Cornelia Fischer, Anne Loecher, Stefanie Schlemmer, Johannes Hirschberger, Thomas Brill, Roberto Koestlin, Bernd Gaensbacher and Christian Plank
Mol Ther 13: S105-S105; doi:10.1016/j.ymthe.2006.08.327
274. Antitumor Effect of Controlled Expression of Interleukin-12 in a Murine Model of Liver Metastases
Itsaso Mauleon, Julien Crettaz, Gloria Gonzalez-Aseguinolaza, Maider Zabala, Gabriela Kramer, Stephan Kochanek, Jesus Prieto and Ruben Hernandez-Alcoceba
Mol Ther 13: S105-S105; doi:10.1016/j.ymthe.2006.08.328
275. Immunostimulatory Antigen Loaded Microparticles as Cancer Vaccines
Aliasger K. Salem, Anthony D. Sandler, George J. Weiner, Xueqing Zhang, Nicki K. Baman, Xiaoyan Zhu and Christopher E. Dahle
Mol Ther 13: S105-S105; doi:10.1016/j.ymthe.2006.08.329
276. Phase I Trial of Sequential Administration of Recombinant DNA and Adenovirus Expressing L523S Protein in Early Stage Non Small Cell Lung Cancer (NSCLC)
John Nemunaitis, Thomas Meyers, Neil Senzer, Casey Cunningham, Howard West, Eric Vallieresma, Stephen Anthony, Svetislava Vukelja, Barry Berman, Heather Tully, Beena Pappen, Stephen Sarmiento, Rosemarie Arzaga, Steven Duniho, Susan Engardt, Madeleine Meagher and Martin Cheever
Mol Ther 13: S106-S106; doi:10.1016/j.ymthe.2006.08.330
277. Clinical Evaluation of Dendritic Cell Vaccination for Patients with Recurrent Glioma: Results of a Clinical Phase I/II Trial
Ryuya Yamanaka, Junpei Homma, Naoki Yajima, Masakazu Sano and Masuhiro Takahashi
Mol Ther 13: S106-S106; doi:10.1016/j.ymthe.2006.08.331
278. Therapeutic Activities of IL-12 Gene- Modified Macrophages Embedded in Gelatin Matrix Hemostatic Sealant (FloSeal|[reg]|) in a Mouse Model of Residual Prostate Cancer
Ken-ichi Tabata, Masami Watanabe, Takefumi Satoh, Wei-hau Tian, Hongyu Wang, ElMoataz Abdel Fattah, Guang Yang, Daniel Floryk, Dov Kadmon and Timothy C. Thompson
Mol Ther 13: S106-S106; doi:10.1016/j.ymthe.2006.08.332
279. Eradication of Renal Cell Carcinoma in Mice Mediated by NK Cell Activation Using Inactivated Sendai Virus Particle (HVJ-E)
Atsuko Fujihara, Masayuki Kurooka, Tsuneharu Miki and Yasufumi Kaneda
Mol Ther 13: S107-S107; doi:10.1016/j.ymthe.2006.08.333
280. RANTES and TARC Enhanced the Antitumor Immune Effects of GM-CSF
Hiroyuki Inoue, Takafumi Nakamura, Meng Xin, Yoshito Beppu, Gaku Sakaguchi, Ryo Kurita, Hidenori Hase, Yukoh Nakazaki, Yoshikazu Yonemitsu, Koichi Takayama, Yoichi Nakanishi, Yusuke Nakamura, Shigetaka Asano and Kenzaburo Tani
Mol Ther 13: S107-S107; doi:10.1016/j.ymthe.2006.08.334
281. Adenovirus-Mediated CD40 Ligand Therapy Induces Tumor Cell Apoptosis and Systemic Immunity in the TRAMP-C2 Mouse Prostate Cancer Model
Helena Dzojic, Angelica Loskog, Thomas Totterman and Magnus Essand
Mol Ther 13: S107-S107; doi:10.1016/j.ymthe.2006.08.335
282. Antitumor Efficacy of Intravenous Administration of Oncolytic Herpes Simplex Virus Expressing Interleukin 12
Yi Guan, Yasushi Ino, Hiroshi Fukuhara and Tomoki Todo
Mol Ther 13: S108-S108; doi:10.1016/j.ymthe.2006.08.336
283. DNA Vaccination with Genes Encoding an Antigenic Protein and Fas Ligand Increased Antigen-Specific Humoral Responses
Osamu Shimozato, Ayako Sato, Kiyoko Kawamura, Quanhai Li, Guangyu Ma and Masatoshi Tagawa
Mol Ther 13: S108-S108; doi:10.1016/j.ymthe.2006.08.337
284. Reduced Lung Metastasis of Secreted Type of Substance P Gene Modified Mouse Melanoma Cells
Xianghui He, Zhixiang Zhang, Liwei Zhu, Tom C. Tsang and David T. Harris
Mol Ther 13: S108-S108; doi:10.1016/j.ymthe.2006.08.338
285. Concanavalin A That Bears Direct Cytotoxicity and Immunomodulating Activity Via Mannose-Specific Cellular Binding Has Therapeutic Effect in a Murine In Situ Hepatoma Model
Chih-Peng Chang, Ying-Tai Jin and Huan-Yao Lei
Mol Ther 13: S109-S109; doi:10.1016/j.ymthe.2006.08.339
286. Biodistribution and Cearance Following Intraperitoneal Injection of Murine Interleukin-12 Plasmid Formulated with a Novel Polymeric Delivery System
Elaine Brunhoeber, Majed Matar, Khursheed Anwer and Jason G. Fewell
Mol Ther 13: S109-S109; doi:10.1016/j.ymthe.2006.08.340
287. Safety and Toxicity Following Intraperitoneal Injection of Murine Interleukin-12 Plasmid Formulated with a Novel Polymeric Delivery System
Jason G. Fewell, Jennifer Rice, Majed Matar and Khursheed Anwer
Mol Ther 13: S109-S109; doi:10.1016/j.ymthe.2006.08.341
288. Bi-Modality Induction of TNF|[alpha]|: Neoadjuvant Chemoradiotherapy and TNFerade|[trade]| in Patients with Locally Advanced, Resectable Esophageal Carcinoma
Neil Senzer, Kenneth Chang, Stephen Swisher, Tony Reid, Ann Mauer, Amitabh Chak, Harlan Pinto and John Nemunaitis
Mol Ther 13: S110-S110; doi:10.1016/j.ymthe.2006.08.343
289. Adenoviral-Mediated p53 Gene Therapy (Advexin) in a Patient with Li-Fraumeni Syndrome with a Mixed Germ Cell Tumor: Tolerability and Response
Neil Senzer, Jeffrey Lamont and John Nemunaitis
Mol Ther 13: S110-S110; doi:10.1016/j.ymthe.2006.08.344
290. Prolegomenon to a Phase II Study of an ICP34.5/ICP47 Deleted Herpes Simplex Virus Containing the Coding Sequence for GM-CSF in Patients with Melanoma
Neil Senzer and John Nemunaitis
Mol Ther 13: S110-S110; doi:10.1016/j.ymthe.2006.08.345
291. In Vivo Characterization of Seneca Valley Virus (SVV-001), a Novel Oncolytic Picornavirus for Systemic Treatment of Patients with Solid Tumors with Neuroendocrine Features
Kevin D. Burroughs, Kristine Skele, Christian Sherk, Brian Jones, Ann-Jeanette Vasko, Laura Hales, Seshidhar R. Police and Paul L. Hallenbeck
Mol Ther 13: S111-S111; doi:10.1016/j.ymthe.2006.08.346
292. Polyethylenimine Mediated Oral Cancer Targeted PUMA Gene Delivery Suppressed Tumor Growth and Prolonged Survival
Benson Chen, Ming-Shyan Huang, Steven Yeh, Mark Y.P. Kuo and Michael Hsiao
Mol Ther 13: S111-S111; doi:10.1016/j.ymthe.2006.08.347
293. Sustained Expression of Kringle 1 Domain of Human Hepatocyte Growth Factor (HGFK1) Effectively Inhibits Angiogenesis, Growth and Metastasis of Hepatocellular Carcinoma
Zan Shen, Zhen Fan Yang, Yi Gao, Ching Chiu Liu, Samuel S. Ng, Sheung Tat Fan, Ming-liang He, Tsai-ping Li, Ren-bao Gan, Hsiang-fu Kung and Marie Chia-mi Lin
Mol Ther 13: S111-S112; doi:10.1016/j.ymthe.2006.08.348
294. The Histone Deacetylase Inhibitor FK228 Increases Histone Acetylation, Coxsackie Adenovirus Receptor Levels and Adenovirus Transgene Expression in Human LOX IMVI Melanoma Xenografts
Merrill E. Goldsmith, Kenneth Steadman, Alian Aguila, Michael C. Alley, William R. Waud, Susan Bates and Tito Fojo
Mol Ther 13: S112-S112; doi:10.1016/j.ymthe.2006.08.349
295. Effects of Sustained Anti-Angiogenic Gene Therapy in Multi-Stage Prostate Cancer in TRAMP Mice
Tatyana Isayeva, Diptiman Chanda and Selvarangan Ponnazhagan
Mol Ther 13: S112-S112; doi:10.1016/j.ymthe.2006.08.350
296. Transgene Expression and Neutralizing Antibody Production after Submandibular Gland Administration of AdhAQP1
Corinne M. Goldsmith, Changyu Zheng, Molly Vallant, Richard D. Irwin and Bruce J. Baum
Mol Ther 13: S113-S113; doi:10.1016/j.ymthe.2006.08.351
297. Safety of Repeat Intracerebral Administration of MV-CEA in Rhesus Macaques in Support of a Phase I/II Clinical Trial for Patients with Recurrent Gliomas
Rae M. Myers, Mary E. Harvey, Suzanne M. Greiner, Diane C. Soeffker, James W. Krempski, Paula J. Zollman, Steven E. Shelton, Raffel Corey, Goerss J. Stephan, Kaufmann J. Timothy, Federspiel J. Mark, Peng Kah-Whye, Russell J. Stephen and Galanis Evanthia
Mol Ther 13: S113-S113; doi:10.1016/j.ymthe.2006.08.352
298. Combination Effect of Telomerase-Specific Replication-Competent Adenovirus (Telomelysin, OBP-301) and p53 Gene Therapy in Human Non- Small Cell Lung and Colon Cancer Cells
Ryo Sakai, Fuminori Teraishi, Toru Kojima, Yoshihiro Ikeda, Masayoshi Hioki, Toshiya Fujiwara, Futoshi Uno, Shunsuke Kagawa, Yuuri Hashimoto, Yuichi Watanabe, Yasuo Urata, Noriaki Tanaka and Toshiyoshi Fujiwara
Mol Ther 13: S114-S114; doi:10.1016/j.ymthe.2006.08.353
299. In Vivo Luciferase Imaging for Analysis of Oncolytic Adenoviruses for Renal Cell Cancer
Kilian Guse, Tuuli Ranki, Tanja Hakkarainen, Martti Ala- Opas, Tommi Pisto, Merja S|[auml]|rkioja, Maria Rajecki, Anna Kanerva and Akseli Hemminki
Mol Ther 13: S114-S114; doi:10.1016/j.ymthe.2006.08.354
300. Gene Therapy for Gastric Cancer Cells Via CEA-Targeted Adv-FZ33
Toshihiro Tanaka, Jianhua Huang, Sachie Hirai, Motomu Kuroki, Masahide Kuroki, Naoki Watanabe, Kazunori Kato and Hirofumi Hamada
Mol Ther 13: S114-S115; doi:10.1016/j.ymthe.2006.08.355
301. Safe and Effective Treatment of Ovarian Cancer Models Using Targeted Adenovirus Vector Delivery and Selective Expression of Tumor Necrosis Factor
Selva R. Murugesan, Masaki Akiyama, David A. Einfeld, Thomas J. Wickham and C. Richter King
Mol Ther 13: S115-S115; doi:10.1016/j.ymthe.2006.08.356
302. Anti-Angiogenic Treatment Enhances Anti- Tumor Effects of an Oncolytic Virus in an Experimental Rat Glioma Model
Kazuhiko Kurozumi, Jennifer Cutter, William Carson, Ming Yang, Gregory Christoforidis, Antonio E. Chiocca and Balveen Kaur
Mol Ther 13: S115-S116; doi:10.1016/j.ymthe.2006.08.357
303. Enhanced Antitumor Efficacy of Telomerase-Selective Oncolytic Adenoviral Agent OBP-401 with Docetaxel: Preclinical Evaluation of Chemovirotherapy
Yoshihiro Ikeda, Toshiya Fujiwara, Shunsuke Kagawa, Masayoshi Hioki, Ryo Sakai, Toru Kojima, Yasuo Urata, Noriaki Tanaka and Toshiyoshi Fujiwara
Mol Ther 13: S116-S116; doi:10.1016/j.ymthe.2006.08.358
304. Therapeutic Efficacy of a Mesothelin Promoter-Based Conditionally Replicative Adenovirus Monitored by In Vivo Imaging of an Ovarian Cancer Model
Yuko Tsuruta, Larisa Pereboeva, Martina Breidenbach, Daniel T. Rein, Masaharu Nakayama, Gene P. Siegal and David T. Curiel
Mol Ther 13: S116-S116; doi:10.1016/j.ymthe.2006.08.359
305. Targeting the Gene and the Derived Gene- Product into Tumors
Shulin Li, Ryan Craig and Marina Torrero
Mol Ther 13: S117-S117; doi:10.1016/j.ymthe.2006.08.360
306. Imaging HSV-1 Viral Oncolysis of Colon Cancer Cells by microPET
Darshini Kuruppu, Aijun Zhu, Meixiang Yu, Anna-Liisa Brownell and Kenneth K. Tanabe
Mol Ther 13: S117-S117; doi:10.1016/j.ymthe.2006.08.361
307. Prostate Targeted TSTA Oncolytic Adenovirus
Makoto Sato, Steve Huyn, Russell Powell, Michael Carey, Sanjiv S. Gambhir and Lily Wu
Mol Ther 13: S117-S118; doi:10.1016/j.ymthe.2006.08.362
308. Valproic Acid, a Histone Deacetylase Inhibitor, Is an Antagonist for Oncolytic Adenoviral Gene Therapy
Naser Uddin Hoti, Shawn E. Lupold, Wasim Chowdhury, Jer-Tsong Hsieh and Ronald Rodriguez
Mol Ther 13: S118-S118; doi:10.1016/j.ymthe.2006.08.363
309. Oncolytic Efficacy and Enhanced Safety of Measles Virus Activated by Tumor-Secreted Matrix-Metalloproteases
Christoph Springfeld, Veronika von Messling, Marie Frenzke, Guy Ungerechts, Christian Buchholz and Roberto Cattaneo
Mol Ther 13: S118-S118; doi:10.1016/j.ymthe.2006.08.364
310. Antitumor Effect of Telomerase-Specific Virotherapy in Pleural Dissemination of Human Malignant Mesothelioma
Yuichi Watanabe, Yuuri Hashimoto, Toru Kojima, Shunsuke Kagawa, Hitoshi Kawamura, Katsuyuki Nagai, Noriaki Tanaka, Yasuo Urata and Toshiyoshi Fujiwara
Mol Ther 13: S118-S118; doi:10.1016/j.ymthe.2006.08.365
311. Target-Specific Knockdown and Enhanced Anti-Tumor Outcome by an Oncolytic Virus- Delivered Small Interfering RNA (siRNA)
Alex W. Tong, Yu-An Zhang, Shirley Samuel, Patrick Chen, Yuqiao Shen and John Nemunaitis
Mol Ther 13: S118-S119; doi:10.1016/j.ymthe.2006.08.366
312. Clearance of Helper Adenovirus by an AAV1 Clinical Vector Manufacturing Process
Barb Thorne, Paulene Quigley, Gina Nichols, David Price, Christine Moore, Kristin Parker, Tsering Sangmo, Eric Pastor, Morgan Peterson, Ryan Takeya and Richard Peluso
Mol Ther 13: S119-S119; doi:10.1016/j.ymthe.2006.08.368
313. Cell Type Specific Media Optimization for Clinical Retroviral Transduction Protocols
J. Stefanski, O. Borquez-Ojeda, T. Budak-Alpdogan, R. Kendle, M. Przybylowski, D. Hollyman, M. Sadelain and I. Rivi|[egrave]|re
Mol Ther 13: S119-S120; doi:10.1016/j.ymthe.2006.08.369
314. Developing Gene Transfer Vectors for Cancer Therapy: Identifying and Overcoming Regulatory Challenges
Rosemarie Aurigemma
Mol Ther 13: S120-S120; doi:10.1016/j.ymthe.2006.08.370
315. Identification and Control of Bacterial Contamination in an Academic Good Manufacturing Practice Facility
Timothy P. O'Connor, Neil R. Hackett, Robert G. Pergolizzi, Dolan Sondhi, Julie L. Boyer, Stephen M. Kaminsky and Ronald G. Crystal
Mol Ther 13: S120-S120; doi:10.1016/j.ymthe.2006.08.371
316. Production of Adenoviral Vectors in an Academic cGMP Facility
M.F. Medina, J. Rudy, U. Sankar, D. Chong, R. Foley and J. Gauldie
Mol Ther 13: S121-S121; doi:10.1016/j.ymthe.2006.08.372
317. Simplified Concentration and Purification of Lentivirus Pseudotypes
Robert H. Kutner, Brian DaLeo and Jakob Reiser
Mol Ther 13: S121-S121; doi:10.1016/j.ymthe.2006.08.373
318. Collaborative Development of an Effective Method To Produce Clinical RNAi Products
Sriram Ramakrishnan, Jeffrey E. Darnell, Gary Gates, Hugo L. Gonzales, Justin Miller and Henry Hebel
Mol Ther 13: S121-S121; doi:10.1016/j.ymthe.2006.08.374
319. Comparison of Serum-Free Media for Optimal Ex Vivo Transduction of Human CD34+ Cells
Joanna L. Ireland, Greg M. Podsakoff, Donald B. Kohn and Barbara C. Engel
Mol Ther 13: S122-S122; doi:10.1016/j.ymthe.2006.08.375
320. Modeling Human Brain Cancer in Transgenic E2F1 Mice
Melissa V. Olson, Kenneth D. Aldape, Gregory N. Fuller, Marta M. Alonso, Candelaria Gomez-Manzano, Johnson G. David and Fueyo Juan
Mol Ther 13: S122-S122; doi:10.1016/j.ymthe.2006.08.377
321. Sea Urchin sns Chromatin Insulator Prevents Silencing and Positional Effect Variegation of Oncoretroviral Vectors Transgene Expression in Murine Erythroid Cell Line
Danilo D'Apolito, Santina Acuto, Rosalba Di Marzo, Mariella Bagliesi, Valentina Motta, Elena Baiamonte, Roberta Calzolari, Vito Franco, Giovanni Spinelli and Aurelio Maggio
Mol Ther 13: S122-S123; doi:10.1016/j.ymthe.2006.08.378
322. Syngeneic Cotton Rat Cancer Model for Replicating Adenoviral Vectors
Jason C. Steel, Brian J. Morrison, Poonam Mannan, Gregory A. Prince, Kevin C. Yim, Brian K. Miles, Oliver Wildner and John C. Morris
Mol Ther 13: S123-S123; doi:10.1016/j.ymthe.2006.08.379
323. In Vivo Regulation of rAAV-Mediated GDNF Expression in the Rat Striatum
Corinna Burger, Emily Piercefield, Layla Sullivan, Ronald Mandel and Nicholas Muyczka
Mol Ther 13: S123-S123; doi:10.1016/j.ymthe.2006.08.380
324. Development of Bioluminescence Tomography for Three-Dimensional Real Time Imaging of Gene Expression
Nathalie Y. Toussaint, Lu Yin, Aaron Hirko, Qiang Wang, Qizhi Zhang, Huabei Jiang and Sean Sullivan
Mol Ther 13: S123-S124; doi:10.1016/j.ymthe.2006.08.381
325. In Vitro Gene Knockdown of Rat Pyruvate Dehydrogenase E1 |[alpha]| mRNA by Self- Complementary Adeno-Associated Virus-Mediated Small Interfering RNA Delivery
Zongchao Han, Marina Gorbatyuk, Alfred Lewin, Arun Srivastava and Peter Stacpoole
Mol Ther 13: S124-S124; doi:10.1016/j.ymthe.2006.08.382
326. A Versatile Tool for Conditional Gene Expression and Knockdown
Jolanta Szulc, Maciej Wiznerowicz, Friedrich Beermann, Didier Trono and Patrick Aebischer
Mol Ther 13: S124-S124; doi:10.1016/j.ymthe.2006.08.383
327. Muscle Specific and Efficient Transgene Expression Using the Fast and Slow Troponin I Promoters in Cell Culture
Marilyne Blain, Angela Kumar, Kenneth E. Hastings, George Karpati, Bernard Massie and Renald Gilbert
Mol Ther 13: S125-S125; doi:10.1016/j.ymthe.2006.08.384
328. Transcriptionally Targeted Cancer Gene Therapy for Small Cell Lung Cancer
Nina Pedersen, Thomas T. Poulsen, Mikkel W. Pedersen, Michael S. Lan, Mary B. Breslin and Hans S. Poulsen
Mol Ther 13: S125-S125; doi:10.1016/j.ymthe.2006.08.385
329. Electroporation-Mediated Delivery of Cre- Expressing Plasmids to the Lung Results in Tissue-Specific DNA Excision in Transgenic Mice
Aaron M. Miller and David A. Dean
Mol Ther 13: S125-S126; doi:10.1016/j.ymthe.2006.08.386
330. Effect of Different Inducible Minimal Promoters in the RheoSwitch|[reg]| Therapeutic System That Give Robust and Long-Term In Vivo Gene Expression
Jessica L. Seitzer, Anand Katakam, Marti A. DiPietro, Prasanna Kumar and David W. Potter
Mol Ther 13: S126-S126; doi:10.1016/j.ymthe.2006.08.387
331. Small Fragment Homologous Replacement (SFHR) Modification of Genomic HPRT Occurs in the Presence of Wild-Type p53 in Lymphoblastoid Cells
Babak Bedayat, Alireza Abdolmohammadi, Rosalie Maurisse, Jennifer Shwarz, Judi Cheung, David De Semir, Patric K O'Neill, Janice A. Nicklas and Dieter C. Gruenert
Mol Ther 13: S126-S126; doi:10.1016/j.ymthe.2006.08.388
332. Routes of Ligand Administration That Give Efficient and Robust In Vivo Induction with the RheoSwitch|[reg]| Therapeutic System
Marti A. DiPietro, Jessica L. Seitzer and David W. Potter
Mol Ther 13: S126-S127; doi:10.1016/j.ymthe.2006.08.389
333. Focused Ultrasound-Induced Transgene Activation in Skeletal Muscles
Xiaochun Lu, Georgii Sankin, John Madden and Pei Zhong
Mol Ther 13: S127-S127; doi:10.1016/j.ymthe.2006.08.390
334. A Novel Sequence-Specific Anti-Gene LNA Molecule and Its Comparison to Tail-Clamp bisPNA
Rongbin Ge, Juhana E. Heinonen, Mathias G. Svahn, Abdalla J. Mohamed, Karin E. Lundin and C.I. Edvard Smith
Mol Ther 13: S127-S127; doi:10.1016/j.ymthe.2006.08.391
335. Global Transcriptional Profiles of Murine C2C12 Myoblasts Treated with IGF-1
C. Ramana Bhasker, Shaochun Song and Theodore Friedmann
Mol Ther 13: S127-S127; doi:10.1016/j.ymthe.2006.08.392
336. Impact of Convective Flow on the Cellular Uptake and Transfection Activity of Lipoplex and Adenovirus
Takahiro Fujiwara, Hidetaka Akita, Katsuko Furukawa, Takashi Ushida and Hideyoshi Harashima
Mol Ther 13: S128-S128; doi:10.1016/j.ymthe.2006.08.393
337. Adenoviral Delivery of the RheoSwitch|[reg]| Therapeutic System to Mouse Brain and Liver
David W. Potter, Marti A. DiPietro, Jessica L. Seitzer, Anand Katakam and Prasanna Kumar
Mol Ther 13: S128-S128; doi:10.1016/j.ymthe.2006.08.394
338. Microarray Analysis of Genes Regulated during Induction of Osteogenesis by Human Lim Mineralization Protein-3 (LMP-3) in Human Mesenchymal Stem Cells
Wanda Lattanzi, Camilla Bernardini, Enrico Pola, Andrea Gambotto, Fabrizio Michetti and Paul D. Robbins
Mol Ther 13: S128-S129; doi:10.1016/j.ymthe.2006.08.395
339. FIV Lentiviral Vector Gene Transfer for Hemophilia A
C.P. Chikkanna-Gowda, Litao Xie, Yubin Kang, Melissa A. Hickey, Patrick L. Sinn, Jessica D. Goreham-Voss, Steven W. Pipe and Paul B. McCray Jr.
Mol Ther 13: S129-S129; doi:10.1016/j.ymthe.2006.08.396
340. Cellular Uptake and Subsequent Intracellular of R8-Liposomes Introduced at Low Temperature
Akitada Iwasa, Hidetaka Akita, Ikramy Khalil, Kentaro Kogure, Shiroh Futaki and Hideyoshi Harashima
Mol Ther 13: S129-S129; doi:10.1016/j.ymthe.2006.08.397
341. Lentivirus Transduction of Murine Embryonic Stem Cells with Truncated Human Low-Affinity Nerve Growth Factor Permits Efficient Purification of Genetically Modified Cells without Loss of Stem Cell Characteristics
Ralf-Harto H|[uuml]|bner, Maija Kiuru, Anja Krause, Stefano Rivella, Robert G. Pergolizzi and Ronald G. Crystal
Mol Ther 13: S130-S130; doi:10.1016/j.ymthe.2006.08.399
342. RUNX1 Increases Proliferation of Embryoid Bodies Derived from Human Embryonic Stem Cells
Jenice D'Costa, Alan D. Friedman, Elias Zambidis and Curt I. Civin
Mol Ther 13: S130-S130; doi:10.1016/j.ymthe.2006.08.400
343. Vascular Endothelial Growth Factor Prevents Bone Marrow Derived-Mesenchymal Stem Cell Senescence In Vitro
Jennifer Pons, Hua Su, Yu Huang and Y.W. Kan
Mol Ther 13: S131-S131; doi:10.1016/j.ymthe.2006.08.401
344. AAV Vector-Mediated Msx1 Gene Transfer Induces Hematopoietic Stem/Progenitor Cells in Skeletal Muscle
Masaharu Nobuyoshi, Akihiro Kume, Takashi Matsushita, Hiroaki Mizukami, Takashi Okada, Masashi Urabe, Yuichi Ohgoshi, Takashi Endo and Keiya Ozawa
Mol Ther 13: S131-S131; doi:10.1016/j.ymthe.2006.08.402
345. Hematopoietic Stem-Progenitor Cells Express CD52 mRNA and Membrane Protein
Sebastien Morisot, Robert W. Georgantas III and Curt I. Civin
Mol Ther 13: S131-S132; doi:10.1016/j.ymthe.2006.08.403
346. The ACE System, a Mammalian Artificial Chromosome Engineering Technology: Delivery and Transgene Expression in Human Adult & Embryonic Stem Cells
Sandra L. Vanderbyl, Brent Sullenbarger, Neil MacDonald, Melanie Golembiewski, Carl F. Perez, Harry C. Ledebur Jr and Larry C. Lasky
Mol Ther 13: S132-S132; doi:10.1016/j.ymthe.2006.08.404
347. Expression of the N-Formyl Peptide Receptor in Bone Marrow-Derived Human Mesenchymal Stem Cells
Anand Viswanathan, Richard G. Painter, Nicholas A. Lanson Jr and Guoshun Wang
Mol Ther 13: S132-S132; doi:10.1016/j.ymthe.2006.08.405
348. Kruppel-Like Factor 4 Regulates Proliferation of Human and Mouse Hematopoietic Stem-Progenitor Cells, but Is Not Essential for Mouse Hematopoietic Repopulation
Jonathan K. Alder, Robert W. Georgantas, Richard L. Hildreth and Curt I. Civin
Mol Ther 13: S132-S133; doi:10.1016/j.ymthe.2006.08.406
349. Pretreatment of the Esophagus with Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Complex Increases Migration and Proliferation of Marrow Stem Cell Progenitors of Esophageal Squamous Epithelium
Yunyun Niu, Michael W. Epperly and Joel S. Greenberger
Mol Ther 13: S133-S133; doi:10.1016/j.ymthe.2006.08.407
350. Ectopic Retroviral Expression of LMO2, but Not IL2R|[gamma]|, Blocks Human T-Cell Development from CD34+ Progenitor Cells: Implications for Gene Therapy
Karin Pike-Overzet, Dick de Ridder, Floor Weerkamp, Miranda R.M. Baert, Monique M. Verstegen, Steven J. Howe, Adrian J. Thrasher, Gerard Wagemaker, Jacques J.M. van Dongen and Frank J.T. Staal
Mol Ther 13: S133-S133; doi:10.1016/j.ymthe.2006.08.408
351. Inhibition of Thyroid Hormone Receptors in the Neural Stem Cells of Newborn and Adult Mice In Vivo: Consequences on Target Gene Expression
Zahra Hassani, Gladys Alfama, Jean-Christophe Fran|[ccedil]|ois, Carinne Giovannangeli and Barbara A. Demeneix
Mol Ther 13: S134-S134; doi:10.1016/j.ymthe.2006.08.409
352. CD34+ Hematopoietic Stem-Progenitor Cell MicroRNA Expression and Function: The miR Circuit Diagram of Differentiation Control
Robert W. Georgantas, Richard L. Hildreth, John Alder, Carlo Croece, George A. Calin and Curt I. Civin
Mol Ther 13: S134-S134; doi:10.1016/j.ymthe.2006.08.410
353. Biological Comparison of Mesenchymal Stem Cells Derived from Bone Marrow and Adipose Tissue
Reza Izadpanah, Cynthia Trygg, Christopher Kriedt and Bruce Bunnell
Mol Ther 13: S134-S135; doi:10.1016/j.ymthe.2006.08.411
354. Genetic Modification of Murine Stromal- Derived Cells (MSC) in Suspension Culture as a Model for the Rapid Generation of Transplantable Cytoreagents
Yung-Wei Pan, Tammy Tien Luoh and Peter Kurre
Mol Ther 13: S135-S135; doi:10.1016/j.ymthe.2006.08.412
355. A Platform for Gene Delivery to Embryonic Stem Cells Using HSV
April M. Sunyog, Darren Wolfe, James Wechuck, David Krisky, Ying Jiang and Joseph Glorioso
Mol Ther 13: S135-S135; doi:10.1016/j.ymthe.2006.08.413
356. Engineering of Cell Surface Sialic Acids for Polymeric Gene Delivery
Yihua Loo, S.-Gopalan Sampathkumar, Prabhani U. Atukorale, Kevin J. Yarema and Kam W. Leong
Mol Ther 13: S135-S136; doi:10.1016/j.ymthe.2006.08.414
357. Site-Specific Integration of Immortalization Genes in Human Adult Stem Cells Mediated by DirectIt|[trade]| Recombinases
Anna Tretiakova and Malla Padidam
Mol Ther 13: S136-S136; doi:10.1016/j.ymthe.2006.08.415
358. Lentiviral Vector Integration in Mouse Bone Marrow Stem Cells Undergoing Gene Therapy
Xiaolin Wu, Weijing He, Shawn M. Burgess, Robert A. Clark and Senlin Li
Mol Ther 13: S136-S136; doi:10.1016/j.ymthe.2006.08.416
359. Production of Megakaryocytes and Platelets from Common Marmoset (Callithrix jacchus) ES Cells by Constitutive Expression of tal1/scl Gene
Tomoko Yokoo, Ryo Kurita, Erika Sasaki, Kashiya Takasugi, Hideyuki Imoto, Yoshikuni Tanioka, Yasushi Soda and Kenzaburo Tani
Mol Ther 13: S137-S137; doi:10.1016/j.ymthe.2006.08.417
360. Transmitochondrial Stem Cells: Toward Autologous Cybrid Stem Cell Therapy and Synergistic Transient Regenerative Gene Therapy for Mitochondrial (mt)DNA Diseases
Roger Bertolotti
Mol Ther 13: S137-S137; doi:10.1016/j.ymthe.2006.08.418
361. Lentiviral Vector Transduction Efficiency and Biosafety Profile of Adult Mesenchymal Stem Cells
Barry M. McGrath, Ciara O'Shea, Linda Howard, Mary Murphy, Frank Barry, Timothy O'Brien and Padraig M. Strappe
Mol Ther 13: S137-S138; doi:10.1016/j.ymthe.2006.08.419
Abstracts
362. Evaluation the Effects of MIP-1a on Ex Vivo Expansion of Cord Blood Hematopoietic Progenitor Cells in Different Culture Media
Kamran Alimoghaddam, Mitra Khalili, Massoud Soleimani, Moezi Lili, Panthea Ghodsi, Alireza Arjmand and Ardeshir Ghavamzadeh
Mol Ther 13: S138-S138; doi:10.1016/j.ymthe.2006.08.420
363. Homing of Bone Marrow Cells to the Respiratory Epithelium in a Murine Acute Infection Model
Joanna Rejman and Massimo Conese
Mol Ther 13: S138-S138; doi:10.1016/j.ymthe.2006.08.421
364. The Effect of Overexpression of Vascular Endothelial Growth Factor in Mouse Embryonic Stem Cells on Angiogenesis
Ying Ka Lau and Jennifer L. West
Mol Ther 13: S138-S139; doi:10.1016/j.ymthe.2006.08.422
365. Human Embryonic Stem Cells: Genetic Conversion to the Fanconi Anemia Phenotype
Beiqing Pan and Christopher E. Walsh
Mol Ther 13: S139-S139; doi:10.1016/j.ymthe.2006.08.423
366. Suicide Gene Therapy of Glioma Using Genetically Engineered Human Mesenchymal Stem Cells
Hiroki Namba, Shaoyi Li, Tsutomu Tokuyama, Junkoh Yamamoto and Naoki Yokota
Mol Ther 13: S139-S139; doi:10.1016/j.ymthe.2006.08.424
367. Lentivirus Pseudotyped with Envelope Proteins F and HN from Sendai Virus Transduce Airway Epithelium Efficiency and Persistently
Uta Griesenbach, Katsuyuki Mitomo, Makoto Inoue, Lucinda Somerton, Raymond Farley, Charanjit Singh, Toshiaki Tabata, Yasuji Ueda, Satoshi Fujikawa, Kentaro Washizawa, Mamoru Hasegawa and Eric W.F.W. Alton
Mol Ther 13: S139-S140; doi:10.1016/j.ymthe.2006.08.426
368. Lentiviral Vector Strain of Origin and Target Cell Species-Specific Restriction Factors Influence Transduction Efficiency
Christoph A. Kahl, Paula M. Cannon, Jill Oldenburg and Donald B. Kohn
Mol Ther 13: S140-S140; doi:10.1016/j.ymthe.2006.08.427
369. Development of an Amplifiable Gene Expression System in Lentivirus Vectors
Kit L. Shaw, Karen Pepper, Denise Petersen, Shundi Ge, Gay Crooks and Donald B. Kohn
Mol Ther 13: S140-S140; doi:10.1016/j.ymthe.2006.08.428
370. CRM1 Enhances the Lentiviral Vector Production
Hsin-Lung Lo, Tammy Chang, Paola M. Marcovecchio, Priscilla Yam, John A. Zaia and Jiing-Kuan Yee
Mol Ther 13: S141-S141; doi:10.1016/j.ymthe.2006.08.429
371. Optimization of Feline Immunodeficiency Viral Vectors for RNA Interference
Scott Q. Harper, Patrick D. Staber, Christine Rowley, Sarah Fineberg, Dalyz Ochoa, Colleen Stein and Beverly L. Davidson
Mol Ther 13: S141-S141; doi:10.1016/j.ymthe.2006.08.430
372. Optimizing Foamy Virus Vectors That Inhibit HIV Infection
Jason A. Taylor, Lucia Vojtech, Erik M. Olson, James M. Allen, Grant D. Trobridge, David W. Russell and Robert E. Richard
Mol Ther 13: S141-S142; doi:10.1016/j.ymthe.2006.08.431
373. Targeting the Central Nervous System by Intravenous Administration of a Targeting Lentiviral Vector
Koki Morizono, Yiming Xie, Gene-Errol Ringpis, Nonia Pariente and Irvin S.Y. Chen
Mol Ther 13: S142-S142; doi:10.1016/j.ymthe.2006.08.432
374. Hepatitis Delta Virus-Mediated Amplification of Therapeutic RNAi
Dirk Haussecker, Menashe Elazar, Jeff S. Glenn and Mark A. Kay
Mol Ther 13: S142-S142; doi:10.1016/j.ymthe.2006.08.433
375. A Glaucoma Gene Therapy Model: Eighteen Cat Study Revealing Long-Term Targeted Genetic Modification of the Anterior Chamber by Lentiviral Vectors
Pranay D. Khare, Nils Loewen, Roman Barraza, Michael Fautsch, Douglas Johnson and Eric Poeschla
Mol Ther 13: S142-S143; doi:10.1016/j.ymthe.2006.08.434
376. Hepatic Tropism of Adenoviral Type 5 Vectors Can Be Mediated by Multiple Coagulation Factors
Alan L. Parker, Campbell G. Nicol, Simon N. Waddington, Suzanne M. Buckley, Dmitry M. Shayakhmetov, Shaoheng H. Ni, Andre Lieber, John H. McVey, Laura Denby, Stuart A. Nicklin and Andrew H. Baker
Mol Ther 13: S143-S143; doi:10.1016/j.ymthe.2006.08.436
377. Intravascular Delivery of Adenovirus Vectors Rapidly Targets Platelets to the Reticuloendothelial System
Daniel Stone, Shaoheng Ni, Zong-Yi Li, Dmitry Shayakhmetov and Andre Lieber
Mol Ther 13: S143-S144; doi:10.1016/j.ymthe.2006.08.437
378. Phase I Trial of Intravenous Infusion of Onyx 015 and Enbrel in Solid Tumor Patients
Gerald Edelman, Neil Senzer, Michael Nemunaitis, Casey Cunningham, Paige Sovern, Alex Tong and John Nemunaitis
Mol Ther 13: S144-S144; doi:10.1016/j.ymthe.2006.08.438
379. Identification of Structural Aspects of Adenovirus Interactions with Host Factors In Vivo Using Tandem Mass Spectrometry
Oleksandr Kalyuzhniy, Catalin Doneanu, Martin Sadilek and Dmitry M. Shayakhmetov
Mol Ther 13: S144-S144; doi:10.1016/j.ymthe.2006.08.439
380. Alternative Cellular Receptor for B-Group Adenoviruses: Implications for Gene Therapy
Sebastian Tuve, Hongjie Wang, Anuj Gaggar, Ying Liu and Andre Lieber
Mol Ther 13: S145-S145; doi:10.1016/j.ymthe.2006.08.440
381. The Adenoviral Fiber Shaft Is a Major Determinant of Kupffer Cell Necrosis
Jeffrey S. Smith, Jie Tian, Susan C. Stevenson and Andrew P. Byrnes
Mol Ther 13: S145-S145; doi:10.1016/j.ymthe.2006.08.441
382. The Polysaccharide Mannan as a Novel Chemical Coupling Partner for Adenovirus Vectors with a Potential Use for Genetic Vaccination
Sigrid Espenlaub, Andreas Wortmann, Tatjana Dick, Stefan Kochanek and Florian Kreppel
Mol Ther 13: S145-S146; doi:10.1016/j.ymthe.2006.08.442
383. Polyethylene Glycol Modification of Adenovirus Vectors Reduces Thrombocytopenia through Decreased Platelet Clearance and Activation
Hoyin Mok, Francisca C. Gushkin, Sean Hofherr, Jose A. Lopez and Michael A. Barry
Mol Ther 13: S146-S146; doi:10.1016/j.ymthe.2006.08.443
384. Species B Adenovirus and Hematopoietic Cells Revisited
Goeran Wadell, Anna Segerman, William Burmeister, Steven Cusack, Emma Andersson, Karin Edlund, Praveen Papareddy, Dan Gustafsson, Kristina Lindman, Marko Marttila, Johan Skog, Niklas Arnberg and Ya-fang Mei
Mol Ther 13: S146-S146; doi:10.1016/j.ymthe.2006.08.444
385. Tol2 Transposon as a Gene Therapy Vector: Characterization, Optimization and Correction of Hereditary Tyrosinemia Type 1 in Mouse
Darius Balciunas, Andrew Wilber, Kirk Wangensteen, Jason Bell, Aron Geurts, Perry B. Hackett, David A. Largaespada, R. Scott McIvor and Stephen C. Ekker
Mol Ther 13: S147-S147; doi:10.1016/j.ymthe.2006.08.446
386. Chromosomal Integration Sites of Double-Stranded Linear DNA in Mouse ES Cells
Fumi Ohbayashi and Ko Mitani
Mol Ther 13: S147-S147; doi:10.1016/j.ymthe.2006.08.447
387. Advantageous Properties of the piggyBac Transposon System for Gene Transfer in Human Cells
Matthew H. Wilson, Craig J. Coates, Edward J. Rebar and Alfred L. George Jr.
Mol Ther 13: S147-S148; doi:10.1016/j.ymthe.2006.08.448
388. Chromosomal Rearrangements in Mammalian Cells Are Induced at High Frequency by the Bacteriophage Derived Integrase phiC31
Anja Ehrhardt, Jeffrey A. Engler, Hui Xu, Athena Cherry and Mark A. Kay
Mol Ther 13: S148-S148; doi:10.1016/j.ymthe.2006.08.449
389. Directed Transposon Integration in Human Cells
Stephen R. Yant, Yong Huang, Bassel Akache and Mark A. Kay
Mol Ther 13: S148-S149; doi:10.1016/j.ymthe.2006.08.450
390. Phage c31 Integrase Induces Chromosomal Aberrations in Primary Human Fibroblasts
Jian Liu, Iben Jeppesen, Kate Nielsen and Thomas G. Jensen
Mol Ther 13: S149-S149; doi:10.1016/j.ymthe.2006.08.451
391. De Novo Human Artificial Chromosome Formation Is Predetermined by Initial Chromatin Assembly and Transcriptional Patterns after Transfection
Hiroshi Nakashima, Megumi Nakano, Ryoko Ohnishi, Yasushi Hiraoka, Yasufumi Kaneda, Akio Sugino and Hiroshi Masumoto
Mol Ther 13: S149-S149; doi:10.1016/j.ymthe.2006.08.452
392. Duration of Expression of the Sleeping Beauty Transposase Gene in Mouse Liver Following Hydrodynamic Delivery
Jason B. Bell, Elena L. Aronovich, Brenda L. Koniar, Jeffrey M. Schreifels, Ann M. Clifford, Nathan D. Hoekstra and Perry B. Hackett
Mol Ther 13: S150-S150; doi:10.1016/j.ymthe.2006.08.453
393. Non-Viral Gene Transfer Using the Sleeping Beauty Transposon for Long-Term Gene Expression in the CNS of Neonatal Mice
Zachary L. Demorest, Walter C. Low, Andrew B. Freese and John R. Ohlfest
Mol Ther 13: S150-S150; doi:10.1016/j.ymthe.2006.08.454
394. Neuron-Specific, In Vivo Gene Delivery Mediated by Non-Viral Vectors
In-Kyu Park, Jurate Lasiene, Jennifer M. Knox, Shinn-Huey Chou, Philip J. Horner and Suzie H. Pun
Mol Ther 13: S151-S151; doi:10.1016/j.ymthe.2006.08.456
395. Role of Caveoli on Membrane Raft in the Internalization of Non-Viral Vectors
Peng H. Tan, Maria Manunta and Andrew J.T. George
Mol Ther 13: S151-S151; doi:10.1016/j.ymthe.2006.08.457
396. Quantitative Analysis of Non-Viral Gene Therapy in a Three-Dimensional Liver Bioreactor
Nathan Tedford, Jennifer Fang, Karel Domansky, Linda G. Griffith and Douglas A. Lauffenburger
Mol Ther 13: S151-S152; doi:10.1016/j.ymthe.2006.08.458
397. Compacted DNA Nanoparticles Transfect Cells by Binding to Cell Surface Nucleolin
Xuguang Chen and Pamela B. Davis
Mol Ther 13: S152-S152; doi:10.1016/j.ymthe.2006.08.459
398. Extracellular Matrix Identity and Surface Density Alter Transfection by Complexes Delivered from a Cell-Adhesive Substrate
Zain Bengali and Lonnie D. Shea
Mol Ther 13: S152-S153; doi:10.1016/j.ymthe.2006.08.460
399. Solid Nanobeads Prevents Polycations from Entering the Nuclei and Enhanced Transfection Efficiency
Wenzhong Li, Nan Ma, Leelee Ong, Alexander Kaminski, Peter Lorenz, Brigitte M. P|[uuml]|tzer, Ren-Ke Li, Christof Stamm and Gustav Steinhoff
Mol Ther 13: S153-S153; doi:10.1016/j.ymthe.2006.08.461
400. Peptide-Mediated Gene Transfer of Lipid/ DNA-Based Complexes to Cells Expressing CXC- Receptor 4
Wouter H. Driessen, Nobutaka Fujii, Hirokazu Tamamura and Sean M. Sullivan
Mol Ther 13: S153-S153; doi:10.1016/j.ymthe.2006.08.462
401. Quantitative Bioluminescence Imaging of Transgene Expression In Vivo
Garrett R. Rettig, Marie McAnuff, Dijie Liu, Ji-Seon Kim and Kevin G. Rice
Mol Ther 13: S154-S154; doi:10.1016/j.ymthe.2006.08.463
402. Intracellular Trafficking of QD-FRET Nanoparticles for Gene Delivery
Hunter H. Chen, Yi-Ping Ho, Tza-Huei Wang and Kam W. Leong
Mol Ther 13: S154-S154; doi:10.1016/j.ymthe.2006.08.464
403. Long-Term, High alpha-L-iduronidase Expression in MPS I Dogs Following Neonatal, Intravenous, Retroviral Vector Gene Therapy
Anne Traas, Ping Wang, Xiucui Ma, Patricia O'Donnell, Meg Sleeper, Gus Aguirre, Mark Haskins and Katherine P. Ponder
Mol Ther 13: S154-S155; doi:10.1016/j.ymthe.2006.08.466
404. Therapeutic Correction of PKU in a Mouse Model by Ectopic Expression of PAH and Its BH4- Cofactor Genes in Skeletal Muscle by a Recombinant Triple-Cistronic AAV2-Based Pseudotype 1 Vector
Zhaobing Ding, Cary O. Harding, Alexandre Rebuffat, Lina Elzaouk, Jon A. Wolff and Beat Thony
Mol Ther 13: S155-S155; doi:10.1016/j.ymthe.2006.08.467
405. Correction of the Murine Model of Hereditary Tyrosinemia Type I Using Messenger RNA as a Source of Transposase for Sleeping Beauty Mediated Integration of the FAH Gene
Andrew Wilber, Kirk J. Wangensteen, Yixin Chen, Lijuan Zhou, Joel L. Frandsen, Jason Bell, Zongyu Chen, Stephen C. Ekker, R. Scott McIvor and Xin Wang
Mol Ther 13: S155-S156; doi:10.1016/j.ymthe.2006.08.468
406. rAAV-Mediated Expression of Wnt10b cDNA Prevents the Development of Obesity in DIO Rats
George Aslanidi, Glenn Philipsberg, Vadim Kroutov, Kenneth Lamb, Erik Kohlbrenner, Martha Campbell-Thompson, Glenn Walter, Philip J. Scarpace and Sergei Zolotukhin
Mol Ther 13: S156-S156; doi:10.1016/j.ymthe.2006.08.469
407. A Single Unilateral Injection of AAV1-ASA and AAV1-FGE Vectors into the Hippocampus Results in Bilateral Expression and Widespread Distribution of ASA and Prevention of Sulfatide Storage in the Whole Brain of MLD Model Mice
Toshiyuki Kurai, Sanae Hisayasu, Yukihiko Hirai, Makoto Migita, Hidenori Suzuki and Takashi Shimada
Mol Ther 13: S156-S156; doi:10.1016/j.ymthe.2006.08.470
408. Safety of Lysosomal Enzymes Over-Expression in HSC for Gene Therapy of Storage Disorders
Alessandra Biffi, Ilaria Visigalli, Martina Cesani, Alessia Capotondo, Francesca R. Santoni de Sio, Isabella Pallavicini, Anna Zingale and Luigi Naldini
Mol Ther 13: S157-S157; doi:10.1016/j.ymthe.2006.08.471
409. Complete Correction of Enzymatic Deficiency and Lysosomal Storage throughout the Brain in a Mouse Model of GM1-gangliosidosis after Neonatal Intracerebroventricular Injection of an AAV1 Vector Encoding Lysosomal Acid Beta- galactosidase
Marike L. D. Broekman, Rena Baek, Laryssa A. Comer, Thomas N. Seyfried and Miguel Sena-Esteves
Mol Ther 13: S157-S157; doi:10.1016/j.ymthe.2006.08.472
410. Physiological Correction of Glycogen Storage Disease Type II Using Adeno-Associated Virus Serotype 1 Vectors
Cathryn Mah, Christina A. Pacak, Kerry O. Cresawn, Lara R. DeRuisseau, Sean Germain, Melissa A. Lewis, David D. Fuller and Barry J. Byrne
Mol Ther 13: S158-S158; doi:10.1016/j.ymthe.2006.08.473
411. The Metabolic Basis of Sexual Dimorphism in PKU Mice after PAH Gene Treatment
Li Chen and Savio L.C. Woo
Mol Ther 13: S158-S158; doi:10.1016/j.ymthe.2006.08.474
412. A Novel Friedreich's Ataxia Model and In Vivo Gene Rescue Using HSV-1 Amplicon Vectors in Transgenic Mice
Filip Lim, Gloria Palomo, Christina Mauritz, Alfredo Gimenez, Belen Illana, Francisco Wandosell and Javier Diaz-Nido
Mol Ther 13: S158-S158; doi:10.1016/j.ymthe.2006.08.476
413. Targeting the Low-Density Lipoprotein Receptor on the Blood-Brain Barrier for Transport of |[beta]|-Glucoronidase Can Treat the Neurological Degeneration of MPSVII
Brian J. Spencer and Inder M. Verma
Mol Ther 13: S159-S159; doi:10.1016/j.ymthe.2006.08.477
414. Non-Allele Specific RNA Interference in the CAG140 Knock-In Mouse Model of Huntington's Disease
Jodi L. McBride, Scott Q. Harper, Patrick D. Staber, Ines H. Martins, Haim Burstein, Richard W. Peluso, Barry Polisky, Barrie J. Carter and Beverly L. Davidson
Mol Ther 13: S159-S159; doi:10.1016/j.ymthe.2006.08.478
415. Stimulating Full-Length SMN2 Expression by Delivering Bi-Functional RNAs Via a Viral Vector
Travis D. Baughan, Monir Shababi, Gregory E. Tullis and Christian L. Lorson
Mol Ther 13: S159-S160; doi:10.1016/j.ymthe.2006.08.479
416. Gene Therapy for Parkinsons Disease by In Vivo Plasmid Transfer of Human Hepatocyte Growth Factor in Primate Model
Akihiko Ishida, Hiromi Koike and Ryuichi Morishita
Mol Ther 13: S160-S160; doi:10.1016/j.ymthe.2006.08.480
417. Combination Brain and Systemic Injections of AAV Results in Whole Body Therapy and Extension of Lifespan in the Niemann-Pick Mouse
Marco A. Passini, Jie Bu, Jonathan A. Fidler, Joseph W. Foley, James C. Dodge, Robin J. Ziegler, Wendy W. Yang, Jennifer Clarke, Tatyana V. Taksir, Denise A. Griffiths, Michael A. Zhao, Catherine R. O'Riordan, Lamya S. Shihabuddin, Edward H. Schuchman and Seng H. Cheng
Mol Ther 13: S160-S160; doi:10.1016/j.ymthe.2006.08.481
418. AAV-Mediated sFLT-1 Gene Therapy for Ocular Neovascularization: Longevity, Toxicity and Efficacy Results from Mice and Monkeys
E.P. Rakoczy, C.M. Lai, W.Y. Shen, M. Brankov, N. Barnett, S.Y. Lee, S.G. Leaver, I. Yeo, C.L. Ang and I.J. Constable
Mol Ther 13: S160-S161; doi:10.1016/j.ymthe.2006.08.482
419. Rescue of Cone Photoreceptors after Lentiviral Gene Transfer of Rpe65 cDNA in Knockout Mouse Models of Leber Congenital Amaurosis
Alexis-Pierre Bemelmans, Corinne Kostic, Dana Hornfeld, Meriem Tekaya, Sylvain V. Crippa, William W. Hauswirth, Janis Lem, Mathias Seeliger, Andreas Wenzel and Yvan Arsenijevic
Mol Ther 13: S161-S161; doi:10.1016/j.ymthe.2006.08.483
420. Hydrodynamic Limb Vein Delivery of Naked IGF-1 Plasmid DNA Provides Therapeutic Benefit in SOD1(G93A) Murine ALS Model
Gyula Acsadi, Roumen Anguelov, Xingli Li, Mary Kay Bates, Jon A. Wolff and Hans Herweijer
Mol Ther 13: S161-S161; doi:10.1016/j.ymthe.2006.08.484
421. Killing of Normal Cells Combined with TLR Engagement and CD40 Ligation Generates Autoimmune T Cell Reactivity Sufficient To Treat Large Established Tumors
Luis Sanchez-Perez, Gregory Daniels, Timothy Kottke, Rosa Maria Diaz, Jill Thompson, Heung Chong, Alan Melcher and Richard Vile
Mol Ther 13: S162-S162; doi:10.1016/j.ymthe.2006.08.486
422. Enhancement of Human Monocyte-Derived Dendritic Cell Functions by Adenovirus- Mediated RNA Interference of STAT-3
Tomoko Iwata, Hidetoshi Sumimoto, Hiroyuki Mizuguchi and Yutaka Kawakami
Mol Ther 13: S162-S162; doi:10.1016/j.ymthe.2006.08.487
423. Combination of Sleeping Beauty-Mediated INF-gamma Gene Transfer with CpG Oligodeoxynucleotides Provides Long-Term Survival of Intracranial Glioblastoma in Mice
Anhua Wu, Zachary L. Demorest, Isabelita Vengco, Wei Chen, Walter C. Low, Andrew B. Freese and John R. Ohlfest
Mol Ther 13: S162-S163; doi:10.1016/j.ymthe.2006.08.488
424. Myd88/TLR Signaling Is Required for Immunotherapy-Mediated Glioblastoma Regression
James F. Curtin, Gwendalyn D. King, Marianela Candolfi, Chunyan Liu, Kathrin S. Michelsen, Moshe Arditi, Tamer M. Fakhouri, Begonya Comin-Anduix, Antoni Ribas, Pedro R. Lowenstein and Maria G. Castro
Mol Ther 13: S163-S163; doi:10.1016/j.ymthe.2006.08.489
425. Translation of Enhanced Dendritic Cell Vaccines Using a CID-Inducible CD40 Receptor
Natalia Lapteva, Brent A. Hanks, Jianghong Jiang, Kevin M. Slawin and David M. Spencer
Mol Ther 13: S163-S164; doi:10.1016/j.ymthe.2006.08.490
426. dSLIM Immunomodulators Induce Anti- Tumor Responses Both In Vitro and In Vivo
Manuel Schmidt, Javier Cristobal, Astrid Sander, Bernadette Brzezicha, Sven A. Konig Merediz and Burghardt Wittig
Mol Ther 13: S164-S164; doi:10.1016/j.ymthe.2006.08.491
427. Adenovirus Mediated GRP94/gp96 Expression in Treatment of Neuroblastoma
Shanling Liu, Jiangao Zhu, He Wang, Takashi Kon and Chuan- Yuan Li
Mol Ther 13: S164-S164; doi:10.1016/j.ymthe.2006.08.492
428. Development of an Effective Safety Switch for Selective Elimination of Human T Cells In Vivo after Adoptive Transfer
Tom van Meerten, Henk Rozemuller, Wendy Mackus, Paul Parren, Jan van de Winkel, Marie-Jose Claessen, Rozemarijn van Rijn, Anton Hagenbeek, Anton Martens and Saskia Ebeling
Mol Ther 13: S164-S165; doi:10.1016/j.ymthe.2006.08.493
429. Adenoviral-Mediated Interleukin-15 Receptor-|[alpha]| Gene Therapy of Murine Breast Cancer
Brian J. Morrison, Yutaka Tagaya, Jason C. Steel, Poonam Mannan, Thomas A. Waldmann, John C. Morris and Yoshio Sakai
Mol Ther 13: S165-S165; doi:10.1016/j.ymthe.2006.08.494
430. EGFRvIII Retargeted Oncolytic Measles Virus Strains Have Significant Antitumor Activity Against Gliomas
Cory Allen, Sompong Vongpunsawad, Takafumi Nakamura, C. David James, Mark Schroeder, Roberto Cattaneo, Caterina Giannini, James Krempski, Stephen J. Russell and Evanthia Galanis
Mol Ther 13: S165-S166; doi:10.1016/j.ymthe.2006.08.496
431. Treatment of Multi-Focal CRC Liver Metastases with Repeated Infusion of Oncolytic Vesicular Stomatitis Virus Via the Hepatic Artery
Minoru Yamaki, Katsunori Shinozaki, Savio L.C. Woo and Toshimasa Asahara
Mol Ther 13: S166-S166; doi:10.1016/j.ymthe.2006.08.497
432. Characterization of a Novel Oncolytic Measles Virus Retargeted Against the Urokinase Receptor: In Vitro and In Vivo Studies
Jaime R. Merchan, Caili Tong, Takafumi Nakamura, Ianko Iankov and Stephen J. Russell
Mol Ther 13: S166-S167; doi:10.1016/j.ymthe.2006.08.498
433. Combination Therapy of Androgen-Independent Prostate Cancer Using a Prostate Restricted Replicative Adenovirus and a Replication-Defective Adenovirus Encoding Human Endostatin-Angiostatin Fusion Gene
Xiong Li, Sudhanshu P. Raikwar, You-Hong Liu, Sang-Jin Lee, Yan-Ping Zhang, Shaobo Zhang, Liang Cheng, Sang-Don Lee, Beth Elisa Juliar, Thomas A. Gardner, Meei-Huey Jeng and Chinghai Kao
Mol Ther 13: S167-S167; doi:10.1016/j.ymthe.2006.08.499
434. Oncolytic Virotherapy Using the HSV Mutant rQNestin34.5 towards CD133+ Brain Tumor Stem Cells
Akihiro Otsuki, Ankita Patel, Suzanne Camilli, Kazue Kasai, Sigeru Tanaka, E. Antonio Chiocca and Yoshinaga Saeki
Mol Ther 13: S167-S167; doi:10.1016/j.ymthe.2006.08.500
435. A Fiber-Modified, Relaxin-Expressing Oncolytic Adenovirus Prolongs Survival of Tumor Bearing Mice
Shanthi Ganesh, Melinda VanRoey, Neeraja Idamakanti and Karin Jooss
Mol Ther 13: S167-S168; doi:10.1016/j.ymthe.2006.08.501
436. Coxsackievirus A21 Has Potent Oncolytic Activity in Multiple Myeloma
Elizabeth M. Hadac and Stephen J. Russell
Mol Ther 13: S168-S168; doi:10.1016/j.ymthe.2006.08.502
437. An E1b-19kD-Deleted p53-Expressing Replicating Adenovirus Markedly Enhances the Induction of Apoptosis When Combined with Cisplatin in Head and Neck Cancer Cells
David I. Kutler, Harald Sauthoff, Jin Cheng, Yao Qi Huang, Sheila Heitner, William N. Rom and John G. Hay
Mol Ther 13: S168-S168; doi:10.1016/j.ymthe.2006.08.503
438. Targeting HSV-1 Virions for Specific Binding to Epidermal Growth Factor Receptor-VIII on Tumor Cells
Paola Grandi, Juliet Fernandez, Oscar Szentirmai, Robert Carter, Xandra O. Breakefield and Miguel Sena-Esteves
Mol Ther 13: S168-S168; doi:10.1016/j.ymthe.2006.08.504
439. Genetic Manipulation of Liver Sinusoidal Endothelial Cells (LSEC) and Repopulation of the Mouse Liver with Transplanted LSEC Has Therapeutic Implications
Antonia Follenzi, Daniel Benten, Marco Ulla, Michele De Palma, Phyllis Novikoff and Sanjeev Gupta
Mol Ther 13: S169-S169; doi:10.1016/j.ymthe.2006.08.506
440. Overexpression of Bcl-2 Prevented MSCs from Apoptosis and Improved Heart Function
Nan Ma, Wenzhong Li, Catharina Nesselmann, Leelee Ong, Alexander Kaminski, Brigitte M. P|[uuml]|tzer, Ren-Ke Li, Christof Stamm and Gustav Steinhoff
Mol Ther 13: S169-S169; doi:10.1016/j.ymthe.2006.08.507
441. Stable Oligo-to Polyclonal Hematopoiesis without Clonal Exhaustion Following Extended Reduced Intensity Selection of MGMT-P140K Expressing Murine Repopulating Stem Cells in Serially Transplanted Mice
C.R. Ball, I.H. Pilz, M. Schmidt, M. Schrempp, C. von Kalle and H. Glimm
Mol Ther 13: S169-S170; doi:10.1016/j.ymthe.2006.08.508
442. LV Expressing MR Reporter Genes Allows In Vivo Monitoring of Stem Cell Gene Therapy
Mario Amendola, Letterio S. Politi, Marcello Cadioli, Rossella Galli, Elena Binda, Andrea Falini, Sonia Levi, Giuseppe Scotti, Alessandra Biffi and Luigi Naldini
Mol Ther 13: S170-S170; doi:10.1016/j.ymthe.2006.08.509
443. Successful Long-Term Doxycycline-Regulated Transgene Expression in the Retina of Nonhuman Primates Following Subretinal Injection of Recombinant AAV Vectors
Knut Stieger, Guyl|[egrave]|ne Le Meur, Francoise Lasne, Michel Weber, Jack-Yves Deschamps, Delphine Nivard, Alexandra Mendes-Madeira, Nathalie Provost, Laurent Martin, Philippe Moullier and Fabienne Rolling
Mol Ther 13: S170-S170; doi:10.1016/j.ymthe.2006.08.510
444. Use of dsAAV8-Mediated Gene Transfer to Endogenous |[beta]|-Cells To Investigate the Therapeutic Efficacy of Immunoregulatory Gene Products in Preventing the Onset of Diabetes in NOD Mice
Khaja K. Rehman, Zhong Wang, Xiao Xiao and Paul D. Robbins
Mol Ther 13: S171-S171; doi:10.1016/j.ymthe.2006.08.511
445. Developmental Stage Determines Distribution of Organ Transduction after Intra-Amniotic Injection of Lentiviral Vector
Masayuki Endo, Tiago H. Coelho, Phil W. Zoltick and Alan W. Flake
Mol Ther 13: S171-S171; doi:10.1016/j.ymthe.2006.08.512
446. Inhibition of Hepatic Stellate Cell Activation and Liver Fibrosis by Expression of Cytoglobin In Vivo
Ruian Xu, Phillip Harrison, Xinyan Li, Miao Chen, Hua Li, Pik-to Cheung, Weidong Xiao and Farzin Farzaneh
Mol Ther 13: S171-S172; doi:10.1016/j.ymthe.2006.08.513
447. AP20187-Inducible Insulin-Like Effects in Diabetic Muscle and Liver Transduced with AAV
Gabriella Cotugno, Pietro Formisano, Ferdinando Giacco, Victor M. Rivera, Francesco Beguinot and Alberto Auricchio
Mol Ther 13: S172-S172; doi:10.1016/j.ymthe.2006.08.514
448. Suicide Gene-Mediated Conditional Ablation of Tumors Derived from Transplanted Embryonic Stem Cells
Juyeon Jung, Joanne Kim, Robert G. Pergolizzi and Ronald G. Crystal
Mol Ther 13: S172-S172; doi:10.1016/j.ymthe.2006.08.516
449. Sca-1+ Cell-Based Gene Therapy with a Modified Fibroblast Growth Factor 2 (FGF2) Increased Endosteal/Trabecular Bone Formation in Mice
Susan L. Hall, K.-H. William Lau, Shin-Tai Chen, Matilda H.-C. Sheng, Apurva K. Srivastava, Henry J. Klamut, Jon E. Wergedal, Daila S. Gridley, Subburaman Mohan and David J. Baylink
Mol Ther 13: S173-S173; doi:10.1016/j.ymthe.2006.08.517
450. Novel, Injectable, Genetically Engineered Stem Cell-Based System for Anterior Spinal Fusion
Rod J. Oskouian, Gadi Pelled, Yoram Zilberman, Yamit Tal, Zulma Gazit and Dan Gazit
Mol Ther 13: S173-S174; doi:10.1016/j.ymthe.2006.08.518
451. AAV-BDNF Augments Neurogenesis in Both the Normal Adult Rat Brain and the Quinolinic Acid Lesion Model of Huntington's Disease
Rebecca A. Henry, Stephanie M. Hughes, Richard L.M. Faull and Bronwen J. Connor
Mol Ther 13: S174-S174; doi:10.1016/j.ymthe.2006.08.519
452. Bone Marrow Stem Cells Are Potent Targets for Gene Therapy of Epidermolysis Bullosa, a Genetic Blistering Skin Disease
Katsuto Tamai, TaKehiko Yamazaki, Otsuru Satoru, Takenao Chino, Yasushi Kikuchi and Yasufumi Kaneda
Mol Ther 13: S174-S174; doi:10.1016/j.ymthe.2006.08.520
453. Injectionof Different Adult Cell Types into Mouse Myocardium Three Days after Myocardial Infarction Using a Novel Echo-Guided Technique Improves Cardiac Function
Yan Zhang, Junya Takagawa, Richard E. Sievers, Maelene L. Wong, Christian Heiss, Mohan N. Viswanathan, Neel K. Kapasi, Jianqin Ye, Elyse Foster, William Grossman, Matthew L. Springer and Yerem Yeghiazarians
Mol Ther 13: S175-S175; doi:10.1016/j.ymthe.2006.08.521
454. Recognition of Tumor Antigens by In Vitro Developed T Cells from Hematopoietic Stem Cells Retrovirally Transduced with TCR Genes
Yangbing Zhao, Zhili Zheng, Cyrille J. Cohen, Steven A. Rosenberg and Richard A. Morgan
Mol Ther 13: S175-S175; doi:10.1016/j.ymthe.2006.08.522
455. Genetically Engineered Adult Stem Cells and Hybrid Scaffolds as a Platform for Intervertebral Disc Regeneration
Nadav Kimelman, Rod J. Oskouian, Yoram Zilberman, Gadi Pelled, Zulma Gazit and Dan Gazit
Mol Ther 13: S175-S176; doi:10.1016/j.ymthe.2006.08.523
456. Gene Transfer to Skin Stem Cells by Early Gestational Intra-Amniotic Injection of Lentiviral Vector
Masayuki Endo, Phil W. Zoltick, William H. Peranteau, Mayumi Ito, George Cotsarelis and Alan W. Flake
Mol Ther 13: S176-S176; doi:10.1016/j.ymthe.2006.08.524
457. Reverse Transcriptase Deficient Retroviral Vectors for Transient Cell Modification
Melanie Galla, Axel Schambach, Elke Will and Christopher Baum
Mol Ther 13: S177-S177; doi:10.1016/j.ymthe.2006.08.526
458. Development of Non-Integrating and Site- Specifically Integrating Lentiviral Vectors
Luis Apolonia, Simon Waddington, Mary Collins, Adrian Thrasher and Nicola Philpott
Mol Ther 13: S177-S177; doi:10.1016/j.ymthe.2006.08.527
459. Murine Study To Evaluate Long-Term Transgene Expression of the MSCV-MGMTP140K wc Retroviral Vector in Support of a Phase I Gene Transfer Trial-Limitations of the Murine Model as a Pre-Clinical Tool
Elke Will, Jeff Bailey, Todd Schuesler, Brenden Balcik, Ben Burzynski, David Witte, Gerlinde Layh-Schmitt, Christof vonKalle, Christopher Baum, Brian P. Sorrentino, Lars M. Wagner, Lilith Reeves and David A. Williams
Mol Ther 13: S177-S178; doi:10.1016/j.ymthe.2006.08.528
Abstracts
460. MGMTP140K Vector Constructs for Efficient In Vivo Enrichment of Genetically Corrected Cells Following Hematopoietic Cell Gene Transfer
U.R. Sorg, V. Kleff, G. Nagel, B. Opalka, J. Thomale, B. Kaina and T. Moritz
Mol Ther 13: S178-S178; doi:10.1016/j.ymthe.2006.08.529
461. Evaluation of In Vivo Model Systems for Safety Assessment of HIV-1 Based Lentiviral Vectors
Yuan Zhao, Selina Azam, Kenneth Keating and Robin Thorpe
Mol Ther 13: S178-S178; doi:10.1016/j.ymthe.2006.08.530
462. Comparison of EMCV IRES and FMDV 2A Cleavage Factor for Expression of Canine MGMT and a Second Transgene Using HIV-1 Vectors
Srinivas N. Kumar, Tatiana Zaboikina, Michail Zaboikin and Friedrich G. Schuening
Mol Ther 13: S179-S179; doi:10.1016/j.ymthe.2006.08.531
463. COX-2-Based Gene Therapy: Reduction of Intraocular Pressure in a Glaucoma Gene Therapy Animal Model with Lentiviral Vectors Expressing COX-2, a Prostaglandin Synthase, or a Prostaglandin Receptor
Roman A. Barraza and Eric M. Poeschla
Mol Ther 13: S179-S179; doi:10.1016/j.ymthe.2006.08.532
464. Use of Equine Infectious Anaemia Virus (EIAV) To Mediate Indoleamine 2,3-dioxygenase Gene Transfer to Murine Corneal Allograft Transplantation Model Results in Prolongation of Allograft Survival In Vivo with Little Immunogenicity
Peng H. Tan, Sven C. Beutelspacher and Andrew J.T. George
Mol Ther 13: S179-S180; doi:10.1016/j.ymthe.2006.08.533
465. Pseudotyping Lentiviral Vectors with a Modified GP64 Envelope Proteins Redirects Gene Transfer In Vitro and In Vitro
David Markusic, Niek van Til, Alexander Kanitz, Johan Hiralall, Ronald Oude-Elferink and Jurgen Seppen
Mol Ther 13: S180-S180; doi:10.1016/j.ymthe.2006.08.534
466. Comprehensive Analyses of Diverse Lentiviral and Retroviral Vectors for Post-Entry Restriction by TRIM5|[alpha]| and Implications for Gene Therapy
Dyana T. Saenz and Eric M. Poeschla
Mol Ther 13: S180-S180; doi:10.1016/j.ymthe.2006.08.535
467. Lentiviral Vector (LV) Non-Coding Elements That Impart High Titers and Expression to |[beta]|-Globin (h|[beta]|) Cassettes
F. Urbinati, P. Xia, A. Perumbeti, M. Xia, A. Corsinotti, A. Zarzuela, N. Perelman and P. Malik
Mol Ther 13: S181-S181; doi:10.1016/j.ymthe.2006.08.536
468. Evaluation of Factors Influencing the Production Titers of SIV-Derived Lentiviral Vectors
Nora Naumann, Suk See De Ravin, Morvarid Moayeri, Uimook Choi, Yasuhiro Ikeda and Harry L. Malech
Mol Ther 13: S181-S181; doi:10.1016/j.ymthe.2006.08.537
469. Optimization of the Lentivirus Vector Containing the MSCV-U3 and EF1|[alpha]| Double Internal Promoters
Naoya Uchida, Hideki Hanawa, Motoko Yamamoto and Takashi Shimada
Mol Ther 13: S182-S182; doi:10.1016/j.ymthe.2006.08.538
470. ABCB4 P-Glycoprotein Reduces Infectivity of Lentiviral Particles by Increasing Their Phosphatidylcholine Content
Niek P. van Til, Kirstin Heutinck, Ronald P.J. Oude Elferink and Jurgen Seppen
Mol Ther 13: S182-S182; doi:10.1016/j.ymthe.2006.08.539
471. Chimeric Lentiviral Vectors with Safety Insurance
Kritika Kachapati, Geetanjali Sachdeva and Suresh Arya
Mol Ther 13: S182-S183; doi:10.1016/j.ymthe.2006.08.540
472. Biodistribution of Semliki Forest Virus Vectors and Effect of Preimmunizations in Mice
Juan R. Rodriguez, Erkuden Casales, Jesus Prieto and Cristian Smerdou
Mol Ther 13: S183-S183; doi:10.1016/j.ymthe.2006.08.541
473. Semliki Based Systems for the Production of Retroviral Vectors: A Safety Concern
Eric Piver, Christine Collin, No|[eacute]|mie Renault, Thierry Bru and Jean-Christophe Pages
Mol Ther 13: S183-S183; doi:10.1016/j.ymthe.2006.08.542
474. Deletion of All Membranous Genes of Recombinant Sendai Virus Results in the Dramatic Reduction of Toxicity for Pulmonary Gene Transfer in Neonatal Mice
Sakura Tanaka, Yoshikazu Yonemitsu, Mamoru Hasegawa, Tomoaki Taguchi and Katsuo Sueishi
Mol Ther 13: S184-S184; doi:10.1016/j.ymthe.2006.08.543
475. SeV-Mediated Gene Transfer after Three Re-Administrations in Mice and Sheep
Uta Griesenbach, Gerry McLachlan, Lucinda Somerton, David Collie, Makoto Inoue, Takashi Hironaka, Seng Cheng, Ronald Scheule, Toshiyuki Owaki, Alison Baker, Peter Tennant, Mamoru Hasegawa and Eric W.F.W. Alton
Mol Ther 13: S184-S184; doi:10.1016/j.ymthe.2006.08.544
476. In Vivo Repopulation of Syngenic Hematopoietic Cells Expressing GFP Transfected by Recombinant Sendai Virus |[ndash]| Toward Development of 'Cytoplasmic Gene Therapy' for Hematopoietic Disorders
Kumi Yoshida, Yoshikazu Yonemitsu, Mamoru Haswgawa and Katsuo Sueishi
Mol Ther 13: S185-S185; doi:10.1016/j.ymthe.2006.08.545
477. Replication Deficiency: The Safety Record of a New Sendai Virus Vector Generation
Sascha Bossow, Sabine Schlecht, Marian Wiegand and Wolfgang J. Neubert
Mol Ther 13: S185-S185; doi:10.1016/j.ymthe.2006.08.546
478. Novel Gene Delivery System of Sendai Virus Vector-Transduced Human Peripheral Monocytes
Tomoko Tanaka, Kashiya Takasugi, Ryo Kurita, Takafumi Nakamura, Makoto Inoue, Mamoru Hasegawa, Fumiko Ono, Keiji Terao, Yasuhiro Yoshikawa and Kenzaburo Tani
Mol Ther 13: S185-S186; doi:10.1016/j.ymthe.2006.08.547
479. Development and Characterization of a New Noncytopathic Vector Derived from Semliki Forest Virus
Erkuden Casales, Juan R. Rodriguez-Madoz, Nerea Razquin, Yolanda Cuevas, Jesus Prieto and Cristian Smerdou
Mol Ther 13: S186-S186; doi:10.1016/j.ymthe.2006.08.548
480. Gene Transfer to Gut K Cells for Physiologic Insulin Replacement in Diabetes
Eric C. Hsu, Scott Pownall, Timothy J. Kieffer, Yvonne Luu, Simon Leong, Paul D. Robbins, Xiao Xiao and Anthony T. Cheung
Mol Ther 13: S186-S186; doi:10.1016/j.ymthe.2006.08.549
481. EPIDEMIOLOGY of Seneca Valley Virus (SVV-001), a Novel Oncolytic Picornavirus for the Systemic Treatment of Patients with Solid Cancers with Neuroendocrine Features
Laura M. Hales, Brian H. Jones, Ann-Jeanette Vasko, Nick J. Knowles, Seshidar R. Police and Paul L. Hallenbeck
Mol Ther 13: S187-S187; doi:10.1016/j.ymthe.2006.08.550
482. T Cells as Carriers for Systemic Measles Virotherapy of Multiple Myeloma
Hooi T. Ong, Kosei Hasegawa, Mary Harvey, Allan Dietz, Stephen J. Russell and Kah-Whye Peng
Mol Ther 13: S187-S187; doi:10.1016/j.ymthe.2006.08.551
483. Phenotypic Correction of Von Willebrand Disease Type 3 Blood-Derived Endothelial Cells with Lentiviral Vectors Expressing Von Willebrand Factor
Simon F. DeMeyer, Karen Van hoorelbeke, Marinee K. Chuah, Inge Pareyn, Veerle Gilijns, Robert P. Hebbel, D|[eacute]|sir|[eacute]| Collen and Thierry Vandendriessche
Mol Ther 13: S187-S187; doi:10.1016/j.ymthe.2006.08.552
484. Murine Liver as a Model for AAV Replication, Recombination and Evolution
Xun Sun, You Lu, Gaung-Ping Gao, Michael T. Korn, Julio SanMiguel, Martin W. Lock and James M. Wilson
Mol Ther 13: S187-S188; doi:10.1016/j.ymthe.2006.08.554
485. Long-Term In Vivo Engraftment & Transgene Expression from CD34+ Human Hematopoietic Stem Cells Transduced with Pseudotyped rAAV
Sarah Hardy, Margaret Heerwagen, Lane Bilbrey, Kamehameha K. Wong and Saswati Chatterjee
Mol Ther 13: S188-S188; doi:10.1016/j.ymthe.2006.08.555
486. Efficient and Selective Gene Transfer Directed to Muscle by Tropism-Modified Adeno-Associated Virus Vector
Chi-Yi Yu, Bing Wang, Zhong Wang, Zhongren Cao, Juan Li and Xiao Xiao
Mol Ther 13: S188-S189; doi:10.1016/j.ymthe.2006.08.556
487. Liver-Targeted Gene Therapy in Glycogen Storage Disease Type Ia (GSD-Ia) Requires Widespread, Regulated Glucose-6-phosphatase
Dwight D. Koeberl, Lopamudra Banerjee, Andrew Bird, Baodong Sun and Y.T. Chen
Mol Ther 13: S189-S189; doi:10.1016/j.ymthe.2006.08.557
488. Adeno-Associated Viral Serotype 2/1 Is a Highly Efficient Vector for In Utero Gene Transfer to Hair Cell Precursors
Jeffrey C. Bedrosian, Michael Anne Gratton, John V. Brigande, Waixing Tang and Jean Bennett
Mol Ther 13: S189-S189; doi:10.1016/j.ymthe.2006.08.558
489. Treatment for Hemophilia B Using Self-Complimentary AAV8 Vectors
Micheal L. Hebert, Dirk Grimm, Theresa A. Storm and Mark A. Kay
Mol Ther 13: S189-S190; doi:10.1016/j.ymthe.2006.08.559
490. Successful Readministration of AAV8 Following Administration of Nondepleting CD4 Antibody at the Time of Vector Administration
Jenny H. McIntosh, Melanie Cochrane, Arnold Prizzey, Herman Waldmann, Andrew M. Davidoff and Amit C. Nathwani
Mol Ther 13: S190-S190; doi:10.1016/j.ymthe.2006.08.560
491. Mosaic AAV Vectors Display Novel Properties for Neuronal Transduction
Stanley G. LeRoy, Laryssa A. Comer, Fabricio F. Costa, Marike L.D. Broekman and Miguel Sena-Esteves
Mol Ther 13: S190-S190; doi:10.1016/j.ymthe.2006.08.561
492. Biodistribution and Integration Assessment of AAV1 gag-PR-RT(|[Delta]|RNaseH) after Intramuscular Administration in Rabbits
Bruce C. Schnepp, Michael C. Soult, Tara Allen, Pervin Anklesaria, Philip R. Johnson and Keith Munson
Mol Ther 13: S190-S191; doi:10.1016/j.ymthe.2006.08.562
493. High Efficiency Gene Targeting to Mammalian Joint Tissue Using Self- Complementary Adeno-Associated Viral Vector Serotypes
Laurie R. Goodrich, Vivian W. Choi, Beth C. DudaCarbone, C. Wayne McIlwraith and Richard J. Samulski
Mol Ther 13: S191-S191; doi:10.1016/j.ymthe.2006.08.563
494. Optimizing the Mannitol-Facilitated CNS Entry of Peripherally-Delivered AAV2 Vector
Haiyan Fu, Julianne DiRosario and Douglas M. McCarty
Mol Ther 13: S191-S191; doi:10.1016/j.ymthe.2006.08.564
495. Transfer of LEDGF to the Mouse Retina Via Systemic AAV Vector Administration
Lyudmyla G. Glushakova, Marina Gorbatuyk, Yuanging Lu, Sihong Song, Min Zheng, Toshimichi Shinohara and William W. Hauswirth
Mol Ther 13: S192-S192; doi:10.1016/j.ymthe.2006.08.565
496. AAV-Mediated, Somatic Gene Transfer to RPE Cells in Order To Study the Pathogenesis of Macular Degeneration: Proteomic and Genomic Analysis
Garrett C. Du Bois, Petya D. Radoeva and Jean Bennett
Mol Ther 13: S192-S192; doi:10.1016/j.ymthe.2006.08.566
497. Central CART Gene Delivery by Recombinant AAV Vector Decreases Lean Body Mass in Diet-Induced Obese Male Rats
Keyun Qing and Yanyun Chen
Mol Ther 13: S192-S193; doi:10.1016/j.ymthe.2006.08.567
498. AAV |[Delta]|264CFTR Enhances Maturation of |[Delta]|F508CFTR and wt CFTR Expression
Liudmila Cebotaru, Terence R. Flotte and William B. Guggino
Mol Ther 13: S193-S193; doi:10.1016/j.ymthe.2006.08.568
499. Improving the Stability of Ad-AAV Hybrid Vectors
Haim Burstein, Richard Peluso, Ziv Sandalon, Kurt Lustig and Tony Stepan
Mol Ther 13: S193-S193; doi:10.1016/j.ymthe.2006.08.569
500. Tetanus Toxin Heavy Chain-Streptoavidin Fusion Protein for Targeted Motor Neuron Gene Delivery through Metabolically Biotinylated AAV
Qingshan Teng, Jeffrey S. Bartlett, Thais Federici, Jun Yang and Nicholas M. Boulis
Mol Ther 13: S193-S193; doi:10.1016/j.ymthe.2006.08.570
501. RheoSwitch|[reg]| Therapeutic System-Inducible Recombinant AAV Vectors for Tightly Regulated Transgene Expression
Dawn Karzenowski, Zhijian J. Chen, David W. Potter and Malla Padidam
Mol Ther 13: S194-S194; doi:10.1016/j.ymthe.2006.08.571
502. Advances in the Application of Combinatorial Technology for the Optimization of Adeno-Associated Virus (AAV) Vectors
Luca Perabo, Jan Endell, Stephan Maersch, Michael Hallek and Hildegard Buening
Mol Ther 13: S194-S194; doi:10.1016/j.ymthe.2006.08.572
503. A Novel Herpes Simplex Virus Helper Based Production of Adeno-Associated Virus Vectors for Treatment of Retinal Angiogenesis
Guo-jie Ye, Chris Drogemuller, Darby Thomas, Marina Scotti, Wen Kang, David Knop, Sanford Boye, Peter Pechan, James Peterson, William Hauswirth, Abraham Scaria and Samuel Wadsworth
Mol Ther 13: S194-S194; doi:10.1016/j.ymthe.2006.08.573
504. Neuronal Affinity of a C7C Loop Peptide Identified through Phage Display
Thais Federici, James K. Liu, Qingshan Teng, Mary Garrity-Moses, Jun Yang and Nicholas M. Boulis
Mol Ther 13: S195-S195; doi:10.1016/j.ymthe.2006.08.574
505. Advances in Large-Scale Production of Recombinant Adeno-Associated Vectors
Alejandro Negrete, Masashi Urabe Urabe and Robert M. Kotin
Mol Ther 13: S195-S195; doi:10.1016/j.ymthe.2006.08.575
506. Production of Recombinant Adeno-Associated Virus Type 1 Vector Using a Herpes Simplex Virus Based System
Wen Kang, Chris Drogemuller, Marina M. Scotti and Guo-jie Ye
Mol Ther 13: S195-S195; doi:10.1016/j.ymthe.2006.08.576
507. Engineering a Novel AAV Variant for Purification Via Immobilized Metal Affinity Chromatography
James T. Koerber, Jae-Hyung Jang Jang, Julie Yu, Ravindra Kane and David V. Schaffer
Mol Ther 13: S196-S196; doi:10.1016/j.ymthe.2006.08.577
508. Development of Optimized AAV2 Vector Biosynthesis and Purification Processes To Support High Capacity Production of Clinical Vectors of High Purity and Potency
Bernd Hauck, Jitin Bajaj, Sonali Joyce, Guang Qu, Olga A. Zelenaia, Katherine A. High and J. Fraser Wright
Mol Ther 13: S196-S196; doi:10.1016/j.ymthe.2006.08.578
509. Adeno-Associated Vector Mediated Delivery of Anti-HIV Genes
Mayur C. Tamhane and Ramesh Akkina
Mol Ther 13: S196-S196; doi:10.1016/j.ymthe.2006.08.579
510. Detection and Quantification of rcAAV in rAAV Stocks by Real-Time qPCR
Traci L. Mayfield, Irina Korytov, Joyce D. Francis, David R. Knop and Richard O. Snyder
Mol Ther 13: S196-S197; doi:10.1016/j.ymthe.2006.08.580
511. An Enzyme Linked Immunosorbent Assay for the Detection of Herpes Simplex Virus Type 1 Proteins in a Novel rAAV Production and Purification Process
Guo-jie Ye and Tammy Mandell
Mol Ther 13: S197-S197; doi:10.1016/j.ymthe.2006.08.581
512. Characterization of Adsorption of Adeno-Associated Virus to Commonly Used Catheter Materials: AAV2 vs. AAV1/2
Daisy P. Cross and Marty Morris
Mol Ther 13: S197-S197; doi:10.1016/j.ymthe.2006.08.582
513. A Simple Method To Ensure Titer Conservation of AAV2 Vector Preparations Delivered with Stainless Steel Needles
Elias T. Ketchum, Kevin Kwok, Anthony Ramirez, Junshan Hao, Brian Kruegel, Dominick Vacante, Raymond Bartus and Mehdi Gasmi
Mol Ther 13: S197-S198; doi:10.1016/j.ymthe.2006.08.583
514. mRNA Transfection Results in Efficient Overexpression of Transgenes in Leukemic Cell Lines and Hematopoietic Stem Cells
Martin F. Ryser, Marcus Gentsch, Fernando Ugarte, Harry L. Malech and Sebastian Brenner
Mol Ther 13: S198-S198; doi:10.1016/j.ymthe.2006.08.585
515. Sequence Requirements for Alveolar Epithelial Cell-Specific Plasmid Nuclear Import
James V. DeGiulio and David A. Dean
Mol Ther 13: S198-S198; doi:10.1016/j.ymthe.2006.08.586
516. Development of a Minicircle Vector Free of Plasmid Bacterial DNA Sequences and Capable of |[oslash]|C31-Mediated Site-Specific Integration
Zhi-Ying Chen, Cheng-Yi He, Anja Ehrhardt, Hui Xu and Mark A. Kay
Mol Ther 13: S198-S199; doi:10.1016/j.ymthe.2006.08.587
517. Lipopolythioureas: Non Cationic System for Gene Delivery
Jeanne Leblond, Nathalie Mignet, Maria-Vittoria Spanedda, Daniel Scherman and Jean Herscovici
Mol Ther 13: S199-S199; doi:10.1016/j.ymthe.2006.08.588
518. Mechanism of Difference in the Transcription Activity of Nucleus-Delivered Transgene Introduced by Adenovirus and Lipoplex
Hidetaka Akita, Susumu Hama, Hiroyuki Mizuguchi and Hideyoshi Harashima
Mol Ther 13: S199-S199; doi:10.1016/j.ymthe.2006.08.589
519. Development of S/MAR Plasmid Vectors for Persistent Expression and Maintenance, In Vivo
Orestis Argyros, Suet-Ping Wong, Andrew A. Miller and Richard Harbottle
Mol Ther 13: S199-S200; doi:10.1016/j.ymthe.2006.08.590
520. ProTIS, a Method for Prediction of Insertion-Site Preferences into Chromosomes of Vectors Used for Gene Therapy
Aron M. Geurts, Christopher S. Hackett, Jason B. Bell, Tracy L. Bergemann, Lara S. Collier, Corey M. Carlson, David A. Largaespada and Perry B. Hackett
Mol Ther 13: S200-S200; doi:10.1016/j.ymthe.2006.08.591
521. Gene Transfer of an Anti-CCR5 siRNA by Sleeping Beauty (SB) Transposon System
Mayur C. Tamhane and Ramesh Akkina
Mol Ther 13: S200-S200; doi:10.1016/j.ymthe.2006.08.592
522. Neural Retina Limits Delivery Non Viral Vectors to Retinal Pigment Epithelium
Liesbeth Peeters, Niek Sanders, Koen Boussery, Johan Van de Voorde, Joseph Demeester and Stefaan De Smedt
Mol Ther 13: S200-S201; doi:10.1016/j.ymthe.2006.08.593
523. Deoxyribonuclease I and Endonuclease G Are Host Defense Enzymes Responsible for Inactivation of Foreign DNA in Kidney Tubular Epithelial Cells
Timea Buzder, Xiaoyan Yin, Xiaoying Wang, Gaspar Banfalvi and Alexei G. Basnakian
Mol Ther 13: S201-S201; doi:10.1016/j.ymthe.2006.08.594
524. Analysis of Unique Proteins Bound to Sequentially Injected DOTAP:DNA Vectors
Christine C. Conwell and Leaf Huang
Mol Ther 13: S201-S201; doi:10.1016/j.ymthe.2006.08.595
525. Mutants of phiC31 Integrase with Increased Efficiency and Specificity
Annahita Keravala, Solomon Lee, Eric C. Olivares, Bhaskar Thyagarajan, Alfonso Farruggio, Vanessa E. Gabrovsky and Michele P. Calos
Mol Ther 13: S201-S202; doi:10.1016/j.ymthe.2006.08.596
526. Induction of Apoptosis in Melanoma Cell Lines by the Noxa Gene
Mohamed Hassan, Amine Alaoui, Alireza Mirmohammadsadegh, Alessandra Marini, Sandeep Nambiar and Ulrich R. Hengge
Mol Ther 13: S202-S202; doi:10.1016/j.ymthe.2006.08.597
527. Pharmaceutical Plasmid Manufacturing: Development of Economical and Innovative Process Solutions
Joachim Schorr, Markus Mueller, Juergen Hubbuch and Andreas Frerix
Mol Ther 13: S202-S202; doi:10.1016/j.ymthe.2006.08.598
528. Significant Silencing Effect of a Multifunctional Envelope-Type Nano Device Encapsulating Antisense Oligodeoxynucleotide and Double-Stranded siRNA
Kentaro Kogure, Yoshio Nakamura, Ikramy A. Khalil, Shiroh Futaki and Hideyoshi Harashima
Mol Ther 13: S202-S203; doi:10.1016/j.ymthe.2006.08.599
529. Development of Novel Systemic Gene Delivery System for Cancer Therapy with Tumor-Specifically Cleavable PEG-Lipid
Hiroto Hatakeyama, Hidetaka Akita, Kentaro Kogure, Motoi Oishi, Yukio Nagasaki, Hideo Kobayashi, Hiroshi Kikuchi and Hideyoshi Harashima
Mol Ther 13: S203-S203; doi:10.1016/j.ymthe.2006.08.600
530. The Effects DNA Molecular Weights and Conformations on Cell Uptake and the Binding Interaction with Cationic Polymers Used for Non-Viral Gene Delivery
Charlie Y.-M. Hsu, Cezary Kucharski and Hasan Uludag
Mol Ther 13: S203-S204; doi:10.1016/j.ymthe.2006.08.601
531. Complexes of DNA-Cationic Liposomes with Baculovirus GP64 Envelope Fusion Protein Vesicles Demonstrate Enhanced Transfection Efficiency
Ghiabe H. Guibinga, Shaochun Song, Jeanne Loring and Theodore Friedmann
Mol Ther 13: S204-S204; doi:10.1016/j.ymthe.2006.08.602
532. An Inducible Fed-Batch Fermentation Process for Scale-Up and Production of DNA Vaccines and Gene Medicines
Aaron E. Carnes, James A. Williams and Clague P. Hodgson
Mol Ther 13: S204-S204; doi:10.1016/j.ymthe.2006.08.603
533. Recombinant (KHG)6-FGF2 Biopolymer for Targeted Gene Transfer
Arash Hatefi and Hamid Ghandehari
Mol Ther 13: S204-S205; doi:10.1016/j.ymthe.2006.08.604
534. Silk-Elastinlike Polymers for Matrix-Mediated Adenoviral Gene Delivery
Arash Hatefi and Hamid Ghandehari
Mol Ther 13: S205-S205; doi:10.1016/j.ymthe.2006.08.605
535. Physicochemical and Transfection Properties of Cationic Hydroxyethylcellulose/DNA Nanoparticles
Farzaneh Fayazpour, Bart Lucas, Carmen Alvarez-Lorenzo, Niek Sanders, Joseph Demeester and Stefaan De Smedt
Mol Ther 13: S206-S206; doi:10.1016/j.ymthe.2006.08.606
536. Charge Switchable Helper Lipids for Gene Delivery
Mark W. Grinstaff, Carla A. Hernandez Prata, Yougen Li, Dan Luo and Tom J. MacIntosh
Mol Ther 13: S206-S206; doi:10.1016/j.ymthe.2006.08.607
537. Charge-Reversal Lipids for Gene Transfection
Mark W. Grinstaff, Carla A. Hernandez Prata, Steven R. Meyers, Philippe Barthelemy, Yougen Li, Dan Luo, Tom J. McIntosh and Stephen J. Lee
Mol Ther 13: S206-S207; doi:10.1016/j.ymthe.2006.08.608
538. DNAvaletTM Transfection Reagent
Carla Prata
Mol Ther 13: S207-S207; doi:10.1016/j.ymthe.2006.08.609
539. Unraveling the Mechanisms Underlying Silencing/Activation of Episomal Vectors In Vivo
Efren Riu, Zhi-Ying Chen and Mark A. Kay
Mol Ther 13: S207-S207; doi:10.1016/j.ymthe.2006.08.610
540. Genetic Intervention towards Improving the Long Term Outcome of CABG Using a Lipid Peptide DNA Vector System
Scott A. Irvine, Faiza Afzal, Qing H. Meng, Jimmy Ho, Andrew Wu, Jean R. McEwan and Stephen L. Hart
Mol Ther 13: S207-S208; doi:10.1016/j.ymthe.2006.08.611
541. Species-Specific Characteristics in Muscle Resistance and Their Impact on In Vivo Electroporation
Amir S. Khan, Patricia A. Brown, Melissa A. Pope and Ruxandra Draghia-Akli
Mol Ther 13: S208-S208; doi:10.1016/j.ymthe.2006.08.613
542. Development and Characterization of Ultrasound Responsive Microbubbles for Gene Delivery
Ine Lentacker, Stefaan C. De Smedt, Joseph Demeester and Niek N. Sanders
Mol Ther 13: S208-S209; doi:10.1016/j.ymthe.2006.08.614
543. Monitoring Transgene Expression by Radio-Peptide Positron Emission Tomography
Amiq Gazdhar, Murat Bilici, Erick Ayuni, Thomas Krause, Michal Hofmann and Raplh A. Schmid
Mol Ther 13: S209-S209; doi:10.1016/j.ymthe.2006.08.615
544. PLGA Nanoparticles for DNA Vaccination |[ndash]| Waiving Complexity and Increasing Efficiency
Jacob Gvili and Marcelle Machluf
Mol Ther 13: S209-S209; doi:10.1016/j.ymthe.2006.08.616
545. Comparison between Different Tissues for Efficient and Safe DNA Electrotransfer In Vivo
Franck M. Andre and Lluis M. Mir
Mol Ther 13: S210-S210; doi:10.1016/j.ymthe.2006.08.617
546. Targeted Non-Viral Gene Delivery Using Microbubbles and Focused Ultrasound
Ahad Rahim, Sarah L. Taylor, Nigel L. Bush, Gail R. ter Haar, Jeff C. Bamber and Colin D. Porter
Mol Ther 13: S210-S210; doi:10.1016/j.ymthe.2006.08.618
547. Magnetically Driven Non-Viral Gene Delivery Efficiently Transfects Cultured Smooth Muscle Cells and Inhibits Their Growth Via Adiponectin Transgene Expression
Boris Polyak, Michael Chorny, Ivan Alferiev, Kenneth Walsh, Gary Friedman and Robert J. Levy
Mol Ther 13: S211-S211; doi:10.1016/j.ymthe.2006.08.619
548. Cellular Defense Response in Transduced and Transfected Human Tumor and Primary Cell Lines
Riikka Pellinen, Outi Rautsi, Saara Lehmusvaara, Sillanp|[auml]||[auml]| Maarit, Hakkarainen Tanja, V|[auml]|h|[auml]|kangas Elisa, Yl|[auml]|-herttuala Seppo, Hinkkanen Ari, Julkunen Ilkka and Wahlfors Jarmo
Mol Ther 13: S211-S211; doi:10.1016/j.ymthe.2006.08.620
549. Ultrasound with Microbubbles Enhances Gene Expression of Plasmid DNA Delivered through Portal Vein Injection
Zhenping Shen, Andrew A. Brayman, Liping Chen and Carol H. Miao
Mol Ther 13: S212-S212; doi:10.1016/j.ymthe.2006.08.621
550. Delivery of Oligodeoxynucleotides into Human Saphenous Veins and the Adjunct Effect of Ultrasound and Microbubbles
Tetsuya Kodama, Peng H. Tan, Andrew J.T. George and Martin J.K. Blomley
Mol Ther 13: S212-S212; doi:10.1016/j.ymthe.2006.08.622
551. The Use of Electroporation To Transfer Plasmids to the Lung Results in Reduced TLR9 Signaling and Inflammation
Rui Zhou, James E. Norton, Ning Zhang and David A. Dean
Mol Ther 13: S212-S213; doi:10.1016/j.ymthe.2006.08.623
552. Collateral Circulation under Cerebral Ischemia by Hypoxia Inducible Factor Naked DNA in Rat Indirect-Bypass Model
Mitsuhiro Anan, Tatsuya Abe, Takeshi Matsuda, Ryo Inoue, Keisuke Ishii, Minoru Fujiki and Hidenori Kobayashi
Mol Ther 13: S213-S213; doi:10.1016/j.ymthe.2006.08.624
553. Development of Echo-Contrast Gas Entrapping Liposome as Gene and siRNA Delivery Tool
Yoichi Negishi, Tetsuya Fukuyama, Yoko Endo, Ryo Suzuki, Kumiko Tanaka, Kaori Sawamura, Tomoko Takizawa, Kazuo Maruyama and Yukihiko Aramaki
Mol Ther 13: S213-S213; doi:10.1016/j.ymthe.2006.08.625
554. Improved Efficiency of Gene Expression Using the Stiletto|[trade]| Endocardial Direct Injection Catheter
Samuel J. Epstein, Wendy Naimark, Maria Palasis, Kian K. Poh, Tengiz Tkebuchava, Corinne Luedemann and Douglas Losordo
Mol Ther 13: S213-S214; doi:10.1016/j.ymthe.2006.08.626
555. Large-Scale, Flow-Based Electroporation To Deliver Engineered Zinc Finger Protein Nucleases That Mediate High-Efficiency Disruption of the Human CCR5 Gene
Michael C. Holmes, Linda Liu, Elena Perez, Linhong Li, Rama Shivakumar, Cornell Allen, Olga Liu, Jeffrey C. Miller, Fyodor D. Urnov, Kenneth Kim, Edward J. Rebar, Dale Ando, Philip D. Gregory, James Riley, Madhusudan Peshwa and Carl June
Mol Ther 13: S214-S214; doi:10.1016/j.ymthe.2006.08.627
556. Proteasome Inhibitors Increase Cationic-Lipid Mediated Gene Transfer in A549 Cells In Vitro
Uta Griesenbach, Maresa Brake, Aaron Gardner and Eric W.F.W. Alton
Mol Ther 13: S214-S214; doi:10.1016/j.ymthe.2006.08.628
557. A Study of AAV2/1/SERCA2a Delivered Via the V-Focus Cardiac Delivery System in an Ovine Pacing Model of Heart Failure
Melissa J. Byrne, David Kaye and John M. Power
Mol Ther 13: S214-S215; doi:10.1016/j.ymthe.2006.08.629
558. High Efficiency Transfection of Primary Cells for Basic Research and Gene Therapy
Hans-Guenter Bruenker
Mol Ther 13: S215-S215; doi:10.1016/j.ymthe.2006.08.630
559. A Pseudo-Exon Derived from an Intronic Insertion is Responsible for Duchenne-Like Muscular Dystrophy in the Welsh Corgi Dog
Bruce F. Smith and Joseph N. Kornegay
Mol Ther 13: S215-S215; doi:10.1016/j.ymthe.2006.08.632
560. GNE Gene Replacement in Hereditary Inclusion Body Myopathy
Phillip B. Maples, Daniel Darvish, Gregory Nemunaitis, Esther Chang, Julie Ogden and John Nemunaitis
Mol Ther 13: S215-S216; doi:10.1016/j.ymthe.2006.08.633
Abstracts
561. Novel Tissue-Specific Regulatory Cassettes Direct High-Level Transgene Expression in Skeletal and Cardiac Muscle
Maja Z. Salva, Charis L. Himeda, Phillip Tai, Eiko Nishiuchi, Eric E. Finn, James M. Allen, Paul Gregorevic, Michael J. Blankinship, Leonard A. Meuse, Jeffrey S. Chamberlain and Stephen D. Hauschka
Mol Ther 13: S216-S216; doi:10.1016/j.ymthe.2006.08.634
562. Ex Vivo Gene Therapy for Duchenne Muscular Dystrophy: Lentiviral Vectors, Exon Skipping and PhiC31 Integrase Approaches
Simon P. Quenneville, Pierre Chapdelaine, Joel Rousseau and Jacques P. Tremblay
Mol Ther 13: S216-S216; doi:10.1016/j.ymthe.2006.08.635
563. Correction of Glycogen Storage Disease Type II by Systemic Delivery of an AAV2/8 Vector Containing a Muscle-Specific Promoter
Baodong Sun, Ping Li, Brown Talmage, Bird Andrew, Zhen Yan and Dwight D. Koeberl
Mol Ther 13: S217-S217; doi:10.1016/j.ymthe.2006.08.636
564. Correction of Hyposialylation in Hereditary Inclusion Body Myopathy, by Ex-Vivo Therapy
Zo|[eacute]| Coulombe, Dominic Gagn|[eacute]| and Jacques P. Tremblay
Mol Ther 13: S217-S217; doi:10.1016/j.ymthe.2006.08.637
565. Acceleration of Fracture Healing with Adenovirally Transduced Human BMP-2 and -6 Genes in Horse Metatarsal Osteotomy and Ostectomy Models
Akikazu Ishihara, Alicia L. Bertone, Alan L. Litsky, John S. Mattoon and Stephen E. Weisbrode
Mol Ther 13: S217-S218; doi:10.1016/j.ymthe.2006.08.638
566. Delaying the Onset of Diabetes in the NOD Mouse Using Exosomes Derived from Dendritic Cells Transfected with Adenoviral Vectors
Melanie A. Ruffner, Seon Hee Kim, Nicole R. Bianco, William J. Shufesky, Nick Giannoukakis, Adrian E. Morelli and Paul D. Robbins
Mol Ther 13: S218-S218; doi:10.1016/j.ymthe.2006.08.639
567. Adeno-Associated Virus Vector 8 (AAV8) Provides Efficient Gene Delivery to Skeletal Muscles In Utero by Systemic Adminstration
Bhanu Munil Koppanati, Juan Li, Bing Wang, Xiao Xiao and Paula Ruth Clemens
Mol Ther 13: S218-S218; doi:10.1016/j.ymthe.2006.08.640
568. Ex Vivo Mesenchymal Stem Cell Therapy with rAAV2 Encoding BMP-2 Enhances Bone Regeneration in Ovariectomized Mouse Model
Sanjay Kumar, Tim R. Nagy and Selvarangan Ponnazhagan
Mol Ther 13: S219-S219; doi:10.1016/j.ymthe.2006.08.641
569. Gene Therapy of Uterine Leiomyoma: Adenovirus-Mediated Herpes Simplex Virus Thymidine Kinase/Ganciclovir Treatment Inhibits Growth of Human and Rat Leiomyoma Cells In Vitro and in a Nude Mouse Model
Salama A. Salama, Marwa W. Kamel, Gregory M. Christman, Hui Q. Wang and Ayman A. Al-Hendy
Mol Ther 13: S219-S219; doi:10.1016/j.ymthe.2006.08.642
570. Ectopic Expression of Adenoviral Smad7 Significantly Reduces Hypertrophic Scarring in Rabbit Ears by Abrogating TGF|[beta]|1 Signalling
Juergen Kopp, Harun Seyhan, Katrin Messingschlager, Vanessa Pe|[ntilde]|a de Bender and Raymund E. Horch
Mol Ther 13: S219-S220; doi:10.1016/j.ymthe.2006.08.643
571. Increasing BMP Responsiveness in Human Mesenchymal Stem Cells In-Vitro by Delivery of the Osteoinductive LMP-1 Gene
Manjula Viggeswarapu, Maggie Bargouti, Mesfin Teklemariam, Chantrice Rogers, Liping Zhu, Nancy Baker, Louisa F. Titus and Scott D. Boden
Mol Ther 13: S220-S220; doi:10.1016/j.ymthe.2006.08.644
572. rAd-p21 To Reduce Excessive Dermal Scarring: Efficacy, Expression, and Tensile Strength in Animal Models
David W. Kang, Dan-Ling Gu, L. David Looper, Barry J. Sugarman, Erlinda M. Quijano and Monica L. Zepeda
Mol Ther 13: S220-S220; doi:10.1016/j.ymthe.2006.08.645
573. Enhanced Level of Gene Correction Mediated by Oligonucleotides Containing CpG Modification in the mdx Mouse Model for Duchenne Muscular Dystrophy
Carmen Bertoni, Arjun Rustagi and Thomas A. Rando
Mol Ther 13: S221-S221; doi:10.1016/j.ymthe.2006.08.646
574. Models of Cancer Cachexia: Treatment with Inhibition of NF-kB
Jad R. Maamary, Zhilong Jiang and Paula R. Clemens
Mol Ther 13: S221-S221; doi:10.1016/j.ymthe.2006.08.647
575. Correction of Ventilation in Glycogen Storage Disease Type II Mice after Gel-Mediated Delivery of Adeno-Associated Virus Serotype 1 Vectors
Cathryn Mah, Lara R. DeRuisseau, Christina A. Pacak, Melissa A. Lewis, David D. Fuller and Barry J. Byrne
Mol Ther 13: S221-S222; doi:10.1016/j.ymthe.2006.08.648
576. Hypoxic Adipocytes Support Early Heterotopic Bone Formation
Elizabeth A. Olmsted-Davis, Francis H. Gannon, Zbigniew Gugala, John A. Hipp, Christine Foultier-Dilling, Michael H. Heggeness and Alan R. Davis
Mol Ther 13: S222-S222; doi:10.1016/j.ymthe.2006.08.649
577. Inducible Regulation of Runx2-Stimulated Osteogenesis
Charles A. Gersbach, Joseph M. Le Doux, Robert E. Guldberg and Andres J. Garcia
Mol Ther 13: S222-S223; doi:10.1016/j.ymthe.2006.08.650
578. Suppression of Inflammation Following Intramuscular Administration of Pseudotyped AAV-TNFR:Fc Vectors in a Rat Model of Arthritis
Haim Burstein, Kurt Lustig and Ziv Sandalon
Mol Ther 13: S223-S223; doi:10.1016/j.ymthe.2006.08.651
579. Non-Invasive Measurement of Maximal Strength in the Normal and Dystrophic Dog Quadriceps Using Magnetic Stimulation of the Femoral Nerve
Frederick J. Balzer, Martin K. Childers, Janet R. Bogan, Daniel J. Bogan, Joe N. Kornegay and Hansell H. Stedman
Mol Ther 13: S223-S223; doi:10.1016/j.ymthe.2006.08.652
580. Gene Therapy of Chronic Hepatitis B Infection Using a High-Capacity Adenovirus Expressing Interleukin 12 under the Control of a Liver Specific Mifepristone-Inducible Promoter
Julien S. Crettaz, Pedro Berraondo, Laura Ochoa, Astrid Paneda, Itziar Otano, Cristina Olague, Africa Vales, Stefan Kochanek, Jesus Prieto and Gloria Gonzalez-Aseguinolaza
Mol Ther 13: S224-S224; doi:10.1016/j.ymthe.2006.08.654
581. IL-23 Is Required for B-Cell Memory after CD40 Ligand-Modified Dendritic Cell Vaccination
Mingquan Zheng, Jolia A. Bindas, Rekha Rapaka and Jay K. Kolls
Mol Ther 13: S224-S224; doi:10.1016/j.ymthe.2006.08.655
582. CNS Gene Delivery Targeting CCR3 Protects Brain Microglia from HIV-1
Lokesh Agrawal and David S. Strayer
Mol Ther 13: S224-S225; doi:10.1016/j.ymthe.2006.08.656
583. Evaluation of a pDNA-Based Anthrax Vaccine and Immune Correlates of Protection in Mice and Non-Human Primates
Peggy Lalor, Vanessa Whitlow, C. Richard Lyons, Julie Lovechik, Mark R. Perry, Jane Morrow, Peter Hobart, Holly Horton, Larry Smith, David Kaslow and Alain Rolland
Mol Ther 13: S225-S225; doi:10.1016/j.ymthe.2006.08.657
584. Enhanced Inhibition of HIV Using Combinatorial Genetic Therapy Against HIV-1 Integrase Delivered by SV40 Vectors
Elena I. Marusich and David S. Strayer
Mol Ther 13: S225-S225; doi:10.1016/j.ymthe.2006.08.658
585. Improved Efficacy of DNA Vaccines for HIV and Smallpox Using Constant-Current Electroporation
Lauren Hirao, Amir S. Khan, Ruxandra Draghia-Akli and David B. Weiner
Mol Ther 13: S226-S226; doi:10.1016/j.ymthe.2006.08.659
586. Anti-HIV-1 Neutralizing Antibody Gene Delivery to Rhesus Macaques and Rodents: A Novel Vaccination Approach
K. Reed Clark, Jianchao Zhang, David C. Montefiori and Philip R. Johnson5
Mol Ther 13: S226-S226; doi:10.1016/j.ymthe.2006.08.660
587. HIV-1 Glycoprotein gp120 Induces Apoptosis in the Caudate-Putamen In Vivo: Implications for Gene Transfer of Anti-Oxidant Enzymes Using SV40 Vectors
Jean-Pierre Louboutin, Lokesh Agrawal, Beverly A.S. Reyes, Elisabeth J. van Bockstaele and David S. Strayer
Mol Ther 13: S226-S227; doi:10.1016/j.ymthe.2006.08.661
588. Hepatic HB-EGF (Heparin-Binding EGF-Like Growth Factor) Gene Therapy for Fulminant Hepatic Failure in Mice: More Potent Protective and Mitogenic Effects for Hepatocytes Than HGF (Hepatocyte Growth Factor)
Ken-ichiro Kosai, Ngin Cin Khai and Tomoyuki Takahashi
Mol Ther 13: S227-S227; doi:10.1016/j.ymthe.2006.08.662
589. Repeated Recombinant Adenovirus (rAd) Administration To Generate Mucosal Antibodies (Abs) vs Botulinum Toxin A (BoNT/A)
Marlene S. Strayer, Andrew B. Maksymowych, Carmen N. Nichols, Steven Elek, Jean-Pierre Louboutin, Lance L. Simpson and David S. Strayer
Mol Ther 13: S227-S228; doi:10.1016/j.ymthe.2006.08.663
590. Recombinant Adenovirus Vaccines Against Anthrax
Michael J. McConnell and Michael J. Imperiale
Mol Ther 13: S228-S228; doi:10.1016/j.ymthe.2006.08.664
591. Development of Anti-JC Virus |[ldquo]|Designer T Cells|[rdquo]| for Progressive Multifocal Leukoencephalopathy (PML) Immunotherapy
Wen Yang, Esther Beaudoin, Renaud A. Du Pasquier, Igor J. Koralnik and Richard P. Junghans
Mol Ther 13: S228-S229; doi:10.1016/j.ymthe.2006.08.665
592. Effective Transduction of Nondividing PBL, Monocytes and Monocyte-Derived Macrophages with SV40-Derived Vectors Protects from HIV-1 Challenge
Elena I. Marusich and David S. Strayer
Mol Ther 13: S229-S229; doi:10.1016/j.ymthe.2006.08.666
593. Combination Anti-HIV-1 Gene Therapy Simultaneously Targeting CCR5 and Rev Protein Using SV40-Derived Vectors Inhibits Replication of HIV
Alena A. Chekmasova and David S. Strayer
Mol Ther 13: S229-S229; doi:10.1016/j.ymthe.2006.08.667
594. Protection Against In Vivo Tumor Growth after Electroporation-Enhanced DNA Vaccination with the Hepatitis C Virus Non-Structural 3/4A
Rune Kjeken, Gustaf Ahlen, Jonas Soderholm, Torunn Tjelle, Iacob Mathiesen and Matti Sallberg
Mol Ther 13: S229-S230; doi:10.1016/j.ymthe.2006.08.668
595. Nasal Delivery of Adenovirus Expressing the Ebola Glycoprotein Protects Mice Against Ebola Virus in the Presence of Preexisting Immunity to the Vaccine Carrier
Maria Croyle, Heinz Feldmann, Steven Jones, James M. Wilson and Gary P. Kobinger
Mol Ther 13: S230-S230; doi:10.1016/j.ymthe.2006.08.669
596. A Novel Replication Incompetent Human Subgroup D Adenoviral Vector Based on Type 49: Manufacture on PER.C6|[reg]|, Cell Tropism and Immunogenicity
Angelique Lemckert, Jos Grimbergen, Anna Thorner, Ronald Vogels, Paul Quax, Jaap Goudsmit, Dan Barouch and Menzo Havenga
Mol Ther 13: S230-S230; doi:10.1016/j.ymthe.2006.08.670
597. DNA Vaccines: Induction of Humoral and Cellular Responses Via Skin or Muscle Immunization Enhanced by Electroporation
Lei Zhang, Georg Widera, Susan Bleecher and Dietmar Rabussay
Mol Ther 13: S231-S231; doi:10.1016/j.ymthe.2006.08.671
598. Effective Humoral and Cellular Smallpox-Immune Responses Using a Combination of Plasmids Delivered by Intramuscular Injection Followed by Constant-Current Electroporation in Rabbits
Amir S. Khan, Lauren Hirao, David B. Weiner and Ruxandra Draghia-Akli
Mol Ther 13: S231-S231; doi:10.1016/j.ymthe.2006.08.672
599. Neuron Loss Mediated by HIV-1 gp120 In Vivo: Neuroprotection Using SV40 Gene Transfer of Antioxidant Enzymes
Jean-Pierre Louboutin, Lokesh Agrawal, Beverly A.S. Reyes, Elisabeth J. van Bockstaele and David S. Strayer
Mol Ther 13: S232-S232; doi:10.1016/j.ymthe.2006.08.673
600. Transduced Cells with Lentiviral Vector Expressing gp41-Derived c-Peptide Are Protected from HIV-1 Infection
Kwang-soo Ahn, Seok Kee Chang, Dokeun Kim, Won Shin and Yeowon Sohn
Mol Ther 13: S232-S232; doi:10.1016/j.ymthe.2006.08.674
601. Potential of Gene Transfer for HIV/AIDS Therapy: Overwhelming and Repeated HIV Challenge Selects for Transduced Lymphocytes Capable of Long-Term Survival and Enduring Resistance to HIV
Elena I. Marusich and David S. Strayer
Mol Ther 13: S232-S233; doi:10.1016/j.ymthe.2006.08.675
602. Effectiveness of Gene Delivery Targeting HIV-1 Integrase in Inhibiting HIV Integration: Lack of HIV-1 Genomes in T-Lymphocytes during Repeated Challenges with HIV-1
Elena I. Marusich, Christine B. Mitchell and David S. Strayer
Mol Ther 13: S233-S233; doi:10.1016/j.ymthe.2006.08.676
604. Comparative Analysis of Different Methods for Quantitative Evaluation of Neutralizing Antibody to Ebola Virus in a Biosafety Level 2 or 4 Environment
Hideki Ebihara, Xiangguo Qiu, Steven Theriault, Matthew Klassen, Ute Stroeher, Jim Strong, Steven Jones, James M. Wilson, Heinz Feldmann and Gary Kobinger
Mol Ther 13: S233-S234; doi:10.1016/j.ymthe.2006.08.678
605. Long-Term Protection Afforded by a Single Administration of an Ad-Based Anti-Y. pestis Vaccine Against a Lethal Respiratory Challenge with Y. pestis
Maria J. Chiuchiolo, Anja Krause, Ronald G. Crystal and Julie L. Boyer
Mol Ther 13: S234-S234; doi:10.1016/j.ymthe.2006.08.679
606. Identification of a 45-aa Domain of the F12-Vif Mutant Possessing Anti-HIV Activity
Simona Porcellini, Rossella Lupo, Giuliana Vallanti, Maurizio Federico, Fulvio Mavilio and Chiara Bovolenta
Mol Ther 13: S234-S234; doi:10.1016/j.ymthe.2006.08.680
607. Novel Adeno-Associated Viruses as Vaccine Carriers for HIV-1: Evaluation in Non-Human Primates
Roberto Calcedo, Yan Zhi, Joanita M. Figueredo, Judith I. Franco, Julie C. Johnston, Rebecca L. Grant and James M. Wilson
Mol Ther 13: S234-S235; doi:10.1016/j.ymthe.2006.08.681
608. Dose Escalation of Recombinant Adenovirus-Based Influenza Virus Vaccine Encoding the Full Length Hemagglutinin (HA) of the A/Vietnam/1203/2004 (H5N1) To Immunize Na|[iuml]|ve and Ad-Immune Mice
Julia Steitz, Wentao Gao, Edward Nwanegbo, Ruben O. Donis, Jacqueline M. Katz and Andrea Gambotto
Mol Ther 13: S235-S235; doi:10.1016/j.ymthe.2006.08.682
609. Acute-Phase Toxicity Following Systemic Administration of Non-Human Primate Derived Adenoviral Vectors to Mice
Suryanarayan Somanthan, Zhe Zhang, Guang-Ping Gao, Martin W. Lock, Peter L. Bell, Soumitra Roy, Arbansjit K. Sandhi and James M. Wilson
Mol Ther 13: S235-S235; doi:10.1016/j.ymthe.2006.08.683
610. The Effect of In Vitro Antiviral Therapy on Lentiviral Transduction
Priscilla Yam, Paola Marcovecchio, Shirley Li, Jiing-Kuan Yee and John A. Zaia
Mol Ther 13: S235-S236; doi:10.1016/j.ymthe.2006.08.684
611. Induction of Persistent Passive Immunity Against Anthrax Toxin by an Adeno-Associated Virus Type rh10 Vector Expressing Anti-Protective Antigen Antibody
Bishnu P. De, Neil R. Hackett, Jian Ping Qiu, Julie L. Boyer, James M. Wilson and Ronald G. Crystal
Mol Ther 13: S236-S236; doi:10.1016/j.ymthe.2006.08.685
613. Challenging an Old Drug in a New Context: Low-Dose Cyclophosphamide in Immunogenetherapy of Cancer
Sebastian Tuve, Shaoheng Ni and Andre Lieber
Mol Ther 13: S236-S237; doi:10.1016/j.ymthe.2006.08.688
614. The Role of the Activated MAPK Pathway through the Oncogenic BRAFV600E-Mutation in the Immune Escaping Mechanism of Melanoma
Hidetoshi Sumimoto and Yutaka Kawakami
Mol Ther 13: S237-S237; doi:10.1016/j.ymthe.2006.08.689
615. Anti-Tumor Activities of IL-12 and IL-23 Are Mediated by Similar, yet Divergent, Effector Mechanisms
JaNean C. Ceidro, Euan Lockhart, Seon-Hee Kim and Paul D. Robbins
Mol Ther 13: S237-S237; doi:10.1016/j.ymthe.2006.08.690
616. Enhancement of Antitumor Activity of Interferons by RNAi-Mediated Silencing of SOCS Genes in Tumor Cells
Yuki Takahashi, Haruka Kaneda, Makiya Nishikawa and Yoshinobu Takakura
Mol Ther 13: S237-S238; doi:10.1016/j.ymthe.2006.08.691
617. Tumor Lysates Prepared from Cells Infected with a Fusogenic Oncolytic HSV Stimulates Potent Antitumor Immunity Against Primary and Metastatic Murine Mammary Carcinoma
Xinping Fu, Lihua Tao and Xiaoliu Zhang
Mol Ther 13: S238-S238; doi:10.1016/j.ymthe.2006.08.692
618. Hydrodynamic Limb Vein-Delivered Xenogeneic Plasmid DNA Cancer Vaccine Effectively Induces Antitumor Protection
Zane C. Neal, Mary Kay Bates and Hans Herweijer
Mol Ther 13: S238-S238; doi:10.1016/j.ymthe.2006.08.693
619. Tumor-Derived Chemokine MCP-1/CCL2 Is Sufficient for Mediating Tumor Tropism of Adoptively Transferred T-Cells
Christine E. Brown, Reena Vishwanath, Brenda Aguilar, WenChung Chang and Michael C. Jensen
Mol Ther 13: S239-S239; doi:10.1016/j.ymthe.2006.08.694
620. Liposome-Based Therapeutic Vaccine for Cervical Cancer
Weihsu Claire Chen and Leaf Huang
Mol Ther 13: S239-S239; doi:10.1016/j.ymthe.2006.08.695
621. Immunological Memory in a Syngeneic Model of Recurrent and Multifocal Glioblastoma
Gwendalyn D. King, James F. Curtin, Chunyan Liu, Catherine Bresee, Sarah B. Honig, Jeffery M. Zirger, Nico VanRooijen, Antoni Ribas, Robert Pechnick, Pedro R. Lowenstein and Maria G. Castro
Mol Ther 13: S239-S239; doi:10.1016/j.ymthe.2006.08.696
622. Effective Prevention of Spontaneous Lung Metastasis of AT6.3 Prostate Cancer by Intravenous Administration of Dendritic Cells Activated by Non-Transmissible Sendai Virus
Tomonori Kato, Yasuji Ueda, Yasuo Yoneyama, Akinao Matsunaga, Megumi Akizawa, Akira Komiya, Hiroyoshi Suzuki, Makoto Inoue, Mamoru Hasegawa, Tomohiko Ichikawa and Yoshikazu Yonemitsu
Mol Ther 13: S240-S240; doi:10.1016/j.ymthe.2006.08.697
623. Polymer Microparticles Delivering a Idiotype/Chemokine Fusion DNA Vaccine Generate Protective Immunity in a Mice Model of B Cell Lymphoma
Sudhir P. Kasturi, Bilal Ghosn, Kassandra S. Thomson, Hong Qin, Larry Kwak and Krishnendu Roy
Mol Ther 13: S240-S240; doi:10.1016/j.ymthe.2006.08.698
624. Conditionally Replicative Adenovirus Vector Overexpressing the ADP (E3-11.6K) Protein and Armed with Human Interferon Alpha
Elena V. Shashkova, Jacqueline F. Spencer, William S.M. Wold and Konstantin Doronin
Mol Ther 13: S240-S241; doi:10.1016/j.ymthe.2006.08.699
625. Viral Shedding after Intratumoral Injection of Adenoviral Vectors to Patients with Cancer
Gloria Gonz|[aacute]|lez-Aseguinolaza, Maria Ruiz, Cristina Olag|[uuml]|e, Jesus Prieto, Juan Ruiz and Bruno Sangro
Mol Ther 13: S241-S241; doi:10.1016/j.ymthe.2006.08.700