TABLE 1
FROM:
Efficient Hepatic Delivery and Expression from a Recombinant Adeno-associated Virus 8 Pseudotyped 
1-Antitrypsin Vector
Thomas J. Conlon, Travis Cossette, Kirsten Erger, Young-Kook Choi, Tracy Clarke, Marda Scott-Jorgensen, Sihong Song, Martha Campbell-Thompson, James Crawford and Terence R. Flotte
BACK TO ARTICLETABLE 1. AAV genome counts do not reflect transgene expression
| Dose Group | Copies/Cell |
|---|---|
| Low (1.65e9) | 0.18  0.24 |
| Medium (1.65e10) | 6.74 13.04 |
| High (1.65e11) | 5.38 5.10 |
Real-time PCR using liver tissue excised during partial hepatectomy determined genome copy numbers. 1 
g of tissue was subjected to quantitation using primers specific for the CMV enhancer/chicken 
-actin promoter present in the ITR vector. Total copies per cell were determined using the standard 6 pg/diploid genome factor. Means standard deviation after subtraction of PBS control background values are presented.
