TABLE OF CONTENTS

Volume 11, Issue 6 (June 2005)

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Editorial

A Balanced Decision? Regulatory Reaction to the "Third Case"

David A. Williams

Mol Ther 11: 819-820; doi:10.1016/j.ymthe.2005.04.010

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Inside this month

Inside this Month

Mol Ther 11: 821; doi:10.1016/j.ymthe.2005.04.011

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Research Updates

Research Update

Mol Ther 11: 822; doi:10.1016/j.ymthe.2005.04.012

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Review

Current status of gene therapy strategies to treat HIV/AIDS

David S. Strayer, Ramesh Akkina, Bruce A. Bunnell, Boro Dropulic, Vicente Planelles, Roger J. Pomerantz, John J. Rossi and John A. Zaia

Mol Ther 11: 823-842; doi:10.1016/j.ymthe.2005.01.020

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Original Articles

Adeno-associated virus-mediated gene transfer to hair cells and support cells of the murine cochlea

Ida M. Stone, Diana I. Lurie, Mathew W. Kelley and David J. Poulsen

Mol Ther 11: 843-848; doi:10.1016/j.ymthe.2005.02.005

A Novel Bovine Virus Efficiently Transduces Inner Ear Neuroepithelial Cells

Giovanni Di Pasquale, Agnieszka Rzadzinska, Mark E. Schneider, Ioannis Bossis, John A. Chiorini and Bechara Kachar

Mol Ther 11: 849-855; doi:10.1016/j.ymthe.2005.02.004

Altering AAV tropism with mosaic viral capsids

Laure Gigout, Patricia Rebollo, Nathalie Clement, Kenneth H. Warrington Jr., Nicholas Muzyczka, R. Michael Linden and Thomas Weber

Mol Ther 11: 856-865; doi:10.1016/j.ymthe.2005.03.005

Genetic analysis of the antibody response to AAV2 and factor IX

Huang-Ge Zhang, Katherine A. High, Qi Wu, PingAr Yang, Alex Schlachterman, Shaohua Yu, Nengjun Yi, Hui-Chen Hsu and John D. Mountz

Mol Ther 11: 866-874; doi:10.1016/j.ymthe.2005.02.014

Comparison of the ability of adeno-associated viral vectors pseudotyped with serotype 2, 5, and 8 capsid proteins to mediate efficient transduction of the liver in murine and nonhuman primate models

Andrew M. Davidoff, John T. Gray, Catherine Y.C. Ng, Youbin Zhang, Junfang Zhou, Yunyu Spence, Yusura Bakar and Amit C. Nathwani

Mol Ther 11: 875-888; doi:10.1016/j.ymthe.2004.12.022

Correction of glycogen storage disease type II by an adeno-associated virus vector containing a muscle-specific promoter

Baodong Sun, Haoyue Zhang, Luis M. Franco, Talmage Brown, Andrew Bird, Ayn Schneider and Dwight D. Koeberl

Mol Ther 11: 889-898; doi:10.1016/j.ymthe.2005.01.012

In vivo Inhibition of Hippocampal Ca2+/Calmodulin-Dependent Protein Kinase II by RNA Interference

A. M. Babcock, D. Standing, K. Bullshields, E. Schwartz, C. M. Paden and D. J. Poulsen

Mol Ther 11: 899-905; doi:10.1016/j.ymthe.2005.02.016

Lentiviral-mediated transfer of CNTF to schwann cells within reconstructed peripheral nerve grafts enhances adult retinal ganglion cell survival and axonal regeneration

Ying Hu, Simone G. Leaver, Giles W. Plant, William T. J. Hendriks, Simone P. Niclou, Joost Verhaagen, Alan R. Harvey and Qi Cui

Mol Ther 11: 906-915; doi:10.1016/j.ymthe.2005.01.016

Regulated lentiviral NGF gene transfer controls rescue of medial septal cholinergic neurons

Armin Blesch, James Conner, Alexander Pfeifer, Mehdi Gasmi, Anthony Ramirez, William Britton, Ron Alfa, Inder Verma and Mark H. Tuszynski

Mol Ther 11: 916-925; doi:10.1016/j.ymthe.2005.01.007

In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis

Khalid Shah, Ching-Hsuan Tung, Xandra O. Breakefield and Ralph Weissleder

Mol Ther 11: 926-931; doi:10.1016/j.ymthe.2005.01.017

Efficiency of transduction of highly purified murine hematopoietic stem cells by lentiviral and oncoretroviral vectors under conditions of minimal in vitro manipulation

Gustavo Mostoslavsky, Darrell N. Kotton, Attila J. Fabian, John T. Gray, Jeng-Shin Lee and Richard C. Mulligan

Mol Ther 11: 932-940; doi:10.1016/j.ymthe.2005.01.005

Enhanced immunity by NeuEDhsp70 DNA vaccine Is needed to combat an aggressive spontaneous metastatic breast cancer

Jin H. Kim, Nilanjana Majumder, Honghui Lin, Janet Chen, Louis D. Falo Jr. and Zhaoyang You

Mol Ther 11: 941-949; doi:10.1016/j.ymthe.2005.01.003

Induction of leukemia-specific CD8+ cytotoxic t cells with autologous myeloid leukemic cells maturated with a fiber-modified adenovirus encoding TNF-alpha

Aurore Saudemont, Selim Corm, Thomas Wickham, Dominique Hetuin and Bruno Quesnel

Mol Ther 11: 950-959; doi:10.1016/j.ymthe.2004.12.016

Vaccination with the recombinant allergen ProDer p 1 complexed with the cationic lipid DiC14-amidine prevents allergic responses to house dust mite

Alain Jacquet, Jean-François Vanderschrick, Michel Vandenbranden, Abdelatif Elouahabi, Mauro Magi, Lida Garcia and Jean-Marie Ruysschaert

Mol Ther 11: 960-968; doi:10.1016/j.ymthe.2004.12.024

Efficient Gene Transfer to Human Epidermal Keratinocytes on Fibronectin: In Vitro Evidence for Transduction of Epidermal Stem Cells

Bharat G. Bajaj, Pedro Lei and Stelios T. Andreadis

Mol Ther 11: 969-979; doi:10.1016/j.ymthe.2004.10.023

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Short Communications

Widespread and early myocardial gene expression by adeno-associated virus vector type 6 with a beta-actin hybrid promoter

Shunsuke Kawamoto, Qun Shi, Yoshio Nitta, Jun-ichi Miyazaki and Margaret D. Allen

Mol Ther 11: 980-985; doi:10.1016/j.ymthe.2005.02.009

Development of Pegylated Forms of Recombinant Rhodosporidium toruloides Phenylalanine Ammonia-Lyase for the Treatment of Classical Phenylketonuria

Alejandra Gámez, Christineh N. Sarkissian, Lin Wang, Woomi Kim, Mary Straub, Marianne G. Patch, Lin Chen, Steve Striepeke, Paul Fitzpatrick, Jeffrey F. Lemontt, Charles O'Neill, Charles R. Scriver and Raymond C. Stevens

Mol Ther 11: 986-989; doi:10.1016/j.ymthe.2005.02.013

A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy

S. Moein Moghimi, Peter Symonds, J. Clifford Murray, A. Christy Hunter, Grazyna Debska and Adam Szewczyk

Mol Ther 11: 990-995; doi:10.1016/j.ymthe.2005.02.010

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