Molecular Therapy

FIGURE 2

FROM:

A Novel Bovine Virus Efficiently Transduces Inner Ear Neuroepithelial Cells

Giovanni Di Pasquale, Agnieszka Rzadzinska, Mark E. Schneider, Ioannis Bossis, John A. Chiorini and Bechara Kachar

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Figure 2.

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Comparison of transduction. Cells were transduced with increasing viral titers (109 to 1011 DRP/ml) of BAAV and analyzed after 8 days. Transduction increased significantly for outer hair cells (OHC; n = 5 and 13, respectively; single-factor ANOVA, P = 0.01699) and vestibular hair cells (VHC; n = 6 and 10, respectively; single-factor ANOVA, P = 0.000168), with a 100-fold increase in viral titer after 8 days of infection. The differences in transduction yield of inner hair cells (IHC) were not significant (n = 5 and 1, respectively; single-factor ANOVA, P = 0.23987). (Error bars represent SD.)

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