TABLE OF CONTENTS
Volume 12, Issue 1 (July 2005)
Inside this Month |
Research Update |
Conference |
Reviews |
Original Article |
Short communication
Editorial
Clinical Application of Gene Transfer Technology: Overcoming the Obstacles
Theodore Freidmann
Mol Ther 12: 1-2; doi:10.1016/j.ymthe.2005.05.002
Inside this Month
Top of pageResearch Update
Top of pageConference
Critical Path Workshop on the Development of Cellular and Gene Therapy Products
Eda T. Bloom, Suzanne L. Epstein and Stephanie L. Simek
Mol Ther 12: 5-8; doi:10.1016/j.ymthe.2005.05.004
Reviews
Gene Targeting with Viral Vectors
Paul C. Hendrie and David W. Russell
Mol Ther 12: 9-17; doi:10.1016/j.ymthe.2005.04.006
GM-CSF Gene-Transduced Tumor Vaccines
Robert Eager and John Nemunaitis
Mol Ther 12: 18-27; doi:10.1016/j.ymthe.2005.02.012
Original Article
Cellular Manipulation of Human Embryonic Stem Cells by TAT-PDX1 Protein Transduction
Young Do Kwon, Sun Kyung Oh, Hee Sun Kim, Seung-Yup Ku, Seok Hyun Kim, Young Min Choi and Shin Yong Moon
Mol Ther 12: 28-32; doi:10.1016/j.ymthe.2005.03.010
High-Resolution Imaging of Bone Precursor Cells Within the Intact Bone Marrow Cavity of Living Mice
Philipp Mayer-Kuckuk, Terence P. F. Gade, Ian M. Buchanan, Mikhail Doubrovin, Ludmilla Ageyeva, Joseph R. Bertino, Adele L. Boskey, Ronald G. Blasberg, Jason A. Koutcher and Debabrata Banerjee
Mol Ther 12: 33-41; doi:10.1016/j.ymthe.2005.02.018
Real-Time in Vivo Imaging of Stem Cells Following Transgenesis by Transposition
Jakub Tolar, Mark Osborn, Scott Bell, Ron McElmurry, Lily Xia, Megan Riddle, Angela Panoskaltsis-Mortari, Yuehua Jiang, R. Scott McIvor, Christopher H. Contag, Stephen R. Yant, Mark A. Kay, Catherine M. Verfaillie and Bruce R. Blazar
Mol Ther 12: 42-48; doi:10.1016/j.ymthe.2005.02.023
Noninvasive Imaging of ex Vivo Intracoronarily Delivered Nonviral Therapeutic Transgene Expression in Heart
Luyi Sen, Sanjiv S. Gambhir, Hiroshi Furukawa, David B. Stout, Allison Linh Lam, Hillel Laks and Guanggen Cui
Mol Ther 12: 49-57; doi:10.1016/j.ymthe.2005.03.004
Hepatocyte Growth Factor Gene Transfer to Alveolar Septa for Effective Suppression of Lung Fibrosis
Masaki Watanabe, Masahito Ebina, Frank M. Orson, Akira Nakamura, Kazuo Kubota, Daizo Koinuma, Ken-ichi Akiyama, Makoto Maemondo, Shinya Okouchi, Minoru Tahara, Kunio Matsumoto, Toshikazu Nakamura and Toshihiro Nukiwa
Mol Ther 12: 58-67; doi:10.1016/j.ymthe.2005.02.019
IFN-
gene therapy for woodchuck hepatitis with adeno-associated virus: differences in duration of gene expression and antiviral activity using intraportal or intramuscular routes
Pedro Berraondo, Laura Ochoa, Julien Crettaz, Fernando Rotellar, África Vales, Eduardo Martínez-Ansó, Mikel Zaratiegui, Juan Ruiz, Gloria González-Aseguinolaza and Jesús Prieto
Mol Ther 12: 68-76; doi:10.1016/j.ymthe.2005.02.017
Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34+ cells
Greg M. Podsakoff, Barbara C. Engel, Denise A. Carbonaro, Chris Choi, Elzbieta M. Smogorzewska, Gerhard Bauer, David Selander, Susan Csik, Kathy Wilson, Michael R. Betts, Richard A. Koup, Gary J. Nabel, Keith Bishop, Steven King, Manfred Schmidt, Christof von Kalle, Joseph A. Church and Donald B. Kohn
Mol Ther 12: 77-86; doi:10.1016/j.ymthe.2005.02.024
Intrapulmonary and intramyocardial gene transfer in rhesus monkeys (Macaca mulatta): Safety and efficiency of HIV-1-derived lentiviral vectors for fetal gene delivery
Alice F. Tarantal, Ruth J. McDonald, Daniel F. Jimenez, C. Chang I. Lee, Cristin E. O'Shea, Alyssa C. Leapley, Rosa H. Won, Charles G. Plopper, Carolyn Lutzko and Donald B. Kohn
Mol Ther 12: 87-98; doi:10.1016/j.ymthe.2005.01.019
Increased Hepatic Transduction with Reduced Systemic Dissemination and Proinflammatory Cytokines Following Hydrodynamic Injection of Helper-Dependent Adenoviral Vectors
Nicola Brunetti-Pierri, Donna J. Palmer, Viraj Mane, Milton Finegold, Arthur L. Beaudet and Philip Ng
Mol Ther 12: 99-106; doi:10.1016/j.ymthe.2005.03.001
Combined Genetic and Chemical Capsid Modifications Enable Flexible and Efficient De- and Retargeting of Adenovirus Vectors
Florian Kreppel, Judith Gackowski, Erika Schmidt and Stefan Kochanek
Mol Ther 12: 107-117; doi:10.1016/j.ymthe.2005.03.006
Development of a transposon-based approach for identifying novel transgene insertion sites within the replicating adenovirus
Peter J. Kretschmer, Fang Jin, Cecile Chartier and Terry W. Hermiston
Mol Ther 12: 118-127; doi:10.1016/j.ymthe.2005.03.019
Endogenously Expressed Multimeric Self-Cleaving Hammerhead Ribozymes Ablate Mutant Collagen in Cellulo
Belinda E. Peace, Jane B. Florer, David Witte, Yoel Smicun, Iva Toudjarska, George Wu, Michael W. Kilpatrick, Petros Tsipouras and Richard J. Wenstrup
Mol Ther 12: 128-136; doi:10.1016/j.ymthe.2005.02.015
Prolonged transgene expression in murine salivary glands following non-primate lentiviral vector transduction
Ela Shai, Aaron Palmon, Amos Panet, Yitzhak Marmary, Yoav Sherman, Michael A. Curran, Eithan Galun and Reba Condiotti
Mol Ther 12: 137-143; doi:10.1016/j.ymthe.2005.02.022
A microarray study to characterize the molecular mechanism of TIMP-3-mediated tumor rejection
Paula Lam, Kar Sian Lim, Suk Mei Wang and Kam M. Hui
Mol Ther 12: 144-152; doi:10.1016/j.ymthe.2005.02.028
Semliki Forest Virus Vectors Engineered to Express Higher IL-12 Levels Induce Efficient Elimination of Murine Colon Adenocarcinomas
Juan R. Rodriguez-Madoz, Jesus Prieto and Cristian Smerdou
Mol Ther 12: 153-163; doi:10.1016/j.ymthe.2005.02.011
–Amino Ester Polymers Facilitate in Vivo DNA Transfection and Adjuvant Plasmid DNA Immunization
John R. Greenland, Huining Liu, David Berry, Daniel G. Anderson, Woong–Ki Kim, Darrell J. Irvine, Robert Langer and Norman L. Letvin
Mol Ther 12: 164-170; doi:10.1016/j.ymthe.2005.01.021
Identification of factors that contribute to recombinant AAV2 particle aggregation and methods to prevent its occurrence during vector purification and formulation
J. Fraser Wright, Tannie Le, Joseph Prado, Jennifer Bahr-Davidson, Peter H. Smith, Zhu Zhen, Jurg M. Sommer, Glenn F. Pierce and Guang Qu
Mol Ther 12: 171-178; doi:10.1016/j.ymthe.2005.02.021
