TABLE OF CONTENTS
Volume 12, Issue 4 (October 2005)
Inside This Month |
Research Update |
Reviews |
Original Articles |
Short Communication |
Errata
Editorial
Stakeholders' Conference Sharpens Focus on Challenges of Clinical Gene Transfer
Katherine A. High
Mol Ther 12: 581-582; doi:10.1016/j.ymthe.2005.08.015
Inside This Month
Top of pageResearch Update
Top of pageReviews
Gene Therapy for Malignant Glioma: Current Clinical Status
Kalevi J. Pulkkanen and Seppo Yla-Herttuala
Mol Ther 12: 585-598; doi:10.1016/j.ymthe.2005.07.357
What Does It Take to Bind CAR?
Lane K. Law and Beverly L. Davidson
Mol Ther 12: 599-609; doi:10.1016/j.ymthe.2005.05.017
Original Articles
Custom Zinc-Finger Nucleases for Use in Human Cells
Stephen Alwin, Maja B. Gere, Eva Guhl, Karin Effertz, Carlos F. Barbas III, David J. Segal, Matthew D. Weitzman and Toni Cathomen
Mol Ther 12: 610-617; doi:10.1016/j.ymthe.2005.06.094
Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice
Edgardo Rodriguez-Lebron, Eileen M. Denovan-Wright, Kevin Nash, Alfred S. Lewin and Ronald J. Mandel
Mol Ther 12: 618-633; doi:10.1016/j.ymthe.2005.05.006
Targeting ECM–Integrin Interaction with Liposome-Encapsulated Small Interfering RNAs Inhibits the Growth of Human Prostate Cancer in a Bone Xenograft Imaging Model
Kristen Bisanz, Jie Yu, Magnus Edlund, Bill Spohn, Mien-Chie Hung, Leland W. K. Chung and Chia-Ling Hsieh
Mol Ther 12: 634-643; doi:10.1016/j.ymthe.2005.05.012
Prolonged Recovery of Retinal Structure/Function after Gene Therapy in an Rs1h-Deficient Mouse Model of X-Linked Juvenile Retinoschisis
Seok H. Min, Laurie L. Molday, Mathias W. Seeliger, Astra Dinculescu, Adrian M. Timmers, Andreas Janssen, Felix Tonagel, Naoyuki Tanimoto, Bernhard H. F. Weber, Robert S. Molday and William W. Hauswirth
Mol Ther 12: 644-651; doi:10.1016/j.ymthe.2005.06.002
Amelioration of both Functional and Morphological Abnormalities in the Retina of a Mouse Model of Ocular Albinism Following AAV-Mediated Gene Transfer
Enrico Maria Surace, Luciano Domenici, Katia Cortese, Gabriella Cotugno, Umberto Di Vicino, Consuelo Venturi, Alessandro Cellerino, Valeria Marigo, Carlo Tacchetti, Andrea Ballabio and Alberto Auricchio
Mol Ther 12: 652-658; doi:10.1016/j.ymthe.2005.06.001
Long-term Evaluation of AAV-Mediated sFlt-1 Gene Therapy for Ocular Neovascularization in Mice and Monkeys
Chooi-May Lai, Wei-Yong Shen, Meliha Brankov, Yvonne K.Y. Lai, Nigel L. Barnett, Shu-Yen Lee, Ian Y. S. Yeo, Ranjana Mathur, Joseph E. S. Ho, Paul Pineda, Amutha Barathi, Chong-Lye Ang, Ian J. Constable and Elizabeth P. Rakoczy
Mol Ther 12: 659-668; doi:10.1016/j.ymthe.2005.04.022
Axons mediate the distribution of arylsulfatase a within the mouse hippocampus upon gene delivery
Tonia Luca, Maria I. Givogri, Laura Perani, Francesca Galbiati, Antonia Follenzi, Luigi Naldini and Ernesto R. Bongarzone
Mol Ther 12: 669-679; doi:10.1016/j.ymthe.2005.06.438
Acute Lung Injury with Endotoxin or NO2 Does Not Enhance Development of Airway Epithelium from Bone Marrow
Travis Beckett, Roberto Loi, Robert Prenovitz, Matthew Poynter, Kaarin K. Goncz, Benjamin T. Suratt and Daniel J. Weiss
Mol Ther 12: 680-686; doi:10.1016/j.ymthe.2005.05.007
TRIM5
rh expression restricts HIV-1 infection in lentiviral vector-transduced CD34+-cell-derived macrophages
Joseph Anderson and Ramesh Akkina
Mol Ther 12: 687-696; doi:10.1016/j.ymthe.2005.07.291
T Lymphocytes Transduced with a Lentiviral Vector Expressing F12-vif Are Protected from HIV-1 Infection in an APOBEC3G-Independent Manner
Giuliana Vallanti, Rossella Lupo, Maurizio Federico, Fulvio Mavilio and Chiara Bovolenta
Mol Ther 12: 697-706; doi:10.1016/j.ymthe.2005.05.014
Inhibition of Src Kinase Activity by Ad-mda7 Suppresses Vascular Endothelial Growth Factor Expression in Prostate Carcinoma Cells
Satoshi Inoue, Cynthia D. Branch, Gary E. Gallick, Sunil Chada and Rajagopal Ramesh
Mol Ther 12: 707-715; doi:10.1016/j.ymthe.2005.05.015
Alteration of splicing signals in a genomic/cDNA hybrid VEGF gene to modify the ratio of expressed VEGF isoforms enhances safety of angiogenic gene therapy
Hideki Amano, Neil R. Hackett, Robert J. Kaner, Paul Whitlock, Todd K. Rosengart and Ronald G. Crystal
Mol Ther 12: 716-724; doi:10.1016/j.ymthe.2005.03.031
Specific and efficient transduction of cochlear inner hair cells with recombinant adeno-associated virus type 3 vector
Yuhe Liu, Takashi Okada, Kianoush Sheykholeslami, Kuniko Shimazaki, Tatsuya Nomoto, Shin-Ichi Muramatsu, Takeharu Kanazawa, Koichi Takeuchi, Rahim Ajalli, Hiroaki Mizukami, Akihiro Kume, Keiichi Ichimura and Keiya Ozawa
Mol Ther 12: 725-733; doi:10.1016/j.ymthe.2005.03.021
RNA Transfer by Electroporation into Mature Dendritic Cells Leading to Reactivation of Effector-Memory Cytotoxic T Lymphocytes: A Quantitative Analysis
Miran Javorovic, Heike Pohla, Bernhard Frankenberger, Thomas Wölfel and Dolores J. Schendel
Mol Ther 12: 734-743; doi:10.1016/j.ymthe.2005.03.034
Evidence for Encapsidation of Prokaryotic Sequences during Recombinant Adeno-Associated Virus Production and Their in Vivo Persistence after Vector Delivery
Gilliane Chadeuf, Carine Ciron, Philippe Moullier and Anna Salvetti
Mol Ther 12: 744-753; doi:10.1016/j.ymthe.2005.06.003
Male Germ-Line Cells Are at Risk Following Direct-Injection Retroviral-Mediated Gene Transfer in Utero
Christopher D. Porada, Paul J. Park, Joe Tellez, Ferhat Ozturk, Hudson A. Glimp, Graça Almeida-Porada and Esmail D. Zanjani
Mol Ther 12: 754-762; doi:10.1016/j.ymthe.2005.05.011
Short Communication
Oncogenesis Following Delivery of a Nonprimate Lentiviral Gene Therapy Vector to Fetal and Neonatal Mice
Mike Themis, Simon N. Waddington, Manfred Schmidt, Christof von Kalle, Yoahe Wang, Faisal Al-Allaf, Lisa G. Gregory, Megha Nivsarkar, Matthew Themis, Maxine V. Holder, Suzanne M. K. Buckley, Niraja Dighe, Alaine T. Ruthe, Ajay Mistry, Brian Bigger, Ahad Rahim, Tuan H. Nguyen, Didier Trono, Adrian J. Thrasher and Charles Coutelle
Mol Ther 12: 763-771; doi:10.1016/j.ymthe.2005.07.358
Errata
Erratum to "Enhanced in Vivo Selection of Bone Marrow Cells by Retroviral-Mediated Coexpression of Mutant O 6-Methylguanine-DNA-methyltransferase and HOXB4"
Michael D. Milsom, Lorna B. Woolford, Geoffrey P. Margison, R. Keith Humphries and Leslie J. Fairbairn
Mol Ther 12: 772-773; doi:10.1016/j.ymthe.2004.12.007
