TABLE OF CONTENTS

Volume 11, Issue 5 (May 2005)

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Editorial

Helping RNAi Deliver

John Rossi

Mol Ther 11: 653; doi:10.1016/j.ymthe.2005.03.013

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Inside this month

Inside this month

Mol Ther 11: 654; doi:10.1016/j.ymthe.2005.03.016

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Research update

Research update

Mol Ther 11: 655; doi:10.1016/j.ymthe.2005.03.015

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Conference

From crystal structure to clinic: Highlights of the tenth international parvovirus workshop

Aravind Asokan and Richard J. Samulski

Mol Ther 11: 656-660; doi:10.1016/j.ymthe.2005.03.014

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Review

In Utero gene therapy: current challenges and perspectives

Simon N. Waddington, M. Gabriela Kramer, Ruben Hernandez-Alcoceba, Suzanne M.K. Buckley, Michael Themis, Charles Coutelle and Jesus Prieto

Mol Ther 11: 661-676; doi:10.1016/j.ymthe.2005.01.015

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Original Articles

Aptamers directed to HIV-1 reverse transcriptase display greater efficacy over small hairpin RNAs targeted to viral RNA in blocking HIV-1 replication

Pheroze J. Joshi, Thomas W. North and Vinayaka R. Prasad

Mol Ther 11: 677-686; doi:10.1016/j.ymthe.2005.01.013

Retargeting mobile group II introns to repair mutant genes

John Patrick Jones III, Monique N. Kierlin, Robert G. Coon, Jiri Perutka, Alan M. Lambowitz and Bruce A. Sullenger

Mol Ther 11: 687-694; doi:10.1016/j.ymthe.2005.01.014

A Direct Comparison of Two Nonviral Gene Therapy Vectors for Somatic Integration: In Vivo Evaluation of the Bacteriophage Integrase phiC31 and the Sleeping Beauty Transposase

Anja Ehrhardt, Hui Xu, Zan Huang, Jeffrey A. Engler and Mark A. Kay

Mol Ther 11: 695-706; doi:10.1016/j.ymthe.2005.01.010

Systemic administration of attenuated Salmonella choleraesuis in combination with cisplatin for cancer therapy

Che-Hsin Lee, Chao-Liang Wu, Yun-Sheng Tai and Ai-Li Shiau

Mol Ther 11: 707-716; doi:10.1016/j.ymthe.2005.01.008

mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: Identification of IL-20 receptor-mediated bystander activity against pancreatic cancer

Sunil Chada, Dora Bocangel, Rajagopal Ramesh, Elizabeth A. Grimm, John B. Mumm, Abner M. Mhashilkar and Mingzhong Zheng

Mol Ther 11: 724-733; doi:10.1016/j.ymthe.2004.12.021

AAV-Mediated expression of galactocerebrosidase in brain results in attenuated symptoms and extended life span in murine models of globoid cell leukodystrophy

Mohammad A. Rafi, Han Zhi Rao, Marco A. Passini, Mark Curtis, Marie T. Vanier, Mariam Zaka, Paola Luzi, John H. Wolfe and David A. Wenger

Mol Ther 11: 734-744; doi:10.1016/j.ymthe.2004.12.020

Restoration of Aspartoacylase Activity in CNS Neurons Does Not Ameliorate Motor Deficits and Demyelination in a Model of Canavan Disease

Matthias Klugmann, Claudia B. Leichtlein, C. Wymond Symes, Tadao Serikawa, Deborah Young and Matthew J. During

Mol Ther 11: 745-753; doi:10.1016/j.ymthe.2005.01.006

AAV Vector-Mediated Correction of Brain Pathology in a Mouse Model of Niemann–Pick A Disease

Marco A. Passini, Shannon L. Macauley, Michael R. Huff, and Tatyana V. Taksir, Jie Bu, I-Huan Wu, Peter A. Piepenhagen, James C. Dodge, Lamya S. Shihabuddin, Catherine R. O'Riordan, Edward H. Schuchman and Gregory R. Stewart

Mol Ther 11: 754-762; doi:10.1016/j.ymthe.2005.01.011

Efficient Tet-Dependent Expression of Human Factor IX in Vivo by a New Self-Regulating Lentiviral Vector

Elisa Vigna, Mario Amendola, Fabrizio Benedicenti, Andrew D. Simmons, Antonia Follenzi and Luigi Naldini

Mol Ther 11: 763-775; doi:10.1016/j.ymthe.2004.11.017

Neonatal Gene Therapy of MPS I Mice by Intravenous Injection of a Lentiviral Vector

Hiroshi Kobayashi, Denise Carbonaro, Karen Pepper, Denise Petersen, Shundi Ge, Holly Jackson, Hiroyuki Shimada, Rex Moats and Donald B. Kohn

Mol Ther 11: 776-789; doi:10.1016/j.ymthe.2004.10.006

Immunolipoplexes: An Efficient, Nonviral Alternative for Transfection of Human Dendritic Cells with Potential for Clinical Vaccination

Peng H. Tan, Sven C. Beutelspacher, Yao-He Wang, Myra O. McClure, Mary A. Ritter, Giovanna Lombardi and Andrew J. T. George

Mol Ther 11: 790-800; doi:10.1016/j.ymthe.2004.12.009

Nonbilayer phase of lipoplex–membrane mixture determines endosomal escape of genetic cargo and transfection efficiency

Inge S. Zuhorn, Udo Bakowsky, Evgeny Polushkin, Willy H. Visser, Marc C.A. Stuart, Jan B.F.N. Engberts and Dick Hoekstra

Mol Ther 11: 801-810; doi:10.1016/j.ymthe.2004.12.018

Amplification of RNAi—Targeting HLA mRNAs

Sergio Gonzalez, Daniela Castanotto, and Haitang Li, Simon Olivares, Michael C. Jensen, Stephen J. Forman, John J. Rossi and Laurence J.N. Cooper

Mol Ther 11: 811-818; doi:10.1016/j.ymthe.2004.12.023

Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR

Abujiang Pataer, Stephan A. Vorburger, Sunil Chada, Siddharth Balachandran, Glen N. Barber, Jack A. Roth, Kelly K. Hunt and Stephen G. Swisher

Mol Ther 11: 717-723; doi:10.1016/j.ymthe.2005.01.018

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