TABLE OF CONTENTS
Volume 13, Issue S1 (May 2006)
Abstracts |
Abstracts |
Abstracts |
Abstracts |
Abstracts |
Author Index |
Keyword Index
Abstracts
1. Species Choice for Animal Modeling Cystic Fibrosis and Gene Therapy to the Airway
Xiaoming Liu, Ziying Yan, Meihui Luo, Liang N. Zhang, Cyndi Trygg, Carolina Smith, Keith Munson, William Guggino, Bruce Bunnell and John F. Engelhardt
Mol Ther 13: S1-S1; doi:10.1016/j.ymthe.2006.08.011
2. Identification of Different Modes of Viral Transport in the Non-Human Primate Brain after Convection-Enhanced Delivery of AAV Serotype Vectors
Marco A. Passini, Jie Bu, James C. Dodge, Lamya S. Shihabuddin, Tatyana V. Taksir, Denise A. Griffiths, John Bringas, Piotr Hadaczek, Mihaela Avramut, Seng H. Cheng and Krystof Bankiewicz
Mol Ther 13: S1-S1; doi:10.1016/j.ymthe.2006.08.012
3. Adeno-Associated Virus 2-Mediated Gene Transfer: Identification of a Cellular Protein Serine/Threonine Phosphatase Involved in Augmenting Vector Transduction Efficiency
Weihong Zhao, Jianqing Wu,, Li Zhong and Arun Srivastava
Mol Ther 13: S1-S2; doi:10.1016/j.ymthe.2006.08.013
4. Role of Notch1 in Augmenting Intracellular Trafficking and Transgene Expression of Recombinant Adeno-Associated Virus-2
Changchun Ren, April F. White and Selvarangan Ponnazhagan
Mol Ther 13: S2-S2; doi:10.1016/j.ymthe.2006.08.014
5. Mechanisms for Hairpin Loop Opening of |[ldquo]|Closed|[rdquo]| AAV-ITRs by Specific Cellular Endonuclease Activities, a Prerequisite for rAAV Vector Genome Recombinations In Vivo
Katsuya Inagaki, Theresa A. Storm, Mark A. Kay and Hiroyuki Nakai
Mol Ther 13: S2-S3; doi:10.1016/j.ymthe.2006.08.015
6. AAV8-Mediated Transgene Expression in Mice and Non-Human Primates
Hiroaki Mizukami, Jun Mimuro, Akira Ishiwata, Fumiko Ono, Takashi Matsushita, Takashi Okada, Masashi Urabe, Akihiro Kume, Keiji Terao, Yoichi Sakata and Keiya Ozawa
Mol Ther 13: S3-S3; doi:10.1016/j.ymthe.2006.08.016
7. Adeno-Associated Virus Type 2 (AAV2) Contains an Integrin alpha5beta1 Recognition Sequence Essential for Viral Cell Entry
Aravind Asokan, Julie B. Hamra, Mavis Agbandje-McKenna and Richard J. Samulski
Mol Ther 13: S3-S3; doi:10.1016/j.ymthe.2006.08.017
8. Adeno-Associated Virus 2-Mediated Gene Transfer: A Complex Interaction between Epidermal Growth Factor Receptor Protein Tyrosine Kinase Signaling and Ubiquitin/Proteasome Pathway in Transgene Expression
Li Zhong, Weihong Zhao, Jianqing Wu, Baozheng Li and Arun Srivastava
Mol Ther 13: S3-S4; doi:10.1016/j.ymthe.2006.08.018
9. Biology of rAAV8 in Mouse Liver Following Vector Administration at Birth
Katsuya Inagaki, Sally Fuess, Theresa A. Storm, Mark A. Kay and Hiroyuki Nakai
Mol Ther 13: S4-S4; doi:10.1016/j.ymthe.2006.08.019
10. Adeno-Associated Virus Type-1 Vectors Transduce Human Polarized Airway Epithelia without Polarity Preference
Ziying Yan, Diana C.M. Lei-Butters, Xiaoming Liu, Yulong Zhang, Meihui Luo, Liang Zhang, Roman Zak and John F. Engelhardt
Mol Ther 13: S4-S5; doi:10.1016/j.ymthe.2006.08.020
11. Transposition from a Gene-Deleted Adenoviral Vector Results in Phenotypic Correction in a Canine Model for Hemophilia B
Anja Ehrhardt, Hui Xu, Aaron M. Dillow, Stephen R. Yant, Timothy C. Nichols and Mark A. Kay
Mol Ther 13: S5-S5; doi:10.1016/j.ymthe.2006.08.022
12. Therapeutic Potential of the Chimeric Adenovirus 5/40 as Vector for Intestine-Directed Gene Therapy
Ester Rodriguez, Carolina Romero, Mireia Ferrer, Joan F. Burgue|[ntilde]|o, Ester Fernandez, Estel Gil, Hirofumi Hamada, Assumpcio Bosch and Miguel Chillon
Mol Ther 13: S5-S5; doi:10.1016/j.ymthe.2006.08.023
13. In Vivo Stable Transduction of Humanized Liver Tissue in Chimeric Mice Via High-Capacity Adenovirus-Lentivirus Hybrid Vector
Shuji Kubo, Miho Kataoka, Chise Tateno, Donna J. Palmer, Philip Ng, Katsutoshi Yoshizato and Noriyuki Kasahara
Mol Ther 13: S6-S6; doi:10.1016/j.ymthe.2006.08.024
14. High Efficiency and Long-Term Persistence In Vivo from a Helper Dependent Adenovirus/Epstein-Barr Virus Hybrid Vector
Sean D. Gallaher, Jose S. Gil and Arnold J. Berk
Mol Ther 13: S6-S6; doi:10.1016/j.ymthe.2006.08.025
15. Genetically Targeted Adenovirus Vector Carrying Reovirus |[sigma]|1-Based Attachment Protein for Improved Systemic Gene Delivery
Frederik H.E. Schagen, Harm C.A. Graat, Jan E. Carette, Terence S. Dermody, Michael A. vanGeer and Victor W. van Beusechem
Mol Ther 13: S6-S7; doi:10.1016/j.ymthe.2006.08.026
16. Direct Selection of Targeted Vector from a Random Peptide Library Displayed on Adenoviral Fiber Knob
Kazunori Aoki, Yoshiaki Miura, Kimiko Yoshida, Kazuteru Hatanaka, Takeshi Nishimoto, Shumpei Ohnami, Joanne T. Douglas, David T. Curiel and Teruhiko Yoshida
Mol Ther 13: S7-S7; doi:10.1016/j.ymthe.2006.08.027
17. Biodistribution, Innate Immune Response and Toxicity Following Intravenous Inoculation of Mice with Nonhuman Adenoviral Vectors
Dinesh S. Bangari, Anurag Sharma, Aseem Pandey, Harm HogenEsch and Suresh K. Mittal
Mol Ther 13: S7-S7; doi:10.1016/j.ymthe.2006.08.028
18. Comparison of Antitumor Activity of Cytosine Deaminase::Uracil Phosphoribosyl Transferase (CD::UPRT) and Purine Nucleoside Phosphorylase (PNP) Suicide Genes Using Replicative but Non-Disseminative Adenovirus Vectors
Jairo Jaime, Nadine Jabbour, William Parker, Eric Sorscher, Josephine Nalbantoglu and Bernard Massie
Mol Ther 13: S8-S8; doi:10.1016/j.ymthe.2006.08.029
19. A New, Plasmid-Based Adenoviral Vectoring System Derived from the Highly Immunogenic, Human Ad4 Strain
Zachary C. Hartman, Todd Mendelson and Andrea Amalfitano
Mol Ther 13: S8-S8; doi:10.1016/j.ymthe.2006.08.030
20. Construction and Characterization of Adenovirus Vectors Expressing Optimized Blood Stage Antigens of Plasmodium falciparum
Ping Chen, Svetlana Konovalova, Keith Limbach, Maureen E. Stefaniak, Noelle B. Patterson, Joseph J. Campo, Sheng Li, Richter King, Denise L. Doolan and Joseph T. Bruder
Mol Ther 13: S8-S9; doi:10.1016/j.ymthe.2006.08.031
21. Peptide-Targeted Ad19p-Based Adenoviral Vectors for Renal Gene Delivery
Laura Denby, Lorraine M. Work, Dan J. Von Seggern, Eugene Wu, Ela Hunt, Stuart A. Nicklin and Andrew H. Baker
Mol Ther 13: S9-S9; doi:10.1016/j.ymthe.2006.08.034
22. Creation of a Biological Pacemaker by Cell Fusion
Hee Cheol Cho, Yuji Kashiwakura and Eduardo Marb|[aacute]|n
Mol Ther 13: S9-S10; doi:10.1016/j.ymthe.2006.08.033
23. Catheter-Mediated Local Intramural Delivery of AdEC-SOD Inhibits Oxidative Stress and Reduces In-Stent Neointima by Accelerating Endothelial Cell Recovery in WHHL Rabbits Displaying Complex Human-Like Atherosclerotic Lesions
Olli Leppanen, Jan Hinrich Brasen, Tommi Heikura, Matias Inkala, Fabian Ahrens, Juha Rutanen, Anna-Liisa Levonen, Samar Basu, Mikko O. Laukkanen and Seppo Yla-Herttuala
Mol Ther 13: S10-S10; doi:10.1016/j.ymthe.2006.08.035
24. Widespread and Efficient Gene Delivery to the Heart and Liver Using AAV Serotype 9: Implications for Cardiovascular Disease and Hemophilia
Thierry VandenDriessche, Lieven Thorrez, Abel Acosta-Sanchez, Lilly Wang, Veerle Gillijns, Ma Ling, Herman Vandenburgh, Nico Mertens, Nico Callewaert, James Wilson, Desire Collen and Marinee Chuah
Mol Ther 13: S10-S11; doi:10.1016/j.ymthe.2006.08.036
25. Development and Characterization of Viral Vectors with High Specificity for Atherosclerotic Plaques
Katie M. White, Hildergard Buening, Lorraine M. Work, Michael Hallek, Stuart A. Nicklin and Andrew H. Baker
Mol Ther 13: S11-S11; doi:10.1016/j.ymthe.2006.08.037
26. Lentiviral Vector Delivery of vMIP-II Using Both Transplanted Endothelial and Progenitor Cells Enhances a Robust and Functional Angiogenesis In Vivo
Stephanie Cherqui, Camille Thorpe, Sunil M. Kurian and Daniel R. Salomon
Mol Ther 13: S11-S11; doi:10.1016/j.ymthe.2006.08.038
27. Prevention of Cardiac Remodeling and Heart Failure in Dahl-Salt Sensitive Rats by AAV Vector-Mediated Interleukin-10 Expression
Mutsuko Sarukawa, Takashi Okada, Toru Yoshioka, Takayuki Ito, Tatsuya Nomoto, Hiroaki Mizukami, Akihiro Kume, Keiji Yamamoto, Uichi Ikeda, Kazuyuki Shimada and Keiya Ozawa
Mol Ther 13: S12-S12; doi:10.1016/j.ymthe.2006.08.039
28. rAAV2/9 Mediated Gene Delivery of Acid |[alpha]|-Glucosidase Corrects the Cardiac Phenotype in a Mouse Model of Pompe Disease
Christina A. Pacak, Cathryn Mah, Kerry O. Cresawn, Melissa A. Lewis, Sean Germain and Barry J. Byrne
Mol Ther 13: S12-S12; doi:10.1016/j.ymthe.2006.08.040
29. Effect of AAV6-Mediated TIMP-2 Overexpression in a Murine Model of Heart Failure
Satsuki Mori, Xiaodong Zhu, Gregory Gibson, Benjamin Burkhead and Charles F. McTiernan
Mol Ther 13: S13-S13; doi:10.1016/j.ymthe.2006.08.041
30. Cardiac-Specific Gene Expression Using Pseudotyped AAV Vectors and the Cardiac Troponin-T Promoter
Konkal-Matt R. Prasad, Zequan Yang, Yaqin Xu, Stuart S. Berr and Brent A. French
Mol Ther 13: S13-S13; doi:10.1016/j.ymthe.2006.08.042
31. Dystrophin Expression in Muscles of Duchenne Muscular Dystrophy Patients Following High-Density Injections of Normal Myogenic Cells
Jacques P. Tremblay, Daniel Skuk, Marlyne Goulet, Brigitte Roy, Pierre Chapdelaine, Raynald Roy, Francine Dugr|[eacute]|, Jean-Pierre Bouchard, Jean-Guy Lachance, Michel Sylvain, Louise Desch|[ecirc]|nes and H|[eacute]|l|[egrave]|ne Senay
Mol Ther 13: S13-S14; doi:10.1016/j.ymthe.2006.08.044
32. Improvement of Muscle Mass Using shRNA Targeting Myostatin or Activin Receptor IIb
Julie Dumonceaux, Solenne Marie and Luis Garcia
Mol Ther 13: S14-S14; doi:10.1016/j.ymthe.2006.08.045
33. Systemic Delivery of AAV8/DC190-GAA to Pompe Mice Normalizes Muscle Pathology and Corrects Motor Function Deficits
R.J. Ziegler, M.A. Zhao, S.D. Bercury, J.A. Fidler, J.W. Foley, D. Armentano, S. Ryan, T. Taksir, D. Griffiths, L.S. Shihabuddin, R.K. Scheule and S.H. Cheng
Mol Ther 13: S14-S14; doi:10.1016/j.ymthe.2006.08.046
34. Phi C31 Integrase System Enhances Dystrophin Gene Expression in Skeletal Muscle of Mouse Models for Duchenne Muscular Dystrophy
Carmen Bertoni, Sohail Jarrahian, Thurman M. Wheeler, Yining Li, Eric C. Olivares, Michele P. Calos and Thomas A. Rando
Mol Ther 13: S14-S15; doi:10.1016/j.ymthe.2006.08.047
35. Systemic Administration of rAAV6-Microdystrophin Preserves Muscle Function and Extends Lifespan in the Dystrophin-/Utrophin- Mouse Model of Severe Muscular Dystrophy
Paul Gregorevic, Michael J. Blankinship, Elina Minami, James M. Allen, Charles E. Murry and Jeffrey S. Chamberlain
Mol Ther 13: S15-S15; doi:10.1016/j.ymthe.2006.08.048
36. Transplantation of SM/C-2.6+ Satellite Cells Transduced with Micro-Dystrophin CS1 cDNA by Lentiviral Vector into mdx Mice
Madoka Ikemoto, So-ichiro Fukada, Akiyoshi Uezumi, Satoru Masuda, Ampong Beryl Nyamekye, Hiroyuki Miyoshi, Hiroshi Yamamoto, Yuko Miyagoe-Suzuki and Shin'ichi Takeda
Mol Ther 13: S15-S15; doi:10.1016/j.ymthe.2006.08.049
37. Long-Term Expression of Mini-Human Dystrophin in Transgenic mdx Mice Improves Dystrophic Muscle Functions
Bing Wang, Juan Li, Chunlian Chen, Xiancheng Jiang, Terry O'Day, Jon Watchko and Xiao Xiao
Mol Ther 13: S16-S16; doi:10.1016/j.ymthe.2006.08.050
38. Morpholino Antisense Oligonucleotide Induced Exon Skipping Efficiently Restores Dystrophin Expression in the mdx Mouse
Dominic J. Wells, Caroline McCulley, Anna Graham, Ke Liu and Kim E. Wells
Mol Ther 13: S16-S16; doi:10.1016/j.ymthe.2006.08.051
39. Evaluation of rAAV-1 vs rAAV-8 Vectors and Their Mode of Delivery in Nonhuman Primate Skeletal Muscle
Alice Toromanoff, Yan Cherel, Jack-Yves Deschamps, Valder R. Arruda, Katherine A. High, Hansell H. Stedman, Mark E. Haskins, Fabienne Rolling, Ignacio Anegon, Philippe Moullier and Caroline Le Guiner
Mol Ther 13: S16-S17; doi:10.1016/j.ymthe.2006.08.052
40. Increased Transgene Expression of Dystrophin in mdx Muscle by RNAi-Mediated Silencing of Calpain Expression
Makiya Nishikawa, Kazuhiro Hirata, Kazuya Machida, Yuki Takahashi, Katsutoshi Yuasa, Shin'ichi Takeda and Yoshinobu Takakura
Mol Ther 13: S17-S17; doi:10.1016/j.ymthe.2006.08.053
41. Evaluation of Lung Cancer Virotherapy with Oncolytic Semliki Forest Virus Using Immunodeficient Rodent Tumor Model
Ann-Marie M|[auml]||[auml]|tt|[auml]|, Tiina Wahlfors, Katja H|[auml]|kkinen, Linda Jansson, Markus V|[auml]|h|[auml]|-Koskela, Ari Hinkkanen, Kimmo M|[auml]|kinen and Jarmo Wahlfors
Mol Ther 13: S17-S17; doi:10.1016/j.ymthe.2006.08.055
42. Resistance of Primary Ovarian Cancer Cells to Viral Oncolysis
Robert Strauss, Pavel Sova, Ying Liu, Zong Yi Li, Nicole Urban, Charles Drescher, Nancy Kiviat and Andre Lieber
Mol Ther 13: S18-S18; doi:10.1016/j.ymthe.2006.08.056
43. Long-Term T Cell Activation Following Combined In Situ Gene Therapy and Intensity-Modulated Radiotherapy Compared to Gene Therapy as Mono-Therapy in Prostate Cancer Patients
Tetsuo Fujita, Bin S. Teh, Terry L. Timme, Wei-Yuan Mai, Takefumi Satoh, Nobuyuki Kusaka, Koji Naruishi, Elmoataz Abdelfattah, Estuardo Aguilar-Cordova, Brian J. Miles, E. Brian Butler and Timothy C. Thompson
Mol Ther 13: S18-S18; doi:10.1016/j.ymthe.2006.08.057
44. Combination of Oncolytic Measles Virus Strains and Radiation Therapy Has Synergistic Activity in the Treatment of Glioblastoma Multiforme
Chunsheng Liu, Jann N. Sarkaria, Cory Allen, Paula J. Zollman, C. David James, Stephen J. Russell and Evanthia Galanis
Mol Ther 13: S19-S19; doi:10.1016/j.ymthe.2006.08.058
45. Paclitaxel-TRAIL Enhances the Distribution of Oncolytic Herpes Simplex Virus-1 in a Human Mammary Carcinoma Xenograft
Satoshi Nagano, Jean Y. Perentes, Rakesh K. Jain and Yves Boucher
Mol Ther 13: S19-S19; doi:10.1016/j.ymthe.2006.08.059
46. Phase I/II Study of Adenoviral Vector Delivery of HSV-tk Gene and the Intravenous Administration of Ganciclovir in Men with Local Recurrence of Prostate Cancer after Hormonal Therapy
Yasutomo Nasu, Haruki Kaku, Shin Ebara, Takashi Saika, Hiromi Kumon and Timothy C. Thompson
Mol Ther 13: S19-S20; doi:10.1016/j.ymthe.2006.08.060
47. A Combination Therapy of Selective Intraarterial Gendicine Infusion with Chemotherapy for Locally Advanced Head and Neck Carcinoma
Longjiang Li, Yuanding Huang, Lijuan Wang, Yi Li, Yuming Wen and Bo Han
Mol Ther 13: S20-S20; doi:10.1016/j.ymthe.2006.08.061
48. Adeno-Associated Viral (AAV) Vector- Mediated Systemic Delivery of mda-7/IL24 Inhibits Tumor Growth by Antitumor Bystander Effect
Ichiro Tahara, Koichi Miyake, Toshiyuki Kurai, Yukihiko Hirai, Eiji Uchida, Takashi Tajiri and Takashi Shimada
Mol Ther 13: S20-S20; doi:10.1016/j.ymthe.2006.08.062
49. Inhibition of Acid Ceramidase Expression by Small Interfering RNA Sensitize Human Prostae Cancer Cells to Apoptin Induced Cell Death
Xiang Liu, Guiwen Guo, Saeed N. Elojeimy, David H. Holman, Ayman Mahdy, Alicja Bielawska, Jacek Bielawski, Seymon Rubinchik, Jian-yun Dong, Thomas Keane, Mahvash Tavassoli, Yusuf A. Hannun and James N. Norris
Mol Ther 13: S21-S21; doi:10.1016/j.ymthe.2006.08.063
50. Adenoviral-Mediated Gene Transfer of Single Chain Fv 425:sTRAIL Fusion Protein Induces Target Cell Restricted Apoptosis in EGFR- Positive Tumor Cells and a Potent Bystander Effect
Hidde J. Haisma, Marike Dijkstra, Edwin Bremer and Wijnand Helfrich
Mol Ther 13: S21-S21; doi:10.1016/j.ymthe.2006.08.064
51. Clinical Study of Personalized Therapeutics Based on Genomic/Proteomic Profiling
John Nemunaitis, Neil Senzer, Jerry Shen, Phillip Maples, Donald Rao, Alex Tong, Padmasini Kumar, Joe Kuhn, Yu-An Zhang, Jian Liao, Iya Khalil, Colin Hill and Adi Gazdar
Mol Ther 13: S21-S22; doi:10.1016/j.ymthe.2006.08.066
52. A Phase 1 Dose-Escalation Trial of Intravesical CG0070 for Superficial Transitional Cell Carcinoma (TCC) of the Bladder after Bacillus Calmette-Guerin (BCG) Failure
Neil Senzer, John Nemunaitis, Michael Goldstein, James Arseneau, Don Lamm, Joe Stephenson, Harry Tsai, Kristina Neal, Junko Aimi, D.C. Yu, Daniel Maslyar, John Corman, James Mckiernan and James Burke
Mol Ther 13: S22-S22; doi:10.1016/j.ymthe.2006.08.067
53. Preliminary Results of a Pilot Phase I Clinical Trial of Adoptive Immunotherapy for B Cell Lymphoma Using CD8+ T Cells Genetically Modified To Express a Chimeric T Cell Receptor Recognizing CD20
Oliver W. Press, Jinjuan Wang, Catherine G. Lindgren, Eric Y. Chen, Ajay K. Gopal, John M. Pagel, Xiaojun Qian, Stanley R. Riddell, Philip D. Greenberg, Andrew Raubitschek and Michael C. Jensen
Mol Ther 13: S22-S23; doi:10.1016/j.ymthe.2006.08.068
54. TNFerade|[trade]| in Pancreas Cancer: Local Activation with Systemic Potential
Neil Senzer, John Nemunaitis, J. Macko and Thomas Davis
Mol Ther 13: S23-S23; doi:10.1016/j.ymthe.2006.08.069
55. Translating Preclinical Results into the Clinical Development of PV701, an Oncolytic Virus
Robert M. Lorence, M. Scot Roberts, James D. O'Neil, Pete T. Buasen, Li Zhang, William S. Groene and Michael K. Bamat
Mol Ther 13: S23-S23; doi:10.1016/j.ymthe.2006.08.070
56. The Efficacy of Replicating Virotherapy for Tumors Involves a Complex Equilibrium between Virus, Tumor and the Immune System
Rosa Maria Diaz, Feorilo Galivo, Jian Qiao, Jill Thompson, Timothy Kottke, John Bell, Glen Barber and Richard Vile
Mol Ther 13: S24-S24; doi:10.1016/j.ymthe.2006.08.071
57. Targeted Gene Delivery of Alpha-Interferon by Genetically Modified Hematopoietic Cells Inhibits Glioma Vascularization and Growth without Systemic Toxicity
Michele DePalma, Rossella Galli, Mary Anna Venneri, Letterio S. Politi, Ferdinando Pucci, Lucia Sergi Sergi, Elena Binda, Ehud Hauben and Luigi Naldini
Mol Ther 13: S24-S24; doi:10.1016/j.ymthe.2006.08.072
58. Oncolytic Measles Virus Delivery by Infected Cell Carriers |[ndash]| A Strategy To |[ldquo]|By-Pass|[rdquo]| the Pre-Existing Humoral Immune Response
Ianko D. Iankov, Boris R.A. Blechacz, Guy E. Griesmann, Mark J. Federspiel and Stephen J. Russell
Mol Ther 13: S24-S25; doi:10.1016/j.ymthe.2006.08.073
59. Targeted Gene Therapy of Malignant Glioma with Adult Stem Cells
Hrvoje Miletic, Yvonne Fischer, Tsanan Giroglou, Sara Litwak, Sandra Winkeler, Uwe Himmelreich, Werner Stenzel, Martina Deckert, Andreas H. Jacobs, Harald Neumann and Dorothee von Laer
Mol Ther 13: S25-S25; doi:10.1016/j.ymthe.2006.08.074
60. Radiation Improves Local Delivery of a Virus-Mimicking Nanostructure Complex in Tumors
Rebecca A. Abela, Liang Xu, Theodore S. Lawrence and Ming Zhang
Mol Ther 13: S25-S25; doi:10.1016/j.ymthe.2006.08.075
61. Successful Gene Therapy of a Mouse Model of Congenital Erythropoietic Porphyria with an Erythroid-Specific Lentiviral Vector
Elodie Robert, Magalie Lalanne, Isabelle Lamrissi-Garcia, Muriel Cario-Andre, Cecile Ged, Hubert De Verneuil and Francois Moreau-Gaudry
Mol Ther 13: S25-S26; doi:10.1016/j.ymthe.2006.08.077
62. Proteasome Activity Restricts Lentiviral Gene Transfer into Hematopoietic Stem Cells and Is Down-Regulated by Cytokines That Enhance Transduction
Francesca R. Santoni de Sio, Paolo Cascio, Anna Zingale, Mauro Gasparini and Luigi Naldini
Mol Ther 13: S26-S26; doi:10.1016/j.ymthe.2006.08.078
63. Long-Term Constitutive Expression of the Therapeutic Gene, IL2RG, Causes T-Cell Lymphomas in a Gene Therapy Model for XSCID
Niels-Bjarne Woods, Virginie Bottero, Manfred Schmidt, Christof von Kalle and Inder M. Verma
Mol Ther 13: S26-S27; doi:10.1016/j.ymthe.2006.08.079
64. Rescue of B Cell Development in an Animal Model of X-Linked Agammaglobulinemia (XLA) Via B Lineage-Specific Lentiviral Gene Therapy
Wenying Zhang, Stephanie Humblet-Baron, Kevin Kipp, Socheath Khim, Jordan Jarjour, Karen Sommer, Brigid Stirling, Lia Pernell and David J. Rawlings
Mol Ther 13: S27-S27; doi:10.1016/j.ymthe.2006.08.080
65. Long-Term Effects of Hematopoietic Stem Cell Gene Therapy in the Murine Model of Wiskott-Aldrich Syndrome: Persistence of Functional Correction of T Cells and Lack of Malignant Trasformation
Francesco Marangoni, Lo|[iuml]|c Dupr|[eacute]|, Samantha Scaramuzza, Cristina Panaroni, Sara Trifari, Raisa Jofra Hern|[aacute]|ndez, Adrian J. Thrasher, Anne Galy, Alessandro Aiuti, Luigi Naldini and Maria Grazia Roncarolo
Mol Ther 13: S27-S28; doi:10.1016/j.ymthe.2006.08.081
66. Gene Transfer-Mediated Expression of Murine Factor VIIa Improves Clot Formation in a Mouse Model for Bernard-Soulier Syndrome
Majed N. Aljamali, Paris Margaritis, Valder R. Arruda, Alex Schlachterman, Danielle Dunn, Jerry Ware and Katherine A. High
Mol Ther 13: S28-S28; doi:10.1016/j.ymthe.2006.08.082
67. The Chicken Hypersensitive Site (cHS4) Insulator Element Reduces Position Effects Thereby Increasing Expression from Globin Lentiviral Vectors
Paritha I. Arumugam, Jessica Scholes, Ping Xia, Natalya Perelman, Alexander Zarzuela, Jiing-Kuan Yee and Punam Malik
Mol Ther 13: S28-S28; doi:10.1016/j.ymthe.2006.08.083
68. Evidence for Correction of Mutations in the c-Kit Gene by rAAV Mediated Gene Targeting in W/Wv Mice
Arthur W. Nienhuis, John T. Gray, Serena Vayda, Amanda Cline, Marguerite V. Evans-Galea and David M. Bodine
Mol Ther 13: S29-S29; doi:10.1016/j.ymthe.2006.08.084
69. Selection of Hematopoietic Progenitor and Stem Cells in Transplanted Rhesus Macaques Using MGMT and HOXB4 Lentiviral Vectors
Yan Shou, John Gray, Brian Agricola, Zhijun Ma, Geeta K. Nair, Clinton F. Stewart, Derek A. Persons and Brian P. Sorrentino
Mol Ther 13: S29-S29; doi:10.1016/j.ymthe.2006.08.085
70. Long Term Correction of beta-Thalassemia by Transplantation of Transduced Hematopoietic Stem Cells
Annarita Miccio, Rossano Cesari, Francesco Lotti, Claudia Rossi, Francesca Tiboni, Francesca Sanvito, Maurilio Ponzoni, Samantha Routledge, Michael Antoniou and Giuliana Ferrari
Mol Ther 13: S30-S30; doi:10.1016/j.ymthe.2006.08.086
71. Alpha 1 Antitrypsin (AAT) Gene Therapy for the Prevention of Type 1 Diabetes
Sihong Song, Yuanqing Lu, Mei Tang, Bin Zhang, Clive Wasserfall, Martha Campbell-Thompson and Mark Atkinson
Mol Ther 13: S30-S30; doi:10.1016/j.ymthe.2006.08.088
72. Intravascular Interaction between Adenovirus and Platelets Promotes Adenovirus Sequestration, Degradation and Toxicity
Daniel Stone, Shaoheng Ni, Zong-Yi Li, Dmitry Shayakhmetov and Andre Lieber
Mol Ther 13: S30-S31; doi:10.1016/j.ymthe.2006.08.089
73. Cats Produce a Potent CTL Response after Neonatal Gene Therapy That Can Be Blocked with CTLA4-Ig
Katherine P. Ponder, Baomei Wang, Ping Wang, Xiucui Ma, Ramin Herati, Bin Wang, Karyn Cullen, Patty O'Donnell, Tina M. Primeau and Mark E. Haskins
Mol Ther 13: S31-S31; doi:10.1016/j.ymthe.2006.08.090
74. Cellular Immunity to Adeno-Associated Virus Capsid Attenuates Transgene Expression in the Liver
Samuel L. Murphy, Denise Sabatino, Federico Mingozzi, Shyrie Edmonson and Katherine High
Mol Ther 13: S31-S32; doi:10.1016/j.ymthe.2006.08.091
75. Protease-Activated Receptor 2 as a Novel Target for Immune Modulation for AAV-Mediated Gene Transfer to Skeletal Muscle
Stefano Baila, Christian Furlan Freguia, Danielle Dunn, Federico Mingozzi, Joerg Schuettrumpf and Valder R. Arruda
Mol Ther 13: S32-S32; doi:10.1016/j.ymthe.2006.08.092
76. In Vivo Suppression of Cytotoxic T Cell Responses by CD4+ Regulatory T Cells Activated by Hepatic Gene Transfer
Lixin Wang, Eric Dobrzynski, Julie Fitzgerald, Ou Cao and Roland W. Herzog
Mol Ther 13: S32-S32; doi:10.1016/j.ymthe.2006.08.093
77. TLR and Myd88 Signaling Pathway Is Required for the Full Induction of Host Adaptive Immune Responses to Adenoviral Vectors and Transgenes
Zhe Zhang, Yan Zhi, Joanita M. Figueredo, Roberto Calcedo, James R. Miller, Guang-Ping Gao and James M. Wilson
Mol Ther 13: S33-S33; doi:10.1016/j.ymthe.2006.08.094
78. Regulation of Immune Responses Against Factor VIII Following Nonviral Gene Transfer in Hemophilia A and FOXP3 Transgenic Mouse Models
Benjamin R. Harmeling, Steven Ziegler, Troy Torgerson, Liping Chen, Hans D. Ochs, David J. Rawlings and Carol H. Miao
Mol Ther 13: S33-S33; doi:10.1016/j.ymthe.2006.08.095
79. Systemic Administration of Lentiviral Vectors Triggers Innate Host Responses
Brian D. Brown, Ehud Hauben, Giovanni Sitia, Anna Zingale, Lucia Sergi Sergi, Lucca Guidotti, Maria Grazia Roncarolo and Luigi Naldini
Mol Ther 13: S33-S34; doi:10.1016/j.ymthe.2006.08.096
80. Pre-Existing Cytotoxic T-Lymphocyte (CTL) Responses to the AAV CAP Protein Do Not Interfere with AAV Transgene Expression in Mice
William M. Siders, Johanne Kaplan, Michael Lukason, Jacqueline Shields, Lisa Woodworth, Sam Wadsworth and Abraham Scaria
Mol Ther 13: S34-S34; doi:10.1016/j.ymthe.2006.08.097
81. Hippocampal Gene Knockdown of BACE1 by Lentiviral Gene Transfer of siRNA Reduces Amyloid Pathology and Improves Memory Performance in APP Transgenic Mice
Oded Singer, Robert A. Marr, Edward Rockenstein, Leslie Crow, Fred H. Gage, Inder M. Verma and Eliezer Masliah
Mol Ther 13: S34-S34; doi:10.1016/j.ymthe.2006.08.099
82. Cftr Gene Targeting in Murine ES Cells Mediated by the SFHR Technique
Federica Sangiuolo, Maria Favia, Lorenzo Guerra, Antonio Filareto, Maria Lucia Scaldaferri, Rosa Caroppo, Paola Spitalieri, Ruggiero Mango, Emanuela Bruscia, Dieter Gruenert, Valeria Casavola, Massimo De Felici and Giuseppe Novelli
Mol Ther 13: S34-S35; doi:10.1016/j.ymthe.2006.08.100
83. Cell-Type Specific Delivery of siRNAs with Aptamer-siRNA Chimeras
Paloma H. Giangrande, James O. McNamara, Eran Andrecheck, Eli Gilboa and Bruce A. Sullenger
Mol Ther 13: S35-S35; doi:10.1016/j.ymthe.2006.08.101
83. RNA Silencing: Role of Interferon System Components in Non-Specific Effects Induced by Chemically Synthesized Small Interfering RNAs, Enzymatically Synthesized Small Interfering RNAs and Short Hairpin RNAs
Christopher S. McAllister and Charles E. Samuel
Mol Ther 13: S35-S35; doi:10.1016/j.ymthe.2006.08.102
85. Von Willebrand Factor (VWF) Gene Targeting by Double-Strand Break Enhanced Homologous Recombination
Nicole L. Prokopishyn, Brian R. Davis, Jonathan B. Rosenberg, Michael DiCola, Jennifer Brosius, R. Michael Blaese and Richard A. Metz
Mol Ther 13: S35-S36; doi:10.1016/j.ymthe.2006.08.103
86. Inhibition of Choroidal Neovascularization In Vivo by Adenovirus Mediated Delivery of Short Hairpin RNAs Targeting Vascular Endothelial Growth Factor as a Potential Therapy for Age Related Macular Degeneration
Siobhan Cashman and Rajendra Kumar-Singh
Mol Ther 13: S36-S36; doi:10.1016/j.ymthe.2006.08.104
87. Efficient Delivery of Small Interfering RNA Targeting Pro-Inflammatory Cytokines in Experimental Arthritis
Maroun Khoury, Virginie Escriou, Pascale Louis-Plence, Dani|[egrave]|le Noel, Daniel Scherman, Christian Jorgensen, and Florence Apparailly
Mol Ther 13: S36-S36; doi:10.1016/j.ymthe.2006.08.105
88. Synthetic siRNAs for Huntington's Disease Therapy
Patrick D. Staber, Chandra Vargeese, Ines H. Martins, Barry Polisky, Alex Mas-Monteys, Scott Q. Harper and Beverly L. Davidson
Mol Ther 13: S36-S37; doi:10.1016/j.ymthe.2006.08.106
89. Gene Targeting of |[beta]|-Globin IVS2 Using Sequence-Specific Peptide Nucleic Acids
Jean Y. Kuan, Ryszard Kole, Peter E. Nielsen and Peter M. Glazer
Mol Ther 13: S37-S37; doi:10.1016/j.ymthe.2006.08.107
90. miRNA Shuttles Improve Therapeutic RNAi
Ryan L. Boudreau and Beverly L. Davidson
Mol Ther 13: S37-S37; doi:10.1016/j.ymthe.2006.08.108
91. Retroviral Vector Integrations Relate to Hematopoietic Stem Cell Gene Expression Patterns
Martijn H. Brugman, Karin Pike-Overzet, Carla Oerlemans-Bergs, Sigrid Swagemakers, Dick de Ridder, Frank J.T. Staal, Monique M.A. Verstegen and Gerard Wagemaker
Mol Ther 13: S37-S38; doi:10.1016/j.ymthe.2006.08.110
92. Gene Transfer to Ocular Stem Cells by Early Gestational Intra-Amniotic Injection of Lentiviral Vector
Masayuki Endo, Phil W. Zoltick, Daniel C. Chung, Jean Bennett and Alan W. Flake
Mol Ther 13: S38-S38; doi:10.1016/j.ymthe.2006.08.111
93. Increased Number of Lung CD34+ Sca-1+ Putative Stem Cells Mediated by Adenovirus Overexpression by Sonic Hedgehog in the Respiratory Tract of Adult Mice
Anja Krause, Ju Joh, Austen Gess, Howard Lou, Ronald G. Crystal and Stefan Worgall
Mol Ther 13: S38-S38; doi:10.1016/j.ymthe.2006.08.112
94. Modulation of Postnatal Muscle-Derived Stem Cell Fate Using siRNA
Jonathan B. Pollett, Karin A. Corsi, Jessica Tebbets, Bridget M. Deasy and Johnny Huard
Mol Ther 13: S39-S39; doi:10.1016/j.ymthe.2006.08.113
95. Effective Genetic Engineering of Human Embryonic Stem Cells Using the Sleeping Beauty Transposon System
Andrew Wilber, Jonathan L. Linehan, Xinghui Tian, R. Scott McIvor and Dan S. Kaufman
Mol Ther 13: S39-S39; doi:10.1016/j.ymthe.2006.08.114
96. Enforced HoxB4 Expressed Hematopoietic Stem Cells Transdifferentiate into Oligodendrocytes in Adult Mouse Brain
Noriko Miyake, Koichi Miyake, Sanae Hisayasu, Stefan Karlsson and Takashi Shimada
Mol Ther 13: S39-S40; doi:10.1016/j.ymthe.2006.08.115
97. Translational Studies toward Optimizing In Vivo Bone Marrow Stem Cell Gene Transfer Using Lentiviral Vector
D. Nicole Worsham, Daren Wang, Christof von Kalle, David A. Williams and Dao Pan
Mol Ther 13: S40-S40; doi:10.1016/j.ymthe.2006.08.116
98. Enrichment and Characterization of Ovarian Cancer Stem Cells
Zong Yi Li, Robert Strauss, Pavel Sova, Shaoheng Ni, Mujun Yu, Dmitry Shayakhmetov, Charles Drescher, Nicole Urban and Andre Lieber
Mol Ther 13: S40-S41; doi:10.1016/j.ymthe.2006.08.117
99. Dedifferentiation of Myotubes and Redifferentiation into an Osteogenic Lineage: A Cre-Lox System Study
Anne Olshanski, Hairong Peng, Xiao Xiao and Johnny Huard
Mol Ther 13: S41-S41; doi:10.1016/j.ymthe.2006.08.118
100. Inducible and Reversible Transgene Expression in Human Stem Cells Stably Transduced by Novel Lentiviral Vectors
Betty Y. Zhou, Zhaohui Ye, Peter Gao and Linzhao Cheng
Mol Ther 13: S41-S41; doi:10.1016/j.ymthe.2006.08.119
101. Molecular Mechanism Responsible for High Level Transgene Expression in Murine and Nonhuman Primate Liver with the Second Generation of Novel AAV Serotype Vectors
You Lu, Xun Sun, Larry T. Bish, Julie C. Johnston, Roberto Calcedo, Rebecca L. Grant, Gaung-Ping Gao and James M. Wilson
Mol Ther 13: S42-S42; doi:10.1016/j.ymthe.2006.08.121
102. Activation of the LMO2 Gene in Human Lymphoid Cells by rAAV-Mediated Targeted Insertion of a Single LTR Expression Cassette into the First Intron
Byoung Y. Ryu, John T. Gray, David M. Bodine and Arthur W. Nienhuis
Mol Ther 13: S42-S42; doi:10.1016/j.ymthe.2006.08.122
103. A Screen for Host Cellular Proteins That Interact with Adeno-Associated Virus Capsid Proteins Reveals Proteins Involved in AAV8 Transduction
Bassel Akache, Sally Fuess, Dirk Grimm and Mark A. Kay
Mol Ther 13: S42-S43; doi:10.1016/j.ymthe.2006.08.123
104. Role of the HI Loop in the Adeno-Associated Virus (AAV) Life Cycle
Nina DiPrimio, Aravind Asokan and Richard J. Samulski
Mol Ther 13: S43-S43; doi:10.1016/j.ymthe.2006.08.124
105. Interactions between Modified AAV Vectors and Alternative Cell Surface Receptors Define Intercellular Trafficking Pathways and Tranduction in Human Vascular Endothelial Cells
Matthew D. Stachler and Jeffrey S. Bartlett
Mol Ther 13: S43-S43; doi:10.1016/j.ymthe.2006.08.125
106. rAAV2 Traffics through Both the Late and Recycling Endosomes in a Dose-Dependent Fashion
Wei Ding, Liang N. Zhang, Charles Yeaman and John F. Engelhardt
Mol Ther 13: S44-S44; doi:10.1016/j.ymthe.2006.08.126
107. |[alpha]|2, 3 and |[alpha]|2,6 N-Linked Sialic Acid Facilitate Efficient Binding and Transduction by Adeno-Associated Virus Type 1 and 6
Zhijian Wu and R. Jude Samulski
Mol Ther 13: S44-S44; doi:10.1016/j.ymthe.2006.08.127
108. Study of an AAV-8 Capsid Mutant with Direct Heparin Binding Capability but Reduced Efficiency in Liver-Targeted Transduction
Xuan Shen, Hui Xu, Theresa Storm and Mark A. Kay
Mol Ther 13: S44-S45; doi:10.1016/j.ymthe.2006.08.128
109. Episomal AAV Vector Genome in the Histone-Associated Chromatin Form Is Capable of Superior Transcription with HDAC Inhibitor
Takashi Okada, Ryosuke Uchibori, Mayumi Iwata-Okada, Mutsuko Nonaka-Sarukawa, Takayuki Ito, Hiroaki Mizukami, Akihiro Kume and Keiya Ozawa
Mol Ther 13: S45-S45; doi:10.1016/j.ymthe.2006.08.129
110. Investigation of Biochemical Factors That May Influence Immunogencity of AAV2 Vectors
Bernd Hauck, Federico Mingozzi, Valder Arruda, Katherine A. High and J. Fraser Wright
Mol Ther 13: S45-S45; doi:10.1016/j.ymthe.2006.08.130
111. Post-Transcriptional Gene Silencing of Alpha-1 Antitrypsin by Small Interfering RNAs (siRNA)
Pedro E. Cruz, Alexandra Golant and Terence R. Flotte
Mol Ther 13: S45-S46; doi:10.1016/j.ymthe.2006.08.131
112. Overexpression of the Coxsackie Adenovirus Receptor (CAR) Gene Influences AAV2 Transduction in Human Trabecular Meshwork Cells
Guorong Li and Teresa Borras
Mol Ther 13: S46-S46; doi:10.1016/j.ymthe.2006.08.132
113. Transduction of Neural Cells in Primate Brain Using Adeno-Associated Virus (AAV) Serotypes 2 and 5
Eleni A. Markakis, Csaba Leranth, Jeremy Bober, R. Jude Samulski, J.E. Rabinowitz, X. Zhou, Kenneth Vives and D. Eugene Redmond Jr
Mol Ther 13: S46-S47; doi:10.1016/j.ymthe.2006.08.133
114. Revisiting rAAV Vector Integration in scid Mice: DNA-PKcs Deficiency Does Not Substantially Increase Integration Frequency in Hepatic and Non-Hepatic Tissues In Vivo
Katsuya Inagaki, Theresa A. Storm, Mark A. Kay and Hiroyuki Nakai
Mol Ther 13: S47-S47; doi:10.1016/j.ymthe.2006.08.134
115. Whole Genome Analysis Shows That AAV Integrates at Chromosome 19 AAV-S1 Sites and Other Chromosomal Sites That Frequently Share GGTC Micro-Homology with the AAV P5 Promoter
Horace R. Drew III, Linda J. Lockett and Gerald W. Both
Mol Ther 13: S47-S47; doi:10.1016/j.ymthe.2006.08.135
116. The Proposed AAV Serotypes 10 and 11 Serologically Cross-React with AAV8 and AAV4
Luk H. Vandenberghe, James R. Miller, Gaung-Ping Gao, Roberto Calcedo and James M. Wilson
Mol Ther 13: S47-S48; doi:10.1016/j.ymthe.2006.08.136
117. HSPG Binding Properties of Adeno-Associated Virus Retargeting Mutants and Consequences for Their In Vivo Tropism
Daniela Goldnau, Luca Perabo, Kathryn White, Jan Endell, Sibille Humme, Lorraine Work, Hanna Jannicki, Michael Hallek, Andrew H. Baker and Hildegard Buening
Mol Ther 13: S48-S48; doi:10.1016/j.ymthe.2006.08.137
118. In Vivo Tracking of Long Term Gene Expression of AAV1 Using Fluorescence Imaging System
Ryuichi Yoneyama, Julieta Palomeque, Kozo Hoshino, Alec M. De Grand, John V. Frangioni and Roger Joseph Hajjar
Mol Ther 13: S48-S49; doi:10.1016/j.ymthe.2006.08.138
119. Intrahepatic Injection of rAAV Serotype 2 Overcomes Gender-Related Differences on Liver Transduction
Kepa Berraondo, Julien S. Crettaz, Laura Ochoa, Astrid Paneda, Jesus Prieto, Inaki F. Troconiz and Gloria Gonz|[aacute]|lez-Aseguinolaza
Mol Ther 13: S49-S49; doi:10.1016/j.ymthe.2006.08.139
120. Tropism and Toxicity of Adeno-Associated Viral Vector Serotypes on Neurons and Glia In Vitro
Doug B. Howard, Kathleen Powers, Barry J. Hoffer, Yun Wang and Brandon K. Harvey
Mol Ther 13: S49-S49; doi:10.1016/j.ymthe.2006.08.140
121. Adenovirus Titers Determined by Quantitative Real-Time PCR Correlate with Infectious Titers
Maria A. Thomas, Peter Krajcsi, Drew L. Lichtenstein, Ann E. Tollefson and William S.M. Wold
Mol Ther 13: S49-S50; doi:10.1016/j.ymthe.2006.08.142
122. Generation of a Family of Ad5 Mutants with Slowed Packaging Kinetics but Non-Affected Packaging Efficiency
Raul Alba, Patrick Hearing, Assumpcio Bosch and Miguel Chillon
Mol Ther 13: S50-S50; doi:10.1016/j.ymthe.2006.08.143
123. Cysteine Protease Inactivation of Adenovirus Is Responsible for Thermal Stress-Induced Adenovirus Infectivity Loss
De-Min Zhu, Donna Williams and Shilu Wu
Mol Ther 13: S50-S50; doi:10.1016/j.ymthe.2006.08.144
124. Optimizing Adenoviral-Based Vaccination by Combining an RGD-Modified Capsid with a Helper-Dependent Adenovirus
Airi Harui, Michael D. Roth and Saroj K. Basak
Mol Ther 13: S50-S51; doi:10.1016/j.ymthe.2006.08.145
125. Enhancement of Virus Mediated Gene Transfer by Polycationic Compounds
Saara Lehmusvaara, Eveliina Pasanen, Outi Rautsi, Tanja Hakkarainen, Marika Ruponen and Jarmo Wahlfors
Mol Ther 13: S51-S51; doi:10.1016/j.ymthe.2006.08.146
126. Evaluation of Replication Competent and Replication Incompetent Adenovirus-Mediated Toxicity in Human Adrenocortical Cells
Urska Matkovic, Monia Pacenti, Marta Trevisan, Giulia Masi, Luisa Barzon and Giorgio Palu
Mol Ther 13: S51-S52; doi:10.1016/j.ymthe.2006.08.147
127. Modulation of Adenoviral Vector Transduction by Hyaluronan and CD44 In Vivo
Joshua N. Mallam, Saumya Chaudhuri, Patricia Chevez-Barrios, Lalita Wadhwa, Mary Y. Hurwitz and Richard L. Hurwitz
Mol Ther 13: S52-S52; doi:10.1016/j.ymthe.2006.08.148
128. Evaluation of a CD46-Transgenic Mouse as a Model for Adenovirus Distribution and Expression
Emma Andersson, Ida Grundberg, Karin Edlund and G|[ouml]|ran Wadell
Mol Ther 13: S52-S52; doi:10.1016/j.ymthe.2006.08.149
129. Adenovirus Serotype 35 Vector-Mediated Transduction in Mouse Hematopoietic Stem Cells Isolated from Human CD46-Transgenic Mice
Fuminori Sakurai, Kenji Kawabata, Takao Hayakawa and Hiroyuki Mizuguchi
Mol Ther 13: S52-S53; doi:10.1016/j.ymthe.2006.08.150
130. Insertion of Transgenes into the E3 or L3 Region To Allow Tumor Selective Expression from Armed Oncolytic Adenoviruses
Michael Robinson, Satya Yendluri, Derek Ko, Lynda Hawkins and Karin Jooss
Mol Ther 13: S53-S53; doi:10.1016/j.ymthe.2006.08.151
131. Design and Construction of an Adenovirus Vector Containing Fiber Fibritin/Canine CD40L Fibers Directed to Canine CD40-Expressing Cells
Masaharu Nakayama, Joel N. Glasgow, Bruce F. Smith, Jing Li, Nikolay Korokhov, Natalya Belousova, Kenzaburo Tani and David T. Curiel
Mol Ther 13: S53-S53; doi:10.1016/j.ymthe.2006.08.152
132. Increased GFP Gene Delivery to Human Prostate Cancer Cells Using Trancomplementing Adenoviral Vectors
Elena E. Mitrofanova, Robert C. Unfer, Martha Carvour, Molly Thrall, Jim Higginbotham, Prem Seth and Charles Link
Mol Ther 13: S53-S54; doi:10.1016/j.ymthe.2006.08.153
133. Adenovirus-Light Chain Inhibition of Growth Hormone Release from Pituitary Adenoma Cells
Thais Federici, Qingshan Teng, Mary Garrity-Moses, Christina Krudy, Jun Yang and Nicholas M. Boulis
Mol Ther 13: S54-S54; doi:10.1016/j.ymthe.2006.08.154
134. A Mechanistic and Kinetic Model for the Inactivation of Liquid-Formulated Adenoviral Vectors by the Delayed Onset of a Rapid Period of Penton Disassociation
David Frey and Cassandra Shu
Mol Ther 13: S54-S54; doi:10.1016/j.ymthe.2006.08.155
135. Replication Competent Ad11 Vectors Possess a High Potential for Human Cells Targeted Cancer Therapy
Ya-Fang Mei and Goran Wadell
Mol Ther 13: S54-S54; doi:10.1016/j.ymthe.2006.08.156
136. The Oncolytic Adenovirus Targeting to TERT and Rb Pathway Induced Specific Cytotoxicity to Tumor Cells
Rong Cai, Wei Zhang, Aiwen Dong, Kai Chen, Songbo Qiu, Xinyuan Liu and Cheng Qian
Mol Ther 13: S55-S55; doi:10.1016/j.ymthe.2006.08.157
137. Streamlined Method for the Simultaneous Construction and Purification of Multiple Recombinant Adenoviral Vectors
Thomas P. Quinn, Marylou G. Gibson, Michael Haugwitz, Michael Phelan and Andrew A. Farmer
Mol Ther 13: S55-S55; doi:10.1016/j.ymthe.2006.08.158
138. Targeted Adenoviral Vectors Expressing Soluble TGF|[beta]|RIIFc for Breast Cancer Metastasis
Zhen-Guo Wang Wang, Amanda Pister, M.B. Zafar, Sung Kim and Prem Seth
Mol Ther 13: S55-S55; doi:10.1016/j.ymthe.2006.08.159
139. Manufacture of a Replication-Selective and Enhanced-Lytic Adenovirus Vector
Moria Artlip, Sawako Ishikawa, Scott Jendrek and Dexter T.K. Poon
Mol Ther 13: S55-S55; doi:10.1016/j.ymthe.2006.08.160
140. Enhanced Cell Killing Effect of E1 Modified Adenoviruses Expressing HSV-TK Suicide Gene
Oh-Joon Kwon, Dong Hyun Ko, Jing Hwa Huang, Il-Kyu Choi, Sung-Mi Jung, Joo-Hang Kim, Byoung Chul Cho and Chae-Ok Yun
Mol Ther 13: S56-S56; doi:10.1016/j.ymthe.2006.08.161
141. Ovarian Cancer-Specific Gene Therapy by Oncolytic Adenovirus
Katsuyuki Hamada
Mol Ther 13: S56-S56; doi:10.1016/j.ymthe.2006.08.162
142. pFex: A Highly Efficient Adenoviral Vector System for Fiber Gene Modification
Shawn E. Lupold, Tarana A. Kudrolli, Wasim H. Chowdhurry and Ronald Rodriguez
Mol Ther 13: S56-S56; doi:10.1016/j.ymthe.2006.08.163
143. Development of Telomerase Specific Antineoplastic Adenovirus Telomelysin (OBP-301): Establishment of Useful Assay and Assessment for Antitumor Activity
Yuuri Hashimoto, Fuminori Teraishi, Yuichi Watanabe, Shunsuke Kagawa, Hitoshi Kawamura, Katsuyuki Nagai, Noriaki Tanaka, Yasuo Urata and Toshiyoshi Fujiwara
Mol Ther 13: S56-S56; doi:10.1016/j.ymthe.2006.08.164
144. Magnetically Responsive Nanoparticles Enhance Adenoviral Gene Delivery in Cultured Smooth Muscle Cells
Michael Chorny, Ilia Fishbein, Ivan Alferiev, Origene Nyanguile and Robert J. Levy
Mol Ther 13: S57-S57; doi:10.1016/j.ymthe.2006.08.165
145. Detection of the Primary Destabilizing Modification of Liquid-Formulated Adenoviral Vectors by Anion-Exchange High Performance Liquid Chromatography
Cassandra Shu and David Frey
Mol Ther 13: S57-S57; doi:10.1016/j.ymthe.2006.08.166
146. Development of Modified Adenovirus Vectors with Reduced Innate Immune Response
Hiroyuki Mizuguchi, Naoya Koizumi, Kenji Kawabata, Fuminori Sakurai and Takao Hayakawa
Mol Ther 13: S57-S58; doi:10.1016/j.ymthe.2006.08.167
147. Effective Gene Transfer to Human Glioma Cells Using High Capacity Adenoviral Vectors: Human Glioma Cells Express Substantial Levels of CAR and Integrin Adenoviral Co-Receptors
Marianela Candolfi, James F. Curtin, Weidong Xiong, Kurt M. Kroeger, Chunyan Liu, Altan Rentsendorj, Hasmik Agadjanian, Lali Medina-Kauwe, Philip Ng, Donna Palmer, Pedro R. Lowenstein and Maria G. Castro
Mol Ther 13: S58-S58; doi:10.1016/j.ymthe.2006.08.168
148. Characterisation of a Chimpanzee Adenovirus That Is Highly Infectious to Human Low-Passage Glioma Cells
Johan Skog, Emma Andersson, Karin Edlund, Ya-Fang Mei and G|[ouml]|ran Wadell
Mol Ther 13: S58-S58; doi:10.1016/j.ymthe.2006.08.169
149. Coxsackie and Adenovirus Receptor Binding Ablation Reduces Adenovirus Liver Tropism and Toxicity
Minjung Kim, A-Rum Yoon, Ji Young Yoo, Min-Ju Kim, Yoon-A Kang, Joo-Hang Kim and Chae-Ok Yun
Mol Ther 13: S58-S59; doi:10.1016/j.ymthe.2006.08.170
150. Metabolically Biotinylated Helper Dependent Adenovirus: A New and Rapid Approach for Targeting of High-Capacity Adenoviral Vector
Vincenzo Cerullo, Michael P. Seiler, Christopher Clarke, Aylet Erez, Michael A. Barry and Brendan Lee
Mol Ther 13: S59-S59; doi:10.1016/j.ymthe.2006.08.171
151. Treatment of Experimental Schwannomas with HSV Recombinant and Amplicon Vectors
Shilpa Prabhakar, Shanta Messerli, Samuel Rabkin, Robert Martuza and Xandra O. Breakefield
Mol Ther 13: S59-S59; doi:10.1016/j.ymthe.2006.08.174
152. Comparable Protection of Human T-Cells from High Dose Challenges of HIV-1 Using Gutless and Non-Gutless rSV40 Vectors Carrying Anti-Integrase scFv: Implications for Gene Therapy
Elena I. Marusich and David S. Strayer
Mol Ther 13: S59-S60; doi:10.1016/j.ymthe.2006.08.175
153. A Novel Gene Expression System Using Human Artificial Chromosome-HSV-1 Vectors
Daniela Moralli, Kirsty Simpson, Richard Wade-Martins and Zoia Larin Monaco
Mol Ther 13: S60-S60; doi:10.1016/j.ymthe.2006.08.176
154. Tetracycline-Inducible HSV Amplicon Vectors with Expanded Range of Gene Expression Regulation
Laryssa A. Comer, Juliet L. Fernandez, Sara M. Camp, Jessica C. Tebbets, Xandra O. Breakefield and Miguel Sena-Esteves
Mol Ther 13: S60-S60; doi:10.1016/j.ymthe.2006.08.177
155. Soluble HVEM Mediates Herpes Simplex Virus 1 (HSV-1) Infection of gD Receptor-Negative Cells
Hyunjung Baek, June-young Kyoung, Juhee Park, Kee-ho Lee, William F. Goins, Justus B. Cohen, Joseph C. Glorioso and Heechung Kwon
Mol Ther 13: S61-S61; doi:10.1016/j.ymthe.2006.08.178
156. Rapid Methods of Engineering HSV Amplicon Vectors
Kazue Kasai and Yoshinaga Saeki
Mol Ther 13: S61-S61; doi:10.1016/j.ymthe.2006.08.179
157. A Mutant Type 2 Herpes Simplex Virus Deleted for the Protein Kinase Domain of the ICP10 Gene Is a Potent Oncolytic Virus
Xinping Fu, Lihua Tao and Xiaoliu Zhang
Mol Ther 13: S61-S62; doi:10.1016/j.ymthe.2006.08.180
158. Real-Time Visualization of Neuronal Differentiation and Neurite Projection Using an Indicator HSV Amplicon Vector
Shigeru Tanaka, Kazue Kasai, E. Antonio Chiocca and Yoshinaga Saeki
Mol Ther 13: S61-S62; doi:10.1016/j.ymthe.2006.08.181
159. Novel Oncolytic HSV Armed with Platelet Factor 4, an Antiangiogenic Agent, Shows Enhanced Efficacy
Ta-Chiang Liu, Tingguo Zhang, Hiroshi Fukuhara, Toshi Kuroda, Tomoki Todo, Robert L. Martuza, Samuel D. Rabkin and Andreas Kurtz
Mol Ther 13: S62-S62; doi:10.1016/j.ymthe.2006.08.182
160. Innate Immune Responses to Viral Vectors Are Modulated by Complement Inhibitors in an Ex Vivo Model Using Whole Human Blood
Lindsay J. Stanbridge, Graciela Elgue, Javier Sanchez, Vincent Dussupt, Lucy C. Hudson, John D. Lambris, Thomas Totterman, Norman J. Maitland and Bo Nilsson
Mol Ther 13: S62-S63; doi:10.1016/j.ymthe.2006.08.183
161. Truncated Vesicular Stomatitis Virus G-Protein Improves Baculovirus Transduction Efficiency In Vitro and In Vitro
Minna U. Kaikkonen, Jani K. Raty, Kari J. Airenne, Thomas Wirth, Tommi Heikura and Seppo Yla-Herttuala
Mol Ther 13: S63-S63; doi:10.1016/j.ymthe.2006.08.184
162. Bioluminescence Imaging of a Tetanus Toxin C-Terminal Fusion Protein after Vector Delivery
Lisa Pike and Sam Wang
Mol Ther 13: S63-S63; doi:10.1016/j.ymthe.2006.08.185
163. Baculovirus-Mediated Gene Transfer in New Zealand White Rabbit Skeletal Muscle
Tommi T. Heikura, Miia M. Roschier, Anssi J. Mahonen, Hanna P. Lesch, Tuomas T. Rissanen, Olli H. Laitinen, Kari J. Airenne and Seppo Yla-Herttuala
Mol Ther 13: S63-S63; doi:10.1016/j.ymthe.2006.08.186
164. HSV-1 Vector-Based Assay To Identify Inhibitors of the Vanilloid Receptor
Rahul Srinivasan, Darren Wolfe, Shaohua Huang, David Krisky, Adrian Sculptoreanu, Peter A. Friedman, William C. de Groat and Joseph C. Glorioso
Mol Ther 13: S63-S64; doi:10.1016/j.ymthe.2006.08.187
165. Enhanced Baculovirus-Mediated Transduction of Human Cancer Cells by Tumor-Homing Peptides
Anna R. Makela, Heli Matilainen, Daniel White and Christian Oker-Blom
Mol Ther 13: S64-S64; doi:10.1016/j.ymthe.2006.08.188
166. OncoVEX: A Family of Oncolytic Herpes Simplex Viruses Optimised for Therapeutic Use
Robert S. Coffin, Binlei Liu, Han Ziqun, Magdalena Assenberg, Suzanne Thomas, Jennifer Hu and Guy Simpson
Mol Ther 13: S64-S64; doi:10.1016/j.ymthe.2006.08.189
167. Polyethyleneimines as Vehicles for Oral Gene Delivery
Eytan A. Klausner and Kam W. Leong
Mol Ther 13: S64-S65; doi:10.1016/j.ymthe.2006.08.191
168. Peptide Aldehyde Inhibitors of the Proteasome as Improved Gene Transfer Agents
Molly E. Martin, Ji-Seon Kim and Kevin G. Rice
Mol Ther 13: S65-S65; doi:10.1016/j.ymthe.2006.08.192
169. Patterned Substrate-Mediated DNA Delivery Using Soft Lithography for Neural Tissue Engineering
Tiffany L. Houchin and Lonnie D. Shea
Mol Ther 13: S65-S66; doi:10.1016/j.ymthe.2006.08.193
170. Transfected Cell Arrays for Assessment of Estrogen Receptor Activation in Breast Cancer Cells
Angela K. Pannier, Zain Bengali, Eric A. Ariazi, V. Craig Jordan and Lonnie D. Shea
Mol Ther 13: S66-S66; doi:10.1016/j.ymthe.2006.08.194
171. PEG-b-PPA/DNA Micelles for Liver Targeted-Gene Delivery
Xuan Jiang, Hui Dai, Kam W. Leong and Hai-Quan Mao
Mol Ther 13: S66-S66; doi:10.1016/j.ymthe.2006.08.195
172. Spatially-Controlled Delivery of Cyclodextrin-Based Polyplexes from Solid Surfaces
In-Kyu Park, Horst A. von Recum, Shaoyi Jiang and Suzie H. Pun
Mol Ther 13: S67-S67; doi:10.1016/j.ymthe.2006.08.196
173. Novel Cell-Specific Gene Delivery for Tumors Using a Drug or Gene Delivery System Based on Responses to Intracellular Signals (D-RECS) Concept
Yoshiki Katayama, Jeong Hun Kang, Daisuke Asai, Takeshi Mori and Takuro Niidome
Mol Ther 13: S67-S67; doi:10.1016/j.ymthe.2006.08.197
174. Chloroquine and Chloroquine Analogues in Non-Viral Delivery
Jianjun Cheng, Ryan Zeidan, Swaroop Mishra, Aijie Liu, Suzie Pun, Greg Jensen, Nathalie Bellocq, Rajan Kulkarni and Mark E. Davis
Mol Ther 13: S67-S68; doi:10.1016/j.ymthe.2006.08.198
175. Delivery Via Non-Viral Options to the Auditory Structures
Mark J. Praetorius, Christoph Klingmann, Douglas E. Brough, Peter K. Plinkert and Hinrich Staecker
Mol Ther 13: S68-S68; doi:10.1016/j.ymthe.2006.08.199
176. An Inhibitor of Fumarylacetoacetate Hydrolase (Fah) for Selection of Transplanted Hepatocytes and Gene Correction In Vivo
Karsten Wursthorn, John F. Witte, R.L. Bateman, Milton Finegold, Ronald W. McClard and Markus Grompe
Mol Ther 13: S68-S68; doi:10.1016/j.ymthe.2006.08.200
177. A Novel Class of Cationic Amphiphiles for Airway Gene Delivery
Keun-Sik Kim, Qun Li, Takeshi Suda and Dexi Liu
Mol Ther 13: S68-S69; doi:10.1016/j.ymthe.2006.08.201
178. Structure-Activity Relationships in a Library of Pyridinium Non-Viral Vectors for Gene Delivery
Marc A. Ilies, Betty H. Johnson, Aaron Miller, William A. Seitz, E. Brad Thompson and Alexandru T. Balaban
Mol Ther 13: S69-S69; doi:10.1016/j.ymthe.2006.08.202
179. In Vivo Delivery of DNA or siRNA Formulated into Nanoparticles with Linear PEI
Anne-Laure Bolcato-Bellemin, Marie-Elise Bonnet and Patrick Erbacher
Mol Ther 13: S69-S69; doi:10.1016/j.ymthe.2006.08.203
180. Transfection Efficiency of Albumin-Containing DNA/Polyethylenimine Complexes in Primary Human Respiratory Epithelial Cells and In Vivo in the Murine Airways
Sante Di Gioia, Joanna Rejman, Salvatore Carrabino, Elena Copreni, Lucia Palmieri and Massimo Conese
Mol Ther 13: S70-S70; doi:10.1016/j.ymthe.2006.08.204
181. Quantitative Evaluation of Long Term Gene Expression In Vivo after Delivery of Polyethylenimine-Conjugated Sleeping Beauty Transposon DNA
Kelly M. Podetz-Pedersen, Jason B. Bell, Terry W. Steele, Joel L. Frandsen, Thomas W. Shier, R. Scott McIvor and Perry B. Hackett
Mol Ther 13: S70-S70; doi:10.1016/j.ymthe.2006.08.205
182. Branched Chitosan Oligomers Enhance Gene Delivery In Vitro and after Lung Administration In Vivo
Mohamed M. Issa, Magnus K|[ouml]|ping-H|[ouml]|gg|[aring]|rd, Kristoffer Tommeraas, Kjell M. V|[aring]|rum, Bj|[oslash]|rn E. Christensen, Olav Smids|[oslash]|rd and Per Artursson
Mol Ther 13: S70-S71; doi:10.1016/j.ymthe.2006.08.206
183. Targeting of Muscle Cells with Functionalised Lipid Particles
Harald Heider, Sandro Rusconi and Denis Bron
Mol Ther 13: S71-S71; doi:10.1016/j.ymthe.2006.08.207
184. Novel Cationic Multivalent Lipids Show Improved Delivery of siRNA and DNA
Nathan F. Bouxsein, Kai K. Ewert, Christopher S. McAllister, Heather M. Evans, Charles E. Samuel and Cyrus R. Safinya
Mol Ther 13: S71-S71; doi:10.1016/j.ymthe.2006.08.208
185. Structural Advantage of Dendritic poly(L- lysine) in Gene Delivery In Vitro and In Vivo
Takuro Niidome, Masato Yamagata, Takayuki Iida, Takahito Kawano, Kouhei Shiba and Yoshiki Katayama
Mol Ther 13: S72-S72; doi:10.1016/j.ymthe.2006.08.209
186. Efficient In Vivo Gene Expression by DNA/ Polycation/Polyanion Ternary Complexses
Tomoko Ito, Keiko Abe, Chieko Yoshihara, Naoko Iida Tanaka and Yoshiyuki Koyama
Mol Ther 13: S72-S73; doi:10.1016/j.ymthe.2006.08.210
187. Modular Cationic Peptides as Gene Delivery Agents
Rukkumani Rajagopalan, Jennifer Xavier, Nalam M. Rao and Vijaya Gopal
Mol Ther 13: S73-S73; doi:10.1016/j.ymthe.2006.08.211
188. Internalization of Novel Delivery Vector TAT-Streptavidin into Human Cells
Johanna Rinne, Brian Albarran, Juulia Jylh|[auml]|v|[auml]|, Teemu O. Ihalainen, Pasi Kankaanp|[auml]||[auml]|, Vesa P. Hyt|[ouml]|nen, Patrick S. Stayton, Markku S. Kulomaa and Maija Vihinen-Ranta
Mol Ther 13: S73-S73; doi:10.1016/j.ymthe.2006.08.212
189. Enhanced Nuclear Import and Transfection Efficiency by Disaccharide-Modified PEIs
Takeshi Nagasaki, Toshiki Shiga, Tomomi Jinta and Seiji Shinkai
Mol Ther 13: S73-S74; doi:10.1016/j.ymthe.2006.08.213
190. Gene Delivery without Nonspecific Biological Response: Comprehensive Analysis of Cell Bioactivity Using a Novel Cationic Polymer-Based System
Kayo Masago, Keiji Itaka, Nobuhiro Nishiyama, Shigeto Fukushima and Kazunori Kataoka
Mol Ther 13: S74-S74; doi:10.1016/j.ymthe.2006.08.214
191. Design, Synthesis, and Characterization of a New Class of Quaternary Ammonium Gemini Amphiphiles for Gene Delivery
Qun Li, Guisheng Zhang, Wei Xu and Dexi Liu
Mol Ther 13: S74-S74; doi:10.1016/j.ymthe.2006.08.215
192. RGD- Functionalised Liposome for Tumour Targeting
Jianmeizi (May) Chen, Ayesha Ahmad, Andrew D. Miller, Michael Keller, Eric Perouzel and Michael R. Jorgensen
Mol Ther 13: S74-S75; doi:10.1016/j.ymthe.2006.08.216
193. Gene Transfection Using Inorganic Particle/PVA/DNA Complexes Prepared by Ultra High Pressure Technology
Tsuyoshi Kimura, Kwangoo Nam, Sihngo Mutsuo, Hidekazu Yoshizawa, Masahiro Okada, Tsutomu Furuzono, Toshiya Fujisato and Akio Kishida
Mol Ther 13: S75-S75; doi:10.1016/j.ymthe.2006.08.217
194. Development of Novel DNA Formulations Based on Polymers and Cyclodextrin for Gene Delivery to the Muscle
Caroline Roques, Andr|[eacute]| Salmon, Marc Y. Fiszman, Elias Fattal and Yves Fromes
Mol Ther 13: S75-S76; doi:10.1016/j.ymthe.2006.08.218
195. Tat Peptide Conjugates of Low Molecular Weight Polyethylenimine as Effective Non-Viral Gene Delivery Vectors
Shu Wang
Mol Ther 13: S76-S76; doi:10.1016/j.ymthe.2006.08.219
196. Genetic Manipulation of Dendritic Cells through the Use of Immunolipoplexes To Induce T Cell-Specific Tolerance In Vivo
Peng H. Tan, Robert I. Lechler, Giovanna Lombardi and Andrew J.T. George
Mol Ther 13: S76-S76; doi:10.1016/j.ymthe.2006.08.220
197. Development of Chitosan Nanoparticles for Gene Delivery System
Zhi-Hong Yang, Toshinori Sato and Yoshiyuki Koyama
Mol Ther 13: S76-S77; doi:10.1016/j.ymthe.2006.08.221
198. In Vitro and In Vivo Gene-Transferring Characteristics of Novel Cationic Lipids, DMKD(O,O|[prime]|-dimyristyl-N-lysyl aspartate) and DMKE(O,O|[prime]|-dimyristyl-N-lysyl Glutamate)
Hong Sung Kim, In Ho Song, Jong Chul Kim, Eun Jung Kim, Yeon Kyung Lee, Jung Seok Kim, Kyung Hye Koo, Doo Ok Jang and Yong Serk Park
Mol Ther 13: S77-S77; doi:10.1016/j.ymthe.2006.08.222
199. Plasmid DNA Delivery by Nanoparticule Loaded Coronary Stent
Cunxian Song, Xu Jin, Dunwan Zhu, Chao Zhang, Hongfan Sun, Linhua Zhang and Kangde Yao
Mol Ther 13: S77-S78; doi:10.1016/j.ymthe.2006.08.223
200. A Novel Non-Viral Polymer for Plasmid Delivery to Bone Marrow Stromal Cells (BMSC)
Basak A. Clements, Vanessa Incani, Cezary Kucharski, Afsaneh Lavasanifar and Hasan Uludag
Mol Ther 13: S78-S78; doi:10.1016/j.ymthe.2006.08.224
201. Selective Targeting of Nucleic Acid Nanoparticles to Hepatocytes In Vivo
Darren H. Wakefield, So Wong, David B. Rozema, Jason J. Klein and Jon A. Wolff
Mol Ther 13: S78-S78; doi:10.1016/j.ymthe.2006.08.225
202. Effect of Modification with Lipophilic Fragments and Inclusion of Endosomolytic Peptide on Transfection Efficiency Mediated by Lysine Dendrimers
Anna A. Egorova, Polina L. Il'ina, Anton V. Kiselev, Aleksandre N. Baranov, Irina I. Tarasenko, Gennadii P. Vlasov and Vladislav S. Baranov
Mol Ther 13: S78-S78; doi:10.1016/j.ymthe.2006.08.226
203. Salt Conditions during Polyplex Formation Significantly Alters Transfection
Qixin Leng, Jason Kahn, Jingsong Zhu, Puthapparampil Scaria and Archibald J. Mixson
Mol Ther 13: S79-S79; doi:10.1016/j.ymthe.2006.08.227
204. Novel Gene Transduction Technology by Credia TF
Motoyoshi Tanaka, Madoka Tonosaki, Masafumi Umekage, Tomio Konaka, Ikeda Hisafumi and Hirotsugu Uemura
Mol Ther 13: S79-S79; doi:10.1016/j.ymthe.2006.08.228
205. AAV-Mediated Gene Transfer to Muscle and Liver of MPS VI Animal Models
Alessandra Tessitore, Armida Faella, Fabiana Parisi, Mark Haskins and Alberto Auricchio
Mol Ther 13: S79-S79; doi:10.1016/j.ymthe.2006.08.230
206. Frequency and Analysis of Liver Tumors in AAV-Treated B6C3F1 Hybrid Mice
Peter L. Bell, A. David Moscioni, Robert J. McCarter, Di Wu, Guang-Ping Gao, Albert Hoang, Julio San Miguel, Xun Sun, Nelson Wivel, Steven E. Raper, Emma E. Furth, Mark L. Batshaw and James M. Wilson
Mol Ther 13: S80-S80; doi:10.1016/j.ymthe.2006.08.231
207. Long-Term Therapy for PKU in Mice by rAAV Pseudotype 8 Gene Transfer to Liver
Alexandre Rebuffat, Zhaobing Ding, Panco Georgiev and Beat Thony
Mol Ther 13: S80-S80; doi:10.1016/j.ymthe.2006.08.232
208. Sleeping Beauty Transposon-Mediated Long-Term |[alpha]|-L-iduronidase Expression and Correction of Lysosomal Pathology in the Murine Model of Mucopolysaccharidosis (MPS) Type I
Elena L. Aronovich, Jason B. Bell, Lalitha R. Belur, Roland Gunther, Brenda Koniar, David C.C. Erickson, Patricia A. Schachern, R. Scott McIvor, Chester B. Whitley and Perry B. Hackett
Mol Ther 13: S80-S81; doi:10.1016/j.ymthe.2006.08.233
209. Correction of Hunter Syndrome in the MPSII Mouse Model by AAV2/8-Mediated Gene Delivery
Monica Cardone, Vinicia Assunta Polito, Stefano Pepe, Linda Mann, Alessandra D'Azzo, Alberto Auricchio, Andrea Ballabio and Maria Pia Cosma
Mol Ther 13: S81-S81; doi:10.1016/j.ymthe.2006.08.234
210. Permanent Correction of Leptin Deficiency through Cutaneous Gene Therapy. Lentivirus but Not Retrovirus-Transduced Human Keratinocyte Orthotopic Grafts Achieve Therapeutic Systemic Leptin Levels
Laura Rico, Isabel Mirones, Blanca Duarte, Almudena Holguin, Antonio Bernad, Marcela Del Rio and Fernando Larcher
Mol Ther 13: S81-S81; doi:10.1016/j.ymthe.2006.08.235
211. Development of Helper-Dependent Adenovirus (HDAd) Vectors for Gene Therapy in the Mouse Model for Glycogen Storage Disease Type Ia (GSD-Ia)
Dwight D. Koeberl, Lopamudra Banerjee, Baodong Sun, Andrew Bird, Y.T. Chen, Kazuhiro Hiro and Lawrence Chan
Mol Ther 13: S81-S82; doi:10.1016/j.ymthe.2006.08.236
212. Delivery of Galactocerebrosidase Activity to the Peripheral Nervous System of Mice with Globoid Cell Leukodystrophy (Krabbe Disease) by Intramuscular Injection
Mohammad A. Rafi, Han Zhi Rao, Paola Luzi, Mark T. Curtis and David A. Wenger
Mol Ther 13: S82-S82; doi:10.1016/j.ymthe.2006.08.237
213. Improving the Therapeutic Index of Helper-Dependent Adenoviral Vector for Crigler-Najjar Gene Therapy
David Dimmock, Nicola Brunetti-Pierri, Viraj Mane, Donna Palmer, Arthur Beaudet and Philip Ng
Mol Ther 13: S82-S82; doi:10.1016/j.ymthe.2006.08.238
214. Dominant-Negative Interference in the Pahenu2 Mouse: Modified Forms of PAH
Andreas Zori, Dawn D. Yang, Jon-Michael Knapp, Catherine E. Charron, Jennifer E. Embury, Stacy L. Porvasnik and Philip J. Laipis
Mol Ther 13: S82-S83; doi:10.1016/j.ymthe.2006.08.239
215. Treating Hypoparathyroidism through Regulated Expression of Parathyroid Hormone in Skeletal Muscle
Maja Z. Salva and Stephen D. Hauschka
Mol Ther 13: S83-S83; doi:10.1016/j.ymthe.2006.08.240
216. Long Term Portal Vein Administration of AAV-WPRE Vector Results in Increased Incidence of Neoplastic Disease and Hepatic Pathology
Jennifer E. Embury, Catherine C. Charron, Amy E. Poirier, Andreas Zori, Russ Carmichael, Terry R. Flotte and Philip J. Laipis
Mol Ther 13: S83-S83; doi:10.1016/j.ymthe.2006.08.241
217. Comparison of Hepatic Vein and Peripheral Vein Delivery of an AAV2/8 Vector Encoding Human a-Galactosidase A to Rhesus Macaques
Bradley L. Hodges, Qiuming Chu, Jennifer B. Nietupski, Karen M. Ashe, Kristin M. Taylor, Robin J. Ziegler, Seng H. Cheng, John Marshall and Ronald K. Scheule
Mol Ther 13: S84-S84; doi:10.1016/j.ymthe.2006.08.242
218. Gene Therapy and Enzyme Replacement in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis
Michael Chang, David Sleat, Seng Cheng, Marco Passini, Peter Lobel and Beverly L. Davidson
Mol Ther 13: S84-S84; doi:10.1016/j.ymthe.2006.08.243
219. Persistent Correction of Hyperphenylalaninemia Following Liver-Directed, rAAV2/8-Mediated Gene Therapy for Murine Phenylketonuria (PKU)
Cary O. Harding, Melanie B. Gillingham, Elizabeth Daghighi, Andrew Bird and Dwight D. Koeberl
Mol Ther 13: S84-S84; doi:10.1016/j.ymthe.2006.08.244
220. AAV Mediated Gene Transfer of Smad7 in Different Models of Cystic Kidney Diseases
Andrea Keppler, Barbara Leuchs, Carolin Stump, Steven Dooley, Juergen Kleinschmidt and Norbert Gretz
Mol Ther 13: S85-S85; doi:10.1016/j.ymthe.2006.08.245
221. A New Retroviral Gene Therapy Approach for Cystinuria Research
Sreedhar Sagi, Marcus Picard-Maureau, Rudiger Dorries, Peter Alken, Maurice S. Michel and Thomas Knoll
Mol Ther 13: S85-S85; doi:10.1016/j.ymthe.2006.08.246
222. Aberrant Striatal Gene Expression in the Striatum of HPRT-Knockout Mouse
Shaochun Song, C. Ramana Bhasker, Ling Guo and Theodore Friedmann
Mol Ther 13: S85-S85; doi:10.1016/j.ymthe.2006.08.247
223. Proteomic Analysis of the Striatum of Wild Type and HPRT-Deficient Mouse
Ling T. Guo, Charles C. King, Shaochun Song and Theodore Friedmann
Mol Ther 13: S85-S86; doi:10.1016/j.ymthe.2006.08.248
224. Pyruvate Dehydrogenase Complex Deficiency Caused by the Ubiquitin-Proteasome System-Mediated Degradation in E1|[beta]| Subunit
Zongchao Han, Arun Srivastava and Peter Stacpoole
Mol Ther 13: S86-S86; doi:10.1016/j.ymthe.2006.08.249
225. A Novel Mechanism between Diabetes Mellitus Complications and Procalcitonin Gene Expression
Mehmet A. Soylemez, Ceyhan Sayar, Bilge Turkover, Guven Toksoy and Tulay Yardimci
Mol Ther 13: S86-S86; doi:10.1016/j.ymthe.2006.08.250
226. Effective Gene Therapy in an Authentic Mouse Model of Tay-Sachs Related Diseases
Begona Cachon-Gonzlez, Susan Wang, Robin Ziegler, Seng H. Cheng and Timothy M. Cox
Mol Ther 13: S86-S87; doi:10.1016/j.ymthe.2006.08.251
227. Sustained Correction of Hyperphenylalaninemia in Female Pahenu2 Mouse by a Self-Complementary Adeno-Associated Virus Vector
Akihiro Kume, Tsuyoshi Ogura, Takashi Matsushita, Hiroaki Mizukami, Masashi Urabe, Takashi Okada and Keiya Ozawa
Mol Ther 13: S87-S87; doi:10.1016/j.ymthe.2006.08.252
228. AAV Mediated Hypoxia-Inducible VEGF Expression and Neovascular Formation in Ischemic Pig Myocardium
Hua Su, Yerem Yeghiazarians, Andrew Lee, Yu Huang, Janice Arakawa-Hoyt, Jianqin Ye, Gina Orcino, William Growssman and Yuet W. Kan
Mol Ther 13: S87-S87; doi:10.1016/j.ymthe.2006.08.254
229. Use of rAAV Transduced Endothelial Progenitor Cells for the Treatment of Myocardial Infarction in Rat Model
Sabyasachi Sen, Juan Merchan, Jarrod Dean, Marcia Silver, Mary Gavin, Elizabeth Eaton, Tengiz Tkebuchava, Maasaki Ii, Young-Sup Yoon, Douglas W. Losordo and Ryuichi Aikawa
Mol Ther 13: S88-S88; doi:10.1016/j.ymthe.2006.08.255
230. In Vivo Fluorescence Tracking System for Cardiac Stem Cell Therapy
Kozo Hoshino, Hung Q. Ly, Irina Pomerantseva, Yoshiaki Takewa, Ryuichi Yoneyama, Yoshiaki Kawase, Alec M. DeGrande, John V. Frangioni and Roger J. Hajjar
Mol Ther 13: S88-S88; doi:10.1016/j.ymthe.2006.08.256
231. Gene Transfer of a Synthetic Pacemaker Channel into the Heart: A Novel Strategy for Biological Pacing
Yuji Kashiwakura, Hee Choel Cho, Ezana Azene and Eduardo Marb|[aacute]|n
Mol Ther 13: S89-S89; doi:10.1016/j.ymthe.2006.08.257
232. Short-Term, In Vivo Correction of VLCAD Deficiency in Mice: Steps toward a Gene Therapy for Cardiomyopathy
Tien Nguyen, Jan Daniels, Lawrence Merritt, Dietrich Matern, Jerry Vockley, Philip A. Wood and David B. Schowalter
Mol Ther 13: S89-S89; doi:10.1016/j.ymthe.2006.08.258
233. Conjugating Polymer Vector to Magnetic Nanobeads Enhances Local Gene Expression in the Heart
Wenzhong Li, Nan Ma, Leelee Ong, Alexander Kaminski, Peter Lorenz, Brigitte M. Putzer, Ren-Ke Li, Christof Stamm and Gustav Steinhoff
Mol Ther 13: S89-S89; doi:10.1016/j.ymthe.2006.08.259
234. Long Term Effects of pcDNA3-VEGF165 Intramyocardial Transfer after Experimental Myocardial Infarction in the Rat Scar Tissue Extracellular Matrix
Fabio D. Mataveli, Sang W. Han, Aline Mendes, Rose Kanashiro, Paulo Tucci, Helena B. Nader and Maria Aparecida S. Pinhal
Mol Ther 13: S90-S90; doi:10.1016/j.ymthe.2006.08.260
235. Herpes Simplex Virus Vector Mediated Heme Oxygenase Gene Therapy of Heart Ischemia-Reperfusion
William F. Goins, Arthur R. Frampton, Atsunori Nakao, Koji Tomiyama, David S. Clawson, James Wechuck, Shao-hua Huang, David M. Krisky, Justus B. Cohen, Noriko Murase and Joseph C. Glorioso
Mol Ther 13: S90-S90; doi:10.1016/j.ymthe.2006.08.261
236. Ultrasound-Targeted Microbubble Destruction Augments Cardiac AAV-Mediated Gene Transfer after Systemic Administration in Adult Rats
Oliver J. M|[uuml]|ller, Stefanie Schinkel, Hugo A. Katus, J|[uuml]|rgen A. Kleinschmidt and Raffi Bekeredjian
Mol Ther 13: S91-S91; doi:10.1016/j.ymthe.2006.08.262
237. Gene Expression Profiles in Diabetic Cardiomyopathy Following SERCA2a Gene Transfer
Djamel Lebeche, Susumu Sakata, Yuri Sakata, Naoya Sakata, Elie R. Chemaly, Miyako Takaki and Roger J. Hajjar
Mol Ther 13: S91-S91; doi:10.1016/j.ymthe.2006.08.263
238. Knock down Phospholamban To Improve Heart Function by AAV-Mediated shRNA
Xiaochun Lu, Guang Yang, Xiaoying Li and Xiaobing Wu
Mol Ther 13: S91-S92; doi:10.1016/j.ymthe.2006.08.264
239. Histological Measurement of Myocardial Infarct Area Does Not Provide a Sensitive Assessment of Infarct Size in a Mouse Chronic Infarct Model
Junya Takagawa, Yan Zhang, Richard E. Sievers, Neel K. Kapasi, Maelene L. Wong, Yerem Yeghiazarians, Randall J. Lee, William Grossman and Matthew L. Springer
Mol Ther 13: S92-S92; doi:10.1016/j.ymthe.2006.08.265
240. Hemiparkisonism Induced through Unilateral Expression of Adenovirus-Mediated Clostridial Light Chain Gene in the Substantia Nigra
Jun Yang, Qingshan Teng, Mary E. Garrity-Moses, Thais Federici, John Butler, Shearwood McClelland III and Nicholas M. Boulis
Mol Ther 13: S92-S92; doi:10.1016/j.ymthe.2006.08.267
241. A Dose-Ranging Study of AAV-hAADC Therapy in Parkinsonian Monkeys
John R. Forsayeth, Jamie L. Eberling, Laura M. Sanftner, Zhu Zhen, Philip Pivirotto, John Bringas, Janet Cunningham and Krystof S. Bankiewicz
Mol Ther 13: S93-S93; doi:10.1016/j.ymthe.2006.08.268
242. Neuronal Specificity of |[alpha]|-Synuclein Toxicity and the Effect of Parkin Co-Expression in Primates
Toru Yasuda, Masahiko Takada, Hideki Mochizuki and Yoshikuni Mizuno
Mol Ther 13: S93-S93; doi:10.1016/j.ymthe.2006.08.269
243. Control of Undesirable Effects of GDNF Delivered in the Striatum of Healthy Rats Using a Tetracycline-Inducible AAV1 Vector
Abdelwahed Chtarto, Xin Yang, Mansoor Sharifi, Olivier Bockstael, Enni Lehtonen, David Blum, Laurence Abeloos, Jean-Marie Jaspar, Thierry Velu, Jacques Brotchi, Marc Levivier and Liliane Tenenbaum
Mol Ther 13: S93-S93; doi:10.1016/j.ymthe.2006.08.270
244. New Gene Therapy for Parkinson's Disease by Down Regulation of |[alpha]|-Synuclein
Hideki Mochizuki, Hiromi Hayashita-Kinoh, Masanori Yamada and Yoshikuni Mizuno
Mol Ther 13: S93-S94; doi:10.1016/j.ymthe.2006.08.271
245. Delivery of IGF-1 in the Spinal Cord of a Mouse Model of ALS after Intraparenchymal Injection of an Adeno-Associated Vector
Christine Haenggeli, Angelo C. Lepore, Natalie Perez, Brian K. Kaspar and Jeffrey D. Rothstein
Mol Ther 13: S94-S94; doi:10.1016/j.ymthe.2006.08.272
246. Efficient Gene Transfer to Peripheral Nervous System Via Systemic Delivery of AAV Vectors
Chunping Qiao, Jianbin Li, Tong Zhu, Bing Wang, Juan Li, and Xiao Xiao
Mol Ther 13: S94-S94; doi:10.1016/j.ymthe.2006.08.273
247. Devising A|[beta]|-Specific Passive Immunization Strategies for Alzheimer's Disease Using rAAV Vector-Mediated scFv Antibody Delivery
Kelly L. Fowlkes, Michael A. Mastrangelo, Wade C. Narrow, Yona Levites, Todd E. Golde, Howard J. Federoff and William J. Bowers
Mol Ther 13: S94-S95; doi:10.1016/j.ymthe.2006.08.274
248. Revealing the Role(s) of TNF-alpha in Early Alzheimer's Disease Via rAAV-Mediated Hippocampal Gene Transfer in a Triple Transgenic Mouse Model
Michelle C. Janelsins, Michael A. Mastrangelo, Keigan M. Park, Kelly L. Fowlkes, Maria Kinsky, Wade C. Narrow, Salvatore Oddo, Frank M. LaFerla, Howard J. Federoff and William J. Bowers
Mol Ther 13: S95-S95; doi:10.1016/j.ymthe.2006.08.275
249. Fusion Intrabodies as Anti-Huntington Gene Therapy
Julie McLear, Jack Webster, Nikolas Webster and Anne Messer
Mol Ther 13: S95-S95; doi:10.1016/j.ymthe.2006.08.276
250. Protection Against Huntington's Diease Progression: AAV-Mediated Delivery of Biotherapeutics
Adrian P. Kells, Rebecca A. Henry, Stephanie M. Hughes, Richard L.M. Faull and Bronwen Connor
Mol Ther 13: S95-S96; doi:10.1016/j.ymthe.2006.08.277
251. Gene-Based Interferon-Beta Therapy for Experimental Autoimmune Encephalomyelitis
Ritika Jaini, Drew Hannaman, Justin M. Johnson, Robert M. Bernard, Cengiz Z. Altuntas, Maida M. de las Alas, Pavani Kesaraju, Alain Luxembourg, Claire F. Evans and Vincent K. Tuohy
Mol Ther 13: S96-S96; doi:10.1016/j.ymthe.2006.08.278
252. Targeted Transgene Integration of the Human ATM cDNA Mediated by HSV/AAV Hybrid Amplicon Vector
Jocelyn D. Sanford, Angelika Oehmig, Katherine F. Perry, Xandra O. Breakefield and Maria L. Cortes
Mol Ther 13: S96-S96; doi:10.1016/j.ymthe.2006.08.279
253. AAV Delivery of a Trans-Splicing RNA Re-Directs SMN2 Splicing and Results in Increased Full-Length SMN
Tristan H. Coady, Monir Shababi and Christian L. Lorson
Mol Ther 13: S97-S97; doi:10.1016/j.ymthe.2006.08.280
254. Protecting the CNS Using AntiOxidant Gene Transfer: HIV-1 Glycoprotein gp120 Induces Blood-Brain Barrier Abnormalities That May Be Prevented by rSV40 Gene Transfer of AntiOxidant Enzymes
Jean-Pierre Louboutin, Beverly A.S. Reyes, Lokesh Agrawal, Elisabeth J. van Bockstaele and David S. Strayer
Mol Ther 13: S97-S97; doi:10.1016/j.ymthe.2006.08.281
255. Preventing In Vivo Neurotoxicity Caused by HIV-1 Gp120 Using SV40 Vector Delivery of the Anti-Oxidant Enzymes Superoxide Dismutase and Glutathione Peroxidase
Lokesh Agrawal, Jean-Pierre Louboutin, Beverly A.S. Reyes, Elisabeth Van Bockstaele and David S. Strayer
Mol Ther 13: S97-S98; doi:10.1016/j.ymthe.2006.08.282
256. Novel Therapeutic Strategy for Ischemic Stroke by Bone Marrow Stromal Cells and Ex Vivo HGF and FGF2 Genes Transfer with Replication-Incompetent HSV-1 Vector
Naosuke Nonoguchi, Ming-Zhu Zhao, Naokado Ikeda, Yoshihito Miki, Daisuke Furutama, Fumiharu Kimura, Mari Dezawa, Hiroshi Funakoshi, Robert S. Coffin, Shin-ichi Miyatake and Toshihiko Kuroiwa
Mol Ther 13: S98-S98; doi:10.1016/j.ymthe.2006.08.283
257. VEGF Gene Transfered Bone Marrow Stromal Cells by Replication-Deficiet Herpes Simplex Virus Type-1 (HSV-1) Vector Can Improve the Neurological Deficits and Reduce the Infaction in Rat Ischemic Brain
Yoshihito Miki, Naosuke Nonoguchi, Naokado Ikeda, Ming-Zhu Zhao, Daisuke Furutama, Robert S. Coffin, Naosuke Nonoguchi and Shin-ichi Miyatake
Mol Ther 13: S98-S99; doi:10.1016/j.ymthe.2006.08.284
258. CNS-Directed Antioxidant Enzyme Delivery: Protecting Neurons from Oxidative Stress and Apoptosis Induced by HIV-1
Lokesh Agrawal, Jean-pierre Louboutin and David S. Strayer
Mol Ther 13: S99-S99; doi:10.1016/j.ymthe.2006.08.285
259. Plasmid DNA Encoding the Anti-Inflammatory Cytokine Gene, Interleukin-10 (IL-10) for Chronic Pain Control: Taking Advantage of Nuclear Scaffold/Matrix Attachment Regions
Erin D. Milligan, Stephen J. Langer, Travis S. Hughes, Evan M. Sloane, John H. Mahoney, Brian M. Jekich, Steven F. Maier, Leslie A. Leinwand and Linda R. Watkins
Mol Ther 13: S99-S99; doi:10.1016/j.ymthe.2006.08.286
260. ITRs Necessary for IL-10 Encoding Naked Plasmid Induced Reversal of Chronic Pain State in Rat
T.S. Hughes, S.J. Langer, E.M. Sloane, J. Mahoney, B. Jekich, K.W. Johnson, R.E. Chavez, E.D. Milligan, L.R. Watkins and L.A. Leinwand
Mol Ther 13: S100-S100; doi:10.1016/j.ymthe.2006.08.287
261. In Vivo Over-Expression of Fractalkine, a Putative Neuron-to-Glia Signal, To Characterize Underlying Mechanisms of Neuropathic Pain
Stephen J. Langer, David Busha, Erin D. Milligan, Travis S. Hughes, Julie Wieseler-Frank, Linda R. Watkins and Leslie A. Leinwand
Mol Ther 13: S100-S100; doi:10.1016/j.ymthe.2006.08.288
262. Delivery of CCL21 to Metastatic Disease Improves the Efficacy of Adoptive T Cell Therapy
Uma Thanarajasingam, Laura Sanz Alcober, Rosa Maria Diaz, Jian Qiao, Luis Sanchez-Perez, Timothy Kottke, Jill Thompson and Richard Vile
Mol Ther 13: S100-S101; doi:10.1016/j.ymthe.2006.08.316
263. Antigen-Specific and MHC-Independent Tumor Cell Lysis by Redirected Human CD4+ T Cells Grafted with an Antibody-Type Immunoreceptor
Andreas Hombach, Heike Koehler, Gunter Rappl and Hinrich Abken
Mol Ther 13: S101-S101; doi:10.1016/j.ymthe.2006.08.317
264. Immune Gene-Therapy of Cancer Using Redirected Na|[iuml]|ve or Effector Lymphocytes
Dinorah Friedmann-Morvinski, Tova Waks and Zelig Eshhar
Mol Ther 13: S101-S101; doi:10.1016/j.ymthe.2006.08.318
265. Non-Viral Delivery of Interleukin-2 and Soluble Flk-1 Inhibits Metastatic and Primary Tumor Growth in Renal Cell Carcinoma
James W. Yockman, Won Jong Kim, Chien-Wen Chang and Sung Wan Kim
Mol Ther 13: S101-S101; doi:10.1016/j.ymthe.2006.08.319
266. Gene Modification of T Antigen Presenting Cells for the Induction of Antitumor Immunity
Aaron E. Foster, Ann M. Leen, Timothy Lee, Juan Vera, Gianpietro Dotti and Cliona M. Rooney
Mol Ther 13: S101-S102; doi:10.1016/j.ymthe.2006.08.320
267. Synergistic Antitumor Effect of neu DNA Vaccine and Low Dose of Geldanamycin
Chi-Chen Lin, Meng-Chi Yen and Ming-Derg Lai
Mol Ther 13: S102-S102; doi:10.1016/j.ymthe.2006.08.321
268. CD19-Targeted Normal and CLL Patient T Cells Expanded with Beads Can Eradicate Systemic Tumors In Vivo
J. Stefanski, R. Brentjens, D. Hollyman, M. Bonyhadi, M. Sadelain and I. Rivi|[egrave]|re
Mol Ther 13: S102-S102; doi:10.1016/j.ymthe.2006.08.322
269. Integrated CD28 and 4-1BB Signals Strongly Potentiate CD8+ T Cell Mediated radication of Metastatic Prostate Cancer
Xiao-Song Zhong, Maiko Matsushita, Aurore Saudemont, Elmer Santos and Michel Sadelain
Mol Ther 13: S103-S103; doi:10.1016/j.ymthe.2006.08.323
270. The RheoSwitch|[reg]| Therapeutic System Precisely Regulates IL-2 Expression in Melanoma Cells and Supports Survival of NK Cells at the Tumor Site
Anand K. Katakam, Qin Yang, Steve Goding, Prasanna Kumar and Per H. Basse
Mol Ther 13: S103-S103; doi:10.1016/j.ymthe.2006.08.324
271. Full-Length Antibody Therapy Mediated by Adenovirus in Rodent and Non-Primate Animal Models
Wenfang Shi, Jie Chen, Minghong Jiang, Changqing Su and Qijun Qian
Mol Ther 13: S104-S104; doi:10.1016/j.ymthe.2006.08.325
272. Conversion of a Tumor-Binding Peptide Identified by Phage Display to a Functional Chimeric T-Cell Antigen Receptor
Colette R.J. Pameijer, Araceli Hamlett, Bessie Meechovet, Jamie Buckmaster, Brenda Aguilar, Christine Wright, Wen- Chung Chang, Christine E. Brown and Michael C. Jensen
Mol Ther 13: S104-S104; doi:10.1016/j.ymthe.2006.08.326
273. Immuno Gene Therapy of Feline Fibrosarcoma Using Intratumoral Magnetofection or Gene-Activated Matrices for Gene Delivery |[ndash]| Preliminary Results of a Veterinary Clinical Study
Ulrike Schillinger, Bianca Schwarz, Tina Kempf, Anika Jahnke, Cornelia Fischer, Anne Loecher, Stefanie Schlemmer, Johannes Hirschberger, Thomas Brill, Roberto Koestlin, Bernd Gaensbacher and Christian Plank
Mol Ther 13: S105-S105; doi:10.1016/j.ymthe.2006.08.327
274. Antitumor Effect of Controlled Expression of Interleukin-12 in a Murine Model of Liver Metastases
Itsaso Mauleon, Julien Crettaz, Gloria Gonzalez-Aseguinolaza, Maider Zabala, Gabriela Kramer, Stephan Kochanek, Jesus Prieto and Ruben Hernandez-Alcoceba
Mol Ther 13: S105-S105; doi:10.1016/j.ymthe.2006.08.328
275. Immunostimulatory Antigen Loaded Microparticles as Cancer Vaccines
Aliasger K. Salem, Anthony D. Sandler, George J. Weiner, Xueqing Zhang, Nicki K. Baman, Xiaoyan Zhu and Christopher E. Dahle
Mol Ther 13: S105-S105; doi:10.1016/j.ymthe.2006.08.329
276. Phase I Trial of Sequential Administration of Recombinant DNA and Adenovirus Expressing L523S Protein in Early Stage Non Small Cell Lung Cancer (NSCLC)
John Nemunaitis, Thomas Meyers, Neil Senzer, Casey Cunningham, Howard West, Eric Vallieresma, Stephen Anthony, Svetislava Vukelja, Barry Berman, Heather Tully, Beena Pappen, Stephen Sarmiento, Rosemarie Arzaga, Steven Duniho, Susan Engardt, Madeleine Meagher and Martin Cheever
Mol Ther 13: S106-S106; doi:10.1016/j.ymthe.2006.08.330
277. Clinical Evaluation of Dendritic Cell Vaccination for Patients with Recurrent Glioma: Results of a Clinical Phase I/II Trial
Ryuya Yamanaka, Junpei Homma, Naoki Yajima, Masakazu Sano and Masuhiro Takahashi
Mol Ther 13: S106-S106; doi:10.1016/j.ymthe.2006.08.331
278. Therapeutic Activities of IL-12 Gene- Modified Macrophages Embedded in Gelatin Matrix Hemostatic Sealant (FloSeal|[reg]|) in a Mouse Model of Residual Prostate Cancer
Ken-ichi Tabata, Masami Watanabe, Takefumi Satoh, Wei-hau Tian, Hongyu Wang, ElMoataz Abdel Fattah, Guang Yang, Daniel Floryk, Dov Kadmon and Timothy C. Thompson
Mol Ther 13: S106-S106; doi:10.1016/j.ymthe.2006.08.332
279. Eradication of Renal Cell Carcinoma in Mice Mediated by NK Cell Activation Using Inactivated Sendai Virus Particle (HVJ-E)
Atsuko Fujihara, Masayuki Kurooka, Tsuneharu Miki and Yasufumi Kaneda
Mol Ther 13: S107-S107; doi:10.1016/j.ymthe.2006.08.333
280. RANTES and TARC Enhanced the Antitumor Immune Effects of GM-CSF
Hiroyuki Inoue, Takafumi Nakamura, Meng Xin, Yoshito Beppu, Gaku Sakaguchi, Ryo Kurita, Hidenori Hase, Yukoh Nakazaki, Yoshikazu Yonemitsu, Koichi Takayama, Yoichi Nakanishi, Yusuke Nakamura, Shigetaka Asano and Kenzaburo Tani
Mol Ther 13: S107-S107; doi:10.1016/j.ymthe.2006.08.334
281. Adenovirus-Mediated CD40 Ligand Therapy Induces Tumor Cell Apoptosis and Systemic Immunity in the TRAMP-C2 Mouse Prostate Cancer Model
Helena Dzojic, Angelica Loskog, Thomas Totterman and Magnus Essand
Mol Ther 13: S107-S107; doi:10.1016/j.ymthe.2006.08.335
282. Antitumor Efficacy of Intravenous Administration of Oncolytic Herpes Simplex Virus Expressing Interleukin 12
Yi Guan, Yasushi Ino, Hiroshi Fukuhara and Tomoki Todo
Mol Ther 13: S108-S108; doi:10.1016/j.ymthe.2006.08.336
283. DNA Vaccination with Genes Encoding an Antigenic Protein and Fas Ligand Increased Antigen-Specific Humoral Responses
Osamu Shimozato, Ayako Sato, Kiyoko Kawamura, Quanhai Li, Guangyu Ma and Masatoshi Tagawa
Mol Ther 13: S108-S108; doi:10.1016/j.ymthe.2006.08.337
284. Reduced Lung Metastasis of Secreted Type of Substance P Gene Modified Mouse Melanoma Cells
Xianghui He, Zhixiang Zhang, Liwei Zhu, Tom C. Tsang and David T. Harris
Mol Ther 13: S108-S108; doi:10.1016/j.ymthe.2006.08.338
285. Concanavalin A That Bears Direct Cytotoxicity and Immunomodulating Activity Via Mannose-Specific Cellular Binding Has Therapeutic Effect in a Murine In Situ Hepatoma Model
Chih-Peng Chang, Ying-Tai Jin and Huan-Yao Lei
Mol Ther 13: S109-S109; doi:10.1016/j.ymthe.2006.08.339
286. Biodistribution and Cearance Following Intraperitoneal Injection of Murine Interleukin-12 Plasmid Formulated with a Novel Polymeric Delivery System
Elaine Brunhoeber, Majed Matar, Khursheed Anwer and Jason G. Fewell
Mol Ther 13: S109-S109; doi:10.1016/j.ymthe.2006.08.340
287. Safety and Toxicity Following Intraperitoneal Injection of Murine Interleukin-12 Plasmid Formulated with a Novel Polymeric Delivery System
Jason G. Fewell, Jennifer Rice, Majed Matar and Khursheed Anwer
Mol Ther 13: S109-S109; doi:10.1016/j.ymthe.2006.08.341
288. Bi-Modality Induction of TNF|[alpha]|: Neoadjuvant Chemoradiotherapy and TNFerade|[trade]| in Patients with Locally Advanced, Resectable Esophageal Carcinoma
Neil Senzer, Kenneth Chang, Stephen Swisher, Tony Reid, Ann Mauer, Amitabh Chak, Harlan Pinto and John Nemunaitis
Mol Ther 13: S110-S110; doi:10.1016/j.ymthe.2006.08.343
289. Adenoviral-Mediated p53 Gene Therapy (Advexin) in a Patient with Li-Fraumeni Syndrome with a Mixed Germ Cell Tumor: Tolerability and Response
Neil Senzer, Jeffrey Lamont and John Nemunaitis
Mol Ther 13: S110-S110; doi:10.1016/j.ymthe.2006.08.344
290. Prolegomenon to a Phase II Study of an ICP34.5/ICP47 Deleted Herpes Simplex Virus Containing the Coding Sequence for GM-CSF in Patients with Melanoma
Neil Senzer and John Nemunaitis
Mol Ther 13: S110-S110; doi:10.1016/j.ymthe.2006.08.345
291. In Vivo Characterization of Seneca Valley Virus (SVV-001), a Novel Oncolytic Picornavirus for Systemic Treatment of Patients with Solid Tumors with Neuroendocrine Features
Kevin D. Burroughs, Kristine Skele, Christian Sherk, Brian Jones, Ann-Jeanette Vasko, Laura Hales, Seshidhar R. Police and Paul L. Hallenbeck
Mol Ther 13: S111-S111; doi:10.1016/j.ymthe.2006.08.346
292. Polyethylenimine Mediated Oral Cancer Targeted PUMA Gene Delivery Suppressed Tumor Growth and Prolonged Survival
Benson Chen, Ming-Shyan Huang, Steven Yeh, Mark Y.P. Kuo and Michael Hsiao
Mol Ther 13: S111-S111; doi:10.1016/j.ymthe.2006.08.347
293. Sustained Expression of Kringle 1 Domain of Human Hepatocyte Growth Factor (HGFK1) Effectively Inhibits Angiogenesis, Growth and Metastasis of Hepatocellular Carcinoma
Zan Shen, Zhen Fan Yang, Yi Gao, Ching Chiu Liu, Samuel S. Ng, Sheung Tat Fan, Ming-liang He, Tsai-ping Li, Ren-bao Gan, Hsiang-fu Kung and Marie Chia-mi Lin
Mol Ther 13: S111-S112; doi:10.1016/j.ymthe.2006.08.348
294. The Histone Deacetylase Inhibitor FK228 Increases Histone Acetylation, Coxsackie Adenovirus Receptor Levels and Adenovirus Transgene Expression in Human LOX IMVI Melanoma Xenografts
Merrill E. Goldsmith, Kenneth Steadman, Alian Aguila, Michael C. Alley, William R. Waud, Susan Bates and Tito Fojo
Mol Ther 13: S112-S112; doi:10.1016/j.ymthe.2006.08.349
295. Effects of Sustained Anti-Angiogenic Gene Therapy in Multi-Stage Prostate Cancer in TRAMP Mice
Tatyana Isayeva, Diptiman Chanda and Selvarangan Ponnazhagan
Mol Ther 13: S112-S112; doi:10.1016/j.ymthe.2006.08.350
296. Transgene Expression and Neutralizing Antibody Production after Submandibular Gland Administration of AdhAQP1
Corinne M. Goldsmith, Changyu Zheng, Molly Vallant, Richard D. Irwin and Bruce J. Baum
Mol Ther 13: S113-S113; doi:10.1016/j.ymthe.2006.08.351
297. Safety of Repeat Intracerebral Administration of MV-CEA in Rhesus Macaques in Support of a Phase I/II Clinical Trial for Patients with Recurrent Gliomas
Rae M. Myers, Mary E. Harvey, Suzanne M. Greiner, Diane C. Soeffker, James W. Krempski, Paula J. Zollman, Steven E. Shelton, Raffel Corey, Goerss J. Stephan, Kaufmann J. Timothy, Federspiel J. Mark, Peng Kah-Whye, Russell J. Stephen and Galanis Evanthia
Mol Ther 13: S113-S113; doi:10.1016/j.ymthe.2006.08.352
298. Combination Effect of Telomerase-Specific Replication-Competent Adenovirus (Telomelysin, OBP-301) and p53 Gene Therapy in Human Non- Small Cell Lung and Colon Cancer Cells
Ryo Sakai, Fuminori Teraishi, Toru Kojima, Yoshihiro Ikeda, Masayoshi Hioki, Toshiya Fujiwara, Futoshi Uno, Shunsuke Kagawa, Yuuri Hashimoto, Yuichi Watanabe, Yasuo Urata, Noriaki Tanaka and Toshiyoshi Fujiwara
Mol Ther 13: S114-S114; doi:10.1016/j.ymthe.2006.08.353
299. In Vivo Luciferase Imaging for Analysis of Oncolytic Adenoviruses for Renal Cell Cancer
Kilian Guse, Tuuli Ranki, Tanja Hakkarainen, Martti Ala- Opas, Tommi Pisto, Merja S|[auml]|rkioja, Maria Rajecki, Anna Kanerva and Akseli Hemminki
Mol Ther 13: S114-S114; doi:10.1016/j.ymthe.2006.08.354
300. Gene Therapy for Gastric Cancer Cells Via CEA-Targeted Adv-FZ33
Toshihiro Tanaka, Jianhua Huang, Sachie Hirai, Motomu Kuroki, Masahide Kuroki, Naoki Watanabe, Kazunori Kato and Hirofumi Hamada
Mol Ther 13: S114-S115; doi:10.1016/j.ymthe.2006.08.355
301. Safe and Effective Treatment of Ovarian Cancer Models Using Targeted Adenovirus Vector Delivery and Selective Expression of Tumor Necrosis Factor
Selva R. Murugesan, Masaki Akiyama, David A. Einfeld, Thomas J. Wickham and C. Richter King
Mol Ther 13: S115-S115; doi:10.1016/j.ymthe.2006.08.356
302. Anti-Angiogenic Treatment Enhances Anti- Tumor Effects of an Oncolytic Virus in an Experimental Rat Glioma Model
Kazuhiko Kurozumi, Jennifer Cutter, William Carson, Ming Yang, Gregory Christoforidis, Antonio E. Chiocca and Balveen Kaur
Mol Ther 13: S115-S116; doi:10.1016/j.ymthe.2006.08.357
303. Enhanced Antitumor Efficacy of Telomerase-Selective Oncolytic Adenoviral Agent OBP-401 with Docetaxel: Preclinical Evaluation of Chemovirotherapy
Yoshihiro Ikeda, Toshiya Fujiwara, Shunsuke Kagawa, Masayoshi Hioki, Ryo Sakai, Toru Kojima, Yasuo Urata, Noriaki Tanaka and Toshiyoshi Fujiwara
Mol Ther 13: S116-S116; doi:10.1016/j.ymthe.2006.08.358
304. Therapeutic Efficacy of a Mesothelin Promoter-Based Conditionally Replicative Adenovirus Monitored by In Vivo Imaging of an Ovarian Cancer Model
Yuko Tsuruta, Larisa Pereboeva, Martina Breidenbach, Daniel T. Rein, Masaharu Nakayama, Gene P. Siegal and David T. Curiel
Mol Ther 13: S116-S116; doi:10.1016/j.ymthe.2006.08.359
305. Targeting the Gene and the Derived Gene- Product into Tumors
Shulin Li, Ryan Craig and Marina Torrero
Mol Ther 13: S117-S117; doi:10.1016/j.ymthe.2006.08.360
306. Imaging HSV-1 Viral Oncolysis of Colon Cancer Cells by microPET
Darshini Kuruppu, Aijun Zhu, Meixiang Yu, Anna-Liisa Brownell and Kenneth K. Tanabe
Mol Ther 13: S117-S117; doi:10.1016/j.ymthe.2006.08.361
307. Prostate Targeted TSTA Oncolytic Adenovirus
Makoto Sato, Steve Huyn, Russell Powell, Michael Carey, Sanjiv S. Gambhir and Lily Wu
Mol Ther 13: S117-S118; doi:10.1016/j.ymthe.2006.08.362
308. Valproic Acid, a Histone Deacetylase Inhibitor, Is an Antagonist for Oncolytic Adenoviral Gene Therapy
Naser Uddin Hoti, Shawn E. Lupold, Wasim Chowdhury, Jer-Tsong Hsieh and Ronald Rodriguez
Mol Ther 13: S118-S118; doi:10.1016/j.ymthe.2006.08.363
309. Oncolytic Efficacy and Enhanced Safety of Measles Virus Activated by Tumor-Secreted Matrix-Metalloproteases
Christoph Springfeld, Veronika von Messling, Marie Frenzke, Guy Ungerechts, Christian Buchholz and Roberto Cattaneo
Mol Ther 13: S118-S118; doi:10.1016/j.ymthe.2006.08.364
310. Antitumor Effect of Telomerase-Specific Virotherapy in Pleural Dissemination of Human Malignant Mesothelioma
Yuichi Watanabe, Yuuri Hashimoto, Toru Kojima, Shunsuke Kagawa, Hitoshi Kawamura, Katsuyuki Nagai, Noriaki Tanaka, Yasuo Urata and Toshiyoshi Fujiwara
Mol Ther 13: S118-S118; doi:10.1016/j.ymthe.2006.08.365
311. Target-Specific Knockdown and Enhanced Anti-Tumor Outcome by an Oncolytic Virus- Delivered Small Interfering RNA (siRNA)
Alex W. Tong, Yu-An Zhang, Shirley Samuel, Patrick Chen, Yuqiao Shen and John Nemunaitis
Mol Ther 13: S118-S119; doi:10.1016/j.ymthe.2006.08.366
312. Clearance of Helper Adenovirus by an AAV1 Clinical Vector Manufacturing Process
Barb Thorne, Paulene Quigley, Gina Nichols, David Price, Christine Moore, Kristin Parker, Tsering Sangmo, Eric Pastor, Morgan Peterson, Ryan Takeya and Richard Peluso
Mol Ther 13: S119-S119; doi:10.1016/j.ymthe.2006.08.368
313. Cell Type Specific Media Optimization for Clinical Retroviral Transduction Protocols
J. Stefanski, O. Borquez-Ojeda, T. Budak-Alpdogan, R. Kendle, M. Przybylowski, D. Hollyman, M. Sadelain and I. Rivi|[egrave]|re
Mol Ther 13: S119-S120; doi:10.1016/j.ymthe.2006.08.369
314. Developing Gene Transfer Vectors for Cancer Therapy: Identifying and Overcoming Regulatory Challenges
Rosemarie Aurigemma
Mol Ther 13: S120-S120; doi:10.1016/j.ymthe.2006.08.370
315. Identification and Control of Bacterial Contamination in an Academic Good Manufacturing Practice Facility
Timothy P. O'Connor, Neil R. Hackett, Robert G. Pergolizzi, Dolan Sondhi, Julie L. Boyer, Stephen M. Kaminsky and Ronald G. Crystal
Mol Ther 13: S120-S120; doi:10.1016/j.ymthe.2006.08.371
316. Production of Adenoviral Vectors in an Academic cGMP Facility
M.F. Medina, J. Rudy, U. Sankar, D. Chong, R. Foley and J. Gauldie
Mol Ther 13: S121-S121; doi:10.1016/j.ymthe.2006.08.372
317. Simplified Concentration and Purification of Lentivirus Pseudotypes
Robert H. Kutner, Brian DaLeo and Jakob Reiser
Mol Ther 13: S121-S121; doi:10.1016/j.ymthe.2006.08.373
318. Collaborative Development of an Effective Method To Produce Clinical RNAi Products
Sriram Ramakrishnan, Jeffrey E. Darnell, Gary Gates, Hugo L. Gonzales, Justin Miller and Henry Hebel
Mol Ther 13: S121-S121; doi:10.1016/j.ymthe.2006.08.374
319. Comparison of Serum-Free Media for Optimal Ex Vivo Transduction of Human CD34+ Cells
Joanna L. Ireland, Greg M. Podsakoff, Donald B. Kohn and Barbara C. Engel
Mol Ther 13: S122-S122; doi:10.1016/j.ymthe.2006.08.375
320. Modeling Human Brain Cancer in Transgenic E2F1 Mice
Melissa V. Olson, Kenneth D. Aldape, Gregory N. Fuller, Marta M. Alonso, Candelaria Gomez-Manzano, Johnson G. David and Fueyo Juan
Mol Ther 13: S122-S122; doi:10.1016/j.ymthe.2006.08.377
321. Sea Urchin sns Chromatin Insulator Prevents Silencing and Positional Effect Variegation of Oncoretroviral Vectors Transgene Expression in Murine Erythroid Cell Line
Danilo D'Apolito, Santina Acuto, Rosalba Di Marzo, Mariella Bagliesi, Valentina Motta, Elena Baiamonte, Roberta Calzolari, Vito Franco, Giovanni Spinelli and Aurelio Maggio
Mol Ther 13: S122-S123; doi:10.1016/j.ymthe.2006.08.378
322. Syngeneic Cotton Rat Cancer Model for Replicating Adenoviral Vectors
Jason C. Steel, Brian J. Morrison, Poonam Mannan, Gregory A. Prince, Kevin C. Yim, Brian K. Miles, Oliver Wildner and John C. Morris
Mol Ther 13: S123-S123; doi:10.1016/j.ymthe.2006.08.379
323. In Vivo Regulation of rAAV-Mediated GDNF Expression in the Rat Striatum
Corinna Burger, Emily Piercefield, Layla Sullivan, Ronald Mandel and Nicholas Muyczka
Mol Ther 13: S123-S123; doi:10.1016/j.ymthe.2006.08.380
324. Development of Bioluminescence Tomography for Three-Dimensional Real Time Imaging of Gene Expression
Nathalie Y. Toussaint, Lu Yin, Aaron Hirko, Qiang Wang, Qizhi Zhang, Huabei Jiang and Sean Sullivan
Mol Ther 13: S123-S124; doi:10.1016/j.ymthe.2006.08.381
325. In Vitro Gene Knockdown of Rat Pyruvate Dehydrogenase E1 |[alpha]| mRNA by Self- Complementary Adeno-Associated Virus-Mediated Small Interfering RNA Delivery
Zongchao Han, Marina Gorbatyuk, Alfred Lewin, Arun Srivastava and Peter Stacpoole
Mol Ther 13: S124-S124; doi:10.1016/j.ymthe.2006.08.382
326. A Versatile Tool for Conditional Gene Expression and Knockdown
Jolanta Szulc, Maciej Wiznerowicz, Friedrich Beermann, Didier Trono and Patrick Aebischer
Mol Ther 13: S124-S124; doi:10.1016/j.ymthe.2006.08.383
327. Muscle Specific and Efficient Transgene Expression Using the Fast and Slow Troponin I Promoters in Cell Culture
Marilyne Blain, Angela Kumar, Kenneth E. Hastings, George Karpati, Bernard Massie and Renald Gilbert
Mol Ther 13: S125-S125; doi:10.1016/j.ymthe.2006.08.384
328. Transcriptionally Targeted Cancer Gene Therapy for Small Cell Lung Cancer
Nina Pedersen, Thomas T. Poulsen, Mikkel W. Pedersen, Michael S. Lan, Mary B. Breslin and Hans S. Poulsen
Mol Ther 13: S125-S125; doi:10.1016/j.ymthe.2006.08.385
329. Electroporation-Mediated Delivery of Cre- Expressing Plasmids to the Lung Results in Tissue-Specific DNA Excision in Transgenic Mice
Aaron M. Miller and David A. Dean
Mol Ther 13: S125-S126; doi:10.1016/j.ymthe.2006.08.386
330. Effect of Different Inducible Minimal Promoters in the RheoSwitch|[reg]| Therapeutic System That Give Robust and Long-Term In Vivo Gene Expression
Jessica L. Seitzer, Anand Katakam, Marti A. DiPietro, Prasanna Kumar and David W. Potter
Mol Ther 13: S126-S126; doi:10.1016/j.ymthe.2006.08.387
331. Small Fragment Homologous Replacement (SFHR) Modification of Genomic HPRT Occurs in the Presence of Wild-Type p53 in Lymphoblastoid Cells
Babak Bedayat, Alireza Abdolmohammadi, Rosalie Maurisse, Jennifer Shwarz, Judi Cheung, David De Semir, Patric K O'Neill, Janice A. Nicklas and Dieter C. Gruenert
Mol Ther 13: S126-S126; doi:10.1016/j.ymthe.2006.08.388
332. Routes of Ligand Administration That Give Efficient and Robust In Vivo Induction with the RheoSwitch|[reg]| Therapeutic System
Marti A. DiPietro, Jessica L. Seitzer and David W. Potter
Mol Ther 13: S126-S127; doi:10.1016/j.ymthe.2006.08.389
333. Focused Ultrasound-Induced Transgene Activation in Skeletal Muscles
Xiaochun Lu, Georgii Sankin, John Madden and Pei Zhong
Mol Ther 13: S127-S127; doi:10.1016/j.ymthe.2006.08.390
334. A Novel Sequence-Specific Anti-Gene LNA Molecule and Its Comparison to Tail-Clamp bisPNA
Rongbin Ge, Juhana E. Heinonen, Mathias G. Svahn, Abdalla J. Mohamed, Karin E. Lundin and C.I. Edvard Smith
Mol Ther 13: S127-S127; doi:10.1016/j.ymthe.2006.08.391
335. Global Transcriptional Profiles of Murine C2C12 Myoblasts Treated with IGF-1
C. Ramana Bhasker, Shaochun Song and Theodore Friedmann
Mol Ther 13: S127-S127; doi:10.1016/j.ymthe.2006.08.392
336. Impact of Convective Flow on the Cellular Uptake and Transfection Activity of Lipoplex and Adenovirus
Takahiro Fujiwara, Hidetaka Akita, Katsuko Furukawa, Takashi Ushida and Hideyoshi Harashima
Mol Ther 13: S128-S128; doi:10.1016/j.ymthe.2006.08.393
337. Adenoviral Delivery of the RheoSwitch|[reg]| Therapeutic System to Mouse Brain and Liver
David W. Potter, Marti A. DiPietro, Jessica L. Seitzer, Anand Katakam and Prasanna Kumar
Mol Ther 13: S128-S128; doi:10.1016/j.ymthe.2006.08.394
338. Microarray Analysis of Genes Regulated during Induction of Osteogenesis by Human Lim Mineralization Protein-3 (LMP-3) in Human Mesenchymal Stem Cells
Wanda Lattanzi, Camilla Bernardini, Enrico Pola, Andrea Gambotto, Fabrizio Michetti and Paul D. Robbins
Mol Ther 13: S128-S129; doi:10.1016/j.ymthe.2006.08.395
339. FIV Lentiviral Vector Gene Transfer for Hemophilia A
C.P. Chikkanna-Gowda, Litao Xie, Yubin Kang, Melissa A. Hickey, Patrick L. Sinn, Jessica D. Goreham-Voss, Steven W. Pipe and Paul B. McCray Jr.
Mol Ther 13: S129-S129; doi:10.1016/j.ymthe.2006.08.396
340. Cellular Uptake and Subsequent Intracellular of R8-Liposomes Introduced at Low Temperature
Akitada Iwasa, Hidetaka Akita, Ikramy Khalil, Kentaro Kogure, Shiroh Futaki and Hideyoshi Harashima
Mol Ther 13: S129-S129; doi:10.1016/j.ymthe.2006.08.397
341. Lentivirus Transduction of Murine Embryonic Stem Cells with Truncated Human Low-Affinity Nerve Growth Factor Permits Efficient Purification of Genetically Modified Cells without Loss of Stem Cell Characteristics
Ralf-Harto H|[uuml]|bner, Maija Kiuru, Anja Krause, Stefano Rivella, Robert G. Pergolizzi and Ronald G. Crystal
Mol Ther 13: S130-S130; doi:10.1016/j.ymthe.2006.08.399
342. RUNX1 Increases Proliferation of Embryoid Bodies Derived from Human Embryonic Stem Cells
Jenice D'Costa, Alan D. Friedman, Elias Zambidis and Curt I. Civin
Mol Ther 13: S130-S130; doi:10.1016/j.ymthe.2006.08.400
343. Vascular Endothelial Growth Factor Prevents Bone Marrow Derived-Mesenchymal Stem Cell Senescence In Vitro
Jennifer Pons, Hua Su, Yu Huang and Y.W. Kan
Mol Ther 13: S131-S131; doi:10.1016/j.ymthe.2006.08.401
344. AAV Vector-Mediated Msx1 Gene Transfer Induces Hematopoietic Stem/Progenitor Cells in Skeletal Muscle
Masaharu Nobuyoshi, Akihiro Kume, Takashi Matsushita, Hiroaki Mizukami, Takashi Okada, Masashi Urabe, Yuichi Ohgoshi, Takashi Endo and Keiya Ozawa
Mol Ther 13: S131-S131; doi:10.1016/j.ymthe.2006.08.402
345. Hematopoietic Stem-Progenitor Cells Express CD52 mRNA and Membrane Protein
Sebastien Morisot, Robert W. Georgantas III and Curt I. Civin
Mol Ther 13: S131-S132; doi:10.1016/j.ymthe.2006.08.403
346. The ACE System, a Mammalian Artificial Chromosome Engineering Technology: Delivery and Transgene Expression in Human Adult & Embryonic Stem Cells
Sandra L. Vanderbyl, Brent Sullenbarger, Neil MacDonald, Melanie Golembiewski, Carl F. Perez, Harry C. Ledebur Jr and Larry C. Lasky
Mol Ther 13: S132-S132; doi:10.1016/j.ymthe.2006.08.404
347. Expression of the N-Formyl Peptide Receptor in Bone Marrow-Derived Human Mesenchymal Stem Cells
Anand Viswanathan, Richard G. Painter, Nicholas A. Lanson Jr and Guoshun Wang
Mol Ther 13: S132-S132; doi:10.1016/j.ymthe.2006.08.405
348. Kruppel-Like Factor 4 Regulates Proliferation of Human and Mouse Hematopoietic Stem-Progenitor Cells, but Is Not Essential for Mouse Hematopoietic Repopulation
Jonathan K. Alder, Robert W. Georgantas, Richard L. Hildreth and Curt I. Civin
Mol Ther 13: S132-S133; doi:10.1016/j.ymthe.2006.08.406
349. Pretreatment of the Esophagus with Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Complex Increases Migration and Proliferation of Marrow Stem Cell Progenitors of Esophageal Squamous Epithelium
Yunyun Niu, Michael W. Epperly and Joel S. Greenberger
Mol Ther 13: S133-S133; doi:10.1016/j.ymthe.2006.08.407
350. Ectopic Retroviral Expression of LMO2, but Not IL2R|[gamma]|, Blocks Human T-Cell Development from CD34+ Progenitor Cells: Implications for Gene Therapy
Karin Pike-Overzet, Dick de Ridder, Floor Weerkamp, Miranda R.M. Baert, Monique M. Verstegen, Steven J. Howe, Adrian J. Thrasher, Gerard Wagemaker, Jacques J.M. van Dongen and Frank J.T. Staal
Mol Ther 13: S133-S133; doi:10.1016/j.ymthe.2006.08.408
351. Inhibition of Thyroid Hormone Receptors in the Neural Stem Cells of Newborn and Adult Mice In Vivo: Consequences on Target Gene Expression
Zahra Hassani, Gladys Alfama, Jean-Christophe Fran|[ccedil]|ois, Carinne Giovannangeli and Barbara A. Demeneix
Mol Ther 13: S134-S134; doi:10.1016/j.ymthe.2006.08.409
352. CD34+ Hematopoietic Stem-Progenitor Cell MicroRNA Expression and Function: The miR Circuit Diagram of Differentiation Control
Robert W. Georgantas, Richard L. Hildreth, John Alder, Carlo Croece, George A. Calin and Curt I. Civin
Mol Ther 13: S134-S134; doi:10.1016/j.ymthe.2006.08.410
353. Biological Comparison of Mesenchymal Stem Cells Derived from Bone Marrow and Adipose Tissue
Reza Izadpanah, Cynthia Trygg, Christopher Kriedt and Bruce Bunnell
Mol Ther 13: S134-S135; doi:10.1016/j.ymthe.2006.08.411
354. Genetic Modification of Murine Stromal- Derived Cells (MSC) in Suspension Culture as a Model for the Rapid Generation of Transplantable Cytoreagents
Yung-Wei Pan, Tammy Tien Luoh and Peter Kurre
Mol Ther 13: S135-S135; doi:10.1016/j.ymthe.2006.08.412
355. A Platform for Gene Delivery to Embryonic Stem Cells Using HSV
April M. Sunyog, Darren Wolfe, James Wechuck, David Krisky, Ying Jiang and Joseph Glorioso
Mol Ther 13: S135-S135; doi:10.1016/j.ymthe.2006.08.413
356. Engineering of Cell Surface Sialic Acids for Polymeric Gene Delivery
Yihua Loo, S.-Gopalan Sampathkumar, Prabhani U. Atukorale, Kevin J. Yarema and Kam W. Leong
Mol Ther 13: S135-S136; doi:10.1016/j.ymthe.2006.08.414
357. Site-Specific Integration of Immortalization Genes in Human Adult Stem Cells Mediated by DirectIt|[trade]| Recombinases
Anna Tretiakova and Malla Padidam
Mol Ther 13: S136-S136; doi:10.1016/j.ymthe.2006.08.415
358. Lentiviral Vector Integration in Mouse Bone Marrow Stem Cells Undergoing Gene Therapy
Xiaolin Wu, Weijing He, Shawn M. Burgess, Robert A. Clark and Senlin Li
Mol Ther 13: S136-S136; doi:10.1016/j.ymthe.2006.08.416
359. Production of Megakaryocytes and Platelets from Common Marmoset (Callithrix jacchus) ES Cells by Constitutive Expression of tal1/scl Gene
Tomoko Yokoo, Ryo Kurita, Erika Sasaki, Kashiya Takasugi, Hideyuki Imoto, Yoshikuni Tanioka, Yasushi Soda and Kenzaburo Tani
Mol Ther 13: S137-S137; doi:10.1016/j.ymthe.2006.08.417
360. Transmitochondrial Stem Cells: Toward Autologous Cybrid Stem Cell Therapy and Synergistic Transient Regenerative Gene Therapy for Mitochondrial (mt)DNA Diseases
Roger Bertolotti
Mol Ther 13: S137-S137; doi:10.1016/j.ymthe.2006.08.418
361. Lentiviral Vector Transduction Efficiency and Biosafety Profile of Adult Mesenchymal Stem Cells
Barry M. McGrath, Ciara O'Shea, Linda Howard, Mary Murphy, Frank Barry, Timothy O'Brien and Padraig M. Strappe
Mol Ther 13: S137-S138; doi:10.1016/j.ymthe.2006.08.419
Abstracts
362. Evaluation the Effects of MIP-1a on Ex Vivo Expansion of Cord Blood Hematopoietic Progenitor Cells in Different Culture Media
Kamran Alimoghaddam, Mitra Khalili, Massoud Soleimani, Moezi Lili, Panthea Ghodsi, Alireza Arjmand and Ardeshir Ghavamzadeh
Mol Ther 13: S138-S138; doi:10.1016/j.ymthe.2006.08.420
363. Homing of Bone Marrow Cells to the Respiratory Epithelium in a Murine Acute Infection Model
Joanna Rejman and Massimo Conese
Mol Ther 13: S138-S138; doi:10.1016/j.ymthe.2006.08.421
364. The Effect of Overexpression of Vascular Endothelial Growth Factor in Mouse Embryonic Stem Cells on Angiogenesis
Ying Ka Lau and Jennifer L. West
Mol Ther 13: S138-S139; doi:10.1016/j.ymthe.2006.08.422
365. Human Embryonic Stem Cells: Genetic Conversion to the Fanconi Anemia Phenotype
Beiqing Pan and Christopher E. Walsh
Mol Ther 13: S139-S139; doi:10.1016/j.ymthe.2006.08.423
366. Suicide Gene Therapy of Glioma Using Genetically Engineered Human Mesenchymal Stem Cells
Hiroki Namba, Shaoyi Li, Tsutomu Tokuyama, Junkoh Yamamoto and Naoki Yokota
Mol Ther 13: S139-S139; doi:10.1016/j.ymthe.2006.08.424
367. Lentivirus Pseudotyped with Envelope Proteins F and HN from Sendai Virus Transduce Airway Epithelium Efficiency and Persistently
Uta Griesenbach, Katsuyuki Mitomo, Makoto Inoue, Lucinda Somerton, Raymond Farley, Charanjit Singh, Toshiaki Tabata, Yasuji Ueda, Satoshi Fujikawa, Kentaro Washizawa, Mamoru Hasegawa and Eric W.F.W. Alton
Mol Ther 13: S139-S140; doi:10.1016/j.ymthe.2006.08.426
368. Lentiviral Vector Strain of Origin and Target Cell Species-Specific Restriction Factors Influence Transduction Efficiency
Christoph A. Kahl, Paula M. Cannon, Jill Oldenburg and Donald B. Kohn
Mol Ther 13: S140-S140; doi:10.1016/j.ymthe.2006.08.427
369. Development of an Amplifiable Gene Expression System in Lentivirus Vectors
Kit L. Shaw, Karen Pepper, Denise Petersen, Shundi Ge, Gay Crooks and Donald B. Kohn
Mol Ther 13: S140-S140; doi:10.1016/j.ymthe.2006.08.428
370. CRM1 Enhances the Lentiviral Vector Production
Hsin-Lung Lo, Tammy Chang, Paola M. Marcovecchio, Priscilla Yam, John A. Zaia and Jiing-Kuan Yee
Mol Ther 13: S141-S141; doi:10.1016/j.ymthe.2006.08.429
371. Optimization of Feline Immunodeficiency Viral Vectors for RNA Interference
Scott Q. Harper, Patrick D. Staber, Christine Rowley, Sarah Fineberg, Dalyz Ochoa, Colleen Stein and Beverly L. Davidson
Mol Ther 13: S141-S141; doi:10.1016/j.ymthe.2006.08.430
372. Optimizing Foamy Virus Vectors That Inhibit HIV Infection
Jason A. Taylor, Lucia Vojtech, Erik M. Olson, James M. Allen, Grant D. Trobridge, David W. Russell and Robert E. Richard
Mol Ther 13: S141-S142; doi:10.1016/j.ymthe.2006.08.431
373. Targeting the Central Nervous System by Intravenous Administration of a Targeting Lentiviral Vector
Koki Morizono, Yiming Xie, Gene-Errol Ringpis, Nonia Pariente and Irvin S.Y. Chen
Mol Ther 13: S142-S142; doi:10.1016/j.ymthe.2006.08.432
374. Hepatitis Delta Virus-Mediated Amplification of Therapeutic RNAi
Dirk Haussecker, Menashe Elazar, Jeff S. Glenn and Mark A. Kay
Mol Ther 13: S142-S142; doi:10.1016/j.ymthe.2006.08.433
375. A Glaucoma Gene Therapy Model: Eighteen Cat Study Revealing Long-Term Targeted Genetic Modification of the Anterior Chamber by Lentiviral Vectors
Pranay D. Khare, Nils Loewen, Roman Barraza, Michael Fautsch, Douglas Johnson and Eric Poeschla
Mol Ther 13: S142-S143; doi:10.1016/j.ymthe.2006.08.434
376. Hepatic Tropism of Adenoviral Type 5 Vectors Can Be Mediated by Multiple Coagulation Factors
Alan L. Parker, Campbell G. Nicol, Simon N. Waddington, Suzanne M. Buckley, Dmitry M. Shayakhmetov, Shaoheng H. Ni, Andre Lieber, John H. McVey, Laura Denby, Stuart A. Nicklin and Andrew H. Baker
Mol Ther 13: S143-S143; doi:10.1016/j.ymthe.2006.08.436
377. Intravascular Delivery of Adenovirus Vectors Rapidly Targets Platelets to the Reticuloendothelial System
Daniel Stone, Shaoheng Ni, Zong-Yi Li, Dmitry Shayakhmetov and Andre Lieber
Mol Ther 13: S143-S144; doi:10.1016/j.ymthe.2006.08.437
378. Phase I Trial of Intravenous Infusion of Onyx 015 and Enbrel in Solid Tumor Patients
Gerald Edelman, Neil Senzer, Michael Nemunaitis, Casey Cunningham, Paige Sovern, Alex Tong and John Nemunaitis
Mol Ther 13: S144-S144; doi:10.1016/j.ymthe.2006.08.438
379. Identification of Structural Aspects of Adenovirus Interactions with Host Factors In Vivo Using Tandem Mass Spectrometry
Oleksandr Kalyuzhniy, Catalin Doneanu, Martin Sadilek and Dmitry M. Shayakhmetov
Mol Ther 13: S144-S144; doi:10.1016/j.ymthe.2006.08.439
380. Alternative Cellular Receptor for B-Group Adenoviruses: Implications for Gene Therapy
Sebastian Tuve, Hongjie Wang, Anuj Gaggar, Ying Liu and Andre Lieber
Mol Ther 13: S145-S145; doi:10.1016/j.ymthe.2006.08.440
381. The Adenoviral Fiber Shaft Is a Major Determinant of Kupffer Cell Necrosis
Jeffrey S. Smith, Jie Tian, Susan C. Stevenson and Andrew P. Byrnes
Mol Ther 13: S145-S145; doi:10.1016/j.ymthe.2006.08.441
382. The Polysaccharide Mannan as a Novel Chemical Coupling Partner for Adenovirus Vectors with a Potential Use for Genetic Vaccination
Sigrid Espenlaub, Andreas Wortmann, Tatjana Dick, Stefan Kochanek and Florian Kreppel
Mol Ther 13: S145-S146; doi:10.1016/j.ymthe.2006.08.442
383. Polyethylene Glycol Modification of Adenovirus Vectors Reduces Thrombocytopenia through Decreased Platelet Clearance and Activation
Hoyin Mok, Francisca C. Gushkin, Sean Hofherr, Jose A. Lopez and Michael A. Barry
Mol Ther 13: S146-S146; doi:10.1016/j.ymthe.2006.08.443
384. Species B Adenovirus and Hematopoietic Cells Revisited
Goeran Wadell, Anna Segerman, William Burmeister, Steven Cusack, Emma Andersson, Karin Edlund, Praveen Papareddy, Dan Gustafsson, Kristina Lindman, Marko Marttila, Johan Skog, Niklas Arnberg and Ya-fang Mei
Mol Ther 13: S146-S146; doi:10.1016/j.ymthe.2006.08.444
385. Tol2 Transposon as a Gene Therapy Vector: Characterization, Optimization and Correction of Hereditary Tyrosinemia Type 1 in Mouse
Darius Balciunas, Andrew Wilber, Kirk Wangensteen, Jason Bell, Aron Geurts, Perry B. Hackett, David A. Largaespada, R. Scott McIvor and Stephen C. Ekker
Mol Ther 13: S147-S147; doi:10.1016/j.ymthe.2006.08.446
386. Chromosomal Integration Sites of Double-Stranded Linear DNA in Mouse ES Cells
Fumi Ohbayashi and Ko Mitani
Mol Ther 13: S147-S147; doi:10.1016/j.ymthe.2006.08.447
387. Advantageous Properties of the piggyBac Transposon System for Gene Transfer in Human Cells
Matthew H. Wilson, Craig J. Coates, Edward J. Rebar and Alfred L. George Jr.
Mol Ther 13: S147-S148; doi:10.1016/j.ymthe.2006.08.448
388. Chromosomal Rearrangements in Mammalian Cells Are Induced at High Frequency by the Bacteriophage Derived Integrase phiC31
Anja Ehrhardt, Jeffrey A. Engler, Hui Xu, Athena Cherry and Mark A. Kay
Mol Ther 13: S148-S148; doi:10.1016/j.ymthe.2006.08.449
389. Directed Transposon Integration in Human Cells
Stephen R. Yant, Yong Huang, Bassel Akache and Mark A. Kay
Mol Ther 13: S148-S149; doi:10.1016/j.ymthe.2006.08.450
390. Phage c31 Integrase Induces Chromosomal Aberrations in Primary Human Fibroblasts
Jian Liu, Iben Jeppesen, Kate Nielsen and Thomas G. Jensen
Mol Ther 13: S149-S149; doi:10.1016/j.ymthe.2006.08.451
391. De Novo Human Artificial Chromosome Formation Is Predetermined by Initial Chromatin Assembly and Transcriptional Patterns after Transfection
Hiroshi Nakashima, Megumi Nakano, Ryoko Ohnishi, Yasushi Hiraoka, Yasufumi Kaneda, Akio Sugino and Hiroshi Masumoto
Mol Ther 13: S149-S149; doi:10.1016/j.ymthe.2006.08.452
392. Duration of Expression of the Sleeping Beauty Transposase Gene in Mouse Liver Following Hydrodynamic Delivery
Jason B. Bell, Elena L. Aronovich, Brenda L. Koniar, Jeffrey M. Schreifels, Ann M. Clifford, Nathan D. Hoekstra and Perry B. Hackett
Mol Ther 13: S150-S150; doi:10.1016/j.ymthe.2006.08.453
393. Non-Viral Gene Transfer Using the Sleeping Beauty Transposon for Long-Term Gene Expression in the CNS of Neonatal Mice
Zachary L. Demorest, Walter C. Low, Andrew B. Freese and John R. Ohlfest
Mol Ther 13: S150-S150; doi:10.1016/j.ymthe.2006.08.454
394. Neuron-Specific, In Vivo Gene Delivery Mediated by Non-Viral Vectors
In-Kyu Park, Jurate Lasiene, Jennifer M. Knox, Shinn-Huey Chou, Philip J. Horner and Suzie H. Pun
Mol Ther 13: S151-S151; doi:10.1016/j.ymthe.2006.08.456
395. Role of Caveoli on Membrane Raft in the Internalization of Non-Viral Vectors
Peng H. Tan, Maria Manunta and Andrew J.T. George
Mol Ther 13: S151-S151; doi:10.1016/j.ymthe.2006.08.457
396. Quantitative Analysis of Non-Viral Gene Therapy in a Three-Dimensional Liver Bioreactor
Nathan Tedford, Jennifer Fang, Karel Domansky, Linda G. Griffith and Douglas A. Lauffenburger
Mol Ther 13: S151-S152; doi:10.1016/j.ymthe.2006.08.458
397. Compacted DNA Nanoparticles Transfect Cells by Binding to Cell Surface Nucleolin
Xuguang Chen and Pamela B. Davis
Mol Ther 13: S152-S152; doi:10.1016/j.ymthe.2006.08.459
398. Extracellular Matrix Identity and Surface Density Alter Transfection by Complexes Delivered from a Cell-Adhesive Substrate
Zain Bengali and Lonnie D. Shea
Mol Ther 13: S152-S153; doi:10.1016/j.ymthe.2006.08.460
399. Solid Nanobeads Prevents Polycations from Entering the Nuclei and Enhanced Transfection Efficiency
Wenzhong Li, Nan Ma, Leelee Ong, Alexander Kaminski, Peter Lorenz, Brigitte M. P|[uuml]|tzer, Ren-Ke Li, Christof Stamm and Gustav Steinhoff
Mol Ther 13: S153-S153; doi:10.1016/j.ymthe.2006.08.461
400. Peptide-Mediated Gene Transfer of Lipid/ DNA-Based Complexes to Cells Expressing CXC- Receptor 4
Wouter H. Driessen, Nobutaka Fujii, Hirokazu Tamamura and Sean M. Sullivan
Mol Ther 13: S153-S153; doi:10.1016/j.ymthe.2006.08.462
401. Quantitative Bioluminescence Imaging of Transgene Expression In Vivo
Garrett R. Rettig, Marie McAnuff, Dijie Liu, Ji-Seon Kim and Kevin G. Rice
Mol Ther 13: S154-S154; doi:10.1016/j.ymthe.2006.08.463
402. Intracellular Trafficking of QD-FRET Nanoparticles for Gene Delivery
Hunter H. Chen, Yi-Ping Ho, Tza-Huei Wang and Kam W. Leong
Mol Ther 13: S154-S154; doi:10.1016/j.ymthe.2006.08.464
403. Long-Term, High alpha-L-iduronidase Expression in MPS I Dogs Following Neonatal, Intravenous, Retroviral Vector Gene Therapy
Anne Traas, Ping Wang, Xiucui Ma, Patricia O'Donnell, Meg Sleeper, Gus Aguirre, Mark Haskins and Katherine P. Ponder
Mol Ther 13: S154-S155; doi:10.1016/j.ymthe.2006.08.466
404. Therapeutic Correction of PKU in a Mouse Model by Ectopic Expression of PAH and Its BH4- Cofactor Genes in Skeletal Muscle by a Recombinant Triple-Cistronic AAV2-Based Pseudotype 1 Vector
Zhaobing Ding, Cary O. Harding, Alexandre Rebuffat, Lina Elzaouk, Jon A. Wolff and Beat Thony
Mol Ther 13: S155-S155; doi:10.1016/j.ymthe.2006.08.467
405. Correction of the Murine Model of Hereditary Tyrosinemia Type I Using Messenger RNA as a Source of Transposase for Sleeping Beauty Mediated Integration of the FAH Gene
Andrew Wilber, Kirk J. Wangensteen, Yixin Chen, Lijuan Zhou, Joel L. Frandsen, Jason Bell, Zongyu Chen, Stephen C. Ekker, R. Scott McIvor and Xin Wang
Mol Ther 13: S155-S156; doi:10.1016/j.ymthe.2006.08.468
406. rAAV-Mediated Expression of Wnt10b cDNA Prevents the Development of Obesity in DIO Rats
George Aslanidi, Glenn Philipsberg, Vadim Kroutov, Kenneth Lamb, Erik Kohlbrenner, Martha Campbell-Thompson, Glenn Walter, Philip J. Scarpace and Sergei Zolotukhin
Mol Ther 13: S156-S156; doi:10.1016/j.ymthe.2006.08.469
407. A Single Unilateral Injection of AAV1-ASA and AAV1-FGE Vectors into the Hippocampus Results in Bilateral Expression and Widespread Distribution of ASA and Prevention of Sulfatide Storage in the Whole Brain of MLD Model Mice
Toshiyuki Kurai, Sanae Hisayasu, Yukihiko Hirai, Makoto Migita, Hidenori Suzuki and Takashi Shimada
Mol Ther 13: S156-S156; doi:10.1016/j.ymthe.2006.08.470
408. Safety of Lysosomal Enzymes Over-Expression in HSC for Gene Therapy of Storage Disorders
Alessandra Biffi, Ilaria Visigalli, Martina Cesani, Alessia Capotondo, Francesca R. Santoni de Sio, Isabella Pallavicini, Anna Zingale and Luigi Naldini
Mol Ther 13: S157-S157; doi:10.1016/j.ymthe.2006.08.471
409. Complete Correction of Enzymatic Deficiency and Lysosomal Storage throughout the Brain in a Mouse Model of GM1-gangliosidosis after Neonatal Intracerebroventricular Injection of an AAV1 Vector Encoding Lysosomal Acid Beta- galactosidase
Marike L. D. Broekman, Rena Baek, Laryssa A. Comer, Thomas N. Seyfried and Miguel Sena-Esteves
Mol Ther 13: S157-S157; doi:10.1016/j.ymthe.2006.08.472
410. Physiological Correction of Glycogen Storage Disease Type II Using Adeno-Associated Virus Serotype 1 Vectors
Cathryn Mah, Christina A. Pacak, Kerry O. Cresawn, Lara R. DeRuisseau, Sean Germain, Melissa A. Lewis, David D. Fuller and Barry J. Byrne
Mol Ther 13: S158-S158; doi:10.1016/j.ymthe.2006.08.473
411. The Metabolic Basis of Sexual Dimorphism in PKU Mice after PAH Gene Treatment
Li Chen and Savio L.C. Woo
Mol Ther 13: S158-S158; doi:10.1016/j.ymthe.2006.08.474
412. A Novel Friedreich's Ataxia Model and In Vivo Gene Rescue Using HSV-1 Amplicon Vectors in Transgenic Mice
Filip Lim, Gloria Palomo, Christina Mauritz, Alfredo Gimenez, Belen Illana, Francisco Wandosell and Javier Diaz-Nido
Mol Ther 13: S158-S158; doi:10.1016/j.ymthe.2006.08.476
413. Targeting the Low-Density Lipoprotein Receptor on the Blood-Brain Barrier for Transport of |[beta]|-Glucoronidase Can Treat the Neurological Degeneration of MPSVII
Brian J. Spencer and Inder M. Verma
Mol Ther 13: S159-S159; doi:10.1016/j.ymthe.2006.08.477
414. Non-Allele Specific RNA Interference in the CAG140 Knock-In Mouse Model of Huntington's Disease
Jodi L. McBride, Scott Q. Harper, Patrick D. Staber, Ines H. Martins, Haim Burstein, Richard W. Peluso, Barry Polisky, Barrie J. Carter and Beverly L. Davidson
Mol Ther 13: S159-S159; doi:10.1016/j.ymthe.2006.08.478
415. Stimulating Full-Length SMN2 Expression by Delivering Bi-Functional RNAs Via a Viral Vector
Travis D. Baughan, Monir Shababi, Gregory E. Tullis and Christian L. Lorson
Mol Ther 13: S159-S160; doi:10.1016/j.ymthe.2006.08.479
416. Gene Therapy for Parkinsons Disease by In Vivo Plasmid Transfer of Human Hepatocyte Growth Factor in Primate Model
Akihiko Ishida, Hiromi Koike and Ryuichi Morishita
Mol Ther 13: S160-S160; doi:10.1016/j.ymthe.2006.08.480
417. Combination Brain and Systemic Injections of AAV Results in Whole Body Therapy and Extension of Lifespan in the Niemann-Pick Mouse
Marco A. Passini, Jie Bu, Jonathan A. Fidler, Joseph W. Foley, James C. Dodge, Robin J. Ziegler, Wendy W. Yang, Jennifer Clarke, Tatyana V. Taksir, Denise A. Griffiths, Michael A. Zhao, Catherine R. O'Riordan, Lamya S. Shihabuddin, Edward H. Schuchman and Seng H. Cheng
Mol Ther 13: S160-S160; doi:10.1016/j.ymthe.2006.08.481
418. AAV-Mediated sFLT-1 Gene Therapy for Ocular Neovascularization: Longevity, Toxicity and Efficacy Results from Mice and Monkeys
E.P. Rakoczy, C.M. Lai, W.Y. Shen, M. Brankov, N. Barnett, S.Y. Lee, S.G. Leaver, I. Yeo, C.L. Ang and I.J. Constable
Mol Ther 13: S160-S161; doi:10.1016/j.ymthe.2006.08.482
419. Rescue of Cone Photoreceptors after Lentiviral Gene Transfer of Rpe65 cDNA in Knockout Mouse Models of Leber Congenital Amaurosis
Alexis-Pierre Bemelmans, Corinne Kostic, Dana Hornfeld, Meriem Tekaya, Sylvain V. Crippa, William W. Hauswirth, Janis Lem, Mathias Seeliger, Andreas Wenzel and Yvan Arsenijevic
Mol Ther 13: S161-S161; doi:10.1016/j.ymthe.2006.08.483
420. Hydrodynamic Limb Vein Delivery of Naked IGF-1 Plasmid DNA Provides Therapeutic Benefit in SOD1(G93A) Murine ALS Model
Gyula Acsadi, Roumen Anguelov, Xingli Li, Mary Kay Bates, Jon A. Wolff and Hans Herweijer
Mol Ther 13: S161-S161; doi:10.1016/j.ymthe.2006.08.484
421. Killing of Normal Cells Combined with TLR Engagement and CD40 Ligation Generates Autoimmune T Cell Reactivity Sufficient To Treat Large Established Tumors
Luis Sanchez-Perez, Gregory Daniels, Timothy Kottke, Rosa Maria Diaz, Jill Thompson, Heung Chong, Alan Melcher and Richard Vile
Mol Ther 13: S162-S162; doi:10.1016/j.ymthe.2006.08.486
422. Enhancement of Human Monocyte-Derived Dendritic Cell Functions by Adenovirus- Mediated RNA Interference of STAT-3
Tomoko Iwata, Hidetoshi Sumimoto, Hiroyuki Mizuguchi and Yutaka Kawakami
Mol Ther 13: S162-S162; doi:10.1016/j.ymthe.2006.08.487
423. Combination of Sleeping Beauty-Mediated INF-gamma Gene Transfer with CpG Oligodeoxynucleotides Provides Long-Term Survival of Intracranial Glioblastoma in Mice
Anhua Wu, Zachary L. Demorest, Isabelita Vengco, Wei Chen, Walter C. Low, Andrew B. Freese and John R. Ohlfest
Mol Ther 13: S162-S163; doi:10.1016/j.ymthe.2006.08.488
424. Myd88/TLR Signaling Is Required for Immunotherapy-Mediated Glioblastoma Regression
James F. Curtin, Gwendalyn D. King, Marianela Candolfi, Chunyan Liu, Kathrin S. Michelsen, Moshe Arditi, Tamer M. Fakhouri, Begonya Comin-Anduix, Antoni Ribas, Pedro R. Lowenstein and Maria G. Castro
Mol Ther 13: S163-S163; doi:10.1016/j.ymthe.2006.08.489
425. Translation of Enhanced Dendritic Cell Vaccines Using a CID-Inducible CD40 Receptor
Natalia Lapteva, Brent A. Hanks, Jianghong Jiang, Kevin M. Slawin and David M. Spencer
Mol Ther 13: S163-S164; doi:10.1016/j.ymthe.2006.08.490
426. dSLIM Immunomodulators Induce Anti- Tumor Responses Both In Vitro and In Vivo
Manuel Schmidt, Javier Cristobal, Astrid Sander, Bernadette Brzezicha, Sven A. Konig Merediz and Burghardt Wittig
Mol Ther 13: S164-S164; doi:10.1016/j.ymthe.2006.08.491
427. Adenovirus Mediated GRP94/gp96 Expression in Treatment of Neuroblastoma
Shanling Liu, Jiangao Zhu, He Wang, Takashi Kon and Chuan- Yuan Li
Mol Ther 13: S164-S164; doi:10.1016/j.ymthe.2006.08.492
428. Development of an Effective Safety Switch for Selective Elimination of Human T Cells In Vivo after Adoptive Transfer
Tom van Meerten, Henk Rozemuller, Wendy Mackus, Paul Parren, Jan van de Winkel, Marie-Jose Claessen, Rozemarijn van Rijn, Anton Hagenbeek, Anton Martens and Saskia Ebeling
Mol Ther 13: S164-S165; doi:10.1016/j.ymthe.2006.08.493
429. Adenoviral-Mediated Interleukin-15 Receptor-|[alpha]| Gene Therapy of Murine Breast Cancer
Brian J. Morrison, Yutaka Tagaya, Jason C. Steel, Poonam Mannan, Thomas A. Waldmann, John C. Morris and Yoshio Sakai
Mol Ther 13: S165-S165; doi:10.1016/j.ymthe.2006.08.494
430. EGFRvIII Retargeted Oncolytic Measles Virus Strains Have Significant Antitumor Activity Against Gliomas
Cory Allen, Sompong Vongpunsawad, Takafumi Nakamura, C. David James, Mark Schroeder, Roberto Cattaneo, Caterina Giannini, James Krempski, Stephen J. Russell and Evanthia Galanis
Mol Ther 13: S165-S166; doi:10.1016/j.ymthe.2006.08.496
431. Treatment of Multi-Focal CRC Liver Metastases with Repeated Infusion of Oncolytic Vesicular Stomatitis Virus Via the Hepatic Artery
Minoru Yamaki, Katsunori Shinozaki, Savio L.C. Woo and Toshimasa Asahara
Mol Ther 13: S166-S166; doi:10.1016/j.ymthe.2006.08.497
432. Characterization of a Novel Oncolytic Measles Virus Retargeted Against the Urokinase Receptor: In Vitro and In Vivo Studies
Jaime R. Merchan, Caili Tong, Takafumi Nakamura, Ianko Iankov and Stephen J. Russell
Mol Ther 13: S166-S167; doi:10.1016/j.ymthe.2006.08.498
433. Combination Therapy of Androgen-Independent Prostate Cancer Using a Prostate Restricted Replicative Adenovirus and a Replication-Defective Adenovirus Encoding Human Endostatin-Angiostatin Fusion Gene
Xiong Li, Sudhanshu P. Raikwar, You-Hong Liu, Sang-Jin Lee, Yan-Ping Zhang, Shaobo Zhang, Liang Cheng, Sang-Don Lee, Beth Elisa Juliar, Thomas A. Gardner, Meei-Huey Jeng and Chinghai Kao
Mol Ther 13: S167-S167; doi:10.1016/j.ymthe.2006.08.499
434. Oncolytic Virotherapy Using the HSV Mutant rQNestin34.5 towards CD133+ Brain Tumor Stem Cells
Akihiro Otsuki, Ankita Patel, Suzanne Camilli, Kazue Kasai, Sigeru Tanaka, E. Antonio Chiocca and Yoshinaga Saeki
Mol Ther 13: S167-S167; doi:10.1016/j.ymthe.2006.08.500
435. A Fiber-Modified, Relaxin-Expressing Oncolytic Adenovirus Prolongs Survival of Tumor Bearing Mice
Shanthi Ganesh, Melinda VanRoey, Neeraja Idamakanti and Karin Jooss
Mol Ther 13: S167-S168; doi:10.1016/j.ymthe.2006.08.501
436. Coxsackievirus A21 Has Potent Oncolytic Activity in Multiple Myeloma
Elizabeth M. Hadac and Stephen J. Russell
Mol Ther 13: S168-S168; doi:10.1016/j.ymthe.2006.08.502
437. An E1b-19kD-Deleted p53-Expressing Replicating Adenovirus Markedly Enhances the Induction of Apoptosis When Combined with Cisplatin in Head and Neck Cancer Cells
David I. Kutler, Harald Sauthoff, Jin Cheng, Yao Qi Huang, Sheila Heitner, William N. Rom and John G. Hay
Mol Ther 13: S168-S168; doi:10.1016/j.ymthe.2006.08.503
438. Targeting HSV-1 Virions for Specific Binding to Epidermal Growth Factor Receptor-VIII on Tumor Cells
Paola Grandi, Juliet Fernandez, Oscar Szentirmai, Robert Carter, Xandra O. Breakefield and Miguel Sena-Esteves
Mol Ther 13: S168-S168; doi:10.1016/j.ymthe.2006.08.504
439. Genetic Manipulation of Liver Sinusoidal Endothelial Cells (LSEC) and Repopulation of the Mouse Liver with Transplanted LSEC Has Therapeutic Implications
Antonia Follenzi, Daniel Benten, Marco Ulla, Michele De Palma, Phyllis Novikoff and Sanjeev Gupta
Mol Ther 13: S169-S169; doi:10.1016/j.ymthe.2006.08.506
440. Overexpression of Bcl-2 Prevented MSCs from Apoptosis and Improved Heart Function
Nan Ma, Wenzhong Li, Catharina Nesselmann, Leelee Ong, Alexander Kaminski, Brigitte M. P|[uuml]|tzer, Ren-Ke Li, Christof Stamm and Gustav Steinhoff
Mol Ther 13: S169-S169; doi:10.1016/j.ymthe.2006.08.507
441. Stable Oligo-to Polyclonal Hematopoiesis without Clonal Exhaustion Following Extended Reduced Intensity Selection of MGMT-P140K Expressing Murine Repopulating Stem Cells in Serially Transplanted Mice
C.R. Ball, I.H. Pilz, M. Schmidt, M. Schrempp, C. von Kalle and H. Glimm
Mol Ther 13: S169-S170; doi:10.1016/j.ymthe.2006.08.508
442. LV Expressing MR Reporter Genes Allows In Vivo Monitoring of Stem Cell Gene Therapy
Mario Amendola, Letterio S. Politi, Marcello Cadioli, Rossella Galli, Elena Binda, Andrea Falini, Sonia Levi, Giuseppe Scotti, Alessandra Biffi and Luigi Naldini
Mol Ther 13: S170-S170; doi:10.1016/j.ymthe.2006.08.509
443. Successful Long-Term Doxycycline-Regulated Transgene Expression in the Retina of Nonhuman Primates Following Subretinal Injection of Recombinant AAV Vectors
Knut Stieger, Guyl|[egrave]|ne Le Meur, Francoise Lasne, Michel Weber, Jack-Yves Deschamps, Delphine Nivard, Alexandra Mendes-Madeira, Nathalie Provost, Laurent Martin, Philippe Moullier and Fabienne Rolling
Mol Ther 13: S170-S170; doi:10.1016/j.ymthe.2006.08.510
444. Use of dsAAV8-Mediated Gene Transfer to Endogenous |[beta]|-Cells To Investigate the Therapeutic Efficacy of Immunoregulatory Gene Products in Preventing the Onset of Diabetes in NOD Mice
Khaja K. Rehman, Zhong Wang, Xiao Xiao and Paul D. Robbins
Mol Ther 13: S171-S171; doi:10.1016/j.ymthe.2006.08.511
445. Developmental Stage Determines Distribution of Organ Transduction after Intra-Amniotic Injection of Lentiviral Vector
Masayuki Endo, Tiago H. Coelho, Phil W. Zoltick and Alan W. Flake
Mol Ther 13: S171-S171; doi:10.1016/j.ymthe.2006.08.512
446. Inhibition of Hepatic Stellate Cell Activation and Liver Fibrosis by Expression of Cytoglobin In Vivo
Ruian Xu, Phillip Harrison, Xinyan Li, Miao Chen, Hua Li, Pik-to Cheung, Weidong Xiao and Farzin Farzaneh
Mol Ther 13: S171-S172; doi:10.1016/j.ymthe.2006.08.513
447. AP20187-Inducible Insulin-Like Effects in Diabetic Muscle and Liver Transduced with AAV
Gabriella Cotugno, Pietro Formisano, Ferdinando Giacco, Victor M. Rivera, Francesco Beguinot and Alberto Auricchio
Mol Ther 13: S172-S172; doi:10.1016/j.ymthe.2006.08.514
448. Suicide Gene-Mediated Conditional Ablation of Tumors Derived from Transplanted Embryonic Stem Cells
Juyeon Jung, Joanne Kim, Robert G. Pergolizzi and Ronald G. Crystal
Mol Ther 13: S172-S172; doi:10.1016/j.ymthe.2006.08.516
449. Sca-1+ Cell-Based Gene Therapy with a Modified Fibroblast Growth Factor 2 (FGF2) Increased Endosteal/Trabecular Bone Formation in Mice
Susan L. Hall, K.-H. William Lau, Shin-Tai Chen, Matilda H.-C. Sheng, Apurva K. Srivastava, Henry J. Klamut, Jon E. Wergedal, Daila S. Gridley, Subburaman Mohan and David J. Baylink
Mol Ther 13: S173-S173; doi:10.1016/j.ymthe.2006.08.517
450. Novel, Injectable, Genetically Engineered Stem Cell-Based System for Anterior Spinal Fusion
Rod J. Oskouian, Gadi Pelled, Yoram Zilberman, Yamit Tal, Zulma Gazit and Dan Gazit
Mol Ther 13: S173-S174; doi:10.1016/j.ymthe.2006.08.518
451. AAV-BDNF Augments Neurogenesis in Both the Normal Adult Rat Brain and the Quinolinic Acid Lesion Model of Huntington's Disease
Rebecca A. Henry, Stephanie M. Hughes, Richard L.M. Faull and Bronwen J. Connor
Mol Ther 13: S174-S174; doi:10.1016/j.ymthe.2006.08.519
452. Bone Marrow Stem Cells Are Potent Targets for Gene Therapy of Epidermolysis Bullosa, a Genetic Blistering Skin Disease
Katsuto Tamai, TaKehiko Yamazaki, Otsuru Satoru, Takenao Chino, Yasushi Kikuchi and Yasufumi Kaneda
Mol Ther 13: S174-S174; doi:10.1016/j.ymthe.2006.08.520
453. Injectionof Different Adult Cell Types into Mouse Myocardium Three Days after Myocardial Infarction Using a Novel Echo-Guided Technique Improves Cardiac Function
Yan Zhang, Junya Takagawa, Richard E. Sievers, Maelene L. Wong, Christian Heiss, Mohan N. Viswanathan, Neel K. Kapasi, Jianqin Ye, Elyse Foster, William Grossman, Matthew L. Springer and Yerem Yeghiazarians
Mol Ther 13: S175-S175; doi:10.1016/j.ymthe.2006.08.521
454. Recognition of Tumor Antigens by In Vitro Developed T Cells from Hematopoietic Stem Cells Retrovirally Transduced with TCR Genes
Yangbing Zhao, Zhili Zheng, Cyrille J. Cohen, Steven A. Rosenberg and Richard A. Morgan
Mol Ther 13: S175-S175; doi:10.1016/j.ymthe.2006.08.522
455. Genetically Engineered Adult Stem Cells and Hybrid Scaffolds as a Platform for Intervertebral Disc Regeneration
Nadav Kimelman, Rod J. Oskouian, Yoram Zilberman, Gadi Pelled, Zulma Gazit and Dan Gazit
Mol Ther 13: S175-S176; doi:10.1016/j.ymthe.2006.08.523
456. Gene Transfer to Skin Stem Cells by Early Gestational Intra-Amniotic Injection of Lentiviral Vector
Masayuki Endo, Phil W. Zoltick, William H. Peranteau, Mayumi Ito, George Cotsarelis and Alan W. Flake
Mol Ther 13: S176-S176; doi:10.1016/j.ymthe.2006.08.524
457. Reverse Transcriptase Deficient Retroviral Vectors for Transient Cell Modification
Melanie Galla, Axel Schambach, Elke Will and Christopher Baum
Mol Ther 13: S177-S177; doi:10.1016/j.ymthe.2006.08.526
458. Development of Non-Integrating and Site- Specifically Integrating Lentiviral Vectors
Luis Apolonia, Simon Waddington, Mary Collins, Adrian Thrasher and Nicola Philpott
Mol Ther 13: S177-S177; doi:10.1016/j.ymthe.2006.08.527
459. Murine Study To Evaluate Long-Term Transgene Expression of the MSCV-MGMTP140K wc Retroviral Vector in Support of a Phase I Gene Transfer Trial-Limitations of the Murine Model as a Pre-Clinical Tool
Elke Will, Jeff Bailey, Todd Schuesler, Brenden Balcik, Ben Burzynski, David Witte, Gerlinde Layh-Schmitt, Christof vonKalle, Christopher Baum, Brian P. Sorrentino, Lars M. Wagner, Lilith Reeves and David A. Williams
Mol Ther 13: S177-S178; doi:10.1016/j.ymthe.2006.08.528
Abstracts
460. MGMTP140K Vector Constructs for Efficient In Vivo Enrichment of Genetically Corrected Cells Following Hematopoietic Cell Gene Transfer
U.R. Sorg, V. Kleff, G. Nagel, B. Opalka, J. Thomale, B. Kaina and T. Moritz
Mol Ther 13: S178-S178; doi:10.1016/j.ymthe.2006.08.529
461. Evaluation of In Vivo Model Systems for Safety Assessment of HIV-1 Based Lentiviral Vectors
Yuan Zhao, Selina Azam, Kenneth Keating and Robin Thorpe
Mol Ther 13: S178-S178; doi:10.1016/j.ymthe.2006.08.530
462. Comparison of EMCV IRES and FMDV 2A Cleavage Factor for Expression of Canine MGMT and a Second Transgene Using HIV-1 Vectors
Srinivas N. Kumar, Tatiana Zaboikina, Michail Zaboikin and Friedrich G. Schuening
Mol Ther 13: S179-S179; doi:10.1016/j.ymthe.2006.08.531
463. COX-2-Based Gene Therapy: Reduction of Intraocular Pressure in a Glaucoma Gene Therapy Animal Model with Lentiviral Vectors Expressing COX-2, a Prostaglandin Synthase, or a Prostaglandin Receptor
Roman A. Barraza and Eric M. Poeschla
Mol Ther 13: S179-S179; doi:10.1016/j.ymthe.2006.08.532
464. Use of Equine Infectious Anaemia Virus (EIAV) To Mediate Indoleamine 2,3-dioxygenase Gene Transfer to Murine Corneal Allograft Transplantation Model Results in Prolongation of Allograft Survival In Vivo with Little Immunogenicity
Peng H. Tan, Sven C. Beutelspacher and Andrew J.T. George
Mol Ther 13: S179-S180; doi:10.1016/j.ymthe.2006.08.533
465. Pseudotyping Lentiviral Vectors with a Modified GP64 Envelope Proteins Redirects Gene Transfer In Vitro and In Vitro
David Markusic, Niek van Til, Alexander Kanitz, Johan Hiralall, Ronald Oude-Elferink and Jurgen Seppen
Mol Ther 13: S180-S180; doi:10.1016/j.ymthe.2006.08.534
466. Comprehensive Analyses of Diverse Lentiviral and Retroviral Vectors for Post-Entry Restriction by TRIM5|[alpha]| and Implications for Gene Therapy
Dyana T. Saenz and Eric M. Poeschla
Mol Ther 13: S180-S180; doi:10.1016/j.ymthe.2006.08.535
467. Lentiviral Vector (LV) Non-Coding Elements That Impart High Titers and Expression to |[beta]|-Globin (h|[beta]|) Cassettes
F. Urbinati, P. Xia, A. Perumbeti, M. Xia, A. Corsinotti, A. Zarzuela, N. Perelman and P. Malik
Mol Ther 13: S181-S181; doi:10.1016/j.ymthe.2006.08.536
468. Evaluation of Factors Influencing the Production Titers of SIV-Derived Lentiviral Vectors
Nora Naumann, Suk See De Ravin, Morvarid Moayeri, Uimook Choi, Yasuhiro Ikeda and Harry L. Malech
Mol Ther 13: S181-S181; doi:10.1016/j.ymthe.2006.08.537
469. Optimization of the Lentivirus Vector Containing the MSCV-U3 and EF1|[alpha]| Double Internal Promoters
Naoya Uchida, Hideki Hanawa, Motoko Yamamoto and Takashi Shimada
Mol Ther 13: S182-S182; doi:10.1016/j.ymthe.2006.08.538
470. ABCB4 P-Glycoprotein Reduces Infectivity of Lentiviral Particles by Increasing Their Phosphatidylcholine Content
Niek P. van Til, Kirstin Heutinck, Ronald P.J. Oude Elferink and Jurgen Seppen
Mol Ther 13: S182-S182; doi:10.1016/j.ymthe.2006.08.539
471. Chimeric Lentiviral Vectors with Safety Insurance
Kritika Kachapati, Geetanjali Sachdeva and Suresh Arya
Mol Ther 13: S182-S183; doi:10.1016/j.ymthe.2006.08.540
472. Biodistribution of Semliki Forest Virus Vectors and Effect of Preimmunizations in Mice
Juan R. Rodriguez, Erkuden Casales, Jesus Prieto and Cristian Smerdou
Mol Ther 13: S183-S183; doi:10.1016/j.ymthe.2006.08.541
473. Semliki Based Systems for the Production of Retroviral Vectors: A Safety Concern
Eric Piver, Christine Collin, No|[eacute]|mie Renault, Thierry Bru and Jean-Christophe Pages
Mol Ther 13: S183-S183; doi:10.1016/j.ymthe.2006.08.542
474. Deletion of All Membranous Genes of Recombinant Sendai Virus Results in the Dramatic Reduction of Toxicity for Pulmonary Gene Transfer in Neonatal Mice
Sakura Tanaka, Yoshikazu Yonemitsu, Mamoru Hasegawa, Tomoaki Taguchi and Katsuo Sueishi
Mol Ther 13: S184-S184; doi:10.1016/j.ymthe.2006.08.543
475. SeV-Mediated Gene Transfer after Three Re-Administrations in Mice and Sheep
Uta Griesenbach, Gerry McLachlan, Lucinda Somerton, David Collie, Makoto Inoue, Takashi Hironaka, Seng Cheng, Ronald Scheule, Toshiyuki Owaki, Alison Baker, Peter Tennant, Mamoru Hasegawa and Eric W.F.W. Alton
Mol Ther 13: S184-S184; doi:10.1016/j.ymthe.2006.08.544
476. In Vivo Repopulation of Syngenic Hematopoietic Cells Expressing GFP Transfected by Recombinant Sendai Virus |[ndash]| Toward Development of 'Cytoplasmic Gene Therapy' for Hematopoietic Disorders
Kumi Yoshida, Yoshikazu Yonemitsu, Mamoru Haswgawa and Katsuo Sueishi
Mol Ther 13: S185-S185; doi:10.1016/j.ymthe.2006.08.545
477. Replication Deficiency: The Safety Record of a New Sendai Virus Vector Generation
Sascha Bossow, Sabine Schlecht, Marian Wiegand and Wolfgang J. Neubert
Mol Ther 13: S185-S185; doi:10.1016/j.ymthe.2006.08.546
478. Novel Gene Delivery System of Sendai Virus Vector-Transduced Human Peripheral Monocytes
Tomoko Tanaka, Kashiya Takasugi, Ryo Kurita, Takafumi Nakamura, Makoto Inoue, Mamoru Hasegawa, Fumiko Ono, Keiji Terao, Yasuhiro Yoshikawa and Kenzaburo Tani
Mol Ther 13: S185-S186; doi:10.1016/j.ymthe.2006.08.547
479. Development and Characterization of a New Noncytopathic Vector Derived from Semliki Forest Virus
Erkuden Casales, Juan R. Rodriguez-Madoz, Nerea Razquin, Yolanda Cuevas, Jesus Prieto and Cristian Smerdou
Mol Ther 13: S186-S186; doi:10.1016/j.ymthe.2006.08.548
480. Gene Transfer to Gut K Cells for Physiologic Insulin Replacement in Diabetes
Eric C. Hsu, Scott Pownall, Timothy J. Kieffer, Yvonne Luu, Simon Leong, Paul D. Robbins, Xiao Xiao and Anthony T. Cheung
Mol Ther 13: S186-S186; doi:10.1016/j.ymthe.2006.08.549
481. EPIDEMIOLOGY of Seneca Valley Virus (SVV-001), a Novel Oncolytic Picornavirus for the Systemic Treatment of Patients with Solid Cancers with Neuroendocrine Features
Laura M. Hales, Brian H. Jones, Ann-Jeanette Vasko, Nick J. Knowles, Seshidar R. Police and Paul L. Hallenbeck
Mol Ther 13: S187-S187; doi:10.1016/j.ymthe.2006.08.550
482. T Cells as Carriers for Systemic Measles Virotherapy of Multiple Myeloma
Hooi T. Ong, Kosei Hasegawa, Mary Harvey, Allan Dietz, Stephen J. Russell and Kah-Whye Peng
Mol Ther 13: S187-S187; doi:10.1016/j.ymthe.2006.08.551
483. Phenotypic Correction of Von Willebrand Disease Type 3 Blood-Derived Endothelial Cells with Lentiviral Vectors Expressing Von Willebrand Factor
Simon F. DeMeyer, Karen Van hoorelbeke, Marinee K. Chuah, Inge Pareyn, Veerle Gilijns, Robert P. Hebbel, D|[eacute]|sir|[eacute]| Collen and Thierry Vandendriessche
Mol Ther 13: S187-S187; doi:10.1016/j.ymthe.2006.08.552
484. Murine Liver as a Model for AAV Replication, Recombination and Evolution
Xun Sun, You Lu, Gaung-Ping Gao, Michael T. Korn, Julio SanMiguel, Martin W. Lock and James M. Wilson
Mol Ther 13: S187-S188; doi:10.1016/j.ymthe.2006.08.554
485. Long-Term In Vivo Engraftment & Transgene Expression from CD34+ Human Hematopoietic Stem Cells Transduced with Pseudotyped rAAV
Sarah Hardy, Margaret Heerwagen, Lane Bilbrey, Kamehameha K. Wong and Saswati Chatterjee
Mol Ther 13: S188-S188; doi:10.1016/j.ymthe.2006.08.555
486. Efficient and Selective Gene Transfer Directed to Muscle by Tropism-Modified Adeno-Associated Virus Vector
Chi-Yi Yu, Bing Wang, Zhong Wang, Zhongren Cao, Juan Li and Xiao Xiao
Mol Ther 13: S188-S189; doi:10.1016/j.ymthe.2006.08.556
487. Liver-Targeted Gene Therapy in Glycogen Storage Disease Type Ia (GSD-Ia) Requires Widespread, Regulated Glucose-6-phosphatase
Dwight D. Koeberl, Lopamudra Banerjee, Andrew Bird, Baodong Sun and Y.T. Chen
Mol Ther 13: S189-S189; doi:10.1016/j.ymthe.2006.08.557
488. Adeno-Associated Viral Serotype 2/1 Is a Highly Efficient Vector for In Utero Gene Transfer to Hair Cell Precursors
Jeffrey C. Bedrosian, Michael Anne Gratton, John V. Brigande, Waixing Tang and Jean Bennett
Mol Ther 13: S189-S189; doi:10.1016/j.ymthe.2006.08.558
489. Treatment for Hemophilia B Using Self-Complimentary AAV8 Vectors
Micheal L. Hebert, Dirk Grimm, Theresa A. Storm and Mark A. Kay
Mol Ther 13: S189-S190; doi:10.1016/j.ymthe.2006.08.559
490. Successful Readministration of AAV8 Following Administration of Nondepleting CD4 Antibody at the Time of Vector Administration
Jenny H. McIntosh, Melanie Cochrane, Arnold Prizzey, Herman Waldmann, Andrew M. Davidoff and Amit C. Nathwani
Mol Ther 13: S190-S190; doi:10.1016/j.ymthe.2006.08.560
491. Mosaic AAV Vectors Display Novel Properties for Neuronal Transduction
Stanley G. LeRoy, Laryssa A. Comer, Fabricio F. Costa, Marike L.D. Broekman and Miguel Sena-Esteves
Mol Ther 13: S190-S190; doi:10.1016/j.ymthe.2006.08.561
492. Biodistribution and Integration Assessment of AAV1 gag-PR-RT(|[Delta]|RNaseH) after Intramuscular Administration in Rabbits
Bruce C. Schnepp, Michael C. Soult, Tara Allen, Pervin Anklesaria, Philip R. Johnson and Keith Munson
Mol Ther 13: S190-S191; doi:10.1016/j.ymthe.2006.08.562
493. High Efficiency Gene Targeting to Mammalian Joint Tissue Using Self- Complementary Adeno-Associated Viral Vector Serotypes
Laurie R. Goodrich, Vivian W. Choi, Beth C. DudaCarbone, C. Wayne McIlwraith and Richard J. Samulski
Mol Ther 13: S191-S191; doi:10.1016/j.ymthe.2006.08.563
494. Optimizing the Mannitol-Facilitated CNS Entry of Peripherally-Delivered AAV2 Vector
Haiyan Fu, Julianne DiRosario and Douglas M. McCarty
Mol Ther 13: S191-S191; doi:10.1016/j.ymthe.2006.08.564
495. Transfer of LEDGF to the Mouse Retina Via Systemic AAV Vector Administration
Lyudmyla G. Glushakova, Marina Gorbatuyk, Yuanging Lu, Sihong Song, Min Zheng, Toshimichi Shinohara and William W. Hauswirth
Mol Ther 13: S192-S192; doi:10.1016/j.ymthe.2006.08.565
496. AAV-Mediated, Somatic Gene Transfer to RPE Cells in Order To Study the Pathogenesis of Macular Degeneration: Proteomic and Genomic Analysis
Garrett C. Du Bois, Petya D. Radoeva and Jean Bennett
Mol Ther 13: S192-S192; doi:10.1016/j.ymthe.2006.08.566
497. Central CART Gene Delivery by Recombinant AAV Vector Decreases Lean Body Mass in Diet-Induced Obese Male Rats
Keyun Qing and Yanyun Chen
Mol Ther 13: S192-S193; doi:10.1016/j.ymthe.2006.08.567
498. AAV |[Delta]|264CFTR Enhances Maturation of |[Delta]|F508CFTR and wt CFTR Expression
Liudmila Cebotaru, Terence R. Flotte and William B. Guggino
Mol Ther 13: S193-S193; doi:10.1016/j.ymthe.2006.08.568
499. Improving the Stability of Ad-AAV Hybrid Vectors
Haim Burstein, Richard Peluso, Ziv Sandalon, Kurt Lustig and Tony Stepan
Mol Ther 13: S193-S193; doi:10.1016/j.ymthe.2006.08.569
500. Tetanus Toxin Heavy Chain-Streptoavidin Fusion Protein for Targeted Motor Neuron Gene Delivery through Metabolically Biotinylated AAV
Qingshan Teng, Jeffrey S. Bartlett, Thais Federici, Jun Yang and Nicholas M. Boulis
Mol Ther 13: S193-S193; doi:10.1016/j.ymthe.2006.08.570
501. RheoSwitch|[reg]| Therapeutic System-Inducible Recombinant AAV Vectors for Tightly Regulated Transgene Expression
Dawn Karzenowski, Zhijian J. Chen, David W. Potter and Malla Padidam
Mol Ther 13: S194-S194; doi:10.1016/j.ymthe.2006.08.571
502. Advances in the Application of Combinatorial Technology for the Optimization of Adeno-Associated Virus (AAV) Vectors
Luca Perabo, Jan Endell, Stephan Maersch, Michael Hallek and Hildegard Buening
Mol Ther 13: S194-S194; doi:10.1016/j.ymthe.2006.08.572
503. A Novel Herpes Simplex Virus Helper Based Production of Adeno-Associated Virus Vectors for Treatment of Retinal Angiogenesis
Guo-jie Ye, Chris Drogemuller, Darby Thomas, Marina Scotti, Wen Kang, David Knop, Sanford Boye, Peter Pechan, James Peterson, William Hauswirth, Abraham Scaria and Samuel Wadsworth
Mol Ther 13: S194-S194; doi:10.1016/j.ymthe.2006.08.573
504. Neuronal Affinity of a C7C Loop Peptide Identified through Phage Display
Thais Federici, James K. Liu, Qingshan Teng, Mary Garrity-Moses, Jun Yang and Nicholas M. Boulis
Mol Ther 13: S195-S195; doi:10.1016/j.ymthe.2006.08.574
505. Advances in Large-Scale Production of Recombinant Adeno-Associated Vectors
Alejandro Negrete, Masashi Urabe Urabe and Robert M. Kotin
Mol Ther 13: S195-S195; doi:10.1016/j.ymthe.2006.08.575
506. Production of Recombinant Adeno-Associated Virus Type 1 Vector Using a Herpes Simplex Virus Based System
Wen Kang, Chris Drogemuller, Marina M. Scotti and Guo-jie Ye
Mol Ther 13: S195-S195; doi:10.1016/j.ymthe.2006.08.576
507. Engineering a Novel AAV Variant for Purification Via Immobilized Metal Affinity Chromatography
James T. Koerber, Jae-Hyung Jang Jang, Julie Yu, Ravindra Kane and David V. Schaffer
Mol Ther 13: S196-S196; doi:10.1016/j.ymthe.2006.08.577
508. Development of Optimized AAV2 Vector Biosynthesis and Purification Processes To Support High Capacity Production of Clinical Vectors of High Purity and Potency
Bernd Hauck, Jitin Bajaj, Sonali Joyce, Guang Qu, Olga A. Zelenaia, Katherine A. High and J. Fraser Wright
Mol Ther 13: S196-S196; doi:10.1016/j.ymthe.2006.08.578
509. Adeno-Associated Vector Mediated Delivery of Anti-HIV Genes
Mayur C. Tamhane and Ramesh Akkina
Mol Ther 13: S196-S196; doi:10.1016/j.ymthe.2006.08.579
510. Detection and Quantification of rcAAV in rAAV Stocks by Real-Time qPCR
Traci L. Mayfield, Irina Korytov, Joyce D. Francis, David R. Knop and Richard O. Snyder
Mol Ther 13: S196-S197; doi:10.1016/j.ymthe.2006.08.580
511. An Enzyme Linked Immunosorbent Assay for the Detection of Herpes Simplex Virus Type 1 Proteins in a Novel rAAV Production and Purification Process
Guo-jie Ye and Tammy Mandell
Mol Ther 13: S197-S197; doi:10.1016/j.ymthe.2006.08.581
512. Characterization of Adsorption of Adeno-Associated Virus to Commonly Used Catheter Materials: AAV2 vs. AAV1/2
Daisy P. Cross and Marty Morris
Mol Ther 13: S197-S197; doi:10.1016/j.ymthe.2006.08.582
513. A Simple Method To Ensure Titer Conservation of AAV2 Vector Preparations Delivered with Stainless Steel Needles
Elias T. Ketchum, Kevin Kwok, Anthony Ramirez, Junshan Hao, Brian Kruegel, Dominick Vacante, Raymond Bartus and Mehdi Gasmi
Mol Ther 13: S197-S198; doi:10.1016/j.ymthe.2006.08.583
514. mRNA Transfection Results in Efficient Overexpression of Transgenes in Leukemic Cell Lines and Hematopoietic Stem Cells
Martin F. Ryser, Marcus Gentsch, Fernando Ugarte, Harry L. Malech and Sebastian Brenner
Mol Ther 13: S198-S198; doi:10.1016/j.ymthe.2006.08.585
515. Sequence Requirements for Alveolar Epithelial Cell-Specific Plasmid Nuclear Import
James V. DeGiulio and David A. Dean
Mol Ther 13: S198-S198; doi:10.1016/j.ymthe.2006.08.586
516. Development of a Minicircle Vector Free of Plasmid Bacterial DNA Sequences and Capable of |[oslash]|C31-Mediated Site-Specific Integration
Zhi-Ying Chen, Cheng-Yi He, Anja Ehrhardt, Hui Xu and Mark A. Kay
Mol Ther 13: S198-S199; doi:10.1016/j.ymthe.2006.08.587
517. Lipopolythioureas: Non Cationic System for Gene Delivery
Jeanne Leblond, Nathalie Mignet, Maria-Vittoria Spanedda, Daniel Scherman and Jean Herscovici
Mol Ther 13: S199-S199; doi:10.1016/j.ymthe.2006.08.588
518. Mechanism of Difference in the Transcription Activity of Nucleus-Delivered Transgene Introduced by Adenovirus and Lipoplex
Hidetaka Akita, Susumu Hama, Hiroyuki Mizuguchi and Hideyoshi Harashima
Mol Ther 13: S199-S199; doi:10.1016/j.ymthe.2006.08.589
519. Development of S/MAR Plasmid Vectors for Persistent Expression and Maintenance, In Vivo
Orestis Argyros, Suet-Ping Wong, Andrew A. Miller and Richard Harbottle
Mol Ther 13: S199-S200; doi:10.1016/j.ymthe.2006.08.590
520. ProTIS, a Method for Prediction of Insertion-Site Preferences into Chromosomes of Vectors Used for Gene Therapy
Aron M. Geurts, Christopher S. Hackett, Jason B. Bell, Tracy L. Bergemann, Lara S. Collier, Corey M. Carlson, David A. Largaespada and Perry B. Hackett
Mol Ther 13: S200-S200; doi:10.1016/j.ymthe.2006.08.591
521. Gene Transfer of an Anti-CCR5 siRNA by Sleeping Beauty (SB) Transposon System
Mayur C. Tamhane and Ramesh Akkina
Mol Ther 13: S200-S200; doi:10.1016/j.ymthe.2006.08.592
522. Neural Retina Limits Delivery Non Viral Vectors to Retinal Pigment Epithelium
Liesbeth Peeters, Niek Sanders, Koen Boussery, Johan Van de Voorde, Joseph Demeester and Stefaan De Smedt
Mol Ther 13: S200-S201; doi:10.1016/j.ymthe.2006.08.593
523. Deoxyribonuclease I and Endonuclease G Are Host Defense Enzymes Responsible for Inactivation of Foreign DNA in Kidney Tubular Epithelial Cells
Timea Buzder, Xiaoyan Yin, Xiaoying Wang, Gaspar Banfalvi and Alexei G. Basnakian
Mol Ther 13: S201-S201; doi:10.1016/j.ymthe.2006.08.594
524. Analysis of Unique Proteins Bound to Sequentially Injected DOTAP:DNA Vectors
Christine C. Conwell and Leaf Huang
Mol Ther 13: S201-S201; doi:10.1016/j.ymthe.2006.08.595
525. Mutants of phiC31 Integrase with Increased Efficiency and Specificity
Annahita Keravala, Solomon Lee, Eric C. Olivares, Bhaskar Thyagarajan, Alfonso Farruggio, Vanessa E. Gabrovsky and Michele P. Calos
Mol Ther 13: S201-S202; doi:10.1016/j.ymthe.2006.08.596
526. Induction of Apoptosis in Melanoma Cell Lines by the Noxa Gene
Mohamed Hassan, Amine Alaoui, Alireza Mirmohammadsadegh, Alessandra Marini, Sandeep Nambiar and Ulrich R. Hengge
Mol Ther 13: S202-S202; doi:10.1016/j.ymthe.2006.08.597
527. Pharmaceutical Plasmid Manufacturing: Development of Economical and Innovative Process Solutions
Joachim Schorr, Markus Mueller, Juergen Hubbuch and Andreas Frerix
Mol Ther 13: S202-S202; doi:10.1016/j.ymthe.2006.08.598
528. Significant Silencing Effect of a Multifunctional Envelope-Type Nano Device Encapsulating Antisense Oligodeoxynucleotide and Double-Stranded siRNA
Kentaro Kogure, Yoshio Nakamura, Ikramy A. Khalil, Shiroh Futaki and Hideyoshi Harashima
Mol Ther 13: S202-S203; doi:10.1016/j.ymthe.2006.08.599
529. Development of Novel Systemic Gene Delivery System for Cancer Therapy with Tumor-Specifically Cleavable PEG-Lipid
Hiroto Hatakeyama, Hidetaka Akita, Kentaro Kogure, Motoi Oishi, Yukio Nagasaki, Hideo Kobayashi, Hiroshi Kikuchi and Hideyoshi Harashima
Mol Ther 13: S203-S203; doi:10.1016/j.ymthe.2006.08.600
530. The Effects DNA Molecular Weights and Conformations on Cell Uptake and the Binding Interaction with Cationic Polymers Used for Non-Viral Gene Delivery
Charlie Y.-M. Hsu, Cezary Kucharski and Hasan Uludag
Mol Ther 13: S203-S204; doi:10.1016/j.ymthe.2006.08.601
531. Complexes of DNA-Cationic Liposomes with Baculovirus GP64 Envelope Fusion Protein Vesicles Demonstrate Enhanced Transfection Efficiency
Ghiabe H. Guibinga, Shaochun Song, Jeanne Loring and Theodore Friedmann
Mol Ther 13: S204-S204; doi:10.1016/j.ymthe.2006.08.602
532. An Inducible Fed-Batch Fermentation Process for Scale-Up and Production of DNA Vaccines and Gene Medicines
Aaron E. Carnes, James A. Williams and Clague P. Hodgson
Mol Ther 13: S204-S204; doi:10.1016/j.ymthe.2006.08.603
533. Recombinant (KHG)6-FGF2 Biopolymer for Targeted Gene Transfer
Arash Hatefi and Hamid Ghandehari
Mol Ther 13: S204-S205; doi:10.1016/j.ymthe.2006.08.604
534. Silk-Elastinlike Polymers for Matrix-Mediated Adenoviral Gene Delivery
Arash Hatefi and Hamid Ghandehari
Mol Ther 13: S205-S205; doi:10.1016/j.ymthe.2006.08.605
535. Physicochemical and Transfection Properties of Cationic Hydroxyethylcellulose/DNA Nanoparticles
Farzaneh Fayazpour, Bart Lucas, Carmen Alvarez-Lorenzo, Niek Sanders, Joseph Demeester and Stefaan De Smedt
Mol Ther 13: S206-S206; doi:10.1016/j.ymthe.2006.08.606
536. Charge Switchable Helper Lipids for Gene Delivery
Mark W. Grinstaff, Carla A. Hernandez Prata, Yougen Li, Dan Luo and Tom J. MacIntosh
Mol Ther 13: S206-S206; doi:10.1016/j.ymthe.2006.08.607
537. Charge-Reversal Lipids for Gene Transfection
Mark W. Grinstaff, Carla A. Hernandez Prata, Steven R. Meyers, Philippe Barthelemy, Yougen Li, Dan Luo, Tom J. McIntosh and Stephen J. Lee
Mol Ther 13: S206-S207; doi:10.1016/j.ymthe.2006.08.608
538. DNAvaletTM Transfection Reagent
Carla Prata
Mol Ther 13: S207-S207; doi:10.1016/j.ymthe.2006.08.609
539. Unraveling the Mechanisms Underlying Silencing/Activation of Episomal Vectors In Vivo
Efren Riu, Zhi-Ying Chen and Mark A. Kay
Mol Ther 13: S207-S207; doi:10.1016/j.ymthe.2006.08.610
540. Genetic Intervention towards Improving the Long Term Outcome of CABG Using a Lipid Peptide DNA Vector System
Scott A. Irvine, Faiza Afzal, Qing H. Meng, Jimmy Ho, Andrew Wu, Jean R. McEwan and Stephen L. Hart
Mol Ther 13: S207-S208; doi:10.1016/j.ymthe.2006.08.611
541. Species-Specific Characteristics in Muscle Resistance and Their Impact on In Vivo Electroporation
Amir S. Khan, Patricia A. Brown, Melissa A. Pope and Ruxandra Draghia-Akli
Mol Ther 13: S208-S208; doi:10.1016/j.ymthe.2006.08.613
542. Development and Characterization of Ultrasound Responsive Microbubbles for Gene Delivery
Ine Lentacker, Stefaan C. De Smedt, Joseph Demeester and Niek N. Sanders
Mol Ther 13: S208-S209; doi:10.1016/j.ymthe.2006.08.614
543. Monitoring Transgene Expression by Radio-Peptide Positron Emission Tomography
Amiq Gazdhar, Murat Bilici, Erick Ayuni, Thomas Krause, Michal Hofmann and Raplh A. Schmid
Mol Ther 13: S209-S209; doi:10.1016/j.ymthe.2006.08.615
544. PLGA Nanoparticles for DNA Vaccination |[ndash]| Waiving Complexity and Increasing Efficiency
Jacob Gvili and Marcelle Machluf
Mol Ther 13: S209-S209; doi:10.1016/j.ymthe.2006.08.616
545. Comparison between Different Tissues for Efficient and Safe DNA Electrotransfer In Vivo
Franck M. Andre and Lluis M. Mir
Mol Ther 13: S210-S210; doi:10.1016/j.ymthe.2006.08.617
546. Targeted Non-Viral Gene Delivery Using Microbubbles and Focused Ultrasound
Ahad Rahim, Sarah L. Taylor, Nigel L. Bush, Gail R. ter Haar, Jeff C. Bamber and Colin D. Porter
Mol Ther 13: S210-S210; doi:10.1016/j.ymthe.2006.08.618
547. Magnetically Driven Non-Viral Gene Delivery Efficiently Transfects Cultured Smooth Muscle Cells and Inhibits Their Growth Via Adiponectin Transgene Expression
Boris Polyak, Michael Chorny, Ivan Alferiev, Kenneth Walsh, Gary Friedman and Robert J. Levy
Mol Ther 13: S211-S211; doi:10.1016/j.ymthe.2006.08.619
548. Cellular Defense Response in Transduced and Transfected Human Tumor and Primary Cell Lines
Riikka Pellinen, Outi Rautsi, Saara Lehmusvaara, Sillanp|[auml]||[auml]| Maarit, Hakkarainen Tanja, V|[auml]|h|[auml]|kangas Elisa, Yl|[auml]|-herttuala Seppo, Hinkkanen Ari, Julkunen Ilkka and Wahlfors Jarmo
Mol Ther 13: S211-S211; doi:10.1016/j.ymthe.2006.08.620
549. Ultrasound with Microbubbles Enhances Gene Expression of Plasmid DNA Delivered through Portal Vein Injection
Zhenping Shen, Andrew A. Brayman, Liping Chen and Carol H. Miao
Mol Ther 13: S212-S212; doi:10.1016/j.ymthe.2006.08.621
550. Delivery of Oligodeoxynucleotides into Human Saphenous Veins and the Adjunct Effect of Ultrasound and Microbubbles
Tetsuya Kodama, Peng H. Tan, Andrew J.T. George and Martin J.K. Blomley
Mol Ther 13: S212-S212; doi:10.1016/j.ymthe.2006.08.622
551. The Use of Electroporation To Transfer Plasmids to the Lung Results in Reduced TLR9 Signaling and Inflammation
Rui Zhou, James E. Norton, Ning Zhang and David A. Dean
Mol Ther 13: S212-S213; doi:10.1016/j.ymthe.2006.08.623
552. Collateral Circulation under Cerebral Ischemia by Hypoxia Inducible Factor Naked DNA in Rat Indirect-Bypass Model
Mitsuhiro Anan, Tatsuya Abe, Takeshi Matsuda, Ryo Inoue, Keisuke Ishii, Minoru Fujiki and Hidenori Kobayashi
Mol Ther 13: S213-S213; doi:10.1016/j.ymthe.2006.08.624
553. Development of Echo-Contrast Gas Entrapping Liposome as Gene and siRNA Delivery Tool
Yoichi Negishi, Tetsuya Fukuyama, Yoko Endo, Ryo Suzuki, Kumiko Tanaka, Kaori Sawamura, Tomoko Takizawa, Kazuo Maruyama and Yukihiko Aramaki
Mol Ther 13: S213-S213; doi:10.1016/j.ymthe.2006.08.625
554. Improved Efficiency of Gene Expression Using the Stiletto|[trade]| Endocardial Direct Injection Catheter
Samuel J. Epstein, Wendy Naimark, Maria Palasis, Kian K. Poh, Tengiz Tkebuchava, Corinne Luedemann and Douglas Losordo
Mol Ther 13: S213-S214; doi:10.1016/j.ymthe.2006.08.626
555. Large-Scale, Flow-Based Electroporation To Deliver Engineered Zinc Finger Protein Nucleases That Mediate High-Efficiency Disruption of the Human CCR5 Gene
Michael C. Holmes, Linda Liu, Elena Perez, Linhong Li, Rama Shivakumar, Cornell Allen, Olga Liu, Jeffrey C. Miller, Fyodor D. Urnov, Kenneth Kim, Edward J. Rebar, Dale Ando, Philip D. Gregory, James Riley, Madhusudan Peshwa and Carl June
Mol Ther 13: S214-S214; doi:10.1016/j.ymthe.2006.08.627
556. Proteasome Inhibitors Increase Cationic-Lipid Mediated Gene Transfer in A549 Cells In Vitro
Uta Griesenbach, Maresa Brake, Aaron Gardner and Eric W.F.W. Alton
Mol Ther 13: S214-S214; doi:10.1016/j.ymthe.2006.08.628
557. A Study of AAV2/1/SERCA2a Delivered Via the V-Focus Cardiac Delivery System in an Ovine Pacing Model of Heart Failure
Melissa J. Byrne, David Kaye and John M. Power
Mol Ther 13: S214-S215; doi:10.1016/j.ymthe.2006.08.629
558. High Efficiency Transfection of Primary Cells for Basic Research and Gene Therapy
Hans-Guenter Bruenker
Mol Ther 13: S215-S215; doi:10.1016/j.ymthe.2006.08.630
559. A Pseudo-Exon Derived from an Intronic Insertion is Responsible for Duchenne-Like Muscular Dystrophy in the Welsh Corgi Dog
Bruce F. Smith and Joseph N. Kornegay
Mol Ther 13: S215-S215; doi:10.1016/j.ymthe.2006.08.632
560. GNE Gene Replacement in Hereditary Inclusion Body Myopathy
Phillip B. Maples, Daniel Darvish, Gregory Nemunaitis, Esther Chang, Julie Ogden and John Nemunaitis
Mol Ther 13: S215-S216; doi:10.1016/j.ymthe.2006.08.633
Abstracts
561. Novel Tissue-Specific Regulatory Cassettes Direct High-Level Transgene Expression in Skeletal and Cardiac Muscle
Maja Z. Salva, Charis L. Himeda, Phillip Tai, Eiko Nishiuchi, Eric E. Finn, James M. Allen, Paul Gregorevic, Michael J. Blankinship, Leonard A. Meuse, Jeffrey S. Chamberlain and Stephen D. Hauschka
Mol Ther 13: S216-S216; doi:10.1016/j.ymthe.2006.08.634
562. Ex Vivo Gene Therapy for Duchenne Muscular Dystrophy: Lentiviral Vectors, Exon Skipping and PhiC31 Integrase Approaches
Simon P. Quenneville, Pierre Chapdelaine, Joel Rousseau and Jacques P. Tremblay
Mol Ther 13: S216-S216; doi:10.1016/j.ymthe.2006.08.635
563. Correction of Glycogen Storage Disease Type II by Systemic Delivery of an AAV2/8 Vector Containing a Muscle-Specific Promoter
Baodong Sun, Ping Li, Brown Talmage, Bird Andrew, Zhen Yan and Dwight D. Koeberl
Mol Ther 13: S217-S217; doi:10.1016/j.ymthe.2006.08.636
564. Correction of Hyposialylation in Hereditary Inclusion Body Myopathy, by Ex-Vivo Therapy
Zo|[eacute]| Coulombe, Dominic Gagn|[eacute]| and Jacques P. Tremblay
Mol Ther 13: S217-S217; doi:10.1016/j.ymthe.2006.08.637
565. Acceleration of Fracture Healing with Adenovirally Transduced Human BMP-2 and -6 Genes in Horse Metatarsal Osteotomy and Ostectomy Models
Akikazu Ishihara, Alicia L. Bertone, Alan L. Litsky, John S. Mattoon and Stephen E. Weisbrode
Mol Ther 13: S217-S218; doi:10.1016/j.ymthe.2006.08.638
566. Delaying the Onset of Diabetes in the NOD Mouse Using Exosomes Derived from Dendritic Cells Transfected with Adenoviral Vectors
Melanie A. Ruffner, Seon Hee Kim, Nicole R. Bianco, William J. Shufesky, Nick Giannoukakis, Adrian E. Morelli and Paul D. Robbins
Mol Ther 13: S218-S218; doi:10.1016/j.ymthe.2006.08.639
567. Adeno-Associated Virus Vector 8 (AAV8) Provides Efficient Gene Delivery to Skeletal Muscles In Utero by Systemic Adminstration
Bhanu Munil Koppanati, Juan Li, Bing Wang, Xiao Xiao and Paula Ruth Clemens
Mol Ther 13: S218-S218; doi:10.1016/j.ymthe.2006.08.640
568. Ex Vivo Mesenchymal Stem Cell Therapy with rAAV2 Encoding BMP-2 Enhances Bone Regeneration in Ovariectomized Mouse Model
Sanjay Kumar, Tim R. Nagy and Selvarangan Ponnazhagan
Mol Ther 13: S219-S219; doi:10.1016/j.ymthe.2006.08.641
569. Gene Therapy of Uterine Leiomyoma: Adenovirus-Mediated Herpes Simplex Virus Thymidine Kinase/Ganciclovir Treatment Inhibits Growth of Human and Rat Leiomyoma Cells In Vitro and in a Nude Mouse Model
Salama A. Salama, Marwa W. Kamel, Gregory M. Christman, Hui Q. Wang and Ayman A. Al-Hendy
Mol Ther 13: S219-S219; doi:10.1016/j.ymthe.2006.08.642
570. Ectopic Expression of Adenoviral Smad7 Significantly Reduces Hypertrophic Scarring in Rabbit Ears by Abrogating TGF|[beta]|1 Signalling
Juergen Kopp, Harun Seyhan, Katrin Messingschlager, Vanessa Pe|[ntilde]|a de Bender and Raymund E. Horch
Mol Ther 13: S219-S220; doi:10.1016/j.ymthe.2006.08.643
571. Increasing BMP Responsiveness in Human Mesenchymal Stem Cells In-Vitro by Delivery of the Osteoinductive LMP-1 Gene
Manjula Viggeswarapu, Maggie Bargouti, Mesfin Teklemariam, Chantrice Rogers, Liping Zhu, Nancy Baker, Louisa F. Titus and Scott D. Boden
Mol Ther 13: S220-S220; doi:10.1016/j.ymthe.2006.08.644
572. rAd-p21 To Reduce Excessive Dermal Scarring: Efficacy, Expression, and Tensile Strength in Animal Models
David W. Kang, Dan-Ling Gu, L. David Looper, Barry J. Sugarman, Erlinda M. Quijano and Monica L. Zepeda
Mol Ther 13: S220-S220; doi:10.1016/j.ymthe.2006.08.645
573. Enhanced Level of Gene Correction Mediated by Oligonucleotides Containing CpG Modification in the mdx Mouse Model for Duchenne Muscular Dystrophy
Carmen Bertoni, Arjun Rustagi and Thomas A. Rando
Mol Ther 13: S221-S221; doi:10.1016/j.ymthe.2006.08.646
574. Models of Cancer Cachexia: Treatment with Inhibition of NF-kB
Jad R. Maamary, Zhilong Jiang and Paula R. Clemens
Mol Ther 13: S221-S221; doi:10.1016/j.ymthe.2006.08.647
575. Correction of Ventilation in Glycogen Storage Disease Type II Mice after Gel-Mediated Delivery of Adeno-Associated Virus Serotype 1 Vectors
Cathryn Mah, Lara R. DeRuisseau, Christina A. Pacak, Melissa A. Lewis, David D. Fuller and Barry J. Byrne
Mol Ther 13: S221-S222; doi:10.1016/j.ymthe.2006.08.648
576. Hypoxic Adipocytes Support Early Heterotopic Bone Formation
Elizabeth A. Olmsted-Davis, Francis H. Gannon, Zbigniew Gugala, John A. Hipp, Christine Foultier-Dilling, Michael H. Heggeness and Alan R. Davis
Mol Ther 13: S222-S222; doi:10.1016/j.ymthe.2006.08.649
577. Inducible Regulation of Runx2-Stimulated Osteogenesis
Charles A. Gersbach, Joseph M. Le Doux, Robert E. Guldberg and Andres J. Garcia
Mol Ther 13: S222-S223; doi:10.1016/j.ymthe.2006.08.650
578. Suppression of Inflammation Following Intramuscular Administration of Pseudotyped AAV-TNFR:Fc Vectors in a Rat Model of Arthritis
Haim Burstein, Kurt Lustig and Ziv Sandalon
Mol Ther 13: S223-S223; doi:10.1016/j.ymthe.2006.08.651
579. Non-Invasive Measurement of Maximal Strength in the Normal and Dystrophic Dog Quadriceps Using Magnetic Stimulation of the Femoral Nerve
Frederick J. Balzer, Martin K. Childers, Janet R. Bogan, Daniel J. Bogan, Joe N. Kornegay and Hansell H. Stedman
Mol Ther 13: S223-S223; doi:10.1016/j.ymthe.2006.08.652
580. Gene Therapy of Chronic Hepatitis B Infection Using a High-Capacity Adenovirus Expressing Interleukin 12 under the Control of a Liver Specific Mifepristone-Inducible Promoter
Julien S. Crettaz, Pedro Berraondo, Laura Ochoa, Astrid Paneda, Itziar Otano, Cristina Olague, Africa Vales, Stefan Kochanek, Jesus Prieto and Gloria Gonzalez-Aseguinolaza
Mol Ther 13: S224-S224; doi:10.1016/j.ymthe.2006.08.654
581. IL-23 Is Required for B-Cell Memory after CD40 Ligand-Modified Dendritic Cell Vaccination
Mingquan Zheng, Jolia A. Bindas, Rekha Rapaka and Jay K. Kolls
Mol Ther 13: S224-S224; doi:10.1016/j.ymthe.2006.08.655
582. CNS Gene Delivery Targeting CCR3 Protects Brain Microglia from HIV-1
Lokesh Agrawal and David S. Strayer
Mol Ther 13: S224-S225; doi:10.1016/j.ymthe.2006.08.656
583. Evaluation of a pDNA-Based Anthrax Vaccine and Immune Correlates of Protection in Mice and Non-Human Primates
Peggy Lalor, Vanessa Whitlow, C. Richard Lyons, Julie Lovechik, Mark R. Perry, Jane Morrow, Peter Hobart, Holly Horton, Larry Smith, David Kaslow and Alain Rolland
Mol Ther 13: S225-S225; doi:10.1016/j.ymthe.2006.08.657
584. Enhanced Inhibition of HIV Using Combinatorial Genetic Therapy Against HIV-1 Integrase Delivered by SV40 Vectors
Elena I. Marusich and David S. Strayer
Mol Ther 13: S225-S225; doi:10.1016/j.ymthe.2006.08.658
585. Improved Efficacy of DNA Vaccines for HIV and Smallpox Using Constant-Current Electroporation
Lauren Hirao, Amir S. Khan, Ruxandra Draghia-Akli and David B. Weiner
Mol Ther 13: S226-S226; doi:10.1016/j.ymthe.2006.08.659
586. Anti-HIV-1 Neutralizing Antibody Gene Delivery to Rhesus Macaques and Rodents: A Novel Vaccination Approach
K. Reed Clark, Jianchao Zhang, David C. Montefiori and Philip R. Johnson5
Mol Ther 13: S226-S226; doi:10.1016/j.ymthe.2006.08.660
587. HIV-1 Glycoprotein gp120 Induces Apoptosis in the Caudate-Putamen In Vivo: Implications for Gene Transfer of Anti-Oxidant Enzymes Using SV40 Vectors
Jean-Pierre Louboutin, Lokesh Agrawal, Beverly A.S. Reyes, Elisabeth J. van Bockstaele and David S. Strayer
Mol Ther 13: S226-S227; doi:10.1016/j.ymthe.2006.08.661
588. Hepatic HB-EGF (Heparin-Binding EGF-Like Growth Factor) Gene Therapy for Fulminant Hepatic Failure in Mice: More Potent Protective and Mitogenic Effects for Hepatocytes Than HGF (Hepatocyte Growth Factor)
Ken-ichiro Kosai, Ngin Cin Khai and Tomoyuki Takahashi
Mol Ther 13: S227-S227; doi:10.1016/j.ymthe.2006.08.662
589. Repeated Recombinant Adenovirus (rAd) Administration To Generate Mucosal Antibodies (Abs) vs Botulinum Toxin A (BoNT/A)
Marlene S. Strayer, Andrew B. Maksymowych, Carmen N. Nichols, Steven Elek, Jean-Pierre Louboutin, Lance L. Simpson and David S. Strayer
Mol Ther 13: S227-S228; doi:10.1016/j.ymthe.2006.08.663
590. Recombinant Adenovirus Vaccines Against Anthrax
Michael J. McConnell and Michael J. Imperiale
Mol Ther 13: S228-S228; doi:10.1016/j.ymthe.2006.08.664
591. Development of Anti-JC Virus |[ldquo]|Designer T Cells|[rdquo]| for Progressive Multifocal Leukoencephalopathy (PML) Immunotherapy
Wen Yang, Esther Beaudoin, Renaud A. Du Pasquier, Igor J. Koralnik and Richard P. Junghans
Mol Ther 13: S228-S229; doi:10.1016/j.ymthe.2006.08.665
592. Effective Transduction of Nondividing PBL, Monocytes and Monocyte-Derived Macrophages with SV40-Derived Vectors Protects from HIV-1 Challenge
Elena I. Marusich and David S. Strayer
Mol Ther 13: S229-S229; doi:10.1016/j.ymthe.2006.08.666
593. Combination Anti-HIV-1 Gene Therapy Simultaneously Targeting CCR5 and Rev Protein Using SV40-Derived Vectors Inhibits Replication of HIV
Alena A. Chekmasova and David S. Strayer
Mol Ther 13: S229-S229; doi:10.1016/j.ymthe.2006.08.667
594. Protection Against In Vivo Tumor Growth after Electroporation-Enhanced DNA Vaccination with the Hepatitis C Virus Non-Structural 3/4A
Rune Kjeken, Gustaf Ahlen, Jonas Soderholm, Torunn Tjelle, Iacob Mathiesen and Matti Sallberg
Mol Ther 13: S229-S230; doi:10.1016/j.ymthe.2006.08.668
595. Nasal Delivery of Adenovirus Expressing the Ebola Glycoprotein Protects Mice Against Ebola Virus in the Presence of Preexisting Immunity to the Vaccine Carrier
Maria Croyle, Heinz Feldmann, Steven Jones, James M. Wilson and Gary P. Kobinger
Mol Ther 13: S230-S230; doi:10.1016/j.ymthe.2006.08.669
596. A Novel Replication Incompetent Human Subgroup D Adenoviral Vector Based on Type 49: Manufacture on PER.C6|[reg]|, Cell Tropism and Immunogenicity
Angelique Lemckert, Jos Grimbergen, Anna Thorner, Ronald Vogels, Paul Quax, Jaap Goudsmit, Dan Barouch and Menzo Havenga
Mol Ther 13: S230-S230; doi:10.1016/j.ymthe.2006.08.670
597. DNA Vaccines: Induction of Humoral and Cellular Responses Via Skin or Muscle Immunization Enhanced by Electroporation
Lei Zhang, Georg Widera, Susan Bleecher and Dietmar Rabussay
Mol Ther 13: S231-S231; doi:10.1016/j.ymthe.2006.08.671
598. Effective Humoral and Cellular Smallpox-Immune Responses Using a Combination of Plasmids Delivered by Intramuscular Injection Followed by Constant-Current Electroporation in Rabbits
Amir S. Khan, Lauren Hirao, David B. Weiner and Ruxandra Draghia-Akli
Mol Ther 13: S231-S231; doi:10.1016/j.ymthe.2006.08.672
599. Neuron Loss Mediated by HIV-1 gp120 In Vivo: Neuroprotection Using SV40 Gene Transfer of Antioxidant Enzymes
Jean-Pierre Louboutin, Lokesh Agrawal, Beverly A.S. Reyes, Elisabeth J. van Bockstaele and David S. Strayer
Mol Ther 13: S232-S232; doi:10.1016/j.ymthe.2006.08.673
600. Transduced Cells with Lentiviral Vector Expressing gp41-Derived c-Peptide Are Protected from HIV-1 Infection
Kwang-soo Ahn, Seok Kee Chang, Dokeun Kim, Won Shin and Yeowon Sohn
Mol Ther 13: S232-S232; doi:10.1016/j.ymthe.2006.08.674
601. Potential of Gene Transfer for HIV/AIDS Therapy: Overwhelming and Repeated HIV Challenge Selects for Transduced Lymphocytes Capable of Long-Term Survival and Enduring Resistance to HIV
Elena I. Marusich and David S. Strayer
Mol Ther 13: S232-S233; doi:10.1016/j.ymthe.2006.08.675
602. Effectiveness of Gene Delivery Targeting HIV-1 Integrase in Inhibiting HIV Integration: Lack of HIV-1 Genomes in T-Lymphocytes during Repeated Challenges with HIV-1
Elena I. Marusich, Christine B. Mitchell and David S. Strayer
Mol Ther 13: S233-S233; doi:10.1016/j.ymthe.2006.08.676
604. Comparative Analysis of Different Methods for Quantitative Evaluation of Neutralizing Antibody to Ebola Virus in a Biosafety Level 2 or 4 Environment
Hideki Ebihara, Xiangguo Qiu, Steven Theriault, Matthew Klassen, Ute Stroeher, Jim Strong, Steven Jones, James M. Wilson, Heinz Feldmann and Gary Kobinger
Mol Ther 13: S233-S234; doi:10.1016/j.ymthe.2006.08.678
605. Long-Term Protection Afforded by a Single Administration of an Ad-Based Anti-Y. pestis Vaccine Against a Lethal Respiratory Challenge with Y. pestis
Maria J. Chiuchiolo, Anja Krause, Ronald G. Crystal and Julie L. Boyer
Mol Ther 13: S234-S234; doi:10.1016/j.ymthe.2006.08.679
606. Identification of a 45-aa Domain of the F12-Vif Mutant Possessing Anti-HIV Activity
Simona Porcellini, Rossella Lupo, Giuliana Vallanti, Maurizio Federico, Fulvio Mavilio and Chiara Bovolenta
Mol Ther 13: S234-S234; doi:10.1016/j.ymthe.2006.08.680
607. Novel Adeno-Associated Viruses as Vaccine Carriers for HIV-1: Evaluation in Non-Human Primates
Roberto Calcedo, Yan Zhi, Joanita M. Figueredo, Judith I. Franco, Julie C. Johnston, Rebecca L. Grant and James M. Wilson
Mol Ther 13: S234-S235; doi:10.1016/j.ymthe.2006.08.681
608. Dose Escalation of Recombinant Adenovirus-Based Influenza Virus Vaccine Encoding the Full Length Hemagglutinin (HA) of the A/Vietnam/1203/2004 (H5N1) To Immunize Na|[iuml]|ve and Ad-Immune Mice
Julia Steitz, Wentao Gao, Edward Nwanegbo, Ruben O. Donis, Jacqueline M. Katz and Andrea Gambotto
Mol Ther 13: S235-S235; doi:10.1016/j.ymthe.2006.08.682
609. Acute-Phase Toxicity Following Systemic Administration of Non-Human Primate Derived Adenoviral Vectors to Mice
Suryanarayan Somanthan, Zhe Zhang, Guang-Ping Gao, Martin W. Lock, Peter L. Bell, Soumitra Roy, Arbansjit K. Sandhi and James M. Wilson
Mol Ther 13: S235-S235; doi:10.1016/j.ymthe.2006.08.683
610. The Effect of In Vitro Antiviral Therapy on Lentiviral Transduction
Priscilla Yam, Paola Marcovecchio, Shirley Li, Jiing-Kuan Yee and John A. Zaia
Mol Ther 13: S235-S236; doi:10.1016/j.ymthe.2006.08.684
611. Induction of Persistent Passive Immunity Against Anthrax Toxin by an Adeno-Associated Virus Type rh10 Vector Expressing Anti-Protective Antigen Antibody
Bishnu P. De, Neil R. Hackett, Jian Ping Qiu, Julie L. Boyer, James M. Wilson and Ronald G. Crystal
Mol Ther 13: S236-S236; doi:10.1016/j.ymthe.2006.08.685
613. Challenging an Old Drug in a New Context: Low-Dose Cyclophosphamide in Immunogenetherapy of Cancer
Sebastian Tuve, Shaoheng Ni and Andre Lieber
Mol Ther 13: S236-S237; doi:10.1016/j.ymthe.2006.08.688
614. The Role of the Activated MAPK Pathway through the Oncogenic BRAFV600E-Mutation in the Immune Escaping Mechanism of Melanoma
Hidetoshi Sumimoto and Yutaka Kawakami
Mol Ther 13: S237-S237; doi:10.1016/j.ymthe.2006.08.689
615. Anti-Tumor Activities of IL-12 and IL-23 Are Mediated by Similar, yet Divergent, Effector Mechanisms
JaNean C. Ceidro, Euan Lockhart, Seon-Hee Kim and Paul D. Robbins
Mol Ther 13: S237-S237; doi:10.1016/j.ymthe.2006.08.690
616. Enhancement of Antitumor Activity of Interferons by RNAi-Mediated Silencing of SOCS Genes in Tumor Cells
Yuki Takahashi, Haruka Kaneda, Makiya Nishikawa and Yoshinobu Takakura
Mol Ther 13: S237-S238; doi:10.1016/j.ymthe.2006.08.691
617. Tumor Lysates Prepared from Cells Infected with a Fusogenic Oncolytic HSV Stimulates Potent Antitumor Immunity Against Primary and Metastatic Murine Mammary Carcinoma
Xinping Fu, Lihua Tao and Xiaoliu Zhang
Mol Ther 13: S238-S238; doi:10.1016/j.ymthe.2006.08.692
618. Hydrodynamic Limb Vein-Delivered Xenogeneic Plasmid DNA Cancer Vaccine Effectively Induces Antitumor Protection
Zane C. Neal, Mary Kay Bates and Hans Herweijer
Mol Ther 13: S238-S238; doi:10.1016/j.ymthe.2006.08.693
619. Tumor-Derived Chemokine MCP-1/CCL2 Is Sufficient for Mediating Tumor Tropism of Adoptively Transferred T-Cells
Christine E. Brown, Reena Vishwanath, Brenda Aguilar, WenChung Chang and Michael C. Jensen
Mol Ther 13: S239-S239; doi:10.1016/j.ymthe.2006.08.694
620. Liposome-Based Therapeutic Vaccine for Cervical Cancer
Weihsu Claire Chen and Leaf Huang
Mol Ther 13: S239-S239; doi:10.1016/j.ymthe.2006.08.695
621. Immunological Memory in a Syngeneic Model of Recurrent and Multifocal Glioblastoma
Gwendalyn D. King, James F. Curtin, Chunyan Liu, Catherine Bresee, Sarah B. Honig, Jeffery M. Zirger, Nico VanRooijen, Antoni Ribas, Robert Pechnick, Pedro R. Lowenstein and Maria G. Castro
Mol Ther 13: S239-S239; doi:10.1016/j.ymthe.2006.08.696
622. Effective Prevention of Spontaneous Lung Metastasis of AT6.3 Prostate Cancer by Intravenous Administration of Dendritic Cells Activated by Non-Transmissible Sendai Virus
Tomonori Kato, Yasuji Ueda, Yasuo Yoneyama, Akinao Matsunaga, Megumi Akizawa, Akira Komiya, Hiroyoshi Suzuki, Makoto Inoue, Mamoru Hasegawa, Tomohiko Ichikawa and Yoshikazu Yonemitsu
Mol Ther 13: S240-S240; doi:10.1016/j.ymthe.2006.08.697
623. Polymer Microparticles Delivering a Idiotype/Chemokine Fusion DNA Vaccine Generate Protective Immunity in a Mice Model of B Cell Lymphoma
Sudhir P. Kasturi, Bilal Ghosn, Kassandra S. Thomson, Hong Qin, Larry Kwak and Krishnendu Roy
Mol Ther 13: S240-S240; doi:10.1016/j.ymthe.2006.08.698
624. Conditionally Replicative Adenovirus Vector Overexpressing the ADP (E3-11.6K) Protein and Armed with Human Interferon Alpha
Elena V. Shashkova, Jacqueline F. Spencer, William S.M. Wold and Konstantin Doronin
Mol Ther 13: S240-S241; doi:10.1016/j.ymthe.2006.08.699
625. Viral Shedding after Intratumoral Injection of Adenoviral Vectors to Patients with Cancer
Gloria Gonz|[aacute]|lez-Aseguinolaza, Maria Ruiz, Cristina Olag|[uuml]|e, Jesus Prieto, Juan Ruiz and Bruno Sangro
Mol Ther 13: S241-S241; doi:10.1016/j.ymthe.2006.08.700
626. Inactivated Sendai Virus Particle (HVJ-E) Solely Induces Specific Anti-Tumor Immune Response and Eradicates Murine Carcinoma
Masayuki Kurooka and Yasufumi Kaneda
Mol Ther 13: S241-S241; doi:10.1016/j.ymthe.2006.08.701
627. Calcium Phopspate Precipitation of Adenovirus Enhances Gene Delivery into Human Dendritic Cells
Michael P. Seiler, Stephen M. Gottschalk, Vincenzo Cerullo, Christian Clarke, Cliona M. Rooney and Brendan Lee
Mol Ther 13: S242-S242; doi:10.1016/j.ymthe.2006.08.702
628. Cancer Immunotherapy Against Murine Squamous Cell Carcinoma with Dendritic Cells Activated by Sendai Virus
Akinao Matsunaga, Yasuji Ueda, Yasuo Yoneyama, Yasunori Akutsu, Hideaki Shimada, Tomonori Kato, Shinji Okano, Satoko Shibata, Mamoru Hasegawa, Yoshikazu Yonemitsu, Katsuo Sueishi and Takenori Ochiai
Mol Ther 13: S242-S242; doi:10.1016/j.ymthe.2006.08.703
629. Development and Characterization of Immunotherapy Using SeV/dF-Activated Dendritic Cells Against Squamous Cell Carcinoma
Yasuo Yoneyama, Yasuji Ueda, Akinao Matsunaga, Yasunori Akutsu, Hideaki Shimada, Tomonori Kato, Shinji Okano, Satoko Shibata, Mamoru Hasegawa, Yoshikazu Yonemitsu, Katsuo Sueishi and Takenori Ochiai
Mol Ther 13: S242-S243; doi:10.1016/j.ymthe.2006.08.704
630. A Phase 2 Randomized Study of GM-CSF Gene-Modified Autologous Tumor Cell Immunotherapy (CG8123) with and without Low- Dose Cyclophosphamide in Advanced Stage Non- Small Cell Lung Cancer (NSCLC)
John Nemunaitis, J. Schiller, Helen Ross, David Jablons, H. Harper, D. Sterman, K. Kelly, D. Carbone, A. Lin, D. Maslyar10 and Kristen Hege10
Mol Ther 13: S243-S243; doi:10.1016/j.ymthe.2006.08.705
631. Phase 1/2 Trial of Autologous Tumor Mixed with an Allogeneic GVAX|[reg]| Immunotherapy in Advanced Stage Non-Small Cell Lung Cancer
John Nemunaitis, Thierry Jahan, Helen Ross, Daniel Sterman, Donald Richards, Bernie Fox, David Jablons, Junko Aimi, Andy Lin and Kristen Hege
Mol Ther 13: S243-S243; doi:10.1016/j.ymthe.2006.08.706
632. Sustained Function and Enhanced Replicative Capacity of Anti-Tumor CD4+ Effectors by Enforced Co-Stimulation
Lufen Chang and Michael Jensen
Mol Ther 13: S243-S244; doi:10.1016/j.ymthe.2006.08.707
633. Improved Antitumoral Efficacy of Semliki Forest Virus Vectors Expressing IL-12 in Orthotopic Hepatocellular Carcinoma Models
Juan R. Rodriguez, Min Guan, Erkuden Casales, Jesus Prieto, Cheng Qian and Cristian Smerdou
Mol Ther 13: S244-S244; doi:10.1016/j.ymthe.2006.08.708
634. Engineered Herpes Simplex Virus Expressing IL-12 for the Treatment of Experimental Brain Tumors
Shinya Miyamoto, Yasushi Ino, Hiroshi Fukuhara and Tomoki Todo
Mol Ther 13: S244-S244; doi:10.1016/j.ymthe.2006.08.709
635. Systemic Oncolytic and Immunologic Therapy for Cancer with JX-594, a Targeted Poxvirus Expressing GM-CSF
David H. Kirn, Stephen Thorne, J.K. Kim, J.Y. Oh, B.H. Park, D.E. Lee, J.S. Kim, J.E. Je and Tae-Ho Hwang
Mol Ther 13: S244-S245; doi:10.1016/j.ymthe.2006.08.710
636. Antitumoral Activity Mediated by a Lipid- Based Gene Delivery System Containing Therapeutic Genes
Henrique Faneca, Ant|[oacute]|nio Cabrita, S|[eacute]|rgio Sim|[otilde]|es and Maria Pedroso de Lima
Mol Ther 13: S245-S245; doi:10.1016/j.ymthe.2006.08.711
637. Specific Oncolytic Adenovirus Driven by Human A33 Promoter Region for Colorectal Cancer Therapy
Eduardo G. Cafferata, Daniela R. Maccio, Maria V. Lopez, Diego L. Viale and Osvaldo L. Podhajcer
Mol Ther 13: S245-S245; doi:10.1016/j.ymthe.2006.08.713
638. The Optimal Placement and Orientation of the Bipartite Two-Step Transcription Amplification (TSTA) Expression System in Adenoviral Vectors for Prostate Cancer Gene Therapy
Marxa L. Figueiredo, Makoto Sato, May N. Chen, Russell Powell, Michael Carey, Sam Gambhir and Lily Wu
Mol Ther 13: S245-S246; doi:10.1016/j.ymthe.2006.08.714
639. In Vivo Imaging of Lymph Node Metastasis with Telomerase-Specific Replication-Competent Adenovirus Containing Green Fluorescent Protein Gene
Toru Kojima, Hiroyuki Kishimoto, Yuichi Watanabe, Shunsuke Kagawa, Fuminori Teraishi, Masayoshi Hioki, Yoshihiro Ikeda, Ryo Sakai, Yasuo Urata, Noriaki Tanaka and Toshiyoshi Fujiwara
Mol Ther 13: S246-S246; doi:10.1016/j.ymthe.2006.08.715
640. Oncolytic Transcriptionally Retargeted Adenovirus Expressing Nitroreductase in Combination with Antiangiogenic Drug RAD001
Alexander N. Lukashev, Krizstian G. Homicsko, Cristophe Fuerer and Richard Iggo
Mol Ther 13: S246-S246; doi:10.1016/j.ymthe.2006.08.716
641. Retargeting Adenoviruses to Surface Expressed Antigens on Oral Mucosa
Hester J.T. van Zeeburg, Aafke Huizenga, N. Korokhov, Victor W. van Beusechem and Ruud H. Brakenhoff
Mol Ther 13: S247-S247; doi:10.1016/j.ymthe.2006.08.717
642. Toxicological Findings with Oncolytic Adenovirus Vector VRX-007, Wild-Type Ad5, and a Replication-Defective Adenovirus Vector in Syrian Hamsters and C57BL/6 Mice
Karoly Toth, Jacqueline F. Spencer, Drew L. Lichtenstein, Ann E. Tollefson, Debabrata Patra, Jennifer M. Meyer, Elena Shashkova, Mohan Kuppuswamy, Konstantin Doronin, Debanjan Dhar, Maria A. Thomas, Louis A. Zumstein and William S.M. Wold
Mol Ther 13: S247-S247; doi:10.1016/j.ymthe.2006.08.718
643. Human Matrix Metalloproteinase-8 Gene Delivery Enhances the Oncolytic Activity of a Replicating Adenovirus
Jin Cheng, Harald Sauthoff, Yao Qi Huang, David I. Kutler, Sheila Heitner, William N. Rom and John G. Hay
Mol Ther 13: S248-S248; doi:10.1016/j.ymthe.2006.08.719
644. A Dual-Action Armed Replicating Adenovirus for the Treatment of Bone Metastases of Breast Cancer
James J. Cody and Joanne T. Douglas
Mol Ther 13: S248-S248; doi:10.1016/j.ymthe.2006.08.720
645. Combination of Oncolytic Adenovirotherapy and Bax Gene Therapy Does Not Augments Antitumor Efficacy
Masayoshi Hioki, Shunsuke Kagawa, Toshiya Fujiwara, Yoshihiro Ikeda, Toru Kojima, Ryo Sakai, Futoshi Uno, Fuminori Teraishi, Yoshiko Shirakiya, Yuichi Watanabe, Yuuri Hashimoto and Yasuo Urata
Mol Ther 13: S248-S249; doi:10.1016/j.ymthe.2006.08.721
646. Utilization of Human Mesenchymal Stem Cells for Delivery of Targeted Oncolytic Adenoviruses into Orthotopic Lung Tumors
Tanja Hakkarainen, Merja S|[auml]|rkioja, Petri Lehenkari, Susanna Miettinen, Timo Ylikomi, Anna Kanerva and Akseli Hemminki
Mol Ther 13: S249-S249; doi:10.1016/j.ymthe.2006.08.722
647. Evaluation of Dose, Scheduling, Combination with Chemotherapy and Specificity of Ad5/3 Fiber-Chimeric Oncolytic Adenoviruses for Treatment of Ovarian Cancer
Mari Raki, Lotta Kangasniemi, Anna Kanerva, Gerd Bauerschmitz, Helena Isoniemi, Krister Hockerstedt and Akseli Hemminki
Mol Ther 13: S249-S249; doi:10.1016/j.ymthe.2006.08.723
648. Transductionally Modified Oncolytic Adenoviruses for Treatment of Advanced Pancreatic Cancer
Tommi Pisto, Lotta Kangasniemi, Tanja Hakkarainen, Tuula Kiviluoto, Kilian Guse, Anna Kanerva and Akseli Hemminki
Mol Ther 13: S250-S250; doi:10.1016/j.ymthe.2006.08.724
649. Increased Therapeutic Efficacy of the Prostate-Specific Oncolytic Adenovirus Ad[I/PPT-E1A] by Introduction of the Entire E3 Region or the Adenovirus Death Protein
Angelika Danielsson, Helena Dzojic, Berith Nilsson, Wing-Shing Cheng and Magnus Essand
Mol Ther 13: S250-S250; doi:10.1016/j.ymthe.2006.08.725
650. AU-rich 3' UTR Elements for Increasing the Specificity of Promoter Regulated Adenoviral Gene Therapy
Merja Sarkioja, Minna Eriksson, Ristimaki Ari, Kanerva Anna, Hakkarainen Tanja and Hemminki Akseli
Mol Ther 13: S250-S250; doi:10.1016/j.ymthe.2006.08.726
651. VRX-007, an Oncolytic Adenovirus Vector, Replicates in Syrian Hamsters but Not Mice: Comparison of Biodistribution Studies Performed in the Syrian Hamster and Mouse
Drew L. Lichtenstein, Karoly Toth, Jaqueline F. Spencer, Jenifer Meyer, Baoling Ying, Ann E. Tollefson, Debabrata Patra, Elena Shashkova, Mohan Kuppuswamy, Konstantin Doronin, Debanjan Dhar, Louis A. Zumstein and William S.M. Wold
Mol Ther 13: S251-S251; doi:10.1016/j.ymthe.2006.08.727
652. In Vivo Evaluation of an Oncolytic Adenovirus Regulated by Hypoxia
Sergia Bortolanza, Jesus Prieto, Pilar Alzuguren, Elvira Carro and Ruben Hernandez-Alcoceba
Mol Ther 13: S251-S251; doi:10.1016/j.ymthe.2006.08.728
653. The Controlled Transgene Expression in Oncolytic Adenoviral Vectors with Major Late Promoter for Therapy of Cancer
Wei Jiang, Rong Cai, Guanghua Yang, Kai Chen, Yu Chen, Xinyuan Liu and Cheng Qian
Mol Ther 13: S251-S251; doi:10.1016/j.ymthe.2006.08.729
654. Targeting Adenoviral Vectors for Use in Breast Cancer Gene Therapy
Alan D. DeSilva, Leonard I. Wiebe, Chang-Xin Shi, Mabrouk M. Elgadi, Gianluca Bossi and Mary M. Hitt
Mol Ther 13: S252-S252; doi:10.1016/j.ymthe.2006.08.730
655. Development of a Human Carboxylesterase That Can Efficiently Metabolize CPT-11
Monika Wierdl, Randy M. Wadkins, Matthew R. Redinbo, Lyudmila Tsurkan and Philip M. Potter
Mol Ther 13: S252-S252; doi:10.1016/j.ymthe.2006.08.731
656. Combined Oncolysis and Anti-Angiogenesis Gene Therapy Using a Herpes Simplex Virus Expressing Endostatin in a Murine Lung Cancer Model
Michael Lanuti, Jonathan M. Goodwin and Kenneth K. Tanabe
Mol Ther 13: S252-S253; doi:10.1016/j.ymthe.2006.08.732
657. Combination Therapy with Cyclophosphamide and the Oncolytic Herpes Virus Mutant rRp450, Expressing a Cyclophosphamide Prodrug, Is Clinically Safe by Intratumoral, Intravenous, and Intracerebral Administration in an HSV-1 Susceptible Mouse Model
Mark A. Currier, Yonatan Y. Mahller, Greg Stroup, Hirokazu Kambara, E.A. Chiocca and Timothy P. Cripe
Mol Ther 13: S253-S253; doi:10.1016/j.ymthe.2006.08.733
658. Oncolytic Herpes Virus Mutants Are Efficacious Against Malignant Peripheral Nerve Sheath Tumor Xenografts
Yonatan Y. Mahller, Mark A. Currier, Margaret H. Collins, Nancy Ratner and Timothy P. Cripe
Mol Ther 13: S253-S254; doi:10.1016/j.ymthe.2006.08.734
659. Application of HSVtk Suicide Gene to X- SCID Gene Therapy: Ganciclovir Treatment Selectively Elmiinates Gene Corrected Cells In Vitro and In Vivo
Toru Uchiyama, Yoshinori Ishikawa, Naoto Ishii, Masafumi Onodera, Miki Sato, Yoji Sasahara, Nobuyuki Tanaka, Kazuo Sugamura, Satoru Kumaki and Shigeru Tsuchiya
Mol Ther 13: S254-S254; doi:10.1016/j.ymthe.2006.08.736
Abstracts
660. The Effect of the B2 Mutation on Hematopoietic Reconstitution in the French X-SCID Gene Therapy Trial
John T. Gray, Salima Hacein-Bey-Abina, Marina Cavazzana-Calvo and Alain Fischer
Mol Ther 13: S254-S255; doi:10.1016/j.ymthe.2006.08.737
661. Ex Vivo Pre-Selection of Transgenic Mouse Cells Expressing Green Fluorescent Protein-Methylguanine Methyltransferase P144K Fusion Protein Increases Marking Following Transplant into Wild Type Mice
Uimook Choi, Lanise Cardwell and Harry L. Malech
Mol Ther 13: S255-S255; doi:10.1016/j.ymthe.2006.08.738
662. Retroviral Insertion Site Analysis Following Therapeutic Gene Transfer of CD18 in a Canine Model of Leukocyte Adhesion Deficiency
Mehreen Hai, Thomas R. Bauer Jr., Laura M. Tuschong, Yuchen Gu, Robert A. Sokolic and Dennis D. Hickstein
Mol Ther 13: S255-S255; doi:10.1016/j.ymthe.2006.08.739
663. Gene Modified Human Mesenchymal Stem Cells Expressing Osteoprotegerin Reverse Osteoclast Activation in a Xenogeneic Murine Model of Multiple Myeloma
Neil Rabin, Chara Kyriakou, Arnold Pizzey, Clive Buckle, Matthew Prideaux, Peter Croucher, Amit Nathwani and Kwee Yong
Mol Ther 13: S256-S256; doi:10.1016/j.ymthe.2006.08.740
664. WHIM Syndrome Type Myelokathexis In Vivo in the NOD/SCID Mouse Model Following Transplant of Healthy Human Stem Cells Transduced with C-Terminus Truncated CXCR4
Toshinao Kawai, Uimook Choi, Lanise Cardwell, Suk See Deravin, Nora Naumann, Narda L. Whiting-Theobald, Gilda F. Linton, Sebastian Brenner, Philip M. Murphy and Harry L. Malech
Mol Ther 13: S256-S256; doi:10.1016/j.ymthe.2006.08.741
665. Novel Gammaretroviral Vectors for Gene Therapy of SCID-X1
Susannah I. Bailey, Steven J. Howe, Axel Schambach, Christine Kinnon, Christopher Baum and Adrian J. Thrasher
Mol Ther 13: S256-S257; doi:10.1016/j.ymthe.2006.08.742
666. Conversion of |[beta]|A- to |[beta]|S-Globin by Small Fragment Homologous Replacement (SFHR) in Hematopoietic Stem/Progenitor Cells (HSPCs)
Alireza Abdolmohammadi, Rosalie Maurisse, Babak Bedayat, David De Semir, Judy Wai-Men Cheung and Dieter C. Gruenert
Mol Ther 13: S257-S257; doi:10.1016/j.ymthe.2006.08.743
667. Gene Therapy for Beta Thalassemia: Preclinical Studies on Human Cells
Emanuela A. Roselli, Rossano Cesari, Annarita Miccio, Francesca Tiboni, Paola Corbella, Claudia Rossi, Erika Biral, Sarah Marktel, Michael Antoniou, Marco Andreani, Guido Lucarelli and Giuliana Ferrari
Mol Ther 13: S257-S257; doi:10.1016/j.ymthe.2006.08.744
668. Progress toward a Non-Viral Gene Therapy Protocol for the Treatment of Anemia
Magdolna G. Sebesty|[eacute]|n, Julia O. Hegge, Mark A. Noble, David L. Lewis, Hans Herweijer and Jon A. Wolff
Mol Ther 13: S257-S258; doi:10.1016/j.ymthe.2006.08.745
669. Drug Selection of Hematopoietic Cells by Regulated MGMT Activity
Barbara Verbeek, Thomas D. Southgate, Michael D. Milsom, Amanda J. Watson, Lorna B. Woolford, Geoff P. Margison and Leslie J. Fairbairn
Mol Ther 13: S258-S258; doi:10.1016/j.ymthe.2006.08.746
670. Combined Strategy of Minimal Myeloablation and Optimal BMT Regimen To Cure Murine |[beta]|-Thalassemia
Hady Felfly and Marie Trudel
Mol Ther 13: S258-S259; doi:10.1016/j.ymthe.2006.08.747
671. SIV-Derived Lentiviral Vectors Pseudotyped with Modified RD114 Envelope and Containing Mutant MGMT Efficiently Transduce Human CD34+ PBSCs and Allow Selection
Nora Naumann, Uimook Choi, Suk See De Ravin, Morvarid Moayeri, Larry Lantz, Lanise Cardwell-Miller and Harry L. Malech
Mol Ther 13: S259-S259; doi:10.1016/j.ymthe.2006.08.748
672. Lentiviral Vectors Targeting WASp Expression to Hematopoietic Cells, Efficiently Transduce CD34+ Cells and Correct Functions of Lymphocytes and Dendritic Cells from Wiskott-Aldrich Syndrome Patients
Sabine Charrier, Loic Dupre, Samantha Scaramuzza, Laurence Jeanson, Mike Blundell, Olivier Danos, Federica Cattaneo, Alessandro Aiuti, Adrian Thrasher, Maria-Grazia Roncarolo and Anne Galy
Mol Ther 13: S259-S259; doi:10.1016/j.ymthe.2006.08.749
673. Threshold of Normal Stem Cells for Successful Correction of Murine |[beta]|-Thalassemia
Hady Felfly and Marie Trudel
Mol Ther 13: S259-S260; doi:10.1016/j.ymthe.2006.08.750
674. Administration of rAAV2 and rAAV5 to the Parotid Gland of Non-Human Primates
A. Voutetakis, C. Zheng, J.A. Chiorini, M. Schmidt, S. Afione, M. Metzger, C. Dunbar, R.E. Donahue and B.J. Baum
Mol Ther 13: S260-S260; doi:10.1016/j.ymthe.2006.08.751
675. Correction of Anemia in Uremic Rats by Intramuscular Injection of Lentivirus Carrying an Erythropoietin Gene
Taekeun Oh, Guihong Quan, Haeyoung Kim, Frank Park and Seungtaik Kim
Mol Ther 13: S260-S261; doi:10.1016/j.ymthe.2006.08.752
676. AAV-Rep 78 Mediated Rescue and Integration of a 27kb Transgene Cassette
Hongjie Wang and Andre Lieber
Mol Ther 13: S261-S261; doi:10.1016/j.ymthe.2006.08.753
677. Generation and Application of an Efficient Chronic Myelogenous Leukemia (CML)-Targeted Recombinant Adeno-Associated Virus (rAAV) Vector: New Therapeutic Options?
Marlon R. Veldwijk, Marius Stiefelhagen, Juergen A. Kleinschmidt, Anna Jauch, Stephanie Laufs, Frederik Wenz, W. Jens Zeller and Stefan Fruehauf
Mol Ther 13: S261-S261; doi:10.1016/j.ymthe.2006.08.754
678. Production of a Novel Recombinant AAV Vector Containing beta-Globin Gene and Essential Segments of LCR and Transfer of the Construct into the CD133+, Mesenchymal Stem Cell and Unrestricted Somatic Stem Cell (USSCs)
Pedram Kharaziha, Mehdi Forouzandeh, Mohammad J. Rasaee, Masood Soleimani, Jafar Kyani and Mahboobeh Mohseni
Mol Ther 13: S262-S262; doi:10.1016/j.ymthe.2006.08.755
679. Gene Transfer to Hematopoietic Stem/Progenitor Cells Using SV40-Derived Vectors
Alena A. Chekmasova, Mahender Singh and David S. Strayer
Mol Ther 13: S262-S262; doi:10.1016/j.ymthe.2006.08.756
680. Non-Viral Transposon Mediated Gene Transfer of Human Factor VIII to Hemophilia A Mice
Litao Xie, Yubin Kang, Stephen Yant, Mark Kay and Paul McCray
Mol Ther 13: S262-S262; doi:10.1016/j.ymthe.2006.08.757
681. Inadvertent Transduction of Recipient Tissues after Transplantation of Ex Vivo Lentivirally Transduced Hematopoietic Cells
Yung-Wei Pan and Peter Kurre
Mol Ther 13: S263-S263; doi:10.1016/j.ymthe.2006.08.758
682. Collection and Genetic Correction of Fanconi Complement Type A Hematopoietic Stem Cells: Results of Two Pilot Studies
P.F. Kelly, B. Balcik, K. Bohn, R. Mueller, T. Schuesler, L. Reeves, T. Leemhuis, R. Harris, S.M. Davies, F.O. Smith, C. von Kalle and D.A. Williams
Mol Ther 13: S263-S263; doi:10.1016/j.ymthe.2006.08.759
683. Bronchoscope-Guided, Targeted Lobar Aersolization of HDAd into the Lungs of Nonhuman Primate Results in Exceedingly High Pulmonary Transduction Uniformally throughout the Entire Lung with Negligible Toxicity
Peter Hiatt, Nicola Brunetti-Pierri, Ruth McConnell, Donna Palmer, Julie Katkin, David Dimmock, Yu Zuo, Milton Finegold, Arthur Beaudet and Philip Ng
Mol Ther 13: S264-S264; doi:10.1016/j.ymthe.2006.08.761
684. Improved Performance of AAV6 in Airways In Vivo
Maria Limberis, Luk H. Vandenberghe, Julie C. Johnston, Di Wu, Deirdre McMenamin, Regina L. Munden and James M. Wilson
Mol Ther 13: S264-S265; doi:10.1016/j.ymthe.2006.08.762
685. Single-Dose Lentivirus Gene Transfer In Vivo Maintains Airway Gene Expression for over Six Months
Alice G. Stocker, Don S. Anson and David W. Parsons
Mol Ther 13: S265-S265; doi:10.1016/j.ymthe.2006.08.763
686. Exploring Different Formulations as a Strategy To Enhance Adenoviral Gene Delivery to the Lung
Rahul Kushwah, Benjamin H. Lee and Jim Hu
Mol Ther 13: S265-S265; doi:10.1016/j.ymthe.2006.08.764
687. In a Model of Irradiation Retreatment of the Murine Lung, Gene Therapy with Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Increases Lung Tolerance
Joel S. Greenberger, Yunyun Niu and Michael W. Epperly
Mol Ther 13: S266-S266; doi:10.1016/j.ymthe.2006.08.765
688. The Effects of Cyclic Stretch on Microtubule Stability and Exogenous Gene Expression in the Alveolar Epithelium
Christopher Geiger and David A. Dean
Mol Ther 13: S266-S266; doi:10.1016/j.ymthe.2006.08.766
689. Restriction Profiles of Primate TRIM5|[alpha]| on FIV
Douglas E. Dylla, Melissa A. Hickey, Theodora Hatziioannou, Paul D. Bieniasz and Paul B. McCray Jr.
Mol Ther 13: S266-S267; doi:10.1016/j.ymthe.2006.08.767
690. Gene Delivery Targeting CCR3 Using SV40-Derived Vectors: A Novel Therapeutic Approach for Allergic Diseases
Lokesh Agrawal and David S. Strayer
Mol Ther 13: S267-S267; doi:10.1016/j.ymthe.2006.08.768
691. Efficient Downregulation of ENaC Activity by Synthetic siRNAs
Christa M. Schmidt, Stephanie Huth, Olga Mykhaylyk, Christian Plank, Carsten Rudolph and Joseph Rosenecker
Mol Ther 13: S267-S267; doi:10.1016/j.ymthe.2006.08.769
692. Aerosol Delivery of Concentrated pDNA/PEI Formulations to the Murine Lung
Lee A. Davies, Stephen C. Hyde and Deborah R. Gill
Mol Ther 13: S267-S268; doi:10.1016/j.ymthe.2006.08.770
693. Airway Pre-Treatment with a Novel Surfactant Compound Improves Standard Enhancement of Lentiviral Gene Transfer In Vivo
Patricia L. Cmielewski, Don S. Anson and David W. Parsons
Mol Ther 13: S268-S268; doi:10.1016/j.ymthe.2006.08.771
694. Involvement of Glycosaminoglycans in VSV-G Pseudotyped Lentiviral Vector Mediated Gene Transfer into Airway Epithelial Cells
Elena Copreni, Lucia Palmieri, Salvatore Carrabino, Stefano Castellani, Luigi Naldini and Massimo Conese
Mol Ther 13: S268-S269; doi:10.1016/j.ymthe.2006.08.772
695. Low-Frequency Ultrasound Increases Non-Viral Lung Gene Transfer
Stefania Xenariou, Hai-Dong Liang, Uta Griesenbach, Jie Zhu, Raymond Farley, Lucinda Somerton, Charanjit Singh, Peter K. Jeffery, Ronald K. Scheule, Seng H. Cheng, Duncan M. Geddes, Martin Blomley and Eric W.F.W. Alton
Mol Ther 13: S269-S269; doi:10.1016/j.ymthe.2006.08.773
696. Development of Lipid/Peptide (Lip/Tide) Vectors for Respiratory Gene Transfer
Stephen L. Hart, Aris Tagalakis, Michele J. Writer, James Devaney, Helen C. Hailes, Alethea B. Tabor, John B. Wong, Steve Bottoms, Robin J. McAnulty, Ron Scheule, Seng Cheng and Adam Jaffe
Mol Ther 13: S269-S270; doi:10.1016/j.ymthe.2006.08.774
697. Molecular Forms of Feline Immunodeficiency Virus Following Gene Transfer to Airway Epithelia
Marisa Banasik, Christopher Moressi, Melissa Hickey, Todd Scheetz and Paul McCray
Mol Ther 13: S270-S270; doi:10.1016/j.ymthe.2006.08.775
698. Towards Non-Invasive Assessment of CF Airway Gene Therapy: High Resolution Propogation-Based Imaging of Airway Surface Liquid Via Synchrotron Light
David W. Parsons, Karen W. Siu, Jeffrey Crosbie, Ivan Williams, Boucher C. Richard, Kentaro Uesugi and Naoto Yagi
Mol Ther 13: S270-S270; doi:10.1016/j.ymthe.2006.08.776
699. Bactofection into Airway Epithelial Cells In Vitro and In Vivo Using a Genetically Modified Escherichia coli
Mia D.B. Larsen, Uta Griesenbach, Sylvie Goussard, Dieter Gruenert, Duncan M. Geddes, Catherine Grillot-Courvalin and Eric W.F.W. Altom
Mol Ther 13: S270-S271; doi:10.1016/j.ymthe.2006.08.777
700. Formulation of Chemically Modified Short Interfering RNA (siRNA) for Local Delivery to the Respiratory Tract
Paul B. McCray, Brent A. Dickinson, Kim C. Hartsough, Anna M. Gomez, Sharon F. Jamison, Tim R. Shadel, Jennifer A. Lockridge, Pam A. Pavco, Wei-min Wang, Tongqian Chen, Chandra Vargeese, David K. Tung, Christine L. Wohlford-Lenane and Ivan M. Richards
Mol Ther 13: S271-S271; doi:10.1016/j.ymthe.2006.08.778
701. Gene Delivery of PEI-DNA Complexes to the Lungs of Mice by Inhalation Is Mouse Strain-Dependent
Aurora Ortiz, Schillinger Ulrike, Dames Petra, Lesina Eugenia, Plank Christian, Rosenecker Joseph and Rudolph Carsten
Mol Ther 13: S271-S271; doi:10.1016/j.ymthe.2006.08.779
702. Use of Perfluorochemical Liquid Suspensions To Facilitate Gene Delivery to the Lung: Distribution of Recombinant Adenovirus- Delivered Transgene Expression
Marlene S. Strayer, Marla R. Wolfson, Daniel J. Malone, Jichuan Wu, Hshi-chi Koo, Thomas H. Shaffer, David S. Strayer, Jonathan M. Davis and Jeffrey A. Kazzaz
Mol Ther 13: S271-S272; doi:10.1016/j.ymthe.2006.08.780
703. Analysis of the Stability and Functionality of siRNA after Nebulization of siRNA Polyplexes
Stephanie Huth, Christa Schmidt, Carsten Rudolph and Joseph Rosenecker
Mol Ther 13: S272-S272; doi:10.1016/j.ymthe.2006.08.782
704. RNA Interference of Stat3 Using Adenovirus Vector Inhibits Pancreatic Cancer Growth In Vitro and In Vivo
Chen Huang, Ju Feng Zhang, Zheng Jun Qiu and Fang Zhang
Mol Ther 13: S272-S272; doi:10.1016/j.ymthe.2006.08.783
705. A Practical Approach to siRNA-Based Treatment Design Using Bioluminescent Imaging and Mathematical Modeling
Derek W. Bartlett and Mark E. Davis
Mol Ther 13: S272-S273; doi:10.1016/j.ymthe.2006.08.784
707. Real-Time Monitoring of Single-Stranded and Duplex Short Interfering RNA Integrity inside Living Cells
Koen Raemdonck, Katrien Remaut, Bart Lucas, Niek N. Sanders, Jo Demeester and Stefaan C. De Smedt
Mol Ther 13: S273-S273; doi:10.1016/j.ymthe.2006.08.786
708. Gene Targeting with Triplex-Forming Oligonucletides in the Pyrimidine Motif
Jennifer M. Kalish, Melissa P. Knauert, Denise C. Hegan and Peter M. Glazer
Mol Ther 13: S273-S274; doi:10.1016/j.ymthe.2006.08.787
709. Adeno-Associated Virus Delivery of siRNAs Leads to a Reduction in Phospholamban Levels
Lourdes M. Andino, Barry J. Byrne, Hideko Kasahara and Alfred S. Lewin
Mol Ther 13: S274-S274; doi:10.1016/j.ymthe.2006.08.788
710. Comparison of the Activity of siRNAs and shRNAs Against Furin: A Cellular Target for HIV-1 Inhibition
Pavlina Konstantinova, Olivier ter Brake, Rogier Sanders, Bart van Heertum and Ben Berkhout
Mol Ther 13: S274-S274; doi:10.1016/j.ymthe.2006.08.789
711. Allele-Specific Silencing of Mutant Huntingtin for Huntington's Disease Therapy
Alex Mas-Monteys, Scott Q. Harper, Brian L. Gilmore, Patrick D. Staber, Chris Schaffer, Barry Polisky, Chandra Vargeese and Beverly L. Davidson
Mol Ther 13: S274-S275; doi:10.1016/j.ymthe.2006.08.790
712. AAV-Mediated Allele-Specific RNA Interference of a Common Dominant Rhodopsin Mutation Causing Retinitis Pigmentosa
Alessandra Tessitore, Fabiana Parisi, Mariacarmela Allocca, Umberto Di Vicino, Michela A. Denti, Luciano Domenici, Irene Bozzoni and Alberto Auricchio
Mol Ther 13: S275-S275; doi:10.1016/j.ymthe.2006.08.791
713. NFkB Decoy Oligodeoxynucleotides Inhibit Osteoclast Differentiation and Activation In Vitro and Improve Osteoporosis of Ovariectomized and Vitamin C Difficient Rat Models
Hideo Shimizu, Hironori Nakagami, Natsuki Yasumasa, Rie Hanayama, Toshio Ogihara and Ryuichi Morishita
Mol Ther 13: S275-S275; doi:10.1016/j.ymthe.2006.08.792
714. Effect of Adenovirus-Mediated RNA Interference on Endogenous micro-RNA Functionality in a Mouse Model of Multidrug Resistance Protein-2 Gene Silencing
Oscar Aparicio, I|[ntilde]|igo Narvaiza, Maria Vera, Nerea Razquin, Jesus Prieto and Puri Fortes
Mol Ther 13: S275-S276; doi:10.1016/j.ymthe.2006.08.793
715. Targeted Delivery of Antisense Oligonucleotide and siRNA into Lung Cancer Cells
Shyh-Dar Li and Leaf Huang
Mol Ther 13: S276-S276; doi:10.1016/j.ymthe.2006.08.794
716. Differential Effects of Secondary Structure on Antisense Oligonucleotide (AON) and Short Interfering RNA (siRNA) Mediated mRNA Cleavage
Stephen I. Rudnick and Alan M. Gewirtz
Mol Ther 13: S276-S276; doi:10.1016/j.ymthe.2006.08.795
717. VCP Short Hairpin RNA Rescues |[Delta]|F508-CFTR and Suppresses IL8 Levels: Therapeutic Implications in Cystic Fibrosis
Neeraj Vij, Shengyun Fang and Pamela L. Zeitlin
Mol Ther 13: S276-S277; doi:10.1016/j.ymthe.2006.08.796
718. PTD-Fusion Peptide as a Delivery Vehicle for siRNA To Target HIV Reservoirs
Ashok Chauhan, Avindra Nath, Daivd Levy and Suzanne Gartner
Mol Ther 13: S277-S277; doi:10.1016/j.ymthe.2006.08.797
719. Specific Cancer Regression by Trans-Splicing Ribozyme-Mediated Replacement of K-RASV12 Transcript
Ju Hyun Kim, Sung Jin Kim, Sun Young Jang and Seong-Wook Lee
Mol Ther 13: S277-S277; doi:10.1016/j.ymthe.2006.08.798
720. Inhibition of Coxsackievirus B3 (CVB3) Replication by Self-Complementary AAV Vector-Based Expression of shRNAs Directed Against the RNA-Dependent RNA Polymerase of CVB3
Isaac Sipo, Xiaomin Wang, Jens Kurreck, Stefan Weger, Heinz Zeichhardt, Wolfgang Poller and Henry Fechner
Mol Ther 13: S277-S278; doi:10.1016/j.ymthe.2006.08.799
721. Antisense Oligonucleotide Therapy for Duchenne Muscular Dystrophy: From Cell Culture to Clinical Trial
Jignya Ashar, Terence Partridge and Qi L. Lu
Mol Ther 13: S278-S278; doi:10.1016/j.ymthe.2006.08.800
722. Silencing of Transforming Growth Factor-|[beta]| Receptor II by RNA Interference Suppresses Extracellular Matrix Production in Rat Hepatic Stellate Cells
Jin Wook Kim, Song-Qing He, Mark A. Zern, John J. Rossi and Jian Wu
Mol Ther 13: S278-S278; doi:10.1016/j.ymthe.2006.08.801
723. In Vivo Expansion of MDS1/EVI1, PRDM16 and SETBP1 Integration Clones in Successful Chronic Granulomatous Disease (CGD) Gene Therapy Trial
Kerstin Schwarzwaelder, Manfred Schmidt, Marion G. Ott, Stefan Stein, Hanno Glimm, Annette Deichmann, Ulrich Siler, Dieter Hoelzer, Reinhard Seger, Manuel Grez and Christof von Kalle
Mol Ther 13: S279-S279; doi:10.1016/j.ymthe.2006.08.803
724. Phase I Study of Replication-Competent Adenovirus-Mediated Suicide Gene Therapy in Combination with Conformal Radiotherapy for the Treatment of Intermediate- to High-Risk Prostate Cancer: Two Year Efficacy Results
Svend O. Freytag, Jae Ho Kim, Hans Stricker2, Jan Pegg, Stephen L. Brown and Mei Lu
Mol Ther 13: S279-S279; doi:10.1016/j.ymthe.2006.08.804
725. Correction of Laminin-5-Deficient Junctional Epidermolysis Bullosa by Transplantation of Genetically Modified Epidermal Stem Cells. A Phase-I Clinical Trial
Fulvio Mavilio, Stefano Ferrari, Francesca Di Nunzio, Giulietta Maruggi, Chiara Bonini, Sergio Capurro, Andrea Conti, Alberto Giannetti, Graziella Pellegrini and Michele De Luca
Mol Ther 13: S280-S280; doi:10.1016/j.ymthe.2006.08.805
726. Clinical Trial of Recombinant Adenovirus-p53 (Gendicine) Combined with Radiotherapy in Nasopharyngeal Carcinoma Patients
Shanwen Zhang, Shaowen Xiao, Yan Sun, Changqing Liu, Xing Su, Dongming Li, Gang Xu, Guangying Zhu and Bo Xu
Mol Ther 13: S280-S280; doi:10.1016/j.ymthe.2006.08.806
727. Improvements in Clinical and Radiographic Outcomes in a Phase I Study of AAV-GAD Gene Therapy for Parkinson's Disease
Michael G. Kaplitt, David Eidelberg, Andrew Feigin, Helen Fitzimmons, Patricia Lawlor, Kristin Strybing, Marie Cox, Chris Tang, Ross Bland and Matthew J. During
Mol Ther 13: S280-S281; doi:10.1016/j.ymthe.2006.08.807
728. Safety and Bioactivity of rAAV2-hAAT in alpha-1 Antitrypsin-Deficient Patients in a Phase I Clinical Trial
Mark L. Brantly, Terry Spencer, Carolyn T. Spencer, Thomas J. Conlon, Sihong Song, Margaret Humphries, Barry J. Byrne, Richard O. Snyder and Terence R. Flotte
Mol Ther 13: S281-S281; doi:10.1016/j.ymthe.2006.08.808
729. Phase I Trial of Intraperitoneal (IP) Administration of a Measles Virus (MV) Strain Expressing the Human Carcinoembryonic Antigen (CEA) in Ovarian Cancer Patients
Evanthia Galanis, Lynn C. Hartmann, William A. Cliby, Paula Zollman, Prema P. Peethambaram, Harry J. Long, Judith S. Kaur, Jeff A. Sloan, Gregory A. Poland, Kah-Whye Peng and Stephen J. Russell
Mol Ther 13: S281-S281; doi:10.1016/j.ymthe.2006.08.809
730. T Cell Responses to AAV Vector Capsid in Normal Donors and Subjects Who Have Undergone Liver-Directed AAV-Mediated Gene Transfer
Marcela V. Maus, Federico Mingozzi, Denise E. Sabatino, Daniel Hui, Margaret V. Ragni and Katherine A. High
Mol Ther 13: S282-S282; doi:10.1016/j.ymthe.2006.08.810
731. Hematopoietic Stem Cell Gene Transfer and Integration Site Analysis in Tumor-Prone Mice Uncovers Low Genotoxicity of Lentiviral Vector Integration
Eugenio Montini, Daniela Cesana, Manfred Schmidt, Francesca Sanvito, Maurilio Ponzoni, Lucia Sergi Sergi, Fabrizio Benedicenti, Cynthia Bartholomae, Clelia Di Serio, Claudio Doglioni, Christof von Kalle and Luigi Naldini
Mol Ther 13: S282-S282; doi:10.1016/j.ymthe.2006.08.812
732. Avian Sarcoma Leukosis Virus Vectors Can Transduce Rhesus Macaque HSCs and Result in a Potentially Safer Integration Profile
Jingqiong Hu, Andrea Ferris, Allen Krause, Robert E. Donahue, Stephen H. Hughes and Cynthia E. Dunbar
Mol Ther 13: S283-S283; doi:10.1016/j.ymthe.2006.08.813
733. Integration Site Distribution and Clonal Selection Related to the Insertion of Lentiviral SIN-Vectors
Cynthia C. Bartholomae, Manfred Schmidt, Rafael J. Yanez-Munoz, Steven J. Howe, Sonja Schmidt, Claudia Prinz, Adrian J. Thrasher and Christof von Kalle
Mol Ther 13: S283-S283; doi:10.1016/j.ymthe.2006.08.814
734. The Influence of Vector Design on Integration Site Selection by gamma-Retroviral and Lentiviral Vectors
Alessandra Recchia, Claudia Cattoglio, Annarita Miccio, Antonella Antonelli, Anna Testa, Giulia Facchini, Daniela Sartori, Giuliana Ferrari and Fulvio Mavilio
Mol Ther 13: S284-S284; doi:10.1016/j.ymthe.2006.08.815
735. VITA, a Method for the Analysis of Lentiviral Integration Patterns
Julie Mantovani, Nathalie Holic, Olivier Danos and Javier Perea
Mol Ther 13: S284-S284; doi:10.1016/j.ymthe.2006.08.816
736. Engineering Enhanced Retroviral and Lentiviral Vectors through the Selection of Peptide Insertion Libraries
Julie H. Yu and David V. Schaffer
Mol Ther 13: S284-S285; doi:10.1016/j.ymthe.2006.08.817
737. Efficient In Vivo Selection and Chemoprotection Following Drug Resistance Gene Therapy in a Nonmyeloablative Allogeneic Transplantation Setting in the Dog
Brian C. Beard, Sabine Gerull, Laura J. Peterson, Tobias Neff and Hans-Peter Kiem
Mol Ther 13: S285-S285; doi:10.1016/j.ymthe.2006.08.818
738. Towards Gene Correction of X-Linked SCID Using Engineered Zinc Finger Nucleases and Integrase Defective Lentiviral Delivery
Angelo Lombardo, Christian Beausejour, Fyodor D. Urnov, Jeffrey C. Miller, Alessandro Aiuti, Philip D. Gregory, Michael C. Holmes and Luigi Naldini
Mol Ther 13: S285-S285; doi:10.1016/j.ymthe.2006.08.819
739. Bioluminescent Virion Shells: A Novel Tool for Visualization of Viral Vectors in Animal Tissue
Aravind Asokan, Jarrod S. Johnson and Richard J. Samulski
Mol Ther 13: S286-S286; doi:10.1016/j.ymthe.2006.08.821
740. A Novel Hybrid System Efficiently Expands AAV Packaging Capacity
Arka Ghosh, Yongping Yue and Dongsheng Duan
Mol Ther 13: S286-S286; doi:10.1016/j.ymthe.2006.08.822
741. Self-Complementary Adeno-Associated Virus Vectors: Packaging Capacity and Purity
Jianqing Wu, Weihong Zhao, Li Zhong, Kenneth H. Warrington. Jr. and Arun Srivastava
Mol Ther 13: S286-S286; doi:10.1016/j.ymthe.2006.08.823
742. Molecular Evolution of Adeno-Associated Viral (AAV) Vectors Via DNA Family Shuffling of Primate and Non-Primate Serotypes
Dirk Grimm, Joyce S. Lee, Theresa A. Storm and Mark A. Kay
Mol Ther 13: S287-S287; doi:10.1016/j.ymthe.2006.08.824
743. Directed Evolution of Adeno-Associated Virus (AAV) by DNA Shuffling Yields Enhanced Gene Delivery Vectors
Wuping Li and Jude Richard Samulski
Mol Ther 13: S287-S287; doi:10.1016/j.ymthe.2006.08.825
744. Novel Vectors for Gene Therapy: Covering the Spectrum of Primate AAV Diversity
Luk H. Vandenberge, Katya Breous, Guang-Ping Gao, Deirdre McMenamin, Regina L. Munden, Tran Nguyen Duc and James M. Wilson
Mol Ther 13: S287-S288; doi:10.1016/j.ymthe.2006.08.826
745. AAV12, Isolated from Vervet Monkey, Has Unique Tropism and Biological as Well as Neutralization Properties
Michael Schmidt, Antonis Voutetakis, Sandra Afione, Changyu Zheng and John A. Chiorini
Mol Ther 13: S288-S288; doi:10.1016/j.ymthe.2006.08.827
746. Localization of Structural Determinants in AAV Capsid for Efficient Liver Transduction by Domain Swapping between AAV-2 and AAV-8
Xuan Shen, Hui Xu, Theresa Storm and Mark A. Kay
Mol Ther 13: S288-S288; doi:10.1016/j.ymthe.2006.08.828
747. Plasmid Electrotransfer of Eye Ciliary Muscle: Principle and Therapeutic Efficacy in an Acute Inflammatory Model
Carole Bloquel, R. Bejjani, Pascal Bigey, Fethi Bedioui, M. Doat, David BenEzra, Francine Behar-Cohen and Daniel Scherman
Mol Ther 13: S289-S289; doi:10.1016/j.ymthe.2006.08.830
748. Requirements for Microtubule-DNA Interactions during Cytoplasmic Trafficking of Plasmids
Erin E. Vaughan and David A. Dean
Mol Ther 13: S289-S289; doi:10.1016/j.ymthe.2006.08.831
749. Effective Plasmid DNA Dose Range and Promoters for Gene Expression in Muscle Following Hydrodynamic Limb Vein Delivery of pDNA into Rodents and Primates
Christine I. Wooddell, Julia O. Hegge, Guofeng Zhang, Patricia Kleinpeter, Magdolna G. Sebesty|[eacute]|n, Mark A. Noble, Loretta V. Pfannes, Hans Herweijer, Serge Braun, Thierry Huss and Jon A. Wolff
Mol Ther 13: S289-S290; doi:10.1016/j.ymthe.2006.08.832
750. Coelectrotransfer to Spinal Cord of Three Plasmids Coding for Pain Killer Gene and Regulatory Factors of the Tetracycline-Inducible System to Achieve Tightly Regulated Expression, Inhibition of Thermal Hyperalgesia, and Mechanical Allodynia
Chung-Ren Lin, Chien-Cheug Liu, Yi-Shen Chen and H-T Huang
Mol Ther 13: S290-S290; doi:10.1016/j.ymthe.2006.08.833
751. Magnetic Microbubbles: New Carriers for Localized Gene and Drug Delivery
Dialekti Vlaskou, Olga Mykhaylyk, Riccardo Giunta, Iva Neshkova, Nicole Hellwig, Florian Kroetz, Christian Bergemann and Christian Plank
Mol Ther 13: S290-S290; doi:10.1016/j.ymthe.2006.08.834
752. Delivery of Non-Microparticle Naked DNA Vaccine Using Supersonic Flow by a Low-Pressure Gene Gun
Chi-Chen Lin, Ying-Chang Wang, Men-Chi Yen and Ming-Derg Lai
Mol Ther 13: S291-S291; doi:10.1016/j.ymthe.2006.08.835
753. Ectopic Bone Formation In Vivo Induced by Sonoporation: Ultrasound-Based Non Viral Gene Delivery System
Dima Sheyn, Gadi Pelled, Yoram Zilberman, Zulma Gazit and Dan Gazit
Mol Ther 13: S291-S291; doi:10.1016/j.ymthe.2006.08.836
754. Volumetry of Mouse Liver during and after Hydrodynamic Injection
Takeshi Suda and Dexi Liu
Mol Ther 13: S292-S292; doi:10.1016/j.ymthe.2006.08.837
755. Phase II Clinical Trial Demonstrates the Safety and Tolerability of Multiple Doses of Autologous CD4+ T Cells Transduced with VRX496, a Lentiviral Vector Delivering Anti-HIV Antisense in Patients Failing 1 or More HAART Treatment
Tessio Rebello, Cathy Afable, Sherri Callahan, Laurent Humeau, Arvind Chopra, Xiaobin Lu and Vladimir Slepushkin
Mol Ther 13: S292-S292; doi:10.1016/j.ymthe.2006.08.839
756. Targeting Viral Entry in Gene Therapy of HIV-Infection
Jan van Lunzen, Tobias Glaunsinger, Felix Hermann, Klaus Kuehlcke, Alexander Alexandrov and Dorothee von Laer
Mol Ther 13: S293-S293; doi:10.1016/j.ymthe.2006.08.840
757. Engineered Expression of Novel TRIM5 Isoforms Inhibits HIV-1 Infection in CD34 Hematopoietic Stem Cell Derived Macrophages
Joseph S. Anderson and Ramesh Akkina
Mol Ther 13: S293-S293; doi:10.1016/j.ymthe.2006.08.841
758. Towards Gene Knock out Therapy for AIDS/HIV: Targeted Disruption of CCR5 Using Engineered Zinc Finger Protein Nucleases (ZFNs)
Elena Perez, Yann Jouvenot, Jeffrey C. Miller, Olga Liu, Jianbin Wang, Dmitry Guschin, Victor Bartsevich, Kenneth Kim, Ya-Li Lee, Edward J. Rebar, Dale Ando, Philip D. Gregory, James Riley, Michael C. Holmes and Carl June
Mol Ther 13: S293-S293; doi:10.1016/j.ymthe.2006.08.842
759. In Search of an Effective Target: In Vivo Approach Using HIV-1 Specific siRNA and Ribozyme Libraries
Hoshang J. Unwalla, Atilla A. Seyhan, Brian H. Johnston and John J. Rossi
Mol Ther 13: S293-S294; doi:10.1016/j.ymthe.2006.08.843
760. Overcoming Rhesus Macaque Endogenous Restriction Factors during HIV-1 Vector Transduction
Christina H. Swan, Udayan Chatterji, Philippe Gallay, Louis J. Picker and Bruce E. Torbett
Mol Ther 13: S294-S294; doi:10.1016/j.ymthe.2006.08.844
761. Genotoxicity Free Intranasal Gene Vaccines for Alzheimer's Disease and AIDS with Remarkable Efficacy in Model Animals; Use of a Cytoplasmic RNA Vector, Sendai Virus Vectors
Makoto Inoue, Hideo Hara, Tetsuro Matano, Yumiko Tokusumi, Yoshikazu Yonemitsu, Natsuko Kurosawa, Takumi Kanaya, Takashi Hironaka, Yoshiyuki Nagai, Takeshi Tabira and Mamoru Hasegawa
Mol Ther 13: S294-S295; doi:10.1016/j.ymthe.2006.08.845
762. Inhibition of HIV-1 Replication by Simian Intrinsic Restriction Factors, TRIM5alpha and APOBEC3G
Ryuta Sakuma, Josh A. Noser and Yasuhiro Ikeda
Mol Ther 13: S295-S295; doi:10.1016/j.ymthe.2006.08.846
763. Multimodality Imaging of Genetically Modified Lymphocytes In Vivo
Konstantin Dobrenkov, Malgorzata Dabrowska, Larissa Shenker, Elena Vider, Gertrude Gunset, Michel Sadelain and Vladimir Ponomarev
Mol Ther 13: S295-S295; doi:10.1016/j.ymthe.2006.08.848
764. Attenuation of Treg Cells by GITR Ligand Led to Synergistic Enhancement of Treatment Efficacy with Immune-Stimulatory Therapies in Mice Bearing Metastatic 4T1 Breast Carcinoma
Li Chen, Tian-gui Huang, Marcia Meseck and Savio L.C. Woo
Mol Ther 13: S295-S296; doi:10.1016/j.ymthe.2006.08.849
765. Suicide Gene Therapy by Central Memory Human T Lymphocytes
Shin Kaneko, Sara Mastaglio, Attilio Bondanza, Maurilio Ponzoni, Luca Aldrighetti, Salvatore Toma, Marina Radrizzani, Simona La Seta, Fabio Ciceri, Claudio Bordignon and Chiara Bonini
Mol Ther 13: S296-S296; doi:10.1016/j.ymthe.2006.08.850
766. Immunotherapy for Her2-Positive Medulloblastoma: Regression of Experimental Tumors by Transfer of Her2-Redirected T Cells In Vivo
Nabil M. Ahmed, Maheshika K. Ratnayake, Barbara Savoldo, Laszlo Perlaky, Gianpietro Dotti, Winfried Wels, Meenakshi B. Bhattacharjee, H. David Shine, Cliona M. Rooney, Helen E. Heslop and Stephen Gottschalk
Mol Ther 13: S296-S296; doi:10.1016/j.ymthe.2006.08.851
767. Genetic Engineering of an Immortal Human CD8+ T Cell Line
Stephanie Jones, Cary Hsu, Richard Morgan and Steven Rosenberg
Mol Ther 13: S297-S297; doi:10.1016/j.ymthe.2006.08.852
768. Redirected T Cells to Selectively Target Mature B Cell Derived Malignancies
Juan Vera, Barbara Savoldo, Stephane Vigouroux, Ettore Biagi, Martin Pule, Claudia Rossig, Malcolm Brenner and Gianpietro Dotti
Mol Ther 13: S297-S297; doi:10.1016/j.ymthe.2006.08.853
769. Genes Encoding Receptors, Signal Transducers and Transcription Regulators are Preferred Targets of Retroviral Vector Integration in T-Lymphocytes In Vitro and In Vivo
Frank A. Giordano, Boris Fehse, Agnes Hotz-Wagenblatt, Sunitha Jonnakuty, Coral Del Val, Jens-Uwe Appelt, Katalin Z. Nagy, Klaus Kuehlcke, Sonja Naundorf, Axel R. Zander, W. Jens Zeller, Stefan Fruehauf and Stephanie Laufs
Mol Ther 13: S297-S298; doi:10.1016/j.ymthe.2006.08.854
770. Selective Elimination of Alloreactive GVHD-Mediating Donor T Cells by Ex Vivo sFasL Treatment
Osnat Bohana-Kashtan, Hyam I. Levitsky and Curt I. Civin
Mol Ther 13: S298-S298; doi:10.1016/j.ymthe.2006.08.855
771. Human mda-7/Interleukin 24 (IL-24) Protein Kills Breast Cancer Cells Via the IL-20 Receptor and is Antagonized by IL-10
Minghong Zheng, Dora Bocangel, Abner Mhashilkar, Rajagopal Ramesh, Kelly K. Hunt, Suhendan Ekmekcioglu, Nancy Poindexter, Elizabeth A. Grimm and Sunil Chada
Mol Ther 13: S298-S298; doi:10.1016/j.ymthe.2006.08.857
772. Inhibition of Ovarian Tumor Growth Following Treatment with an Oncolytic Vaccinia Virus
Xiang Da Dong (Eric), Mark E. O'Malley, Sri Chalikonda1, Zongsheng Guo, Herbert J. Zeh and David L. Bartlett
Mol Ther 13: S298-S299; doi:10.1016/j.ymthe.2006.08.858
773. Chemoprotection of Mouse Marrow Transplant Recipients by Ex Vivo Lentiviral Transduction of Murine tyr22 Dihydrofolate Reductase Conferring Resistance to Methotrexate
Jennifer L. Gori, Kelly Podetz-Pederson, Debra Swanson, Andrea D. Karlin, Nikunj V. Somia and R. Scott McIvor
Mol Ther 13: S299-S299; doi:10.1016/j.ymthe.2006.08.859
774. Evaluation of Adenovirus Vectors Containing Serotype 35 Fibers for Gene Therapy of Cervical Cancer
Ying Liu, Pavel Sova, Robert Strauss, Sebastian Tuve, Janice Morihara, Nancy Kiviat, Papa Toure, Salif Sow and Andre Lieber
Mol Ther 13: S299-S300; doi:10.1016/j.ymthe.2006.08.860
775. Folate Receptor Targeted Virotherapy of Ovarian Cancer Using a Tropism Modified Measles Virus
Kosei Hasegawa, Takafumi Nakamura, Mary Harvey, Yashiro Ikeda, Ann Oberg, Mariangela Figini, Silvana Canevari, Lynn Hartmann and Kah-Whye Peng
Mol Ther 13: S300-S300; doi:10.1016/j.ymthe.2006.08.861
776. Evaluation of an Ad5/35-Based Oncolytic Adenovirus Vector Formulated in Icodextrin Delivery Solution in a Model of Ovarian Cancer
Sudesh Kothari, Shaoheng Ni, Robert Strauss and Andre Lieber
Mol Ther 13: S300-S300; doi:10.1016/j.ymthe.2006.08.862
777. A Novel Pan-Oncolytic Adenovirus Therapeutically Effective in Different Cancer Cell Types
Maria V. Lopez, Diego Viale, Eduardo G. Cafferata, Daniela R. Macio, David Gould, Yuti Chernajovsky and Osvaldo L. Podhajcer
Mol Ther 13: S300-S301; doi:10.1016/j.ymthe.2006.08.863
778. A Novel Genetically Modified Adenovirus Vector Shows Enhanced Infectivity towards Ex Vivo Pancreatic Cancer
Michael van Geer, Piter Bosma, Koert Kuhlmann, Conny Bakker, Dirk Gouma and Ronald Oude Elferink
Mol Ther 13: S301-S301; doi:10.1016/j.ymthe.2006.08.864
779. Genetic Delivery of an Anti-RSV Antibody Protects Against Pulmonary Infection with RSV in Mice
Chani Traube, Adriana Heguy, Bishnu De, Anja Krause, James M. Wilson, Ronald G. Crystal and Stefan Worgall
Mol Ther 13: S301-S302; doi:10.1016/j.ymthe.2006.08.866
780. Inhibition of Respiratory Syncytial Virus Gene Expression and Replication by 27mer Dicer Substrate siRNAs
Anthony J. Fischer, Christine L. Wohlford-Lenane, Scott D. Rose, Steven M. Varga, Mark A. Behlke and Paul B. McCray Jr
Mol Ther 13: S302-S302; doi:10.1016/j.ymthe.2006.08.867
781. Adenoviral Gene Transfer of Angiopoietin-1 Corrects Post-Pneumonectomy Compensatory Lung Growth in the MMP-9-/- Mice Via Mobilization of Endothelial Progenitor Cells
A. Marwan, S. Vaikunth, J. Parvadia, U. Harkness, A. Maldonado, M. Ripberger, B. Kalinowska, D. Alaee, E. Uzvolgyi and T. Crombleholme
Mol Ther 13: S302-S302; doi:10.1016/j.ymthe.2006.08.868
782. Long-Term Expression of EIAV Lentivectors Pseudotyped with Influenza Virus Spike Glycoproteins after Nasal Delivery to Mice
Angela M. Giddings, Manij Patel, Lawrence E. Ostrowski and John C. Olsen
Mol Ther 13: S303-S303; doi:10.1016/j.ymthe.2006.08.869
783. Correction of |[beta]|c-Deficient Pulmonary Alveolar Proteinosis (PAP) by Hematopoietic Stem Cell Gene Transfer in a Murine Model
V. Kleff, U.R. Sorg, C. Bury, B. Opalka, M. Flasshove, U. Dirksen and T. Moritz
Mol Ther 13: S303-S303; doi:10.1016/j.ymthe.2006.08.870
784. Sleeping Beauty-Mediated eNOS Gene Therapy Attenuates Monocrotaline-Induced Pulmonary Hypertension
Li Liu, Hanzhong Liu, Gary Visner and Bradley S. Fletcher
Mol Ther 13: S303-S304; doi:10.1016/j.ymthe.2006.08.871
785. A Novel Adeno Associated Virus Vector That Efficiently Transduces Airway Epithelium In Vivo and Can Be Re-Administered
Maria Limberis, Roberto Calcedo, Julio SanMiguel, Julie C. Johnston, Deirdre McMenamin, Peter L. Bell and James M. Wilson
Mol Ther 13: S304-S304; doi:10.1016/j.ymthe.2006.08.872
786. Development of Zero-CpG Plasmids with Reduced Inflammatory Responses Following Delivery of Lipid/pDNA Complexes to the Mouse Lung
Ian A. Pringle, Syahrilnizam Abdullah, Anna E. Lawton, Anusha Varathalingam, Nelson S. Yew, Seng H. Cheng, Deborah R. Gill and Stephen C. Hyde
Mol Ther 13: S304-S305; doi:10.1016/j.ymthe.2006.08.873
787. Engineered Fok I Heterodimers for Enhanced Zinc Finger Nuclease Specificity
Jeffrey C. Miller, Michael Holmes, Jianbin Wang, Ya-Li Lee, Igor Rupniewski, Adam Waite, Dmitry Guschin, Philip Gregory, Carl O. Pabo and Edward J. Rebar
Mol Ther 13: S305-S305; doi:10.1016/j.ymthe.2006.08.875
788. Engineered Zinc Finger Protein Transcription Factors as a Potential Therapy for Choroidal Neovascularization
Steve Zhang, Shu Kachi, Sean F. Hackett, Michido Kachi, Hideo Akiyama, Naoyasu Umeda, Katsutoshi Yokoi, Pei-qi Liu, Gabor Veres, Philip D. Gregory and Peter A. Campochiaro
Mol Ther 13: S305-S305; doi:10.1016/j.ymthe.2006.08.876
789. Regulated VEGF Expression Modulates Bone Formation Elicited by Muscle Stem Cells Expressing BMP4
Andrew Ho, Arvydas Usas, Hairong Peng, Brian Gearhart and Johnny Huard
Mol Ther 13: S306-S306; doi:10.1016/j.ymthe.2006.08.877
790. Murine Retroviral but Not Human Cellular Promoters Induce In Vivo Erythroid-Specific Promoter Deregulation That Can Be Prevented by Insulators
Elodie Robert, Emmanuel Richard, Cecile Ged, Punam Malik, Hubert De Verneuil and Francois Moreau-Gaudry
Mol Ther 13: S306-S306; doi:10.1016/j.ymthe.2006.08.878
791. Unraveling Disease-Inducible Promoters from Gene Expression Profiling for Therapeutic Application in Arthritis
Jeroen Geurts, Onno J. Arntz, Miranda B. Bennink, Leo A. Joosten, Wim B. van den Berg and Fons A. van de Loo
Mol Ther 13: S306-S307; doi:10.1016/j.ymthe.2006.08.879
792. Post-Integrative Gene Silencing in the Sleeping Beauty Transposition System
Brian S. Garrison, Stephen R. Yant, Jacob G. Mikkelsen and Mark A. Kay
Mol Ther 13: S307-S307; doi:10.1016/j.ymthe.2006.08.880
793. Induction of Molecular Chimerism in NOD Mice Is Resistant to the Occurrence of Type I Diabetes Induced by Blockade of the Programmed Death-1 Pathway
Chaorui Tian, Jessamyn Bagley, Mohammed Javeed I. Ansari, Mohamed Sayegh and John Iacomini
Mol Ther 13: S307-S308; doi:10.1016/j.ymthe.2006.08.881
794. Retroviral-Based Gene Therapy with Cyclo-Oxygenase-2 Promotes Bony Union and Accelerates Fracture Healing in the Rat
Charles H. Rundle, Donna D. Strong, Shin-Tai Chen, Matilda H.-C. Sheng, Jon E. Wergedal, K.-H. William Lau and David J. Baylink
Mol Ther 13: S308-S308; doi:10.1016/j.ymthe.2006.08.882
795. RNA Interference of Influenza Virus Infection
Jianzhu Chen, Qing Ge, James Lu and Eisen N. Herman
Mol Ther 13: S308-S308; doi:10.1016/j.ymthe.2006.08.884
796. Pol II-Driven shRNA as an Effective Hepatitis B Virus Therapeutic
Jeffery C. Giering, Dirk Grimm, Theresa A. Storm, Hui Xu and Mark A. Kay
Mol Ther 13: S308-S309; doi:10.1016/j.ymthe.2006.08.885
797. Long-Term Inhibition of Hepatitis B Virus in Transgenic Mice by Adeno-Associated Virus- Delivered Short Hairpin RNA
Chun-Chi Chen, Tai-Ming Ko, Hsin-I Ma, Hui-Lin Wu, Xiao Xiao and Mi-Hua Tao
Mol Ther 13: S309-S309; doi:10.1016/j.ymthe.2006.08.886
798. Anti-Influenza-Viral Efficacy Attributed to siRNA Formulated as Simple Lipoplex or PEI Polyplexes Is a Result of Their Immunostimulatory Properties
Marjorie Robbins, Ellen Ambegia, Matthew Fedoruk, Lorne Palmer, Kevin McClintock, Adam Judge and Ian MacLachlan
Mol Ther 13: S309-S309; doi:10.1016/j.ymthe.2006.08.887
799. Expressed Long Hairpin RNA Sequences Inhibit HBV Replication In Vivo without Inducing an Interferon Response
Abdullah Ely, Sergio Carmona, Carol Crowther, Steven Mufamadi, Samantha Barichievy, Marc Weinberg and Patrick Arbuthnot
Mol Ther 13: S309-S310; doi:10.1016/j.ymthe.2006.08.888
800. Complete Suppression of CCR5 Expression and Inhibition of HIV-1 Infection by Transfected and Lentiviral Vector Expressed shRNAs
Joseph S. Anderson, Annaleen Vermeulen, Jon Karpilow and Ramesh Akkina
Mol Ther 13: S310-S310; doi:10.1016/j.ymthe.2006.08.889
801. RNA Gene Therapy Targeting Herpes Simplex Virus
Jia Liu, Sonal S. Tuli, David C. Bloom, Gregory S. Schultz, Steve C. Ghivizzani and Alfred S. Lewin
Mol Ther 13: S310-S310; doi:10.1016/j.ymthe.2006.08.890
802. Silencing of HIV-1 with RNA Interference: A Multiple shRNA Approach
Olivier ter Brake and Ben Berkhout
Mol Ther 13: S310-S311; doi:10.1016/j.ymthe.2006.08.891
803. Endogenous microRNA Regulation Suppresses Transgene Expression in Hematopoietic Lineages and Enables Stable Gene Transfer
Brian D. Brown, Mary Anna Venneri, Anna Zingale, Lucia Sergi Sergi and Luigi Naldini
Mol Ther 13: S311-S311; doi:10.1016/j.ymthe.2006.08.1224
804. In Vivo Correction of a Metabolic Liver Disease by AAV8-Mediated Homologous Recombination
Karsten Wursthorn, Terry Storm, Mark A. Kay, Milton Finegold and Markus Grompe
Mol Ther 13: S311-S312; doi:10.1016/j.ymthe.2006.08.1225
805. Fatality in Mice Due to Oversaturation of Cellular Micro/Short Hairpin RNA Pathways
Dirk Grimm, Konrad L. Streetz, Theresa A. Storm, Catherine L. Jopling, Joyce S. Lee and Mark A. Kay
Mol Ther 13: S312-S312; doi:10.1016/j.ymthe.2006.08.1226
806. Immunologic Improvement after Gene Therapy in 3 Preadolescents with X-Linked Severe Combined Immunodeficiency (XSCID)
Javier Chinen, Joie Davis, Suk-See de Ravin, Gilda Linton, Amy Hsu, B. Nora Naumann, Effie Nomicos, Christopher Silvin, Narda Theobald-Whiting, Jean Ulrick, Harry Malech and Jennifer Puck
Mol Ther 13: S312-S312; doi:10.1016/j.ymthe.2006.08.1227
807. NADPH-Dependent Endosomal ROS Is Critical for rAAV Capsid Processing during Infection
Liang N. Zhang, Jennifer Marden, Ziying Yan and John F. Engelhardt
Mol Ther 13: S313-S313; doi:10.1016/j.ymthe.2006.08.1228
808. Optimizing Non-Primate Lentiviral Vectors for Gene Transfer of CFTR to Airway Epithelia
Jessica D. Goreham-Voss, Patrick L. Sinn, Melissa A. Hickey, Ariadna Arias and Paul B. McCray Jr.
Mol Ther 13: S313-S313; doi:10.1016/j.ymthe.2006.08.893
809. Suppression of Human Pancreatic Cancer Growth by Lentiviral Vector-Mediated Gene Transfer of Pigment Epithelium Derived Factor (PEDF)
Pranay D. Khare, Nils Loewen and Eric M. Poeschla
Mol Ther 13: S313-S314; doi:10.1016/j.ymthe.2006.08.894
810. Comparison of Anti-HIV Activity from Various Lentiviral Vectors Carrying Anti-HIV shRNA In Vitro
Shirley Li, Haitang Li, Daniela Castanotto, Keith Meinking, Guihua Sun, John A. Zaia and John J. Rossi
Mol Ther 13: S314-S314; doi:10.1016/j.ymthe.2006.08.895
811. Correction of Laminin-5 |[beta]|3 Chain Deficiency in Human Epidermal Stem Cells by Transcriptionally Targeted Lentiviral Vectors
Francesca Di Nunzio, Giulietta Maruggi, Stefano Ferrari, Marcela del Rio, Fernando Larcher, Michele De Luca and Fulvio Mavilio
Mol Ther 13: S314-S315; doi:10.1016/j.ymthe.2006.08.896
812. Cellular Delivery of Gene Therapy Vectors
Jian Qiao, Hongxun Wang, Rosa Maria Diaz, Atique Ahmed, Jill Thompson and Richard Vile
Mol Ther 13: S315-S315; doi:10.1016/j.ymthe.2006.08.897
813. Targeted Delivery of Biotinylated Compounds by Lodavin|[trade]|, LDL-Receptor |[ndash]| Avidin Fusion Protein, Expressing Lentivirus
Hanna P. Lesch, Jere T. Pikkarainen, Thomas Wirth, Minna U. Kaikkonen, Olli H. Laitinen, Kari J. Airenne and Seppo Yla- Herttuala
Mol Ther 13: S315-S315; doi:10.1016/j.ymthe.2006.08.898
814. Biomaterial-Mediated Retroviral Gene Delivery
Charles A. Gersbach, Sean R. Coyer, Joseph M. Le Doux and Andres J. Garcia
Mol Ther 13: S315-S316; doi:10.1016/j.ymthe.2006.08.899
815. 293 FLEX a New Cell Line for Fast, Reproducible and Efficient Production of Retroviral Gene Therapy Vectors
Ana S. Coroadinha, Paula M. Alves and Manuel J.T. Carrondo
Mol Ther 13: S316-S316; doi:10.1016/j.ymthe.2006.08.900
816. Rapid, Consistent and Scalable Production of Viral Vectors in Suspension Cells by Cotransfection of Viral Component Plasmid DNA or RNA
James Brady, Rama Shivakumar, Matthew Malehorn, Stephanie Feller, Cornell Allen, Linhong Li, Nicholas Chopas, Sergey Dzekunov, Madhusudan V. Peshwa and Linda N. Liu
Mol Ther 13: S317-S317; doi:10.1016/j.ymthe.2006.08.901
817. Rapid and Efficient Titration of Retroviral Vectors Using Quantitative Real-Time PCR
Seung Shin Yu, Kazuyuki Dan, Takashi Ueno, Junichi Mineno and Ikunosin Kato
Mol Ther 13: S317-S317; doi:10.1016/j.ymthe.2006.08.902
818. Development of Packaging Cell Lines for the Large-Scale Production of High-Titer Clinical Grade Recombinant Retroviruses
Karim Ghani and Manuel Caruso
Mol Ther 13: S317-S318; doi:10.1016/j.ymthe.2006.08.903
819. EGF Ligands Decrease Retroviral Gene Transfer through Protein Kinase C-delta
Raghvendra Singh and Stelios T. Andreadis
Mol Ther 13: S318-S318; doi:10.1016/j.ymthe.2006.08.904
820. Development of Efficient Self-Inactive Retroviral Vectors
Jaehyung Yoon, Vivian P. Yip, Lillian G. Yun, J.Kelly Ganjei and Youngsuk Yi
Mol Ther 13: S318-S318; doi:10.1016/j.ymthe.2006.08.905
821. Successful Adaptation of the RCAS-TVA Gene Transfer System for Use in a Bovine Mammary Epithelial Cell Culture Model
Peta M. Phillips, Peter C. Wynn and Paul A. Sheehy
Mol Ther 13: S318-S318; doi:10.1016/j.ymthe.2006.08.906
822. Lentiviral Vector Delivery of the RheoSwitch|[reg]| Therapeutic System for Inducible Therapeutic Transgene Expression
Zhijian J. Chen and Malla Padidam
Mol Ther 13: S319-S319; doi:10.1016/j.ymthe.2006.08.907
823. SLC350F2 Transporter Protein Is the Receptor Targeted by a Library-Selected Retroviral Envelope
Anindita Sarangi, Keith Bupp and Monica J. Roth
Mol Ther 13: S319-S319; doi:10.1016/j.ymthe.2006.08.908
824. Control of Splicing Efficiency by the Mouse Histone H2a Element in an MLV-Based Retroviral Vector
Jun-Tae Lee, Seung Shin Yu, V. Narry Kim, Joong-Gon Kim, Youngtae Hong, Sujeong Kim, Karim Lee, Sun Mee Bae, Kyung Mi Koh, Hye Lim Cho and Sunyoung Kim
Mol Ther 13: S319-S319; doi:10.1016/j.ymthe.2006.08.909
825. Primary Canine Marrow Cells Support HIV-1 Vector Mediated Expression of Functional Human Factor VIII
Michail Zaboikin, Srinivas N. Kumar, Tatiana Zaboikina and Friedrich G. Schuening
Mol Ther 13: S319-S320; doi:10.1016/j.ymthe.2006.08.910
826. Transduction of Human Hematopoietic Stem Cells by RD114-TR-Pseudotyped Lentiviral Vectors
Anna A. Stornaiuolo, Francesca F. Di Nunzio, Bianca B. Piovani, Francois F.-L. Cosset and Fulvio F. Mavilio
Mol Ther 13: S320-S320; doi:10.1016/j.ymthe.2006.08.911
827. Oncogenesis Following Delivery of Lentiviral Vectors to Fetal and Neonatal Mice
Michael Themis, Simon N. Waddington, Manfred Schmidt, Christof von Kalle, Yoahe Wang, Faisal Al-Allaf, Lisa Gregory, Megha Nivsarkar, Matthew Themis, Maxine Holder, Suzanne M.K. Buckley, Niraja Dighe, Alaine Ruthe, Ajay Mistry, Brian Bigger, Adrian J. Thrasher and Charles Coutelle
Mol Ther 13: S320-S320; doi:10.1016/j.ymthe.2006.08.912
828. Promoter Strength Versus Transactivation Potential: Creating a Safer Integrating Vector
Erin L. Weber and Paula M. Cannon
Mol Ther 13: S320-S321; doi:10.1016/j.ymthe.2006.08.913
830. Determination of the Profile and Site Preference of Lentiviral Vector Integration In Vivo
Caroline V. Hacker, Conrad V. Vink, Susan M. Kingsman, Kyriacos A. Mitrophanous and James E. Miskin
Mol Ther 13: S321-S321; doi:10.1016/j.ymthe.2006.08.915
831. Apoptosis Induced by Oncolytic M Protein Mutant Vesicular Stomatitis Virus Is Dependent on PKR, Fas, and Daxx
Daniel F. Gaddy and Douglas S. Lyles
Mol Ther 13: S321-S321; doi:10.1016/j.ymthe.2006.08.916
832. Efficient Readministration of Adenovectors to the Inner Ear
Hinrich Staecker, Mark Praetorius, Chi Hsu and Douglas E. Brough
Mol Ther 13: S321-S322; doi:10.1016/j.ymthe.2006.08.918
833. Combined Manganese Superoxide Dismutase Gene Therapy and 5-FU Chemotherapy for Colorectal Cancer
Yanhong Zhang, Lingfeng He, Songqing He, Jian Wu and Xinyuan Liu
Mol Ther 13: S322-S322; doi:10.1016/j.ymthe.2006.08.919
834. Protective Effect of Bcl-XL Gene Expression on the Radiation-Induced Acute Intestinal Injuries
Kazuaki Uchimoto, Fumikazu Koyama, Kazuo Ohashi, Kenichi Ohtsuki, Hirofumi Hamada, Takeo Nomi, Hisao Fujii, Tomohide Mukogawa and Yoshiyuki Nakajima
Mol Ther 13: S322-S322; doi:10.1016/j.ymthe.2006.08.920
835. Inhibition of Hepatic SPARC (Secreted Protein Acidic and Rich in Cysteine) Expression for the Treatment of Experimental Cirrhosis
Alejandra M. Camino, Federico Prada, Osvaldo Podhajcer, Marcelo O. Silva and Guillermo D. Mazzolini
Mol Ther 13: S322-S323; doi:10.1016/j.ymthe.2006.08.921
836. Changes in Maturation Profiles of Dendritic Cells Transduced with a CD40-Targeted Adenoviral Vector
Disha A. Mody, Alexander V. Pereboev, Don A. Sibley, David T. Curiel and J. Michael Mathis
Mol Ther 13: S323-S323; doi:10.1016/j.ymthe.2006.08.922
837. Colon-Directed Delivery of Viral Vectors Using Virus-Microbead Conjugates for Gene Therapy of Inflammatory Bowel Disease
Alan Jerusalmi, Samuel J. Farlow and Takeshi Sano
Mol Ther 13: S323-S324; doi:10.1016/j.ymthe.2006.08.172
838. 10 Year Follow-Up of 146 Advanced Stage NSCLC Patients Who Received Adenoviral Based Therapy
John Nemunaitis, Been Pappen, Rosemarie Arzaga, Casey Cunningham and Neil Senzer
Mol Ther 13: S324-S324; doi:10.1016/j.ymthe.2006.08.924
839. Long-Term Knockdown of Phospholamban in Cultured Neonatal Rat Cardiomyocytes by a Viral Vector Expressing PLB-shRNAs
Lennart Suckau, Jens Kurreck, Roland Vetter, Stefan Weger, Jos Lamers, Wolfgang Poller and Henry Fechner
Mol Ther 13: S324-S324; doi:10.1016/j.ymthe.2006.08.925
840. Markedly Enhanced Cytolysis by E1B-19kD-Deleted Oncolytic Adenovirus in Combination with Cisplatin
A-Rum Yoon, Young-Sook Lee, Ji-Young Yoo, Hoguen Kim, Jinsun Kim, Joong Bae Ahn, Joo-Hang Kim and Chae-Ok Yun
Mol Ther 13: S324-S325; doi:10.1016/j.ymthe.2006.08.926
841. Anti-Tumor Effect of Tumor Specific Replicating Adenovirus Expressing IL-12 and IL-18
Jing-Hua Huang, Il-Kyu Choi, Sung-Mi Jung, Minjung Kim, Joo-Hyuk Sohn, Chae-Ok Yun and Joo-Hang Kim
Mol Ther 13: S325-S325; doi:10.1016/j.ymthe.2006.08.927
842. Novel Oncolytic Adenoviruses for Cancer Gene Therapy
Devanand Sarkar, Zao-zhong Su and Paul B. Fisher
Mol Ther 13: S325-S325; doi:10.1016/j.ymthe.2006.08.928
843. MicroPET Imaging of HSV-TK Activity To Assess Cancer-Specific Gene Expression Targeted at the Level of Protein Translation Initiation
Don A. Sibley, Shayne Barlow, Ricky DeBenedetti, David T. Curiel and J. Michael Mathis
Mol Ther 13: S325-S326; doi:10.1016/j.ymthe.2006.08.929
844. A Single Vector-Dependent, Doxycycline- Regulatable, Lung Cancer Specific Oncolytic Adenovirus
Isaac Sipo, Almudena Hurtado Pico, Judith Wildner, Lennart Suckau, Sandra Pinkert, Stefan Weger, Wolfgang Poller and Henry Fechner
Mol Ther 13: S326-S326; doi:10.1016/j.ymthe.2006.08.930
845. The Loss Expression of Coxsackie and Adenovirus Receptor Enhances the Feature of Aggressive Bladder Cancer
Kazumasa Matsumoto, Sharokh F. Shariat, Akira Irie, Tetsuo Fujita, Hiroshi Okusa, Takefumi Satoh, Masatsugu Iwamura, Shiro Baba and Seth P. Lerner
Mol Ther 13: S326-S326; doi:10.1016/j.ymthe.2006.08.931
846. Enhanced Antitumor Effect of Oncolytic Adenovirus Expressing Interleukin-12 and B7.1 in an Immuneocompetenet Mouse Model
Ji Young Yoo, Young-Sook Lee, Jaesung Kim, Hyejin Choi, Joo-Hang Kim and Chae-Ok Yun
Mol Ther 13: S326-S326; doi:10.1016/j.ymthe.2006.08.932
847. Combined Oncolytic Adenovirus with Double Suicide Gene in Killing Lung Cancer
Ju Feng Zhang and Chen Huang
Mol Ther 13: S327-S327; doi:10.1016/j.ymthe.2006.08.933
848. Helper Dependent Adenovirus-Epstein- Barr Virus Hybrid Vector for Long Term Persistance in Hepatocytes
Jose S. Gil, Sean D. Gallaher and Arnold J. Berk
Mol Ther 13: S327-S327; doi:10.1016/j.ymthe.2006.08.934
849. E1A- and E1B-Double Mutant Replicating Adenovirus Elicits Enhanced Oncolytic and Anti- Tumor Effects
Jinsun Kim, Jaesung Kim, Joo-Hang Kim, Kyung-Ju Choi, Pyung-Hwan Kim and Chae-Ok Yun
Mol Ther 13: S327-S327; doi:10.1016/j.ymthe.2006.08.935
850. Concurrent Delivery of GM-CSF and B7-1 Using an Oncolytic Adenovirus Elicits Potent Anti- Tumor Effect on the Growth Established B16-F10 Tumor Model
Min-Ju Kim, Kyung-Ju Choi, Yoon-A Kang, Oh-Joon Kwon, Pyung-Hwan Kim, Chae-Ok Yun and Joo-Hang Kim
Mol Ther 13: S327-S328; doi:10.1016/j.ymthe.2006.08.936
851. Molecular Determination of High-Capacity Helper Dependent Adenoviral Vector Genomes In Vitro and In Vivo
Mariana Puntel, James F. Curtin, Jeffrey M. Zirger, A.K.M. Muhammad, Xiong Weidong, Chunyan Liu, Jinwei Hu, Kurt M. Kroeger, Peter Czer, Sandra Sciascia, Pedro R. Lowenstein and Maria G. Castro
Mol Ther 13: S328-S328; doi:10.1016/j.ymthe.2006.08.937
852. Chromatin Study of Adenovirus Vector DNA In Vivo
Dan Cao and Mark A. Kay
Mol Ther 13: S328-S328; doi:10.1016/j.ymthe.2006.08.938
853. Monitoring of Promoter-Controlled Adenoviral Replication with Noninvasive Imaging in Lung Cancer
Julia Davydova, Amy R. Nelson, Tatyana Gavrikova, Long P. Le, Hidetaka A. Ono, David T. Curiel and Masato Yamamoto
Mol Ther 13: S328-S328; doi:10.1016/j.ymthe.2006.08.939
854. Potential of the Oncolytic Adenovirus Delo3 RGD in the Treatment of Malignant Carcinoma Cells
Klaus Mantwill, Per S. Holm and Bernd Gansbacher
Mol Ther 13: S329-S329; doi:10.1016/j.ymthe.2006.08.939
855. B-Specific Lentiviral Vectors Expressing Btk: Tools for a Gene Therapy of X-Linked Agammaglobulinemia
Thomas Moreau, Vincent Barlogis, Christian Chabannon and Cecile Tonnelle
Mol Ther 13: S329-S329; doi:10.1016/j.ymthe.2006.08.941
856. Improvements on Safety and Efficacy of Nonviral Gene Therapy of Factor VII for Hemophilia A with Inhibitors
Steven C. Chen, Daniel Greenberg, Peiqing Ye, Earl W. Davie and Carol H. Miao
Mol Ther 13: S329-S330; doi:10.1016/j.ymthe.2006.08.942
857. Molecular Engineering of Factor VIII for rAAV Delivery
Lingxia Chen, Hui Lu, Juan Li, Haiyan Jiang, Rita Sarkar, Glenn Pierce, Rodney Camira, Valder Arruda, Xiao Xiao and Weidong Xiao
Mol Ther 13: S330-S330; doi:10.1016/j.ymthe.2006.08.943
858. In Vivo Engineering of Hepatic Tissues Expressing Factors VIII and IX as a Potential New Therapy toward Hemophilia
Kazuo Ohashi, Takashi Yokoyama, Hiroyuki Kuge, Masayuki Yamato, Akira Yoshioka and Yoshiyuki Nakajima
Mol Ther 13: S330-S330; doi:10.1016/j.ymthe.2006.08.944
859. Cats Produce a CTL Response That Reduces Expression of Human Factor IX and Human Factor VIII after Neonatal Gene Transfer and Represent an Important Model for Translation into Humans
Lingfei Xu, Manxue Mei, Mark E. Haskins, Patty O'Donnell, Karyn Cullen and Katherine P. Ponder
Mol Ther 13: S331-S331; doi:10.1016/j.ymthe.2006.08.945
860. Sustained Long-Term In Vivo Expression of Human Factor IX from Keratinocytes Transduced with HIV-Based Vectors
Angeles Escarti-Nebot, Fernando Serrano, Marcela del Rio, Fernando Larcher and Antonio Bernad
Mol Ther 13: S331-S331; doi:10.1016/j.ymthe.2006.08.946
861. Recombinant Adeno-Associated Virus Vector Mediated Gene Therapy of Adenosine Deaminase Deficiency in a Mouse Model
Jennifer M. Crawford, Teh-sheng Chan and Lillian L. Chan
Mol Ther 13: S331-S332; doi:10.1016/j.ymthe.2006.08.947
862. Feasibility of Cutaneous Gene Therapy Using a Factor VIII Gene and a Marker Gene in Factor VIII-Deficient Mice by Non-Invasive Electroporation
Lei Zhang, Amy Goldbeck, Hongbo Lu, Edward Nolan, Dietmar Rabussay and Steve Fakharzadeh
Mol Ther 13: S332-S332; doi:10.1016/j.ymthe.2006.08.948
863. Liver Gene Therapy for Hemophilia with phiC31 Integrase
Lauren E. Woodard, Annahita Keravala, Robert T. Hillman, Julien Sage and Michele P. Calos
Mol Ther 13: S332-S332; doi:10.1016/j.ymthe.2006.08.949
864. Characterization of Transgenic Mice Over-Expressing Arylsulfatase A: Implications for Gene Therapy and Sulfatases Activation Mechanisms
Alessia Capotondo, Mary A. Venneri, Maria P. Cosma, Isabella Pallavicini, Andrea Ballabio, Luigi Naldini and Alessandra Biffi
Mol Ther 13: S332-S333; doi:10.1016/j.ymthe.2006.08.950
865. In Vivo Gene Transfer of Prostacyclin Synthase by Using AAV Vector Prevents Monocrotaline-Induced Pulmonary Hypertension and Pulmonary Vasoconstriction in Rats
Takayuki Ito, Takashi Okada, Jun Mimuro, Hiroshi Miyashita, Mutsuko Nonaka-Sarukawa, Hiroaki Mizukami, Akihiro Kume, Masafumi Takahashi, Keiji Yamamoto, Kazuyuki Shimada and Keiya Ozawa
Mol Ther 13: S333-S333; doi:10.1016/j.ymthe.2006.08.953
866. Aortic Disease in Mucopolysaccharidodis I Mice Is Due to Increased Expression of Matrix Metalloproteinase 12 (MMP 12) Can Be Prevented with Neonatal Retroviral Vector-Mediated Gene Therapy
Xiucui Ma, Mindy Tittiger, Russ Knutson, Robert Mecham, Laura Schaller and Katherine Ponder
Mol Ther 13: S333-S334; doi:10.1016/j.ymthe.2006.08.954
867. Spliceosome Mediated RNA Trans-Splicing To Increase Blood Levels of Apolipoprotein A-I and High Density Lipoproteins
Madaiah Puttaraju, Jun Wang, Alan T. Remaley, Bryan H. Brewer Jr., Mariano A. Garcia-Blanco and Gerard J. McGarrity
Mol Ther 13: S334-S334; doi:10.1016/j.ymthe.2006.08.955
868. Novel Strategies To Inhibit Ocular Neovascularization Based on Sonic Hedgehog Pathway Blockade
Gabriella Cotugno, Enrico M Suace and Alberto Auricchio
Mol Ther 13: S334-S334; doi:10.1016/j.ymthe.2006.08.956
869. Accelerated Re-Endothelilization in eNOS Transduced Iliac Artery Following Gene Delivery from an Adenoviral Eluting Stent
Faisal Sharif, Sean O. Hynes, James Crowley, Kieran Daly and Timothy O'Brien
Mol Ther 13: S334-S335; doi:10.1016/j.ymthe.2006.08.957
870. NOS Isoforms, Intimal Hyperplasia and Endothelial Regeneration after Balloon Injury
Ronan Cooney, Sean O. Hynes, Sharif Faisal and Timothy O'Brien
Mol Ther 13: S335-S335; doi:10.1016/j.ymthe.2006.08.958
871. Surface Modification of Adenovectors with TAT- and Antp-Containing Polymers Protects Them from Neutralizing Antibodies and Increases Expression of Reporter Genes In Vitro and In Vivo
Ilia Fishbein, Ivan S. Alferiev, Richard Gaster, Meizan Lai and Robert J. Levy
Mol Ther 13: S335-S335; doi:10.1016/j.ymthe.2006.08.959
872. Highly Efficient Virus-Mediated Gene Transfer to Human Vein Grafts Via Intraluminal Pressure Delivery
Oliver Y. Bernecker, Robert Stigler, Severin Semsroth, Guenther Laufer and Johannes Bonatti
Mol Ther 13: S335-S336; doi:10.1016/j.ymthe.2006.08.960
873. Development of High Throughput Functional Screening of Cardiovascular Therapeutic Genes Using the HVJ-E Vector
Tomoyuki Nishikawa, Hironori Nakagami, Atsuhi Matsuki, Yukihiro Saito, Ryuichi Morishita, Katsuto Tamai and Yasufumi Kaneda
Mol Ther 13: S336-S336; doi:10.1016/j.ymthe.2006.08.961
874. Prolonged Adenovirus and Adeno-Associated Virus-Mediated Gene Delivery to Rabbit Iliac Arteries Using Gene-Eluting Stents: A Direct Comparison
Faisal Sharif, Sean Hynes, Jill McMahon, James Crowley and Kieran Daly
Mol Ther 13: S336-S336; doi:10.1016/j.ymthe.2006.08.962
875. Development of Human Skin Gene Therapy for Systemic In Vivo Delivery of Atrial Natriuretic Peptide (ANP) To Treat Hypertension
Jean-Philippe Therrien, Christine L. Tock and Jonathan C. Vogel
Mol Ther 13: S337-S337; doi:10.1016/j.ymthe.2006.08.963
876. Development of Novel Angiogenic DNA Medicine Using a Genomic/cDNA Hybrid of Hepatocyte Growth Factor Gene
Woong Hahn, Dong-Sik Kim, Wook-Bum Pyun, Won-Sun Yoo, Sun-young Kim and Jong-Mook Kim
Mol Ther 13: S337-S337; doi:10.1016/j.ymthe.2006.08.964
877. Differential Expression of Indoleamine 2,3-dioxygenase (IDO) by Endothelial Cells and Its Overexpression by Gene Transfer: Implications for Cardiovascular Biology
Peng H. Tan and Andrew J.T. George
Mol Ther 13: S337-S338; doi:10.1016/j.ymthe.2006.08.965
878. Overexpression of Fibromodulin Inhibits Neointima Formation in Cultured Human Saphenous Veins
Parisa Ranjzad, Husein K. Salem and Paul A. Kingston
Mol Ther 13: S338-S338; doi:10.1016/j.ymthe.2006.08.966
879. Effects of Continuous Expression of Activated Protein C (APC) in Novel Murine Thrombosis Models
Christian Furlan Freguia, Joerg Schuettrumpf, Stefano Baila, Jianhua Liu, Ralph Bunte, Rodney M. Camire and Valder R. Arruda
Mol Ther 13: S338-S338; doi:10.1016/j.ymthe.2006.08.967
880. Towards a Gene Therapy Treatment for Peripheral Vascular Disease |[ndash]| High Level of Expression of Angiogenic Genes in Rat Limb Muscle Following Intravenous Delivery of Plasmid DNAs
Weijun Cheng, Julia O. Hegge, Vladimir Subbotin, Steven Coakley and James E. Hagstrom
Mol Ther 13: S339-S339; doi:10.1016/j.ymthe.2006.08.968
881. Safety, Efficacy and Biodistribution of Recombinant AAV2-RPE65 Vector Delivered by Ocular Subretinal Injection
Samuel G. Jacobson, Gregory M. Acland, Gustavo D. Aguirre, Tomas S. Aleman, Sanford L. Boye, Sharon B. Schwartz, Artur V. Cideciyan, Caroline J. Zeiss, Andras M. Komaromy, Alejandro J. Roman, Elizabeth A.M. Windsor, Alexander Sumaroka, Susan E. Pearce-Kelling, Thomas J. Conlon, Quihong Li, Vincent A. Chiodo, Terence R. Flotte, Albert M. Maguire, Jean Bennett and William W. Hauswirth
Mol Ther 13: S339-S339; doi:10.1016/j.ymthe.2006.08.970
882. Non-Viral Ocular Gene Transfer for Hereditary Retinal Degeneration
Muna I. Naash, Ron M. Ballard, Jeff Skaggs, Zack Nash, Alexander B. Quiambao, Mark J. Cooper and Rafal Farjo
Mol Ther 13: S340-S340; doi:10.1016/j.ymthe.2006.08.971
883. AAV-2 Based Gene Therapy Using Novel Anti-VEGF Molecules for Inhibition of Angiogenesis in the Eye
Abraham Scaria, Peter Pechan, Hillard Rubin, Michael Lukason, Elizabeth Barry, Jeffrey Ardinger, Huawei Qiu, Qiuhong Li, James Peterson, William Hauswirth and Samuel Wadsworth
Mol Ther 13: S340-S340; doi:10.1016/j.ymthe.2006.08.972
884. Anti-Oxidant Gene Delivery to Retinal Epithelial Cells: A Gene Therapy Approach for Macular Degeneration
Lisa McGinley, Gillian Cosgrave, Aoife Duffy, Timothy O'Brien and Padraig M. Strappe
Mol Ther 13: S340-S341; doi:10.1016/j.ymthe.2006.08.973
885. AAV-Mediated Gene Transfer of Constitutively and Pharmacologically-Activated Glial Cell-Derived Neurotrophic Factor Receptor To Inhibit Retinal Degeneration
Mariacarmela Allocca, Umberto Di Vicino, Luciano Domenici, Victor M. Rivera and Alberto Auricchio
Mol Ther 13: S341-S341; doi:10.1016/j.ymthe.2006.08.974
886. AAV-Mediated Somatic Gene Transfer as an Approach To Delineate Pathogenic Mechanisms in an Autosomal Dominant Blindness Disorder Resembling Age-Related Macular Degeneration (AMD)
Nicholas W. Keiser, Arvydas Maminishkis, Jeannette L. Bennicelli, Sheldon S. Miller and Jean Bennett
Mol Ther 13: S341-S341; doi:10.1016/j.ymthe.2006.08.975
887. G Protein-Coupled Receptor Kinase Interacting Protein 1 Slows down the Apoptosis Process of Retinal Ganglion Cells in a Rat Model
Ann-Shung Lieu, Yi Wang, Donna Webb, Gerold R. Hankins, Gergory A. Helm and Jin Zhong Li
Mol Ther 13: S341-S342; doi:10.1016/j.ymthe.2006.08.976
888. Characterization of New Murine Models of Globoid Cell Leukodystrophy: Relevance for Gene Therapy Applications and Studies on Disease Pathogenesis
Ilaria Visigalli, Ubaldo del Carro, Letterio Politi, Angelo Quattrini, Paola Luzi, David Wenger, Luigi Naldini and Alessandra Biffi
Mol Ther 13: S342-S342; doi:10.1016/j.ymthe.2006.08.977
889. Adeno-Associated Virus Gene Therapy of Feline Gangliosidosis
Douglas R. Martin, Begona Cachon-Gonzalez, Miguel Sena-Esteves, Misako Hwang, Atoska S. Gentry, Nancy E. Morrison, Nancy R. Cox, Timothy M. Cox and Henry J. Baker
Mol Ther 13: S342-S342; doi:10.1016/j.ymthe.2006.08.978
890. Improvement of Behavior and Mortality Following CNS Administration of AAVrh.10hCLN2 to CLN2 |[minus]|/|[minus]| Mice, a Model LINCL (Battan Disease) a Fatal Childhood Neurological Disorder (Batten Disease)
Dolan Sondhi, Neil R. Hackett, Daniel A. Peterson, Elizabeth Vassallo, Jamie A. Stratton, Kelly Travis, Timothy P. O'Connor, James M. Wilson and Ronald G. Crystal
Mol Ther 13: S343-S343; doi:10.1016/j.ymthe.2006.08.979
891. Correction of Established Neurologic Disease and Evidences of In Vivo Cross Correction in the Mouse Model of Metachromatic Leukodystrophy
Alessandra Biffi, Alessia Capotondo, Stefania Fasano, Ubaldo del Carro, Sergio Marchesini, Hisaya Azuma, Riccardo Brambilla, Markus Grompe, Claudio Bordignon, Angelo Quattrini and Luigi Naldini
Mol Ther 13: S343-S343; doi:10.1016/j.ymthe.2006.08.980
892. Neural Deficits Contribute to Respiratory Insufficiency in Pompe Disease: A Therapeutic Approach with AAV1
Lara R. DeRuisseau, Cathryn Mah, David D. Fuller and Barry J. Byrne
Mol Ther 13: S344-S344; doi:10.1016/j.ymthe.2006.08.981
893. Second Generation Gene Therapy Vector for Classical Late Infantile Neuronal Ceroid Lipofuscinosis
Mario A. Cabrera-Salazar, Bradley L. Hodges, Nelson S. Yew, Jie Bu, Jonathan A. Fidler, Eric M. Roskelley, Ronald K. Scheule, David E. Sleat, Peter Lobel, Seng H. Cheng and Marco A. Passini
Mol Ther 13: S344-S344; doi:10.1016/j.ymthe.2006.08.982
894. Selective Targeting of GABAergic Neurons Using rAAV: The Potential Role of EAAC1 in Seizure Susceptibility
Melodie L. Weller, Christopher J. Maki, Ida M. Stone and David J. Poulsen
Mol Ther 13: S344-S345; doi:10.1016/j.ymthe.2006.08.983
895. Separate rAAV1 Vectors Co-Infect Striatal Neurons Efficiently
Fredric P. Manfredsson, Aaron C. Rising and Ronald J. Mandel
Mol Ther 13: S345-S345; doi:10.1016/j.ymthe.2006.08.984
896. Long Term Transgene Expression in the Brain Delivered by SV40-Derived Vectors
Jean-Pierre Louboutin, Beverly A.S. Reyes, Lokesh Agrawal, Elisabeth J. van Bockstaele and David S. Strayer
Mol Ther 13: S345-S345; doi:10.1016/j.ymthe.2006.08.985
897. Na,K-ATPase |[beta]|1-Mediated Selective Gene Transfer into Neurons
Keiji Ishii, Kiminori Nakamura, Satoshi Kawaguchi, Rong Li, Sachie Hirai, Naoya Sakuragi, Takuro Wada, Kazunori Kato, Toshihiko Yamashita and Hirofumi Hamada
Mol Ther 13: S346-S346; doi:10.1016/j.ymthe.2006.08.986
898. Intracerebral Exon Skipping Restores Dystrophin Expression in CA1 Pyramidal Neurons of mdx Mice
Elise Peltekian, Karine Ros, Aurelie Goyenvalle, Carole Gruszczynski, Cyrille Vaillend, Serge Laroche, Luis Garcia and Olivier Danos
Mol Ther 13: S346-S346; doi:10.1016/j.ymthe.2006.08.987
899. Utilizing the Vector Transport Properties of AAV-9 as a Method To Get Widespread Distribution of a Therapeutic Gene within the CNS
Cassia N. Cearley and John H. Wolfe
Mol Ther 13: S346-S346; doi:10.1016/j.ymthe.2006.08.988
900. Specific AAV Serotypes Stably Transduce Hippocampal and Cortical Cultures with High Efficiency and Low Toxicity
Nicolas C. Royo, Luk H. Vandenberghe, Julie Johnston, Margaret Maronski, Marc A. Dichter, James M. Wilson and Deborah J. Watson
Mol Ther 13: S347-S347; doi:10.1016/j.ymthe.2006.08.989
901. Targeting of Viral Vectors to Motor Neurons by Botulinum Toxin Binding Domain To Treat ALS
Yang Lu, Robert Adams, Wenji Sun, Iris Lee, Irina Debromilskaya and Daniel B. Drachman
Mol Ther 13: S347-S347; doi:10.1016/j.ymthe.2006.08.990
902. Modulation of Voltage-Gated Potassium Channels in Dorsal Root Ganglion Neurons by an Inducible Adenoviral Vector In Vivo
Chao Ma, Robert H. LaMotte, Jason M. Rosenzweig, Peter L. Gehlbach and David C. Johns
Mol Ther 13: S347-S348; doi:10.1016/j.ymthe.2006.08.991
903. Re-Administration of Recombinant AAV2 and AAV5 in the Brain
Sharon K. Reimsnider, Fredric P. Manfredsson, Corinna Burger, Nicholas Muzczyka and Ronald J. Mandel
Mol Ther 13: S348-S348; doi:10.1016/j.ymthe.2006.08.992
904. The Systemic Human Immune Response to Intraparenchymal Administration of AAV
Scott W.J. McPhee, Chris G. Janson, Chengwen Li, R. Jude Samulski, Angelique S. Camp, Jeremy S. Francis, David Shera, Andrew Freese, Anthony L. Aita, H. Warren Goldman and Paola Leone
Mol Ther 13: S348-S348; doi:10.1016/j.ymthe.2006.08.993
905. The Use of Gene Immunisation To Study the Role of Antibodies to Voltage Gated Potassium Channels in Neuroimmunological Disease
Mary McMenamin, Karen M. McKnight, Matthew J.A. Wood, Bethan Lang, Nikki J. Horwood and Angela C. Vincent
Mol Ther 13: S349-S349; doi:10.1016/j.ymthe.2006.08.994
906. Effective Repetitive Dystrophin Gene Transfer into Skeletal Muscle of Adult mdx Mice Using a Helper-Dependent Adenovirus Vector Expressing the Coxsackievirus and Adenovirus Receptor (CAR) and Dystrophin
Yuji Uchida, Yasushi Maeda, En Kimura and Makoto Uchino
Mol Ther 13: S349-S349; doi:10.1016/j.ymthe.2006.08.996
907. Development of Recombinant Novel Adeno-Associated Viral (rAAV) Vectors Encoding Optimised Microdystrophin cDNAs for Duchenne Muscular Dystrophy (DMD)
Takis Athanasopoulos, Ian Graham, Capucine Trollet, Helen Foster, Norma Perez, Vanessa Hill, Phillippe Moullier and George Dickson
Mol Ther 13: S349-S350; doi:10.1016/j.ymthe.2006.08.997
908. Design and Optimization of U7snRNAs for Skipping of Exon 51 in DMD: Promising Tools for Future Clinical Trials
Aurelie Goyenvalle, Adeline Vulin, Stephanie Lorain, Annemieke Aartsma-Rus, Judith C.T. van Deutekom, Olivier Danos and Luis Garcia
Mol Ther 13: S350-S350; doi:10.1016/j.ymthe.2006.08.998
909. Comparison of Early Stage Healing Responses of Injured Flexor Tendons with Tissue Reactions after Delivery of Adenoviral and Adeno-Associated Viral Vectors to Digital Flexor Tendons
Bei Zhu, Yi Cao, Ke-Qin Xin, Ian C Summerhayes, Xiao Tian Wang, Paul Y. Liu and Jin Bo Tang
Mol Ther 13: S350-S350; doi:10.1016/j.ymthe.2006.08.999
910. Gene Therapy of Glycogenosis Type 2Using SIN-Lentiviral Vectors
Richard Emmanuel, Benhassine Safa, Douillard Gaelle, Batista Lionel and Caillaud Catherine
Mol Ther 13: S350-S351; doi:10.1016/j.ymthe.2006.08.1000
911. C-Terminal Truncated Microdystrophin Recruits Dystrobrevin and Syntrophin to the Dystrophin-Associated Glycoprotein Complex and Reduces Muscular Dystrophy in Symptomatic Utrophin/Dystrophin Double Knock-Out Mice
Yongping Yue, Mingju Liu and Dongsheng Duan
Mol Ther 13: S351-S351; doi:10.1016/j.ymthe.2006.08.1001
912. Accelerated Chondrogenesis in Nanofiber Scaffolds Containing BMP-2 Genetically Engineered Chondrocytes
Robert T. Gorsline, Jin Nam, Prasarn Tangkawattana, John Lannutti and Alicia L. Bertone
Mol Ther 13: S351-S352; doi:10.1016/j.ymthe.2006.08.1002
913. Histone Deacetylase Inhibitors Improve Gene Transfer To Mature Skeletal Muscle
Nancy Larochelle, Jatinderpal R. Deol, Paul Holland, George Karpati and Josephine Nalbantoglu
Mol Ther 13: S352-S352; doi:10.1016/j.ymthe.2006.08.1003
914. Recombinant AAV Gene Delivery of Follistatin for Muscle Enhancement in Models of Muscular Dystrophy
Liza Rizo, Chris Shilling, Amanda Haidet, Priya Umapathi Umapathi, Zarife Sahenk, Jerry R. Mendell and Brian K. Kaspar
Mol Ther 13: S352-S352; doi:10.1016/j.ymthe.2006.08.1004
915. High and Low Affinity Consensus Binding Sequences to Extracellular |[alpha]|7 Integrin X2B Subunit Detected Using Phage Display Biopanning
Daniel P. Reay, Pattarana Sae-chew and Paula R. Clemens
Mol Ther 13: S352-S353; doi:10.1016/j.ymthe.2006.08.1005
916. Genetically Modified Mesenchymal Stem Cells Expressing Transforming Growth Factor-|[beta]|1 Develop a Cartilage Phenotype
Alan J. Nixon, Christina W. Cheng, Lisa Strassheim and Paul D. Robbins
Mol Ther 13: S353-S353; doi:10.1016/j.ymthe.2006.08.1006
917. GM-CSF Gene Transfer to Acute Limb Ischemic Mouse for Limb Recuperation
Mariana Grings, Chester B. Sacramento, Jos|[eacute]| C. Baptista-Silva, Christina M. Takiya, Abram Beutel, Cassia T. Bergamaschi, Ruy R. Campos, Jane Z. Moraes and Sang W. Han
Mol Ther 13: S353-S354; doi:10.1016/j.ymthe.2006.08.1007
918. Rescue of Dystrophin in the GRMD Dog by Multi-Exon Skipping Using Engineered U7 snRNAs
Adeline Vulin, Aurelie Goyenvalle, Ines Barthelemy, France Leturcq, Jean-Claude Kaplan, Olivier Danos, Stephane Blot and Luis Garcia
Mol Ther 13: S354-S354; doi:10.1016/j.ymthe.2006.08.1008
919. Gene Therapy for Duchenne Muscular Dystrophy Using a Gutted Adenovirus Expressing Utrophin
Jatinderpal R. Deol, Renald Gilbert, Gawiyou Danialou, Mylene Bourget, Joon-Shik Moon, Basil J. Petrof, Josephine Nalbantoglu and George Karpati
Mol Ther 13: S354-S355; doi:10.1016/j.ymthe.2006.08.1009
920. Bone Regeneration with Xenogeneic BMP-2 Producing Fibroblasts
Moon Jong Noh, Chae-Lyul Lim, Jong-pil Hyun, Hyeon-youl Lee, Kyoung Baek Choi, Youngsuk Yi and Kwan Hee Lee
Mol Ther 13: S355-S355; doi:10.1016/j.ymthe.2006.08.1010
921. In Vivo Non Viral Gene Delivery of BMP-9 Regenerates Non Union Bone Defect
Nadav Kimelman, Gadi Pelled, Yoram Zilberman, Evellin Zeira, Hagit Yotvat, Eitan Galun, Jinzhong Li, Gregory A. Helm and Dan Gazit
Mol Ther 13: S355-S356; doi:10.1016/j.ymthe.2006.08.1011
922. Improvement of Anti-Tumor Activity by Gene Amplification with a Replicative, Non-Disseminative Adenovirus
Cara J. Lau, Denis Bourbeau, Jairo Jaime, Josephine Nalbantoglu and Bernard Massie
Mol Ther 13: S356-S357; doi:10.1016/j.ymthe.2006.08.1013
923. Combining In Situ Gene Therapy with Radiotherapy and Hormonal Therapy in the Treatment of Stage D1 Prostate Cancer
Tetsuo Fujita, Bin S. Teh, Terry L. Timme, Gustavo Ayala, Wei-Yuan Mai, Takefumi Satoh, Nobuyuki Kusaka, Koji Naruishi, Ken-ichi Tabata, Estuardo Aguilar-Cordova, Thomas Wheeler, E. Brian Butler and Timothy C. Thompson
Mol Ther 13: S356-S357; doi:10.1016/j.ymthe.2006.08.1014
924. D-MAPP Analogue, LCL-204 Sensitizes DU145 Prostate Cancer Cells (PCa) to FasL Gene Therapy through Down-Regulation of Survivin
Ahmed M. El-Zawahry, Xiang Liu, Saeed ElOjeimy, David Holma, Ayman Elmahdy, Nabil K. Bissada, Hashim M. Rashwan, Zdzislaw Szulc, Alicjia Bielwaska, Jasek Bielwaski, Thomas Keane, Yusuf Hannun and James Norris
Mol Ther 13: S357-S357; doi:10.1016/j.ymthe.2006.08.1015
925. Novel Fusion Enzymes of Herpes Simplex Virus Thymidine Kinase Mutants and Guanylate Kinase for Improved Cancer Cell Ablation
Andressa Ardiani, Candice Willmon, Elizabeth Krabbenhoft and Margaret E. Black
Mol Ther 13: S357-S357; doi:10.1016/j.ymthe.2006.08.1016
926. The Combination of P19ARF-HIV Tat Cytotoxic Gene Expression with AAT-1 PDX Increases Cell Killing of Brain Tumor Cells
Wouter J. Driessen and Sean M. Sullivan
Mol Ther 13: S357-S358; doi:10.1016/j.ymthe.2006.08.1017
927. Development of Non-Viral Gene Therapy Targeting Insulin-Like Growth Factor (IGF) System for Treatment of Brain Tumors
Leah R. Villegas, Sean Sullivan and Maria Grant
Mol Ther 13: S358-S358; doi:10.1016/j.ymthe.2006.08.1018
928. Reversal of PPC1 Prostate Cancer Cells Radioresistance by Degradation of Acid Ceramidase Using the Lysosomotropic Drug LCL385
Ayman E.M. Mahdy, Xiang Liu, Saeed N. ELojeimy, Alicja Bielaswka, Yusuf A. Hannun, Thomas E. Keanne, Ahmed M. El-Zawahry and James S. Norris
Mol Ther 13: S358-S359; doi:10.1016/j.ymthe.2006.08.1019
929. Functional Potential of Human T Cells Following Lentiviral Suicide Gene Transduction
Taylor Mackey, Joanne Buddle, Christine Kinnon, Adrian Thrasher, Hubert Gaspar and Waseem Qasim
Mol Ther 13: S359-S359; doi:10.1016/j.ymthe.2006.08.1020
930. Engineering Human Deoxycytidine Kinase for Improved Prodrug Sensitivity for Cancer Gene Therapy
Candice L. Willmon and Margaret E. Black
Mol Ther 13: S359-S359; doi:10.1016/j.ymthe.2006.08.1021
931. Inhibition of VEGF Signaling Pathway and Tumor Metastasis
Yi Lu and Jun Zhang
Mol Ther 13: S359-S360; doi:10.1016/j.ymthe.2006.08.1022
932. Combined Treatment with Tarceva, an EGFR Inhibitor with Ad-mda7 Synergizes To Promote Anti-Tumor Activity Against Human Cancer Cells
Rajagopal Ramesh, Satoshi Inoue and Sunil Chada
Mol Ther 13: S360-S360; doi:10.1016/j.ymthe.2006.08.1023
933. Adenovirus-Mediated Delivery of Secretable Trimeric TRAIL Enhances Apoptosis and Improves Survival Compared with Conventional Chemotherapy for Malignant Gliomas
Moonsup Jeong, In-Ho Kwon, Yong-Sam Kwon, Min-Tae Park, Chae-Young Kim, Sue-Hyung Kang, Kang-Won Song, Yong Ko, Dai-Wu Seol, Paul D. Robbins and Byong-Moon Kim
Mol Ther 13: S360-S360; doi:10.1016/j.ymthe.2006.08.1024
934. Gene Therapy for Colon Cancer by Adeno-Associated Viral Vector-Mediated Transfer of Apolipoprotein(a) Kringles
Kyuhyun Lee, Seong-Tae Yun, Hong-Kyu Lee and Eui-Cheol Jo
Mol Ther 13: S361-S361; doi:10.1016/j.ymthe.2006.08.1025
935. Anti-PI3K/Akt Cell Survival Pathway Gene Therapy Supplemented with Plant Sterol Diet for Prostate Cancer Treatment
Jun Zhang and Yi Lu
Mol Ther 13: S361-S361; doi:10.1016/j.ymthe.2006.08.1026
936. Novel Oncolytic HSV-1 Mutant Expressing ICP 34.5 under the Transcriptional Control of Musashi1 Promoter for the Treatment of Gliomas
Takahito Yazaki, Ryuichi Kanai, Hideyuki Okano and Takeshi Kawase
Mol Ther 13: S361-S361; doi:10.1016/j.ymthe.2006.08.1027
937. Radioprotection of Normal Tissue Cells by Transfer of the Human Superoxide-Dismutase Gene
Marlon R. Veldwijk, Carsten Herskind, Stephanie Laufs, W. Jens Zeller, Stefan Fruehauf and Frederik Wenz
Mol Ther 13: S362-S362; doi:10.1016/j.ymthe.2006.08.1028
938. Ceramide May Have a Role in Sensitizing ACHN Renal Cancer Cells (RCC) to Fas Induced Apoptosis
Ahmed M. El-Zawahry, David Holman, Xiang Liu, Saeed ElOjeimy, Sunil Sudarshan, Nabil K. Bissada, Hashim Rashwan, Zdzislaw Szulc, Alicjia Bielwaska, Thomas Keane, Yusuf Hannun and James Norris
Mol Ther 13: S362-S362; doi:10.1016/j.ymthe.2006.08.1029
939. Adenovirus-Mediated TA-p73|[beta]| Gene Transfer Leads to Chemosensitization of Human Malignant Melanoma
Sebastian Tuve, Tomas Racek, Annett Niemetz, Julia Schultz, Maria S. Soengas and Brigitte M. P|[uuml]|tzer
Mol Ther 13: S362-S362; doi:10.1016/j.ymthe.2006.08.1030
940. Chemotherapeutic Agent DFMO as an Intensifier of Suicide Gene Therapy
Tiina Wahlfors, Tanja Hakkarainen, Juhani J|[auml]|nne, Leena Alhonen and Jarmo Wahlfors
Mol Ther 13: S363-S363; doi:10.1016/j.ymthe.2006.08.1031
941. Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Transgenic Effects on Irradiation-Induced Reactive Oxygen Species (ROS) in Normal Tissue Also Destabilize Antioxidant Pools in Orthotopic Oral Cavity Tumors
Michael W. Epperly, Suhua Nie, Anthony J. Kanai and Joel S. Greenberger
Mol Ther 13: S363-S363; doi:10.1016/j.ymthe.2006.08.1032
942. Adenoviral Mediated Re-Expression of Wnt Antagonist Dkk-1 Induces Apoptosis and Suppresses Tumor Growth in Medulloblastoma
Rajeev Vibhakar, Beverly L. Davidson and Anup Madan
Mol Ther 13: S363-S363; doi:10.1016/j.ymthe.2006.08.1033
943. Prognostic Determinants Associated with Efficacy of Adenoviral p53 Gene Therapy in Patients with Recurrent Squamous Cell Carcinoma of the Head and Neck
John Nemunaitis, Carol Bier-Laning, Gary L. Clayman, David Van Echo, L. Guertin, J. Hamm, Robert Dreicer, George H. Yoo, H. Minn, M. Bekradda, W. Sutherland, Kerstin B. Menander, Robert E. Sobol and Jerry Goodwin
Mol Ther 13: S364-S364; doi:10.1016/j.ymthe.2006.08.1034
944. Inhibiting Survivin Expression Enhances Trail-Induced Apoptosis in Human Hepatocellular Carcinoma
Song-Qing He, Ming-Guang Gong, Zhi-Yong Huang, Chang-Hai Li, Wan-Guang Zhang, Jian Wu and Xiao-Ping Chen
Mol Ther 13: S364-S365; doi:10.1016/j.ymthe.2006.08.1035
945. Combination Treatment of Adenovirus Mediated HSV-Thymidine Kinase Suicide Gene Therapy and Docetaxel in Bladder Cancer
Hideyuki Yamashita, Weiguo Jian, April Gillbert and Seth P. Lerner
Mol Ther 13: S365-S365; doi:10.1016/j.ymthe.2006.08.1036
946. Effect of Androgen Receptor Suppression Using Dominant Negative Inhibition on Castration-Resistant Prostate Cancer
Brian J. Zeithaml, Mark Titus, Karin Haack, Adam Cockrell, Angela Ponguta, Elizabeth Wilson, James Mohler and Tal Kafri
Mol Ther 13: S365-S365; doi:10.1016/j.ymthe.2006.08.1037
947. Gene Directed Enzyme/Prodrug Therapy of Human Glioma Xenografts Using Mutant Escherichia coli Cytosine Deaminase
Sergey A. Kaliberov, Valentina Krendelchtchikova, Debbie Della Manna, Jeffrey C. Sellers, Lyudmila N. Kaliberova, Margaret E. Black and Donald J. Buchsbaum
Mol Ther 13: S365-S366; doi:10.1016/j.ymthe.2006.08.1038
948. Rapid Production of Specific Artificial Meganucleases for Gene Correction in Patients with Inherited Disease
Philippe Duchateau, Patrick Chames, Jean-Charles Epinat, Arnould Sylvain, Julie Smith, Agnes Gouble, Christophe Perez, Sylvestre Grizot and Frederic Paques
Mol Ther 13: S366-S366; doi:10.1016/j.ymthe.2006.08.1040
949. Oncolytic Autonomous Parvovirus (rH1-yCD) Targeting with P4/Carcinoembryonic Antigen Chimeric Promoter for Virotherapy of Pancreatic Cancer
Soukaina Rejiba, Marc Aprahamian and Amor Hajri
Mol Ther 13: S366-S366; doi:10.1016/j.ymthe.2006.08.1041
950. |[beta]|hCG Expressing CRAd for Prostate Cancer
Maria Rajecki, Lotta Kangasniemi, Mikko Tenhunen, Anna Kanerva, Renee A. Desmond, Ulf-Hakan Stenman, Martti Y. Ala-Opas and Akseli Hemminki
Mol Ther 13: S366-S367; doi:10.1016/j.ymthe.2006.08.1042
951. A New Vector Based on Baculovirus Was Effective in Inhibiting Glioma Cell Growth in the Rat Brain
Chaoyang Wang and Shu Wang
Mol Ther 13: S367-S367; doi:10.1016/j.ymthe.2006.08.1043
952. Human Mesenchymal Stem Cells Migrate to Colon Cancer Xenografts: Potential Carriers of Cancer Therapeutics
Steven P. Zielske and Theodore S. Lawrence
Mol Ther 13: S367-S367; doi:10.1016/j.ymthe.2006.08.1044
953. Therapeutic Ultrasound Mediated Anti- Angiogenic Gene Delivery Results with Prostate Tumors Inhibition
Maayan Duvshani-Eshet and Marcelle Machluf
Mol Ther 13: S367-S368; doi:10.1016/j.ymthe.2006.08.1045
954. High Intensity Focused Ultrasound (HIFU) Induced Trans-Gene Activation in Solid Tumors
Yunbo Liu, Zhenlin Hu, Xiaochun Lu, Takashi Kon, Chuanyuan Li and Pei Zhong
Mol Ther 13: S368-S368; doi:10.1016/j.ymthe.2006.08.1046
955. Transduction Efficiency Screening for 7 Different AAV Serotypes in 12 Human Cancer Cell Lines and 2 Xenograft Animal Models
Keerang Park, Youn-Ju Kim, Dong Kyu Kim, Young-Hwa Cho, Jong-Koo Kang, Seock-Yeon Hwang, Hee-Jong Kim, Jin-Hyun Lee, Sung-Ha Cho, So-Yong Yi, Sun-Kyoung Kim and Eun-Jung Park
Mol Ther 13: S368-S368; doi:10.1016/j.ymthe.2006.08.1047
956. Imaging of Radiation-Inducible Promoters Using a Naturally Secreted Luciferase from the Marine Copepod Gaussia princeps
Christian E. Badr, Pierre Zalloua, Xandra O. Breakefield and Bakhos A. Tannous
Mol Ther 13: S369-S369; doi:10.1016/j.ymthe.2006.08.1048
957. Effect of Ligand Binding Affinity and Receptor Density in Relation to Biology of Retargeted Viruses
Kosei Hasegawa, Takafumi Nakamura, James D. Marks, Stephen J. Russell and Kah-Whye Peng
Mol Ther 13: S369-S369; doi:10.1016/j.ymthe.2006.08.1049
958. Sleeping Beauty-Mediated Gene Therapy for Colorectal Cancer
Lalitha R. Belur, Tavanna Buske, Brent Sorensen, Kelly Podetz-Peterson, Daniel Saltzman, Perry B. Hackett and R. Scott McIvor
Mol Ther 13: S369-S369; doi:10.1016/j.ymthe.2006.08.1050
959. Tumor Therapy Via Vector-Regulated Expression of Mutant Sodium Channel
Bakhos A. Tannous, Katherine F. Perry, Miguel Sena-Esteves, Jaime Garcias-Anoveros, Andreas Jacobs, David P. Corey, Ralph Weissleder and Xandra O. Breakefield
Mol Ther 13: S370-S370; doi:10.1016/j.ymthe.2006.08.1051
960. Forced Expression of the Heat Shock Protein H11 Causes Growth Arrest and Apoptosis of Melanoma Cells through TAK1 Activation and Inhibits Tumor Growth in Xenograft Models
Baiquan Li, Cynthia C. Smith, Jennifer M. Laing and Laure Aurelian
Mol Ther 13: S370-S370; doi:10.1016/j.ymthe.2006.08.1052
961. Angiopoietin-1 Enhances the Effect of Paclitaxel on Breast Cancer Cell Killing in a Mouse Model
YaoQi Huang, Harald Sauthoff, Jin Cheng, David Kutler, Sheila Heitner, William N. Rom and John G. Hay
Mol Ther 13: S370-S370; doi:10.1016/j.ymthe.2006.08.1053
962. The Ras/Raf-1/MEK/ERK Signaling Pathway Dictates Host Cell Permissiveness to VSV Infection
Josh A. Noser, Ryuta Sakuma, Patrick W.K. Lee and Yasuhiro Ikeda
Mol Ther 13: S371-S371; doi:10.1016/j.ymthe.2006.08.1054
963. MITF as a Potential Molecular Target for Gene Therapy for Human Melanoma; a Synergistic Inhibitory Effect of Inactivation of Both MITF and BRAFV600E on Melanoma Growth
Kenji Kido, Hidetoshi Sumimoto, Sakiyo Asada, Starlyn Okada, Toshiaki Saida and Yutaka Kawakami
Mol Ther 13: S371-S371; doi:10.1016/j.ymthe.2006.08.1055
964. Combinatorial Process for Engineering Specific Meganucleases with Tailored Specificities toward a Natural Target in the XPC Gene
Christophe Perez, Sylvain Arnould, Julie Smith, Sylvestre Grizot, Agnes Gouble, Philippe Duchateau and Frederic Paques
Mol Ther 13: S371-S371; doi:10.1016/j.ymthe.2006.08.1056
965. Lymphatic and Systemic Metastasis of Prostate Cancer Induced by VEGF-C
Jeremy B. Burton, Ebba Brakenhielm, Saul J. Priceman, Nelson Chavarria, Kari Alitalo and Lily Wu
Mol Ther 13: S372-S372; doi:10.1016/j.ymthe.2006.08.1057
967. Targeted Delivery of Antisense Oligonucleotides to Human T-Leukemia Cells Mediated by Novel Liposomal Formulations: Evaluation of In Vitro and In Vivo Anti-Tumoral Activity
Cristina Fonseca, Liliana Mendon|[ccedil]|a, Jo|[atilde]|o Nuno Moreira, Ant|[oacute]|nio Cabrita, Artur Paiva, Maria Teresa Lopes, Maria C. Pedroso de lima and S|[eacute]|rgio Sim|[otilde]|es
Mol Ther 13: S372-S372; doi:10.1016/j.ymthe.2006.08.1059
968. Next Generation Measles Virus Vectors for Oncolytic Therapy: Targeted, Armed and Stealth
Guy Ungerechts, Christoph Springfeld, Adele Fielding and Roberto Cattaneo
Mol Ther 13: S373-S373; doi:10.1016/j.ymthe.2006.08.1060
969. Bone Marrow Derived Endothelial Progenitor Cells Engineered by Lentiviral Vectors as Therapeutic Antitumoral Strategy
Veronica Fernandez, Milosz Kawa, Guanhua Yang, Jesus Prieto and Cheng Qian
Mol Ther 13: S373-S373; doi:10.1016/j.ymthe.2006.08.1061
970. Transcriptional Activation of krox-1 Induced by Sexual Hormones in Osteosarcoma Cells
Francisco Martinez-F, Fausto A. Jimenez-O, Catalina Machuca-R, Hilda Villegas-C and Kathleen Sakamoto
Mol Ther 13: S373-S374; doi:10.1016/j.ymthe.2006.08.1062
971. Novel Ribozyme-Based Strategy for Cancer Chemoprevention
Suparna Mukhopadhyay, Wolfgang Zacharias and William G. McGregor
Mol Ther 13: S374-S374; doi:10.1016/j.ymthe.2006.08.1063
972. Inhibition of TGF-|[beta]| by RNA Interference To Modulate Breast Cancer Metastasis
Lakisha D. Moore and Selvarangan Pponnazhagan
Mol Ther 13: S374-S374; doi:10.1016/j.ymthe.2006.08.1064
973. SEquence-Enabled Reassembly of |[beta]|-Lactamase (SEER-LAC): A Sensitive Method for the Detection of Double-Stranded DNA
Aik T. Ooi, Cliff I. Stains, Indraneel Ghosh and David J. Segal
Mol Ther 13: S374-S374; doi:10.1016/j.ymthe.2006.08.1065
974. Constitutive Expression of a Mutated Form of CTLA4Ig after Gene Transfer Is Well Tolerated and Prevents Immune Responses Against an Immunogenic Transgene in Nonhuman Primates
Alice Toromanoff, Marcelo Hill, Yan Cherel, Jack-Yves Deschamps, Olivier Gauthier, Bernard Vanhove, Fabienne Rolling, Philippe Moullier, Ignacio Anegon and Caroline Le Guiner
Mol Ther 13: S375-S375; doi:10.1016/j.ymthe.2006.08.1067
975. TLR9 Activation Is Involved in the Immune Response to Helper Dependent Adenoviral Vectors
Vincenzo Cerullo, Michael P. Seiler, Nicola Brunetti-Pierri, Viraje Mane, Christopher Clarcke and Brendan Lee
Mol Ther 13: S375-S375; doi:10.1016/j.ymthe.2006.08.1068
976. TLR and MyD88 Signaling Mediates Innate Immune Responses to Adenoviral Vectors in Mouse
Zhe Zhang, Gaung-Ping Gao, Lee M. Wetzler, Peter L. Bell, Di Wu, Jianping Lin, and James M. Wilson
Mol Ther 13: S375-S376; doi:10.1016/j.ymthe.2006.08.1069
977. Differential Host T Cell Response to the Capsid of AAV2 and 8 in Muscle-Directed Gene Transfer in Murine and Non-Human Primate Models
Lili Wang, Roberto Calcedo, Rebecca Grant, Joanita M. Figueredo and James M. Wilson
Mol Ther 13: S376-S376; doi:10.1016/j.ymthe.2006.08.1070
978. Reduced Immune Response to Adenovirus Vector Formulated with the Anti-Inflammatory Liposome DS/DOPE
Amber Price, Maria Limberis, James M. Wilson and Scott L. Diamond
Mol Ther 13: S376-S376; doi:10.1016/j.ymthe.2006.08.1071
979. Clonal Expansion of a CD8+ T Cell Clone after Retroviral Transduction of Mature T Lymphocytes with the IL-15 Gene
Cary Hsu, Steven A. Rosenberg and Richard A. Morgan
Mol Ther 13: S376-S377; doi:10.1016/j.ymthe.2006.08.1072
980. In Vivo, High Throughput Analysis Expands the Known Anti-Ad Innate Immune Response Profile, and Implicates TLR Pathways in Ad Cellular Immune Response
Zachary Hartman, Anne Kiang and Andrea Amalfitano
Mol Ther 13: S377-S377; doi:10.1016/j.ymthe.2006.08.1073
981. Prevention of Transgene Expression in Antigen Presenting Cells Correlate with Modulated Immune Response after In Vivo Gene Transfer
Andrea Annoni, Brian Brown, Manuela Battaglia, Angelo Lombardo, Luigi Naldini and Maria Grazia Roncarolo
Mol Ther 13: S377-S378; doi:10.1016/j.ymthe.2006.08.1074
982. Adaptive Immune System Down-Regulates Transgene Expression from Adenovirally Infected Neurons in the Brain In Vivo
Jeffrey M. Zirger, Carlos Barcia, Josee Bergeron, Chunyan Lui, Maria G. Castro and Pedro R. Lowenstein
Mol Ther 13: S378-S378; doi:10.1016/j.ymthe.2006.08.1075
983. Repeat Intra-Articular Administration of AAV2 Vectors to Rat Joints
Haim Burstein, Kurt Lustig and Ziv Sandalon
Mol Ther 13: S378-S378; doi:10.1016/j.ymthe.2006.08.1076
984. Liver Restricted Expression of Canine Iduronidase Does Not Prevent a CTL Response in Adult MPS I Mice after Retroviral Vector-Mediated Gene Therapy, but Transient Immunomodulation with CTLA4-Ig Combined with Anti-CD4 or Anti-CD40 Ligand Does
Xiucui Ma, Ramin Herati, Yuli Liu, Anne K. Hennig, Attila Kovacs and Katherine P. Ponder
Mol Ther 13: S378-S379; doi:10.1016/j.ymthe.2006.08.1077
985. Efficient Induction of Tolerance To FIX by Direct Intramuscular Delivery of AAV1
Ellen F. Cohn, Jiacai Zhuo, Meagan Kelly, Jiayin Zhang and Hengjun Chao
Mol Ther 13: S379-S379; doi:10.1016/j.ymthe.2006.08.1078
986. Targeting Transgene Expression to Suprabasal Layers of Epidermis as a Strategy To Evade Immune Responses
Assefa Wondimu, Zhenmei Lu and Soosan Ghazizadeh
Mol Ther 13: S379-S379; doi:10.1016/j.ymthe.2006.08.1079
Abstracts
987. A Cautionary Tale for Immunotherapy Using Genetically Modified Dendritic Cells; Implications for the Future Design of Vaccines
Peng H. Tan and GeorgeJ.T. George
Mol Ther 13: S380-S380; doi:10.1016/j.ymthe.2006.08.1080
988. Repeat Administration of Lentiviral Vector to Mouse Nasal Epithelia
Patrick L. Sinn and Paul B. McCray Jr.
Mol Ther 13: S380-S380; doi:10.1016/j.ymthe.2006.08.1081
989. Induction of Antitumor Immunity by Cell-Penetrating Peptide-Coupled Hsp70 Gene Transfer to Tumor Cells
Takayuki Otsuki, Makiya Nishikawa, Atsushi Ota, Seiji Takemoto and Yoshinobu Takakura
Mol Ther 13: S380-S381; doi:10.1016/j.ymthe.2006.08.1082
990. In Vivo Analysis of Adenovirus Specific Cytotoxic T Lymphocyte Response in CD28, PD-1, Fas Ligand or Perforin Deficient Mice
Jian Chen, Qi Wu, Allan J. Zajac, PingAr Yang, Xin Xu, Hui-Chen Hsu, David T. Curiel and John D. Mountz
Mol Ther 13: S381-S381; doi:10.1016/j.ymthe.2006.08.1083
991. Suppression of Established Collagen Induced Arthritis and Delayed Type Hypersensitivity by Immunosuppressive Dendritic Cell-Derived Exosomes
Seon-Hee Kim, Nicole R. Bianco, William J. Shufesky, Adrian E. Morelli and Paul D. Robbins
Mol Ther 13: S381-S382; doi:10.1016/j.ymthe.2006.08.1084
992. Induction of Immune Tolerance to Transgene Products by Mixed Chimerism with Low Dose Irradiation
Satoru Otsuru, Katsuto Tamai, Takehiko Yamazaki, Takenao Chino, Hideki Yoshikawa and Yasufumi Kaneda
Mol Ther 13: S382-S382; doi:10.1016/j.ymthe.2006.08.1085
993. Optical Bioluminescence and Immunologic Analyses of Lentiviral Vectors Administered In Vivo: Transcriptional Targeting through an MHCII Promoter Yields Persistent Transgene Expression and Lack of CTL Stimulation in Immunocompetent Mice Indicating Tolerance
Takahiro Kimura, Wang Hejing, Richard Koya, Emmanuelle Faure-Kumar, Robert Prins, Begonya Comin-Anduix, Yan Cui, Noriyuki Kasahara and Renata Stripecke
Mol Ther 13: S382-S382; doi:10.1016/j.ymthe.2006.08.1086
994. Effect of Vectors on Human Endothelial Cell Signal Transduction: Implications for Cardiovascular Gene Therapy
Peng H. Tan and George J.T. George
Mol Ther 13: S383-S383; doi:10.1016/j.ymthe.2006.08.1087
995. Effect of Viral Dose on Neutralizing Antibody Response and Transgene Expression after AAV1 Vector Re-Administration in Mice
Harald Petry, Ann Orme, Perry Liu, Maxine Bauzone, Heather Gibson, HuShen Qian, Gabor M. Rubanyi and Richard N. Harkins
Mol Ther 13: S383-S383; doi:10.1016/j.ymthe.2006.08.1088
996. Direct Comparison of Adeno-Associated Virus (AAV) Serotypes for Muscle Expression of Soluble Anti-Angiogenic Proteins
Mayu Isotani, Koichi Miyake, Noriko Miyake, Yukihiko Hirai and Takashi Shimada
Mol Ther 13: S384-S384; doi:10.1016/j.ymthe.2006.08.1089
997. Immune-Mediated Loss of Transgene Expression in Mouse Liver Following Transposon Delivery
Elena L. Aronnovich, Jason B. Bell, Roland Gunther, Brenda Koniar, Aric Frantz, Ilze Matise, R. Scott McIvor, Chester B. Whitley and Perry B. Hackett
Mol Ther 13: S384-S384; doi:10.1016/j.ymthe.2006.08.1090
998. A Comparative Analysis of Transgene-Specific Immune Responses Following In Vivo and Ex Vivo Approaches to Gene Therapy
Zhenmei Lu and Soosan Ghazizadeh
Mol Ther 13: S384-S385; doi:10.1016/j.ymthe.2006.08.1091
999. Mature Effector Immunological Synapses Forming SMAC Mediate Clearance of Virally Infected Astrocytes from the Brain In Vivo
Carlos Barcia, Clare Thomas, James F. Curtin, Gwendalyn D. King, Kolja Wawrowsky, Marianela Candolfi, Wei-Dong Xiong, Liu Chunyan, Kurt Kroeger, Olivier Boyer, Jerzy Kupiec-Weglinski, David Klatzmann, Maria G. Castro and Pedro R. Lowenstein
Mol Ther 13: S385-S385; doi:10.1016/j.ymthe.2006.08.1092
1000. Down-Regulating the Epithelial Glycoprotein-2 Promoter Utilizing Engineered Zinc Finger Protein Transcription Factors
Willemijn M. Gommans, Pamela M.J. McLaughlin, Robbert Cool, Beatrice I. Lindhout, Bert van der Zaal, Hidde J. Haisma and Marianne G. Rots
Mol Ther 13: S385-S385; doi:10.1016/j.ymthe.2006.08.1094
1001. Metabolic Biotinylation of Cell Surface Receptors for In Vivo Imaging
Bakhos A. Tannous, Jan Grimm, Katherine F. Perry, John W. Chen, Weissleder Ralph and Breakefield O. Xandra
Mol Ther 13: S386-S386; doi:10.1016/j.ymthe.2006.08.1095
1002. L1 Cell Adhesion Molecule, a Novel Target of Prostate Cancer Gene Therapy
Kristen Bisanz, Jie Yu, Ira Rajbhandari, Bill Spohn, Mien-Chie Hung, Leland W.K. Chung and Chia-Ling Hsieh
Mol Ther 13: S386-S386; doi:10.1016/j.ymthe.2006.08.1096
1003. Targeted Site-Specific Integration in Human Cells Using Designed Zinc Finger Nucleases
Fyodor D. Urnov, Angelo Lombardo, Jeremy Rock, Erica Moehle, Jeffrey C. Miller, Ya-Li Lee, Philip D. Gregory, Luigi Naldini and Michael C. Holmes
Mol Ther 13: S386-S387; doi:10.1016/j.ymthe.2006.08.1097
1004. c-Jun NH2-Terminal Kinase (JNK)1 and JNK2 Have Distinct Roles in Adenovirus-Mediated Transgene Expression
Fuminori Teraishi, Bingliang Fang, Annin Liu, Futoshi Uno, Shunsuke Kagawa, Toshiyoshi Fujiwara and Noriaki Tanaka
Mol Ther 13: S387-S387; doi:10.1016/j.ymthe.2006.08.1098
1005. Expression of Porcine |[alpha]|(1-3)galactosyltransferase in Non-Human Primate Hematopoietic Progenitors Following Simian Immunodeficiency Virus Mediated Gene Transfer
Lorenzo Benatuil and John Iacomini
Mol Ther 13: S387-S387; doi:10.1016/j.ymthe.2006.08.1099
1006. Effect on Expression of Including Binding Sites for the ELAV-Like Proteins HuD and HuR in Transgene Cassettes
Changyu Zheng and Bruce J. Baum
Mol Ther 13: S387-S388; doi:10.1016/j.ymthe.2006.08.1100
1007. Development of Nuclear Targeting System of Plasmid DNA; Impact of Sugar Display on the Surface of Lipid Envelope
Tomoya Masuda, Hidetaka Akita, Takashi Nishio, Kenichi Niikura, Asako Kudo, Kentaro Kogure, Akitada Iwasa, Kuniharu Ijiro and Hideyoshi Harashima
Mol Ther 13: S388-S388; doi:10.1016/j.ymthe.2006.08.1101
1008. Characterization of Peripheral Regulatory T Cell Phenotype Generated in Molecular Chimeras by Gene Therapy
Jesus R. Paez-Cortez, Chaorui Tian and John Iacomini
Mol Ther 13: S388-S389; doi:10.1016/j.ymthe.2006.08.1102
1009. High Expression of Foxp3 mRNA in Rat Dendritic Cells (DCs) Generated from a Long-Term Culture of Bone Marrow Cells (BMC)
Naoko Fuji (Funeshima), Atsushi Tsuji, Li Xaio-Kang and Hiromitsu Kimura
Mol Ther 13: S389-S389; doi:10.1016/j.ymthe.2006.08.1103
1010. Developing a Potential Pain Therapy Using Engineered Zinc Finger Protein Repressors of the Sodium Channel PN3
Siyuan Tan, Mohammad M. Doroudchi, Xiaohong Zhong, Julie Qiao, Steve Zhang and Philip D. Gregory
Mol Ther 13: S389-S389; doi:10.1016/j.ymthe.2006.08.1104
1011. Growth Factor Receptors as Regulators of Hematopoiesis
Michael A. Weinreich, Ingrid Lintmaer, Linlin Wang, H. Denny Liggitt, Michael A. Harkey and C. Anthony Blau
Mol Ther 13: S389-S389; doi:10.1016/j.ymthe.2006.08.1105
1012. Immortalization of Murine Hematopoietic Stem and Progenitor Cells by AML1-ETO and HoxB4
Michaela Scherr, Gernot Beutel, Karin Battmer, Letizia Venturini, Daniel Schaefer, Arnold Ganser and Matthias Eder
Mol Ther 13: S389-S390; doi:10.1016/j.ymthe.2006.08.1106
1013. Comparison of VP22 Intercellular Spreading in Live Versus Fixed Cells
Ulrich M. Lauer, Marie-Luise Lemken, Wolfgang A. Wybranietz and Michael Bitzer
Mol Ther 13: S390-S390; doi:10.1016/j.ymthe.2006.08.1107
1014. Regulation of Extracellular Matrix Gene Expression in Renal Mesangial Cells by Transcription Factors Sp1 and CREB
Davis W. Cheng and Lalit P. Singh
Mol Ther 13: S390-S390; doi:10.1016/j.ymthe.2006.08.1108
1015. Assessment of Zinc Finger-FOKI Chimeric Endonuclease Activity Using a Single Strand Annealing Assay in Mammalian Cells
Vincent Brondani and David J. Segal
Mol Ther 13: S390-S391; doi:10.1016/j.ymthe.2006.08.1109
1016. Modulation of Transgene Expression: DNA Methylation Is, at Best, Only Partly Responsible
Marlene S. Strayer, Gongyi Ren, Martyn K. White, Dawn Maier and David S. Strayer
Mol Ther 13: S391-S391; doi:10.1016/j.ymthe.2006.08.1110
1017. Genetic Predisposition of the Sensitivity of Prostate Cancer to Radiatherapy
Lilach Agemy, Zelig Eshhar, Itai Kela, Eytan Domany, Avi Orr-Urtreger, Anat Bar-Shira and M. Raphael Pfeffer
Mol Ther 13: S391-S391; doi:10.1016/j.ymthe.2006.08.1111
1018. Stem Cell Gene Therapy: Toward a Universal Platform Relying on Custom Endonuclease-Boosted Gene Targeting, Cybridization, Transient Regenerative/Epigenetic Gene Therapy and Synergistic Combinations
Roger Bertolotti
Mol Ther 13: S392-S392; doi:10.1016/j.ymthe.2006.08.1112
1019. Development of Tissue-Specific RNAi for Gene Therapy
Danny Allen, Paul F. Kenna, Arpad Palfi, Helena McMahon, Sophia Millington-Ward, Mary O'Reilly, Peter Humphries and G. Jane Farrar
Mol Ther 13: S392-S392; doi:10.1016/j.ymthe.2006.08.1114
1020. AAV Delivery of Suppression and Replacement Constructs for Rhodopsin-Linked Autosomal Dominant Retinitis Pigmentosa
Naomi Chadderton, Arpad Palfi, Mary O'Reilly, Sophia Millington-Ward, Marius Ader, Markus Hildinger, Alberto Auricchio, Gearoid Tuohy, Peter Humphries, Paul F. Kenna and G. Jane Farrar
Mol Ther 13: S392-S393; doi:10.1016/j.ymthe.2006.08.1115
1021. Suppression and Replacement Strategies for Rhodopsin-Linked Autosomal Dominant Retinitis Pigmentosa
Arpad Palfi, Mary O'Reilly, Sophia Millington-Ward, Marius Ader, Naomi Chadderton, Gearoid Tuohy, Anna-Sophia Kiang, Niamh McNally, Marian Humphries, Peter Humphries, Paul F. Kenna and G. Jane Farrar
Mol Ther 13: S393-S393; doi:10.1016/j.ymthe.2006.08.1116
1022. Efficient Dystrophin Production in Response to Local and Systemic Administration of Morpholino Antisense Oligonucleotides in the Mdx Mouse
Ian R. Graham, Francesca C. Thorogood, Helen Foster and George Dickson
Mol Ther 13: S393-S393; doi:10.1016/j.ymthe.2006.08.1117
1023. New Generation of shRNA for Targeted Cancer Gene Therapy
Donald D. Rao, David Taube, Padma Kumar, Phil Maples and John Nemunaitis
Mol Ther 13: S393-S394; doi:10.1016/j.ymthe.2006.08.1118
1024. Encapsulation of the NF-kB Decoy Oligonucleotide in Echogenic Liposomes and Its Ultrasound-Triggered Release
Kyle D. Buchanan, ShaoLing Huang, Susan D. Tiukinhoy-Laing, David D. McPherson and Robert C. MacDonald
Mol Ther 13: S394-S394; doi:10.1016/j.ymthe.2006.08.1119
1025. Therapeutic Effect of a Self-Cleaving Hammerhead Ribozyme in a Mouse Model of Osteogenesis Imperfecta
Belinda E. Peace, Christopher J. Frede, Jane B. Florer, Michael W. Kilpatrick, Petros Tsipouras and Richard J. Wenstrup
Mol Ther 13: S394-S394; doi:10.1016/j.ymthe.2006.08.1120
1026. Manipulation of S Phase Progression Can Counteract Cell Cycle Arrest of Corrected Cells during the Oligonucleotide-Directed Gene Repair Reaction
Luciana Ferrara, Julia Engstrom and Eric Kmiec
Mol Ther 13: S395-S395; doi:10.1016/j.ymthe.2006.08.1121
1027. DNase II Knockdown in Human Endothelial Cells Does Not Improve Non-Viral Transfection Efficiency
Gregory A. Barker and Scott L. Diamond
Mol Ther 13: S395-S395; doi:10.1016/j.ymthe.2006.08.1122
1028. Use of Antisense Oligonucleotides To Restore Activity in Mutant p53
Daniel J. Catron, Paloma H. Giangrande and Bruce A. Sullenger
Mol Ther 13: S395-S395; doi:10.1016/j.ymthe.2006.08.1123
1029. Single-Stranded Oligonucleotide Gene Targeting in Mouse Embryonic Stem Cells
Brian R. Murphy, Scott L. Diamond and Eric A. Pierce
Mol Ther 13: S395-S396; doi:10.1016/j.ymthe.2006.08.1124
1030. Pyrazolo[3,4-d]Pyrimidine Guanine Base Substitution in Triplex Forming Oligonucleotides Improves Target Specificity and Chromosomal Mutagenesis
Joanna Y. Chin, Janice A. Lloyd, Faye A. Rogers and Peter M. Glazer
Mol Ther 13: S396-S396; doi:10.1016/j.ymthe.2006.08.1125
1031. Improved Intranuclear Delivery of PNA-Peptide Conjugates Designed for Chromosomal Gene Targeting
Faye A. Rogers and Peter M. Glazer
Mol Ther 13: S396-S396; doi:10.1016/j.ymthe.2006.08.1126
1032. rAAV Mediated Knock-Down of Tyrosine Hydroxylase in the Substantia Nigra Using a pol II Transcribed siRNA
Fredric P. Manfredsson, Ronald J. Mandel, Sergei Zolotukhin and Alfred S. Lewin
Mol Ther 13: S396-S396; doi:10.1016/j.ymthe.2006.08.1127
1033. Tightly Controlled and Reversible Knockdown of Gene Expression Using Lentiviral Vectors Encoding Tetracycline-Dependent Repressors or Transactivators
Krzysztof Pluta, William Diehl, Robert H. Kutner, Xian-Yang Zhang and Jakob Reiser
Mol Ther 13: S396-S397; doi:10.1016/j.ymthe.2006.08.1128
1034. Expression of Short Hairpin RNAs by Liver and Non Liver Specific RNA Pol II Expression Cassettes: What Governs Activity?
David A. Suhy, Alexander A. Kolykhalov, Linda B. Couto, Luz-Maria Garcia, Annette R. Schroeder, Amy E. Parker, Gabriel Haniff, Mark A. Kay and Peter W. Roelvink
Mol Ther 13: S397-S397; doi:10.1016/j.ymthe.2006.08.1129
1035. Short G-Rich Oligonucleotides as a Therapeutic for Huntingtonss Disease
Michael Skogen, Jennifer Roth, Hetal Parekh-Olmedo and Eric Kmiec
Mol Ther 13: S397-S397; doi:10.1016/j.ymthe.2006.08.1130
1036. Overcoming Suppression of Oligonucleotide-Directed Targeted Gene Repair in Mammalian Cells
Katie Maguire, Timothy Schwartz and Eric Kmiec
Mol Ther 13: S397-S397; doi:10.1016/j.ymthe.2006.08.1131
1037. Formulating and Testing of Targeted siRNA for Applications In Vivo
Marie McAnuff, Garrett Rettig, Ji-seon Kim, Dijie Liu, Changpo Chen, Molly Martin and Kevin Rice
Mol Ther 13: S397-S398; doi:10.1016/j.ymthe.2006.08.1132
1038. Therapy of Cancer by Inhibition of XIAP with RNAi Mediated by Tumor Specific Replicating Adenovirus
Qiuwei Pan, Rong Cai, Kai Chen, Xubin Wei, Yu Chen, Xinyuan Liu and Cheng Qian
Mol Ther 13: S398-S398; doi:10.1016/j.ymthe.2006.08.1133
1039. Targeted Catabolic Gene Knockdown Using RNA Interference in Chondrocytes Abrogates the IL-1|[beta]| Response for Arthritis Control
Alan Nixon and Lisa Strassheim
Mol Ther 13: S398-S398; doi:10.1016/j.ymthe.2006.08.1134
1040. Towards Gene Correction Therapy for Wiskott-Aldrich Syndrome Using Designed Zinc Finger Endonucleases
Brian R. Davis, Nicole L. Prokopishyn, Jonathan Rosenberg, Michael DiCola, Jennifer Brosius, R. Michael Blaese, Richard A. Metz, Lei Zhang, Danny Xia, Jeffrey C. Miller, Kenneth Kim, Fyodor D. Urnov, Philip D. Gregory and Michael C. Holmes
Mol Ther 13: S398-S399; doi:10.1016/j.ymthe.2006.08.1136
1041. Ex Vivo Soluble Fas Ligand Treatment of Donor Cells to Selectively Reduce Murine Acute Graft Versus Host Disease
Robert W. Georgantas, Osnat Bohana-Kashtan and Curt I. Civin
Mol Ther 13: S399-S399; doi:10.1016/j.ymthe.2006.08.1137
1042. Tracking and Gene Expression Profile of Bone Marrow Mesenchymal Stem Cells Injected into Pig Myocardium by Magnetic Resonance Imaging and Laser-Capture Microdissection
Elie R. Chemaly, Irina Pomerantseva, Ryuichi Yoneyama, Djamel Lebeche, Davide Gianni, Kozo Hoshino, Yoshiaki Kawase, Federica del Monte and Roger J. Hajjar
Mol Ther 13: S399-S400; doi:10.1016/j.ymthe.2006.08.1138
1043. Intravenous (I.V.) Administration of Manganese Superoxide Dismutase-Plasmid Liposome (MnSOD-PL) Complex Protects Mice from Whole Body Irradiation
Michael W. Epperly, Yunyun Niu and Joel S. Greenberger
Mol Ther 13: S400-S400; doi:10.1016/j.ymthe.2006.08.1139
1044. Mesenchymal Stem Cell-Mediated Gene Delivery of Bone Morphogenetic Protein-2 in Alginate in an Articular Fracture Model
Terri A. Zachos, Steven E. Weisbrode and Alicia L. Bertone
Mol Ther 13: S400-S400; doi:10.1016/j.ymthe.2006.08.1140
1045. Targeted Elimination of the Brain Tumor Initiating Cell Population with Adoptively Transferred T Cells
Christine E. Brown, Renate Starr, Dorota Korta, Brenda Aguilar and Michael C. Jensen
Mol Ther 13: S401-S401; doi:10.1016/j.ymthe.2006.08.1141
1046. Derivation of Functionally Normal Macrophages from Human Embryonic Stem (hES) Cells for HIV-1 Gene Therapy
Joseph S. Anderson, Sriram Bandi, Dan S. Kaufman and Ramesh Akkina
Mol Ther 13: S401-S401; doi:10.1016/j.ymthe.2006.08.1142
1047. Neural Progenator Cells Can Be Genetically-Modified by a Novel Double-Stranded Adeno-Associated Viral (AAV) Vectors
Chi-Hsieh Wang, Ga-Chen Yin, Xiao Xiao, Hsin-I. Ma and Yung-Hsiao Chiang
Mol Ther 13: S401-S401; doi:10.1016/j.ymthe.2006.08.1143
1048. Gene-Enhanced Mesenchymal Stem Cells for the Treatment of Tendinitis
Alan J. Nixon and Jennifer L. Haupt
Mol Ther 13: S402-S402; doi:10.1016/j.ymthe.2006.08.1144
1049. Regenerative Cell Therapy for White Matter Disorders
Ana Olariu, Jeremy Francis, Scott McPhee, Eiji Kobayashi and Paola Leone
Mol Ther 13: S402-S402; doi:10.1016/j.ymthe.2006.08.1145
1050. Mouse Embryonic Endothelial Progenitor Cells Home to Atherosclerotic Lesions after Intravenous Delivery
Ba-bie Teng, Eva Zsigmond and Kathyjo Jackson
Mol Ther 13: S402-S403; doi:10.1016/j.ymthe.2006.08.1146
1051. BMP2 Induced Chondrogenesis: Can Monocytic Progenitors Differentiate into Chondrocytes?
Alan R. Davis, Jessica Shafer, Francis H. Gannon, Christine Fouletier-Dilling, Zawaunyka Lazard, Zbigniew Gugala, Michael H. Heggeness and Elizabeth A. Olmsted-Davis
Mol Ther 13: S403-S403; doi:10.1016/j.ymthe.2006.08.1147
1052. In Vivo Repopulation Ability of Genetically Corrected Bone Marrow Cells from Fanconi Anemia Patients
Odile Cohen-Haguenauer, Bruno Peault, C|[eacute]|cile Bauche, Marie-Th|[eacute]|r|[egrave]|se Daniel, Ibrahim Casal, Vincent Levy, Jean Dausset, Michel Boiron, Christian Auclair, Eliane Gluckman and Michel Marty
Mol Ther 13: S403-S403; doi:10.1016/j.ymthe.2006.08.1148
1053. Functional Restoration of a Genetic Defect in Multipotent Germline Stem Cells by Human Artificial Chromosome Containing a Genomic Insert
Yasuhiro Kazuki, Hidetoshi Hoshiya, Yoshiteru Kai, Satoshi Abe, Masato Takiguchi, Mitsuhiko Osaki, Mito Kanatsu- Shinohara, Naoyo Kajitani, Yasuaki Shirayoshi, Masaharu Hiratuka, Astuo Ogura, Takashi Shinohara and Mitsuo Oshimura
Mol Ther 13: S403-S404; doi:10.1016/j.ymthe.2006.08.1149
1054. Hematopoietic and Non-Hematopoietic Engraftment after Bone Marrow Transplantation in Newborn Mice
Emanuela M. Bruscia, Joanna E. Price, Elizabeth Ziegler and Diane S. Krause
Mol Ther 13: S404-S404; doi:10.1016/j.ymthe.2006.08.1150
1055. High Levels of Human Factor IX Expression in Hemophilia B Mice after Adult Stem Cell-Based Gene Therapy Combined with Non-Myeloablative Conditioning
Alex H. Chang, Leszek Lisowski and Michel Sadelain
Mol Ther 13: S404-S404; doi:10.1016/j.ymthe.2006.08.1151
1056. Failure of an Insulator Element To Prevent Retroviral Insertional Activation of Oncogenes and Lymphomagenesis
Koyel Mitra and Jack Lenz
Mol Ther 13: S405-S405; doi:10.1016/j.ymthe.2006.08.1153
1057. The cHS4 Chromatin Insulator Blocks Epigenetic Interactions between Integrated Vectors and the Surrounding Genome
Changlong Li and David W. Emery
Mol Ther 13: S405-S405; doi:10.1016/j.ymthe.2006.08.1154
1058. Suppression of Clonal Dominance in Cultured Human Lymphoid Cells by Addition of the 5|[prime]|cHS4 Insulator to a Lentiviral Vector
Marguerite V. Evans-Galea, Matthew M. Wielgosz, Hideki Hanawa and Arthur W. Nienhuis
Mol Ther 13: S405-S406; doi:10.1016/j.ymthe.2006.08.1155
1059. The Influence of a Chromatin Insulator on Interactions between Globin Regulatory Elements and Cellular Promoters in Erythroid Cells
Byoung Y. Ryu, Derek A. Persons and Arthur W. Nienhuis
Mol Ther 13: S406-S406; doi:10.1016/j.ymthe.2006.08.1156
1060. The MSCV-U3 Internal Promoter Strongly Activates Surrounding Cellular Promoter in Combination with Self-Inactivating (SIN)-MSCV Vector Backbone
Hideki Hanawa and Takashi Shimada
Mol Ther 13: S406-S407; doi:10.1016/j.ymthe.2006.08.1157
1061. Upstream Polyadenylation Enhancers in the U3 Region of Self-Inactivating Retroviral and Lentiviral Vectors Improve Titer and Gene Expression, and Prevent Transcriptional Read-Through
Axel Schambach, Melanie Galla and Baum Christopher
Mol Ther 13: S407-S407; doi:10.1016/j.ymthe.2006.08.1158
1062. Intracerebellar Injection of AAV-IGF-1 Improves Motor Function and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis
James C. Dodge, Marco A. Passini, Jennifer Clarke, Liza Grissett, Soo Hyun Kim, Rita Wen, Tatyana V. Taksir, Denise A. Griffiths, Seng H. Cheng, Brian K. Kaspar and Lamya S. Shihabuddin
Mol Ther 13: S407-S407; doi:10.1016/j.ymthe.2006.08.1160
1063. Optimizing Intron Splicing Signal Overcomes the mRNA Accumulation Barrier in Trans-Splicing AAV Vectors
Yi Lai and Dongsheng Duan
Mol Ther 13: S407-S408; doi:10.1016/j.ymthe.2006.08.1161
1064. Haute Couture Vectors: Solving Clinical Problems with Custom Designed AAV Vectors
Dawn E. Bowles, Chengwen Li, Paul E. Monahan, Joseph E. Rabinowitz, Mavis McKenna and Jude Samulski
Mol Ther 13: S408-S408; doi:10.1016/j.ymthe.2006.08.1162
1065. AAV2 Vector-Delivered Myostatin Propeptide Improves Muscle Healing after Injury
Jinhong Zhu, Yong Li, Chunping Qiao, Xiao Xiao and Johnny Huard
Mol Ther 13: S408-S409; doi:10.1016/j.ymthe.2006.08.1163
1066. A Novel Class of Miniature Stabilized Double-Stranded AAV (msdsAAV) Vectors for the In Vivo Expression of Short Hairpin RNAs
Dirk Grimm, Joyce S. Lee, Konrad L. Streetz, Theresa A. Storm and Mark A. Kay
Mol Ther 13: S409-S409; doi:10.1016/j.ymthe.2006.08.1164
1067. Amelioration of Arthritis after Local Delivery of an Adeno-Associated Virus Type 6 Expressing a TNF-Blocking Agent under a Disease-Inducible Promoter
Maroun Khoury, Jan Adriaansen, Pascale Louis-Plence, Dani|[egrave]|le Noel, Pascal Bigey, C. de Cortie, David Gould, Margriet Vervoordeldonk, Daniel Scherman, Paul-Peter Tak, Christian Jorgensen and Florence Apparailly
Mol Ther 13: S409-S409; doi:10.1016/j.ymthe.2006.08.1165
1068. Plasmid DNA Sequences Present in Conventional HSV Amplicon Vectors Cause and Rapid Transgene Silencing by Inactive Chromatin Formation
Masataka Suzuki, Kazue Kasai and Yoshinaga Saeki
Mol Ther 13: S410-S410; doi:10.1016/j.ymthe.2006.08.1167
1069. The HSV-2 Vector |[Delta]|RR Prevents Excitotoxicity-Induced Neuronal Cell Loss through Activation of Survival Pathways and Glial Cell Modulation
Jennifer M. Laing, Michael D. Gober and Laure Aurelian
Mol Ther 13: S410-S410; doi:10.1016/j.ymthe.2006.08.1168
1070. Infectious Delivery and Prolonged Expression of a 135 kb Human Friedreich's Ataxia Genomic DNA Locus in Human and Mouse Neuronal Cells
Silvia Gomez-Sebastian, Alfredo Gimenez-Cassina, Javier Diaz-Nido, Filip Lim and Richard Wade-Martins
Mol Ther 13: S410-S411; doi:10.1016/j.ymthe.2006.08.1169
1071. Development and Characterization of HSV-1 Vector-Expressed Dominant Negative PKC epsilon for Pain Therapy
Rahul Srinivasan, Adrian Sculptoreanu, Darren Wolfe, James Wechuck, Simon Watkins, William C. de Groat and Joseph C. Glorioso
Mol Ther 13: S411-S411; doi:10.1016/j.ymthe.2006.08.1170
1072. Delivery of Oncolytic Herpes Simplex Virus to Infiltrative Brain Tumor Sites Via Neuronal Stem Cells
Tyler T. Voss, Kevin R. Bobbitt, Chaya Brodie, Evan Synder and Cathie G. Miller
Mol Ther 13: S411-S411; doi:10.1016/j.ymthe.2006.08.1171
1073. Cell Tropism of JC-Virus Derived Viral-Like Particles In Vitro and In Vivo
Perry Liu, Linda Cashion, Hu Sheng Qian, Oliver Ast, Andrzej Citkowicz, Susan Harvey, Branka Mitrovic, Mary Rose Masikat, Brent Larsen, Richard N. Harkins, Gabor M. Rubanyi and Harald Petry
Mol Ther 13: S411-S412; doi:10.1016/j.ymthe.2006.08.1172
1074. Interaction of LPD Nanoparticles with Dendritic Cells
Lisa M. Shollenberger and Leaf Huang
Mol Ther 13: S412-S412; doi:10.1016/j.ymthe.2006.08.1174
1075. Cellular Localization and Cell Cycle Dynamics of |[phiv]|C31 Integrase in Mammalian Cells
Robert T. Hillman, Lauren E. Woodard and Michele P. Calos
Mol Ther 13: S412-S412; doi:10.1016/j.ymthe.2006.08.1175
1076. Mechanism of Naked DNA Clearance after Intravenous Injection
Feng Liu, Lisa M. Shollenberger, Christine C. Conwell, Xing Yuan and Leaf Huang
Mol Ther 13: S412-S413; doi:10.1016/j.ymthe.2006.08.1176
1077. Sequences from the Human Type 1|[alpha]|2 Procollagen Promoter Mediate Osteoblast-Specific Plasmid Nuclear Import
David A. Dean, Cindy Stivers, Tom A. Linkhart and Donna D. Strong
Mol Ther 13: S413-S413; doi:10.1016/j.ymthe.2006.08.1177
1078. Silencing of Transgene Expression Following Plasmid Based Delivery to Murine Skeletal Muscle Is Dose Dependent
Alan R. Brooks, Faye Wu, Perry Liu, Hu Sheng Qian, Peiyin Wang, Heather Gibson, Katalin Kauser, Rick N. Harkins and Gabor M. Rubanyi
Mol Ther 13: S413-S413; doi:10.1016/j.ymthe.2006.08.1178
1079. Effect of WPRE on Transgene Expression Using Different Promoters in the Context of Hydrodynamically Delivered Plasmid Vectors
Astrid Pa|[ntilde]|eda, Lucia Vanrell, Ruben Hernande-Alcoceba, Rafael Enriquez de Salamanca, Jesus Prieto, Gloria Gonzalez-Aseguinolaza and Antonio Fontanellas
Mol Ther 13: S413-S413; doi:10.1016/j.ymthe.2006.08.1179
1080. Receptor-Targeting Smart Vectors for Efficient Gene Transfer to Tumours
Stephanie Grosse, Martin Elbs, John Wong, Alethea Tabor, Helen Hailes and Stephen Hart
Mol Ther 13: S414-S414; doi:10.1016/j.ymthe.2006.08.1181
1081. Targeted Nanocapsules for Liver Cell-Type Delivery of Plasmids In Vivo
Betsy T. Kren, Gretchen M. Unger, Mark T. Reding and Clifford J. Steer
Mol Ther 13: S415-S415; doi:10.1016/j.ymthe.2006.08.1182
1082. Delivery of Anti-Oxidative Enzyme Genes Protects Against Ischemia/Reperfusion-Induced Liver Injury in Mice
Song-Qing He, Yan-Hong Zhang, Senthil K. Venugopal, Christopher W. Dicus, Richard V. Perez, Mark A. Zern, Michael H. Nantz and Jian Wu
Mol Ther 13: S415-S415; doi:10.1016/j.ymthe.2006.08.1183
1083. Crosslinked PEI Polyplexes for Light-Triggered DNA Release
Rachel G. Handwerger, Moon-Suk Kim and Scott L. Diamond
Mol Ther 13: S415-S416; doi:10.1016/j.ymthe.2006.08.1184
1084. Converting Non-Infectious Virus-Like Particles into Hybrid Gene Therapy Vectors Using Polyethylenimine
Josh D. Ramsey and Daniel W. Pack
Mol Ther 13: S416-S416; doi:10.1016/j.ymthe.2006.08.1185
1085. In Vivo Imaging of Microencapsulated Gene Therapy
Anna Li, Donna Hou, Feng Shen, Eric P. Seidlitz, Patricia L. Chang and Murray A. Potter
Mol Ther 13: S416-S416; doi:10.1016/j.ymthe.2006.08.1186
1086. T Cell Responses to Canine Factor IX and AAV Capsid Antigens in Hemophilia B Dogs after Intravascular Gene Delivery to Skeletal Muscle
Daniel J. Hui, Federico Mingozzi, Aaron Dillow, Stephanie McCorquodale, Timothy C. Nichols, Valder R. Arruda and Katherine A. High
Mol Ther 13: S417-S417; doi:10.1016/j.ymthe.2006.08.1188
1087. Balloon Occlusion Catheter-Based Delivery of HDAd into the Nonhuman Primate Liver Results in Stable, High Level Transgene Expression with Minimal Toxicity
Nicola Brunetti-Pierri, Gary Stapleton, Donna Palmer, Yu Zuo, Arthur Beaudet, Charles Mullins and Philip Ng
Mol Ther 13: S417-S417; doi:10.1016/j.ymthe.2006.08.1189
1088. Stem Cell Gene Therapy with No Pre-Conditioning for the ADA-Deficiency Patients Leads to Generalized Detoxification and Delayed, but Steady Hematological Reconstitution
Makoto Otsu, Satoru Nakajima, Miyuki Kida, Yoshihiro Maeyama, Nariaki Toita, Norikazu Hatano, Nobuaki Kawamura, Ryouji Kobayashi, Osamu Tatsuzawa, Masafumi Onodera, Fabio Candotti, Pawan Bali, Michael S. Hershfield, Yukio Sakiyama and Tadashi Ariga
Mol Ther 13: S418-S418; doi:10.1016/j.ymthe.2006.08.1190
1089. Neonatal BMT of ADA-Deficient SCID Mice Results in Phenotypic Correction Despite Low Levels of Engraftment and Absence of the Selective T Lymphoid Expansion Seen in |[gamma]|c Gene Knock-Out Mice
Denise A. Carbonaro, Xiangyang Jin, Xiao-Jin Yu, Dianne Skelton and Donald B. Kohn
Mol Ther 13: S418-S418; doi:10.1016/j.ymthe.2006.08.1191
1090. Enzyme Replacement Therapy with Pegylated Adenosine Deaminase (PEG-ADA) Does Not Impede Immune Reconstitution Following Transplantation of Gene-Corrected Bone Marrow Cells in the Murine Model of ADA-SCID
Denise A. Carbonaro, Xiangyang Jin, Karen Pepper and Donald B. Kohn
Mol Ther 13: S419-S419; doi:10.1016/j.ymthe.2006.08.1192
1091. Successful Induction of Immune Tolerance to Canine Factor VIII after Lentiviral-Mediated Gene Therapy in Neonatal Hemophilia A Mice
Hideto Matsui, Masaru Shibata, Brian Brown, Andrea Labelle, Carol Hegadorn, Chandler Andrews, Marinee Chuah, Thierry VandenDriessche, Carol H. Miao, Christine Hough and David Lillicrap
Mol Ther 13: S419-S419; doi:10.1016/j.ymthe.2006.08.1193
1092. Clinical Studies of Intra-Articular Administration of a Recombinant Adeno-Associated Vector Containing a TNF-|[alpha]| Antagonist Gene in Inflammatory Arthritis
Alison Heald, Greg Pate and Pervin Anklesaria
Mol Ther 13: S419-S420; doi:10.1016/j.ymthe.2006.08.1195
1093. Ex Vivo Gene Therapy Approach Using Human Lim Mineralization Protein-3 To Induce Bone Healing in a Rodent Model
Enrico Pola, Wanda Lattanzi, Giandomenico Logroscino, Giovanni Pecorini, Anna Tampieri, Andrea Gambotto, Carlo A. Logroscino and Paul D. Robbins
Mol Ther 13: S420-S420; doi:10.1016/j.ymthe.2006.08.1196
1094. Self-Complementary Vectors Significantly Enhance AAV-Mediated Gene Transfer to Joint Tissues
Jesse Kay, Elvire Gouze, Kenneth Warrington Jr., Irene Zolotukhin, Rachael Watson, Marsha Bush, Jeetpaul Saran, Jean-Noel Gouze, Douglas McCarty, Paul Robbins, Christopher Evans and Steven Ghivizzani
Mol Ther 13: S420-S421; doi:10.1016/j.ymthe.2006.08.1197
1095. Gene-Induced Chondrogenesis of Mesenchymal Stem Cells: A Comparative Analysis of Candidate cDNAs
Jeetpaul Saran, Marsha Bush, Jean-Noel Gouze, Rachael Watson, Jesse Kay, Andre Steinert, Elvire Gouze and Steven Ghivizzani
Mol Ther 13: S421-S421; doi:10.1016/j.ymthe.2006.08.1198
1096. FSTL-1 Is a Novel Pro-Inflammatory Protein
Takako Miyamae, Anthony D. Marinov, David C. Wilson and Raphael Hirsch
Mol Ther 13: S421-S421; doi:10.1016/j.ymthe.2006.08.1199
1097. Retroviral Delivery of the RheoSwitch|[reg]| Therapeutic System for Precisely Regulated Expression of BMP-2 for Bone Regeneration
Anand K. Katakam, J. Kelly Ganjei, Youngsuk Yi, Dug Keun Lee, Moon Jong Noh, Kwan Hee Lee, Dean E. Cress and Prasanna Kumar
Mol Ther 13: S422-S422; doi:10.1016/j.ymthe.2006.08.1200
1098. How Morbilliviruses Antagonize Innate Immunity and Swiftly Inactivate the Adaptive Immune System
Veronika von Messling, Nicholas Svitek and Roberto Cattaneo
Mol Ther 13: S422-S422; doi:10.1016/j.ymthe.2006.08.1202
1099. RNAi-Based Therapy for the Treatment of HCV
Linda B. Couto, Amy E. Parker, Gabriel Haniff, David A. Suhy, Alexander A. Kolykhalov, Peter W. Roelvink, Luz Maria Garcia, Rosanna Schroeder, Mark A. Kay and Sara M. Cunningham
Mol Ther 13: S422-S423; doi:10.1016/j.ymthe.2006.08.1203
1100. Baculovirus Vectors for Malaria Vaccination
Robert Strauss, Andreas Huser, Shaoheng Ni, Salif Sow, Nancy Kiviat, Christian Hofmann and Andre Lieber
Mol Ther 13: S423-S423; doi:10.1016/j.ymthe.2006.08.1204
1101. Rapid and Long-Term Protection Against Anthrax Lethal Toxin
Julie L. Boyer, Kazuhiko Kasuya, Jeffrey Howard, Neil R. Hackett, James M. Wilson and Ronald G. Crystal
Mol Ther 13: S423-S423; doi:10.1016/j.ymthe.2006.08.1205
1102. Genetically Engineered Bifidobacterium animalis Expressing Salmonella flagellin Gene for the Mucosal Immunization in Mouse Model
Toshiro Shirakawa, Tetsuo Takata, Akinobu Gotoh, Yasunobu Kano and Masato Kawabata
Mol Ther 13: S424-S424; doi:10.1016/j.ymthe.2006.08.1206
1103. Augmentation of Immunity Against AAV- Encoded Transgenes by Use of the Genetic Adjuvants C3d3 and CTLA4
Grant J. Logan, Zheng Maolin, Coppel L. Ross, Rowe B. Peter, Wang Lina and Alexander E. Ian
Mol Ther 13: S424-S424; doi:10.1016/j.ymthe.2006.08.1207
1104. Phase II Study of Lucanix|[trade]| a Transforming Growth Factor |[beta]|2 (TGF-|[beta]|2) Antisense Gene Modified Allogeneic Tumor Cell Vaccine in Non Small Cell Lung Cancer (NSCLC)
John Nemunaitis, Robert O. Dillman, Paul O. Schwarzenberger, Neil Senzer, Casey Cunningham, Jodi Cutler, Alex Tong, Padmasini Kumar, Beena Pappen, Cody Hamilton, Edward DeVol, Phillip B. Maples, Lily Liu, Terry Chamberlin, Daniel L. Shawler and Habib Fakhrai
Mol Ther 13: S424-S425; doi:10.1016/j.ymthe.2006.08.1209
1105. A Phase I Clinical Trial of an IL-12 Gene Plasmid Formulated with a Novel Lipopolymeric Gene Delivery System for Intraperitoneal Treatment of Recurrent Ovarian Cancer
Ronald D. Alvarez, Mack N. Barnes, Connie McCombs, Sharmila Makhija, Jason Fewell, Danny H. Lewis and Kursheed Anwer
Mol Ther 13: S425-S425; doi:10.1016/j.ymthe.2006.08.1210
1106. Results of a Phase I Clinical Trial of Adenoviral-Interferon-Beta Gene Therapy for Malignant Mesothelioma and Malignant Pleural Effusions
Daniel H. Sterman, Adriana Recio, Andrew Haas, Michael Machuzak, Colin Gillespie, Jing Sun, Veena Kapoor, Leslie A. Litzky, Robert Vonderheide, Carl June, John C. Kucharczuk, Larry R. Kaiser and Steven M. Albelda
Mol Ther 13: S425-S425; doi:10.1016/j.ymthe.2006.08.1211
1107. Gene Therapy Clinical Trials for Relapsed Leukemia with Infusions of the Suicide-Gene Transduced Donor Lymphocytes in Japan
Masafumi Onodera, Shin Kaneko, Makoto Otsu, Hiroshi Kojima, Ryo Sumazaki, Salvatore Toma, Chiara Bonini, Claudio Bordignon, Hiromitsu Nakauchi and Toshiro Nagasawa
Mol Ther 13: S426-S426; doi:10.1016/j.ymthe.2006.08.1212
1108. High Rate of Anti-Tumor Immune Responses in a Phase 1 Clinical Trial of Adenoviral-Interferon-Beta Gene Transfer for Malignant Mesothelioma (MM) and Malignant Pleural Effusions (MPE)
Steven M. Albelda, Andrew Haas, Collin Gillespie, Andriana Recio, Jing Sun, Veena Kapoor, Jennifer Brown, Parr Michael, Mitchell Ho, Ira Pastan, Robert H. Vonderheide, Richard Carroll, Carl June, Larry R. Kaiser and Daniel H. Sterman
Mol Ther 13: S426-S426; doi:10.1016/j.ymthe.2006.08.1213
1109. Targeting CYP1B1 with a Therapeutic Cancer Vaccine: Results of Preclinical and Clinical Studies
Mary Lynne Hedley
Mol Ther 13: S426-S426; doi:10.1016/j.ymthe.2006.08.1214
1110. Engineering Cell Lines for the Production of Highly Replication Defective HSV-1 Vectors
Kyle G. Grant, David M. Krisky, Mohammed M. Ataai and Joseph C. Glorioso III
Mol Ther 13: S427-S427; doi:10.1016/j.ymthe.2006.08.1216
1111. Removal of Empty Particles from Type 1 Adeno-Associated Virus Vector Stocks by Ion Exchange Chromatography Potentiates Transgene Expression
Masashi Urabe, Ke-Qin Xin, Yoko Obara, Takayo Nakakura, Hiroaki Mizukami, Akihiro Kume, Kenji Okuda and Keiya Ozawa
Mol Ther 13: S427-S427; doi:10.1016/j.ymthe.2006.08.1217
1112. Design and Implementation of VRX496 Phase II Cell Processing for cGMP Production of Multiple Doses of Lentivirally Transduced Autologous HIV Infected CD4+ T Lymphocytes
Laurent Humeau, Reuben Cohen, Tony Encinas, Yelena Skripchenko, Franck Lemiale, Kris Andre, Arvind Chopra, Tessio Rebello and Vladimir Slepushkin
Mol Ther 13: S427-S427; doi:10.1016/j.ymthe.2006.08.1218
1113. Large Scale Ex Vivo Expansion of Human T Cells under GMP Conditions Consistently Yields Fully Functional T Cells In Vivo Proven by Induction of Lethal GvHD in a Mouse Xenotransplant Model
Gerhard Bauer, Jon Walker, Bruno Nervi, Julie Ritchey, Mike Rettig, Jackie Hughes, Bill Eades, Jan Nolta and John DiPersio
Mol Ther 13: S428-S428; doi:10.1016/j.ymthe.2006.08.1219
1114. Bone Regeneration by Osteogenic Gene Delivery without Cell Transplantation Using Supramolecular Nanocarrier
Keiji Itaka, Kayo Masago, Shinsuke Oba, Ung-il Chung and Kazunori Kataoka
Mol Ther 13: S428-S429; doi:10.1016/j.ymthe.2006.08.1220
1115. A Simple Method for the Purification of Lentiviral Vectors Using a Combination of Ultrafiltration and Anion Exchange Chromatography
Rachel M. Koldej and Donald S. Anson
Mol Ther 13: S429-S429; doi:10.1016/j.ymthe.2006.08.1221
