TABLE OF CONTENTS

Volume 13, Issue S1 (May 2006)

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Abstracts

1. Species Choice for Animal Modeling Cystic Fibrosis and Gene Therapy to the Airway

Xiaoming Liu, Ziying Yan, Meihui Luo, Liang N. Zhang, Cyndi Trygg, Carolina Smith, Keith Munson, William Guggino, Bruce Bunnell and John F. Engelhardt

Mol Ther 13: S1-S1; doi:10.1016/j.ymthe.2006.08.011

2. Identification of Different Modes of Viral Transport in the Non-Human Primate Brain after Convection-Enhanced Delivery of AAV Serotype Vectors

Marco A. Passini, Jie Bu, James C. Dodge, Lamya S. Shihabuddin, Tatyana V. Taksir, Denise A. Griffiths, John Bringas, Piotr Hadaczek, Mihaela Avramut, Seng H. Cheng and Krystof Bankiewicz

Mol Ther 13: S1-S1; doi:10.1016/j.ymthe.2006.08.012

3. Adeno-Associated Virus 2-Mediated Gene Transfer: Identification of a Cellular Protein Serine/Threonine Phosphatase Involved in Augmenting Vector Transduction Efficiency

Weihong Zhao, Jianqing Wu,, Li Zhong and Arun Srivastava

Mol Ther 13: S1-S2; doi:10.1016/j.ymthe.2006.08.013

4. Role of Notch1 in Augmenting Intracellular Trafficking and Transgene Expression of Recombinant Adeno-Associated Virus-2

Changchun Ren, April F. White and Selvarangan Ponnazhagan

Mol Ther 13: S2-S2; doi:10.1016/j.ymthe.2006.08.014

5. Mechanisms for Hairpin Loop Opening of |[ldquo]|Closed|[rdquo]| AAV-ITRs by Specific Cellular Endonuclease Activities, a Prerequisite for rAAV Vector Genome Recombinations In Vivo

Katsuya Inagaki, Theresa A. Storm, Mark A. Kay and Hiroyuki Nakai

Mol Ther 13: S2-S3; doi:10.1016/j.ymthe.2006.08.015

6. AAV8-Mediated Transgene Expression in Mice and Non-Human Primates

Hiroaki Mizukami, Jun Mimuro, Akira Ishiwata, Fumiko Ono, Takashi Matsushita, Takashi Okada, Masashi Urabe, Akihiro Kume, Keiji Terao, Yoichi Sakata and Keiya Ozawa

Mol Ther 13: S3-S3; doi:10.1016/j.ymthe.2006.08.016

7. Adeno-Associated Virus Type 2 (AAV2) Contains an Integrin alpha5beta1 Recognition Sequence Essential for Viral Cell Entry

Aravind Asokan, Julie B. Hamra, Mavis Agbandje-McKenna and Richard J. Samulski

Mol Ther 13: S3-S3; doi:10.1016/j.ymthe.2006.08.017

8. Adeno-Associated Virus 2-Mediated Gene Transfer: A Complex Interaction between Epidermal Growth Factor Receptor Protein Tyrosine Kinase Signaling and Ubiquitin/Proteasome Pathway in Transgene Expression

Li Zhong, Weihong Zhao, Jianqing Wu, Baozheng Li and Arun Srivastava

Mol Ther 13: S3-S4; doi:10.1016/j.ymthe.2006.08.018

9. Biology of rAAV8 in Mouse Liver Following Vector Administration at Birth

Katsuya Inagaki, Sally Fuess, Theresa A. Storm, Mark A. Kay and Hiroyuki Nakai

Mol Ther 13: S4-S4; doi:10.1016/j.ymthe.2006.08.019

10. Adeno-Associated Virus Type-1 Vectors Transduce Human Polarized Airway Epithelia without Polarity Preference

Ziying Yan, Diana C.M. Lei-Butters, Xiaoming Liu, Yulong Zhang, Meihui Luo, Liang Zhang, Roman Zak and John F. Engelhardt

Mol Ther 13: S4-S5; doi:10.1016/j.ymthe.2006.08.020

11. Transposition from a Gene-Deleted Adenoviral Vector Results in Phenotypic Correction in a Canine Model for Hemophilia B

Anja Ehrhardt, Hui Xu, Aaron M. Dillow, Stephen R. Yant, Timothy C. Nichols and Mark A. Kay

Mol Ther 13: S5-S5; doi:10.1016/j.ymthe.2006.08.022

12. Therapeutic Potential of the Chimeric Adenovirus 5/40 as Vector for Intestine-Directed Gene Therapy

Ester Rodriguez, Carolina Romero, Mireia Ferrer, Joan F. Burgue|[ntilde]|o, Ester Fernandez, Estel Gil, Hirofumi Hamada, Assumpcio Bosch and Miguel Chillon

Mol Ther 13: S5-S5; doi:10.1016/j.ymthe.2006.08.023

13. In Vivo Stable Transduction of Humanized Liver Tissue in Chimeric Mice Via High-Capacity Adenovirus-Lentivirus Hybrid Vector

Shuji Kubo, Miho Kataoka, Chise Tateno, Donna J. Palmer, Philip Ng, Katsutoshi Yoshizato and Noriyuki Kasahara

Mol Ther 13: S6-S6; doi:10.1016/j.ymthe.2006.08.024

14. High Efficiency and Long-Term Persistence In Vivo from a Helper Dependent Adenovirus/Epstein-Barr Virus Hybrid Vector

Sean D. Gallaher, Jose S. Gil and Arnold J. Berk

Mol Ther 13: S6-S6; doi:10.1016/j.ymthe.2006.08.025

15. Genetically Targeted Adenovirus Vector Carrying Reovirus |[sigma]|1-Based Attachment Protein for Improved Systemic Gene Delivery

Frederik H.E. Schagen, Harm C.A. Graat, Jan E. Carette, Terence S. Dermody, Michael A. vanGeer and Victor W. van Beusechem

Mol Ther 13: S6-S7; doi:10.1016/j.ymthe.2006.08.026

16. Direct Selection of Targeted Vector from a Random Peptide Library Displayed on Adenoviral Fiber Knob

Kazunori Aoki, Yoshiaki Miura, Kimiko Yoshida, Kazuteru Hatanaka, Takeshi Nishimoto, Shumpei Ohnami, Joanne T. Douglas, David T. Curiel and Teruhiko Yoshida

Mol Ther 13: S7-S7; doi:10.1016/j.ymthe.2006.08.027

17. Biodistribution, Innate Immune Response and Toxicity Following Intravenous Inoculation of Mice with Nonhuman Adenoviral Vectors

Dinesh S. Bangari, Anurag Sharma, Aseem Pandey, Harm HogenEsch and Suresh K. Mittal

Mol Ther 13: S7-S7; doi:10.1016/j.ymthe.2006.08.028

18. Comparison of Antitumor Activity of Cytosine Deaminase::Uracil Phosphoribosyl Transferase (CD::UPRT) and Purine Nucleoside Phosphorylase (PNP) Suicide Genes Using Replicative but Non-Disseminative Adenovirus Vectors

Jairo Jaime, Nadine Jabbour, William Parker, Eric Sorscher, Josephine Nalbantoglu and Bernard Massie

Mol Ther 13: S8-S8; doi:10.1016/j.ymthe.2006.08.029

19. A New, Plasmid-Based Adenoviral Vectoring System Derived from the Highly Immunogenic, Human Ad4 Strain

Zachary C. Hartman, Todd Mendelson and Andrea Amalfitano

Mol Ther 13: S8-S8; doi:10.1016/j.ymthe.2006.08.030

20. Construction and Characterization of Adenovirus Vectors Expressing Optimized Blood Stage Antigens of Plasmodium falciparum

Ping Chen, Svetlana Konovalova, Keith Limbach, Maureen E. Stefaniak, Noelle B. Patterson, Joseph J. Campo, Sheng Li, Richter King, Denise L. Doolan and Joseph T. Bruder

Mol Ther 13: S8-S9; doi:10.1016/j.ymthe.2006.08.031

21. Peptide-Targeted Ad19p-Based Adenoviral Vectors for Renal Gene Delivery

Laura Denby, Lorraine M. Work, Dan J. Von Seggern, Eugene Wu, Ela Hunt, Stuart A. Nicklin and Andrew H. Baker

Mol Ther 13: S9-S9; doi:10.1016/j.ymthe.2006.08.034

22. Creation of a Biological Pacemaker by Cell Fusion

Hee Cheol Cho, Yuji Kashiwakura and Eduardo Marb|[aacute]|n

Mol Ther 13: S9-S10; doi:10.1016/j.ymthe.2006.08.033

23. Catheter-Mediated Local Intramural Delivery of AdEC-SOD Inhibits Oxidative Stress and Reduces In-Stent Neointima by Accelerating Endothelial Cell Recovery in WHHL Rabbits Displaying Complex Human-Like Atherosclerotic Lesions

Olli Leppanen, Jan Hinrich Brasen, Tommi Heikura, Matias Inkala, Fabian Ahrens, Juha Rutanen, Anna-Liisa Levonen, Samar Basu, Mikko O. Laukkanen and Seppo Yla-Herttuala

Mol Ther 13: S10-S10; doi:10.1016/j.ymthe.2006.08.035

24. Widespread and Efficient Gene Delivery to the Heart and Liver Using AAV Serotype 9: Implications for Cardiovascular Disease and Hemophilia

Thierry VandenDriessche, Lieven Thorrez, Abel Acosta-Sanchez, Lilly Wang, Veerle Gillijns, Ma Ling, Herman Vandenburgh, Nico Mertens, Nico Callewaert, James Wilson, Desire Collen and Marinee Chuah

Mol Ther 13: S10-S11; doi:10.1016/j.ymthe.2006.08.036

25. Development and Characterization of Viral Vectors with High Specificity for Atherosclerotic Plaques

Katie M. White, Hildergard Buening, Lorraine M. Work, Michael Hallek, Stuart A. Nicklin and Andrew H. Baker

Mol Ther 13: S11-S11; doi:10.1016/j.ymthe.2006.08.037

26. Lentiviral Vector Delivery of vMIP-II Using Both Transplanted Endothelial and Progenitor Cells Enhances a Robust and Functional Angiogenesis In Vivo

Stephanie Cherqui, Camille Thorpe, Sunil M. Kurian and Daniel R. Salomon

Mol Ther 13: S11-S11; doi:10.1016/j.ymthe.2006.08.038

27. Prevention of Cardiac Remodeling and Heart Failure in Dahl-Salt Sensitive Rats by AAV Vector-Mediated Interleukin-10 Expression

Mutsuko Sarukawa, Takashi Okada, Toru Yoshioka, Takayuki Ito, Tatsuya Nomoto, Hiroaki Mizukami, Akihiro Kume, Keiji Yamamoto, Uichi Ikeda, Kazuyuki Shimada and Keiya Ozawa

Mol Ther 13: S12-S12; doi:10.1016/j.ymthe.2006.08.039

28. rAAV2/9 Mediated Gene Delivery of Acid |[alpha]|-Glucosidase Corrects the Cardiac Phenotype in a Mouse Model of Pompe Disease

Christina A. Pacak, Cathryn Mah, Kerry O. Cresawn, Melissa A. Lewis, Sean Germain and Barry J. Byrne

Mol Ther 13: S12-S12; doi:10.1016/j.ymthe.2006.08.040

29. Effect of AAV6-Mediated TIMP-2 Overexpression in a Murine Model of Heart Failure

Satsuki Mori, Xiaodong Zhu, Gregory Gibson, Benjamin Burkhead and Charles F. McTiernan

Mol Ther 13: S13-S13; doi:10.1016/j.ymthe.2006.08.041

30. Cardiac-Specific Gene Expression Using Pseudotyped AAV Vectors and the Cardiac Troponin-T Promoter

Konkal-Matt R. Prasad, Zequan Yang, Yaqin Xu, Stuart S. Berr and Brent A. French

Mol Ther 13: S13-S13; doi:10.1016/j.ymthe.2006.08.042

31. Dystrophin Expression in Muscles of Duchenne Muscular Dystrophy Patients Following High-Density Injections of Normal Myogenic Cells

Jacques P. Tremblay, Daniel Skuk, Marlyne Goulet, Brigitte Roy, Pierre Chapdelaine, Raynald Roy, Francine Dugr|[eacute]|, Jean-Pierre Bouchard, Jean-Guy Lachance, Michel Sylvain, Louise Desch|[ecirc]|nes and H|[eacute]|l|[egrave]|ne Senay

Mol Ther 13: S13-S14; doi:10.1016/j.ymthe.2006.08.044

32. Improvement of Muscle Mass Using shRNA Targeting Myostatin or Activin Receptor IIb

Julie Dumonceaux, Solenne Marie and Luis Garcia

Mol Ther 13: S14-S14; doi:10.1016/j.ymthe.2006.08.045

33. Systemic Delivery of AAV8/DC190-GAA to Pompe Mice Normalizes Muscle Pathology and Corrects Motor Function Deficits

R.J. Ziegler, M.A. Zhao, S.D. Bercury, J.A. Fidler, J.W. Foley, D. Armentano, S. Ryan, T. Taksir, D. Griffiths, L.S. Shihabuddin, R.K. Scheule and S.H. Cheng

Mol Ther 13: S14-S14; doi:10.1016/j.ymthe.2006.08.046

34. Phi C31 Integrase System Enhances Dystrophin Gene Expression in Skeletal Muscle of Mouse Models for Duchenne Muscular Dystrophy

Carmen Bertoni, Sohail Jarrahian, Thurman M. Wheeler, Yining Li, Eric C. Olivares, Michele P. Calos and Thomas A. Rando

Mol Ther 13: S14-S15; doi:10.1016/j.ymthe.2006.08.047

35. Systemic Administration of rAAV6-Microdystrophin Preserves Muscle Function and Extends Lifespan in the Dystrophin-/Utrophin- Mouse Model of Severe Muscular Dystrophy

Paul Gregorevic, Michael J. Blankinship, Elina Minami, James M. Allen, Charles E. Murry and Jeffrey S. Chamberlain

Mol Ther 13: S15-S15; doi:10.1016/j.ymthe.2006.08.048

36. Transplantation of SM/C-2.6+ Satellite Cells Transduced with Micro-Dystrophin CS1 cDNA by Lentiviral Vector into mdx Mice

Madoka Ikemoto, So-ichiro Fukada, Akiyoshi Uezumi, Satoru Masuda, Ampong Beryl Nyamekye, Hiroyuki Miyoshi, Hiroshi Yamamoto, Yuko Miyagoe-Suzuki and Shin'ichi Takeda

Mol Ther 13: S15-S15; doi:10.1016/j.ymthe.2006.08.049

37. Long-Term Expression of Mini-Human Dystrophin in Transgenic mdx Mice Improves Dystrophic Muscle Functions

Bing Wang, Juan Li, Chunlian Chen, Xiancheng Jiang, Terry O'Day, Jon Watchko and Xiao Xiao

Mol Ther 13: S16-S16; doi:10.1016/j.ymthe.2006.08.050

38. Morpholino Antisense Oligonucleotide Induced Exon Skipping Efficiently Restores Dystrophin Expression in the mdx Mouse

Dominic J. Wells, Caroline McCulley, Anna Graham, Ke Liu and Kim E. Wells

Mol Ther 13: S16-S16; doi:10.1016/j.ymthe.2006.08.051

39. Evaluation of rAAV-1 vs rAAV-8 Vectors and Their Mode of Delivery in Nonhuman Primate Skeletal Muscle

Alice Toromanoff, Yan Cherel, Jack-Yves Deschamps, Valder R. Arruda, Katherine A. High, Hansell H. Stedman, Mark E. Haskins, Fabienne Rolling, Ignacio Anegon, Philippe Moullier and Caroline Le Guiner

Mol Ther 13: S16-S17; doi:10.1016/j.ymthe.2006.08.052

40. Increased Transgene Expression of Dystrophin in mdx Muscle by RNAi-Mediated Silencing of Calpain Expression

Makiya Nishikawa, Kazuhiro Hirata, Kazuya Machida, Yuki Takahashi, Katsutoshi Yuasa, Shin'ichi Takeda and Yoshinobu Takakura

Mol Ther 13: S17-S17; doi:10.1016/j.ymthe.2006.08.053

41. Evaluation of Lung Cancer Virotherapy with Oncolytic Semliki Forest Virus Using Immunodeficient Rodent Tumor Model

Ann-Marie M|[auml]||[auml]|tt|[auml]|, Tiina Wahlfors, Katja H|[auml]|kkinen, Linda Jansson, Markus V|[auml]|h|[auml]|-Koskela, Ari Hinkkanen, Kimmo M|[auml]|kinen and Jarmo Wahlfors

Mol Ther 13: S17-S17; doi:10.1016/j.ymthe.2006.08.055

42. Resistance of Primary Ovarian Cancer Cells to Viral Oncolysis

Robert Strauss, Pavel Sova, Ying Liu, Zong Yi Li, Nicole Urban, Charles Drescher, Nancy Kiviat and Andre Lieber

Mol Ther 13: S18-S18; doi:10.1016/j.ymthe.2006.08.056

43. Long-Term T Cell Activation Following Combined In Situ Gene Therapy and Intensity-Modulated Radiotherapy Compared to Gene Therapy as Mono-Therapy in Prostate Cancer Patients

Tetsuo Fujita, Bin S. Teh, Terry L. Timme, Wei-Yuan Mai, Takefumi Satoh, Nobuyuki Kusaka, Koji Naruishi, Elmoataz Abdelfattah, Estuardo Aguilar-Cordova, Brian J. Miles, E. Brian Butler and Timothy C. Thompson

Mol Ther 13: S18-S18; doi:10.1016/j.ymthe.2006.08.057

44. Combination of Oncolytic Measles Virus Strains and Radiation Therapy Has Synergistic Activity in the Treatment of Glioblastoma Multiforme

Chunsheng Liu, Jann N. Sarkaria, Cory Allen, Paula J. Zollman, C. David James, Stephen J. Russell and Evanthia Galanis

Mol Ther 13: S19-S19; doi:10.1016/j.ymthe.2006.08.058

45. Paclitaxel-TRAIL Enhances the Distribution of Oncolytic Herpes Simplex Virus-1 in a Human Mammary Carcinoma Xenograft

Satoshi Nagano, Jean Y. Perentes, Rakesh K. Jain and Yves Boucher

Mol Ther 13: S19-S19; doi:10.1016/j.ymthe.2006.08.059

46. Phase I/II Study of Adenoviral Vector Delivery of HSV-tk Gene and the Intravenous Administration of Ganciclovir in Men with Local Recurrence of Prostate Cancer after Hormonal Therapy

Yasutomo Nasu, Haruki Kaku, Shin Ebara, Takashi Saika, Hiromi Kumon and Timothy C. Thompson

Mol Ther 13: S19-S20; doi:10.1016/j.ymthe.2006.08.060

47. A Combination Therapy of Selective Intraarterial Gendicine Infusion with Chemotherapy for Locally Advanced Head and Neck Carcinoma

Longjiang Li, Yuanding Huang, Lijuan Wang, Yi Li, Yuming Wen and Bo Han

Mol Ther 13: S20-S20; doi:10.1016/j.ymthe.2006.08.061

48. Adeno-Associated Viral (AAV) Vector- Mediated Systemic Delivery of mda-7/IL24 Inhibits Tumor Growth by Antitumor Bystander Effect

Ichiro Tahara, Koichi Miyake, Toshiyuki Kurai, Yukihiko Hirai, Eiji Uchida, Takashi Tajiri and Takashi Shimada

Mol Ther 13: S20-S20; doi:10.1016/j.ymthe.2006.08.062

49. Inhibition of Acid Ceramidase Expression by Small Interfering RNA Sensitize Human Prostae Cancer Cells to Apoptin Induced Cell Death

Xiang Liu, Guiwen Guo, Saeed N. Elojeimy, David H. Holman, Ayman Mahdy, Alicja Bielawska, Jacek Bielawski, Seymon Rubinchik, Jian-yun Dong, Thomas Keane, Mahvash Tavassoli, Yusuf A. Hannun and James N. Norris

Mol Ther 13: S21-S21; doi:10.1016/j.ymthe.2006.08.063

50. Adenoviral-Mediated Gene Transfer of Single Chain Fv 425:sTRAIL Fusion Protein Induces Target Cell Restricted Apoptosis in EGFR- Positive Tumor Cells and a Potent Bystander Effect

Hidde J. Haisma, Marike Dijkstra, Edwin Bremer and Wijnand Helfrich

Mol Ther 13: S21-S21; doi:10.1016/j.ymthe.2006.08.064

51. Clinical Study of Personalized Therapeutics Based on Genomic/Proteomic Profiling

John Nemunaitis, Neil Senzer, Jerry Shen, Phillip Maples, Donald Rao, Alex Tong, Padmasini Kumar, Joe Kuhn, Yu-An Zhang, Jian Liao, Iya Khalil, Colin Hill and Adi Gazdar

Mol Ther 13: S21-S22; doi:10.1016/j.ymthe.2006.08.066

52. A Phase 1 Dose-Escalation Trial of Intravesical CG0070 for Superficial Transitional Cell Carcinoma (TCC) of the Bladder after Bacillus Calmette-Guerin (BCG) Failure

Neil Senzer, John Nemunaitis, Michael Goldstein, James Arseneau, Don Lamm, Joe Stephenson, Harry Tsai, Kristina Neal, Junko Aimi, D.C. Yu, Daniel Maslyar, John Corman, James Mckiernan and James Burke

Mol Ther 13: S22-S22; doi:10.1016/j.ymthe.2006.08.067

53. Preliminary Results of a Pilot Phase I Clinical Trial of Adoptive Immunotherapy for B Cell Lymphoma Using CD8+ T Cells Genetically Modified To Express a Chimeric T Cell Receptor Recognizing CD20

Oliver W. Press, Jinjuan Wang, Catherine G. Lindgren, Eric Y. Chen, Ajay K. Gopal, John M. Pagel, Xiaojun Qian, Stanley R. Riddell, Philip D. Greenberg, Andrew Raubitschek and Michael C. Jensen

Mol Ther 13: S22-S23; doi:10.1016/j.ymthe.2006.08.068

54. TNFerade|[trade]| in Pancreas Cancer: Local Activation with Systemic Potential

Neil Senzer, John Nemunaitis, J. Macko and Thomas Davis

Mol Ther 13: S23-S23; doi:10.1016/j.ymthe.2006.08.069

55. Translating Preclinical Results into the Clinical Development of PV701, an Oncolytic Virus

Robert M. Lorence, M. Scot Roberts, James D. O'Neil, Pete T. Buasen, Li Zhang, William S. Groene and Michael K. Bamat

Mol Ther 13: S23-S23; doi:10.1016/j.ymthe.2006.08.070

56. The Efficacy of Replicating Virotherapy for Tumors Involves a Complex Equilibrium between Virus, Tumor and the Immune System

Rosa Maria Diaz, Feorilo Galivo, Jian Qiao, Jill Thompson, Timothy Kottke, John Bell, Glen Barber and Richard Vile

Mol Ther 13: S24-S24; doi:10.1016/j.ymthe.2006.08.071

57. Targeted Gene Delivery of Alpha-Interferon by Genetically Modified Hematopoietic Cells Inhibits Glioma Vascularization and Growth without Systemic Toxicity

Michele DePalma, Rossella Galli, Mary Anna Venneri, Letterio S. Politi, Ferdinando Pucci, Lucia Sergi Sergi, Elena Binda, Ehud Hauben and Luigi Naldini

Mol Ther 13: S24-S24; doi:10.1016/j.ymthe.2006.08.072

58. Oncolytic Measles Virus Delivery by Infected Cell Carriers |[ndash]| A Strategy To |[ldquo]|By-Pass|[rdquo]| the Pre-Existing Humoral Immune Response

Ianko D. Iankov, Boris R.A. Blechacz, Guy E. Griesmann, Mark J. Federspiel and Stephen J. Russell

Mol Ther 13: S24-S25; doi:10.1016/j.ymthe.2006.08.073

59. Targeted Gene Therapy of Malignant Glioma with Adult Stem Cells

Hrvoje Miletic, Yvonne Fischer, Tsanan Giroglou, Sara Litwak, Sandra Winkeler, Uwe Himmelreich, Werner Stenzel, Martina Deckert, Andreas H. Jacobs, Harald Neumann and Dorothee von Laer

Mol Ther 13: S25-S25; doi:10.1016/j.ymthe.2006.08.074

60. Radiation Improves Local Delivery of a Virus-Mimicking Nanostructure Complex in Tumors

Rebecca A. Abela, Liang Xu, Theodore S. Lawrence and Ming Zhang

Mol Ther 13: S25-S25; doi:10.1016/j.ymthe.2006.08.075

61. Successful Gene Therapy of a Mouse Model of Congenital Erythropoietic Porphyria with an Erythroid-Specific Lentiviral Vector

Elodie Robert, Magalie Lalanne, Isabelle Lamrissi-Garcia, Muriel Cario-Andre, Cecile Ged, Hubert De Verneuil and Francois Moreau-Gaudry

Mol Ther 13: S25-S26; doi:10.1016/j.ymthe.2006.08.077

62. Proteasome Activity Restricts Lentiviral Gene Transfer into Hematopoietic Stem Cells and Is Down-Regulated by Cytokines That Enhance Transduction

Francesca R. Santoni de Sio, Paolo Cascio, Anna Zingale, Mauro Gasparini and Luigi Naldini

Mol Ther 13: S26-S26; doi:10.1016/j.ymthe.2006.08.078

63. Long-Term Constitutive Expression of the Therapeutic Gene, IL2RG, Causes T-Cell Lymphomas in a Gene Therapy Model for XSCID

Niels-Bjarne Woods, Virginie Bottero, Manfred Schmidt, Christof von Kalle and Inder M. Verma

Mol Ther 13: S26-S27; doi:10.1016/j.ymthe.2006.08.079

64. Rescue of B Cell Development in an Animal Model of X-Linked Agammaglobulinemia (XLA) Via B Lineage-Specific Lentiviral Gene Therapy

Wenying Zhang, Stephanie Humblet-Baron, Kevin Kipp, Socheath Khim, Jordan Jarjour, Karen Sommer, Brigid Stirling, Lia Pernell and David J. Rawlings

Mol Ther 13: S27-S27; doi:10.1016/j.ymthe.2006.08.080

65. Long-Term Effects of Hematopoietic Stem Cell Gene Therapy in the Murine Model of Wiskott-Aldrich Syndrome: Persistence of Functional Correction of T Cells and Lack of Malignant Trasformation

Francesco Marangoni, Lo|[iuml]|c Dupr|[eacute]|, Samantha Scaramuzza, Cristina Panaroni, Sara Trifari, Raisa Jofra Hern|[aacute]|ndez, Adrian J. Thrasher, Anne Galy, Alessandro Aiuti, Luigi Naldini and Maria Grazia Roncarolo

Mol Ther 13: S27-S28; doi:10.1016/j.ymthe.2006.08.081

66. Gene Transfer-Mediated Expression of Murine Factor VIIa Improves Clot Formation in a Mouse Model for Bernard-Soulier Syndrome

Majed N. Aljamali, Paris Margaritis, Valder R. Arruda, Alex Schlachterman, Danielle Dunn, Jerry Ware and Katherine A. High

Mol Ther 13: S28-S28; doi:10.1016/j.ymthe.2006.08.082

67. The Chicken Hypersensitive Site (cHS4) Insulator Element Reduces Position Effects Thereby Increasing Expression from Globin Lentiviral Vectors

Paritha I. Arumugam, Jessica Scholes, Ping Xia, Natalya Perelman, Alexander Zarzuela, Jiing-Kuan Yee and Punam Malik

Mol Ther 13: S28-S28; doi:10.1016/j.ymthe.2006.08.083

68. Evidence for Correction of Mutations in the c-Kit Gene by rAAV Mediated Gene Targeting in W/Wv Mice

Arthur W. Nienhuis, John T. Gray, Serena Vayda, Amanda Cline, Marguerite V. Evans-Galea and David M. Bodine

Mol Ther 13: S29-S29; doi:10.1016/j.ymthe.2006.08.084

69. Selection of Hematopoietic Progenitor and Stem Cells in Transplanted Rhesus Macaques Using MGMT and HOXB4 Lentiviral Vectors

Yan Shou, John Gray, Brian Agricola, Zhijun Ma, Geeta K. Nair, Clinton F. Stewart, Derek A. Persons and Brian P. Sorrentino

Mol Ther 13: S29-S29; doi:10.1016/j.ymthe.2006.08.085

70. Long Term Correction of beta-Thalassemia by Transplantation of Transduced Hematopoietic Stem Cells

Annarita Miccio, Rossano Cesari, Francesco Lotti, Claudia Rossi, Francesca Tiboni, Francesca Sanvito, Maurilio Ponzoni, Samantha Routledge, Michael Antoniou and Giuliana Ferrari

Mol Ther 13: S30-S30; doi:10.1016/j.ymthe.2006.08.086

71. Alpha 1 Antitrypsin (AAT) Gene Therapy for the Prevention of Type 1 Diabetes

Sihong Song, Yuanqing Lu, Mei Tang, Bin Zhang, Clive Wasserfall, Martha Campbell-Thompson and Mark Atkinson

Mol Ther 13: S30-S30; doi:10.1016/j.ymthe.2006.08.088

72. Intravascular Interaction between Adenovirus and Platelets Promotes Adenovirus Sequestration, Degradation and Toxicity

Daniel Stone, Shaoheng Ni, Zong-Yi Li, Dmitry Shayakhmetov and Andre Lieber

Mol Ther 13: S30-S31; doi:10.1016/j.ymthe.2006.08.089

73. Cats Produce a Potent CTL Response after Neonatal Gene Therapy That Can Be Blocked with CTLA4-Ig

Katherine P. Ponder, Baomei Wang, Ping Wang, Xiucui Ma, Ramin Herati, Bin Wang, Karyn Cullen, Patty O'Donnell, Tina M. Primeau and Mark E. Haskins

Mol Ther 13: S31-S31; doi:10.1016/j.ymthe.2006.08.090

74. Cellular Immunity to Adeno-Associated Virus Capsid Attenuates Transgene Expression in the Liver

Samuel L. Murphy, Denise Sabatino, Federico Mingozzi, Shyrie Edmonson and Katherine High

Mol Ther 13: S31-S32; doi:10.1016/j.ymthe.2006.08.091

75. Protease-Activated Receptor 2 as a Novel Target for Immune Modulation for AAV-Mediated Gene Transfer to Skeletal Muscle

Stefano Baila, Christian Furlan Freguia, Danielle Dunn, Federico Mingozzi, Joerg Schuettrumpf and Valder R. Arruda

Mol Ther 13: S32-S32; doi:10.1016/j.ymthe.2006.08.092

76. In Vivo Suppression of Cytotoxic T Cell Responses by CD4+ Regulatory T Cells Activated by Hepatic Gene Transfer

Lixin Wang, Eric Dobrzynski, Julie Fitzgerald, Ou Cao and Roland W. Herzog

Mol Ther 13: S32-S32; doi:10.1016/j.ymthe.2006.08.093

77. TLR and Myd88 Signaling Pathway Is Required for the Full Induction of Host Adaptive Immune Responses to Adenoviral Vectors and Transgenes

Zhe Zhang, Yan Zhi, Joanita M. Figueredo, Roberto Calcedo, James R. Miller, Guang-Ping Gao and James M. Wilson

Mol Ther 13: S33-S33; doi:10.1016/j.ymthe.2006.08.094

78. Regulation of Immune Responses Against Factor VIII Following Nonviral Gene Transfer in Hemophilia A and FOXP3 Transgenic Mouse Models

Benjamin R. Harmeling, Steven Ziegler, Troy Torgerson, Liping Chen, Hans D. Ochs, David J. Rawlings and Carol H. Miao

Mol Ther 13: S33-S33; doi:10.1016/j.ymthe.2006.08.095

79. Systemic Administration of Lentiviral Vectors Triggers Innate Host Responses

Brian D. Brown, Ehud Hauben, Giovanni Sitia, Anna Zingale, Lucia Sergi Sergi, Lucca Guidotti, Maria Grazia Roncarolo and Luigi Naldini

Mol Ther 13: S33-S34; doi:10.1016/j.ymthe.2006.08.096

80. Pre-Existing Cytotoxic T-Lymphocyte (CTL) Responses to the AAV CAP Protein Do Not Interfere with AAV Transgene Expression in Mice

William M. Siders, Johanne Kaplan, Michael Lukason, Jacqueline Shields, Lisa Woodworth, Sam Wadsworth and Abraham Scaria

Mol Ther 13: S34-S34; doi:10.1016/j.ymthe.2006.08.097

81. Hippocampal Gene Knockdown of BACE1 by Lentiviral Gene Transfer of siRNA Reduces Amyloid Pathology and Improves Memory Performance in APP Transgenic Mice

Oded Singer, Robert A. Marr, Edward Rockenstein, Leslie Crow, Fred H. Gage, Inder M. Verma and Eliezer Masliah

Mol Ther 13: S34-S34; doi:10.1016/j.ymthe.2006.08.099

82. Cftr Gene Targeting in Murine ES Cells Mediated by the SFHR Technique

Federica Sangiuolo, Maria Favia, Lorenzo Guerra, Antonio Filareto, Maria Lucia Scaldaferri, Rosa Caroppo, Paola Spitalieri, Ruggiero Mango, Emanuela Bruscia, Dieter Gruenert, Valeria Casavola, Massimo De Felici and Giuseppe Novelli

Mol Ther 13: S34-S35; doi:10.1016/j.ymthe.2006.08.100

83. Cell-Type Specific Delivery of siRNAs with Aptamer-siRNA Chimeras

Paloma H. Giangrande, James O. McNamara, Eran Andrecheck, Eli Gilboa and Bruce A. Sullenger

Mol Ther 13: S35-S35; doi:10.1016/j.ymthe.2006.08.101

83. RNA Silencing: Role of Interferon System Components in Non-Specific Effects Induced by Chemically Synthesized Small Interfering RNAs, Enzymatically Synthesized Small Interfering RNAs and Short Hairpin RNAs

Christopher S. McAllister and Charles E. Samuel

Mol Ther 13: S35-S35; doi:10.1016/j.ymthe.2006.08.102

85. Von Willebrand Factor (VWF) Gene Targeting by Double-Strand Break Enhanced Homologous Recombination

Nicole L. Prokopishyn, Brian R. Davis, Jonathan B. Rosenberg, Michael DiCola, Jennifer Brosius, R. Michael Blaese and Richard A. Metz

Mol Ther 13: S35-S36; doi:10.1016/j.ymthe.2006.08.103

86. Inhibition of Choroidal Neovascularization In Vivo by Adenovirus Mediated Delivery of Short Hairpin RNAs Targeting Vascular Endothelial Growth Factor as a Potential Therapy for Age Related Macular Degeneration

Siobhan Cashman and Rajendra Kumar-Singh

Mol Ther 13: S36-S36; doi:10.1016/j.ymthe.2006.08.104

87. Efficient Delivery of Small Interfering RNA Targeting Pro-Inflammatory Cytokines in Experimental Arthritis

Maroun Khoury, Virginie Escriou, Pascale Louis-Plence, Dani|[egrave]|le Noel, Daniel Scherman, Christian Jorgensen, and Florence Apparailly

Mol Ther 13: S36-S36; doi:10.1016/j.ymthe.2006.08.105

88. Synthetic siRNAs for Huntington's Disease Therapy

Patrick D. Staber, Chandra Vargeese, Ines H. Martins, Barry Polisky, Alex Mas-Monteys, Scott Q. Harper and Beverly L. Davidson

Mol Ther 13: S36-S37; doi:10.1016/j.ymthe.2006.08.106

89. Gene Targeting of |[beta]|-Globin IVS2 Using Sequence-Specific Peptide Nucleic Acids

Jean Y. Kuan, Ryszard Kole, Peter E. Nielsen and Peter M. Glazer

Mol Ther 13: S37-S37; doi:10.1016/j.ymthe.2006.08.107

90. miRNA Shuttles Improve Therapeutic RNAi

Ryan L. Boudreau and Beverly L. Davidson

Mol Ther 13: S37-S37; doi:10.1016/j.ymthe.2006.08.108

91. Retroviral Vector Integrations Relate to Hematopoietic Stem Cell Gene Expression Patterns

Martijn H. Brugman, Karin Pike-Overzet, Carla Oerlemans-Bergs, Sigrid Swagemakers, Dick de Ridder, Frank J.T. Staal, Monique M.A. Verstegen and Gerard Wagemaker

Mol Ther 13: S37-S38; doi:10.1016/j.ymthe.2006.08.110

92. Gene Transfer to Ocular Stem Cells by Early Gestational Intra-Amniotic Injection of Lentiviral Vector

Masayuki Endo, Phil W. Zoltick, Daniel C. Chung, Jean Bennett and Alan W. Flake

Mol Ther 13: S38-S38; doi:10.1016/j.ymthe.2006.08.111

93. Increased Number of Lung CD34+ Sca-1+ Putative Stem Cells Mediated by Adenovirus Overexpression by Sonic Hedgehog in the Respiratory Tract of Adult Mice

Anja Krause, Ju Joh, Austen Gess, Howard Lou, Ronald G. Crystal and Stefan Worgall

Mol Ther 13: S38-S38; doi:10.1016/j.ymthe.2006.08.112

94. Modulation of Postnatal Muscle-Derived Stem Cell Fate Using siRNA

Jonathan B. Pollett, Karin A. Corsi, Jessica Tebbets, Bridget M. Deasy and Johnny Huard

Mol Ther 13: S39-S39; doi:10.1016/j.ymthe.2006.08.113

95. Effective Genetic Engineering of Human Embryonic Stem Cells Using the Sleeping Beauty Transposon System

Andrew Wilber, Jonathan L. Linehan, Xinghui Tian, R. Scott McIvor and Dan S. Kaufman

Mol Ther 13: S39-S39; doi:10.1016/j.ymthe.2006.08.114

96. Enforced HoxB4 Expressed Hematopoietic Stem Cells Transdifferentiate into Oligodendrocytes in Adult Mouse Brain

Noriko Miyake, Koichi Miyake, Sanae Hisayasu, Stefan Karlsson and Takashi Shimada

Mol Ther 13: S39-S40; doi:10.1016/j.ymthe.2006.08.115

97. Translational Studies toward Optimizing In Vivo Bone Marrow Stem Cell Gene Transfer Using Lentiviral Vector

D. Nicole Worsham, Daren Wang, Christof von Kalle, David A. Williams and Dao Pan

Mol Ther 13: S40-S40; doi:10.1016/j.ymthe.2006.08.116

98. Enrichment and Characterization of Ovarian Cancer Stem Cells

Zong Yi Li, Robert Strauss, Pavel Sova, Shaoheng Ni, Mujun Yu, Dmitry Shayakhmetov, Charles Drescher, Nicole Urban and Andre Lieber

Mol Ther 13: S40-S41; doi:10.1016/j.ymthe.2006.08.117

99. Dedifferentiation of Myotubes and Redifferentiation into an Osteogenic Lineage: A Cre-Lox System Study

Anne Olshanski, Hairong Peng, Xiao Xiao and Johnny Huard

Mol Ther 13: S41-S41; doi:10.1016/j.ymthe.2006.08.118

100. Inducible and Reversible Transgene Expression in Human Stem Cells Stably Transduced by Novel Lentiviral Vectors

Betty Y. Zhou, Zhaohui Ye, Peter Gao and Linzhao Cheng

Mol Ther 13: S41-S41; doi:10.1016/j.ymthe.2006.08.119

101. Molecular Mechanism Responsible for High Level Transgene Expression in Murine and Nonhuman Primate Liver with the Second Generation of Novel AAV Serotype Vectors

You Lu, Xun Sun, Larry T. Bish, Julie C. Johnston, Roberto Calcedo, Rebecca L. Grant, Gaung-Ping Gao and James M. Wilson

Mol Ther 13: S42-S42; doi:10.1016/j.ymthe.2006.08.121

102. Activation of the LMO2 Gene in Human Lymphoid Cells by rAAV-Mediated Targeted Insertion of a Single LTR Expression Cassette into the First Intron

Byoung Y. Ryu, John T. Gray, David M. Bodine and Arthur W. Nienhuis

Mol Ther 13: S42-S42; doi:10.1016/j.ymthe.2006.08.122

103. A Screen for Host Cellular Proteins That Interact with Adeno-Associated Virus Capsid Proteins Reveals Proteins Involved in AAV8 Transduction

Bassel Akache, Sally Fuess, Dirk Grimm and Mark A. Kay

Mol Ther 13: S42-S43; doi:10.1016/j.ymthe.2006.08.123

104. Role of the HI Loop in the Adeno-Associated Virus (AAV) Life Cycle

Nina DiPrimio, Aravind Asokan and Richard J. Samulski

Mol Ther 13: S43-S43; doi:10.1016/j.ymthe.2006.08.124

105. Interactions between Modified AAV Vectors and Alternative Cell Surface Receptors Define Intercellular Trafficking Pathways and Tranduction in Human Vascular Endothelial Cells

Matthew D. Stachler and Jeffrey S. Bartlett

Mol Ther 13: S43-S43; doi:10.1016/j.ymthe.2006.08.125

106. rAAV2 Traffics through Both the Late and Recycling Endosomes in a Dose-Dependent Fashion

Wei Ding, Liang N. Zhang, Charles Yeaman and John F. Engelhardt

Mol Ther 13: S44-S44; doi:10.1016/j.ymthe.2006.08.126

107. |[alpha]|2, 3 and |[alpha]|2,6 N-Linked Sialic Acid Facilitate Efficient Binding and Transduction by Adeno-Associated Virus Type 1 and 6

Zhijian Wu and R. Jude Samulski

Mol Ther 13: S44-S44; doi:10.1016/j.ymthe.2006.08.127

108. Study of an AAV-8 Capsid Mutant with Direct Heparin Binding Capability but Reduced Efficiency in Liver-Targeted Transduction

Xuan Shen, Hui Xu, Theresa Storm and Mark A. Kay

Mol Ther 13: S44-S45; doi:10.1016/j.ymthe.2006.08.128

109. Episomal AAV Vector Genome in the Histone-Associated Chromatin Form Is Capable of Superior Transcription with HDAC Inhibitor

Takashi Okada, Ryosuke Uchibori, Mayumi Iwata-Okada, Mutsuko Nonaka-Sarukawa, Takayuki Ito, Hiroaki Mizukami, Akihiro Kume and Keiya Ozawa

Mol Ther 13: S45-S45; doi:10.1016/j.ymthe.2006.08.129

110. Investigation of Biochemical Factors That May Influence Immunogencity of AAV2 Vectors

Bernd Hauck, Federico Mingozzi, Valder Arruda, Katherine A. High and J. Fraser Wright

Mol Ther 13: S45-S45; doi:10.1016/j.ymthe.2006.08.130

111. Post-Transcriptional Gene Silencing of Alpha-1 Antitrypsin by Small Interfering RNAs (siRNA)

Pedro E. Cruz, Alexandra Golant and Terence R. Flotte

Mol Ther 13: S45-S46; doi:10.1016/j.ymthe.2006.08.131

112. Overexpression of the Coxsackie Adenovirus Receptor (CAR) Gene Influences AAV2 Transduction in Human Trabecular Meshwork Cells

Guorong Li and Teresa Borras

Mol Ther 13: S46-S46; doi:10.1016/j.ymthe.2006.08.132

113. Transduction of Neural Cells in Primate Brain Using Adeno-Associated Virus (AAV) Serotypes 2 and 5

Eleni A. Markakis, Csaba Leranth, Jeremy Bober, R. Jude Samulski, J.E. Rabinowitz, X. Zhou, Kenneth Vives and D. Eugene Redmond Jr

Mol Ther 13: S46-S47; doi:10.1016/j.ymthe.2006.08.133

114. Revisiting rAAV Vector Integration in scid Mice: DNA-PKcs Deficiency Does Not Substantially Increase Integration Frequency in Hepatic and Non-Hepatic Tissues In Vivo

Katsuya Inagaki, Theresa A. Storm, Mark A. Kay and Hiroyuki Nakai

Mol Ther 13: S47-S47; doi:10.1016/j.ymthe.2006.08.134

115. Whole Genome Analysis Shows That AAV Integrates at Chromosome 19 AAV-S1 Sites and Other Chromosomal Sites That Frequently Share GGTC Micro-Homology with the AAV P5 Promoter

Horace R. Drew III, Linda J. Lockett and Gerald W. Both

Mol Ther 13: S47-S47; doi:10.1016/j.ymthe.2006.08.135

116. The Proposed AAV Serotypes 10 and 11 Serologically Cross-React with AAV8 and AAV4

Luk H. Vandenberghe, James R. Miller, Gaung-Ping Gao, Roberto Calcedo and James M. Wilson

Mol Ther 13: S47-S48; doi:10.1016/j.ymthe.2006.08.136

117. HSPG Binding Properties of Adeno-Associated Virus Retargeting Mutants and Consequences for Their In Vivo Tropism

Daniela Goldnau, Luca Perabo, Kathryn White, Jan Endell, Sibille Humme, Lorraine Work, Hanna Jannicki, Michael Hallek, Andrew H. Baker and Hildegard Buening

Mol Ther 13: S48-S48; doi:10.1016/j.ymthe.2006.08.137

118. In Vivo Tracking of Long Term Gene Expression of AAV1 Using Fluorescence Imaging System

Ryuichi Yoneyama, Julieta Palomeque, Kozo Hoshino, Alec M. De Grand, John V. Frangioni and Roger Joseph Hajjar

Mol Ther 13: S48-S49; doi:10.1016/j.ymthe.2006.08.138

119. Intrahepatic Injection of rAAV Serotype 2 Overcomes Gender-Related Differences on Liver Transduction

Kepa Berraondo, Julien S. Crettaz, Laura Ochoa, Astrid Paneda, Jesus Prieto, Inaki F. Troconiz and Gloria Gonz|[aacute]|lez-Aseguinolaza

Mol Ther 13: S49-S49; doi:10.1016/j.ymthe.2006.08.139

120. Tropism and Toxicity of Adeno-Associated Viral Vector Serotypes on Neurons and Glia In Vitro

Doug B. Howard, Kathleen Powers, Barry J. Hoffer, Yun Wang and Brandon K. Harvey

Mol Ther 13: S49-S49; doi:10.1016/j.ymthe.2006.08.140

121. Adenovirus Titers Determined by Quantitative Real-Time PCR Correlate with Infectious Titers

Maria A. Thomas, Peter Krajcsi, Drew L. Lichtenstein, Ann E. Tollefson and William S.M. Wold

Mol Ther 13: S49-S50; doi:10.1016/j.ymthe.2006.08.142

122. Generation of a Family of Ad5 Mutants with Slowed Packaging Kinetics but Non-Affected Packaging Efficiency

Raul Alba, Patrick Hearing, Assumpcio Bosch and Miguel Chillon

Mol Ther 13: S50-S50; doi:10.1016/j.ymthe.2006.08.143

123. Cysteine Protease Inactivation of Adenovirus Is Responsible for Thermal Stress-Induced Adenovirus Infectivity Loss

De-Min Zhu, Donna Williams and Shilu Wu

Mol Ther 13: S50-S50; doi:10.1016/j.ymthe.2006.08.144

124. Optimizing Adenoviral-Based Vaccination by Combining an RGD-Modified Capsid with a Helper-Dependent Adenovirus

Airi Harui, Michael D. Roth and Saroj K. Basak

Mol Ther 13: S50-S51; doi:10.1016/j.ymthe.2006.08.145

125. Enhancement of Virus Mediated Gene Transfer by Polycationic Compounds

Saara Lehmusvaara, Eveliina Pasanen, Outi Rautsi, Tanja Hakkarainen, Marika Ruponen and Jarmo Wahlfors

Mol Ther 13: S51-S51; doi:10.1016/j.ymthe.2006.08.146

126. Evaluation of Replication Competent and Replication Incompetent Adenovirus-Mediated Toxicity in Human Adrenocortical Cells

Urska Matkovic, Monia Pacenti, Marta Trevisan, Giulia Masi, Luisa Barzon and Giorgio Palu

Mol Ther 13: S51-S52; doi:10.1016/j.ymthe.2006.08.147

127. Modulation of Adenoviral Vector Transduction by Hyaluronan and CD44 In Vivo

Joshua N. Mallam, Saumya Chaudhuri, Patricia Chevez-Barrios, Lalita Wadhwa, Mary Y. Hurwitz and Richard L. Hurwitz

Mol Ther 13: S52-S52; doi:10.1016/j.ymthe.2006.08.148

128. Evaluation of a CD46-Transgenic Mouse as a Model for Adenovirus Distribution and Expression

Emma Andersson, Ida Grundberg, Karin Edlund and G|[ouml]|ran Wadell

Mol Ther 13: S52-S52; doi:10.1016/j.ymthe.2006.08.149

129. Adenovirus Serotype 35 Vector-Mediated Transduction in Mouse Hematopoietic Stem Cells Isolated from Human CD46-Transgenic Mice

Fuminori Sakurai, Kenji Kawabata, Takao Hayakawa and Hiroyuki Mizuguchi

Mol Ther 13: S52-S53; doi:10.1016/j.ymthe.2006.08.150

130. Insertion of Transgenes into the E3 or L3 Region To Allow Tumor Selective Expression from Armed Oncolytic Adenoviruses

Michael Robinson, Satya Yendluri, Derek Ko, Lynda Hawkins and Karin Jooss

Mol Ther 13: S53-S53; doi:10.1016/j.ymthe.2006.08.151

131. Design and Construction of an Adenovirus Vector Containing Fiber Fibritin/Canine CD40L Fibers Directed to Canine CD40-Expressing Cells

Masaharu Nakayama, Joel N. Glasgow, Bruce F. Smith, Jing Li, Nikolay Korokhov, Natalya Belousova, Kenzaburo Tani and David T. Curiel

Mol Ther 13: S53-S53; doi:10.1016/j.ymthe.2006.08.152

132. Increased GFP Gene Delivery to Human Prostate Cancer Cells Using Trancomplementing Adenoviral Vectors

Elena E. Mitrofanova, Robert C. Unfer, Martha Carvour, Molly Thrall, Jim Higginbotham, Prem Seth and Charles Link

Mol Ther 13: S53-S54; doi:10.1016/j.ymthe.2006.08.153

133. Adenovirus-Light Chain Inhibition of Growth Hormone Release from Pituitary Adenoma Cells

Thais Federici, Qingshan Teng, Mary Garrity-Moses, Christina Krudy, Jun Yang and Nicholas M. Boulis

Mol Ther 13: S54-S54; doi:10.1016/j.ymthe.2006.08.154

134. A Mechanistic and Kinetic Model for the Inactivation of Liquid-Formulated Adenoviral Vectors by the Delayed Onset of a Rapid Period of Penton Disassociation

David Frey and Cassandra Shu

Mol Ther 13: S54-S54; doi:10.1016/j.ymthe.2006.08.155

135. Replication Competent Ad11 Vectors Possess a High Potential for Human Cells Targeted Cancer Therapy

Ya-Fang Mei and Goran Wadell

Mol Ther 13: S54-S54; doi:10.1016/j.ymthe.2006.08.156

136. The Oncolytic Adenovirus Targeting to TERT and Rb Pathway Induced Specific Cytotoxicity to Tumor Cells

Rong Cai, Wei Zhang, Aiwen Dong, Kai Chen, Songbo Qiu, Xinyuan Liu and Cheng Qian

Mol Ther 13: S55-S55; doi:10.1016/j.ymthe.2006.08.157

137. Streamlined Method for the Simultaneous Construction and Purification of Multiple Recombinant Adenoviral Vectors

Thomas P. Quinn, Marylou G. Gibson, Michael Haugwitz, Michael Phelan and Andrew A. Farmer

Mol Ther 13: S55-S55; doi:10.1016/j.ymthe.2006.08.158

138. Targeted Adenoviral Vectors Expressing Soluble TGF|[beta]|RIIFc for Breast Cancer Metastasis

Zhen-Guo Wang Wang, Amanda Pister, M.B. Zafar, Sung Kim and Prem Seth

Mol Ther 13: S55-S55; doi:10.1016/j.ymthe.2006.08.159

139. Manufacture of a Replication-Selective and Enhanced-Lytic Adenovirus Vector

Moria Artlip, Sawako Ishikawa, Scott Jendrek and Dexter T.K. Poon

Mol Ther 13: S55-S55; doi:10.1016/j.ymthe.2006.08.160

140. Enhanced Cell Killing Effect of E1 Modified Adenoviruses Expressing HSV-TK Suicide Gene

Oh-Joon Kwon, Dong Hyun Ko, Jing Hwa Huang, Il-Kyu Choi, Sung-Mi Jung, Joo-Hang Kim, Byoung Chul Cho and Chae-Ok Yun

Mol Ther 13: S56-S56; doi:10.1016/j.ymthe.2006.08.161

141. Ovarian Cancer-Specific Gene Therapy by Oncolytic Adenovirus

Katsuyuki Hamada

Mol Ther 13: S56-S56; doi:10.1016/j.ymthe.2006.08.162

142. pFex: A Highly Efficient Adenoviral Vector System for Fiber Gene Modification

Shawn E. Lupold, Tarana A. Kudrolli, Wasim H. Chowdhurry and Ronald Rodriguez

Mol Ther 13: S56-S56; doi:10.1016/j.ymthe.2006.08.163

143. Development of Telomerase Specific Antineoplastic Adenovirus Telomelysin (OBP-301): Establishment of Useful Assay and Assessment for Antitumor Activity

Yuuri Hashimoto, Fuminori Teraishi, Yuichi Watanabe, Shunsuke Kagawa, Hitoshi Kawamura, Katsuyuki Nagai, Noriaki Tanaka, Yasuo Urata and Toshiyoshi Fujiwara

Mol Ther 13: S56-S56; doi:10.1016/j.ymthe.2006.08.164

144. Magnetically Responsive Nanoparticles Enhance Adenoviral Gene Delivery in Cultured Smooth Muscle Cells

Michael Chorny, Ilia Fishbein, Ivan Alferiev, Origene Nyanguile and Robert J. Levy

Mol Ther 13: S57-S57; doi:10.1016/j.ymthe.2006.08.165

145. Detection of the Primary Destabilizing Modification of Liquid-Formulated Adenoviral Vectors by Anion-Exchange High Performance Liquid Chromatography

Cassandra Shu and David Frey

Mol Ther 13: S57-S57; doi:10.1016/j.ymthe.2006.08.166

146. Development of Modified Adenovirus Vectors with Reduced Innate Immune Response

Hiroyuki Mizuguchi, Naoya Koizumi, Kenji Kawabata, Fuminori Sakurai and Takao Hayakawa

Mol Ther 13: S57-S58; doi:10.1016/j.ymthe.2006.08.167

147. Effective Gene Transfer to Human Glioma Cells Using High Capacity Adenoviral Vectors: Human Glioma Cells Express Substantial Levels of CAR and Integrin Adenoviral Co-Receptors

Marianela Candolfi, James F. Curtin, Weidong Xiong, Kurt M. Kroeger, Chunyan Liu, Altan Rentsendorj, Hasmik Agadjanian, Lali Medina-Kauwe, Philip Ng, Donna Palmer, Pedro R. Lowenstein and Maria G. Castro

Mol Ther 13: S58-S58; doi:10.1016/j.ymthe.2006.08.168

148. Characterisation of a Chimpanzee Adenovirus That Is Highly Infectious to Human Low-Passage Glioma Cells

Johan Skog, Emma Andersson, Karin Edlund, Ya-Fang Mei and G|[ouml]|ran Wadell

Mol Ther 13: S58-S58; doi:10.1016/j.ymthe.2006.08.169

149. Coxsackie and Adenovirus Receptor Binding Ablation Reduces Adenovirus Liver Tropism and Toxicity

Minjung Kim, A-Rum Yoon, Ji Young Yoo, Min-Ju Kim, Yoon-A Kang, Joo-Hang Kim and Chae-Ok Yun

Mol Ther 13: S58-S59; doi:10.1016/j.ymthe.2006.08.170

150. Metabolically Biotinylated Helper Dependent Adenovirus: A New and Rapid Approach for Targeting of High-Capacity Adenoviral Vector

Vincenzo Cerullo, Michael P. Seiler, Christopher Clarke, Aylet Erez, Michael A. Barry and Brendan Lee

Mol Ther 13: S59-S59; doi:10.1016/j.ymthe.2006.08.171

151. Treatment of Experimental Schwannomas with HSV Recombinant and Amplicon Vectors

Shilpa Prabhakar, Shanta Messerli, Samuel Rabkin, Robert Martuza and Xandra O. Breakefield

Mol Ther 13: S59-S59; doi:10.1016/j.ymthe.2006.08.174

152. Comparable Protection of Human T-Cells from High Dose Challenges of HIV-1 Using Gutless and Non-Gutless rSV40 Vectors Carrying Anti-Integrase scFv: Implications for Gene Therapy

Elena I. Marusich and David S. Strayer

Mol Ther 13: S59-S60; doi:10.1016/j.ymthe.2006.08.175

153. A Novel Gene Expression System Using Human Artificial Chromosome-HSV-1 Vectors

Daniela Moralli, Kirsty Simpson, Richard Wade-Martins and Zoia Larin Monaco

Mol Ther 13: S60-S60; doi:10.1016/j.ymthe.2006.08.176

154. Tetracycline-Inducible HSV Amplicon Vectors with Expanded Range of Gene Expression Regulation

Laryssa A. Comer, Juliet L. Fernandez, Sara M. Camp, Jessica C. Tebbets, Xandra O. Breakefield and Miguel Sena-Esteves

Mol Ther 13: S60-S60; doi:10.1016/j.ymthe.2006.08.177

155. Soluble HVEM Mediates Herpes Simplex Virus 1 (HSV-1) Infection of gD Receptor-Negative Cells

Hyunjung Baek, June-young Kyoung, Juhee Park, Kee-ho Lee, William F. Goins, Justus B. Cohen, Joseph C. Glorioso and Heechung Kwon

Mol Ther 13: S61-S61; doi:10.1016/j.ymthe.2006.08.178

156. Rapid Methods of Engineering HSV Amplicon Vectors

Kazue Kasai and Yoshinaga Saeki

Mol Ther 13: S61-S61; doi:10.1016/j.ymthe.2006.08.179

157. A Mutant Type 2 Herpes Simplex Virus Deleted for the Protein Kinase Domain of the ICP10 Gene Is a Potent Oncolytic Virus

Xinping Fu, Lihua Tao and Xiaoliu Zhang

Mol Ther 13: S61-S62; doi:10.1016/j.ymthe.2006.08.180

158. Real-Time Visualization of Neuronal Differentiation and Neurite Projection Using an Indicator HSV Amplicon Vector

Shigeru Tanaka, Kazue Kasai, E. Antonio Chiocca and Yoshinaga Saeki

Mol Ther 13: S61-S62; doi:10.1016/j.ymthe.2006.08.181

159. Novel Oncolytic HSV Armed with Platelet Factor 4, an Antiangiogenic Agent, Shows Enhanced Efficacy

Ta-Chiang Liu, Tingguo Zhang, Hiroshi Fukuhara, Toshi Kuroda, Tomoki Todo, Robert L. Martuza, Samuel D. Rabkin and Andreas Kurtz

Mol Ther 13: S62-S62; doi:10.1016/j.ymthe.2006.08.182

160. Innate Immune Responses to Viral Vectors Are Modulated by Complement Inhibitors in an Ex Vivo Model Using Whole Human Blood

Lindsay J. Stanbridge, Graciela Elgue, Javier Sanchez, Vincent Dussupt, Lucy C. Hudson, John D. Lambris, Thomas Totterman, Norman J. Maitland and Bo Nilsson

Mol Ther 13: S62-S63; doi:10.1016/j.ymthe.2006.08.183

161. Truncated Vesicular Stomatitis Virus G-Protein Improves Baculovirus Transduction Efficiency In Vitro and In Vitro

Minna U. Kaikkonen, Jani K. Raty, Kari J. Airenne, Thomas Wirth, Tommi Heikura and Seppo Yla-Herttuala

Mol Ther 13: S63-S63; doi:10.1016/j.ymthe.2006.08.184

162. Bioluminescence Imaging of a Tetanus Toxin C-Terminal Fusion Protein after Vector Delivery

Lisa Pike and Sam Wang

Mol Ther 13: S63-S63; doi:10.1016/j.ymthe.2006.08.185

163. Baculovirus-Mediated Gene Transfer in New Zealand White Rabbit Skeletal Muscle

Tommi T. Heikura, Miia M. Roschier, Anssi J. Mahonen, Hanna P. Lesch, Tuomas T. Rissanen, Olli H. Laitinen, Kari J. Airenne and Seppo Yla-Herttuala

Mol Ther 13: S63-S63; doi:10.1016/j.ymthe.2006.08.186

164. HSV-1 Vector-Based Assay To Identify Inhibitors of the Vanilloid Receptor

Rahul Srinivasan, Darren Wolfe, Shaohua Huang, David Krisky, Adrian Sculptoreanu, Peter A. Friedman, William C. de Groat and Joseph C. Glorioso

Mol Ther 13: S63-S64; doi:10.1016/j.ymthe.2006.08.187

165. Enhanced Baculovirus-Mediated Transduction of Human Cancer Cells by Tumor-Homing Peptides

Anna R. Makela, Heli Matilainen, Daniel White and Christian Oker-Blom

Mol Ther 13: S64-S64; doi:10.1016/j.ymthe.2006.08.188

166. OncoVEX: A Family of Oncolytic Herpes Simplex Viruses Optimised for Therapeutic Use

Robert S. Coffin, Binlei Liu, Han Ziqun, Magdalena Assenberg, Suzanne Thomas, Jennifer Hu and Guy Simpson

Mol Ther 13: S64-S64; doi:10.1016/j.ymthe.2006.08.189

167. Polyethyleneimines as Vehicles for Oral Gene Delivery

Eytan A. Klausner and Kam W. Leong

Mol Ther 13: S64-S65; doi:10.1016/j.ymthe.2006.08.191

168. Peptide Aldehyde Inhibitors of the Proteasome as Improved Gene Transfer Agents

Molly E. Martin, Ji-Seon Kim and Kevin G. Rice

Mol Ther 13: S65-S65; doi:10.1016/j.ymthe.2006.08.192

169. Patterned Substrate-Mediated DNA Delivery Using Soft Lithography for Neural Tissue Engineering

Tiffany L. Houchin and Lonnie D. Shea

Mol Ther 13: S65-S66; doi:10.1016/j.ymthe.2006.08.193

170. Transfected Cell Arrays for Assessment of Estrogen Receptor Activation in Breast Cancer Cells

Angela K. Pannier, Zain Bengali, Eric A. Ariazi, V. Craig Jordan and Lonnie D. Shea

Mol Ther 13: S66-S66; doi:10.1016/j.ymthe.2006.08.194

171. PEG-b-PPA/DNA Micelles for Liver Targeted-Gene Delivery

Xuan Jiang, Hui Dai, Kam W. Leong and Hai-Quan Mao

Mol Ther 13: S66-S66; doi:10.1016/j.ymthe.2006.08.195

172. Spatially-Controlled Delivery of Cyclodextrin-Based Polyplexes from Solid Surfaces

In-Kyu Park, Horst A. von Recum, Shaoyi Jiang and Suzie H. Pun

Mol Ther 13: S67-S67; doi:10.1016/j.ymthe.2006.08.196

173. Novel Cell-Specific Gene Delivery for Tumors Using a Drug or Gene Delivery System Based on Responses to Intracellular Signals (D-RECS) Concept

Yoshiki Katayama, Jeong Hun Kang, Daisuke Asai, Takeshi Mori and Takuro Niidome

Mol Ther 13: S67-S67; doi:10.1016/j.ymthe.2006.08.197

174. Chloroquine and Chloroquine Analogues in Non-Viral Delivery

Jianjun Cheng, Ryan Zeidan, Swaroop Mishra, Aijie Liu, Suzie Pun, Greg Jensen, Nathalie Bellocq, Rajan Kulkarni and Mark E. Davis

Mol Ther 13: S67-S68; doi:10.1016/j.ymthe.2006.08.198

175. Delivery Via Non-Viral Options to the Auditory Structures

Mark J. Praetorius, Christoph Klingmann, Douglas E. Brough, Peter K. Plinkert and Hinrich Staecker

Mol Ther 13: S68-S68; doi:10.1016/j.ymthe.2006.08.199

176. An Inhibitor of Fumarylacetoacetate Hydrolase (Fah) for Selection of Transplanted Hepatocytes and Gene Correction In Vivo

Karsten Wursthorn, John F. Witte, R.L. Bateman, Milton Finegold, Ronald W. McClard and Markus Grompe

Mol Ther 13: S68-S68; doi:10.1016/j.ymthe.2006.08.200

177. A Novel Class of Cationic Amphiphiles for Airway Gene Delivery

Keun-Sik Kim, Qun Li, Takeshi Suda and Dexi Liu

Mol Ther 13: S68-S69; doi:10.1016/j.ymthe.2006.08.201

178. Structure-Activity Relationships in a Library of Pyridinium Non-Viral Vectors for Gene Delivery

Marc A. Ilies, Betty H. Johnson, Aaron Miller, William A. Seitz, E. Brad Thompson and Alexandru T. Balaban

Mol Ther 13: S69-S69; doi:10.1016/j.ymthe.2006.08.202

179. In Vivo Delivery of DNA or siRNA Formulated into Nanoparticles with Linear PEI

Anne-Laure Bolcato-Bellemin, Marie-Elise Bonnet and Patrick Erbacher

Mol Ther 13: S69-S69; doi:10.1016/j.ymthe.2006.08.203

180. Transfection Efficiency of Albumin-Containing DNA/Polyethylenimine Complexes in Primary Human Respiratory Epithelial Cells and In Vivo in the Murine Airways

Sante Di Gioia, Joanna Rejman, Salvatore Carrabino, Elena Copreni, Lucia Palmieri and Massimo Conese

Mol Ther 13: S70-S70; doi:10.1016/j.ymthe.2006.08.204

181. Quantitative Evaluation of Long Term Gene Expression In Vivo after Delivery of Polyethylenimine-Conjugated Sleeping Beauty Transposon DNA

Kelly M. Podetz-Pedersen, Jason B. Bell, Terry W. Steele, Joel L. Frandsen, Thomas W. Shier, R. Scott McIvor and Perry B. Hackett

Mol Ther 13: S70-S70; doi:10.1016/j.ymthe.2006.08.205

182. Branched Chitosan Oligomers Enhance Gene Delivery In Vitro and after Lung Administration In Vivo

Mohamed M. Issa, Magnus K|[ouml]|ping-H|[ouml]|gg|[aring]|rd, Kristoffer Tommeraas, Kjell M. V|[aring]|rum, Bj|[oslash]|rn E. Christensen, Olav Smids|[oslash]|rd and Per Artursson

Mol Ther 13: S70-S71; doi:10.1016/j.ymthe.2006.08.206

183. Targeting of Muscle Cells with Functionalised Lipid Particles

Harald Heider, Sandro Rusconi and Denis Bron

Mol Ther 13: S71-S71; doi:10.1016/j.ymthe.2006.08.207

184. Novel Cationic Multivalent Lipids Show Improved Delivery of siRNA and DNA

Nathan F. Bouxsein, Kai K. Ewert, Christopher S. McAllister, Heather M. Evans, Charles E. Samuel and Cyrus R. Safinya

Mol Ther 13: S71-S71; doi:10.1016/j.ymthe.2006.08.208

185. Structural Advantage of Dendritic poly(L- lysine) in Gene Delivery In Vitro and In Vivo

Takuro Niidome, Masato Yamagata, Takayuki Iida, Takahito Kawano, Kouhei Shiba and Yoshiki Katayama

Mol Ther 13: S72-S72; doi:10.1016/j.ymthe.2006.08.209

186. Efficient In Vivo Gene Expression by DNA/ Polycation/Polyanion Ternary Complexses

Tomoko Ito, Keiko Abe, Chieko Yoshihara, Naoko Iida Tanaka and Yoshiyuki Koyama

Mol Ther 13: S72-S73; doi:10.1016/j.ymthe.2006.08.210

187. Modular Cationic Peptides as Gene Delivery Agents

Rukkumani Rajagopalan, Jennifer Xavier, Nalam M. Rao and Vijaya Gopal

Mol Ther 13: S73-S73; doi:10.1016/j.ymthe.2006.08.211

188. Internalization of Novel Delivery Vector TAT-Streptavidin into Human Cells

Johanna Rinne, Brian Albarran, Juulia Jylh|[auml]|v|[auml]|, Teemu O. Ihalainen, Pasi Kankaanp|[auml]||[auml]|, Vesa P. Hyt|[ouml]|nen, Patrick S. Stayton, Markku S. Kulomaa and Maija Vihinen-Ranta

Mol Ther 13: S73-S73; doi:10.1016/j.ymthe.2006.08.212

189. Enhanced Nuclear Import and Transfection Efficiency by Disaccharide-Modified PEIs

Takeshi Nagasaki, Toshiki Shiga, Tomomi Jinta and Seiji Shinkai

Mol Ther 13: S73-S74; doi:10.1016/j.ymthe.2006.08.213

190. Gene Delivery without Nonspecific Biological Response: Comprehensive Analysis of Cell Bioactivity Using a Novel Cationic Polymer-Based System

Kayo Masago, Keiji Itaka, Nobuhiro Nishiyama, Shigeto Fukushima and Kazunori Kataoka

Mol Ther 13: S74-S74; doi:10.1016/j.ymthe.2006.08.214

191. Design, Synthesis, and Characterization of a New Class of Quaternary Ammonium Gemini Amphiphiles for Gene Delivery

Qun Li, Guisheng Zhang, Wei Xu and Dexi Liu

Mol Ther 13: S74-S74; doi:10.1016/j.ymthe.2006.08.215

192. RGD- Functionalised Liposome for Tumour Targeting

Jianmeizi (May) Chen, Ayesha Ahmad, Andrew D. Miller, Michael Keller, Eric Perouzel and Michael R. Jorgensen

Mol Ther 13: S74-S75; doi:10.1016/j.ymthe.2006.08.216

193. Gene Transfection Using Inorganic Particle/PVA/DNA Complexes Prepared by Ultra High Pressure Technology

Tsuyoshi Kimura, Kwangoo Nam, Sihngo Mutsuo, Hidekazu Yoshizawa, Masahiro Okada, Tsutomu Furuzono, Toshiya Fujisato and Akio Kishida

Mol Ther 13: S75-S75; doi:10.1016/j.ymthe.2006.08.217

194. Development of Novel DNA Formulations Based on Polymers and Cyclodextrin for Gene Delivery to the Muscle

Caroline Roques, Andr|[eacute]| Salmon, Marc Y. Fiszman, Elias Fattal and Yves Fromes

Mol Ther 13: S75-S76; doi:10.1016/j.ymthe.2006.08.218

195. Tat Peptide Conjugates of Low Molecular Weight Polyethylenimine as Effective Non-Viral Gene Delivery Vectors

Shu Wang

Mol Ther 13: S76-S76; doi:10.1016/j.ymthe.2006.08.219

196. Genetic Manipulation of Dendritic Cells through the Use of Immunolipoplexes To Induce T Cell-Specific Tolerance In Vivo

Peng H. Tan, Robert I. Lechler, Giovanna Lombardi and Andrew J.T. George

Mol Ther 13: S76-S76; doi:10.1016/j.ymthe.2006.08.220

197. Development of Chitosan Nanoparticles for Gene Delivery System

Zhi-Hong Yang, Toshinori Sato and Yoshiyuki Koyama

Mol Ther 13: S76-S77; doi:10.1016/j.ymthe.2006.08.221

198. In Vitro and In Vivo Gene-Transferring Characteristics of Novel Cationic Lipids, DMKD(O,O|[prime]|-dimyristyl-N-lysyl aspartate) and DMKE(O,O|[prime]|-dimyristyl-N-lysyl Glutamate)

Hong Sung Kim, In Ho Song, Jong Chul Kim, Eun Jung Kim, Yeon Kyung Lee, Jung Seok Kim, Kyung Hye Koo, Doo Ok Jang and Yong Serk Park

Mol Ther 13: S77-S77; doi:10.1016/j.ymthe.2006.08.222

199. Plasmid DNA Delivery by Nanoparticule Loaded Coronary Stent

Cunxian Song, Xu Jin, Dunwan Zhu, Chao Zhang, Hongfan Sun, Linhua Zhang and Kangde Yao

Mol Ther 13: S77-S78; doi:10.1016/j.ymthe.2006.08.223

200. A Novel Non-Viral Polymer for Plasmid Delivery to Bone Marrow Stromal Cells (BMSC)

Basak A. Clements, Vanessa Incani, Cezary Kucharski, Afsaneh Lavasanifar and Hasan Uludag

Mol Ther 13: S78-S78; doi:10.1016/j.ymthe.2006.08.224

201. Selective Targeting of Nucleic Acid Nanoparticles to Hepatocytes In Vivo

Darren H. Wakefield, So Wong, David B. Rozema, Jason J. Klein and Jon A. Wolff

Mol Ther 13: S78-S78; doi:10.1016/j.ymthe.2006.08.225

202. Effect of Modification with Lipophilic Fragments and Inclusion of Endosomolytic Peptide on Transfection Efficiency Mediated by Lysine Dendrimers

Anna A. Egorova, Polina L. Il'ina, Anton V. Kiselev, Aleksandre N. Baranov, Irina I. Tarasenko, Gennadii P. Vlasov and Vladislav S. Baranov

Mol Ther 13: S78-S78; doi:10.1016/j.ymthe.2006.08.226

203. Salt Conditions during Polyplex Formation Significantly Alters Transfection

Qixin Leng, Jason Kahn, Jingsong Zhu, Puthapparampil Scaria and Archibald J. Mixson

Mol Ther 13: S79-S79; doi:10.1016/j.ymthe.2006.08.227

204. Novel Gene Transduction Technology by Credia TF

Motoyoshi Tanaka, Madoka Tonosaki, Masafumi Umekage, Tomio Konaka, Ikeda Hisafumi and Hirotsugu Uemura

Mol Ther 13: S79-S79; doi:10.1016/j.ymthe.2006.08.228

205. AAV-Mediated Gene Transfer to Muscle and Liver of MPS VI Animal Models

Alessandra Tessitore, Armida Faella, Fabiana Parisi, Mark Haskins and Alberto Auricchio

Mol Ther 13: S79-S79; doi:10.1016/j.ymthe.2006.08.230

206. Frequency and Analysis of Liver Tumors in AAV-Treated B6C3F1 Hybrid Mice

Peter L. Bell, A. David Moscioni, Robert J. McCarter, Di Wu, Guang-Ping Gao, Albert Hoang, Julio San Miguel, Xun Sun, Nelson Wivel, Steven E. Raper, Emma E. Furth, Mark L. Batshaw and James M. Wilson

Mol Ther 13: S80-S80; doi:10.1016/j.ymthe.2006.08.231

207. Long-Term Therapy for PKU in Mice by rAAV Pseudotype 8 Gene Transfer to Liver

Alexandre Rebuffat, Zhaobing Ding, Panco Georgiev and Beat Thony

Mol Ther 13: S80-S80; doi:10.1016/j.ymthe.2006.08.232

208. Sleeping Beauty Transposon-Mediated Long-Term |[alpha]|-L-iduronidase Expression and Correction of Lysosomal Pathology in the Murine Model of Mucopolysaccharidosis (MPS) Type I

Elena L. Aronovich, Jason B. Bell, Lalitha R. Belur, Roland Gunther, Brenda Koniar, David C.C. Erickson, Patricia A. Schachern, R. Scott McIvor, Chester B. Whitley and Perry B. Hackett

Mol Ther 13: S80-S81; doi:10.1016/j.ymthe.2006.08.233

209. Correction of Hunter Syndrome in the MPSII Mouse Model by AAV2/8-Mediated Gene Delivery

Monica Cardone, Vinicia Assunta Polito, Stefano Pepe, Linda Mann, Alessandra D'Azzo, Alberto Auricchio, Andrea Ballabio and Maria Pia Cosma

Mol Ther 13: S81-S81; doi:10.1016/j.ymthe.2006.08.234

210. Permanent Correction of Leptin Deficiency through Cutaneous Gene Therapy. Lentivirus but Not Retrovirus-Transduced Human Keratinocyte Orthotopic Grafts Achieve Therapeutic Systemic Leptin Levels

Laura Rico, Isabel Mirones, Blanca Duarte, Almudena Holguin, Antonio Bernad, Marcela Del Rio and Fernando Larcher

Mol Ther 13: S81-S81; doi:10.1016/j.ymthe.2006.08.235

211. Development of Helper-Dependent Adenovirus (HDAd) Vectors for Gene Therapy in the Mouse Model for Glycogen Storage Disease Type Ia (GSD-Ia)

Dwight D. Koeberl, Lopamudra Banerjee, Baodong Sun, Andrew Bird, Y.T. Chen, Kazuhiro Hiro and Lawrence Chan

Mol Ther 13: S81-S82; doi:10.1016/j.ymthe.2006.08.236

212. Delivery of Galactocerebrosidase Activity to the Peripheral Nervous System of Mice with Globoid Cell Leukodystrophy (Krabbe Disease) by Intramuscular Injection

Mohammad A. Rafi, Han Zhi Rao, Paola Luzi, Mark T. Curtis and David A. Wenger

Mol Ther 13: S82-S82; doi:10.1016/j.ymthe.2006.08.237

213. Improving the Therapeutic Index of Helper-Dependent Adenoviral Vector for Crigler-Najjar Gene Therapy

David Dimmock, Nicola Brunetti-Pierri, Viraj Mane, Donna Palmer, Arthur Beaudet and Philip Ng

Mol Ther 13: S82-S82; doi:10.1016/j.ymthe.2006.08.238

214. Dominant-Negative Interference in the Pahenu2 Mouse: Modified Forms of PAH

Andreas Zori, Dawn D. Yang, Jon-Michael Knapp, Catherine E. Charron, Jennifer E. Embury, Stacy L. Porvasnik and Philip J. Laipis

Mol Ther 13: S82-S83; doi:10.1016/j.ymthe.2006.08.239

215. Treating Hypoparathyroidism through Regulated Expression of Parathyroid Hormone in Skeletal Muscle

Maja Z. Salva and Stephen D. Hauschka

Mol Ther 13: S83-S83; doi:10.1016/j.ymthe.2006.08.240

216. Long Term Portal Vein Administration of AAV-WPRE Vector Results in Increased Incidence of Neoplastic Disease and Hepatic Pathology

Jennifer E. Embury, Catherine C. Charron, Amy E. Poirier, Andreas Zori, Russ Carmichael, Terry R. Flotte and Philip J. Laipis

Mol Ther 13: S83-S83; doi:10.1016/j.ymthe.2006.08.241

217. Comparison of Hepatic Vein and Peripheral Vein Delivery of an AAV2/8 Vector Encoding Human a-Galactosidase A to Rhesus Macaques

Bradley L. Hodges, Qiuming Chu, Jennifer B. Nietupski, Karen M. Ashe, Kristin M. Taylor, Robin J. Ziegler, Seng H. Cheng, John Marshall and Ronald K. Scheule

Mol Ther 13: S84-S84; doi:10.1016/j.ymthe.2006.08.242

218. Gene Therapy and Enzyme Replacement in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis

Michael Chang, David Sleat, Seng Cheng, Marco Passini, Peter Lobel and Beverly L. Davidson

Mol Ther 13: S84-S84; doi:10.1016/j.ymthe.2006.08.243

219. Persistent Correction of Hyperphenylalaninemia Following Liver-Directed, rAAV2/8-Mediated Gene Therapy for Murine Phenylketonuria (PKU)

Cary O. Harding, Melanie B. Gillingham, Elizabeth Daghighi, Andrew Bird and Dwight D. Koeberl

Mol Ther 13: S84-S84; doi:10.1016/j.ymthe.2006.08.244

220. AAV Mediated Gene Transfer of Smad7 in Different Models of Cystic Kidney Diseases

Andrea Keppler, Barbara Leuchs, Carolin Stump, Steven Dooley, Juergen Kleinschmidt and Norbert Gretz

Mol Ther 13: S85-S85; doi:10.1016/j.ymthe.2006.08.245

221. A New Retroviral Gene Therapy Approach for Cystinuria Research

Sreedhar Sagi, Marcus Picard-Maureau, Rudiger Dorries, Peter Alken, Maurice S. Michel and Thomas Knoll

Mol Ther 13: S85-S85; doi:10.1016/j.ymthe.2006.08.246

222. Aberrant Striatal Gene Expression in the Striatum of HPRT-Knockout Mouse

Shaochun Song, C. Ramana Bhasker, Ling Guo and Theodore Friedmann

Mol Ther 13: S85-S85; doi:10.1016/j.ymthe.2006.08.247

223. Proteomic Analysis of the Striatum of Wild Type and HPRT-Deficient Mouse

Ling T. Guo, Charles C. King, Shaochun Song and Theodore Friedmann

Mol Ther 13: S85-S86; doi:10.1016/j.ymthe.2006.08.248

224. Pyruvate Dehydrogenase Complex Deficiency Caused by the Ubiquitin-Proteasome System-Mediated Degradation in E1|[beta]| Subunit

Zongchao Han, Arun Srivastava and Peter Stacpoole

Mol Ther 13: S86-S86; doi:10.1016/j.ymthe.2006.08.249

225. A Novel Mechanism between Diabetes Mellitus Complications and Procalcitonin Gene Expression

Mehmet A. Soylemez, Ceyhan Sayar, Bilge Turkover, Guven Toksoy and Tulay Yardimci

Mol Ther 13: S86-S86; doi:10.1016/j.ymthe.2006.08.250

226. Effective Gene Therapy in an Authentic Mouse Model of Tay-Sachs Related Diseases

Begona Cachon-Gonzlez, Susan Wang, Robin Ziegler, Seng H. Cheng and Timothy M. Cox

Mol Ther 13: S86-S87; doi:10.1016/j.ymthe.2006.08.251

227. Sustained Correction of Hyperphenylalaninemia in Female Pahenu2 Mouse by a Self-Complementary Adeno-Associated Virus Vector

Akihiro Kume, Tsuyoshi Ogura, Takashi Matsushita, Hiroaki Mizukami, Masashi Urabe, Takashi Okada and Keiya Ozawa

Mol Ther 13: S87-S87; doi:10.1016/j.ymthe.2006.08.252

228. AAV Mediated Hypoxia-Inducible VEGF Expression and Neovascular Formation in Ischemic Pig Myocardium

Hua Su, Yerem Yeghiazarians, Andrew Lee, Yu Huang, Janice Arakawa-Hoyt, Jianqin Ye, Gina Orcino, William Growssman and Yuet W. Kan

Mol Ther 13: S87-S87; doi:10.1016/j.ymthe.2006.08.254

229. Use of rAAV Transduced Endothelial Progenitor Cells for the Treatment of Myocardial Infarction in Rat Model

Sabyasachi Sen, Juan Merchan, Jarrod Dean, Marcia Silver, Mary Gavin, Elizabeth Eaton, Tengiz Tkebuchava, Maasaki Ii, Young-Sup Yoon, Douglas W. Losordo and Ryuichi Aikawa

Mol Ther 13: S88-S88; doi:10.1016/j.ymthe.2006.08.255

230. In Vivo Fluorescence Tracking System for Cardiac Stem Cell Therapy

Kozo Hoshino, Hung Q. Ly, Irina Pomerantseva, Yoshiaki Takewa, Ryuichi Yoneyama, Yoshiaki Kawase, Alec M. DeGrande, John V. Frangioni and Roger J. Hajjar

Mol Ther 13: S88-S88; doi:10.1016/j.ymthe.2006.08.256

231. Gene Transfer of a Synthetic Pacemaker Channel into the Heart: A Novel Strategy for Biological Pacing

Yuji Kashiwakura, Hee Choel Cho, Ezana Azene and Eduardo Marb|[aacute]|n

Mol Ther 13: S89-S89; doi:10.1016/j.ymthe.2006.08.257

232. Short-Term, In Vivo Correction of VLCAD Deficiency in Mice: Steps toward a Gene Therapy for Cardiomyopathy

Tien Nguyen, Jan Daniels, Lawrence Merritt, Dietrich Matern, Jerry Vockley, Philip A. Wood and David B. Schowalter

Mol Ther 13: S89-S89; doi:10.1016/j.ymthe.2006.08.258

233. Conjugating Polymer Vector to Magnetic Nanobeads Enhances Local Gene Expression in the Heart

Wenzhong Li, Nan Ma, Leelee Ong, Alexander Kaminski, Peter Lorenz, Brigitte M. Putzer, Ren-Ke Li, Christof Stamm and Gustav Steinhoff

Mol Ther 13: S89-S89; doi:10.1016/j.ymthe.2006.08.259

234. Long Term Effects of pcDNA3-VEGF165 Intramyocardial Transfer after Experimental Myocardial Infarction in the Rat Scar Tissue Extracellular Matrix

Fabio D. Mataveli, Sang W. Han, Aline Mendes, Rose Kanashiro, Paulo Tucci, Helena B. Nader and Maria Aparecida S. Pinhal

Mol Ther 13: S90-S90; doi:10.1016/j.ymthe.2006.08.260

235. Herpes Simplex Virus Vector Mediated Heme Oxygenase Gene Therapy of Heart Ischemia-Reperfusion

William F. Goins, Arthur R. Frampton, Atsunori Nakao, Koji Tomiyama, David S. Clawson, James Wechuck, Shao-hua Huang, David M. Krisky, Justus B. Cohen, Noriko Murase and Joseph C. Glorioso

Mol Ther 13: S90-S90; doi:10.1016/j.ymthe.2006.08.261

236. Ultrasound-Targeted Microbubble Destruction Augments Cardiac AAV-Mediated Gene Transfer after Systemic Administration in Adult Rats

Oliver J. M|[uuml]|ller, Stefanie Schinkel, Hugo A. Katus, J|[uuml]|rgen A. Kleinschmidt and Raffi Bekeredjian

Mol Ther 13: S91-S91; doi:10.1016/j.ymthe.2006.08.262

237. Gene Expression Profiles in Diabetic Cardiomyopathy Following SERCA2a Gene Transfer

Djamel Lebeche, Susumu Sakata, Yuri Sakata, Naoya Sakata, Elie R. Chemaly, Miyako Takaki and Roger J. Hajjar

Mol Ther 13: S91-S91; doi:10.1016/j.ymthe.2006.08.263

238. Knock down Phospholamban To Improve Heart Function by AAV-Mediated shRNA

Xiaochun Lu, Guang Yang, Xiaoying Li and Xiaobing Wu

Mol Ther 13: S91-S92; doi:10.1016/j.ymthe.2006.08.264

239. Histological Measurement of Myocardial Infarct Area Does Not Provide a Sensitive Assessment of Infarct Size in a Mouse Chronic Infarct Model

Junya Takagawa, Yan Zhang, Richard E. Sievers, Neel K. Kapasi, Maelene L. Wong, Yerem Yeghiazarians, Randall J. Lee, William Grossman and Matthew L. Springer

Mol Ther 13: S92-S92; doi:10.1016/j.ymthe.2006.08.265

240. Hemiparkisonism Induced through Unilateral Expression of Adenovirus-Mediated Clostridial Light Chain Gene in the Substantia Nigra

Jun Yang, Qingshan Teng, Mary E. Garrity-Moses, Thais Federici, John Butler, Shearwood McClelland III and Nicholas M. Boulis

Mol Ther 13: S92-S92; doi:10.1016/j.ymthe.2006.08.267

241. A Dose-Ranging Study of AAV-hAADC Therapy in Parkinsonian Monkeys

John R. Forsayeth, Jamie L. Eberling, Laura M. Sanftner, Zhu Zhen, Philip Pivirotto, John Bringas, Janet Cunningham and Krystof S. Bankiewicz

Mol Ther 13: S93-S93; doi:10.1016/j.ymthe.2006.08.268

242. Neuronal Specificity of |[alpha]|-Synuclein Toxicity and the Effect of Parkin Co-Expression in Primates

Toru Yasuda, Masahiko Takada, Hideki Mochizuki and Yoshikuni Mizuno

Mol Ther 13: S93-S93; doi:10.1016/j.ymthe.2006.08.269

243. Control of Undesirable Effects of GDNF Delivered in the Striatum of Healthy Rats Using a Tetracycline-Inducible AAV1 Vector

Abdelwahed Chtarto, Xin Yang, Mansoor Sharifi, Olivier Bockstael, Enni Lehtonen, David Blum, Laurence Abeloos, Jean-Marie Jaspar, Thierry Velu, Jacques Brotchi, Marc Levivier and Liliane Tenenbaum

Mol Ther 13: S93-S93; doi:10.1016/j.ymthe.2006.08.270

244. New Gene Therapy for Parkinson's Disease by Down Regulation of |[alpha]|-Synuclein

Hideki Mochizuki, Hiromi Hayashita-Kinoh, Masanori Yamada and Yoshikuni Mizuno

Mol Ther 13: S93-S94; doi:10.1016/j.ymthe.2006.08.271

245. Delivery of IGF-1 in the Spinal Cord of a Mouse Model of ALS after Intraparenchymal Injection of an Adeno-Associated Vector

Christine Haenggeli, Angelo C. Lepore, Natalie Perez, Brian K. Kaspar and Jeffrey D. Rothstein

Mol Ther 13: S94-S94; doi:10.1016/j.ymthe.2006.08.272

246. Efficient Gene Transfer to Peripheral Nervous System Via Systemic Delivery of AAV Vectors

Chunping Qiao, Jianbin Li, Tong Zhu, Bing Wang, Juan Li, and Xiao Xiao

Mol Ther 13: S94-S94; doi:10.1016/j.ymthe.2006.08.273

247. Devising A|[beta]|-Specific Passive Immunization Strategies for Alzheimer's Disease Using rAAV Vector-Mediated scFv Antibody Delivery

Kelly L. Fowlkes, Michael A. Mastrangelo, Wade C. Narrow, Yona Levites, Todd E. Golde, Howard J. Federoff and William J. Bowers

Mol Ther 13: S94-S95; doi:10.1016/j.ymthe.2006.08.274

248. Revealing the Role(s) of TNF-alpha in Early Alzheimer's Disease Via rAAV-Mediated Hippocampal Gene Transfer in a Triple Transgenic Mouse Model

Michelle C. Janelsins, Michael A. Mastrangelo, Keigan M. Park, Kelly L. Fowlkes, Maria Kinsky, Wade C. Narrow, Salvatore Oddo, Frank M. LaFerla, Howard J. Federoff and William J. Bowers

Mol Ther 13: S95-S95; doi:10.1016/j.ymthe.2006.08.275

249. Fusion Intrabodies as Anti-Huntington Gene Therapy

Julie McLear, Jack Webster, Nikolas Webster and Anne Messer

Mol Ther 13: S95-S95; doi:10.1016/j.ymthe.2006.08.276

250. Protection Against Huntington's Diease Progression: AAV-Mediated Delivery of Biotherapeutics

Adrian P. Kells, Rebecca A. Henry, Stephanie M. Hughes, Richard L.M. Faull and Bronwen Connor

Mol Ther 13: S95-S96; doi:10.1016/j.ymthe.2006.08.277

251. Gene-Based Interferon-Beta Therapy for Experimental Autoimmune Encephalomyelitis

Ritika Jaini, Drew Hannaman, Justin M. Johnson, Robert M. Bernard, Cengiz Z. Altuntas, Maida M. de las Alas, Pavani Kesaraju, Alain Luxembourg, Claire F. Evans and Vincent K. Tuohy

Mol Ther 13: S96-S96; doi:10.1016/j.ymthe.2006.08.278

252. Targeted Transgene Integration of the Human ATM cDNA Mediated by HSV/AAV Hybrid Amplicon Vector

Jocelyn D. Sanford, Angelika Oehmig, Katherine F. Perry, Xandra O. Breakefield and Maria L. Cortes

Mol Ther 13: S96-S96; doi:10.1016/j.ymthe.2006.08.279

253. AAV Delivery of a Trans-Splicing RNA Re-Directs SMN2 Splicing and Results in Increased Full-Length SMN

Tristan H. Coady, Monir Shababi and Christian L. Lorson

Mol Ther 13: S97-S97; doi:10.1016/j.ymthe.2006.08.280

254. Protecting the CNS Using AntiOxidant Gene Transfer: HIV-1 Glycoprotein gp120 Induces Blood-Brain Barrier Abnormalities That May Be Prevented by rSV40 Gene Transfer of AntiOxidant Enzymes

Jean-Pierre Louboutin, Beverly A.S. Reyes, Lokesh Agrawal, Elisabeth J. van Bockstaele and David S. Strayer

Mol Ther 13: S97-S97; doi:10.1016/j.ymthe.2006.08.281

255. Preventing In Vivo Neurotoxicity Caused by HIV-1 Gp120 Using SV40 Vector Delivery of the Anti-Oxidant Enzymes Superoxide Dismutase and Glutathione Peroxidase

Lokesh Agrawal, Jean-Pierre Louboutin, Beverly A.S. Reyes, Elisabeth Van Bockstaele and David S. Strayer

Mol Ther 13: S97-S98; doi:10.1016/j.ymthe.2006.08.282

256. Novel Therapeutic Strategy for Ischemic Stroke by Bone Marrow Stromal Cells and Ex Vivo HGF and FGF2 Genes Transfer with Replication-Incompetent HSV-1 Vector

Naosuke Nonoguchi, Ming-Zhu Zhao, Naokado Ikeda, Yoshihito Miki, Daisuke Furutama, Fumiharu Kimura, Mari Dezawa, Hiroshi Funakoshi, Robert S. Coffin, Shin-ichi Miyatake and Toshihiko Kuroiwa

Mol Ther 13: S98-S98; doi:10.1016/j.ymthe.2006.08.283

257. VEGF Gene Transfered Bone Marrow Stromal Cells by Replication-Deficiet Herpes Simplex Virus Type-1 (HSV-1) Vector Can Improve the Neurological Deficits and Reduce the Infaction in Rat Ischemic Brain

Yoshihito Miki, Naosuke Nonoguchi, Naokado Ikeda, Ming-Zhu Zhao, Daisuke Furutama, Robert S. Coffin, Naosuke Nonoguchi and Shin-ichi Miyatake

Mol Ther 13: S98-S99; doi:10.1016/j.ymthe.2006.08.284

258. CNS-Directed Antioxidant Enzyme Delivery: Protecting Neurons from Oxidative Stress and Apoptosis Induced by HIV-1

Lokesh Agrawal, Jean-pierre Louboutin and David S. Strayer

Mol Ther 13: S99-S99; doi:10.1016/j.ymthe.2006.08.285

259. Plasmid DNA Encoding the Anti-Inflammatory Cytokine Gene, Interleukin-10 (IL-10) for Chronic Pain Control: Taking Advantage of Nuclear Scaffold/Matrix Attachment Regions

Erin D. Milligan, Stephen J. Langer, Travis S. Hughes, Evan M. Sloane, John H. Mahoney, Brian M. Jekich, Steven F. Maier, Leslie A. Leinwand and Linda R. Watkins

Mol Ther 13: S99-S99; doi:10.1016/j.ymthe.2006.08.286

260. ITRs Necessary for IL-10 Encoding Naked Plasmid Induced Reversal of Chronic Pain State in Rat

T.S. Hughes, S.J. Langer, E.M. Sloane, J. Mahoney, B. Jekich, K.W. Johnson, R.E. Chavez, E.D. Milligan, L.R. Watkins and L.A. Leinwand

Mol Ther 13: S100-S100; doi:10.1016/j.ymthe.2006.08.287

261. In Vivo Over-Expression of Fractalkine, a Putative Neuron-to-Glia Signal, To Characterize Underlying Mechanisms of Neuropathic Pain

Stephen J. Langer, David Busha, Erin D. Milligan, Travis S. Hughes, Julie Wieseler-Frank, Linda R. Watkins and Leslie A. Leinwand

Mol Ther 13: S100-S100; doi:10.1016/j.ymthe.2006.08.288

262. Delivery of CCL21 to Metastatic Disease Improves the Efficacy of Adoptive T Cell Therapy

Uma Thanarajasingam, Laura Sanz Alcober, Rosa Maria Diaz, Jian Qiao, Luis Sanchez-Perez, Timothy Kottke, Jill Thompson and Richard Vile

Mol Ther 13: S100-S101; doi:10.1016/j.ymthe.2006.08.316

263. Antigen-Specific and MHC-Independent Tumor Cell Lysis by Redirected Human CD4+ T Cells Grafted with an Antibody-Type Immunoreceptor

Andreas Hombach, Heike Koehler, Gunter Rappl and Hinrich Abken

Mol Ther 13: S101-S101; doi:10.1016/j.ymthe.2006.08.317

264. Immune Gene-Therapy of Cancer Using Redirected Na|[iuml]|ve or Effector Lymphocytes

Dinorah Friedmann-Morvinski, Tova Waks and Zelig Eshhar

Mol Ther 13: S101-S101; doi:10.1016/j.ymthe.2006.08.318

265. Non-Viral Delivery of Interleukin-2 and Soluble Flk-1 Inhibits Metastatic and Primary Tumor Growth in Renal Cell Carcinoma

James W. Yockman, Won Jong Kim, Chien-Wen Chang and Sung Wan Kim

Mol Ther 13: S101-S101; doi:10.1016/j.ymthe.2006.08.319

266. Gene Modification of T Antigen Presenting Cells for the Induction of Antitumor Immunity

Aaron E. Foster, Ann M. Leen, Timothy Lee, Juan Vera, Gianpietro Dotti and Cliona M. Rooney

Mol Ther 13: S101-S102; doi:10.1016/j.ymthe.2006.08.320

267. Synergistic Antitumor Effect of neu DNA Vaccine and Low Dose of Geldanamycin

Chi-Chen Lin, Meng-Chi Yen and Ming-Derg Lai

Mol Ther 13: S102-S102; doi:10.1016/j.ymthe.2006.08.321

268. CD19-Targeted Normal and CLL Patient T Cells Expanded with Beads Can Eradicate Systemic Tumors In Vivo

J. Stefanski, R. Brentjens, D. Hollyman, M. Bonyhadi, M. Sadelain and I. Rivi|[egrave]|re

Mol Ther 13: S102-S102; doi:10.1016/j.ymthe.2006.08.322

269. Integrated CD28 and 4-1BB Signals Strongly Potentiate CD8+ T Cell Mediated radication of Metastatic Prostate Cancer

Xiao-Song Zhong, Maiko Matsushita, Aurore Saudemont, Elmer Santos and Michel Sadelain

Mol Ther 13: S103-S103; doi:10.1016/j.ymthe.2006.08.323

270. The RheoSwitch|[reg]| Therapeutic System Precisely Regulates IL-2 Expression in Melanoma Cells and Supports Survival of NK Cells at the Tumor Site

Anand K. Katakam, Qin Yang, Steve Goding, Prasanna Kumar and Per H. Basse

Mol Ther 13: S103-S103; doi:10.1016/j.ymthe.2006.08.324

271. Full-Length Antibody Therapy Mediated by Adenovirus in Rodent and Non-Primate Animal Models

Wenfang Shi, Jie Chen, Minghong Jiang, Changqing Su and Qijun Qian

Mol Ther 13: S104-S104; doi:10.1016/j.ymthe.2006.08.325

272. Conversion of a Tumor-Binding Peptide Identified by Phage Display to a Functional Chimeric T-Cell Antigen Receptor

Colette R.J. Pameijer, Araceli Hamlett, Bessie Meechovet, Jamie Buckmaster, Brenda Aguilar, Christine Wright, Wen- Chung Chang, Christine E. Brown and Michael C. Jensen

Mol Ther 13: S104-S104; doi:10.1016/j.ymthe.2006.08.326

273. Immuno Gene Therapy of Feline Fibrosarcoma Using Intratumoral Magnetofection or Gene-Activated Matrices for Gene Delivery |[ndash]| Preliminary Results of a Veterinary Clinical Study

Ulrike Schillinger, Bianca Schwarz, Tina Kempf, Anika Jahnke, Cornelia Fischer, Anne Loecher, Stefanie Schlemmer, Johannes Hirschberger, Thomas Brill, Roberto Koestlin, Bernd Gaensbacher and Christian Plank

Mol Ther 13: S105-S105; doi:10.1016/j.ymthe.2006.08.327

274. Antitumor Effect of Controlled Expression of Interleukin-12 in a Murine Model of Liver Metastases

Itsaso Mauleon, Julien Crettaz, Gloria Gonzalez-Aseguinolaza, Maider Zabala, Gabriela Kramer, Stephan Kochanek, Jesus Prieto and Ruben Hernandez-Alcoceba

Mol Ther 13: S105-S105; doi:10.1016/j.ymthe.2006.08.328

275. Immunostimulatory Antigen Loaded Microparticles as Cancer Vaccines

Aliasger K. Salem, Anthony D. Sandler, George J. Weiner, Xueqing Zhang, Nicki K. Baman, Xiaoyan Zhu and Christopher E. Dahle

Mol Ther 13: S105-S105; doi:10.1016/j.ymthe.2006.08.329

276. Phase I Trial of Sequential Administration of Recombinant DNA and Adenovirus Expressing L523S Protein in Early Stage Non Small Cell Lung Cancer (NSCLC)

John Nemunaitis, Thomas Meyers, Neil Senzer, Casey Cunningham, Howard West, Eric Vallieresma, Stephen Anthony, Svetislava Vukelja, Barry Berman, Heather Tully, Beena Pappen, Stephen Sarmiento, Rosemarie Arzaga, Steven Duniho, Susan Engardt, Madeleine Meagher and Martin Cheever

Mol Ther 13: S106-S106; doi:10.1016/j.ymthe.2006.08.330

277. Clinical Evaluation of Dendritic Cell Vaccination for Patients with Recurrent Glioma: Results of a Clinical Phase I/II Trial

Ryuya Yamanaka, Junpei Homma, Naoki Yajima, Masakazu Sano and Masuhiro Takahashi

Mol Ther 13: S106-S106; doi:10.1016/j.ymthe.2006.08.331

278. Therapeutic Activities of IL-12 Gene- Modified Macrophages Embedded in Gelatin Matrix Hemostatic Sealant (FloSeal|[reg]|) in a Mouse Model of Residual Prostate Cancer

Ken-ichi Tabata, Masami Watanabe, Takefumi Satoh, Wei-hau Tian, Hongyu Wang, ElMoataz Abdel Fattah, Guang Yang, Daniel Floryk, Dov Kadmon and Timothy C. Thompson

Mol Ther 13: S106-S106; doi:10.1016/j.ymthe.2006.08.332

279. Eradication of Renal Cell Carcinoma in Mice Mediated by NK Cell Activation Using Inactivated Sendai Virus Particle (HVJ-E)

Atsuko Fujihara, Masayuki Kurooka, Tsuneharu Miki and Yasufumi Kaneda

Mol Ther 13: S107-S107; doi:10.1016/j.ymthe.2006.08.333

280. RANTES and TARC Enhanced the Antitumor Immune Effects of GM-CSF

Hiroyuki Inoue, Takafumi Nakamura, Meng Xin, Yoshito Beppu, Gaku Sakaguchi, Ryo Kurita, Hidenori Hase, Yukoh Nakazaki, Yoshikazu Yonemitsu, Koichi Takayama, Yoichi Nakanishi, Yusuke Nakamura, Shigetaka Asano and Kenzaburo Tani

Mol Ther 13: S107-S107; doi:10.1016/j.ymthe.2006.08.334

281. Adenovirus-Mediated CD40 Ligand Therapy Induces Tumor Cell Apoptosis and Systemic Immunity in the TRAMP-C2 Mouse Prostate Cancer Model

Helena Dzojic, Angelica Loskog, Thomas Totterman and Magnus Essand

Mol Ther 13: S107-S107; doi:10.1016/j.ymthe.2006.08.335

282. Antitumor Efficacy of Intravenous Administration of Oncolytic Herpes Simplex Virus Expressing Interleukin 12

Yi Guan, Yasushi Ino, Hiroshi Fukuhara and Tomoki Todo

Mol Ther 13: S108-S108; doi:10.1016/j.ymthe.2006.08.336

283. DNA Vaccination with Genes Encoding an Antigenic Protein and Fas Ligand Increased Antigen-Specific Humoral Responses

Osamu Shimozato, Ayako Sato, Kiyoko Kawamura, Quanhai Li, Guangyu Ma and Masatoshi Tagawa

Mol Ther 13: S108-S108; doi:10.1016/j.ymthe.2006.08.337

284. Reduced Lung Metastasis of Secreted Type of Substance P Gene Modified Mouse Melanoma Cells

Xianghui He, Zhixiang Zhang, Liwei Zhu, Tom C. Tsang and David T. Harris

Mol Ther 13: S108-S108; doi:10.1016/j.ymthe.2006.08.338

285. Concanavalin A That Bears Direct Cytotoxicity and Immunomodulating Activity Via Mannose-Specific Cellular Binding Has Therapeutic Effect in a Murine In Situ Hepatoma Model

Chih-Peng Chang, Ying-Tai Jin and Huan-Yao Lei

Mol Ther 13: S109-S109; doi:10.1016/j.ymthe.2006.08.339

286. Biodistribution and Cearance Following Intraperitoneal Injection of Murine Interleukin-12 Plasmid Formulated with a Novel Polymeric Delivery System

Elaine Brunhoeber, Majed Matar, Khursheed Anwer and Jason G. Fewell

Mol Ther 13: S109-S109; doi:10.1016/j.ymthe.2006.08.340

287. Safety and Toxicity Following Intraperitoneal Injection of Murine Interleukin-12 Plasmid Formulated with a Novel Polymeric Delivery System

Jason G. Fewell, Jennifer Rice, Majed Matar and Khursheed Anwer

Mol Ther 13: S109-S109; doi:10.1016/j.ymthe.2006.08.341

288. Bi-Modality Induction of TNF|[alpha]|: Neoadjuvant Chemoradiotherapy and TNFerade|[trade]| in Patients with Locally Advanced, Resectable Esophageal Carcinoma

Neil Senzer, Kenneth Chang, Stephen Swisher, Tony Reid, Ann Mauer, Amitabh Chak, Harlan Pinto and John Nemunaitis

Mol Ther 13: S110-S110; doi:10.1016/j.ymthe.2006.08.343

289. Adenoviral-Mediated p53 Gene Therapy (Advexin) in a Patient with Li-Fraumeni Syndrome with a Mixed Germ Cell Tumor: Tolerability and Response

Neil Senzer, Jeffrey Lamont and John Nemunaitis

Mol Ther 13: S110-S110; doi:10.1016/j.ymthe.2006.08.344

290. Prolegomenon to a Phase II Study of an ICP34.5/ICP47 Deleted Herpes Simplex Virus Containing the Coding Sequence for GM-CSF in Patients with Melanoma

Neil Senzer and John Nemunaitis

Mol Ther 13: S110-S110; doi:10.1016/j.ymthe.2006.08.345

291. In Vivo Characterization of Seneca Valley Virus (SVV-001), a Novel Oncolytic Picornavirus for Systemic Treatment of Patients with Solid Tumors with Neuroendocrine Features

Kevin D. Burroughs, Kristine Skele, Christian Sherk, Brian Jones, Ann-Jeanette Vasko, Laura Hales, Seshidhar R. Police and Paul L. Hallenbeck

Mol Ther 13: S111-S111; doi:10.1016/j.ymthe.2006.08.346

292. Polyethylenimine Mediated Oral Cancer Targeted PUMA Gene Delivery Suppressed Tumor Growth and Prolonged Survival

Benson Chen, Ming-Shyan Huang, Steven Yeh, Mark Y.P. Kuo and Michael Hsiao

Mol Ther 13: S111-S111; doi:10.1016/j.ymthe.2006.08.347

293. Sustained Expression of Kringle 1 Domain of Human Hepatocyte Growth Factor (HGFK1) Effectively Inhibits Angiogenesis, Growth and Metastasis of Hepatocellular Carcinoma

Zan Shen, Zhen Fan Yang, Yi Gao, Ching Chiu Liu, Samuel S. Ng, Sheung Tat Fan, Ming-liang He, Tsai-ping Li, Ren-bao Gan, Hsiang-fu Kung and Marie Chia-mi Lin

Mol Ther 13: S111-S112; doi:10.1016/j.ymthe.2006.08.348

294. The Histone Deacetylase Inhibitor FK228 Increases Histone Acetylation, Coxsackie Adenovirus Receptor Levels and Adenovirus Transgene Expression in Human LOX IMVI Melanoma Xenografts

Merrill E. Goldsmith, Kenneth Steadman, Alian Aguila, Michael C. Alley, William R. Waud, Susan Bates and Tito Fojo

Mol Ther 13: S112-S112; doi:10.1016/j.ymthe.2006.08.349

295. Effects of Sustained Anti-Angiogenic Gene Therapy in Multi-Stage Prostate Cancer in TRAMP Mice

Tatyana Isayeva, Diptiman Chanda and Selvarangan Ponnazhagan

Mol Ther 13: S112-S112; doi:10.1016/j.ymthe.2006.08.350

296. Transgene Expression and Neutralizing Antibody Production after Submandibular Gland Administration of AdhAQP1

Corinne M. Goldsmith, Changyu Zheng, Molly Vallant, Richard D. Irwin and Bruce J. Baum

Mol Ther 13: S113-S113; doi:10.1016/j.ymthe.2006.08.351

297. Safety of Repeat Intracerebral Administration of MV-CEA in Rhesus Macaques in Support of a Phase I/II Clinical Trial for Patients with Recurrent Gliomas

Rae M. Myers, Mary E. Harvey, Suzanne M. Greiner, Diane C. Soeffker, James W. Krempski, Paula J. Zollman, Steven E. Shelton, Raffel Corey, Goerss J. Stephan, Kaufmann J. Timothy, Federspiel J. Mark, Peng Kah-Whye, Russell J. Stephen and Galanis Evanthia

Mol Ther 13: S113-S113; doi:10.1016/j.ymthe.2006.08.352

298. Combination Effect of Telomerase-Specific Replication-Competent Adenovirus (Telomelysin, OBP-301) and p53 Gene Therapy in Human Non- Small Cell Lung and Colon Cancer Cells

Ryo Sakai, Fuminori Teraishi, Toru Kojima, Yoshihiro Ikeda, Masayoshi Hioki, Toshiya Fujiwara, Futoshi Uno, Shunsuke Kagawa, Yuuri Hashimoto, Yuichi Watanabe, Yasuo Urata, Noriaki Tanaka and Toshiyoshi Fujiwara

Mol Ther 13: S114-S114; doi:10.1016/j.ymthe.2006.08.353

299. In Vivo Luciferase Imaging for Analysis of Oncolytic Adenoviruses for Renal Cell Cancer

Kilian Guse, Tuuli Ranki, Tanja Hakkarainen, Martti Ala- Opas, Tommi Pisto, Merja S|[auml]|rkioja, Maria Rajecki, Anna Kanerva and Akseli Hemminki

Mol Ther 13: S114-S114; doi:10.1016/j.ymthe.2006.08.354

300. Gene Therapy for Gastric Cancer Cells Via CEA-Targeted Adv-FZ33

Toshihiro Tanaka, Jianhua Huang, Sachie Hirai, Motomu Kuroki, Masahide Kuroki, Naoki Watanabe, Kazunori Kato and Hirofumi Hamada

Mol Ther 13: S114-S115; doi:10.1016/j.ymthe.2006.08.355

301. Safe and Effective Treatment of Ovarian Cancer Models Using Targeted Adenovirus Vector Delivery and Selective Expression of Tumor Necrosis Factor

Selva R. Murugesan, Masaki Akiyama, David A. Einfeld, Thomas J. Wickham and C. Richter King

Mol Ther 13: S115-S115; doi:10.1016/j.ymthe.2006.08.356

302. Anti-Angiogenic Treatment Enhances Anti- Tumor Effects of an Oncolytic Virus in an Experimental Rat Glioma Model

Kazuhiko Kurozumi, Jennifer Cutter, William Carson, Ming Yang, Gregory Christoforidis, Antonio E. Chiocca and Balveen Kaur

Mol Ther 13: S115-S116; doi:10.1016/j.ymthe.2006.08.357

303. Enhanced Antitumor Efficacy of Telomerase-Selective Oncolytic Adenoviral Agent OBP-401 with Docetaxel: Preclinical Evaluation of Chemovirotherapy

Yoshihiro Ikeda, Toshiya Fujiwara, Shunsuke Kagawa, Masayoshi Hioki, Ryo Sakai, Toru Kojima, Yasuo Urata, Noriaki Tanaka and Toshiyoshi Fujiwara

Mol Ther 13: S116-S116; doi:10.1016/j.ymthe.2006.08.358

304. Therapeutic Efficacy of a Mesothelin Promoter-Based Conditionally Replicative Adenovirus Monitored by In Vivo Imaging of an Ovarian Cancer Model

Yuko Tsuruta, Larisa Pereboeva, Martina Breidenbach, Daniel T. Rein, Masaharu Nakayama, Gene P. Siegal and David T. Curiel

Mol Ther 13: S116-S116; doi:10.1016/j.ymthe.2006.08.359

305. Targeting the Gene and the Derived Gene- Product into Tumors

Shulin Li, Ryan Craig and Marina Torrero

Mol Ther 13: S117-S117; doi:10.1016/j.ymthe.2006.08.360

306. Imaging HSV-1 Viral Oncolysis of Colon Cancer Cells by microPET

Darshini Kuruppu, Aijun Zhu, Meixiang Yu, Anna-Liisa Brownell and Kenneth K. Tanabe

Mol Ther 13: S117-S117; doi:10.1016/j.ymthe.2006.08.361

307. Prostate Targeted TSTA Oncolytic Adenovirus

Makoto Sato, Steve Huyn, Russell Powell, Michael Carey, Sanjiv S. Gambhir and Lily Wu

Mol Ther 13: S117-S118; doi:10.1016/j.ymthe.2006.08.362

308. Valproic Acid, a Histone Deacetylase Inhibitor, Is an Antagonist for Oncolytic Adenoviral Gene Therapy

Naser Uddin Hoti, Shawn E. Lupold, Wasim Chowdhury, Jer-Tsong Hsieh and Ronald Rodriguez

Mol Ther 13: S118-S118; doi:10.1016/j.ymthe.2006.08.363

309. Oncolytic Efficacy and Enhanced Safety of Measles Virus Activated by Tumor-Secreted Matrix-Metalloproteases

Christoph Springfeld, Veronika von Messling, Marie Frenzke, Guy Ungerechts, Christian Buchholz and Roberto Cattaneo

Mol Ther 13: S118-S118; doi:10.1016/j.ymthe.2006.08.364

310. Antitumor Effect of Telomerase-Specific Virotherapy in Pleural Dissemination of Human Malignant Mesothelioma

Yuichi Watanabe, Yuuri Hashimoto, Toru Kojima, Shunsuke Kagawa, Hitoshi Kawamura, Katsuyuki Nagai, Noriaki Tanaka, Yasuo Urata and Toshiyoshi Fujiwara

Mol Ther 13: S118-S118; doi:10.1016/j.ymthe.2006.08.365

311. Target-Specific Knockdown and Enhanced Anti-Tumor Outcome by an Oncolytic Virus- Delivered Small Interfering RNA (siRNA)

Alex W. Tong, Yu-An Zhang, Shirley Samuel, Patrick Chen, Yuqiao Shen and John Nemunaitis

Mol Ther 13: S118-S119; doi:10.1016/j.ymthe.2006.08.366

312. Clearance of Helper Adenovirus by an AAV1 Clinical Vector Manufacturing Process

Barb Thorne, Paulene Quigley, Gina Nichols, David Price, Christine Moore, Kristin Parker, Tsering Sangmo, Eric Pastor, Morgan Peterson, Ryan Takeya and Richard Peluso

Mol Ther 13: S119-S119; doi:10.1016/j.ymthe.2006.08.368

313. Cell Type Specific Media Optimization for Clinical Retroviral Transduction Protocols

J. Stefanski, O. Borquez-Ojeda, T. Budak-Alpdogan, R. Kendle, M. Przybylowski, D. Hollyman, M. Sadelain and I. Rivi|[egrave]|re

Mol Ther 13: S119-S120; doi:10.1016/j.ymthe.2006.08.369

314. Developing Gene Transfer Vectors for Cancer Therapy: Identifying and Overcoming Regulatory Challenges

Rosemarie Aurigemma

Mol Ther 13: S120-S120; doi:10.1016/j.ymthe.2006.08.370

315. Identification and Control of Bacterial Contamination in an Academic Good Manufacturing Practice Facility

Timothy P. O'Connor, Neil R. Hackett, Robert G. Pergolizzi, Dolan Sondhi, Julie L. Boyer, Stephen M. Kaminsky and Ronald G. Crystal

Mol Ther 13: S120-S120; doi:10.1016/j.ymthe.2006.08.371

316. Production of Adenoviral Vectors in an Academic cGMP Facility

M.F. Medina, J. Rudy, U. Sankar, D. Chong, R. Foley and J. Gauldie

Mol Ther 13: S121-S121; doi:10.1016/j.ymthe.2006.08.372

317. Simplified Concentration and Purification of Lentivirus Pseudotypes

Robert H. Kutner, Brian DaLeo and Jakob Reiser

Mol Ther 13: S121-S121; doi:10.1016/j.ymthe.2006.08.373

318. Collaborative Development of an Effective Method To Produce Clinical RNAi Products

Sriram Ramakrishnan, Jeffrey E. Darnell, Gary Gates, Hugo L. Gonzales, Justin Miller and Henry Hebel

Mol Ther 13: S121-S121; doi:10.1016/j.ymthe.2006.08.374

319. Comparison of Serum-Free Media for Optimal Ex Vivo Transduction of Human CD34+ Cells

Joanna L. Ireland, Greg M. Podsakoff, Donald B. Kohn and Barbara C. Engel

Mol Ther 13: S122-S122; doi:10.1016/j.ymthe.2006.08.375

320. Modeling Human Brain Cancer in Transgenic E2F1 Mice

Melissa V. Olson, Kenneth D. Aldape, Gregory N. Fuller, Marta M. Alonso, Candelaria Gomez-Manzano, Johnson G. David and Fueyo Juan

Mol Ther 13: S122-S122; doi:10.1016/j.ymthe.2006.08.377

321. Sea Urchin sns Chromatin Insulator Prevents Silencing and Positional Effect Variegation of Oncoretroviral Vectors Transgene Expression in Murine Erythroid Cell Line

Danilo D'Apolito, Santina Acuto, Rosalba Di Marzo, Mariella Bagliesi, Valentina Motta, Elena Baiamonte, Roberta Calzolari, Vito Franco, Giovanni Spinelli and Aurelio Maggio

Mol Ther 13: S122-S123; doi:10.1016/j.ymthe.2006.08.378

322. Syngeneic Cotton Rat Cancer Model for Replicating Adenoviral Vectors

Jason C. Steel, Brian J. Morrison, Poonam Mannan, Gregory A. Prince, Kevin C. Yim, Brian K. Miles, Oliver Wildner and John C. Morris

Mol Ther 13: S123-S123; doi:10.1016/j.ymthe.2006.08.379

323. In Vivo Regulation of rAAV-Mediated GDNF Expression in the Rat Striatum

Corinna Burger, Emily Piercefield, Layla Sullivan, Ronald Mandel and Nicholas Muyczka

Mol Ther 13: S123-S123; doi:10.1016/j.ymthe.2006.08.380

324. Development of Bioluminescence Tomography for Three-Dimensional Real Time Imaging of Gene Expression

Nathalie Y. Toussaint, Lu Yin, Aaron Hirko, Qiang Wang, Qizhi Zhang, Huabei Jiang and Sean Sullivan

Mol Ther 13: S123-S124; doi:10.1016/j.ymthe.2006.08.381

325. In Vitro Gene Knockdown of Rat Pyruvate Dehydrogenase E1 |[alpha]| mRNA by Self- Complementary Adeno-Associated Virus-Mediated Small Interfering RNA Delivery

Zongchao Han, Marina Gorbatyuk, Alfred Lewin, Arun Srivastava and Peter Stacpoole

Mol Ther 13: S124-S124; doi:10.1016/j.ymthe.2006.08.382

326. A Versatile Tool for Conditional Gene Expression and Knockdown

Jolanta Szulc, Maciej Wiznerowicz, Friedrich Beermann, Didier Trono and Patrick Aebischer

Mol Ther 13: S124-S124; doi:10.1016/j.ymthe.2006.08.383

327. Muscle Specific and Efficient Transgene Expression Using the Fast and Slow Troponin I Promoters in Cell Culture

Marilyne Blain, Angela Kumar, Kenneth E. Hastings, George Karpati, Bernard Massie and Renald Gilbert

Mol Ther 13: S125-S125; doi:10.1016/j.ymthe.2006.08.384

328. Transcriptionally Targeted Cancer Gene Therapy for Small Cell Lung Cancer

Nina Pedersen, Thomas T. Poulsen, Mikkel W. Pedersen, Michael S. Lan, Mary B. Breslin and Hans S. Poulsen

Mol Ther 13: S125-S125; doi:10.1016/j.ymthe.2006.08.385

329. Electroporation-Mediated Delivery of Cre- Expressing Plasmids to the Lung Results in Tissue-Specific DNA Excision in Transgenic Mice

Aaron M. Miller and David A. Dean

Mol Ther 13: S125-S126; doi:10.1016/j.ymthe.2006.08.386

330. Effect of Different Inducible Minimal Promoters in the RheoSwitch|[reg]| Therapeutic System That Give Robust and Long-Term In Vivo Gene Expression

Jessica L. Seitzer, Anand Katakam, Marti A. DiPietro, Prasanna Kumar and David W. Potter

Mol Ther 13: S126-S126; doi:10.1016/j.ymthe.2006.08.387

331. Small Fragment Homologous Replacement (SFHR) Modification of Genomic HPRT Occurs in the Presence of Wild-Type p53 in Lymphoblastoid Cells

Babak Bedayat, Alireza Abdolmohammadi, Rosalie Maurisse, Jennifer Shwarz, Judi Cheung, David De Semir, Patric K O'Neill, Janice A. Nicklas and Dieter C. Gruenert

Mol Ther 13: S126-S126; doi:10.1016/j.ymthe.2006.08.388

332. Routes of Ligand Administration That Give Efficient and Robust In Vivo Induction with the RheoSwitch|[reg]| Therapeutic System

Marti A. DiPietro, Jessica L. Seitzer and David W. Potter

Mol Ther 13: S126-S127; doi:10.1016/j.ymthe.2006.08.389

333. Focused Ultrasound-Induced Transgene Activation in Skeletal Muscles

Xiaochun Lu, Georgii Sankin, John Madden and Pei Zhong

Mol Ther 13: S127-S127; doi:10.1016/j.ymthe.2006.08.390

334. A Novel Sequence-Specific Anti-Gene LNA Molecule and Its Comparison to Tail-Clamp bisPNA

Rongbin Ge, Juhana E. Heinonen, Mathias G. Svahn, Abdalla J. Mohamed, Karin E. Lundin and C.I. Edvard Smith

Mol Ther 13: S127-S127; doi:10.1016/j.ymthe.2006.08.391

335. Global Transcriptional Profiles of Murine C2C12 Myoblasts Treated with IGF-1

C. Ramana Bhasker, Shaochun Song and Theodore Friedmann

Mol Ther 13: S127-S127; doi:10.1016/j.ymthe.2006.08.392

336. Impact of Convective Flow on the Cellular Uptake and Transfection Activity of Lipoplex and Adenovirus

Takahiro Fujiwara, Hidetaka Akita, Katsuko Furukawa, Takashi Ushida and Hideyoshi Harashima

Mol Ther 13: S128-S128; doi:10.1016/j.ymthe.2006.08.393

337. Adenoviral Delivery of the RheoSwitch|[reg]| Therapeutic System to Mouse Brain and Liver

David W. Potter, Marti A. DiPietro, Jessica L. Seitzer, Anand Katakam and Prasanna Kumar

Mol Ther 13: S128-S128; doi:10.1016/j.ymthe.2006.08.394

338. Microarray Analysis of Genes Regulated during Induction of Osteogenesis by Human Lim Mineralization Protein-3 (LMP-3) in Human Mesenchymal Stem Cells

Wanda Lattanzi, Camilla Bernardini, Enrico Pola, Andrea Gambotto, Fabrizio Michetti and Paul D. Robbins

Mol Ther 13: S128-S129; doi:10.1016/j.ymthe.2006.08.395

339. FIV Lentiviral Vector Gene Transfer for Hemophilia A

C.P. Chikkanna-Gowda, Litao Xie, Yubin Kang, Melissa A. Hickey, Patrick L. Sinn, Jessica D. Goreham-Voss, Steven W. Pipe and Paul B. McCray Jr.

Mol Ther 13: S129-S129; doi:10.1016/j.ymthe.2006.08.396

340. Cellular Uptake and Subsequent Intracellular of R8-Liposomes Introduced at Low Temperature

Akitada Iwasa, Hidetaka Akita, Ikramy Khalil, Kentaro Kogure, Shiroh Futaki and Hideyoshi Harashima

Mol Ther 13: S129-S129; doi:10.1016/j.ymthe.2006.08.397

341. Lentivirus Transduction of Murine Embryonic Stem Cells with Truncated Human Low-Affinity Nerve Growth Factor Permits Efficient Purification of Genetically Modified Cells without Loss of Stem Cell Characteristics

Ralf-Harto H|[uuml]|bner, Maija Kiuru, Anja Krause, Stefano Rivella, Robert G. Pergolizzi and Ronald G. Crystal

Mol Ther 13: S130-S130; doi:10.1016/j.ymthe.2006.08.399

342. RUNX1 Increases Proliferation of Embryoid Bodies Derived from Human Embryonic Stem Cells

Jenice D'Costa, Alan D. Friedman, Elias Zambidis and Curt I. Civin

Mol Ther 13: S130-S130; doi:10.1016/j.ymthe.2006.08.400

343. Vascular Endothelial Growth Factor Prevents Bone Marrow Derived-Mesenchymal Stem Cell Senescence In Vitro

Jennifer Pons, Hua Su, Yu Huang and Y.W. Kan

Mol Ther 13: S131-S131; doi:10.1016/j.ymthe.2006.08.401

344. AAV Vector-Mediated Msx1 Gene Transfer Induces Hematopoietic Stem/Progenitor Cells in Skeletal Muscle

Masaharu Nobuyoshi, Akihiro Kume, Takashi Matsushita, Hiroaki Mizukami, Takashi Okada, Masashi Urabe, Yuichi Ohgoshi, Takashi Endo and Keiya Ozawa

Mol Ther 13: S131-S131; doi:10.1016/j.ymthe.2006.08.402

345. Hematopoietic Stem-Progenitor Cells Express CD52 mRNA and Membrane Protein

Sebastien Morisot, Robert W. Georgantas III and Curt I. Civin

Mol Ther 13: S131-S132; doi:10.1016/j.ymthe.2006.08.403

346. The ACE System, a Mammalian Artificial Chromosome Engineering Technology: Delivery and Transgene Expression in Human Adult & Embryonic Stem Cells

Sandra L. Vanderbyl, Brent Sullenbarger, Neil MacDonald, Melanie Golembiewski, Carl F. Perez, Harry C. Ledebur Jr and Larry C. Lasky

Mol Ther 13: S132-S132; doi:10.1016/j.ymthe.2006.08.404

347. Expression of the N-Formyl Peptide Receptor in Bone Marrow-Derived Human Mesenchymal Stem Cells

Anand Viswanathan, Richard G. Painter, Nicholas A. Lanson Jr and Guoshun Wang

Mol Ther 13: S132-S132; doi:10.1016/j.ymthe.2006.08.405

348. Kruppel-Like Factor 4 Regulates Proliferation of Human and Mouse Hematopoietic Stem-Progenitor Cells, but Is Not Essential for Mouse Hematopoietic Repopulation

Jonathan K. Alder, Robert W. Georgantas, Richard L. Hildreth and Curt I. Civin

Mol Ther 13: S132-S133; doi:10.1016/j.ymthe.2006.08.406

349. Pretreatment of the Esophagus with Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Complex Increases Migration and Proliferation of Marrow Stem Cell Progenitors of Esophageal Squamous Epithelium

Yunyun Niu, Michael W. Epperly and Joel S. Greenberger

Mol Ther 13: S133-S133; doi:10.1016/j.ymthe.2006.08.407

350. Ectopic Retroviral Expression of LMO2, but Not IL2R|[gamma]|, Blocks Human T-Cell Development from CD34+ Progenitor Cells: Implications for Gene Therapy

Karin Pike-Overzet, Dick de Ridder, Floor Weerkamp, Miranda R.M. Baert, Monique M. Verstegen, Steven J. Howe, Adrian J. Thrasher, Gerard Wagemaker, Jacques J.M. van Dongen and Frank J.T. Staal

Mol Ther 13: S133-S133; doi:10.1016/j.ymthe.2006.08.408

351. Inhibition of Thyroid Hormone Receptors in the Neural Stem Cells of Newborn and Adult Mice In Vivo: Consequences on Target Gene Expression

Zahra Hassani, Gladys Alfama, Jean-Christophe Fran|[ccedil]|ois, Carinne Giovannangeli and Barbara A. Demeneix

Mol Ther 13: S134-S134; doi:10.1016/j.ymthe.2006.08.409

352. CD34+ Hematopoietic Stem-Progenitor Cell MicroRNA Expression and Function: The miR Circuit Diagram of Differentiation Control

Robert W. Georgantas, Richard L. Hildreth, John Alder, Carlo Croece, George A. Calin and Curt I. Civin

Mol Ther 13: S134-S134; doi:10.1016/j.ymthe.2006.08.410

353. Biological Comparison of Mesenchymal Stem Cells Derived from Bone Marrow and Adipose Tissue

Reza Izadpanah, Cynthia Trygg, Christopher Kriedt and Bruce Bunnell

Mol Ther 13: S134-S135; doi:10.1016/j.ymthe.2006.08.411

354. Genetic Modification of Murine Stromal- Derived Cells (MSC) in Suspension Culture as a Model for the Rapid Generation of Transplantable Cytoreagents

Yung-Wei Pan, Tammy Tien Luoh and Peter Kurre

Mol Ther 13: S135-S135; doi:10.1016/j.ymthe.2006.08.412

355. A Platform for Gene Delivery to Embryonic Stem Cells Using HSV

April M. Sunyog, Darren Wolfe, James Wechuck, David Krisky, Ying Jiang and Joseph Glorioso

Mol Ther 13: S135-S135; doi:10.1016/j.ymthe.2006.08.413

356. Engineering of Cell Surface Sialic Acids for Polymeric Gene Delivery

Yihua Loo, S.-Gopalan Sampathkumar, Prabhani U. Atukorale, Kevin J. Yarema and Kam W. Leong

Mol Ther 13: S135-S136; doi:10.1016/j.ymthe.2006.08.414

357. Site-Specific Integration of Immortalization Genes in Human Adult Stem Cells Mediated by DirectIt|[trade]| Recombinases

Anna Tretiakova and Malla Padidam

Mol Ther 13: S136-S136; doi:10.1016/j.ymthe.2006.08.415

358. Lentiviral Vector Integration in Mouse Bone Marrow Stem Cells Undergoing Gene Therapy

Xiaolin Wu, Weijing He, Shawn M. Burgess, Robert A. Clark and Senlin Li

Mol Ther 13: S136-S136; doi:10.1016/j.ymthe.2006.08.416

359. Production of Megakaryocytes and Platelets from Common Marmoset (Callithrix jacchus) ES Cells by Constitutive Expression of tal1/scl Gene

Tomoko Yokoo, Ryo Kurita, Erika Sasaki, Kashiya Takasugi, Hideyuki Imoto, Yoshikuni Tanioka, Yasushi Soda and Kenzaburo Tani

Mol Ther 13: S137-S137; doi:10.1016/j.ymthe.2006.08.417

360. Transmitochondrial Stem Cells: Toward Autologous Cybrid Stem Cell Therapy and Synergistic Transient Regenerative Gene Therapy for Mitochondrial (mt)DNA Diseases

Roger Bertolotti

Mol Ther 13: S137-S137; doi:10.1016/j.ymthe.2006.08.418

361. Lentiviral Vector Transduction Efficiency and Biosafety Profile of Adult Mesenchymal Stem Cells

Barry M. McGrath, Ciara O'Shea, Linda Howard, Mary Murphy, Frank Barry, Timothy O'Brien and Padraig M. Strappe

Mol Ther 13: S137-S138; doi:10.1016/j.ymthe.2006.08.419

Top

Abstracts

362. Evaluation the Effects of MIP-1a on Ex Vivo Expansion of Cord Blood Hematopoietic Progenitor Cells in Different Culture Media

Kamran Alimoghaddam, Mitra Khalili, Massoud Soleimani, Moezi Lili, Panthea Ghodsi, Alireza Arjmand and Ardeshir Ghavamzadeh

Mol Ther 13: S138-S138; doi:10.1016/j.ymthe.2006.08.420

363. Homing of Bone Marrow Cells to the Respiratory Epithelium in a Murine Acute Infection Model

Joanna Rejman and Massimo Conese

Mol Ther 13: S138-S138; doi:10.1016/j.ymthe.2006.08.421

364. The Effect of Overexpression of Vascular Endothelial Growth Factor in Mouse Embryonic Stem Cells on Angiogenesis

Ying Ka Lau and Jennifer L. West

Mol Ther 13: S138-S139; doi:10.1016/j.ymthe.2006.08.422

365. Human Embryonic Stem Cells: Genetic Conversion to the Fanconi Anemia Phenotype

Beiqing Pan and Christopher E. Walsh

Mol Ther 13: S139-S139; doi:10.1016/j.ymthe.2006.08.423

366. Suicide Gene Therapy of Glioma Using Genetically Engineered Human Mesenchymal Stem Cells

Hiroki Namba, Shaoyi Li, Tsutomu Tokuyama, Junkoh Yamamoto and Naoki Yokota

Mol Ther 13: S139-S139; doi:10.1016/j.ymthe.2006.08.424

367. Lentivirus Pseudotyped with Envelope Proteins F and HN from Sendai Virus Transduce Airway Epithelium Efficiency and Persistently

Uta Griesenbach, Katsuyuki Mitomo, Makoto Inoue, Lucinda Somerton, Raymond Farley, Charanjit Singh, Toshiaki Tabata, Yasuji Ueda, Satoshi Fujikawa, Kentaro Washizawa, Mamoru Hasegawa and Eric W.F.W. Alton

Mol Ther 13: S139-S140; doi:10.1016/j.ymthe.2006.08.426

368. Lentiviral Vector Strain of Origin and Target Cell Species-Specific Restriction Factors Influence Transduction Efficiency

Christoph A. Kahl, Paula M. Cannon, Jill Oldenburg and Donald B. Kohn

Mol Ther 13: S140-S140; doi:10.1016/j.ymthe.2006.08.427

369. Development of an Amplifiable Gene Expression System in Lentivirus Vectors

Kit L. Shaw, Karen Pepper, Denise Petersen, Shundi Ge, Gay Crooks and Donald B. Kohn

Mol Ther 13: S140-S140; doi:10.1016/j.ymthe.2006.08.428

370. CRM1 Enhances the Lentiviral Vector Production

Hsin-Lung Lo, Tammy Chang, Paola M. Marcovecchio, Priscilla Yam, John A. Zaia and Jiing-Kuan Yee

Mol Ther 13: S141-S141; doi:10.1016/j.ymthe.2006.08.429

371. Optimization of Feline Immunodeficiency Viral Vectors for RNA Interference

Scott Q. Harper, Patrick D. Staber, Christine Rowley, Sarah Fineberg, Dalyz Ochoa, Colleen Stein and Beverly L. Davidson

Mol Ther 13: S141-S141; doi:10.1016/j.ymthe.2006.08.430

372. Optimizing Foamy Virus Vectors That Inhibit HIV Infection

Jason A. Taylor, Lucia Vojtech, Erik M. Olson, James M. Allen, Grant D. Trobridge, David W. Russell and Robert E. Richard

Mol Ther 13: S141-S142; doi:10.1016/j.ymthe.2006.08.431

373. Targeting the Central Nervous System by Intravenous Administration of a Targeting Lentiviral Vector

Koki Morizono, Yiming Xie, Gene-Errol Ringpis, Nonia Pariente and Irvin S.Y. Chen

Mol Ther 13: S142-S142; doi:10.1016/j.ymthe.2006.08.432

374. Hepatitis Delta Virus-Mediated Amplification of Therapeutic RNAi

Dirk Haussecker, Menashe Elazar, Jeff S. Glenn and Mark A. Kay

Mol Ther 13: S142-S142; doi:10.1016/j.ymthe.2006.08.433

375. A Glaucoma Gene Therapy Model: Eighteen Cat Study Revealing Long-Term Targeted Genetic Modification of the Anterior Chamber by Lentiviral Vectors

Pranay D. Khare, Nils Loewen, Roman Barraza, Michael Fautsch, Douglas Johnson and Eric Poeschla

Mol Ther 13: S142-S143; doi:10.1016/j.ymthe.2006.08.434

376. Hepatic Tropism of Adenoviral Type 5 Vectors Can Be Mediated by Multiple Coagulation Factors

Alan L. Parker, Campbell G. Nicol, Simon N. Waddington, Suzanne M. Buckley, Dmitry M. Shayakhmetov, Shaoheng H. Ni, Andre Lieber, John H. McVey, Laura Denby, Stuart A. Nicklin and Andrew H. Baker

Mol Ther 13: S143-S143; doi:10.1016/j.ymthe.2006.08.436

377. Intravascular Delivery of Adenovirus Vectors Rapidly Targets Platelets to the Reticuloendothelial System

Daniel Stone, Shaoheng Ni, Zong-Yi Li, Dmitry Shayakhmetov and Andre Lieber

Mol Ther 13: S143-S144; doi:10.1016/j.ymthe.2006.08.437

378. Phase I Trial of Intravenous Infusion of Onyx 015 and Enbrel in Solid Tumor Patients

Gerald Edelman, Neil Senzer, Michael Nemunaitis, Casey Cunningham, Paige Sovern, Alex Tong and John Nemunaitis

Mol Ther 13: S144-S144; doi:10.1016/j.ymthe.2006.08.438

379. Identification of Structural Aspects of Adenovirus Interactions with Host Factors In Vivo Using Tandem Mass Spectrometry

Oleksandr Kalyuzhniy, Catalin Doneanu, Martin Sadilek and Dmitry M. Shayakhmetov

Mol Ther 13: S144-S144; doi:10.1016/j.ymthe.2006.08.439

380. Alternative Cellular Receptor for B-Group Adenoviruses: Implications for Gene Therapy

Sebastian Tuve, Hongjie Wang, Anuj Gaggar, Ying Liu and Andre Lieber

Mol Ther 13: S145-S145; doi:10.1016/j.ymthe.2006.08.440

381. The Adenoviral Fiber Shaft Is a Major Determinant of Kupffer Cell Necrosis

Jeffrey S. Smith, Jie Tian, Susan C. Stevenson and Andrew P. Byrnes

Mol Ther 13: S145-S145; doi:10.1016/j.ymthe.2006.08.441

382. The Polysaccharide Mannan as a Novel Chemical Coupling Partner for Adenovirus Vectors with a Potential Use for Genetic Vaccination

Sigrid Espenlaub, Andreas Wortmann, Tatjana Dick, Stefan Kochanek and Florian Kreppel

Mol Ther 13: S145-S146; doi:10.1016/j.ymthe.2006.08.442

383. Polyethylene Glycol Modification of Adenovirus Vectors Reduces Thrombocytopenia through Decreased Platelet Clearance and Activation

Hoyin Mok, Francisca C. Gushkin, Sean Hofherr, Jose A. Lopez and Michael A. Barry

Mol Ther 13: S146-S146; doi:10.1016/j.ymthe.2006.08.443

384. Species B Adenovirus and Hematopoietic Cells Revisited

Goeran Wadell, Anna Segerman, William Burmeister, Steven Cusack, Emma Andersson, Karin Edlund, Praveen Papareddy, Dan Gustafsson, Kristina Lindman, Marko Marttila, Johan Skog, Niklas Arnberg and Ya-fang Mei

Mol Ther 13: S146-S146; doi:10.1016/j.ymthe.2006.08.444

385. Tol2 Transposon as a Gene Therapy Vector: Characterization, Optimization and Correction of Hereditary Tyrosinemia Type 1 in Mouse

Darius Balciunas, Andrew Wilber, Kirk Wangensteen, Jason Bell, Aron Geurts, Perry B. Hackett, David A. Largaespada, R. Scott McIvor and Stephen C. Ekker

Mol Ther 13: S147-S147; doi:10.1016/j.ymthe.2006.08.446

386. Chromosomal Integration Sites of Double-Stranded Linear DNA in Mouse ES Cells

Fumi Ohbayashi and Ko Mitani

Mol Ther 13: S147-S147; doi:10.1016/j.ymthe.2006.08.447

387. Advantageous Properties of the piggyBac Transposon System for Gene Transfer in Human Cells

Matthew H. Wilson, Craig J. Coates, Edward J. Rebar and Alfred L. George Jr.

Mol Ther 13: S147-S148; doi:10.1016/j.ymthe.2006.08.448

388. Chromosomal Rearrangements in Mammalian Cells Are Induced at High Frequency by the Bacteriophage Derived Integrase phiC31

Anja Ehrhardt, Jeffrey A. Engler, Hui Xu, Athena Cherry and Mark A. Kay

Mol Ther 13: S148-S148; doi:10.1016/j.ymthe.2006.08.449

389. Directed Transposon Integration in Human Cells

Stephen R. Yant, Yong Huang, Bassel Akache and Mark A. Kay

Mol Ther 13: S148-S149; doi:10.1016/j.ymthe.2006.08.450

390. Phage c31 Integrase Induces Chromosomal Aberrations in Primary Human Fibroblasts

Jian Liu, Iben Jeppesen, Kate Nielsen and Thomas G. Jensen

Mol Ther 13: S149-S149; doi:10.1016/j.ymthe.2006.08.451

391. De Novo Human Artificial Chromosome Formation Is Predetermined by Initial Chromatin Assembly and Transcriptional Patterns after Transfection

Hiroshi Nakashima, Megumi Nakano, Ryoko Ohnishi, Yasushi Hiraoka, Yasufumi Kaneda, Akio Sugino and Hiroshi Masumoto

Mol Ther 13: S149-S149; doi:10.1016/j.ymthe.2006.08.452

392. Duration of Expression of the Sleeping Beauty Transposase Gene in Mouse Liver Following Hydrodynamic Delivery

Jason B. Bell, Elena L. Aronovich, Brenda L. Koniar, Jeffrey M. Schreifels, Ann M. Clifford, Nathan D. Hoekstra and Perry B. Hackett

Mol Ther 13: S150-S150; doi:10.1016/j.ymthe.2006.08.453

393. Non-Viral Gene Transfer Using the Sleeping Beauty Transposon for Long-Term Gene Expression in the CNS of Neonatal Mice

Zachary L. Demorest, Walter C. Low, Andrew B. Freese and John R. Ohlfest

Mol Ther 13: S150-S150; doi:10.1016/j.ymthe.2006.08.454

394. Neuron-Specific, In Vivo Gene Delivery Mediated by Non-Viral Vectors

In-Kyu Park, Jurate Lasiene, Jennifer M. Knox, Shinn-Huey Chou, Philip J. Horner and Suzie H. Pun

Mol Ther 13: S151-S151; doi:10.1016/j.ymthe.2006.08.456

395. Role of Caveoli on Membrane Raft in the Internalization of Non-Viral Vectors

Peng H. Tan, Maria Manunta and Andrew J.T. George

Mol Ther 13: S151-S151; doi:10.1016/j.ymthe.2006.08.457

396. Quantitative Analysis of Non-Viral Gene Therapy in a Three-Dimensional Liver Bioreactor

Nathan Tedford, Jennifer Fang, Karel Domansky, Linda G. Griffith and Douglas A. Lauffenburger

Mol Ther 13: S151-S152; doi:10.1016/j.ymthe.2006.08.458

397. Compacted DNA Nanoparticles Transfect Cells by Binding to Cell Surface Nucleolin

Xuguang Chen and Pamela B. Davis

Mol Ther 13: S152-S152; doi:10.1016/j.ymthe.2006.08.459

398. Extracellular Matrix Identity and Surface Density Alter Transfection by Complexes Delivered from a Cell-Adhesive Substrate

Zain Bengali and Lonnie D. Shea

Mol Ther 13: S152-S153; doi:10.1016/j.ymthe.2006.08.460

399. Solid Nanobeads Prevents Polycations from Entering the Nuclei and Enhanced Transfection Efficiency

Wenzhong Li, Nan Ma, Leelee Ong, Alexander Kaminski, Peter Lorenz, Brigitte M. P|[uuml]|tzer, Ren-Ke Li, Christof Stamm and Gustav Steinhoff

Mol Ther 13: S153-S153; doi:10.1016/j.ymthe.2006.08.461

400. Peptide-Mediated Gene Transfer of Lipid/ DNA-Based Complexes to Cells Expressing CXC- Receptor 4

Wouter H. Driessen, Nobutaka Fujii, Hirokazu Tamamura and Sean M. Sullivan

Mol Ther 13: S153-S153; doi:10.1016/j.ymthe.2006.08.462

401. Quantitative Bioluminescence Imaging of Transgene Expression In Vivo

Garrett R. Rettig, Marie McAnuff, Dijie Liu, Ji-Seon Kim and Kevin G. Rice

Mol Ther 13: S154-S154; doi:10.1016/j.ymthe.2006.08.463

402. Intracellular Trafficking of QD-FRET Nanoparticles for Gene Delivery

Hunter H. Chen, Yi-Ping Ho, Tza-Huei Wang and Kam W. Leong

Mol Ther 13: S154-S154; doi:10.1016/j.ymthe.2006.08.464

403. Long-Term, High alpha-L-iduronidase Expression in MPS I Dogs Following Neonatal, Intravenous, Retroviral Vector Gene Therapy

Anne Traas, Ping Wang, Xiucui Ma, Patricia O'Donnell, Meg Sleeper, Gus Aguirre, Mark Haskins and Katherine P. Ponder

Mol Ther 13: S154-S155; doi:10.1016/j.ymthe.2006.08.466

404. Therapeutic Correction of PKU in a Mouse Model by Ectopic Expression of PAH and Its BH4- Cofactor Genes in Skeletal Muscle by a Recombinant Triple-Cistronic AAV2-Based Pseudotype 1 Vector

Zhaobing Ding, Cary O. Harding, Alexandre Rebuffat, Lina Elzaouk, Jon A. Wolff and Beat Thony

Mol Ther 13: S155-S155; doi:10.1016/j.ymthe.2006.08.467

405. Correction of the Murine Model of Hereditary Tyrosinemia Type I Using Messenger RNA as a Source of Transposase for Sleeping Beauty Mediated Integration of the FAH Gene

Andrew Wilber, Kirk J. Wangensteen, Yixin Chen, Lijuan Zhou, Joel L. Frandsen, Jason Bell, Zongyu Chen, Stephen C. Ekker, R. Scott McIvor and Xin Wang

Mol Ther 13: S155-S156; doi:10.1016/j.ymthe.2006.08.468

406. rAAV-Mediated Expression of Wnt10b cDNA Prevents the Development of Obesity in DIO Rats

George Aslanidi, Glenn Philipsberg, Vadim Kroutov, Kenneth Lamb, Erik Kohlbrenner, Martha Campbell-Thompson, Glenn Walter, Philip J. Scarpace and Sergei Zolotukhin

Mol Ther 13: S156-S156; doi:10.1016/j.ymthe.2006.08.469

407. A Single Unilateral Injection of AAV1-ASA and AAV1-FGE Vectors into the Hippocampus Results in Bilateral Expression and Widespread Distribution of ASA and Prevention of Sulfatide Storage in the Whole Brain of MLD Model Mice

Toshiyuki Kurai, Sanae Hisayasu, Yukihiko Hirai, Makoto Migita, Hidenori Suzuki and Takashi Shimada

Mol Ther 13: S156-S156; doi:10.1016/j.ymthe.2006.08.470

408. Safety of Lysosomal Enzymes Over-Expression in HSC for Gene Therapy of Storage Disorders

Alessandra Biffi, Ilaria Visigalli, Martina Cesani, Alessia Capotondo, Francesca R. Santoni de Sio, Isabella Pallavicini, Anna Zingale and Luigi Naldini

Mol Ther 13: S157-S157; doi:10.1016/j.ymthe.2006.08.471

409. Complete Correction of Enzymatic Deficiency and Lysosomal Storage throughout the Brain in a Mouse Model of GM1-gangliosidosis after Neonatal Intracerebroventricular Injection of an AAV1 Vector Encoding Lysosomal Acid Beta- galactosidase

Marike L. D. Broekman, Rena Baek, Laryssa A. Comer, Thomas N. Seyfried and Miguel Sena-Esteves

Mol Ther 13: S157-S157; doi:10.1016/j.ymthe.2006.08.472

410. Physiological Correction of Glycogen Storage Disease Type II Using Adeno-Associated Virus Serotype 1 Vectors

Cathryn Mah, Christina A. Pacak, Kerry O. Cresawn, Lara R. DeRuisseau, Sean Germain, Melissa A. Lewis, David D. Fuller and Barry J. Byrne

Mol Ther 13: S158-S158; doi:10.1016/j.ymthe.2006.08.473

411. The Metabolic Basis of Sexual Dimorphism in PKU Mice after PAH Gene Treatment

Li Chen and Savio L.C. Woo

Mol Ther 13: S158-S158; doi:10.1016/j.ymthe.2006.08.474

412. A Novel Friedreich's Ataxia Model and In Vivo Gene Rescue Using HSV-1 Amplicon Vectors in Transgenic Mice

Filip Lim, Gloria Palomo, Christina Mauritz, Alfredo Gimenez, Belen Illana, Francisco Wandosell and Javier Diaz-Nido

Mol Ther 13: S158-S158; doi:10.1016/j.ymthe.2006.08.476

413. Targeting the Low-Density Lipoprotein Receptor on the Blood-Brain Barrier for Transport of |[beta]|-Glucoronidase Can Treat the Neurological Degeneration of MPSVII

Brian J. Spencer and Inder M. Verma

Mol Ther 13: S159-S159; doi:10.1016/j.ymthe.2006.08.477

414. Non-Allele Specific RNA Interference in the CAG140 Knock-In Mouse Model of Huntington's Disease

Jodi L. McBride, Scott Q. Harper, Patrick D. Staber, Ines H. Martins, Haim Burstein, Richard W. Peluso, Barry Polisky, Barrie J. Carter and Beverly L. Davidson

Mol Ther 13: S159-S159; doi:10.1016/j.ymthe.2006.08.478

415. Stimulating Full-Length SMN2 Expression by Delivering Bi-Functional RNAs Via a Viral Vector

Travis D. Baughan, Monir Shababi, Gregory E. Tullis and Christian L. Lorson

Mol Ther 13: S159-S160; doi:10.1016/j.ymthe.2006.08.479

416. Gene Therapy for Parkinsons Disease by In Vivo Plasmid Transfer of Human Hepatocyte Growth Factor in Primate Model

Akihiko Ishida, Hiromi Koike and Ryuichi Morishita

Mol Ther 13: S160-S160; doi:10.1016/j.ymthe.2006.08.480

417. Combination Brain and Systemic Injections of AAV Results in Whole Body Therapy and Extension of Lifespan in the Niemann-Pick Mouse

Marco A. Passini, Jie Bu, Jonathan A. Fidler, Joseph W. Foley, James C. Dodge, Robin J. Ziegler, Wendy W. Yang, Jennifer Clarke, Tatyana V. Taksir, Denise A. Griffiths, Michael A. Zhao, Catherine R. O'Riordan, Lamya S. Shihabuddin, Edward H. Schuchman and Seng H. Cheng

Mol Ther 13: S160-S160; doi:10.1016/j.ymthe.2006.08.481

418. AAV-Mediated sFLT-1 Gene Therapy for Ocular Neovascularization: Longevity, Toxicity and Efficacy Results from Mice and Monkeys

E.P. Rakoczy, C.M. Lai, W.Y. Shen, M. Brankov, N. Barnett, S.Y. Lee, S.G. Leaver, I. Yeo, C.L. Ang and I.J. Constable

Mol Ther 13: S160-S161; doi:10.1016/j.ymthe.2006.08.482

419. Rescue of Cone Photoreceptors after Lentiviral Gene Transfer of Rpe65 cDNA in Knockout Mouse Models of Leber Congenital Amaurosis

Alexis-Pierre Bemelmans, Corinne Kostic, Dana Hornfeld, Meriem Tekaya, Sylvain V. Crippa, William W. Hauswirth, Janis Lem, Mathias Seeliger, Andreas Wenzel and Yvan Arsenijevic

Mol Ther 13: S161-S161; doi:10.1016/j.ymthe.2006.08.483

420. Hydrodynamic Limb Vein Delivery of Naked IGF-1 Plasmid DNA Provides Therapeutic Benefit in SOD1(G93A) Murine ALS Model

Gyula Acsadi, Roumen Anguelov, Xingli Li, Mary Kay Bates, Jon A. Wolff and Hans Herweijer

Mol Ther 13: S161-S161; doi:10.1016/j.ymthe.2006.08.484

421. Killing of Normal Cells Combined with TLR Engagement and CD40 Ligation Generates Autoimmune T Cell Reactivity Sufficient To Treat Large Established Tumors

Luis Sanchez-Perez, Gregory Daniels, Timothy Kottke, Rosa Maria Diaz, Jill Thompson, Heung Chong, Alan Melcher and Richard Vile

Mol Ther 13: S162-S162; doi:10.1016/j.ymthe.2006.08.486

422. Enhancement of Human Monocyte-Derived Dendritic Cell Functions by Adenovirus- Mediated RNA Interference of STAT-3

Tomoko Iwata, Hidetoshi Sumimoto, Hiroyuki Mizuguchi and Yutaka Kawakami

Mol Ther 13: S162-S162; doi:10.1016/j.ymthe.2006.08.487

423. Combination of Sleeping Beauty-Mediated INF-gamma Gene Transfer with CpG Oligodeoxynucleotides Provides Long-Term Survival of Intracranial Glioblastoma in Mice

Anhua Wu, Zachary L. Demorest, Isabelita Vengco, Wei Chen, Walter C. Low, Andrew B. Freese and John R. Ohlfest

Mol Ther 13: S162-S163; doi:10.1016/j.ymthe.2006.08.488

424. Myd88/TLR Signaling Is Required for Immunotherapy-Mediated Glioblastoma Regression

James F. Curtin, Gwendalyn D. King, Marianela Candolfi, Chunyan Liu, Kathrin S. Michelsen, Moshe Arditi, Tamer M. Fakhouri, Begonya Comin-Anduix, Antoni Ribas, Pedro R. Lowenstein and Maria G. Castro

Mol Ther 13: S163-S163; doi:10.1016/j.ymthe.2006.08.489

425. Translation of Enhanced Dendritic Cell Vaccines Using a CID-Inducible CD40 Receptor

Natalia Lapteva, Brent A. Hanks, Jianghong Jiang, Kevin M. Slawin and David M. Spencer

Mol Ther 13: S163-S164; doi:10.1016/j.ymthe.2006.08.490

426. dSLIM Immunomodulators Induce Anti- Tumor Responses Both In Vitro and In Vivo

Manuel Schmidt, Javier Cristobal, Astrid Sander, Bernadette Brzezicha, Sven A. Konig Merediz and Burghardt Wittig

Mol Ther 13: S164-S164; doi:10.1016/j.ymthe.2006.08.491

427. Adenovirus Mediated GRP94/gp96 Expression in Treatment of Neuroblastoma

Shanling Liu, Jiangao Zhu, He Wang, Takashi Kon and Chuan- Yuan Li

Mol Ther 13: S164-S164; doi:10.1016/j.ymthe.2006.08.492

428. Development of an Effective Safety Switch for Selective Elimination of Human T Cells In Vivo after Adoptive Transfer

Tom van Meerten, Henk Rozemuller, Wendy Mackus, Paul Parren, Jan van de Winkel, Marie-Jose Claessen, Rozemarijn van Rijn, Anton Hagenbeek, Anton Martens and Saskia Ebeling

Mol Ther 13: S164-S165; doi:10.1016/j.ymthe.2006.08.493

429. Adenoviral-Mediated Interleukin-15 Receptor-|[alpha]| Gene Therapy of Murine Breast Cancer

Brian J. Morrison, Yutaka Tagaya, Jason C. Steel, Poonam Mannan, Thomas A. Waldmann, John C. Morris and Yoshio Sakai

Mol Ther 13: S165-S165; doi:10.1016/j.ymthe.2006.08.494

430. EGFRvIII Retargeted Oncolytic Measles Virus Strains Have Significant Antitumor Activity Against Gliomas

Cory Allen, Sompong Vongpunsawad, Takafumi Nakamura, C. David James, Mark Schroeder, Roberto Cattaneo, Caterina Giannini, James Krempski, Stephen J. Russell and Evanthia Galanis

Mol Ther 13: S165-S166; doi:10.1016/j.ymthe.2006.08.496

431. Treatment of Multi-Focal CRC Liver Metastases with Repeated Infusion of Oncolytic Vesicular Stomatitis Virus Via the Hepatic Artery

Minoru Yamaki, Katsunori Shinozaki, Savio L.C. Woo and Toshimasa Asahara

Mol Ther 13: S166-S166; doi:10.1016/j.ymthe.2006.08.497

432. Characterization of a Novel Oncolytic Measles Virus Retargeted Against the Urokinase Receptor: In Vitro and In Vivo Studies

Jaime R. Merchan, Caili Tong, Takafumi Nakamura, Ianko Iankov and Stephen J. Russell

Mol Ther 13: S166-S167; doi:10.1016/j.ymthe.2006.08.498

433. Combination Therapy of Androgen-Independent Prostate Cancer Using a Prostate Restricted Replicative Adenovirus and a Replication-Defective Adenovirus Encoding Human Endostatin-Angiostatin Fusion Gene

Xiong Li, Sudhanshu P. Raikwar, You-Hong Liu, Sang-Jin Lee, Yan-Ping Zhang, Shaobo Zhang, Liang Cheng, Sang-Don Lee, Beth Elisa Juliar, Thomas A. Gardner, Meei-Huey Jeng and Chinghai Kao

Mol Ther 13: S167-S167; doi:10.1016/j.ymthe.2006.08.499

434. Oncolytic Virotherapy Using the HSV Mutant rQNestin34.5 towards CD133+ Brain Tumor Stem Cells

Akihiro Otsuki, Ankita Patel, Suzanne Camilli, Kazue Kasai, Sigeru Tanaka, E. Antonio Chiocca and Yoshinaga Saeki

Mol Ther 13: S167-S167; doi:10.1016/j.ymthe.2006.08.500

435. A Fiber-Modified, Relaxin-Expressing Oncolytic Adenovirus Prolongs Survival of Tumor Bearing Mice

Shanthi Ganesh, Melinda VanRoey, Neeraja Idamakanti and Karin Jooss

Mol Ther 13: S167-S168; doi:10.1016/j.ymthe.2006.08.501

436. Coxsackievirus A21 Has Potent Oncolytic Activity in Multiple Myeloma

Elizabeth M. Hadac and Stephen J. Russell

Mol Ther 13: S168-S168; doi:10.1016/j.ymthe.2006.08.502

437. An E1b-19kD-Deleted p53-Expressing Replicating Adenovirus Markedly Enhances the Induction of Apoptosis When Combined with Cisplatin in Head and Neck Cancer Cells

David I. Kutler, Harald Sauthoff, Jin Cheng, Yao Qi Huang, Sheila Heitner, William N. Rom and John G. Hay

Mol Ther 13: S168-S168; doi:10.1016/j.ymthe.2006.08.503

438. Targeting HSV-1 Virions for Specific Binding to Epidermal Growth Factor Receptor-VIII on Tumor Cells

Paola Grandi, Juliet Fernandez, Oscar Szentirmai, Robert Carter, Xandra O. Breakefield and Miguel Sena-Esteves

Mol Ther 13: S168-S168; doi:10.1016/j.ymthe.2006.08.504

439. Genetic Manipulation of Liver Sinusoidal Endothelial Cells (LSEC) and Repopulation of the Mouse Liver with Transplanted LSEC Has Therapeutic Implications

Antonia Follenzi, Daniel Benten, Marco Ulla, Michele De Palma, Phyllis Novikoff and Sanjeev Gupta

Mol Ther 13: S169-S169; doi:10.1016/j.ymthe.2006.08.506

440. Overexpression of Bcl-2 Prevented MSCs from Apoptosis and Improved Heart Function

Nan Ma, Wenzhong Li, Catharina Nesselmann, Leelee Ong, Alexander Kaminski, Brigitte M. P|[uuml]|tzer, Ren-Ke Li, Christof Stamm and Gustav Steinhoff

Mol Ther 13: S169-S169; doi:10.1016/j.ymthe.2006.08.507

441. Stable Oligo-to Polyclonal Hematopoiesis without Clonal Exhaustion Following Extended Reduced Intensity Selection of MGMT-P140K Expressing Murine Repopulating Stem Cells in Serially Transplanted Mice

C.R. Ball, I.H. Pilz, M. Schmidt, M. Schrempp, C. von Kalle and H. Glimm

Mol Ther 13: S169-S170; doi:10.1016/j.ymthe.2006.08.508

442. LV Expressing MR Reporter Genes Allows In Vivo Monitoring of Stem Cell Gene Therapy

Mario Amendola, Letterio S. Politi, Marcello Cadioli, Rossella Galli, Elena Binda, Andrea Falini, Sonia Levi, Giuseppe Scotti, Alessandra Biffi and Luigi Naldini

Mol Ther 13: S170-S170; doi:10.1016/j.ymthe.2006.08.509

443. Successful Long-Term Doxycycline-Regulated Transgene Expression in the Retina of Nonhuman Primates Following Subretinal Injection of Recombinant AAV Vectors

Knut Stieger, Guyl|[egrave]|ne Le Meur, Francoise Lasne, Michel Weber, Jack-Yves Deschamps, Delphine Nivard, Alexandra Mendes-Madeira, Nathalie Provost, Laurent Martin, Philippe Moullier and Fabienne Rolling

Mol Ther 13: S170-S170; doi:10.1016/j.ymthe.2006.08.510

444. Use of dsAAV8-Mediated Gene Transfer to Endogenous |[beta]|-Cells To Investigate the Therapeutic Efficacy of Immunoregulatory Gene Products in Preventing the Onset of Diabetes in NOD Mice

Khaja K. Rehman, Zhong Wang, Xiao Xiao and Paul D. Robbins

Mol Ther 13: S171-S171; doi:10.1016/j.ymthe.2006.08.511

445. Developmental Stage Determines Distribution of Organ Transduction after Intra-Amniotic Injection of Lentiviral Vector

Masayuki Endo, Tiago H. Coelho, Phil W. Zoltick and Alan W. Flake

Mol Ther 13: S171-S171; doi:10.1016/j.ymthe.2006.08.512

446. Inhibition of Hepatic Stellate Cell Activation and Liver Fibrosis by Expression of Cytoglobin In Vivo

Ruian Xu, Phillip Harrison, Xinyan Li, Miao Chen, Hua Li, Pik-to Cheung, Weidong Xiao and Farzin Farzaneh

Mol Ther 13: S171-S172; doi:10.1016/j.ymthe.2006.08.513

447. AP20187-Inducible Insulin-Like Effects in Diabetic Muscle and Liver Transduced with AAV

Gabriella Cotugno, Pietro Formisano, Ferdinando Giacco, Victor M. Rivera, Francesco Beguinot and Alberto Auricchio

Mol Ther 13: S172-S172; doi:10.1016/j.ymthe.2006.08.514

448. Suicide Gene-Mediated Conditional Ablation of Tumors Derived from Transplanted Embryonic Stem Cells

Juyeon Jung, Joanne Kim, Robert G. Pergolizzi and Ronald G. Crystal

Mol Ther 13: S172-S172; doi:10.1016/j.ymthe.2006.08.516

449. Sca-1+ Cell-Based Gene Therapy with a Modified Fibroblast Growth Factor 2 (FGF2) Increased Endosteal/Trabecular Bone Formation in Mice

Susan L. Hall, K.-H. William Lau, Shin-Tai Chen, Matilda H.-C. Sheng, Apurva K. Srivastava, Henry J. Klamut, Jon E. Wergedal, Daila S. Gridley, Subburaman Mohan and David J. Baylink

Mol Ther 13: S173-S173; doi:10.1016/j.ymthe.2006.08.517

450. Novel, Injectable, Genetically Engineered Stem Cell-Based System for Anterior Spinal Fusion

Rod J. Oskouian, Gadi Pelled, Yoram Zilberman, Yamit Tal, Zulma Gazit and Dan Gazit

Mol Ther 13: S173-S174; doi:10.1016/j.ymthe.2006.08.518

451. AAV-BDNF Augments Neurogenesis in Both the Normal Adult Rat Brain and the Quinolinic Acid Lesion Model of Huntington's Disease

Rebecca A. Henry, Stephanie M. Hughes, Richard L.M. Faull and Bronwen J. Connor

Mol Ther 13: S174-S174; doi:10.1016/j.ymthe.2006.08.519

452. Bone Marrow Stem Cells Are Potent Targets for Gene Therapy of Epidermolysis Bullosa, a Genetic Blistering Skin Disease

Katsuto Tamai, TaKehiko Yamazaki, Otsuru Satoru, Takenao Chino, Yasushi Kikuchi and Yasufumi Kaneda

Mol Ther 13: S174-S174; doi:10.1016/j.ymthe.2006.08.520

453. Injectionof Different Adult Cell Types into Mouse Myocardium Three Days after Myocardial Infarction Using a Novel Echo-Guided Technique Improves Cardiac Function

Yan Zhang, Junya Takagawa, Richard E. Sievers, Maelene L. Wong, Christian Heiss, Mohan N. Viswanathan, Neel K. Kapasi, Jianqin Ye, Elyse Foster, William Grossman, Matthew L. Springer and Yerem Yeghiazarians

Mol Ther 13: S175-S175; doi:10.1016/j.ymthe.2006.08.521

454. Recognition of Tumor Antigens by In Vitro Developed T Cells from Hematopoietic Stem Cells Retrovirally Transduced with TCR Genes

Yangbing Zhao, Zhili Zheng, Cyrille J. Cohen, Steven A. Rosenberg and Richard A. Morgan

Mol Ther 13: S175-S175; doi:10.1016/j.ymthe.2006.08.522

455. Genetically Engineered Adult Stem Cells and Hybrid Scaffolds as a Platform for Intervertebral Disc Regeneration

Nadav Kimelman, Rod J. Oskouian, Yoram Zilberman, Gadi Pelled, Zulma Gazit and Dan Gazit

Mol Ther 13: S175-S176; doi:10.1016/j.ymthe.2006.08.523

456. Gene Transfer to Skin Stem Cells by Early Gestational Intra-Amniotic Injection of Lentiviral Vector

Masayuki Endo, Phil W. Zoltick, William H. Peranteau, Mayumi Ito, George Cotsarelis and Alan W. Flake

Mol Ther 13: S176-S176; doi:10.1016/j.ymthe.2006.08.524

457. Reverse Transcriptase Deficient Retroviral Vectors for Transient Cell Modification

Melanie Galla, Axel Schambach, Elke Will and Christopher Baum

Mol Ther 13: S177-S177; doi:10.1016/j.ymthe.2006.08.526

458. Development of Non-Integrating and Site- Specifically Integrating Lentiviral Vectors

Luis Apolonia, Simon Waddington, Mary Collins, Adrian Thrasher and Nicola Philpott

Mol Ther 13: S177-S177; doi:10.1016/j.ymthe.2006.08.527

459. Murine Study To Evaluate Long-Term Transgene Expression of the MSCV-MGMTP140K wc Retroviral Vector in Support of a Phase I Gene Transfer Trial-Limitations of the Murine Model as a Pre-Clinical Tool

Elke Will, Jeff Bailey, Todd Schuesler, Brenden Balcik, Ben Burzynski, David Witte, Gerlinde Layh-Schmitt, Christof vonKalle, Christopher Baum, Brian P. Sorrentino, Lars M. Wagner, Lilith Reeves and David A. Williams

Mol Ther 13: S177-S178; doi:10.1016/j.ymthe.2006.08.528

Top

Abstracts

460. MGMTP140K Vector Constructs for Efficient In Vivo Enrichment of Genetically Corrected Cells Following Hematopoietic Cell Gene Transfer

U.R. Sorg, V. Kleff, G. Nagel, B. Opalka, J. Thomale, B. Kaina and T. Moritz

Mol Ther 13: S178-S178; doi:10.1016/j.ymthe.2006.08.529

461. Evaluation of In Vivo Model Systems for Safety Assessment of HIV-1 Based Lentiviral Vectors

Yuan Zhao, Selina Azam, Kenneth Keating and Robin Thorpe

Mol Ther 13: S178-S178; doi:10.1016/j.ymthe.2006.08.530

462. Comparison of EMCV IRES and FMDV 2A Cleavage Factor for Expression of Canine MGMT and a Second Transgene Using HIV-1 Vectors

Srinivas N. Kumar, Tatiana Zaboikina, Michail Zaboikin and Friedrich G. Schuening

Mol Ther 13: S179-S179; doi:10.1016/j.ymthe.2006.08.531

463. COX-2-Based Gene Therapy: Reduction of Intraocular Pressure in a Glaucoma Gene Therapy Animal Model with Lentiviral Vectors Expressing COX-2, a Prostaglandin Synthase, or a Prostaglandin Receptor

Roman A. Barraza and Eric M. Poeschla

Mol Ther 13: S179-S179; doi:10.1016/j.ymthe.2006.08.532

464. Use of Equine Infectious Anaemia Virus (EIAV) To Mediate Indoleamine 2,3-dioxygenase Gene Transfer to Murine Corneal Allograft Transplantation Model Results in Prolongation of Allograft Survival In Vivo with Little Immunogenicity

Peng H. Tan, Sven C. Beutelspacher and Andrew J.T. George

Mol Ther 13: S179-S180; doi:10.1016/j.ymthe.2006.08.533

465. Pseudotyping Lentiviral Vectors with a Modified GP64 Envelope Proteins Redirects Gene Transfer In Vitro and In Vitro

David Markusic, Niek van Til, Alexander Kanitz, Johan Hiralall, Ronald Oude-Elferink and Jurgen Seppen

Mol Ther 13: S180-S180; doi:10.1016/j.ymthe.2006.08.534

466. Comprehensive Analyses of Diverse Lentiviral and Retroviral Vectors for Post-Entry Restriction by TRIM5|[alpha]| and Implications for Gene Therapy

Dyana T. Saenz and Eric M. Poeschla

Mol Ther 13: S180-S180; doi:10.1016/j.ymthe.2006.08.535

467. Lentiviral Vector (LV) Non-Coding Elements That Impart High Titers and Expression to |[beta]|-Globin (h|[beta]|) Cassettes

F. Urbinati, P. Xia, A. Perumbeti, M. Xia, A. Corsinotti, A. Zarzuela, N. Perelman and P. Malik

Mol Ther 13: S181-S181; doi:10.1016/j.ymthe.2006.08.536

468. Evaluation of Factors Influencing the Production Titers of SIV-Derived Lentiviral Vectors

Nora Naumann, Suk See De Ravin, Morvarid Moayeri, Uimook Choi, Yasuhiro Ikeda and Harry L. Malech

Mol Ther 13: S181-S181; doi:10.1016/j.ymthe.2006.08.537

469. Optimization of the Lentivirus Vector Containing the MSCV-U3 and EF1|[alpha]| Double Internal Promoters

Naoya Uchida, Hideki Hanawa, Motoko Yamamoto and Takashi Shimada

Mol Ther 13: S182-S182; doi:10.1016/j.ymthe.2006.08.538

470. ABCB4 P-Glycoprotein Reduces Infectivity of Lentiviral Particles by Increasing Their Phosphatidylcholine Content

Niek P. van Til, Kirstin Heutinck, Ronald P.J. Oude Elferink and Jurgen Seppen

Mol Ther 13: S182-S182; doi:10.1016/j.ymthe.2006.08.539

471. Chimeric Lentiviral Vectors with Safety Insurance

Kritika Kachapati, Geetanjali Sachdeva and Suresh Arya

Mol Ther 13: S182-S183; doi:10.1016/j.ymthe.2006.08.540

472. Biodistribution of Semliki Forest Virus Vectors and Effect of Preimmunizations in Mice

Juan R. Rodriguez, Erkuden Casales, Jesus Prieto and Cristian Smerdou

Mol Ther 13: S183-S183; doi:10.1016/j.ymthe.2006.08.541

473. Semliki Based Systems for the Production of Retroviral Vectors: A Safety Concern

Eric Piver, Christine Collin, No|[eacute]|mie Renault, Thierry Bru and Jean-Christophe Pages

Mol Ther 13: S183-S183; doi:10.1016/j.ymthe.2006.08.542

474. Deletion of All Membranous Genes of Recombinant Sendai Virus Results in the Dramatic Reduction of Toxicity for Pulmonary Gene Transfer in Neonatal Mice

Sakura Tanaka, Yoshikazu Yonemitsu, Mamoru Hasegawa, Tomoaki Taguchi and Katsuo Sueishi

Mol Ther 13: S184-S184; doi:10.1016/j.ymthe.2006.08.543

475. SeV-Mediated Gene Transfer after Three Re-Administrations in Mice and Sheep

Uta Griesenbach, Gerry McLachlan, Lucinda Somerton, David Collie, Makoto Inoue, Takashi Hironaka, Seng Cheng, Ronald Scheule, Toshiyuki Owaki, Alison Baker, Peter Tennant, Mamoru Hasegawa and Eric W.F.W. Alton

Mol Ther 13: S184-S184; doi:10.1016/j.ymthe.2006.08.544

476. In Vivo Repopulation of Syngenic Hematopoietic Cells Expressing GFP Transfected by Recombinant Sendai Virus |[ndash]| Toward Development of 'Cytoplasmic Gene Therapy' for Hematopoietic Disorders

Kumi Yoshida, Yoshikazu Yonemitsu, Mamoru Haswgawa and Katsuo Sueishi

Mol Ther 13: S185-S185; doi:10.1016/j.ymthe.2006.08.545

477. Replication Deficiency: The Safety Record of a New Sendai Virus Vector Generation

Sascha Bossow, Sabine Schlecht, Marian Wiegand and Wolfgang J. Neubert

Mol Ther 13: S185-S185; doi:10.1016/j.ymthe.2006.08.546

478. Novel Gene Delivery System of Sendai Virus Vector-Transduced Human Peripheral Monocytes

Tomoko Tanaka, Kashiya Takasugi, Ryo Kurita, Takafumi Nakamura, Makoto Inoue, Mamoru Hasegawa, Fumiko Ono, Keiji Terao, Yasuhiro Yoshikawa and Kenzaburo Tani

Mol Ther 13: S185-S186; doi:10.1016/j.ymthe.2006.08.547

479. Development and Characterization of a New Noncytopathic Vector Derived from Semliki Forest Virus

Erkuden Casales, Juan R. Rodriguez-Madoz, Nerea Razquin, Yolanda Cuevas, Jesus Prieto and Cristian Smerdou

Mol Ther 13: S186-S186; doi:10.1016/j.ymthe.2006.08.548

480. Gene Transfer to Gut K Cells for Physiologic Insulin Replacement in Diabetes

Eric C. Hsu, Scott Pownall, Timothy J. Kieffer, Yvonne Luu, Simon Leong, Paul D. Robbins, Xiao Xiao and Anthony T. Cheung

Mol Ther 13: S186-S186; doi:10.1016/j.ymthe.2006.08.549

481. EPIDEMIOLOGY of Seneca Valley Virus (SVV-001), a Novel Oncolytic Picornavirus for the Systemic Treatment of Patients with Solid Cancers with Neuroendocrine Features

Laura M. Hales, Brian H. Jones, Ann-Jeanette Vasko, Nick J. Knowles, Seshidar R. Police and Paul L. Hallenbeck

Mol Ther 13: S187-S187; doi:10.1016/j.ymthe.2006.08.550

482. T Cells as Carriers for Systemic Measles Virotherapy of Multiple Myeloma

Hooi T. Ong, Kosei Hasegawa, Mary Harvey, Allan Dietz, Stephen J. Russell and Kah-Whye Peng

Mol Ther 13: S187-S187; doi:10.1016/j.ymthe.2006.08.551

483. Phenotypic Correction of Von Willebrand Disease Type 3 Blood-Derived Endothelial Cells with Lentiviral Vectors Expressing Von Willebrand Factor

Simon F. DeMeyer, Karen Van hoorelbeke, Marinee K. Chuah, Inge Pareyn, Veerle Gilijns, Robert P. Hebbel, D|[eacute]|sir|[eacute]| Collen and Thierry Vandendriessche

Mol Ther 13: S187-S187; doi:10.1016/j.ymthe.2006.08.552

484. Murine Liver as a Model for AAV Replication, Recombination and Evolution

Xun Sun, You Lu, Gaung-Ping Gao, Michael T. Korn, Julio SanMiguel, Martin W. Lock and James M. Wilson

Mol Ther 13: S187-S188; doi:10.1016/j.ymthe.2006.08.554

485. Long-Term In Vivo Engraftment & Transgene Expression from CD34+ Human Hematopoietic Stem Cells Transduced with Pseudotyped rAAV

Sarah Hardy, Margaret Heerwagen, Lane Bilbrey, Kamehameha K. Wong and Saswati Chatterjee

Mol Ther 13: S188-S188; doi:10.1016/j.ymthe.2006.08.555

486. Efficient and Selective Gene Transfer Directed to Muscle by Tropism-Modified Adeno-Associated Virus Vector

Chi-Yi Yu, Bing Wang, Zhong Wang, Zhongren Cao, Juan Li and Xiao Xiao

Mol Ther 13: S188-S189; doi:10.1016/j.ymthe.2006.08.556

487. Liver-Targeted Gene Therapy in Glycogen Storage Disease Type Ia (GSD-Ia) Requires Widespread, Regulated Glucose-6-phosphatase

Dwight D. Koeberl, Lopamudra Banerjee, Andrew Bird, Baodong Sun and Y.T. Chen

Mol Ther 13: S189-S189; doi:10.1016/j.ymthe.2006.08.557

488. Adeno-Associated Viral Serotype 2/1 Is a Highly Efficient Vector for In Utero Gene Transfer to Hair Cell Precursors

Jeffrey C. Bedrosian, Michael Anne Gratton, John V. Brigande, Waixing Tang and Jean Bennett

Mol Ther 13: S189-S189; doi:10.1016/j.ymthe.2006.08.558

489. Treatment for Hemophilia B Using Self-Complimentary AAV8 Vectors

Micheal L. Hebert, Dirk Grimm, Theresa A. Storm and Mark A. Kay

Mol Ther 13: S189-S190; doi:10.1016/j.ymthe.2006.08.559

490. Successful Readministration of AAV8 Following Administration of Nondepleting CD4 Antibody at the Time of Vector Administration

Jenny H. McIntosh, Melanie Cochrane, Arnold Prizzey, Herman Waldmann, Andrew M. Davidoff and Amit C. Nathwani

Mol Ther 13: S190-S190; doi:10.1016/j.ymthe.2006.08.560

491. Mosaic AAV Vectors Display Novel Properties for Neuronal Transduction

Stanley G. LeRoy, Laryssa A. Comer, Fabricio F. Costa, Marike L.D. Broekman and Miguel Sena-Esteves

Mol Ther 13: S190-S190; doi:10.1016/j.ymthe.2006.08.561

492. Biodistribution and Integration Assessment of AAV1 gag-PR-RT(|[Delta]|RNaseH) after Intramuscular Administration in Rabbits

Bruce C. Schnepp, Michael C. Soult, Tara Allen, Pervin Anklesaria, Philip R. Johnson and Keith Munson

Mol Ther 13: S190-S191; doi:10.1016/j.ymthe.2006.08.562

493. High Efficiency Gene Targeting to Mammalian Joint Tissue Using Self- Complementary Adeno-Associated Viral Vector Serotypes

Laurie R. Goodrich, Vivian W. Choi, Beth C. DudaCarbone, C. Wayne McIlwraith and Richard J. Samulski

Mol Ther 13: S191-S191; doi:10.1016/j.ymthe.2006.08.563

494. Optimizing the Mannitol-Facilitated CNS Entry of Peripherally-Delivered AAV2 Vector

Haiyan Fu, Julianne DiRosario and Douglas M. McCarty

Mol Ther 13: S191-S191; doi:10.1016/j.ymthe.2006.08.564

495. Transfer of LEDGF to the Mouse Retina Via Systemic AAV Vector Administration

Lyudmyla G. Glushakova, Marina Gorbatuyk, Yuanging Lu, Sihong Song, Min Zheng, Toshimichi Shinohara and William W. Hauswirth

Mol Ther 13: S192-S192; doi:10.1016/j.ymthe.2006.08.565

496. AAV-Mediated, Somatic Gene Transfer to RPE Cells in Order To Study the Pathogenesis of Macular Degeneration: Proteomic and Genomic Analysis

Garrett C. Du Bois, Petya D. Radoeva and Jean Bennett

Mol Ther 13: S192-S192; doi:10.1016/j.ymthe.2006.08.566

497. Central CART Gene Delivery by Recombinant AAV Vector Decreases Lean Body Mass in Diet-Induced Obese Male Rats

Keyun Qing and Yanyun Chen

Mol Ther 13: S192-S193; doi:10.1016/j.ymthe.2006.08.567

498. AAV |[Delta]|264CFTR Enhances Maturation of |[Delta]|F508CFTR and wt CFTR Expression

Liudmila Cebotaru, Terence R. Flotte and William B. Guggino

Mol Ther 13: S193-S193; doi:10.1016/j.ymthe.2006.08.568

499. Improving the Stability of Ad-AAV Hybrid Vectors

Haim Burstein, Richard Peluso, Ziv Sandalon, Kurt Lustig and Tony Stepan

Mol Ther 13: S193-S193; doi:10.1016/j.ymthe.2006.08.569

500. Tetanus Toxin Heavy Chain-Streptoavidin Fusion Protein for Targeted Motor Neuron Gene Delivery through Metabolically Biotinylated AAV

Qingshan Teng, Jeffrey S. Bartlett, Thais Federici, Jun Yang and Nicholas M. Boulis

Mol Ther 13: S193-S193; doi:10.1016/j.ymthe.2006.08.570

501. RheoSwitch|[reg]| Therapeutic System-Inducible Recombinant AAV Vectors for Tightly Regulated Transgene Expression

Dawn Karzenowski, Zhijian J. Chen, David W. Potter and Malla Padidam

Mol Ther 13: S194-S194; doi:10.1016/j.ymthe.2006.08.571

502. Advances in the Application of Combinatorial Technology for the Optimization of Adeno-Associated Virus (AAV) Vectors

Luca Perabo, Jan Endell, Stephan Maersch, Michael Hallek and Hildegard Buening

Mol Ther 13: S194-S194; doi:10.1016/j.ymthe.2006.08.572

503. A Novel Herpes Simplex Virus Helper Based Production of Adeno-Associated Virus Vectors for Treatment of Retinal Angiogenesis

Guo-jie Ye, Chris Drogemuller, Darby Thomas, Marina Scotti, Wen Kang, David Knop, Sanford Boye, Peter Pechan, James Peterson, William Hauswirth, Abraham Scaria and Samuel Wadsworth

Mol Ther 13: S194-S194; doi:10.1016/j.ymthe.2006.08.573

504. Neuronal Affinity of a C7C Loop Peptide Identified through Phage Display

Thais Federici, James K. Liu, Qingshan Teng, Mary Garrity-Moses, Jun Yang and Nicholas M. Boulis

Mol Ther 13: S195-S195; doi:10.1016/j.ymthe.2006.08.574

505. Advances in Large-Scale Production of Recombinant Adeno-Associated Vectors

Alejandro Negrete, Masashi Urabe Urabe and Robert M. Kotin

Mol Ther 13: S195-S195; doi:10.1016/j.ymthe.2006.08.575

506. Production of Recombinant Adeno-Associated Virus Type 1 Vector Using a Herpes Simplex Virus Based System

Wen Kang, Chris Drogemuller, Marina M. Scotti and Guo-jie Ye

Mol Ther 13: S195-S195; doi:10.1016/j.ymthe.2006.08.576

507. Engineering a Novel AAV Variant for Purification Via Immobilized Metal Affinity Chromatography

James T. Koerber, Jae-Hyung Jang Jang, Julie Yu, Ravindra Kane and David V. Schaffer

Mol Ther 13: S196-S196; doi:10.1016/j.ymthe.2006.08.577

508. Development of Optimized AAV2 Vector Biosynthesis and Purification Processes To Support High Capacity Production of Clinical Vectors of High Purity and Potency

Bernd Hauck, Jitin Bajaj, Sonali Joyce, Guang Qu, Olga A. Zelenaia, Katherine A. High and J. Fraser Wright

Mol Ther 13: S196-S196; doi:10.1016/j.ymthe.2006.08.578

509. Adeno-Associated Vector Mediated Delivery of Anti-HIV Genes

Mayur C. Tamhane and Ramesh Akkina

Mol Ther 13: S196-S196; doi:10.1016/j.ymthe.2006.08.579

510. Detection and Quantification of rcAAV in rAAV Stocks by Real-Time qPCR

Traci L. Mayfield, Irina Korytov, Joyce D. Francis, David R. Knop and Richard O. Snyder

Mol Ther 13: S196-S197; doi:10.1016/j.ymthe.2006.08.580

511. An Enzyme Linked Immunosorbent Assay for the Detection of Herpes Simplex Virus Type 1 Proteins in a Novel rAAV Production and Purification Process

Guo-jie Ye and Tammy Mandell

Mol Ther 13: S197-S197; doi:10.1016/j.ymthe.2006.08.581

512. Characterization of Adsorption of Adeno-Associated Virus to Commonly Used Catheter Materials: AAV2 vs. AAV1/2

Daisy P. Cross and Marty Morris

Mol Ther 13: S197-S197; doi:10.1016/j.ymthe.2006.08.582

513. A Simple Method To Ensure Titer Conservation of AAV2 Vector Preparations Delivered with Stainless Steel Needles

Elias T. Ketchum, Kevin Kwok, Anthony Ramirez, Junshan Hao, Brian Kruegel, Dominick Vacante, Raymond Bartus and Mehdi Gasmi

Mol Ther 13: S197-S198; doi:10.1016/j.ymthe.2006.08.583

514. mRNA Transfection Results in Efficient Overexpression of Transgenes in Leukemic Cell Lines and Hematopoietic Stem Cells

Martin F. Ryser, Marcus Gentsch, Fernando Ugarte, Harry L. Malech and Sebastian Brenner

Mol Ther 13: S198-S198; doi:10.1016/j.ymthe.2006.08.585

515. Sequence Requirements for Alveolar Epithelial Cell-Specific Plasmid Nuclear Import

James V. DeGiulio and David A. Dean

Mol Ther 13: S198-S198; doi:10.1016/j.ymthe.2006.08.586

516. Development of a Minicircle Vector Free of Plasmid Bacterial DNA Sequences and Capable of |[oslash]|C31-Mediated Site-Specific Integration

Zhi-Ying Chen, Cheng-Yi He, Anja Ehrhardt, Hui Xu and Mark A. Kay

Mol Ther 13: S198-S199; doi:10.1016/j.ymthe.2006.08.587

517. Lipopolythioureas: Non Cationic System for Gene Delivery

Jeanne Leblond, Nathalie Mignet, Maria-Vittoria Spanedda, Daniel Scherman and Jean Herscovici

Mol Ther 13: S199-S199; doi:10.1016/j.ymthe.2006.08.588

518. Mechanism of Difference in the Transcription Activity of Nucleus-Delivered Transgene Introduced by Adenovirus and Lipoplex

Hidetaka Akita, Susumu Hama, Hiroyuki Mizuguchi and Hideyoshi Harashima

Mol Ther 13: S199-S199; doi:10.1016/j.ymthe.2006.08.589

519. Development of S/MAR Plasmid Vectors for Persistent Expression and Maintenance, In Vivo

Orestis Argyros, Suet-Ping Wong, Andrew A. Miller and Richard Harbottle

Mol Ther 13: S199-S200; doi:10.1016/j.ymthe.2006.08.590

520. ProTIS, a Method for Prediction of Insertion-Site Preferences into Chromosomes of Vectors Used for Gene Therapy

Aron M. Geurts, Christopher S. Hackett, Jason B. Bell, Tracy L. Bergemann, Lara S. Collier, Corey M. Carlson, David A. Largaespada and Perry B. Hackett

Mol Ther 13: S200-S200; doi:10.1016/j.ymthe.2006.08.591

521. Gene Transfer of an Anti-CCR5 siRNA by Sleeping Beauty (SB) Transposon System

Mayur C. Tamhane and Ramesh Akkina

Mol Ther 13: S200-S200; doi:10.1016/j.ymthe.2006.08.592

522. Neural Retina Limits Delivery Non Viral Vectors to Retinal Pigment Epithelium

Liesbeth Peeters, Niek Sanders, Koen Boussery, Johan Van de Voorde, Joseph Demeester and Stefaan De Smedt

Mol Ther 13: S200-S201; doi:10.1016/j.ymthe.2006.08.593

523. Deoxyribonuclease I and Endonuclease G Are Host Defense Enzymes Responsible for Inactivation of Foreign DNA in Kidney Tubular Epithelial Cells

Timea Buzder, Xiaoyan Yin, Xiaoying Wang, Gaspar Banfalvi and Alexei G. Basnakian

Mol Ther 13: S201-S201; doi:10.1016/j.ymthe.2006.08.594

524. Analysis of Unique Proteins Bound to Sequentially Injected DOTAP:DNA Vectors

Christine C. Conwell and Leaf Huang

Mol Ther 13: S201-S201; doi:10.1016/j.ymthe.2006.08.595

525. Mutants of phiC31 Integrase with Increased Efficiency and Specificity

Annahita Keravala, Solomon Lee, Eric C. Olivares, Bhaskar Thyagarajan, Alfonso Farruggio, Vanessa E. Gabrovsky and Michele P. Calos

Mol Ther 13: S201-S202; doi:10.1016/j.ymthe.2006.08.596

526. Induction of Apoptosis in Melanoma Cell Lines by the Noxa Gene

Mohamed Hassan, Amine Alaoui, Alireza Mirmohammadsadegh, Alessandra Marini, Sandeep Nambiar and Ulrich R. Hengge

Mol Ther 13: S202-S202; doi:10.1016/j.ymthe.2006.08.597

527. Pharmaceutical Plasmid Manufacturing: Development of Economical and Innovative Process Solutions

Joachim Schorr, Markus Mueller, Juergen Hubbuch and Andreas Frerix

Mol Ther 13: S202-S202; doi:10.1016/j.ymthe.2006.08.598

528. Significant Silencing Effect of a Multifunctional Envelope-Type Nano Device Encapsulating Antisense Oligodeoxynucleotide and Double-Stranded siRNA

Kentaro Kogure, Yoshio Nakamura, Ikramy A. Khalil, Shiroh Futaki and Hideyoshi Harashima

Mol Ther 13: S202-S203; doi:10.1016/j.ymthe.2006.08.599

529. Development of Novel Systemic Gene Delivery System for Cancer Therapy with Tumor-Specifically Cleavable PEG-Lipid

Hiroto Hatakeyama, Hidetaka Akita, Kentaro Kogure, Motoi Oishi, Yukio Nagasaki, Hideo Kobayashi, Hiroshi Kikuchi and Hideyoshi Harashima

Mol Ther 13: S203-S203; doi:10.1016/j.ymthe.2006.08.600

530. The Effects DNA Molecular Weights and Conformations on Cell Uptake and the Binding Interaction with Cationic Polymers Used for Non-Viral Gene Delivery

Charlie Y.-M. Hsu, Cezary Kucharski and Hasan Uludag

Mol Ther 13: S203-S204; doi:10.1016/j.ymthe.2006.08.601

531. Complexes of DNA-Cationic Liposomes with Baculovirus GP64 Envelope Fusion Protein Vesicles Demonstrate Enhanced Transfection Efficiency

Ghiabe H. Guibinga, Shaochun Song, Jeanne Loring and Theodore Friedmann

Mol Ther 13: S204-S204; doi:10.1016/j.ymthe.2006.08.602

532. An Inducible Fed-Batch Fermentation Process for Scale-Up and Production of DNA Vaccines and Gene Medicines

Aaron E. Carnes, James A. Williams and Clague P. Hodgson

Mol Ther 13: S204-S204; doi:10.1016/j.ymthe.2006.08.603

533. Recombinant (KHG)6-FGF2 Biopolymer for Targeted Gene Transfer

Arash Hatefi and Hamid Ghandehari

Mol Ther 13: S204-S205; doi:10.1016/j.ymthe.2006.08.604

534. Silk-Elastinlike Polymers for Matrix-Mediated Adenoviral Gene Delivery

Arash Hatefi and Hamid Ghandehari

Mol Ther 13: S205-S205; doi:10.1016/j.ymthe.2006.08.605

535. Physicochemical and Transfection Properties of Cationic Hydroxyethylcellulose/DNA Nanoparticles

Farzaneh Fayazpour, Bart Lucas, Carmen Alvarez-Lorenzo, Niek Sanders, Joseph Demeester and Stefaan De Smedt

Mol Ther 13: S206-S206; doi:10.1016/j.ymthe.2006.08.606

536. Charge Switchable Helper Lipids for Gene Delivery

Mark W. Grinstaff, Carla A. Hernandez Prata, Yougen Li, Dan Luo and Tom J. MacIntosh

Mol Ther 13: S206-S206; doi:10.1016/j.ymthe.2006.08.607

537. Charge-Reversal Lipids for Gene Transfection

Mark W. Grinstaff, Carla A. Hernandez Prata, Steven R. Meyers, Philippe Barthelemy, Yougen Li, Dan Luo, Tom J. McIntosh and Stephen J. Lee

Mol Ther 13: S206-S207; doi:10.1016/j.ymthe.2006.08.608

538. DNAvaletTM Transfection Reagent

Carla Prata

Mol Ther 13: S207-S207; doi:10.1016/j.ymthe.2006.08.609

539. Unraveling the Mechanisms Underlying Silencing/Activation of Episomal Vectors In Vivo

Efren Riu, Zhi-Ying Chen and Mark A. Kay

Mol Ther 13: S207-S207; doi:10.1016/j.ymthe.2006.08.610

540. Genetic Intervention towards Improving the Long Term Outcome of CABG Using a Lipid Peptide DNA Vector System

Scott A. Irvine, Faiza Afzal, Qing H. Meng, Jimmy Ho, Andrew Wu, Jean R. McEwan and Stephen L. Hart

Mol Ther 13: S207-S208; doi:10.1016/j.ymthe.2006.08.611

541. Species-Specific Characteristics in Muscle Resistance and Their Impact on In Vivo Electroporation

Amir S. Khan, Patricia A. Brown, Melissa A. Pope and Ruxandra Draghia-Akli

Mol Ther 13: S208-S208; doi:10.1016/j.ymthe.2006.08.613

542. Development and Characterization of Ultrasound Responsive Microbubbles for Gene Delivery

Ine Lentacker, Stefaan C. De Smedt, Joseph Demeester and Niek N. Sanders

Mol Ther 13: S208-S209; doi:10.1016/j.ymthe.2006.08.614

543. Monitoring Transgene Expression by Radio-Peptide Positron Emission Tomography

Amiq Gazdhar, Murat Bilici, Erick Ayuni, Thomas Krause, Michal Hofmann and Raplh A. Schmid

Mol Ther 13: S209-S209; doi:10.1016/j.ymthe.2006.08.615

544. PLGA Nanoparticles for DNA Vaccination |[ndash]| Waiving Complexity and Increasing Efficiency

Jacob Gvili and Marcelle Machluf

Mol Ther 13: S209-S209; doi:10.1016/j.ymthe.2006.08.616

545. Comparison between Different Tissues for Efficient and Safe DNA Electrotransfer In Vivo

Franck M. Andre and Lluis M. Mir

Mol Ther 13: S210-S210; doi:10.1016/j.ymthe.2006.08.617

546. Targeted Non-Viral Gene Delivery Using Microbubbles and Focused Ultrasound

Ahad Rahim, Sarah L. Taylor, Nigel L. Bush, Gail R. ter Haar, Jeff C. Bamber and Colin D. Porter

Mol Ther 13: S210-S210; doi:10.1016/j.ymthe.2006.08.618

547. Magnetically Driven Non-Viral Gene Delivery Efficiently Transfects Cultured Smooth Muscle Cells and Inhibits Their Growth Via Adiponectin Transgene Expression

Boris Polyak, Michael Chorny, Ivan Alferiev, Kenneth Walsh, Gary Friedman and Robert J. Levy

Mol Ther 13: S211-S211; doi:10.1016/j.ymthe.2006.08.619

548. Cellular Defense Response in Transduced and Transfected Human Tumor and Primary Cell Lines

Riikka Pellinen, Outi Rautsi, Saara Lehmusvaara, Sillanp|[auml]||[auml]| Maarit, Hakkarainen Tanja, V|[auml]|h|[auml]|kangas Elisa, Yl|[auml]|-herttuala Seppo, Hinkkanen Ari, Julkunen Ilkka and Wahlfors Jarmo

Mol Ther 13: S211-S211; doi:10.1016/j.ymthe.2006.08.620

549. Ultrasound with Microbubbles Enhances Gene Expression of Plasmid DNA Delivered through Portal Vein Injection

Zhenping Shen, Andrew A. Brayman, Liping Chen and Carol H. Miao

Mol Ther 13: S212-S212; doi:10.1016/j.ymthe.2006.08.621

550. Delivery of Oligodeoxynucleotides into Human Saphenous Veins and the Adjunct Effect of Ultrasound and Microbubbles

Tetsuya Kodama, Peng H. Tan, Andrew J.T. George and Martin J.K. Blomley

Mol Ther 13: S212-S212; doi:10.1016/j.ymthe.2006.08.622

551. The Use of Electroporation To Transfer Plasmids to the Lung Results in Reduced TLR9 Signaling and Inflammation

Rui Zhou, James E. Norton, Ning Zhang and David A. Dean

Mol Ther 13: S212-S213; doi:10.1016/j.ymthe.2006.08.623

552. Collateral Circulation under Cerebral Ischemia by Hypoxia Inducible Factor Naked DNA in Rat Indirect-Bypass Model

Mitsuhiro Anan, Tatsuya Abe, Takeshi Matsuda, Ryo Inoue, Keisuke Ishii, Minoru Fujiki and Hidenori Kobayashi

Mol Ther 13: S213-S213; doi:10.1016/j.ymthe.2006.08.624

553. Development of Echo-Contrast Gas Entrapping Liposome as Gene and siRNA Delivery Tool

Yoichi Negishi, Tetsuya Fukuyama, Yoko Endo, Ryo Suzuki, Kumiko Tanaka, Kaori Sawamura, Tomoko Takizawa, Kazuo Maruyama and Yukihiko Aramaki

Mol Ther 13: S213-S213; doi:10.1016/j.ymthe.2006.08.625

554. Improved Efficiency of Gene Expression Using the Stiletto|[trade]| Endocardial Direct Injection Catheter

Samuel J. Epstein, Wendy Naimark, Maria Palasis, Kian K. Poh, Tengiz Tkebuchava, Corinne Luedemann and Douglas Losordo

Mol Ther 13: S213-S214; doi:10.1016/j.ymthe.2006.08.626

555. Large-Scale, Flow-Based Electroporation To Deliver Engineered Zinc Finger Protein Nucleases That Mediate High-Efficiency Disruption of the Human CCR5 Gene

Michael C. Holmes, Linda Liu, Elena Perez, Linhong Li, Rama Shivakumar, Cornell Allen, Olga Liu, Jeffrey C. Miller, Fyodor D. Urnov, Kenneth Kim, Edward J. Rebar, Dale Ando, Philip D. Gregory, James Riley, Madhusudan Peshwa and Carl June

Mol Ther 13: S214-S214; doi:10.1016/j.ymthe.2006.08.627

556. Proteasome Inhibitors Increase Cationic-Lipid Mediated Gene Transfer in A549 Cells In Vitro

Uta Griesenbach, Maresa Brake, Aaron Gardner and Eric W.F.W. Alton

Mol Ther 13: S214-S214; doi:10.1016/j.ymthe.2006.08.628

557. A Study of AAV2/1/SERCA2a Delivered Via the V-Focus Cardiac Delivery System in an Ovine Pacing Model of Heart Failure

Melissa J. Byrne, David Kaye and John M. Power

Mol Ther 13: S214-S215; doi:10.1016/j.ymthe.2006.08.629

558. High Efficiency Transfection of Primary Cells for Basic Research and Gene Therapy

Hans-Guenter Bruenker

Mol Ther 13: S215-S215; doi:10.1016/j.ymthe.2006.08.630

559. A Pseudo-Exon Derived from an Intronic Insertion is Responsible for Duchenne-Like Muscular Dystrophy in the Welsh Corgi Dog

Bruce F. Smith and Joseph N. Kornegay

Mol Ther 13: S215-S215; doi:10.1016/j.ymthe.2006.08.632

560. GNE Gene Replacement in Hereditary Inclusion Body Myopathy

Phillip B. Maples, Daniel Darvish, Gregory Nemunaitis, Esther Chang, Julie Ogden and John Nemunaitis

Mol Ther 13: S215-S216; doi:10.1016/j.ymthe.2006.08.633

Top

Abstracts

561. Novel Tissue-Specific Regulatory Cassettes Direct High-Level Transgene Expression in Skeletal and Cardiac Muscle

Maja Z. Salva, Charis L. Himeda, Phillip Tai, Eiko Nishiuchi, Eric E. Finn, James M. Allen, Paul Gregorevic, Michael J. Blankinship, Leonard A. Meuse, Jeffrey S. Chamberlain and Stephen D. Hauschka

Mol Ther 13: S216-S216; doi:10.1016/j.ymthe.2006.08.634

562. Ex Vivo Gene Therapy for Duchenne Muscular Dystrophy: Lentiviral Vectors, Exon Skipping and PhiC31 Integrase Approaches

Simon P. Quenneville, Pierre Chapdelaine, Joel Rousseau and Jacques P. Tremblay

Mol Ther 13: S216-S216; doi:10.1016/j.ymthe.2006.08.635

563. Correction of Glycogen Storage Disease Type II by Systemic Delivery of an AAV2/8 Vector Containing a Muscle-Specific Promoter

Baodong Sun, Ping Li, Brown Talmage, Bird Andrew, Zhen Yan and Dwight D. Koeberl

Mol Ther 13: S217-S217; doi:10.1016/j.ymthe.2006.08.636

564. Correction of Hyposialylation in Hereditary Inclusion Body Myopathy, by Ex-Vivo Therapy

Zo|[eacute]| Coulombe, Dominic Gagn|[eacute]| and Jacques P. Tremblay

Mol Ther 13: S217-S217; doi:10.1016/j.ymthe.2006.08.637

565. Acceleration of Fracture Healing with Adenovirally Transduced Human BMP-2 and -6 Genes in Horse Metatarsal Osteotomy and Ostectomy Models

Akikazu Ishihara, Alicia L. Bertone, Alan L. Litsky, John S. Mattoon and Stephen E. Weisbrode

Mol Ther 13: S217-S218; doi:10.1016/j.ymthe.2006.08.638

566. Delaying the Onset of Diabetes in the NOD Mouse Using Exosomes Derived from Dendritic Cells Transfected with Adenoviral Vectors

Melanie A. Ruffner, Seon Hee Kim, Nicole R. Bianco, William J. Shufesky, Nick Giannoukakis, Adrian E. Morelli and Paul D. Robbins

Mol Ther 13: S218-S218; doi:10.1016/j.ymthe.2006.08.639

567. Adeno-Associated Virus Vector 8 (AAV8) Provides Efficient Gene Delivery to Skeletal Muscles In Utero by Systemic Adminstration

Bhanu Munil Koppanati, Juan Li, Bing Wang, Xiao Xiao and Paula Ruth Clemens

Mol Ther 13: S218-S218; doi:10.1016/j.ymthe.2006.08.640

568. Ex Vivo Mesenchymal Stem Cell Therapy with rAAV2 Encoding BMP-2 Enhances Bone Regeneration in Ovariectomized Mouse Model

Sanjay Kumar, Tim R. Nagy and Selvarangan Ponnazhagan

Mol Ther 13: S219-S219; doi:10.1016/j.ymthe.2006.08.641

569. Gene Therapy of Uterine Leiomyoma: Adenovirus-Mediated Herpes Simplex Virus Thymidine Kinase/Ganciclovir Treatment Inhibits Growth of Human and Rat Leiomyoma Cells In Vitro and in a Nude Mouse Model

Salama A. Salama, Marwa W. Kamel, Gregory M. Christman, Hui Q. Wang and Ayman A. Al-Hendy

Mol Ther 13: S219-S219; doi:10.1016/j.ymthe.2006.08.642

570. Ectopic Expression of Adenoviral Smad7 Significantly Reduces Hypertrophic Scarring in Rabbit Ears by Abrogating TGF|[beta]|1 Signalling

Juergen Kopp, Harun Seyhan, Katrin Messingschlager, Vanessa Pe|[ntilde]|a de Bender and Raymund E. Horch

Mol Ther 13: S219-S220; doi:10.1016/j.ymthe.2006.08.643

571. Increasing BMP Responsiveness in Human Mesenchymal Stem Cells In-Vitro by Delivery of the Osteoinductive LMP-1 Gene

Manjula Viggeswarapu, Maggie Bargouti, Mesfin Teklemariam, Chantrice Rogers, Liping Zhu, Nancy Baker, Louisa F. Titus and Scott D. Boden

Mol Ther 13: S220-S220; doi:10.1016/j.ymthe.2006.08.644

572. rAd-p21 To Reduce Excessive Dermal Scarring: Efficacy, Expression, and Tensile Strength in Animal Models

David W. Kang, Dan-Ling Gu, L. David Looper, Barry J. Sugarman, Erlinda M. Quijano and Monica L. Zepeda

Mol Ther 13: S220-S220; doi:10.1016/j.ymthe.2006.08.645

573. Enhanced Level of Gene Correction Mediated by Oligonucleotides Containing CpG Modification in the mdx Mouse Model for Duchenne Muscular Dystrophy

Carmen Bertoni, Arjun Rustagi and Thomas A. Rando

Mol Ther 13: S221-S221; doi:10.1016/j.ymthe.2006.08.646

574. Models of Cancer Cachexia: Treatment with Inhibition of NF-kB

Jad R. Maamary, Zhilong Jiang and Paula R. Clemens

Mol Ther 13: S221-S221; doi:10.1016/j.ymthe.2006.08.647

575. Correction of Ventilation in Glycogen Storage Disease Type II Mice after Gel-Mediated Delivery of Adeno-Associated Virus Serotype 1 Vectors

Cathryn Mah, Lara R. DeRuisseau, Christina A. Pacak, Melissa A. Lewis, David D. Fuller and Barry J. Byrne

Mol Ther 13: S221-S222; doi:10.1016/j.ymthe.2006.08.648

576. Hypoxic Adipocytes Support Early Heterotopic Bone Formation

Elizabeth A. Olmsted-Davis, Francis H. Gannon, Zbigniew Gugala, John A. Hipp, Christine Foultier-Dilling, Michael H. Heggeness and Alan R. Davis

Mol Ther 13: S222-S222; doi:10.1016/j.ymthe.2006.08.649

577. Inducible Regulation of Runx2-Stimulated Osteogenesis

Charles A. Gersbach, Joseph M. Le Doux, Robert E. Guldberg and Andres J. Garcia

Mol Ther 13: S222-S223; doi:10.1016/j.ymthe.2006.08.650

578. Suppression of Inflammation Following Intramuscular Administration of Pseudotyped AAV-TNFR:Fc Vectors in a Rat Model of Arthritis

Haim Burstein, Kurt Lustig and Ziv Sandalon

Mol Ther 13: S223-S223; doi:10.1016/j.ymthe.2006.08.651

579. Non-Invasive Measurement of Maximal Strength in the Normal and Dystrophic Dog Quadriceps Using Magnetic Stimulation of the Femoral Nerve

Frederick J. Balzer, Martin K. Childers, Janet R. Bogan, Daniel J. Bogan, Joe N. Kornegay and Hansell H. Stedman

Mol Ther 13: S223-S223; doi:10.1016/j.ymthe.2006.08.652

580. Gene Therapy of Chronic Hepatitis B Infection Using a High-Capacity Adenovirus Expressing Interleukin 12 under the Control of a Liver Specific Mifepristone-Inducible Promoter

Julien S. Crettaz, Pedro Berraondo, Laura Ochoa, Astrid Paneda, Itziar Otano, Cristina Olague, Africa Vales, Stefan Kochanek, Jesus Prieto and Gloria Gonzalez-Aseguinolaza

Mol Ther 13: S224-S224; doi:10.1016/j.ymthe.2006.08.654

581. IL-23 Is Required for B-Cell Memory after CD40 Ligand-Modified Dendritic Cell Vaccination

Mingquan Zheng, Jolia A. Bindas, Rekha Rapaka and Jay K. Kolls

Mol Ther 13: S224-S224; doi:10.1016/j.ymthe.2006.08.655

582. CNS Gene Delivery Targeting CCR3 Protects Brain Microglia from HIV-1

Lokesh Agrawal and David S. Strayer

Mol Ther 13: S224-S225; doi:10.1016/j.ymthe.2006.08.656

583. Evaluation of a pDNA-Based Anthrax Vaccine and Immune Correlates of Protection in Mice and Non-Human Primates

Peggy Lalor, Vanessa Whitlow, C. Richard Lyons, Julie Lovechik, Mark R. Perry, Jane Morrow, Peter Hobart, Holly Horton, Larry Smith, David Kaslow and Alain Rolland

Mol Ther 13: S225-S225; doi:10.1016/j.ymthe.2006.08.657

584. Enhanced Inhibition of HIV Using Combinatorial Genetic Therapy Against HIV-1 Integrase Delivered by SV40 Vectors

Elena I. Marusich and David S. Strayer

Mol Ther 13: S225-S225; doi:10.1016/j.ymthe.2006.08.658

585. Improved Efficacy of DNA Vaccines for HIV and Smallpox Using Constant-Current Electroporation

Lauren Hirao, Amir S. Khan, Ruxandra Draghia-Akli and David B. Weiner

Mol Ther 13: S226-S226; doi:10.1016/j.ymthe.2006.08.659

586. Anti-HIV-1 Neutralizing Antibody Gene Delivery to Rhesus Macaques and Rodents: A Novel Vaccination Approach

K. Reed Clark, Jianchao Zhang, David C. Montefiori and Philip R. Johnson5

Mol Ther 13: S226-S226; doi:10.1016/j.ymthe.2006.08.660

587. HIV-1 Glycoprotein gp120 Induces Apoptosis in the Caudate-Putamen In Vivo: Implications for Gene Transfer of Anti-Oxidant Enzymes Using SV40 Vectors

Jean-Pierre Louboutin, Lokesh Agrawal, Beverly A.S. Reyes, Elisabeth J. van Bockstaele and David S. Strayer

Mol Ther 13: S226-S227; doi:10.1016/j.ymthe.2006.08.661

588. Hepatic HB-EGF (Heparin-Binding EGF-Like Growth Factor) Gene Therapy for Fulminant Hepatic Failure in Mice: More Potent Protective and Mitogenic Effects for Hepatocytes Than HGF (Hepatocyte Growth Factor)

Ken-ichiro Kosai, Ngin Cin Khai and Tomoyuki Takahashi

Mol Ther 13: S227-S227; doi:10.1016/j.ymthe.2006.08.662

589. Repeated Recombinant Adenovirus (rAd) Administration To Generate Mucosal Antibodies (Abs) vs Botulinum Toxin A (BoNT/A)

Marlene S. Strayer, Andrew B. Maksymowych, Carmen N. Nichols, Steven Elek, Jean-Pierre Louboutin, Lance L. Simpson and David S. Strayer

Mol Ther 13: S227-S228; doi:10.1016/j.ymthe.2006.08.663

590. Recombinant Adenovirus Vaccines Against Anthrax

Michael J. McConnell and Michael J. Imperiale

Mol Ther 13: S228-S228; doi:10.1016/j.ymthe.2006.08.664

591. Development of Anti-JC Virus |[ldquo]|Designer T Cells|[rdquo]| for Progressive Multifocal Leukoencephalopathy (PML) Immunotherapy

Wen Yang, Esther Beaudoin, Renaud A. Du Pasquier, Igor J. Koralnik and Richard P. Junghans

Mol Ther 13: S228-S229; doi:10.1016/j.ymthe.2006.08.665

592. Effective Transduction of Nondividing PBL, Monocytes and Monocyte-Derived Macrophages with SV40-Derived Vectors Protects from HIV-1 Challenge

Elena I. Marusich and David S. Strayer

Mol Ther 13: S229-S229; doi:10.1016/j.ymthe.2006.08.666

593. Combination Anti-HIV-1 Gene Therapy Simultaneously Targeting CCR5 and Rev Protein Using SV40-Derived Vectors Inhibits Replication of HIV

Alena A. Chekmasova and David S. Strayer

Mol Ther 13: S229-S229; doi:10.1016/j.ymthe.2006.08.667

594. Protection Against In Vivo Tumor Growth after Electroporation-Enhanced DNA Vaccination with the Hepatitis C Virus Non-Structural 3/4A

Rune Kjeken, Gustaf Ahlen, Jonas Soderholm, Torunn Tjelle, Iacob Mathiesen and Matti Sallberg

Mol Ther 13: S229-S230; doi:10.1016/j.ymthe.2006.08.668

595. Nasal Delivery of Adenovirus Expressing the Ebola Glycoprotein Protects Mice Against Ebola Virus in the Presence of Preexisting Immunity to the Vaccine Carrier

Maria Croyle, Heinz Feldmann, Steven Jones, James M. Wilson and Gary P. Kobinger

Mol Ther 13: S230-S230; doi:10.1016/j.ymthe.2006.08.669

596. A Novel Replication Incompetent Human Subgroup D Adenoviral Vector Based on Type 49: Manufacture on PER.C6|[reg]|, Cell Tropism and Immunogenicity

Angelique Lemckert, Jos Grimbergen, Anna Thorner, Ronald Vogels, Paul Quax, Jaap Goudsmit, Dan Barouch and Menzo Havenga

Mol Ther 13: S230-S230; doi:10.1016/j.ymthe.2006.08.670

597. DNA Vaccines: Induction of Humoral and Cellular Responses Via Skin or Muscle Immunization Enhanced by Electroporation

Lei Zhang, Georg Widera, Susan Bleecher and Dietmar Rabussay

Mol Ther 13: S231-S231; doi:10.1016/j.ymthe.2006.08.671

598. Effective Humoral and Cellular Smallpox-Immune Responses Using a Combination of Plasmids Delivered by Intramuscular Injection Followed by Constant-Current Electroporation in Rabbits

Amir S. Khan, Lauren Hirao, David B. Weiner and Ruxandra Draghia-Akli

Mol Ther 13: S231-S231; doi:10.1016/j.ymthe.2006.08.672

599. Neuron Loss Mediated by HIV-1 gp120 In Vivo: Neuroprotection Using SV40 Gene Transfer of Antioxidant Enzymes

Jean-Pierre Louboutin, Lokesh Agrawal, Beverly A.S. Reyes, Elisabeth J. van Bockstaele and David S. Strayer

Mol Ther 13: S232-S232; doi:10.1016/j.ymthe.2006.08.673

600. Transduced Cells with Lentiviral Vector Expressing gp41-Derived c-Peptide Are Protected from HIV-1 Infection

Kwang-soo Ahn, Seok Kee Chang, Dokeun Kim, Won Shin and Yeowon Sohn

Mol Ther 13: S232-S232; doi:10.1016/j.ymthe.2006.08.674

601. Potential of Gene Transfer for HIV/AIDS Therapy: Overwhelming and Repeated HIV Challenge Selects for Transduced Lymphocytes Capable of Long-Term Survival and Enduring Resistance to HIV

Elena I. Marusich and David S. Strayer

Mol Ther 13: S232-S233; doi:10.1016/j.ymthe.2006.08.675

602. Effectiveness of Gene Delivery Targeting HIV-1 Integrase in Inhibiting HIV Integration: Lack of HIV-1 Genomes in T-Lymphocytes during Repeated Challenges with HIV-1

Elena I. Marusich, Christine B. Mitchell and David S. Strayer

Mol Ther 13: S233-S233; doi:10.1016/j.ymthe.2006.08.676

603. Withdrawn

Mol Ther 13: S233-S233; doi:10.1016/j.ymthe.2006.08.677

604. Comparative Analysis of Different Methods for Quantitative Evaluation of Neutralizing Antibody to Ebola Virus in a Biosafety Level 2 or 4 Environment

Hideki Ebihara, Xiangguo Qiu, Steven Theriault, Matthew Klassen, Ute Stroeher, Jim Strong, Steven Jones, James M. Wilson, Heinz Feldmann and Gary Kobinger

Mol Ther 13: S233-S234; doi:10.1016/j.ymthe.2006.08.678

605. Long-Term Protection Afforded by a Single Administration of an Ad-Based Anti-Y. pestis Vaccine Against a Lethal Respiratory Challenge with Y. pestis

Maria J. Chiuchiolo, Anja Krause, Ronald G. Crystal and Julie L. Boyer

Mol Ther 13: S234-S234; doi:10.1016/j.ymthe.2006.08.679

606. Identification of a 45-aa Domain of the F12-Vif Mutant Possessing Anti-HIV Activity

Simona Porcellini, Rossella Lupo, Giuliana Vallanti, Maurizio Federico, Fulvio Mavilio and Chiara Bovolenta

Mol Ther 13: S234-S234; doi:10.1016/j.ymthe.2006.08.680

607. Novel Adeno-Associated Viruses as Vaccine Carriers for HIV-1: Evaluation in Non-Human Primates

Roberto Calcedo, Yan Zhi, Joanita M. Figueredo, Judith I. Franco, Julie C. Johnston, Rebecca L. Grant and James M. Wilson

Mol Ther 13: S234-S235; doi:10.1016/j.ymthe.2006.08.681

608. Dose Escalation of Recombinant Adenovirus-Based Influenza Virus Vaccine Encoding the Full Length Hemagglutinin (HA) of the A/Vietnam/1203/2004 (H5N1) To Immunize Na|[iuml]|ve and Ad-Immune Mice

Julia Steitz, Wentao Gao, Edward Nwanegbo, Ruben O. Donis, Jacqueline M. Katz and Andrea Gambotto

Mol Ther 13: S235-S235; doi:10.1016/j.ymthe.2006.08.682

609. Acute-Phase Toxicity Following Systemic Administration of Non-Human Primate Derived Adenoviral Vectors to Mice

Suryanarayan Somanthan, Zhe Zhang, Guang-Ping Gao, Martin W. Lock, Peter L. Bell, Soumitra Roy, Arbansjit K. Sandhi and James M. Wilson

Mol Ther 13: S235-S235; doi:10.1016/j.ymthe.2006.08.683

610. The Effect of In Vitro Antiviral Therapy on Lentiviral Transduction

Priscilla Yam, Paola Marcovecchio, Shirley Li, Jiing-Kuan Yee and John A. Zaia

Mol Ther 13: S235-S236; doi:10.1016/j.ymthe.2006.08.684

611. Induction of Persistent Passive Immunity Against Anthrax Toxin by an Adeno-Associated Virus Type rh10 Vector Expressing Anti-Protective Antigen Antibody

Bishnu P. De, Neil R. Hackett, Jian Ping Qiu, Julie L. Boyer, James M. Wilson and Ronald G. Crystal

Mol Ther 13: S236-S236; doi:10.1016/j.ymthe.2006.08.685

612. Withdrawn

Mol Ther 13: S236-S236; doi:10.1016/j.ymthe.2006.08.687

613. Challenging an Old Drug in a New Context: Low-Dose Cyclophosphamide in Immunogenetherapy of Cancer

Sebastian Tuve, Shaoheng Ni and Andre Lieber

Mol Ther 13: S236-S237; doi:10.1016/j.ymthe.2006.08.688

614. The Role of the Activated MAPK Pathway through the Oncogenic BRAFV600E-Mutation in the Immune Escaping Mechanism of Melanoma

Hidetoshi Sumimoto and Yutaka Kawakami

Mol Ther 13: S237-S237; doi:10.1016/j.ymthe.2006.08.689

615. Anti-Tumor Activities of IL-12 and IL-23 Are Mediated by Similar, yet Divergent, Effector Mechanisms

JaNean C. Ceidro, Euan Lockhart, Seon-Hee Kim and Paul D. Robbins

Mol Ther 13: S237-S237; doi:10.1016/j.ymthe.2006.08.690

616. Enhancement of Antitumor Activity of Interferons by RNAi-Mediated Silencing of SOCS Genes in Tumor Cells

Yuki Takahashi, Haruka Kaneda, Makiya Nishikawa and Yoshinobu Takakura

Mol Ther 13: S237-S238; doi:10.1016/j.ymthe.2006.08.691

617. Tumor Lysates Prepared from Cells Infected with a Fusogenic Oncolytic HSV Stimulates Potent Antitumor Immunity Against Primary and Metastatic Murine Mammary Carcinoma

Xinping Fu, Lihua Tao and Xiaoliu Zhang

Mol Ther 13: S238-S238; doi:10.1016/j.ymthe.2006.08.692

618. Hydrodynamic Limb Vein-Delivered Xenogeneic Plasmid DNA Cancer Vaccine Effectively Induces Antitumor Protection

Zane C. Neal, Mary Kay Bates and Hans Herweijer

Mol Ther 13: S238-S238; doi:10.1016/j.ymthe.2006.08.693

619. Tumor-Derived Chemokine MCP-1/CCL2 Is Sufficient for Mediating Tumor Tropism of Adoptively Transferred T-Cells

Christine E. Brown, Reena Vishwanath, Brenda Aguilar, WenChung Chang and Michael C. Jensen

Mol Ther 13: S239-S239; doi:10.1016/j.ymthe.2006.08.694

620. Liposome-Based Therapeutic Vaccine for Cervical Cancer

Weihsu Claire Chen and Leaf Huang

Mol Ther 13: S239-S239; doi:10.1016/j.ymthe.2006.08.695

621. Immunological Memory in a Syngeneic Model of Recurrent and Multifocal Glioblastoma

Gwendalyn D. King, James F. Curtin, Chunyan Liu, Catherine Bresee, Sarah B. Honig, Jeffery M. Zirger, Nico VanRooijen, Antoni Ribas, Robert Pechnick, Pedro R. Lowenstein and Maria G. Castro

Mol Ther 13: S239-S239; doi:10.1016/j.ymthe.2006.08.696

622. Effective Prevention of Spontaneous Lung Metastasis of AT6.3 Prostate Cancer by Intravenous Administration of Dendritic Cells Activated by Non-Transmissible Sendai Virus

Tomonori Kato, Yasuji Ueda, Yasuo Yoneyama, Akinao Matsunaga, Megumi Akizawa, Akira Komiya, Hiroyoshi Suzuki, Makoto Inoue, Mamoru Hasegawa, Tomohiko Ichikawa and Yoshikazu Yonemitsu

Mol Ther 13: S240-S240; doi:10.1016/j.ymthe.2006.08.697

623. Polymer Microparticles Delivering a Idiotype/Chemokine Fusion DNA Vaccine Generate Protective Immunity in a Mice Model of B Cell Lymphoma

Sudhir P. Kasturi, Bilal Ghosn, Kassandra S. Thomson, Hong Qin, Larry Kwak and Krishnendu Roy

Mol Ther 13: S240-S240; doi:10.1016/j.ymthe.2006.08.698

624. Conditionally Replicative Adenovirus Vector Overexpressing the ADP (E3-11.6K) Protein and Armed with Human Interferon Alpha

Elena V. Shashkova, Jacqueline F. Spencer, William S.M. Wold and Konstantin Doronin

Mol Ther 13: S240-S241; doi:10.1016/j.ymthe.2006.08.699

625. Viral Shedding after Intratumoral Injection of Adenoviral Vectors to Patients with Cancer

Gloria Gonz|[aacute]|lez-Aseguinolaza, Maria Ruiz, Cristina Olag|[uuml]|e, Jesus Prieto, Juan Ruiz and Bruno Sangro

Mol Ther 13: S241-S241; doi:10.1016/j.ymthe.2006.08.700

626. Inactivated Sendai Virus Particle (HVJ-E) Solely Induces Specific Anti-Tumor Immune Response and Eradicates Murine Carcinoma