TABLE OF CONTENTS
Volume 12, Issue 3 (September 2005)
Inside This Month |
Research Update |
Conference |
Reviews |
Original Articles |
Short Communication |
Errata
Editorials
Author Feedback Program Reveals Satisfaction with the Review Process at Molecular Therapy
Robert M. Frederickson and David A. Williams
Mol Ther 12: 375-376; doi:10.1016/j.ymthe.2005.07.692
Inside This Month
Top of pageResearch Update
Top of pageConference
Report from the 2nd Stem Cell Clonality and Genotoxicity Retreat
Robert M. Frederickson
Mol Ther 12: 379-383; doi:10.1016/j.ymthe.2005.07.694
Reviews
The Influence of Adenovirus Fiber Structure and Function on Vector Development for Gene Therapy
Stuart A. Nicklin, Eugene Wu, Glen R. Nemerow and Andrew H. Baker
Mol Ther 12: 384-393; doi:10.1016/j.ymthe.2005.05.008
Intrabody Applications in Neurological Disorders: progress and Future Prospects
Todd W. Miller and Anne Messer
Mol Ther 12: 394-401; doi:10.1016/j.ymthe.2005.04.003
Original Articles
Activation of the Extracellular Signal-Regulated Kinase 1/2 Pathway by AAV Gene Transfer Protects Retinal Ganglion Cells in Glaucoma
Yu Zhou, Vincent Pernet, William W. Hauswirth and Adriana Di Polo
Mol Ther 12: 402-412; doi:10.1016/j.ymthe.2005.04.004
AAV2-mediated Ocular Gene Therapy for Infantile Neuronal Ceroid Lipofuscinosis
Megan Griffey, Shannon L. Macauley, Judith M. Ogilvie and Mark S. Sands
Mol Ther 12: 413-421; doi:10.1016/j.ymthe.2005.04.018
AAV2/5 Vector Expressing Galactocerebrosidase Ameliorates CNS Disease in the Murine Model of Globoid-cell Leukodystrophy more Efficiently than AAV2
Darshong Lin, Corinne R. Fantz, Beth Levy, Mohammad A. Rafi, Carole Vogler, David A. Wenger and Mark S. Sands
Mol Ther 12: 422-430; doi:10.1016/j.ymthe.2005.04.019
AAV8-Mediated Hepatic Expression of Acid Sphingomyelinase Corrects the Metabolic Defect in the Visceral Organs of a Mouse Model of Niemann–Pick Disease
Christine M. Barbon, Robin J. Ziegler, Chester Li, Donna Armentano, Maribeth Cherry, Robert J. Desnick, Edward H. Schuchman and Seng H. Cheng
Mol Ther 12: 431-440; doi:10.1016/j.ymthe.2005.03.011
Phenotypic Improvement of Dystrophic Muscles by rAAV/Microdystrophin Vectors Is Augmented by Igf1 Codelivery
Simone Abmayr, Paul Gregorevic, James M. Allen and Jeffrey S. Chamberlain
Mol Ther 12: 441-450; doi:10.1016/j.ymthe.2005.04.001
Type I Interferons Potently Suppress Gene Expression Following Gene Delivery Using Liposome–DNA Complexes
Karen Sellins, Lee Fradkin, Denny Liggitt and Steven Dow
Mol Ther 12: 451-459; doi:10.1016/j.ymthe.2005.04.008
Postmitotic Nuclear Retention of Episomal Plasmids Is Altered by DNA Labeling and Detection Methods
Joshua Z. Gasiorowski and David A. Dean
Mol Ther 12: 460-467; doi:10.1016/j.ymthe.2005.05.001
Role of Clathrin- and Caveolae-Mediated Endocytosis in Gene Transfer Mediated by Lipo- and Polyplexes
Joanna Rejman, Alessandra Bragonzi and Massimo Conese
Mol Ther 12: 468-474; doi:10.1016/j.ymthe.2005.03.038
Plasmid Delivery in Vivo from Porous Tissue-Engineering Scaffolds: Transgene Expression and Cellular Transfection
Jae-Hyung Jang, Christopher B. Rives and Lonnie D. Shea
Mol Ther 12: 475-483; doi:10.1016/j.ymthe.2005.03.036
Factors Influencing Adenovirus-Mediated Airway Transduction in Fetal Mice
S. M. K. Buckley, S. N. Waddington, S. Jezzard, L. Lawrence, H. Schneider, M. V. Holder, M. Themis and C. Coutelle
Mol Ther 12: 484-492; doi:10.1016/j.ymthe.2005.02.020
Aerosolized Nanogram Quantities of Plasmid DNA Mediate Highly Efficient Gene Delivery to Mouse Airway Epithelium
Carsten Rudolph, Ulrike Schillinger, Aurora Ortiz, Christian Plank, Monika M. Golas, Bjoern Sander, Holger Stark and Joseph Rosenecker
Mol Ther 12: 493-501; doi:10.1016/j.ymthe.2005.03.002
Targeting Viral-Mediated Transduction to the Lung Airway Epithelium with the Anti-inflammatory Cationic Lipid Dexamethasone–Spermine
Amber Price, Maria Limberis, Jeffrey A. Gruneich, James M. Wilson and Scott L. Diamond
Mol Ther 12: 502-509; doi:10.1016/j.ymthe.2005.03.033
Targeted Delivery of Oligodeoxynucleotides to Mouse Lung Endothelial Cells in Vitro and in Vivo
Annette Wilson, Wen Zhou, Hunter C. Champion, Sean Alber, Zhi-Lue Tang, Steven Kennel, Simon Watkins, Leaf Huang, Bruce Pitt and Song Li
Mol Ther 12: 510-518; doi:10.1016/j.ymthe.2005.04.005
Localized Gene Expression Following Administration of Adeno-associated Viral Vectors via Pancreatic Ducts
Scott A. Loiler, Qiushi Tang, Tracy Clarke, Martha L. Campbell-Thompson, Vince Chiodo, William Hauswirth, Pedro Cruz, Marcel Perret-Gentil, Mark A. Atkinson, Vijayakumar K. Ramiya and Terence R. Flotte
Mol Ther 12: 519-527; doi:10.1016/j.ymthe.2005.04.017
Evaluation of Viral and Mammalian Promoters for Use in Gene Delivery to Salivary Glands
Changyu Zheng and Bruce J. Baum
Mol Ther 12: 528-536; doi:10.1016/j.ymthe.2005.03.008
Comparison of HIV- and EIAV-Based Vectors on Their Efficiency in Transducing Murine and Human Hematopoietic Repopulating Cells
Elena K. Siapati, Brian W. Bigger, James Miskin, Daniel Chipchase, Kathryn L. Parsley, Kyriacos Mitrophanous, Mike Themis, Adrian J. Thrasher and Dominique Bonnet
Mol Ther 12: 537-546; doi:10.1016/j.ymthe.2005.01.022
Efficient Gene Transfer into Mouse Embryonic Stem Cells with Adenovirus Vectors
Kenji Kawabata, Fuminori Sakurai, Teruhide Yamaguchi, Takao Hayakawa and Hiroyuki Mizuguchi
Mol Ther 12: 547-554; doi:10.1016/j.ymthe.2005.04.015
Toward a Gene Therapy for Dominant Disease: Validation of an RNA Interference-Based Mutation-Independent Approach
Anna-Sophia Kiang, Arpad Palfi, Marius Ader, Paul F. Kenna, Sophia Millington-Ward, Gerry Clark, Avril Kennan, Mary O'Reilly, Lawrence C. T. Tam, Aileen Aherne, Niamh McNally, Pete Humphries and G. Jane Farrar
Mol Ther 12: 555-561; doi:10.1016/j.ymthe.2005.03.028
Short Communication
Small Hairpin RNAs Efficiently Inhibit Hepatitis C IRES–Mediated Gene Expression in Human Tissue Culture Cells and a Mouse Model
Qian Wang, Christopher H. Contag, Heini Ilves, Brian H. Johnston and Roger L. Kaspar
Mol Ther 12: 562-568; doi:10.1016/j.ymthe.2005.04.014
A picornaviral 2A-like Sequence-based Tricistronic Vector Allowing for High-level Therapeutic Gene Expression Coupled to a Dual-Reporter System
Mark J. Osborn, Angela Panoskaltsis-Mortari, Ron T. McElmurry, Scott K. Bell, Dario A. A. Vignali, Martin D. Ryan, Andrew C. Wilber, R. Scott McIvor, Jakub Tolar and Bruce R. Blazar
Mol Ther 12: 569-574; doi:10.1016/j.ymthe.2005.04.013
Enhanced Efficacy of Cholesterol-Minus Sonic Hedgehog in Postnatal Skin
Howard Lou, Ronald G. Crystal and Philip L. Leopold
Mol Ther 12: 575-578; doi:10.1016/j.ymthe.2005.01.009
Errata
Erratum to "Sustained Phenotypic Correction of Hemophilia A Mice Following Oncoretroviral-Mediated Expression of a Bioengineered Human Factor VIII Gene in Long-Term Hematopoietic Repopulating Cells"
Morvarid Moayer, Ali Ramezani, Richard A. Morgan, Teresa S. Hawley and Robert G. Hawley
Mol Ther 12: 579-580; doi:10.1016/j.ymthe.2004.08.006
