TABLE OF CONTENTS
Volume 11, Issue S1 (May 2005)
Abstracts
1. Persistent Gene Expression in Mouse Nasal Epithelia Following Baculovirus GP64 Pseudotyped FIV-Based Gene Transfer
Patrick L. Sinn, Erin R. Burnight, Melissa A. Hickey, Gary W. Blissard and Paul B. McCray Jr
Mol Ther 11: S1-S1; doi:10.1016/j.ymthe.2005.06.004
2. Cellular Mechanisms Involved with Lentiviral Gene Transfer
Shangming Zhang, Karen Pollok, Lakshmi Sastry, Lionel Berthoux, Jeremy Luban and Kenneth Cornetta
Mol Ther 11: S1-S1; doi:10.1016/j.ymthe.2005.06.005
3. Effects of the cHS4 Insulator Elements on Transgene Expression and Biological Titer of Lentiviral Vector
Hideki Hanawa and Takashi Shimada
Mol Ther 11: S1-S2; doi:10.1016/j.ymthe.2005.06.006
4. Optimization of Globin Lentiviral Vector Design for the Treatment of |[beta]|-Thalassemia
Leszek Lisowski, Stefano Rivella and Michel Sadelain
Mol Ther 11: S2-S2; doi:10.1016/j.ymthe.2005.06.007
5. Differential Expression of PIT1 and PIT2 after G-CSF Mobilization Is Associated with Efficient Gene Transfer Using GALV-Pseudotyped Gammaretroviral Vectors
Brian C. Beard, Pau Mezquita, Julia C. Morris and Hans-Peter Kiem
Mol Ther 11: S2-S3; doi:10.1016/j.ymthe.2005.06.008
6. In Vivo Adult Stem Cell Gene Transfer in Mice by In Situ Delivery of a Self-Inactivating Lentiviral Vector Using Intrafemoral Injection
D. Nicole Worsham, Kimberly Bohn, David Kuhel, David A. Williams, Christof von Kalle and Dao Pan
Mol Ther 11: S3-S3; doi:10.1016/j.ymthe.2005.06.009
7. Transduction of Quiescent Human Cells Using an SIVsmmPBj-Derived Lentiviral Vector
Matthias Schweizer, Nina Wolfrum, Michael Muehlebach, Julia Kaiser, Silke Schuele and Klaus Cichutek
Mol Ther 11: S3-S3; doi:10.1016/j.ymthe.2005.06.010
8. Potent Inhibition of HIV-1 Replication by Lentiviral Vectors Carrying Anti-Vif siRNA
S. Li, G. Wang, K. Meinking, M. J. Li, J. Ji, J. A. Zaia and J. J. Rossi
Mol Ther 11: S3-S4; doi:10.1016/j.ymthe.2005.06.011
9. Coronaviruses: Development of Novel Oncolytic Vectors
Tom W|[uuml]|rdinger, H|[eacute]|l|[egrave]|ne M. Verheije, Victor W. van Beusechem, Xander A. M. de Haan, Winald R. Gerritsen and Peter J. M. Rottier
Mol Ther 11: S4-S4; doi:10.1016/j.ymthe.2005.06.012
10. The Effect of Globin Locus Control Region (LCR) Elements or the MSCV-LTR on Promoter Trapping by Integrated Lentiviral Vector Genomes
Byoung Y. Ryu, Derek A. Persons and Arthur W. Nienhuis
Mol Ther 11: S4-S4; doi:10.1016/j.ymthe.2005.06.013
11. An Additional Role of Cellular FKBP52 in Recombinant Adeno-Associated Virus 2 Vector-Mediated Gene Transfer and Transgene Expression
Weihong Zhao, Li Zhong, Jianqing Wu, Liyuan Chen, Keyun Qing, Kirsten A. Weigek-Kelley, Steven H. Larsen and Arun Srivastava
Mol Ther 11: S5-S5; doi:10.1016/j.ymthe.2005.06.014
12. Self-Complementary AAV2 Vectors Transduce Liver with the Same Efficiency as AAV8: The Critical Role of Second-Strand Synthesis in AAV Biology
Zhijian Wu, Hongzhe Duan and R. Jude Samulski
Mol Ther 11: S5-S5; doi:10.1016/j.ymthe.2005.06.015
13. Persistence of AAV Capsid in Transduced Cells
Mo-Ying Hsieh, Fayaz R. Khazi, Alexander Schlachterman, Yi-Lin Liu and Katherine A. High
Mol Ther 11: S5-S6; doi:10.1016/j.ymthe.2005.06.016
14. rAAV2 Integration Junctions Isolated without In Vivo Selection Bias Show a Preference to 5|[prime]| Regions of Open Reading Frames
Fayaz R. Khazi, Alexander Schlachterman and Katherine A. High
Mol Ther 11: S6-S6; doi:10.1016/j.ymthe.2005.06.017
15. Large-Scale Analysis of Adeno-Associated Virus Vector Integration Sites in Normal Human Cells
Daniel G. Miller, Grant D. Trobridge, Lisa M. Petek, Michael A. Jacobs, Rajinder Kaul and David W. Russell
Mol Ther 11: S6-S6; doi:10.1016/j.ymthe.2005.06.018
16. Single-Polarity Recombinant Adeno-Associated Virus 2 Vector-Mediated Transgene Expression In Vitro and In Vivo: Mechanism of Transduction
Li Zhong, Xiaohuai Zhou, Yanjun Li, Keyun Qing, Richard J. Samulski and Arun Srivastava
Mol Ther 11: S7-S7; doi:10.1016/j.ymthe.2005.06.019
17. Visualization of the Intranuclear rAAV Replication Centers and Their Co-Localization with Double-Stranded DNA Break Repair Proteins
Cervelli Tiziana, Lorena Zentilin, Alessandro Marcello and Mauro Giacca
Mol Ther 11: S7-S7; doi:10.1016/j.ymthe.2005.06.020
18. Facilitation of AAV Genome Circularization by Host Cell Factors Involved in DNA Replication and Double-Strand Break Repair
Vivian W. Choi, Douglas M. McCarty and Richard J. Samulski
Mol Ther 11: S8-S8; doi:10.1016/j.ymthe.2005.06.021
19. rAAV-2 Transduction of Primitive Human Hematopoietic Stem Cells Capable of Serial Engraftment in Immune Deficient Mice
Helicia Paz, Leah Santat, Lijing Li, Christie Wong, Stephen J. Forman, K.K. Wong and Saswati Chatterjee
Mol Ther 11: S8-S8; doi:10.1016/j.ymthe.2005.06.022
20. Targeted Gene Delivery to Embryonic Stem Cells
Els Henckaerts, Nadja Zeltner, Steven Kattman, Nathalie Dutheil, Peter Ward, Marion Kennedy, Nathalie Clement, Patricia Rebollo, Gordon Keller and R. Michael Linden
Mol Ther 11: S8-S9; doi:10.1016/j.ymthe.2005.06.023
21. Application of Splice Acceptor Transposons to the Development of Oncolytic Viruses
Fang Jin, Peter Kretschmer, Cecile Chartier, Irene Kuhn and Terry Hermiston
Mol Ther 11: S9-S9; doi:10.1016/j.ymthe.2005.06.024
22. Generation of Circular Sleeping Beauty DNA Transposition Substrates by RU486-Induced Flp Recombination In Vitro |[ndash]| Steps towards a Single Integrating Adeno-Transposon Vector
Jacob G. Mikkelsen, Stephen R. Yant, Anja Ehrhardt and Mark A. Kay
Mol Ther 11: S9-S9; doi:10.1016/j.ymthe.2005.06.025
23. Frequency of Random and Targeted Chromosomal Integration of Helper-Dependent Adenoviral Vector
Fumi Ohbayashi, Emi Aizawa, Atshuhiro Kishimoto and Ko Mitani
Mol Ther 11: S9-S10; doi:10.1016/j.ymthe.2005.06.026
24. Context-Specific Peptide-Presenting Phage Libraries for Adenoviral Vector Targeting
Debadyuti Ghosh and Michael A. Barry
Mol Ther 11: S10-S10; doi:10.1016/j.ymthe.2005.06.027
25. Genetic Incorporation of HSV-1 Thymidine Kinase into the Adenovirus Protein IX for Functional Display on the Virion
Jing Li, Long Le, Don A. Sibley, J. Michael Mathis and David T. Curiel
Mol Ther 11: S10-S10; doi:10.1016/j.ymthe.2005.06.028
26. Microsphere Delivery of Adenoviral-Liposome Complexes Reduces Adenoviral Immunogenicity and Allows Successful Re-Administration of the Virus without Loss of Gene Expression Efficiency
Jason C. Steel, John C. Morris, Mark A. Burton, Heather M.A. Cavanagh and Wouter H.J. Kalle
Mol Ther 11: S11-S11; doi:10.1016/j.ymthe.2005.06.029
27. A Novel |[ldquo]|Geneti-Chemical|[rdquo]| Platform for Flexible and Efficient De- and Retargeting of Adenovirus Vector Particles
Florian Kreppel, Judith Gackowski, Erika Schmidt and Stefan Kochanek
Mol Ther 11: S11-S11; doi:10.1016/j.ymthe.2005.06.030
28. Adenovirus Targeting Via Leucine Zipper Peptide-Mediated Ligand Attachment
Joel N. Glasgow, Nikolay Korokhov and David T. Curiel
Mol Ther 11: S11-S12; doi:10.1016/j.ymthe.2005.06.040
29. Redirection of Adenoviral Tropism through Capsomers Other Than Fiber Is Generally Inefficient and Dependent on Ligand-Receptor Biology
Samuel K. Campos and Michael A. Barry
Mol Ther 11: S12-S12; doi:10.1016/j.ymthe.2005.06.031
30. AdenoLibrary for Construction and Selection of Targeted Adenoviruses
Sam C. Noureddini, Alexander Krendelshchikov, Vera Simonenko, Joanne T. Douglas, David T. Curiel and Nikolay Korokhov
Mol Ther 11: S12-S12; doi:10.1016/j.ymthe.2005.06.032
31. Somatic Gene Therapy for ADA-SCID Following Cessation of PEG-ADA and Use of a Mild Conditioning Regime
Hubert B. Gaspar, Emma Bjorkegren, Katherine Parsley, Kimberly C. Gilmour, Jo Sinclair, Fang Zhang, Lynette D. Fairbanks, Doug King, Graham Davies, Paul A. Veys, Christine Kinnon and Adrian J. Thrasher
Mol Ther 11: S13-S13; doi:10.1016/j.ymthe.2005.06.041
32. Tolerance after Neonatal Gene Transfer of a Human Factor IX-Expressing Retroviral Vector May Involve Clonal Deletion in C3H Mice and Is Effective in Hemophilia B Dogs
Lingfei Xu, Mark E. Haskins, Timothy C. Nichols, Manxue Mei, Patty O'Donnell, Dwight A. Bellinger, Stephanie McCorquodale and Katherine P. Ponder
Mol Ther 11: S13-S13; doi:10.1016/j.ymthe.2005.06.033
33. Non-Random Genomic Distribution of Retrovirus Vector Integration in Successful SCID-X1 Gene Therapy
Kerstin Schwarzwaelder, Manfred Schmidt, Steven Howe, Hanno Glimm, Claudia Prinz, Manuela Wissler, Annette Deichmann, Sonja Schmidt, Bobby Gaspar, Adrian Thrasher and Christof von Kalle
Mol Ther 11: S14-S14; doi:10.1016/j.ymthe.2005.06.034
34. Transposon-Based Gene Therapy of Hemophilia A Targeting Endothelial Cells in Neonates
Li Liu and Bradley S. Fletcher
Mol Ther 11: S14-S14; doi:10.1016/j.ymthe.2005.06.035
35. Generalized Detoxification Associated with Engraftment of Gene-Corrected Repopulating Cells Achieved in ADA-SCID Patients by Stem Cell Gene Therapy without Myelopreparative Pre-Conditioning
Makoto Otsu, Satoru Nakajima, Miyuki Kida, Yoshihiro Maeyama, Nariaki Toita, Norikazu Hatano, Nobuaki Kawamura, Motohiko Okano, Ryouji Kobayashi, Osamu Tatsuzawa, Masafumi Onodera, Fabio Candotti, Michael S. Hershfield, Yukio Sakiyama and Tadashi Ariga
Mol Ther 11: S14-S15; doi:10.1016/j.ymthe.2005.06.036
36. Improved Lentiviral Vectors for Systemic Gene Transfer in the Absence of an Immune Response
Brian D. Brown, Ehud Hauben, Angelo Lombardo, Lucia Sergi Sergi, Maria Grazia Roncarolo and Luigi Naldini
Mol Ther 11: S15-S15; doi:10.1016/j.ymthe.2005.06.042
37. A Novel Form of Enzyme Replacement Therapy for ADA-Deficiency: In Vivo Transduction by Neonatal Injection of Lentivirus Expressing ADA
Denise A. Carbonaro, Xiangyang Jin, Denise Petersen and Donald B. Kohn
Mol Ther 11: S15-S16; doi:10.1016/j.ymthe.2005.06.037
38. Inhibition of Apolipoprotein B-100 Expression by Lentivirus Mediated RNA Interference in Mice after Stem Cell Transduction and Transplantation
Mikko P. Turunen, Petri I. Makinen, Pia Leppanen, Juulia Enback, Suvi Koota, Tero Vatanen and Seppo Yla-Herttuala
Mol Ther 11: S16-S16; doi:10.1016/j.ymthe.2005.06.043
39. Effects of Long-Term Expression of Activated Murine FVII in Normal and Hemophilic Mice
Majed N. Aljamali, Paris Margaritis, Rodney M. Camire and Katherine A. High
Mol Ther 11: S16-S16; doi:10.1016/j.ymthe.2005.06.038
40. Enhanced Factor IX Delivery from Bioengineered Hybrid Human Skeletal Muscle Co-Expressing VEGF
Lieven Thorrez, Herman Vandenburgh, Desire Collen, Janet Shansky, Thierry VandenDriessche and Marinee Chuah
Mol Ther 11: S17-S17; doi:10.1016/j.ymthe.2005.06.039
41. High Efficiency, Catheter-Based, Gene Transfer to the Large Animal Heart
David M. Kaye, Kenneth Chien, Masahiko Hoshijima, Krisztina Zsebo and John Power
Mol Ther 11: S17-S17; doi:10.1016/j.ymthe.2005.06.069
42. Uniform Scale-Independent Gene Transfer to Striated Muscle after Transvenular Extravasation of Vector
Kapil Gopal, Leonard T. Su, Zhonglin Wang, Xiaoqing Yin, Anthony Nelson, Benjamin W. Kozyak, James M. Burkman, Marilyn A. Mitchell, David W. Low, Charles R. Bridges and Hansell H. Stedman
Mol Ther 11: S17-S18; doi:10.1016/j.ymthe.2005.06.070
43. Targeting the Biology of Heart Disease: Engineered Zinc Finger Protein Repressors of Phospholamban as a Potential Therapy for Congestive Heart Failure
H. Steve Zhang, Lei Zhang, Yan Huang, Dinggang Liu, Yuxin Liang, Reed Hickey, Dmitry Guschin, Simon Chandler, Mike Kunis, Linda Hinh, Danny Xia, Xiaohong Zhong, S. Kaye Spratt, J. Tyler Martin, Casey C. Case, Dale Ando, Edward J. Rebar, Philip D. Gregory and Frank Giordano
Mol Ther 11: S18-S18; doi:10.1016/j.ymthe.2005.06.071
44. Development of AAV-Mediated Gene Therapy for Murine Models of Genetic Diseases Affecting the Heart
Christina A. Pacak, Cathryn Mah, Gabriel Gaidosh, Melissa Lewis, Raquel Torres, Kevin Campbell, Glenn A. Walter and Barry J. Byrne
Mol Ther 11: S18-S19; doi:10.1016/j.ymthe.2005.06.072
45. Adenoviral Gene Transfer of SERCA2a Restores Mechanical and Energetic Left-Ventricular Function in Spontaneously Diabetic Rats
Susumu Sakata, Yuri Sakata, Elie R. Chemaly, Prabhu M. Padmanabhan, Djamel Lebeche, Miyako Takaki, Federica delMonte and Roger J. Hajjar
Mol Ther 11: S19-S19; doi:10.1016/j.ymthe.2005.06.073
46. In Vivo Adenoviral Gene Transfer of Activated PI3-Kinase Rescues Cardiac Dysfunction and Injury Induced by Ischemia-Reperfusion after Chronic Cardiac Akt Activation
Tomohisa Nagoshi, Takashi Matsui, Takuma Aoyama, Ling Li, David A. Kass, Hunter C. Champion and Rosenzweig Anthony
Mol Ther 11: S19-S20; doi:10.1016/j.ymthe.2005.06.074
47. Ex Vivo Hypothermic Recirculatory Adenoviral Gene Transfer to the Transplanted Pig Heart
Keiji Oi, William R. Davies, Henry D. Tazelaar, Kent R. Bailey, Mark J. Federspiel, Stephen J. Russell and Christopher G.A. McGregor
Mol Ther 11: S20-S20; doi:10.1016/j.ymthe.2005.06.075
48. The Long-Term Effects of SERCA2a Overexpression in Large Animal Model of Heart Failure
Yoshiaki Kawase, Ryuichi Yoneyama, Kozo Hoshino, Jennifer McGregor, Thanh-Thao Ton-Nu, Tom G. Neilan, Robert A. Levine, Judy Hung, Motoya Hayase, Federica del Monte and Roger Hajjar
Mol Ther 11: S20-S20; doi:10.1016/j.ymthe.2005.06.076
49. Evaluation of Catheter-Based Deliveries of 10um Gelatin Hydrogel Microsphere, a Novel Non-Viral Vehicle, in a Porcine Heart
Kozo Hoshino, Ryuichi Yoneyama, Yoshiaki Kawase, Alec M. DeGrand, John V. Frangioni, Yasuhiko Tabata, Takeshi Kimura, Toru Kita, Roger J. Hajjar and Motoya Hayase
Mol Ther 11: S21-S21; doi:10.1016/j.ymthe.2005.06.077
50. Transcript Profiling Identifies Novel Role for SGK1 in Promoting Cardiomyocyte Survival
Takuma Aoyama, Takashi Matsui, Mikhail Novikov and Anthony Rosenzweig
Mol Ther 11: S21-S21; doi:10.1016/j.ymthe.2005.06.078
51. Adenoviral BDNF/Noggin-Induced Neurogenesis from Endogenous Neural Stem Cells Delays Motor Impairment and Extends Survival in a Transgenic Model of Huntington's Disease
Sung-Rae Cho, Eva Chmielnicki, Aris Economides and Steven A. Goldman
Mol Ther 11: S22-S22; doi:10.1016/j.ymthe.2005.06.079
52. AAV-Delivered RNAi Improves Cellular and Motor Phenotypes in a Mouse Model for Huntington's Disease
Scott Q. Harper, Patrick D. Staber, Xiaohua He, Ines H. Martins, Qinwen Mao, Henry L. Paulson, Robert M. Kotin and Beverly L. Davidson
Mol Ther 11: S22-S22; doi:10.1016/j.ymthe.2005.06.080
53. Post-Transcriptional Suppression of Striatal Mutant Huntingtin Leads to Mild Phenotypic Improvements in the R6/1 Mouse
Edgardo Rodriguez, Eileen Denovan-Wright, Kevin Nash, Alfred S. Lewin and Ronald J. Mandel
Mol Ther 11: S22-S23; doi:10.1016/j.ymthe.2005.06.081
54. Lentiviral-Mediated Silencing of SOD1 through RNA Interference Delays Disease Onset and Progression in a Mouse Model of ALS
Cedric Raoul and Patrick Aebischer
Mol Ther 11: S23-S23; doi:10.1016/j.ymthe.2005.06.082
55. Lentiviral-Mediated Silencing of Mutant SOD-1 Using RNAi Causes Long Term Correction of ALS in a Transgenic Mouse Model
Gareth S. Ralph, Pippa A. Radcliffe, Denise M. Day, Janine M. Carthy, Susan M. Kingsman, Kyriacos A. Mitrophanous, Mimoun Azzouz and Nicholas D. Mazarakis
Mol Ther 11: S23-S23; doi:10.1016/j.ymthe.2005.06.083
56. Amelioration of Neurodegenerative and Neuropathological Alterations in a Transgenic Model of Alzheimer's Disease: Targeting BACE1 with Small Interfering RNAs
Oded Singer, Robert A. Marr, Edward Rockenstein, Leslie Crews, Fred H. Gage, Inder M. Verma and Eliezer Masliah
Mol Ther 11: S23-S24; doi:10.1016/j.ymthe.2005.06.084
57. Therapy for Alzheimer's Disease by Neprilysin Gene Transfer
Robert A. Marr, Edward Rockenstien, Atish Mukherjee, Mark S. Kindy, Louis B. Hersh, Fred H. Gage, Eliezer Masliah and Inder M. Verma
Mol Ther 11: S24-S24; doi:10.1016/j.ymthe.2005.06.085
58. Rett Syndrome Is Reversible and Treatable by MeCP2 Gene Therapy into the Striatum in Mice
Ken-ichiro Kosai, Akira Kusaga, Takeo Isagai, Koji Hirata, Satoshi Nagano, Yoshiteru Murofushi, Tomoyuki Takahashi, Sachio Takashima and Toyojiro Matsuishi
Mol Ther 11: S24-S24; doi:10.1016/j.ymthe.2005.06.086
59. rAAV-Mediated Nigral Parkin Over-Expression Is Neuroprotective in the 6-OHDA Rat Model of Parkinson's Disease
Fredric P. Manfredsson, Alfred S. Lewin, Nicholas Muzyczka, Corinna Burger and Ronald J. Mandel
Mol Ther 11: S24-S25; doi:10.1016/j.ymthe.2005.06.087
60. Recovery of Vestibular Function Induced by math1 Gene Delivery
Hinrich Staecker, Mark Praetorius and Douglas E. Brough
Mol Ther 11: S25-S25; doi:10.1016/j.ymthe.2005.06.088
61. Higher In Vivo Maintenance, Biodistribution and Immunopotency of Dendritic Cell Vaccines Self-Differentiated through Lentiviral Vector Programming
Richard C. Koya, Takahiro Kimura, Antoni Ribas, Nori Kasahara and Renata Stripecke
Mol Ther 11: S25-S25; doi:10.1016/j.ymthe.2005.06.089
62. Transduction of CD34+ Hematopoietic Progenitor Cells with a SIV-Based Lentiviral Vector Expressing Antisense SIV Env Protects CD4+ T Cell Progeny from SIVmac239 Infection
S.E. Braun, F. Eng, M. Connole, C. Chen, B. Dropulic, G.K. Binder, X. Lu and R.P. Johnson
Mol Ther 11: S25-S26; doi:10.1016/j.ymthe.2005.06.090
63. A Nonhuman Primate Model for Testing Immuno Gene Therapies for AIDS Using Gene-Protected T Cells
Joern E. Schmitz, Felix Hermann, Sebastian Newrzela, Melisa Ricketts, Patricia Schult-Dietrich, Alexander Szyroki, Robert P. Johnson and Dorothee vonLaer
Mol Ther 11: S26-S26; doi:10.1016/j.ymthe.2005.06.091
64. Characterization of the Mechanism of Action of the Anti-HIV-1 Transgene F12-Vif
Rossella Lupo, Giuliana Vallanti, Maurizio Federico, Fulvio Mavilio and Chiara Bovolenta
Mol Ther 11: S26-S26; doi:10.1016/j.ymthe.2005.06.092
65. Protective Immunity Against Anthrax Lethal Toxin in Mice Immunized with an Ad-Based Vaccine Vector Expressing Lethal Factor
Julie L. Boyer, Tiffany B. Niven, Neil R. Hackett and Ronald G. Crystal
Mol Ther 11: S26-S27; doi:10.1016/j.ymthe.2005.06.093
66. A Protective Vaccine for the Rapid Response to Pandemic AVian Influenza
Wentao Gao, Adam Soloff, Xiuhua Liu, Angela Montecalvo, Yumiko Matsuoka, Paul D. Robbins, Roben O. Donis, Jacqueline M. Katz, Simon Barratt-Boyes and Andrea Gambotto
Mol Ther 11: S27-S27; doi:10.1016/j.ymthe.2005.06.044
67. Protective Immunity Against Yersinia pestis in Mice Immunized with an Ad-Based Vaccine Vector Expressing the Y. pestis F1 and V Antigens
Maria Chiuchiolo, Julie L. Boyer, Tiffany Niven, Anja Krause, Neil R. Hackett and Ronald G. Crystal
Mol Ther 11: S27-S27; doi:10.1016/j.ymthe.2005.06.045
68. Development of a Novel Non-Viral DNA Vaccine-Delivering Gene into the Nucleus of Dendritic Cells
Takashi Nakamra, Kentaro Kogure, Rumiko Moriguchi, Shiroh Futaki, Masahiro Fujimuro, Hideyoshi Yokosawa, Tsukasa Seya and Hideyoshi Harashima
Mol Ther 11: S27-S28; doi:10.1016/j.ymthe.2005.06.046
69. Tumor-Targeting Innumogene Therapy by Mesenchymal Stem Cells Expressing CX3CL1
Hong Xin, Masahiko Kanehira, Hiroyuki Mizuguchi, Takao Hayakawa, Toshihiro Nukiwa and Yasuo Saijo
Mol Ther 11: S28-S28; doi:10.1016/j.ymthe.2005.06.047
70. Systemic Administration of siRNA Against EWS-FLI1 Using a Targeted, Non-Viral Formulation Inhibits Growth in a Disseminated Murine Model of Ewing's Sarcoma
Jeremy D. Heidel, Siwen Hu-Lieskovan, Derek W. Bartlett, Timothy J. Triche and Mark E. Davis
Mol Ther 11: S28-S29; doi:10.1016/j.ymthe.2005.06.048
71. Intratumoral Delivery of Small Interfering RNA for Inhibition of Tumor Progression in Mice
Yuki Takahashi, Makiya Nishikawa and Yoshinobu Takakura
Mol Ther 11: S29-S29; doi:10.1016/j.ymthe.2005.06.049
72. Capsid Modifications Overcome Low Heterogeneous Expression of Heparan Sulfate Proteoglycan That Limits AAV2-Mediated Gene Transfer and Therapeutic Efficacy in Human Ovarian Carcinoma
Jeffrey S. Bartlett and Wenfang Shi
Mol Ther 11: S29-S29; doi:10.1016/j.ymthe.2005.06.050
73. Fully Retargeted Oncolytic Measles Viruses for Cancer Therapy
Takafumi Nakamura, Mary Harvey, Suzanne Greiner, Kah-Whye Peng and Stephen J. Russell
Mol Ther 11: S30-S30; doi:10.1016/j.ymthe.2005.06.051
74. Specific Delivery of hTRAIL and Inhibition of Ewing's Sarcoma Growth by Transplantation of Viral Vector-Transduced Bone Marrow-Derived Mesenchymal Stem Cells (MSC)
Jeffrey S. Bartlett, Wenfang Shi and Carmel Lawrencia
Mol Ther 11: S30-S30; doi:10.1016/j.ymthe.2005.06.052
75. Molecular Imaging of an EGFP-DRD2-Expressing Vaccinia Virus
Navneet Mehta, Nan Tang, Hui Deng, Deborah Scollard, James Jonkman, Brian C. Wilson, Raymond M. Reilly and Judith A. McCart
Mol Ther 11: S31-S31; doi:10.1016/j.ymthe.2005.06.053
76. New Strategy To Improve Imaging and Retargeting of HSV-1 Vectors
Paola Grandi, Trevor D. McKee, Wilson Mok, Juliet L. Fernandez, Xandra O. Breakefield and Rakesh K. Jain
Mol Ther 11: S31-S31; doi:10.1016/j.ymthe.2005.06.054
77. Efficient Transduction and Therapy of Malignant Glioma by Lentiviral Vectors Pseudotyped with LCMV Glycoproteins
Hrvoje Miletic, Yvonne Fischer, Harald Neumann, Tsanan Giroglou, Manuel M. Hermann, Werner Stenzel, Maria A. Rueger, Yannic Waerzeggers, Uwe Himmelreich, Mathias Hoehn, Andreas H. Jacobs, Martina Deckert and Dorothee von Laer
Mol Ther 11: S31-S32; doi:10.1016/j.ymthe.2005.06.055
78. Expression of the Herpes Simplex Virus Thymidine Kinase Gene by a Promoter Region of the Human SPARC Gene Inhibits Human Melanoma Cell Growth In Vitro and In Vivo
Maria V. Lopez, Patricia V. Blanco, Diego L. Viale, Eduardo A. Cafferata, David Gould, Yuti Chernajovsky and Osvaldo Podhajcer
Mol Ther 11: S32-S32; doi:10.1016/j.ymthe.2005.06.056
79. Real Time Fluorescent Tracking of Dynamic Variegation by Retrovirus Vectors in Stem Cells
James Ellis, John Ramunas, Liam Kelly, Tanya Sukonnik and Eric Jervis
Mol Ther 11: S33-S33; doi:10.1016/j.ymthe.2005.06.057
80. Insulation of Oncoretrovirus Vectors with the cHS4 Chromatin Insulator Is Associated with an Open Chromatin Histone Code
Changlong Li and David W. Emery
Mol Ther 11: S33-S33; doi:10.1016/j.ymthe.2005.06.058
81. A Retrovirus Vector Screen for the Identification of Novel Chromatin Insulators and Enhancers
Amy C. Groth, George Stamatoyannopoulos and David W. Emery
Mol Ther 11: S33-S34; doi:10.1016/j.ymthe.2005.06.059
82. Targeted Pancreatic Cancer-Specific Gene Therapy Controlled by a Molecular-Engineered Human Cholecystokinin Type-A Receptor (CCKAR) Promoter in In Vivo Imaging Models
Xiaoming Xie, Zheng Li, Qingqing Ding, Hus-Ping Kuo, James L. Abbruzzese and Mien-Chie Hung
Mol Ther 11: S34-S34; doi:10.1016/j.ymthe.2005.06.060
83. Persistent and Position Independent Transgene Expression in Erythroid Cells Transduced by Lentiviral Vectors
Annarita Miccio, Francesco Lotti, Claudia Rossi and Giuliana Ferrari
Mol Ther 11: S34-S34; doi:10.1016/j.ymthe.2005.06.061
84. Assessing Hemostatic Efficacy of Continuous Expression of Factor VIIa after AAV-Mediated, Liver-Directed Gene Transfer in Hemophilia A and B Mice
Alexander Schlachterman, Paris Margaritis, Majed Aljamali, Jianhua Liu, Valder Arruda and Katherine High
Mol Ther 11: S35-S35; doi:10.1016/j.ymthe.2005.06.062
85. Development of Zinc Finger Nucleases for Therapeutic Gene Correction of Sickle Cell Anemia
Jeffrey C. Miller, Fyodor D. Urnov, Ya-li Lee, Jeremy Rock, Tyler Sorba, Sarah Patterson, Philip D. Gregory, Michael C. Holmes and Edward J. Rebar
Mol Ther 11: S35-S35; doi:10.1016/j.ymthe.2005.06.063
86. Transcriptional Gene Silencing in Human Cells
Zhaoxia Chen, Ali Ehsani, Riggs Art, Rossi J. John and Kevin V. Morris
Mol Ther 11: S35-S36; doi:10.1016/j.ymthe.2005.06.064
87. Determinants of Toxicity Induced by In Vivo Expression of Short Hairpin RNA from AAV Vectors
Dirk Grimm, Konrad L. Streetz, Kusum Pandey, Theresa A. Storm and Mark A. Kay
Mol Ther 11: S36-S36; doi:10.1016/j.ymthe.2005.06.065
88. Driving shRNA Transcription from PolII Promoters in Mammalian Cells
Jeffery C. Giering and Mark A. Kay
Mol Ther 11: S36-S36; doi:10.1016/j.ymthe.2005.06.066
89. Amelioration of Gamma Retroviral Silencing during Embryonic Stem Cell-Derived Hematopoiesis: Preclinical Assessment of Safety-Improved Vectors
Ali Ramezani, Teresa S. Hawley and Robert G. Hawley
Mol Ther 11: S36-S37; doi:10.1016/j.ymthe.2005.06.067
90. In Vitro and In Vivo Gene Expression of Lentiviral Vectors in CD4+ T Cells
Kit L. Shaw, Karen Pepper, Denise Petersen, Vesa Kaartinen and Donald B. Kohn
Mol Ther 11: S37-S37; doi:10.1016/j.ymthe.2005.06.068
91. Insertion of the cHS4-Insulator into Lentiviral Vectors: Use of Real-Time PCR in Order To Analyze the Effects on Transgene Expression and Viral Titre
Johan Jakobsson, Troels Tolstrup Nielsen, Nina Rosenqvist and Cecilia Lundberg
Mol Ther 11: S37-S38; doi:10.1016/j.ymthe.2005.06.097
92. Efficient Trangene Expression in Central Nervous System through a Non-Integrative Lentiviral Vector
Stephanie Philippe, Che Serguera, Sebastien Bonnel, Christelle Vetu, Martine Barkats, Caroline Petit, Marc Abitbol, Chamsy Sarkis and Jacques Mallet
Mol Ther 11: S38-S38; doi:10.1016/j.ymthe.2005.06.098
93. Diminished Mobilization of Self-Inactivating (SIN) Lentiviral Vectors Containing Globin Regulatory Elements Compared to Those Containing a Retroviral Long Terminal Repeat
Hideki Hanawa, Derek A. Persons, Takashi Shimada and Arthur W. Nienhuis
Mol Ther 11: S38-S38; doi:10.1016/j.ymthe.2005.06.099
94. Transgene Expression with Integration-Deficient HIV-1 Based Lentiviral Vectors Expressing Class I Integrase Mutants
G. Joseph, J. Marsh, T. Johnson and K. Cornetta
Mol Ther 11: S38-S39; doi:10.1016/j.ymthe.2005.06.100
95. Transduction and Expression of shRNAs Via Lentiviral Bectors Bearing a U6 RNA Polymerase III Promoter, but Not an H1 Promoter, Induce Elevated Apoptosis in Human Primary Peripheral Blood T Lymphocytes
Dong Sung An, Xiao-Feng Qin, Si-Hua Mao, Vincent C. Auyeung, David Baltimore and Irvin S.Y. Chen
Mol Ther 11: S39-S39; doi:10.1016/j.ymthe.2005.06.101
96. Ocular Gene Transfer Using EIAV Vectors and an RPE-Specific Promoter
Shu Kachi, Katie Binley, Naoyasu Umeda, Hideo Akiyama, Raquel Lima e Silva, Wei-Hong Xiao, Michiko Kachi, Margaret Esapa, Sharifah Iqball, Stuart Naylor and Peter A. Campochiaro
Mol Ther 11: S39-S39; doi:10.1016/j.ymthe.2005.06.102
97. Type I Interferon Response Against Virus Vectors and Non-Viral Gene Transfer
Riikka Pellinen, Outi Meril|[auml]|inen, Saara Lehmusvaara, Tuula Salonen, Katja H|[auml]|kkinen, Tanja Hakkarainen, Elisa V|[auml]|h|[auml]|kangas, Kari Airenne, Ilkka Julkunen, Ari Hinkkanen and Jarmo Wahlfors
Mol Ther 11: S40-S40; doi:10.1016/j.ymthe.2005.06.103
98. Stable Lentivirus-Mediated RNA Interferen Comparison of U6 and H1 Promoters in Endothelial Cells and GFP Knockdown in Mouse Brain
Petri I. Makinen, Jonna K. Koponen, Anna-Mari Turunen, Tarja M. Malm, Jari Koistinaho, Mikko P. Turunen and Seppo Yla-Herttuala
Mol Ther 11: S40-S40; doi:10.1016/j.ymthe.2005.06.104
99. Use of a Liver-Specific Lentivirus Vector for Characterization of Hepatocyte-Like Cells from Human Differentiated Embryonic Stem Cells (hESC)
Yuyou Duan Ph.D, Naoki Yamamoto Ph.D/M.D., Jian Wu Ph.D/M.D., Sanjeev Gupta M.D. and Mark A. Zern M.D.
Mol Ther 11: S40-S41; doi:10.1016/j.ymthe.2005.06.105
100. Development of an Integrase Deficient FIV Vector for Transient Gene Expression
Marisa Banasik, Melissa Hickey and Paul McCray Jr. MD
Mol Ther 11: S41-S41; doi:10.1016/j.ymthe.2005.06.106
101. Development of Lentiviral Vectors with Respiratory Epithelial Specific Transgene Expression
Dinithi Senadheera MS, Benjamin Hendrickson MS, Denise Petersen, Karen Pepper and Carolyn Lutzko PhD
Mol Ther 11: S41-S41; doi:10.1016/j.ymthe.2005.06.107
102. Overexpression of the Myostatin Antagonist Follistatin in Normal Myoblasts Genetically Modified with a Lentivirus
Basma F. Benabdallah, Joel Rousseau, Manaf Bouchentouf and Jacques P. Tremblay
Mol Ther 11: S42-S42; doi:10.1016/j.ymthe.2005.06.108
103. PGK and CMV Promoters Exert the Strongest Activity in Lentiviral Gene Transduction of Myeloid Cells Including Mature Neutrophils
Yasushi Soda, Kenzaburo Tani, Xiaojin Li, Yuansong Bai, Seok-Goo Cho, Muneyoshi Futami, Minghan Chen, Seiichiro Kobayashi, Hiroyuki Miyoshi, Hideki Sumimoto, Shoichi Ohga, Toshiro Hara, Arinobu Tojo and Shigetaka Asano
Mol Ther 11: S42-S42; doi:10.1016/j.ymthe.2005.06.109
104. Stable High Level Gene Expression by Minimum Sized Murine Leukemia Virus (MLV)-Based Retroviral Vectors in the Mouse Model
Seung Shin Yu, Youngtae Hong, Sujeong Kim, Chang Wan Joo, Nam Kyung Yoon and Sunyoung Kim
Mol Ther 11: S42-S43; doi:10.1016/j.ymthe.2005.06.110
105. Comparative Study on the Gene Expression Profile of HIV-1 Based Lentiviral Vectors Transduced Human and Murine Cells
Yuan Zhao, Selina Azam and Robin Thorpe
Mol Ther 11: S43-S43; doi:10.1016/j.ymthe.2005.06.111
106. Measles Virus Host Defense Evasion Proteins V and C Have Also Transcription Modulation and Infectivity Factor Functions
Patricia Devaux, Warangkhana Songsungthong, Christoph Springfeld, Veronika von Messling and Roberto Cattaneo
Mol Ther 11: S43-S43; doi:10.1016/j.ymthe.2005.06.112
107. Sustained Stable Gene Expression Induced by a Cytoplasmic RNA-Virus Vector Based on Mutant Sendai Virus Strain cl.151
Ken Nishimura, Hiroaki Segawa, Takahiro Goto, Mariko Morishita, Takemasa Sakaguchi, Tetsuya Yoshida, Kozo Takayama and Mahito Nakanishi
Mol Ther 11: S44-S44; doi:10.1016/j.ymthe.2005.06.113
108. The Complete Nucleotide Sequence of Sendai Virus Isolate BB1 and Comparison with Other Isolates
Yu Yang, Lufeng Ren, Xiaoyan Dong and Xiaobing Wu
Mol Ther 11: S44-S44; doi:10.1016/j.ymthe.2005.06.469
109. Expression of Porcine |[alpha]|(1|[ndash]|3)galactosyltransferase in Non-Human Primate Hematopoietic Progenitors Following Retroviral Mediated Gene Transfer
Lorenzo Benatuil and John Iacomini
Mol Ther 11: S44-S45; doi:10.1016/j.ymthe.2005.06.114
110. Performance of Different AAV Serotype Vectors Following Injection into the Deep Cerebellar Nuclei of ASMKO Mouse Brain
James C. Dodge, Jennifer Clarke, Anthony Song, Jie Bu, Qi Zhao, Tatyana V. Taksir, Denise Griffiths, Lamya S. Shihabuddin, Catherine R. O'Riordan, Marco A. Passini, Ed H. Schuchman and Gregory R. Stewart
Mol Ther 11: S45-S45; doi:10.1016/j.ymthe.2005.06.115
111. AAV7, 8, and 9 Are More Efficient and Less Immunogenic Vectors for Muscle-Directed Gene Therapy for Hemophilia B
Lili Wang, Jean-Pierre Louboutin, Yan Li and James M. Wilson
Mol Ther 11: S45-S45; doi:10.1016/j.ymthe.2005.06.116
112. Strong Transgene-Specific Immune Responses Can Be Elicited with Novel Adeno-Associated Virus Vectors in Mice
Yan Zhi, Julie Johnston, Di Wu, Joanita Figueredo, Martin Lock, Peter Bell, Guangping Gao and James M. Wilson
Mol Ther 11: S45-S46; doi:10.1016/j.ymthe.2005.06.117
113. Manipulating AAV2 Tropism for Enhanced Delivery of AAV Vectors to the Spinal Cord
Adam Davis, Matthew Stachler, Wenfang Shi, James Liu, Nicholas Boulis and Jeffrey Bartlett
Mol Ther 11: S46-S46; doi:10.1016/j.ymthe.2005.06.118
114. Efficient Arterial Formation at the Sites of Adult Neo-Angiogenesis Requires the Recruitment of Bone Marrow Cells through the Neuropilin-1 (NP-1) Receptor
Serena Zacchigna, Nikola Arsic, Lucia Pattarini, Silvia Moimas, Alessandro Carrer, Lorena Zentilin, Alessandro Salvi, Gianfranco Sinagra and Mauro Giacca
Mol Ther 11: S46-S46; doi:10.1016/j.ymthe.2005.06.119
115. In Vivo Expression of Human Cob(I)alamin Adenosyltransferase Using rAAV Serotypes 1,2 and 8, an Approach to Gene Therapy for Methylmalonic Aciduria (MMA)
Kirsten E. Erger, Thomas J. Conlon, Travis L. Cossette, Thomas A. Bobik and Terence R. Flotte
Mol Ther 11: S47-S47; doi:10.1016/j.ymthe.2005.06.120
116. Functional Comparison of Four CFTR rAAV Vectors with Alternative Transcriptional Elements in Cell Lines and Polarized Human CF Airway Epithelia
Liang Zhang, Benjamin Dutzar, Keith Munson, Barrie Carter and John F. Engelhardt
Mol Ther 11: S47-S47; doi:10.1016/j.ymthe.2005.06.121
117. AAV-Mediated Erythropoietin Gene Transfer Protects from Genetic and Light-Induced Retinal Degeneration
Mariacarmela Allocca, Tonia S. Rex, Luciano Domenici, Jean Bennet, Victor M. Rivera and Alberto Auricchio
Mol Ther 11: S48-S48; doi:10.1016/j.ymthe.2005.06.122
118. Self-Complementary AAV Vectors Pseudotyped with Either Serotype 5 or 8 Capsids Give Therapeutic Human Factor IX Levels at Significantly Reduced Doses in Non-Human Primates
John T. Gray, Andrew M. Davidoff and Amit C. Nathwani
Mol Ther 11: S48-S48; doi:10.1016/j.ymthe.2005.06.123
119. Intraperitoneal Transduction of Adeno-Associated Virus 2 Expressing Angiostatin and Endostatin Synergistically Augments Paclitaxel Therapy and Tumor-Free Survival in a Mouse Model of Epithelial Ovarian Cancer
Tatyana Isayeva, Changchun Ren and Selvarangan Ponnazhagan
Mol Ther 11: S48-S49; doi:10.1016/j.ymthe.2005.06.124
120. Stimulation of the Synthesis of Type-II Collagen and Extracellular Matrix in Human Normal and Osteoarthritic Articular Cartilage Explants In Situ by Overexpression of Human sox9 by rAAV-Mediated Gene Transfer
Henning Madry, Tanja Thurn, Dieter Kohn, Ernest F. Terwilliger and Magali Cucchiarini
Mol Ther 11: S49-S49; doi:10.1016/j.ymthe.2005.06.125
121. VEGF-Induced Angiogenesis Does Not Have a Favorable Effect on Muscle Perfusion: A Relevant Role of Long-Term Angiopoietin-1 Expression in the Formation of Functional Blood Vessels
Serena Zacchigna, Ennio Tasciotti, Nikola Arsic, Oreste Sorace, Marini Cecilia, Silvia Pardini, Debora Petroni, Claudia Kusmic, Lucia Pattarini, Silvia Moimas, GianMario Sambuceti and Mauro Giacca
Mol Ther 11: S49-S49; doi:10.1016/j.ymthe.2005.06.126
122. Enhanced Expression of Glutamate Decarboxylase 65 Significantly Improves Rat Parkinsonian Symptom
Boyoung Lee, Young Ran Nam, Sung Jin Kim, Jin Hwan Oh, Yoon Hee Choi, Jin Woo Chang and Heuiran Lee
Mol Ther 11: S50-S50; doi:10.1016/j.ymthe.2005.06.127
123. rAAV-pdx-1 Augmented the Insulin-Producing Cells
Hua Li, Karen S. Lam, Sidney Tam, Weidong Xiao, Paul Tam and Ruian Xu
Mol Ther 11: S50-S50; doi:10.1016/j.ymthe.2005.06.128
124. The |[ldquo]|Perivascular Pump|[rdquo]| Driven by Arterial Pulsation Is a Powerful Mechanism for the Distribution of Therapeutic Molecules within the Brain
Piotr Hadaczek, Hanna Mirek, Laszlo Tamas, Martha C. Bohn, Charles Noble, John W. Park and Krystof Bankiewicz
Mol Ther 11: S50-S51; doi:10.1016/j.ymthe.2005.06.129
125. AAV Vector-Mediated Neonatal Gene Transfer: Efficient Transgene Expression in Muscles after Intraperitoneal Cavity Vector Injection
Tsuyoshi Ogura, Hiroaki Mizukami, Jun Mimuro, Takashi Okada, Hiromi Hamada, Akihiro Kume, Hiroyuki Yoshikawa, Yoichi Sakata and Keiya Ozawa
Mol Ther 11: S51-S51; doi:10.1016/j.ymthe.2005.06.130
126. The Formation of Stable and Mature Blood Vessels Requires the Proper Timing of VEGF Expression
Sabrina Tafuro, Serena Zacchigna, Lorena Zentilin, Marina Dapas and Mauro Giacca
Mol Ther 11: S51-S51; doi:10.1016/j.ymthe.2005.06.131
127. Intraarticular Gene Transfer of Rat TNFR:Fc Suppressed CIA Arthritis
Ai Zhi Zhao, Kai Gao, Xiao Yan Dong, Jian Qiang Peng and Xiao Bing Wu
Mol Ther 11: S51-S52; doi:10.1016/j.ymthe.2005.06.132
128. Transduction of Hepatic Oval Cells, Stem Cells, In Vitro by Adeno-Associated Virus Vectors
Hong You, Ping Wang, Jidong Jia, Liu Yong and Paul L. Hermonat
Mol Ther 11: S52-S52; doi:10.1016/j.ymthe.2005.06.133
129. Development of Vectors Utilizing Strong Neuronal Cell Type Specific Promoters for High Level Expression of Beta Glucuronidase in the Central Nervous System
Tupur Husain and John H. Wolfe
Mol Ther 11: S52-S52; doi:10.1016/j.ymthe.2005.06.134
130. Characterization of a Murine Adeno-Associated Virus (AAV-mo.1) Capsid
Michael Lochrie, Gwen Tatsuno, Alejandra Arbetman, Peter Smith, Jennifer Wellman, Shang-zhen Zhou, Glenn Pierce and Peter Colosi
Mol Ther 11: S52-S53; doi:10.1016/j.ymthe.2005.06.135
131. Recombinant Adeno-Associated Virus 2-Mediated Transfer of the Human Superoxide-Dismutase Gene Does Not Confer Radioresistance on HeLa Cervical Carcinoma Cells
Marlon R. Veldwijk, Carsten Herskind, Stephanie Laufs, W. Jens Zeller, Stefan Fruehauf and Frederik Wenz
Mol Ther 11: S53-S53; doi:10.1016/j.ymthe.2005.06.136
132. An Optimized CsCl Gradient -Based Method to Generate High Concentration AAV Vector Stocks of High Purity and In Vivo Potency
Mario Cooper, Bernd Hauck, Jeff Watkins, Megan Erne, Federico Mingozzi, Roland Herzog and Fraser Wright
Mol Ther 11: S53-S54; doi:10.1016/j.ymthe.2005.06.137
133. Comparison of Adeno-Associated Viral Vector Serotypes 1, 2, 5 and 6 for Gene Transfer to Neurons and Glia In Vitro
Doug B. Howard, Juan Li, Yun Wang and Brandon K. Harvey
Mol Ther 11: S54-S54; doi:10.1016/j.ymthe.2005.06.138
134. Toxicology and Biodistribution Studies of a Recombinant Adeno-Associated Virus 1 (rAAV1) Alpha-1 Antitrypsin (AAT) Vector
Amy E. Poirier, Thomas J. Conlon, Lynn A. Combee, Kirsten E. Erger and Terence R. Flotte
Mol Ther 11: S54-S54; doi:10.1016/j.ymthe.2005.06.139
135. AAV-Mediated Gene Delivery To Evaluate the Biology of an Inherited Macular Degeneration
Nicholas W. Keiser, Daniel C. Chung, Waixing Tang, Zhanyong Wei, Albert Maguire, Jean Bennett and Jeannette L. Bennicelli
Mol Ther 11: S54-S55; doi:10.1016/j.ymthe.2005.06.140
136. Recombinant Adeno-Associated Virus 2-Mediated Ectopic Expression of |[alpha]|4|[beta]|1 Integrin in Mouse Mesenchymal Stem Cells Enhances Repopulation to Bone upon Syngeneic Transplantation in an Immunocompetent Mouse Model
Sanjay Kumar and Selvarangan Ponnazhagan
Mol Ther 11: S55-S55; doi:10.1016/j.ymthe.2005.06.141
137. Localization of Regions in CD46 That Interact with Adenovirus
Anuj Gaggar, Dmitry M. Shayakhmetov, M. Kathryn Liszewski, John P. Atkinson and Andre Lieber
Mol Ther 11: S55-S55; doi:10.1016/j.ymthe.2005.06.142
138. Blood Factors Affect Adenovirus Infectivity and Bio-Distribution In Vivo
Dmitry M. Shayakhmetov
Mol Ther 11: S55-S56; doi:10.1016/j.ymthe.2005.06.143
139. Priming and Boosting Efficiency of Chimp and Human Adenoviral Vectors in the Setting of Pre-Existing Immunity in Non-Human Primates
Joanita Figueredo, Roberto Calcedo, Jim Miller, Gary Kobinger, Rebecca Grant, Guangping Gao and James M. Wilson
Mol Ther 11: S56-S56; doi:10.1016/j.ymthe.2005.06.144
140. Primary Adenovirus Specific Cytotoxic T Lymphocyte Response Occurs after Viral Clearance and Liver Enzyme Elevation
Jian Chen, Allan J. Zajac, Sylvia A. McPherson, Xin Xu, PingAr Yang, Qi Wu, David T. Curiel and John D. Mountz
Mol Ther 11: S56-S57; doi:10.1016/j.ymthe.2005.06.145
141. Adenovirus Vaccine to Ebola Virus: Mechanism of Protection and Impact of Pre-Existing Immunity to the Vaccine Carrier
Gary P. Kobinger, Heinz Feldmann, Yan Zhi, Gregory Schumer, Guangping Gao, Frederik Feldmann, Steven Jones and James M. Wilson
Mol Ther 11: S57-S57; doi:10.1016/j.ymthe.2005.06.146
142. Molecular and Macromolecular Alterations of Recombinant Adenoviral Vectors Do Not Eliminate Changes in Hepatic Drug Metabolism
Shellie M. Callahan, Michael P. Boquet, Piyanuch Wonganan and Maria A. Croyle
Mol Ther 11: S57-S57; doi:10.1016/j.ymthe.2005.06.147
143. Regulated, High Capacity Adenoviral Vectors Mediated Long-Term Gene Expression in the Brain Even in the Presence of a Peripheral Immune Response to Adenovirus
Weidong Xiong, Shyam Goverdhana, James F. Curtin, Carlos Barcia-Gonzalez, Jeffrey M. Zirger, Gwendalyn D. King, Sandra A. Sciascia, Mariana Puntel, Marianela Candolfi, Donna Palmer, Philip Ng, Pedro R. Lowenstein and Maria G. Castro
Mol Ther 11: S58-S58; doi:10.1016/j.ymthe.2005.06.148
144. In Vivo Studies on the Toxicity of Adenovirus Vectors for Kupffer Cells
Elanchezhiyan Manickan, Jeffrey S. Smith, Jie Tian and Andrew P. Byrnes
Mol Ther 11: S58-S58; doi:10.1016/j.ymthe.2005.06.149
145. Evaluation of Biodistribution and Safety of Adenovirus Vectors Containing B-Group Fibers after Intravenous Injection into Baboons
Shaoheng Ni, Kathrin Bernt, Zong-Yi Li, Hans-Peter Kiem and Andre Lieber
Mol Ther 11: S58-S59; doi:10.1016/j.ymthe.2005.06.150
146. T Cell Response Against the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gene
Maria Limberis, Joanita Figueredo and James M. Wilson
Mol Ther 11: S59-S59; doi:10.1016/j.ymthe.2005.06.151
147. Adenovirus Vector E4 Gene Regulates Connexin 40 and 43 Expression in Endothelial Cells Via PKA and PI3K Signal Pathways
Joseph Cheng, Fan Zhang, George Lam, David Jin, Loic Vincent, Neil R. Hackett, Shiyang Wang, Lauren M. Young, Barbara Hempstead, Ronald G. Crystal and Shahin Rafii
Mol Ther 11: S59-S59; doi:10.1016/j.ymthe.2005.06.159
148. The Transgene Cassette Is Not Fully Responsible for Alterations of Renal Cytochrome P450 Expression after Systemic Administration of Recombinant Adenovirus
Hong T. Le, Michael P. Boquet, Erin A. Clark, Shellie M. Callahan and Maria A. Croyle
Mol Ther 11: S59-S60; doi:10.1016/j.ymthe.2005.06.152
149. Transient Kupffer Cell Saturation, Via Adenovirus or Adenoviral Protein, Enhances Expression of Reporter Virus
Viraj P. Mane, Christian Clarke, Lali Medina-Kauwe, Milton Finegold and Brendan Lee
Mol Ther 11: S60-S60; doi:10.1016/j.ymthe.2005.06.153
150. Pre-Existing Nab and Neutralization of Therapeutic Dose Adenovirus Serotypes In Vitro
Edward C. Nwanegbo, Wentao Gao, Andrea Gambotto and Paul Robbins
Mol Ther 11: S60-S60; doi:10.1016/j.ymthe.2005.06.154
151. Evaluation of a Serotype 35 Fiber Containing Adenovirus Vector for Vaccination
Nelson C. Di Paolo, Shaoheng Ni, Anuj Gaggar, Zong-Yi Li and Andre Lieber
Mol Ther 11: S61-S61; doi:10.1016/j.ymthe.2005.06.155
152. Coxsackievirus-Adenovirus Receptor (CAR) and |[alpha]|v|[beta]|3 or |[alpha]|v|[beta]|5 Integrin Independent Internalization of Porcine Adenoviral Vectors: Implications in Gene Therapy
Dinesh S. Bangari and Suresh K. Mittal
Mol Ther 11: S61-S61; doi:10.1016/j.ymthe.2005.06.156
153. Adenoviral Gene Therapy Vectors Expressing the Adenovirus Death Protein Demonstrate Increased Transgene Expression In Vivo as Demonstrated by Dose-Volume Histogram Analysis of Reporter Gene Activity
Kenneth N. Barton, Stephen L. Brown, Jae Ho Kim, Hans Stricker, Kastytis Karvelis, Mei Lu and Svend O. Freytag
Mol Ther 11: S61-S62; doi:10.1016/j.ymthe.2005.06.157
154. Relationship between the Expression of Membrane Receptors (CAR, Integrin |[alpha]|v|[beta]|3 and Integrin |[alpha]|v|[beta]|5 ) and Adenoviral Transduction Efficiency
Hiroyuki Inoue, Terumasa Hisano, Yukoh Nakazaki, Gaku Sakaguchi, Ryo Kurita, Koichi Takayama, Yoichi Nakanishi and Kenzaburo Tani
Mol Ther 11: S62-S62; doi:10.1016/j.ymthe.2005.06.158
155. Oral Delivery of Recombinant Vaccinia Viruses Expressing Adjuvanted Islet Autoantigens Protects NOD Mice from Autoimmune Diabetes
William H.R. Langridge, Bela Denes, Nadia Fodor, Valentina Krausova, Tatyana Timiryasova, David Henderson, John Hough, Jie Yu and Istvan Fodor
Mol Ther 11: S62-S62; doi:10.1016/j.ymthe.2005.06.470
156. Update on Genomic HSV Vector-Related Cytotoxicity: A Vector Preserving the Differentiation Potential of Embryonic and Adult Adipose Stem Cells
Julie Fradette, Steven K. Wendell, Jim Wechuck, David M. Krisky, Darren Wolfe, William F. Goins and Joseph C. Glorioso
Mol Ther 11: S62-S63; doi:10.1016/j.ymthe.2005.06.160
157. Quantitation of Long-Term Gene Expression from the HSV-1 Latency-Associated Promoter in the Mouse Brain Following Intracranial Injection
Bradford K. Berges, Ananya Gupta, John H. Wolfe and Nigel W. Fraser
Mol Ther 11: S63-S63; doi:10.1016/j.ymthe.2005.06.161
158. Gene Therapy for Chronic Pain Control: Perspectives of HSV-1 Mediated Gene Transfer to Supraspinal Centres
Isabel Martins, Marta Pinto, Steven Wilson, Deolinda Lima and Isaura Tavares
Mol Ther 11: S63-S64; doi:10.1016/j.ymthe.2005.06.162
159. Unexpected Genetic Alterations Occur in Untargeted Genes during the Construction of Viral Vectors
Megan J. Dambach, Jordan Trecki, Natalia Martin and Nancy S. Markovitz
Mol Ther 11: S64-S64; doi:10.1016/j.ymthe.2005.06.163
160. Systemic Oncolytic Herpes Simplex Virus Therapy of Spontaneously Arising Prostate Cancer in Transgenic TRAMP Mice
Susan Varghese, Samuel D. Rabkin, Petur G. Nielsen, Renbin Liu, Wenzheng Wang and Robert L. Martuza
Mol Ther 11: S64-S65; doi:10.1016/j.ymthe.2005.06.164
161. Targeting HSV Infection to gD Receptor-Negative Cells Using Soluble gD Receptors
Heechung Kwon, Qing Bai, Kelly Felmet, Hyun-Jung Baek, Gyuyoup Kim, William F. Goins, Justus F. Cohen and Joseph C. Glorioso
Mol Ther 11: S65-S65; doi:10.1016/j.ymthe.2005.06.165
162. Targeted HSV-1 Infection by Adapters for Glycoprotein D: Variable Infection Efficiency Dependent on Ligand Choice
Kenji Nakano, Williams F. Goins, Justus B. Cohen and Joseph C. Glorioso
Mol Ther 11: S65-S65; doi:10.1016/j.ymthe.2005.06.166
163. Engineered of a Highly Efficient Cell Cycle Regulatable-HSV-1 Amplicon Viral Vector
Grace Ying Wang, Ivy A.W. Ho, Kam M. Hui and Paula Y.P. Lam
Mol Ther 11: S65-S66; doi:10.1016/j.ymthe.2005.06.167
164. Bioluminescence Imaging in the CNS after HSV Amplicon Vector Delivery
Sam Wang, Lisa Pike, Jeremy Petravicz and Xandra O. Breakefield
Mol Ther 11: S66-S66; doi:10.1016/j.ymthe.2005.06.168
165. Tracking of Baculovirus Biodistribution In Vivo by Magnetic Resonance Imaging
Jani K. Raty, Thomas Wirth, Kari J. Airenne, Tuulia Huhtala, Timo Liimatainen, Ale Narvanen, Juhana Hakumaki and Seppo Yla-Herttuala
Mol Ther 11: S66-S66; doi:10.1016/j.ymthe.2005.06.169
166. Recombinant Baculovirus Vectors Containing Inverted Terminal Repeats from Adeno-Associated Virus Improve Gene Expression in Neurons and Astrocytes
Cao Yang Wang and Shu Wang
Mol Ther 11: S66-S66; doi:10.1016/j.ymthe.2005.06.471
167. Both Oncolysis and Tumor Immunity Are Involved in an Autitumoral Efficacy by Intratumoral Injection of Recombinant Vaccinia Virus (TK Deleted, hGM-CSF Inserted Wyeth Strain) in a VX2 Rabbit Model
Joon-Hyeong Kim, Byeong-Ho Park, Jong-Young Oh, David H. Kirn, Steve H. Thorne, Jae-Seok Kim and Tae-Ho Hwang
Mol Ther 11: S67-S67; doi:10.1016/j.ymthe.2005.06.170
168. Antitumoral Efficacy of Multiple Injection of JX-594 (Thymidine Kinase (TK) Deleted, Human GM-CSF Inserted Wyeth Strain) Via Tail Vein in N-Nitrosomorpholine (NNM) Treated Rats
Jae-seok Kim, June-Hyung Kim, Jong-yeong Oh, Byeong-ho Park, Jin-Han Yoon, Steve H. Thorne, David H. Kirn and Tae-ho Hwang
Mol Ther 11: S67-S67; doi:10.1016/j.ymthe.2005.06.171
169. The Creation of Novel Oncolytic Vaccinia Virus Vectors for Efficient Systemic Delivery of Transgenes to Tumors
Steve H. Thorne and David H. Kirn
Mol Ther 11: S67-S67; doi:10.1016/j.ymthe.2005.06.172
170. In Vitro Transduction of Cells To Determine Tropism Using Viral-Like Particles Derived from JC Virus VP1
Linda Cashion, Oliver Ast, Andrzej Citkowicz, Susan Harvey, Branka Mitrovic, Mary Rose Masikat, Katalin Kauser, Brent Larsen, Gabor M. Rubanyi, Richard N. Harkins and Harald Petry
Mol Ther 11: S68-S68; doi:10.1016/j.ymthe.2005.06.173
171. Changing of Viral Tropism Alters Natural Proviral Property: Implications for Viral Vector Design
Peng H. Tan, Shoa-An Xue, Hans J. Stuass and George J. T. George
Mol Ther 11: S68-S68; doi:10.1016/j.ymthe.2005.06.174
172. In Vitro DNA Packaging and Gene Delivery Using JC Virus-Like Particles
Oliver Ast, Andrezj Citkowicz, Linda Cashion, Brent Larsen, Gabor M. Rubanyi, Richard N. Harkins and Harald Petry
Mol Ther 11: S68-S68; doi:10.1016/j.ymthe.2005.06.175
173. Process Design and Scale-Up of New Vaccine Concepts for Biodefense
Sibylle U. Herzer, Peder Bergvall, Raf Lemmens, Matt Coffey, Walter T. Leps and Peter M. Moore
Mol Ther 11: S69-S69; doi:10.1016/j.ymthe.2005.06.176
174. Process Development of a Scaleable Purification Protocol for the Production of Reolysin, an Oncolytic, Reovirus-Based Therapeutic
Sibylle U. Herzer, Bergvall Peder, Lemmens Raf, Coffey Matt and Moore M. Peter
Mol Ther 11: S69-S69; doi:10.1016/j.ymthe.2005.06.177
175. Titering Gene Delivery Vectors by QPCR: Application to rSV40-Derived Vectors
Christine B. Mitchell and David S. Strayer
Mol Ther 11: S69-S69; doi:10.1016/j.ymthe.2005.06.178
176. Target-Site Preferences of Sleeping Beauty Transposons in an Intron of the B-raf Oncogene
Jason B. Bell, Christopher S. Hackett, Aron M. Geurts, Corey M. Carlson, Lara S. Collier, Geyi Liu, David A. Largaespada and Perry B. Hackett
Mol Ther 11: S69-S70; doi:10.1016/j.ymthe.2005.06.179
177. Analysis of the High Shear Cell Lysis Device and the Air-Mixed Neutralization Column Used in the Recovery of Plasmid DNA from E. coli Cells
Sriram Ramakrishnan, Hugo Gonzalez and Henry L. Hebel
Mol Ther 11: S70-S70; doi:10.1016/j.ymthe.2005.06.180
178. A Novel RNA Quantitation Method Using Hydrophobic Interaction Chromatography-High Performance Liquid Chromatography
Shane Johnson, Andrew Doig, Henry Hebel, Hugo Gonzalez and Heather Attra
Mol Ther 11: S70-S70; doi:10.1016/j.ymthe.2005.06.181
179. Transgenesis of B Lymphocytes by Bacterial DNA Is TLR9 Independent
Mara Gerloni, Matthew Wheeler, Xocthil Cortez-Gonzales, Ilenia Pellicciotta and Maurizio Zanetti
Mol Ther 11: S70-S70; doi:10.1016/j.ymthe.2005.06.182
180. pDNAVACC Vector Family: High Throughput Intracellular Targeting DNA Vaccine Plasmids Created by Gene Self Assembly
James A. Williams, Jeremy Luke, Lance Johnson and Clague P. Hodgson
Mol Ther 11: S70-S71; doi:10.1016/j.ymthe.2005.06.183
181. The Effect of Dissolved Oxygen Fluctuations on Cell Growth and Plasmid Yield
Sriram Ramakrishnan, Justin Miller, Jeffrey Darnell and Henry L. Hebel
Mol Ther 11: S71-S71; doi:10.1016/j.ymthe.2005.06.184
182. An Effective and Valuable Process Using Disposable Membrane-Based Technologies for Pure Plasmid DNA Isolation and Purification: Throughput, Quality, and Cleaning Validation Advantages
Hugo L. Gonzalez, Sriram Ramakrishnan, Shane Johnson, Andrew Doig and Henry L. Hebel
Mol Ther 11: S71-S71; doi:10.1016/j.ymthe.2005.06.185
183. Development of Ex-Vivo Gene Therapy Procedures for Central Nervous System Diseases, Based on Homologous Recombination in Human Neural Stem Cells
Carlos A. Bueno Lopez and Alberto Martinez Serrano
Mol Ther 11: S71-S72; doi:10.1016/j.ymthe.2005.06.186
184. Nonvirally Electrotransfected Human Mesenchymal Stem Cells: A Novel Platform for Bone Gene Therapy Based on Autocrine and Paracrine Mechanisms
Hadi Aslan, Yoram Zilberman, Jin Zhong Li, Gregory A. Helm, Zulma Gazit and Dan Gazit
Mol Ther 11: S72-S72; doi:10.1016/j.ymthe.2005.06.187
185. Poly-lactide-co-glycolide Acid (PLGA) Nanoparticles for DNA Vaccination
Jacob Gvili and Marcelle Machluf
Mol Ther 11: S72-S73; doi:10.1016/j.ymthe.2005.06.188
186. Secreted Extracellular Vesicles of Baculovirus GP64 Interact with Plasmid DNA to Enhance Transfection
Ghiabe H. Guibinga, Andrew C. Hinton, Atsushi Miyanohara and Theodore Friedmann
Mol Ther 11: S73-S73; doi:10.1016/j.ymthe.2005.06.189
187. Strategies of Intravascular Delivery of Naked DNA into Rat Skeletal Muscle
Zhen Jia and Istv|[aacute]|n Dank|[oacute]|
Mol Ther 11: S73-S73; doi:10.1016/j.ymthe.2005.06.190
188. Transfer of DNA in Tissues Using Local Fast Injection
Franck M. Andre, Christel O. Cournil-Henrionnet, Paule Opolon and Lluis M. Mir
Mol Ther 11: S74-S74; doi:10.1016/j.ymthe.2005.06.191
189. Improvement of In-Vivo Transfer of Plasmid DNA in Muscle: Comparison of Electroporation Versus Ultrasound
Geke A. Hospers, Wendy A. Dam, Marc H. DeBaets, Mario H. Losen, Coby Meijer and Nanno H. Mulder
Mol Ther 11: S74-S74; doi:10.1016/j.ymthe.2005.06.192
190. Improvement of Electroporation Devices and Methods for Use with Plasmid-Based Therapeutics and DNA Vaccine Applications in Small and Large Animals
Amir S. Khan and Ruxandra Draghia-Akli
Mol Ther 11: S74-S75; doi:10.1016/j.ymthe.2005.06.193
191. Identification of a Novel Functional Domain in the Sleeping Beauty Transposase: Towards Alleviating the Restriction of SB Overproduction Inhibition
Julie Park, Stephen R. Yant and Mark A. Kay
Mol Ther 11: S75-S75; doi:10.1016/j.ymthe.2005.06.194
192. Non-Viral, Long-Term Gene Expression in Hematopoietic Cells Using the Sleeping Beauty Transposon System
Linda N. Liu, Jeffrey J. Essner, Rama Shivakumar, Linhong Li, Shannon A. Wadman, Karl J. Clark, Aidas Nasevicious, Joseph C. Fratantoni, R. Scott McIvor and Perry B. Hackett
Mol Ther 11: S75-S75; doi:10.1016/j.ymthe.2005.06.195
193. Direct Comparison of Integration Efficiency and Stable Gene Expression Mediated by the Sleeping Beauty Transposon System and by the PhiC31 Phage Integrase System in Cultured Human Fibroblasts and in Various Stem Cell Targets
Andy Wilber, Fernando Montoya, Aron M. Geurts, David A. Largaespada, Uma Lakshmipathy and R. Scott McIvor
Mol Ther 11: S76-S76; doi:10.1016/j.ymthe.2005.06.196
194. Characteristics of Site-Specific Integration as Mediated by PhiC31 Integrase in the Human Genome
Joylette L. Portlock, Thomas W. Chalberg, Eric C. Olivares, Bhaskar Thyagarajan, Patrick J. Kirby and Michele P. Calos
Mol Ther 11: S76-S76; doi:10.1016/j.ymthe.2005.06.197
195. Non-Viral, Site-Specific Gene Transfer into Murine Hematopoietic Stem Cells
Jason J. Hoyt, Annahita Keravala, Jennifer Duda, Chris H. Contag and Michele P. Calos
Mol Ther 11: S76-S77; doi:10.1016/j.ymthe.2005.06.198
196. Role of Kupffer Cells in Hepatic Transgene Expression Mediated by Intrabiliary Infusion of Nonviral Vectors
Hui Dai, Xuan Jiang, Yong Chen, Hai-Quan Mao and Kam W. Leong
Mol Ther 11: S77-S77; doi:10.1016/j.ymthe.2005.06.199
197. Hepatocyte-Specific Delivery of Short Interfering RNAs Using Reducible Polycations
Mark Stevenson, Wei-li Liu, Surjeet Singh, Jon A. Preece, Simon S. Briggs, Uday Tilapur, Martin L. Read and Leonard W. Seymour
Mol Ther 11: S77-S78; doi:10.1016/j.ymthe.2005.06.200
198. Design and Testing of Intrinsic Proteasome Inhibitors To Increase Gene Transfer Efficiency
Molly E. Sinclair, Ji-seon Kim, Changpo Chen, Dijie Liu and Kevin G. Rice
Mol Ther 11: S78-S78; doi:10.1016/j.ymthe.2005.06.201
199. Efficient Inhibition of Bone Metastasis Via Systemic Delivery of siRNA Using Atelocollagen-Mediated Delivery System
Shunji Nagahara, Fumitaka Takeshita, Kimi Honma, Yoshiko Minakuchi, Akihiko Sano and Takahiro Ochiya
Mol Ther 11: S78-S78; doi:10.1016/j.ymthe.2005.06.202
200. Factor VIII Gene Expression after Catheter-Based DNA Nanoparticle Delivery
Katherine Bowman, Xiangying Du, Catherine LeVisage, Rita Sarkar, Xiaoming Yang and Kam W. Leong
Mol Ther 11: S79-S79; doi:10.1016/j.ymthe.2005.06.203
201. C105Y, a Novel Cell Penetrating Peptide Enhances Gene Transfer of Sec-R Targeted Molecular Conjugates
Melanie Rhee and Pamela B. Davis
Mol Ther 11: S79-S79; doi:10.1016/j.ymthe.2005.06.204
202. DNA Delivery to the Mitochondria Sites Using Leader Peptide Conjugated Polyethylenimine
Minhyung Lee, Joon Sig Choi and Kyung Soo Ko
Mol Ther 11: S79-S80; doi:10.1016/j.ymthe.2005.06.205
203. Gene Transfer Activity Is Enhanced Significantly by Allowing Cationic Polymer to Interact with Serum Proteins prior to DNA Addition
Christine C. Conwell, Feng Liu and Leaf Huang
Mol Ther 11: S80-S80; doi:10.1016/j.ymthe.2005.06.206
204. Substrate-Mediated Gene Delivery for Assessment of Signal Transduction Pathways in Cancer Cells
Angela K. Pannier, Zain Bengali, Eric A. Ariazi, V. Craig Jordan and Lonnie D. Shea
Mol Ther 11: S80-S80; doi:10.1016/j.ymthe.2005.06.207
205. Quantitative Analysis of Non-Viral Gene Therapy in a Three-Dimensional Liver Bioreactor
Nathan C. Tedford, Jennifer Fang, Bonnie Huang, Karel Domansky, Linda G. Griffith and Douglas A. Lauffenburger
Mol Ther 11: S81-S81; doi:10.1016/j.ymthe.2005.06.208
206. Intracellular Signal-Responsive Gene Carrier for Cell-Specific Gene Therapy
Yoshiki Katayama, Jeong Hun Kang, Kota Kodama, Jun Oishi and Takuro Niidome
Mol Ther 11: S81-S81; doi:10.1016/j.ymthe.2005.06.209
207. Anti-GAD Antibody Targeted Non-Viral Gene Delivery to Islet Beta Cells
Ji Hoon Jeong, Minhyung Lee, Won Jong Kim, James W. Yockman, Tae Gwan Park, Yong Hee Kim and Sung Wan Kim
Mol Ther 11: S81-S82; doi:10.1016/j.ymthe.2005.06.210
208. Physicochemical and Biological Characterization of Cyclodextrin-Based Polycation (CDP)/siRNA Composites Designed for Systemic Delivery
Derek W. Bartlett, Jeremy D. Heidel and Mark E. Davis
Mol Ther 11: S82-S82; doi:10.1016/j.ymthe.2005.06.211
209. Nuclear Localization Mediated by the Adenoviral-Core Peptide Mu Enhances Phage |[phi]|C31-Integrase Activity in Mammalian Cells
Richard P. Harbottle, Laurence Vaysse, Ahad Rahim, Yvonne Kienast, Ourania Passa, Oleg Tolmachov and Charles Coutelle
Mol Ther 11: S82-S82; doi:10.1016/j.ymthe.2005.06.212
210. Intracellular Disassembly and Transcription Efficiency of Polyplexes Delivered into Cells Using Novel Self-Assembling Gene Carriers
Tetsuji Yamaoka, Tomoko Hashimoto, Tatsuya Kitagawa and Akira Murakami
Mol Ther 11: S82-S83; doi:10.1016/j.ymthe.2005.06.213
211. Novel Fiber-Mediated Adenovirus Interactions in Primary Rabbit Lacrimal Acini
Jiansong Xie, Altan Rentsendorj, Hasmik Agadjanian, Lali K. Medina-Kauwe and Sarah F. Hamm-Alvarez
Mol Ther 11: S83-S83; doi:10.1016/j.ymthe.2005.06.214
212. Differential, Transient Transduction of Defined Human Stem Cell Subsets Using Nanoparticles in a Clinically Applicable Ex Vivo Protocol
Jesper Bonde, Dustin J. Maxwell, David A. Hess, Ryan Lahey, David Piwnica-Worms and Jan A. Nolta
Mol Ther 11: S83-S84; doi:10.1016/j.ymthe.2005.06.215
213. PEG-Modified Cationic Gold Nanoparticles and Their Abilities of In Vivo Gene Delivery
Takahito Kawano, Yasuro Niidome, Yoshiki Katayama and Takuro Niidome
Mol Ther 11: S84-S84; doi:10.1016/j.ymthe.2005.06.216
214. HVJ-E/Importin |[beta]| Hybrid for Efficient Gene Delivery
Takeshi Nagasaki, Takeshi Kawazu and Seiji Shinkai
Mol Ther 11: S84-S84; doi:10.1016/j.ymthe.2005.06.217
215. Investigating Urokinase Plasminogen Activator Receptor (CD87), as a Potential Target for Non-Viral Gene Transfer
Maya Thanou and Thomas Kean
Mol Ther 11: S85-S85; doi:10.1016/j.ymthe.2005.06.218
216. Enhancement of Gene Transfection Both In Vitro and In Vivo Using Polymer Conjugated HVJ-Envelope Vector
Hidetoshi Mima, Ryuji Tomoshige, Yasuhiko Tabata, Seiji Yamamoto, Susumu Ito, Katsuto Tamai and Yasufumi Kaneda
Mol Ther 11: S85-S85; doi:10.1016/j.ymthe.2005.06.219
217. Synthesis and Characterization of a Smart Triblock Copolymer Carrier for siRNA
Tatiana Segura and Jeffrey A. Hubbell
Mol Ther 11: S85-S86; doi:10.1016/j.ymthe.2005.06.220
218. Soluble Flt-1 Gene Delivery Using PEI-g-PEG-RGD Conjugate for Anti-Angiogenesis
Won Jong Kim, James W. Yockman, Minhyung Lee, Ji Hoon Jeong, Yong-Hee Kim and Sung Wan Kim
Mol Ther 11: S86-S86; doi:10.1016/j.ymthe.2005.06.221
219. Development of a Polyethylene Glycol Gene Delivery Vehicle
Nicole M. Kohrt, Lauren E. Grabski and Shelly E. Sakiyama-Elbert
Mol Ther 11: S86-S87; doi:10.1016/j.ymthe.2005.06.222
220. Long-Term Implantation of Photo-Crosslinked Alginate Microcapsules
Feng Shen, Anna A. Li, Murray A. Potter and Patricia L. Chang
Mol Ther 11: S87-S87; doi:10.1016/j.ymthe.2005.06.223
221. Spermine-Grafted Hyaluronic Acid as Multifunctional Coating of the Plasmid/Polycation Complex for Protection, Targeting, and Transcriptional Activation
Tomoko Ito, Naoko Iida-Tanaka, Koji Kubo, Kenichi Yoshikawa and Yoshiyuki Koyama
Mol Ther 11: S87-S88; doi:10.1016/j.ymthe.2005.06.224
222. Enhancement of Intracellular Gene Delivery by the S413-PV Cell Penetrating Peptide
Miguel Mano, Cristina Teod|[oacute]|sio, Artur Paiva, S|[eacute]|rgio Sim|[otilde]|es and Maria C. Pedroso de Lima
Mol Ther 11: S88-S88; doi:10.1016/j.ymthe.2005.06.225
223. In Vitro Gene Transfer from a DNA-PEI Loaded Polylactide-Glycolide Porous Sponge
Garrett R. Rettig, Moses Oyeyumi, Yen-Chen Huang and Kevin G. Rice
Mol Ther 11: S88-S88; doi:10.1016/j.ymthe.2005.06.226
224. Novel Receptor-Mediated Gene Transfection Systems Comprising Plasmid / Polycation / RGD-PEG-COOH Ternary Complexes
Mitsuko Sakae, Tomoko Ito, Naoko Iida Tanaka and Yoshiyuki Koyama
Mol Ther 11: S88-S89; doi:10.1016/j.ymthe.2005.06.227
225. Characterization and Evaluation of Branched and Linear Polyethyleneimine Conjugated PLGA Microparticles for Applications in DNA Vaccine Delivery
Sudhir P. Kasturi, Karishma Sachabhipulkij and Krishnendu Roy
Mol Ther 11: S89-S89; doi:10.1016/j.ymthe.2005.06.228
226. Transcription- Activating Effect of the Synthetic Water-Soluble Polyampholytes
Misa Yamashita, Tomoko Ito, Naoko Iida-Tanaka and Yoshiyuki Koyama
Mol Ther 11: S89-S90; doi:10.1016/j.ymthe.2005.06.229
227. Functionalized Multi-Block Co-Polymers of Short Length Linear Polyethylenimines for Safe and Efficient Gene Transfer
Gregory Slobodkin, Majed Matar, Angela Ramsey, Jason Fewell, Elaine Brunhoeber and Khursheed Anwer
Mol Ther 11: S90-S90; doi:10.1016/j.ymthe.2005.06.230
228. Secretory PTD Fusion Proteins
Paul A. Shaw, Ian R. Catchpole and William H. Colledge
Mol Ther 11: S90-S91; doi:10.1016/j.ymthe.2005.06.231
229. Development of a Novel Drug Delivery System Based on Intrapericardial Administration of Plasmid DNA in a Thermosensitive Gel Formulation
Caroline Roques, Andr|[eacute]| Salmon, Armelle Serose, Elias Fattal and Yves Y. Fromes
Mol Ther 11: S91-S91; doi:10.1016/j.ymthe.2005.06.232
230. The Study on Chitosan Nanoparticles as New Gene Delivery System
Minli Sun, Hao Zhang and Baigen Zhang
Mol Ther 11: S91-S91; doi:10.1016/j.ymthe.2005.06.233
231. Fluorescent Tracking of Non-Viral Gene Delivery
Saeeda Jaffar and Angela Belcher
Mol Ther 11: S91-S91; doi:10.1016/j.ymthe.2005.06.234
232. Gene Therapy for Deficient Cholesterol Synthesis in a Mouse Model of SLOS
Madhavee Buddhikot, Josep Marcos, Dorothy Tabron, Forbes Porter, Cedric Shackleton and Gordon Watson
Mol Ther 11: S91-S92; doi:10.1016/j.ymthe.2005.06.235
233. Towards Reversing Sandhoff Pathology by Lentiviral-Mediated Gene Therapy
Audrey Arfi, Rivka Ziesling, Livia Poenaru, AnthonyH. Futerman and Catherine Caillaud
Mol Ther 11: S92-S92; doi:10.1016/j.ymthe.2005.06.236
234. Polyclonal Insertion Sites in Two Rhesus Macaques after Non-Myeloablative Transplantation with MFGS-gp91phox Transduced Autologous CD34+PBPC
Sebastian Brenner, Martin F. Ryser, Uimook Choi, Narda Whiting-Theobald, Gilda Linton, Elizabeth Kang, Romy Lehmann, Anne M. Farese, Thomas J. MacVittie, Joachim Roesler, Mitchell E. Horwitz and Harry L. Malech
Mol Ther 11: S92-S93; doi:10.1016/j.ymthe.2005.06.237
235. The Route of Vector Delivery Impacts the Therapeutic Effects of AAV-Mediated Gene Therapy in Adult Mucopolysaccharidosis IIIB Mice
Haiyan Fu, Lu Kang, Sheryl S. Moy, Jerillyn S. Jennings, Antonio Perez and Joseph Muenzer
Mol Ther 11: S93-S93; doi:10.1016/j.ymthe.2005.06.238
236. Bone Marrow-Derived Cells Do Not Contribute to Endocrine Pancreas Regeneration in Diabetic RIP/IGF-I Transgenic Mice
Eduard Ayuso, Veronica Jimenez, Judith Agudo, Virginia Haurigot, Jose Carlos Segovia, Juan Bueren and Fatima Bosch
Mol Ther 11: S93-S93; doi:10.1016/j.ymthe.2005.06.239
237. Evaluation of Low-Level, Constitutive Expression of |[beta]|-glucuronidase on the Clinical Manifestations of Mucopolysaccharidosis Type VII
Anthony Donsante, Beth Levy, Carole Vogler and Mark Sands
Mol Ther 11: S93-S94; doi:10.1016/j.ymthe.2005.06.240
238. Stem Cell Gene Delivery to Immunocompetent Mice Using a Non-Myeloablative Regimen Results in Long-Term Transgene Expression and Stable Mixed Chimerism
Brian W. Bigger, Simon N. Waddington, Mamta Buch, Megha Nivsarkar, Nicholas Jones, Suzanne M. Watt, Kathryn Wood and Michael Themis
Mol Ther 11: S94-S94; doi:10.1016/j.ymthe.2005.06.241
239. Immunomodulation Is Necessary to Achieve Stable Expression after Retroviral Vector-Mediated Liver-Directed Gene Therapy to Adult Mice with MPS I
Xiucui Ma, Lingfei Xu, Yuli Liu, Bin Wang and Katherine P. Ponder
Mol Ther 11: S94-S95; doi:10.1016/j.ymthe.2005.06.242
240. Intramuscular Administration of an AAV Vector Expressing 4-Sulfatase (4S) to Newborn Cats With Mucopolysaccaridosis VI: Sulfatase Activity in Muscle, Serum, and Liver
Mark Haskins, Thomas O'Malley, Ping Wang, Karyn Cullen, Anne Traas, Alessandra Tessitore, Monica Doria and Alberto Auricchio
Mol Ther 11: S95-S95; doi:10.1016/j.ymthe.2005.06.243
241. Gene Expression in the Striatum of HPRT Knockout Mice
Song Shaochun and Friedmann Theodore
Mol Ther 11: S95-S95; doi:10.1016/j.ymthe.2005.06.244
242. The Use of AAV Serotype 1 Vector for Expression of |[alpha]|-Galactosidase A in Fabry Knockout Mice
Koichi Ogawa, Yukihiko Hirai, Katsuko Zenri-Aihara, Yoshitaka Fukunaga and Takashi Shimada
Mol Ther 11: S95-S95; doi:10.1016/j.ymthe.2005.06.245
243. Transplantation of Neonatal NOD/SCID/MPSVII Mice with Human Mesenchymal Stem Cells
Phillip E. Herrbrich, Todd E. Meyerrose, Alex A. Hofling, Mark Sands and Jan A. Nolta
Mol Ther 11: S96-S96; doi:10.1016/j.ymthe.2005.06.246
244. AAV Vector-Mediated Gene Therapy of Mucopolysaccharidosis Type I
Lalitha Belur, Damaris Lorenzo, Elena Aronovich, Walter C. Low, Chester B. Whitley and R. Scott McIvor
Mol Ther 11: S96-S96; doi:10.1016/j.ymthe.2005.06.247
245. AAV2/8-Mediated Efficacy and Immune Tolerance in a Pompe Disease Mouse Model
S. D. Bercury, R. J. Ziegler, C. M. Barbon, D. Souza, D. Armentano, B. L. Thurberg, T. Taksir, H. Do, M. Trout, N. Raben and S. H. Cheng
Mol Ther 11: S96-S97; doi:10.1016/j.ymthe.2005.06.248
246. Comparison of rAAV2-Mediated Expression of Human and Murine |[beta]|-Glucuronidase in Adult MPS VII Mice
Kristin C. Greathouse, Chiou-Miin Wang and Thomas J. Sferra
Mol Ther 11: S97-S97; doi:10.1016/j.ymthe.2005.06.249
247. Gene Therapy with a Retroviral Vector Expressing Canine |[beta]|-Glucuronidase to Juvenile (7 Week Old ) Dogs Improves the Biochemical Manifestations of MPS VII
Bin Wang, Ping Wang, Tom O'Malley, Lingfei Xu, Mark E. Haskins and Katherine P. Ponder
Mol Ther 11: S97-S97; doi:10.1016/j.ymthe.2005.06.250
248. A Mouse Model of Type VII Glycogenosis to Assay Gene Therapy Approaches
Fatima Bosch, Miquel Garcia, Anna Pujol, Albert Ruzo, Anna Arbos and Juan E. Feliu
Mol Ther 11: S98-S98; doi:10.1016/j.ymthe.2005.06.251
249. Minimal Dose of AAV8/DC190-ASM Necessary for Therapeutic Efficacy in a Mouse Model of Niemann-Pick Disease
R. J. Ziegler, C. M. Barbon, S. D. Bercury, M. L. Hawes, E. H. Schuchman, R. J. Desnick and S. H. Cheng
Mol Ther 11: S98-S98; doi:10.1016/j.ymthe.2005.06.252
250. Correction of Hunter Syndrome in the Ids-Knock-Out Mouse Model by r-AVV Mediated Gene Therapy
Monica Cardone, Vinicia Polito, Alessandra D'Azzo, Joseph Muenzer, Alberto Auricchio, Andrea Ballabio and Maria Pia Cosma
Mol Ther 11: S98-S99; doi:10.1016/j.ymthe.2005.06.253
251. Dystrophin in Vascular Smooth Muscle Is Important for Duchenne Muscular Dystrophy Therapy
Kaori Ito, Shigemi Kimura, Gail D. Thomas, Shiro Ozasa, Makoto Matsukura, Makoto Ikezawa, Hiroe Ueno, Kowashi Yoshioka, Misao Suzuki, Takeshi Miwa and Teruhisa Miike
Mol Ther 11: S99-S99; doi:10.1016/j.ymthe.2005.06.254
252. A Novel Approach of Gentamicin Therapy for Duchenne Muscular Dystrophy Using Hybrid Liposome and Establishment of a System To Identify the Patients Eligible for the Treatment
Shigemi Kimura, Kaori Ito, Shro Ozasa, Hiroe Kawano, Makoto Ikezawa, Makoto Matsukura, Ryuichi Ueoka, Yoko Matsumoto, Msafumi Matsuo, Yasuhiro Takeshima and Teruhisa Miike
Mol Ther 11: S99-S99; doi:10.1016/j.ymthe.2005.06.255
253. An AAV Vector-Mediated Gene Transfer into Canine Skeletal Muscle
Madoka Ikemoto, Katsutoshi Yuasa, Madoka Yoshimura, Akiyo Nishiyama, Yuko Miyagoe-Suzuki, John McC Howell and Shin'ichi Takeda
Mol Ther 11: S99-S100; doi:10.1016/j.ymthe.2005.06.256
254. Decorin Promotes Differentiation of Myoblasts into Myotubes That Express Slow MyHC In Vitro
Yong Li, Juan Li, Ying Tang, Xiao Xiao and Johnny Huard
Mol Ther 11: S100-S100; doi:10.1016/j.ymthe.2005.06.257
255. Embryonic Stem Cell-Mediated Regenerative Therapy for Duchenne Muscular Dystrophy
Shiro Ozasa, Shigemi Kimura, Makoto Matsukura, Kaori Ito, Makoto Ikezawa, Hiroe Kawano, Teruhisa Miike, Kenichi Yamamura, Kimi Araki, Kuniya Abe and Hitoshi Niwa
Mol Ther 11: S100-S101; doi:10.1016/j.ymthe.2005.06.258
256. An Ideal Therapeutic Agent for Duchenne Muscular Dystrophy Involving a Gutted Adenovirus Expressing Full-Length Utrophin
Jatinderpal R. Deol, Renald Gilbert, Mylene Bourget, Joon-Shik Moon, Josephine Nalbantoglu and George Karpati
Mol Ther 11: S101-S101; doi:10.1016/j.ymthe.2005.06.259
257. Ex Vivo Gene Therapy for Duchenne Muscular Dystrophy: Lentiviral and PhiC31 Integrase Approaches
Simon P. Quenneville, Pierre Chapdelaine, Jo|[euml]|l Rousseau, Michele P. Calos and Jacques P. Tremblay
Mol Ther 11: S101-S101; doi:10.1016/j.ymthe.2005.06.260
258. Identification of Differentially Expressed Genes in Duchenne Muscular Dystropy Utilising RNAi Technology: Possible Targets for Gene Therapy
Mohammad Mahdi Ghahramani Seno, Ian R. Graham, Ken Laing, Marita Pohlschmidt, Takis Athanasopoulos, Mark Crompton and George J. Dickson
Mol Ther 11: S101-S102; doi:10.1016/j.ymthe.2005.06.261
259. Uterine Fibroids Gene Therapy: Adenovirus-Mediated Herpes Simplex Virus Thymidine Kinase/Ganciclovir Treatment Inhibits Growth of Human and Rat Leiomyoma Cells
Ayman Al-Hendy, Marwa Kamel, Gregory Christman and Salama A. Salama
Mol Ther 11: S102-S102; doi:10.1016/j.ymthe.2005.06.262
260. A Database for Managing Neuromuscular Disease Data in the Province of Quebec
Charland Luc, Lavoie Jeremie and Puymirat Jack
Mol Ther 11: S102-S102; doi:10.1016/j.ymthe.2005.06.263
261. Recombinant Adeno-Associated Viral (rAAV) Microdystrophin Vectors as Therapeutic Tools for Duchenne Muscular Dystrophy (DMD)
Takis Athanasopoulos, Ian Graham, Helen Foster, Norma Perez, Adelin Vulin, Vanessa Hill, Stewart Fabb, Luis Garcia, Olivier Danos and George Dickson
Mol Ther 11: S102-S103; doi:10.1016/j.ymthe.2005.06.264
262. Plasmid-Mediated Gene Transfer in mdx Mice Using Mini- and Micro-Dystrophin Constructs
Leland E. Lim, Carmen Bertoni and Thomas A. Rando
Mol Ther 11: S103-S103; doi:10.1016/j.ymthe.2005.06.265
263. Characterization and Gene Transfer in Mesenchymal Stem Cells Derived from Human Umbilical Cord Blood
Feizhou Lu, Jianyuan Jiang, Masayuki Fujino and Xiao-Kang Li
Mol Ther 11: S103-S103; doi:10.1016/j.ymthe.2005.06.266
264. Cell Therapy of Ovarian Failure: Intraovarian Transplanted Granulosa Cells Successfully Engraft and Repopulate Growing Follicles
Ayman Al-Hendy, Hui Q. Wang and Salama A. Salama
Mol Ther 11: S104-S104; doi:10.1016/j.ymthe.2005.06.267
265. Enhanced Plasmid-Mediated Dystrophin Expression in the mdx Mouse Model for Duchenne Muscular Dystrophy by a PhiC31 Integrase Plasmid System
Carmen Bertoni, Sohail Jarrahian, Thurman M. Wheeler, Yining Li, Eric C. Olivares, Michele P. Calos and Thomas A. Rando
Mol Ther 11: S104-S104; doi:10.1016/j.ymthe.2005.06.268
266. Development of rAAV-Based Skeletal and Cardiac Muscle Regulatory Cassettes for Gene Therapy of Duchenne Muscular Dystrophy
Maja Z. Salva, Charis L. Himeda, Phillip Tai, Michael J. Blankinship, Paul Gregorevic, James M. Allen, Leonard A. Meuse, Jeffrey S. Chamberlain and Stephen D. Hauschka
Mol Ther 11: S105-S105; doi:10.1016/j.ymthe.2005.06.269
267. Inflammatory Killing of Normal Cells To Treat Metastatic Tumors
Luis Sanchez-Perez, Gregory Daniels, Timothy Kottke, Rosa Maria Diaz, Atique Ahmed, Jill Thompson, Heung Chong and Richard Vile
Mol Ther 11: S105-S105; doi:10.1016/j.ymthe.2005.06.270
268. Primary Mouse Marrow Stromal Cells Behave as Antigen-Presenting Cells in Syngeneic Immune Responses
John Stagg, Sandra Pommey and Jacques Galipeau
Mol Ther 11: S106-S106; doi:10.1016/j.ymthe.2005.06.271
269. Stimulation of the Immune System Using Gene Therapy Is an Effective Approach for Treating Brain Tumors in Mouse and Rat Models
James F. Curtin, Gwendalyn D. King, Weidong Xiong, Chunyan Liu, PedroR. Lowenstein and MariaG. Castro
Mol Ther 11: S106-S106; doi:10.1016/j.ymthe.2005.06.272
270. Vaccination of Recurrent Glioma Patients with Tumor Lysate-Pulsed Dendritic Cells Elicits Immune Responses: Results of a Clinical Phase I/II Trial
Ryuya Yamanaka, Junpei Homma, Masuhiro Takahashi and Ryuichi Tanaka
Mol Ther 11: S106-S106; doi:10.1016/j.ymthe.2005.06.273
271. Interactions between Replicating Virotherapy and Tumor Growth in the Presence of an Intact Immune System
Michael Forshaw, Caroline Cole, Timothy Kottke, Jill Thompson, Jian Qiao, Peter Selby, Alan Melcher and Richard Vile
Mol Ther 11: S107-S107; doi:10.1016/j.ymthe.2005.06.274
272. Induction of Anti-Tumoral Immune Response and IFN-Regulated Factors by Delivery of Control DNA
Shulin Li, Miles Wilkinson, Xueqing Xia, Michael David and Lihong Xu
Mol Ther 11: S107-S107; doi:10.1016/j.ymthe.2005.06.275
273. Effects of Pre-Existing Immunity on Gene Therapy Mediated by First Generation or High Capacity Adenoviral Vectors Expressing Flt3L in a Syngeneic Glioma Model
Gwendalyn D. King, James F. Curtin, Weidong Xiong, Chunyan Liu, Donna Palmer, Philip Ng, Pedro R. Lowenstein and Maria G. Castro
Mol Ther 11: S107-S108; doi:10.1016/j.ymthe.2005.06.276
274. Genetic Immunotherapy Targeted to Antigen Presenting Cells Using a CD40-Targeted Adenoviral Vector
Disha A. Mody, Larry Smart, Yoshinobu Odaka, Xiao L. Li, Cigdem E. Yilmaz, Alexander V. Pereboev and J. Michael Mathis
Mol Ther 11: S108-S108; doi:10.1016/j.ymthe.2005.06.277
275. RTVP-1 Protein Stimulates Markers of Maturation in Mouse and Human Dendritic Cells
Hongyu Wang, El Moataz Abdelfattah, Salahaldin A. Tahir, Guang Yang, Alexei Goltsov, Weihua Tian, Chengzhen Ren, Chenghui Ren, Terry L. Timme and Timothy C. Thompson
Mol Ther 11: S108-S108; doi:10.1016/j.ymthe.2005.06.278
276. Enhancement of Cytotoxic T-Lymphocyte Responses Against Carcinoembryonic antigen (CEA) Using Genetically Modified Dendritic Cells Expressing CEA and CD40 Ligand
Nachimuthu Chinnasamy, James Neuenfeldt, James Shaffer and Dhanalakshmi Chinnasamy
Mol Ther 11: S109-S109; doi:10.1016/j.ymthe.2005.06.279
277. Large-Scale Generation of Genetically Modified Human CD34+ Progenitor Cell-Derived Langerhans Cells Using a Closed Culture System Suitable for Clinical Immunotherapy
Jianda Yuan, Ryan Kendle, Joanna Hodges, Michel Sadelain, James W. Young and Isabelle Riviere
Mol Ther 11: S109-S110; doi:10.1016/j.ymthe.2005.06.280
278. Induction of Anti-Tumor Activity with Dendritic Cells Loaded with Tumor Cell Lysates or Adenoviral Vector-Encoding Tumor-Associated Antigens
Jae-Gyun Jeong, Hwang-Jae Lee, Hae-Sook Ahn, Sung-Min Oh, Seong-Hyun Ho, Hongchan Cho, Seok Kang, Jong-Mook Kim, Sunyoung Kim and Sujeong Kim
Mol Ther 11: S110-S110; doi:10.1016/j.ymthe.2005.06.281
279. A Novel Functionalized Polymeric Formulation for use in Delivering Therapeutic Genes for the Treatment of Solid Tumors
Jason Fewell, Majed Matar, Jennifer Rice, Gregory Slobodkin, Bruce Hovanes and Khursheed Anwer
Mol Ther 11: S110-S110; doi:10.1016/j.ymthe.2005.06.282
280. Effect of Polysaccharides from Medicinal Herbs as Danger Signals: Implication for Regulating Immune Responses
Chih-Chien Shu, Jeng-Hwan Wang, Su-Jane Wang, Jih-Chun Wen, Wen-Chi Wei, Yi-Fu Yen, Kin-Yuen Cheng, Lie-Fen Shyur and Ning-Sun Yang
Mol Ther 11: S110-S111; doi:10.1016/j.ymthe.2005.06.283
281. Evaluation of Plant Polysaccharides and Phyto-Compounds on Inflammation-Associated Tumorigenesis by Using Melanoma DNA Vaccine Model
Su-Jane Wang, Jeng-Hwan Wang, Wen-Chi Wei, Chih-Chien Shu, Lie-Fen Shyur and Ning-Sun Yang
Mol Ther 11: S111-S111; doi:10.1016/j.ymthe.2005.06.284
282. Effects of Fas Ligand on Inflammation and Tumor Survival Are Dependent on Its Expression Levels
Masatoshi Tagawa, Akihiko Wada, Jiyang O-Wang, Kiyoko Kawamura, Osamu Shimozato, Yuji Tada, Yuichi Takiguchi, Koichiro Tatsumi and Takayuki Kuriyama
Mol Ther 11: S111-S111; doi:10.1016/j.ymthe.2005.06.285
283. Suppression of Inflammatory Pathways Selectively Induced by Oncolytic Viruses Enhances Viral Oncolysis
Giulia Fulci, Laura M. Breymann, Elizabeth J. Fontana, Davide Gianni, Hiroaki Wakimoto, Ralph Weissleder, Robert Lee, Quing Liu and Antonio E. Chiocca
Mol Ther 11: S111-S111; doi:10.1016/j.ymthe.2005.06.286
284. CD137L Gene Transfer Generates Effective and Long-Lasting Immunity in a Murine Plasmocytoma Model
Young Kim, John W. Strehl, Marcus Gorschluter, Carsten Ziske, Christine Mayr and Ingo G.H. Schmidt-Wolf
Mol Ther 11: S111-S112; doi:10.1016/j.ymthe.2005.06.287
285. Anti-Tumor Immune Responses Following Neoadjuvant Immunotherapy with a Recombinant Adenovirus Expressing HSP72 to Rodent Tumors
James A. Krewet, Si-Yi Chen and Maulik R. Shah
Mol Ther 11: S112-S112; doi:10.1016/j.ymthe.2005.06.288
286. Therapeutic Approach Using External Radiation and Suicide Gene Therapy Transduced by Chimeric Adenovirus Vector for Bladder Cancer
Kazumasa Matsumoto, Norihiko Okuno, Bin S. Teh, Christian T.F. Freund, Julie X. Zhu, Maria T. Vlachaki, Alan R. Davis, Brian E. Butler and Seth P. Lerner
Mol Ther 11: S112-S113; doi:10.1016/j.ymthe.2005.06.289
287. mda-7: A Remedy for Oncogene Addiction in Breast Cancer?
Sunil Chada, Yanna Liu, Dora Bocangel, Ming Zheng, Rajagopal Ramesh, Raymond Meyn and Kelly Hunt
Mol Ther 11: S113-S113; doi:10.1016/j.ymthe.2005.06.290
288. A System for GMP Expansion and Transduction of Human T Cells with High Functionality Proven by Consistent Induction of GvHD in a Mouse Xenotransplant Model
Gerhard Bauer, Jon Walker, Bruno Nervi, Julie Ritchey, Jackie Hughes, Bill Eades, Mark Bonyhadi, Jan Nolta and John DiPersio
Mol Ther 11: S113-S113; doi:10.1016/j.ymthe.2005.06.291
289. Highly Inducible and Prostate Specific Oncolytic Adenovirus with E1A-AR Chimera
Ying Li, Chien-Lun Chen, David C. Johns and Ronald Rodriguez
Mol Ther 11: S113-S114; doi:10.1016/j.ymthe.2005.06.292
290. Alpha-Tocopherol Succinate (VES) Enhances Ad-mda7-Mediated Killing of Ovarian Cancer Cells
Manish Shanker, Sunil Chada and Rajagopal Ramesh
Mol Ther 11: S114-S114; doi:10.1016/j.ymthe.2005.06.293
291. Comparison of Anti-Tumor Effects between Transmembrane and Secretory Tumor Necrosis Factor-alpha In Vitro and In Vivo
Wenfang Shi, Qingfen Li and Zhuoya Li
Mol Ther 11: S114-S114; doi:10.1016/j.ymthe.2005.06.294
292. Primary Chronic Lymphocytic Leukaemia Cells Are Resistant to the Oncolytic Effects of Attenuated Measles Virus
Matthew A. Bates, R.G. Wickremasinghe and Adele K. Fielding
Mol Ther 11: S114-S115; doi:10.1016/j.ymthe.2005.06.295
293. Optimizing the Efficacy of Spliceosome-Mediated RNA Trans-Splicing (SMaRT|[trade]|) for Suicide Gene Therapy of Cervical Cancer
Michael Patrick, M. Puttaraju, Janet DiPasquale, Jesse Quintero, Yanping Yang, Mariano A. Garcia-Blanco, Lloyd G. Mitchell, Ed Otto and Carl C. Baker
Mol Ther 11: S115-S115; doi:10.1016/j.ymthe.2005.06.296
294. Adenoviral-TRAIL and a Smac34-8K Fusion Peptide Act Synergistically to Induce Apoptosis in Low CAR-Expressing Human Glioma Cells
Hiroyuki Mushiake, Moira R. Hitchens, Jeffrey C. Mai, Dai-Wu Seol and Paul D. Robbins
Mol Ther 11: S115-S115; doi:10.1016/j.ymthe.2005.06.297
295. Adeno-Associated Virus-Mediated Transfer of the Genes Encoding Cryptic Kringle Fragments of Apolipoprotein (A) Suppresses Tumor Growth and Metastasis In Vivo
Kyuhyun Lee, Sung-Tae Yun and Eui-Cheol Jo
Mol Ther 11: S116-S116; doi:10.1016/j.ymthe.2005.06.298
296. Effective Suppression of Breast Cancer by Downregulation of VEGF Signaling
Yi Lu, Jun Zhang, Derrick J. Beech and Lisa K. Jennings
Mol Ther 11: S116-S116; doi:10.1016/j.ymthe.2005.06.299
297. Radiovirotherapy in Ovarian Cancer Using Recombinant Measles Expressing Sodium Iodide Symporter
Kosei Hasegawa, Hooi-Tin Ong, David Dingli, Takafumi Nakamura, Stephen J. Russell and Kah Whye Peng
Mol Ther 11: S116-S116; doi:10.1016/j.ymthe.2005.06.300
298. Gene Therapy Against Prostate Cancer Using the HSV-tk/Prodrug System Followed by Prostatectomy
Augusto Rojas-Martinez, Laura K. Aguilar, Rocio Ortiz-Lopez, Jacinto Esteban-Maria, Juan F. Gonzalez-Guerrero, Raquel Garza-Guajardo, Juan P. Flores-Gutierrez, E. Brian Butler, Hugo A. Barrera-Saldana and Estuardo Aguilar-Cordova
Mol Ther 11: S116-S117; doi:10.1016/j.ymthe.2005.06.301
299. Increasing Gene Transfer and Oncolytic Potency of Adenoviruses in Orthotopic Models of Gastric Cancer
Lotta Kangasniemi, Anna Kanerva, Mari Raki, Tuuli Ranki, Merja Sarkioja, Tuula Kiviluoto, Ulf-Hakan Stenman, Henrik Alfthan, Hongju Wu, David T. Curiel and Akseli Hemminki
Mol Ther 11: S117-S117; doi:10.1016/j.ymthe.2005.06.302
300. Adenoviral Delivery of the Gene Encoding Secretable Trimeric TRAIL Induces Apoptosis and Suppresses Human Malignant Glioma In Vivo
Moonsup Jeong, In-Ho Kwon, Chae-Young Kim, Dai-Wu Seol, Paul D. Robbins and Byong-Moon Kim
Mol Ther 11: S117-S117; doi:10.1016/j.ymthe.2005.06.303
301. Down-Regulation of bcl-xl Gene Expression with bcl-xl siRNA Vectors In Vitro and In Vivo
Xiaobo X. Cao, Philip Rascoe, Jonathan Daniel, Charles Rodarte and W. Roy Smythe
Mol Ther 11: S117-S118; doi:10.1016/j.ymthe.2005.06.304
302. Herpes Simplex Virus Thymidine Kinase/Ganciclovir Therapy Mediated by Transferrin-Associated Lipoplexes in a Murine Model for Oral Cancer
Silvia S. Neves, Sergio Sim|[otilde]|es and Maria C. Pedroso de Lima
Mol Ther 11: S118-S118; doi:10.1016/j.ymthe.2005.06.305
303. Validating CD46 as a Possible Mechanism Contributing to MV-Edm Oncolytic Specificity
Hooi-Tin Ong, Stephen J. Russell and Kah-Whye Peng
Mol Ther 11: S118-S118; doi:10.1016/j.ymthe.2005.06.306
304. Gene Therapy of Malignant Brain Tumor by a Novel Double-Stranded Adeno-Associated Viral (AAV) Vector Carrying the Decorin Gene
Chi-Hsien Wang, Jun-Ming Han Master, Kai-Yun Chen, Shi-Yuan Cheng, Xiao Xiao and Hsin-I Ma
Mol Ther 11: S118-S119; doi:10.1016/j.ymthe.2005.06.307
305. A Safe TRAIL to Lung Tumor Specificity
Juan Shi, Dexian Zheng, Yanxin Liu, Mai Har Sham, Paul Tam, Farzin Farzaneh and Ruian Xu
Mol Ther 11: S119-S119; doi:10.1016/j.ymthe.2005.06.308
306. A Novel Thymidine Kinase in Enhanced Gap Junction Mediated Suicide Gene Therapy
Tomas J. Ekstrom, Zahidul Khan, Zoran Gojkovic, Mette Willer and Per M. Almqvist
Mol Ther 11: S119-S119; doi:10.1016/j.ymthe.2005.06.309
307. The Tumor-Selective Viral Protein Apoptin Is a Potential Gene Therapeutic Agent for Prostate Cancer Therapy
Xiang Liu, Ahmed El-Zawhry, David Holman, Saeed Elojeimy, Alicja Bielawaska, Jacek Bielawaska, Mahvash Tavassoli and James S. Norris
Mol Ther 11: S119-S120; doi:10.1016/j.ymthe.2005.06.310
308. In Vivo Enhancement of HSV-TK/GCV Cancer Gene Therapy with Polyamine Biosynthesis Inhibition
Tiina Wahlfors, Anne Karppinen, Juhani J|[auml]|nne, Leena Alhonen and Jarmo Wahlfors
Mol Ther 11: S120-S120; doi:10.1016/j.ymthe.2005.06.311
309. STAT5 Phosphorylation in Malignant Melanoma Is Mediated through SRC and JAK-1 Kinases and Exerts Anti-Apoptotic Effects
Alireza Mirmohammadsadegh, Walter Bardenheuer, Mohamad Hassan, Annett Gustrau, Dennis Selimovic, Roya Doroudi, Nicola Schmittner, Sandeep Nambiar, Alessandra Marini, Thomas Ruzicka and Ulrich R. Hengge
Mol Ther 11: S120-S120; doi:10.1016/j.ymthe.2005.06.312
310. Discovered Peptide Mediates Specific Binding to Primary Medullary Thyroid Carcinoma after Systemic Injection
Miriam Bockmann, Gero Hilken, Aaron N. Cranston, Matthias Drosten, Bruce A.J. Ponder, Anke Schmidt and Brigitte M. Putzer
Mol Ther 11: S120-S121; doi:10.1016/j.ymthe.2005.06.313
311. Oncolytic Adenovirus CG5757 Preferentially Infects Primary Human Tumor Tissues and Shows Strong Anti-Tumor Activity in Tumor Models Following Systemic Administration
Yuanhao Li, Trini Arroyo, Stephen Thorne, Tony Reid, Natalie Nguyen, Neeraja Idamakanti, Melinda VanRoey, Gail Colbern and De-Chao Yu
Mol Ther 11: S121-S121; doi:10.1016/j.ymthe.2005.06.314
312. Human Plasminogen Kringle 5-Engineered Murine Mammary Cancer Cells Arrest Tumor Growth and Promote Long-Term Survival
Sabrina R. Perri, Mo|[iuml]|ra Fran|[ccedil]|ois and Jacques Galipeau
Mol Ther 11: S121-S121; doi:10.1016/j.ymthe.2005.06.315
313. Efficacy of Group I Intron-Based Trans-Splicing Ribozyme in Tumor-Targeted Gene Therapy
Byung-Su Kwon, Ju Hyun Kim, Jin-Sook Jeong, In-Hoo Kim and Seong-Wook Lee
Mol Ther 11: S122-S122; doi:10.1016/j.ymthe.2005.06.316
314. The Epithelial Glycoprotein-2 Promoter for Highly Specific and Efficient Cancer Gene Therapy for a Broad Range of Tumors
Willemijn M. Gommans, Gerben Duns, Pamela M.J. McLaughlin, Simone J. van Eert, Masato Yamamoto, David T. Curiel, Hidde J. Haisma and Marianne G. Rots
Mol Ther 11: S122-S122; doi:10.1016/j.ymthe.2005.06.317
315. Highly Specific Expression of the Luciferase Gene in Lungs of Na|[iuml]|ve Nude Mice Directed by Prostate Specific Antigen Promoter
Hongwei Li, Jin Zhong Li, Gregory A. Helm and Dongfeng Pan
Mol Ther 11: S123-S123; doi:10.1016/j.ymthe.2005.06.318
316. Dendritic Cell-Based Genetic Immunotherapy for Prostate Cancer
Briana J. Williams, Nikolay Korokhov, Susan Boling, Linda Li, Michael Mathis and David T. Curiel
Mol Ther 11: S123-S123; doi:10.1016/j.ymthe.2005.06.319
317. Raf-1 siRNA Inhibits Tumor Growth In Vivo
Qixin Leng and A. James Mixson
Mol Ther 11: S123-S123; doi:10.1016/j.ymthe.2005.06.320
318. Tumor Growth Inhibition from Tumor Targeted Delivery of Diphtheria Toxin Gene
Puthupparampil V. Scaria, Qin Zhou, Raymond M. Schiffelers, Aslam Ansari and Martin C. Woodle
Mol Ther 11: S124-S124; doi:10.1016/j.ymthe.2005.06.321
319. ColoAd1, a Chimeric Ad11p/Ad3 Oncolytic Virus for the Treatment of Colon Cancer
Irene Kuhn, Paul Harden, Maxine Bauzon and Terry Hermiston
Mol Ther 11: S124-S124; doi:10.1016/j.ymthe.2005.06.322
320. Antitumor Effect of Intrahepatic Interleukin-12 Expression from a Regulable Plasmid Vector in Murine Models of Primary and Metastatic Liver Cancer
Maider Zabala, Ruben Hernandez-Alcoceba, Margarita Ecay, Ignacio Melero, Christine Perret, Ivan Penuelas, Jesus Prieto and Gabriela M. Kramer
Mol Ther 11: S124-S125; doi:10.1016/j.ymthe.2005.06.323
321. Splice-Switching of the Prostate Specific Membrane Antigen (PSMA) in LnCap Prostate Cancer Cells
Tiffany L. Williams and Ryszard Kole
Mol Ther 11: S125-S125; doi:10.1016/j.ymthe.2005.06.324
322. Tumor Specific Activation of Irinotecan by a Carboxylesterase Fused with Anti CEA scFv
Junji Uchino, koichi Takayama, Tomomichi Sone, akiko Harada, Taishi Harada, David T. Curiel and Yoichi Nakanishi
Mol Ther 11: S125-S125; doi:10.1016/j.ymthe.2005.06.325
323. Transcriptional Targeting of Viral Gene Transfer by Human Hexokinase II Promoter
Ann-Marie Maatta, Sanna Korja, Tanja Hakkarainen, Jarmo Wahlfors, Kimmo M|[auml]|kinen, Esko Alhava and Riikka Pellinen
Mol Ther 11: S125-S125; doi:10.1016/j.ymthe.2005.06.326
324. TRAIL Gene Therapy Is a Promising Therapy for Bladder Cancer
Ahmed M. El-Zawahry and Christina Voelkel-Johnson
Mol Ther 11: S125-S126; doi:10.1016/j.ymthe.2005.06.327
325. Identification of Genes Expressed Specifically in Esophageal Cancer Cells
Fumiaki Sati, John M. Abraham, Jing Yin, Takatsugu Kan, Yuriko Mori and Stephen J. Meltzer
Mol Ther 11: S126-S126; doi:10.1016/j.ymthe.2005.06.328
326. Gene Therapeutic Overexpression of MDR1 Affects Transcriptional Regulations of Proteins Involved in Apoptosis and Detoxification
Patrick Maier, Li Li, Katharina Fleckenstein, Stephanie Laufs, Stefan Fruehauf, Jens Zeller, Frederik Wenz and Carsten Herskind
Mol Ther 11: S126-S126; doi:10.1016/j.ymthe.2005.06.329
327. The Effect of NO on HIF-Mediated Gene Expression: Chemical Sources of NO Versus Genetic Regulation of iNOS
Rana S. Al-Assah, Rachel L. Cowen, Edwin C. Chinje and Ian J. Stratford
Mol Ther 11: S127-S127; doi:10.1016/j.ymthe.2005.06.330
328. An Orthotopic Murine Model of Advanced Breast Cancer for Imaging and Comparison of Targeting Moieties
Tuuli Ranki, Anna Kanerva, Karl von Smitten, Merja Sarkioja, Lotta Kangasniemi, Mari Raki, Pirjo Laakkonen, Hongju Wu, David T. Curiel, Steven Goodison and Akseli Hemminki
Mol Ther 11: S127-S127; doi:10.1016/j.ymthe.2005.06.331
329. Use of Recombinant Non-Pathogenic Bacteria as Vectors for Hypoxia Targeted Gene Expression for Cancer Gene Therapy
Asferd Mengesha, Ludwig Dobois, Brad G. Wouters, Phillipe Lambin and Jan Theys
Mol Ther 11: S127-S128; doi:10.1016/j.ymthe.2005.06.332
330. Lentiviral Vector Mediated Hematopoietic Stem Cell Gene Therapy Combined with Non-Lethal Conditioning Restores T Cell Function in the Murine Model of Wiskott-Aldrich Syndrome
Francesco Marangoni, Lo|[iuml]|c Dupr|[eacute]|, Samantha Scaramuzza, Sara Trifari, Raisa Jofra Hern|[aacute]|ndez, Adrian Thrasher, Anne Galy, Alessandro Aiuti, Luigi Naldini and Maria Grazia Roncarolo
Mol Ther 11: S128-S128; doi:10.1016/j.ymthe.2005.06.333
331. Lentivirus-Mediated Ex Vivo Gene Therapy in ADA-Deficient SCID Mice
Alessandra Mortellaro, Raisa Jofra Hern|[aacute]|ndez, Matteo Guerrini, Antonella Tabucchi, Filippo Carlucci, Antonia Follenzi, Luigi Naldini, Claudio Bordignon, Maria Grazia Roncarolo and Alessandro Aiuti
Mol Ther 11: S128-S129; doi:10.1016/j.ymthe.2005.06.334
332. Chronic Granulomatous Disease Gene Therapy Functionally Corrects the Phenotype of Polymorphonuclear Leukocytes (PMN)
Ulrich Siler, Marion G. Ott, Stefan Stein, Elke Karaus, Maja Rutishauser, Corinne Wenk, Dieter Hoelzer, Manuel Grez and Reinhard Seger
Mol Ther 11: S129-S129; doi:10.1016/j.ymthe.2005.06.335
333. Preferential Targeting of Transcriptional Start Sites after Retroviral-Mediated T-Cell Gene Therapy for Adenosine Deaminase Deficiency
Daniele Moratto, Jayashree G. Jagadeesh, Akihiro Konno, Marita Bosticardo, Gregory E. Crawford, Ingeborg Holt, Linda M. Muul, Shepherd H. Shurman, Tyra Wolfsberg and Fabio Candotti
Mol Ther 11: S129-S129; doi:10.1016/j.ymthe.2005.06.336
334. Treatment of Anemia in Mice with Chronic Renal Failure Utilizing Erythropoietin-Secreting Genetically-Engineered Murine Bone Marrow Stromal Cells
Nicoletta Eliopoulos, Raymonde F. Gagnon, Moira Francois and Jacques Galipeau
Mol Ther 11: S129-S130; doi:10.1016/j.ymthe.2005.06.337
335. Correction of a Murine Model of Von Willebrand Disease by Gene Transfer
Robert G. Pergolizzi, Jin Guang, Diane Chan, Denisa Wagner, Peter Lenting and Ronald G. Crystal
Mol Ther 11: S130-S130; doi:10.1016/j.ymthe.2005.06.338
336. Correction of Chronic Granulomatous Disease by Gene Therapy
Manuel Grez, Marion G. Ott, Stefan Stein, Ulrich Siler, Ulrike Koehl, Hana Kunkel, Andrea Schilz, Klaus Kuehlcke, Dieter Hoelzer and Reinhard Seger
Mol Ther 11: S130-S131; doi:10.1016/j.ymthe.2005.06.339
337. Towards Gene Correction Therapy for Wiskott-Aldrich Syndrome with Engineered Zinc Finger Nucleases
Lei Zhang, Fyodor D. Urnov, Jeffrey C. Miller, Christian Beausejour, Ya-Li Lee, Jeremy Rock, Kenneth Kim, Michael C. Holmes and Philip D. Gregory
Mol Ther 11: S131-S131; doi:10.1016/j.ymthe.2005.06.340
338. Non-Viral Gene Transfer into Hematopoietic Cells of Artemis Deficient ScidA Mice Using the Sleeping BeautyTransposon System
Andy Wilber, Shannon Buckley, Uma Lakshmipathy, Joel Frandsen, Morton J. Cowan and R. Scott McIvor
Mol Ther 11: S131-S131; doi:10.1016/j.ymthe.2005.06.341
339. Long-Term Protein Transduction Domain Mediated Intra-Cellular Delivery of Purine Nucleoside Phosphorylase (PNP) Corrects PNP Deficiency in Mice
Ana Toro and Eyal Grunebaum
Mol Ther 11: S132-S132; doi:10.1016/j.ymthe.2005.06.342
340. Drug-Selectable as Well as Therapeutic Gene Transfer into Hematopoietic Stem Cells May Be Essential in Gene Therapy for Inherited Bleeding Disorders of Large Animals
David A. Wilcox, Juan Fang, Lily M. Du and Mary K. Boudreaux
Mol Ther 11: S132-S132; doi:10.1016/j.ymthe.2005.06.343
341. Lentiviral Vector-Mediated Gene Therapy as Treatment for Wiskott-Aldrich Syndrome (WAS): Pre-Clinical Studies in Human Cell Lines and WASp -/- Mice
S. Humblet-Baron, S. Anover, K. Kipp, Q. Zhu, P. Ye, W. Zhang, Y. Ovechkina, S. Khim, A. Astrakhan, T. Strom, D. Kohn, F. Candotti, Y. Vyas, H. Ochs, C. Miao and D. Rawlings
Mol Ther 11: S133-S133; doi:10.1016/j.ymthe.2005.06.344
342. Human Erythropoietin Gene Therapy for Patients with Chronic Renal Failure
Yitzhak Lippin, Michal Dranitzki-Elhale, Einat Brill-Almon, Chava Mei|[ndash]|Zahav, Sarah Mizrachi, Yael Liberman, Adrian Iaina, Eli Kaplan, Eduardo Podjarny, Nicole Casadevall, Noam Shani and Eithan Galun
Mol Ther 11: S133-S133; doi:10.1016/j.ymthe.2005.06.345
343. Repair of Thalassemic |[beta]|-Globin pre-mRNA by Antisense AAV and Lentiviral Vectors in Cell Culture
Thipparat Suwanmanee, Vivian W. Choi, Richard J. Samulski, Tal Kafri and Ryszard Kole
Mol Ther 11: S133-S134; doi:10.1016/j.ymthe.2005.06.346
344. Application of a suicide Gene to X-SCID Gene Therapy
Toru Uchiyama, Satoru Kumaki, Masahumi Onodera, Du Wei, Looi Chung Yeng, Yoichi Sasahara and Sigeru Tsuchiya
Mol Ther 11: S134-S134; doi:10.1016/j.ymthe.2005.06.347
345. Gene Therapy for Wiskott-Aldrich Syndrome Using Lentiviral Vectors: Evidence for Efficacy and Safety after Transduction of Human T Cells and Hematopoietic Stem Cells
Lo|[iuml]|c Dupr|[eacute]|, Samantha Scaramuzza, Francesco Marangoni, Sara Trifari, Silvana Martino, Shigeru Tsuchiya, Adrian Thrasher, Anne Galy, Luigi Naldini, Alessandro Aiuti and Maria Grazia Roncarolo
Mol Ther 11: S134-S135; doi:10.1016/j.ymthe.2005.06.348
346. Gene Correction of X-Linked SCID Using Engineered Zinc Finger Nucleases and Integration Defective Lentiviral Delivery
Angelo Lombardo, Christian Beausejour, Fyodor D. Urnov, Jeffrey C. Miller, Michael C. Holmes, Philip D. Gregory and Luigi Naldini
Mol Ther 11: S135-S135; doi:10.1016/j.ymthe.2005.06.349
347. Long-Term Gene Expression and Phenotypic Correction of FANCC Deficient Lymphoblastoid Cells Using the Sleeping Beauty Transposon System
Shannon A. Wadman, Karl J. Clark, Perry B. Hackett, R Scott McIvor and Jeffrey J. Essner
Mol Ther 11: S135-S136; doi:10.1016/j.ymthe.2005.06.350
348. Integration Site Analysis of a Helper-Dependent Adenovirus Vector Containing AAV ITRs and 22 kb of the Human Globin LCR
Hongjie Wang, Tobias Leege, Dmitry Shayakhmetov, Qiliang Li, Thalia Papayannopoulou, George Stamatoyannopolous and Andre Lieber
Mol Ther 11: S136-S136; doi:10.1016/j.ymthe.2005.06.351
349. Partial Correction of IL-12 Receptor beta-1 (IL-12Rb1) Deficiency in Mice upon Transplantation of Retrovirally Transduced Hematopoietic Stem Cells
Marita Bosticardo, Charles Scanga, Francesco Novelli, Jean-Laurent Casanova and Fabio Candotti
Mol Ther 11: S136-S136; doi:10.1016/j.ymthe.2005.06.352
350. Pre-Clinical Assays for Cystic Fibrosis Gene Therapy
Uta Griesenbach
Mol Ther 11: S137-S137; doi:10.1016/j.ymthe.2005.06.353
351. Repeat Administration of Polyethylenimine (PEI) Aerosols of Plasmid DNA to the Murine Lung Is Associated with a Loss of Gene Transfer Efficiency
Lee A. Davies, Stephen C. Hyde and Deborah R. Gill
Mol Ther 11: S137-S137; doi:10.1016/j.ymthe.2005.06.354
352. Gene Transfer of Angiogenic Inhibitors Suppresses Lung Tumor Growth in Spontaneous Pulmonary Metastasis Mouse Model
Kexia Cai, Mai Har Sham, Weidong Xiao, Paul Tam and Ruian Xu
Mol Ther 11: S137-S138; doi:10.1016/j.ymthe.2005.06.355
353. Retrovirally-Marked Human Bone Marrow Derived Mesenchymal Stem Cells Attenuate Radiation Induced Pneumonitis in a Xenotransplant Model
Andrew Hope, Todd E. Meyerrose and Jan A. Nolta
Mol Ther 11: S138-S138; doi:10.1016/j.ymthe.2005.06.356
354. Correction of Respiratory Function by Recombinant AAV1 Mediated Gene Therapy in a Murine Model of Glycogen Storage Disease Type II
Cathryn Mah, Kerry O. Cresawn, Lara R. DeRuisseau, David Fuller and Barry J. Byrne
Mol Ther 11: S138-S139; doi:10.1016/j.ymthe.2005.06.357
355. Towards Cystic Fibrosis and Airway Gene Therapy: Evaluation of EGFP Gene Expression in Murine Nasal Airways Mediated by Simian Immunodeficiency Virus Vectors Pseudotyped with Sendai Virus Glycoproteins F and HN
Katsuyuki Mitomo, Makoto Inoue, Yasuji Ueda, Mie Ikegami, Uta Griesenbach, Eric W.F.W. Alton and Mamoru Hasegawa
Mol Ther 11: S139-S139; doi:10.1016/j.ymthe.2005.06.358
356. Sonoporation Increases Non-Viral Gene Transfer to the Murine Lung
Stefania Xenariou, Haidong Liang, Uta Griesenbach, Ray Farley, Luci Somerton, Charanjit Singh, Po-Wah So, Amy Herlihy, Stefano Ferrari, Duncan Geddes, Martin Blomley and Eric Alton
Mol Ther 11: S139-S139; doi:10.1016/j.ymthe.2005.06.359
357. IL-17 Induces Migration of Adult Marrow Stromal Cells to Lung Epithelium
Roberto Loi, Jennifer Jaskolka, Robert Prenovitz, Ying Jian You, Steven Brody and Daniel J. Weiss
Mol Ther 11: S139-S140; doi:10.1016/j.ymthe.2005.06.360
358. Gene Transfer to the Airway Epithelium Mediated by a Third Generation HIV-1 Based Vector: Efficiency and Role of Heparan Sulfate
Elena Copreni, Stefano Castellani, Lucia Palmieri, Salvatore Carrabino, Luigi Naldini and Massimo Conese
Mol Ther 11: S140-S140; doi:10.1016/j.ymthe.2005.06.362
359. Specific Modulation of Tight Junctions to Enhance Airway Gene Transfer
Ruth S. Everett, Miriam K. Vanhook and Larry G. Johnson
Mol Ther 11: S140-S141; doi:10.1016/j.ymthe.2005.06.361
360. Disturbance of Airway Epithelium Is Reduced, Whilst Lentivirus-Mediated Gene Transfer Is Maintained, after Low Dose Lysophosphatidylcholine Pre-Treatment In Vivo
Patricia Cmielewski, Alice G. Stocker, David W. Parsons and Donald S. Anson
Mol Ther 11: S141-S141; doi:10.1016/j.ymthe.2005.06.363
361. Radiation-Induced Lung Apoptosis Is Mediated by TNF-alpha Action
Ming Zhang, Jun Qian, Ming Chen, Spring Kong and Theodore S. Lawrence
Mol Ther 11: S141-S141; doi:10.1016/j.ymthe.2005.06.364
362. Using Real-Time (TaqMan|[reg]|) PCR to Genotype Offspring of Transgenic CF-null Mice |[mdash]| A Core Facility of the UK Cystic Fibrosis Gene Therapy Consortium
Rebecca L. Smith, Lee A. Davies, Hazel Painter, Anusha Varathalingam, Deborah R. Gill and Stephen C. Hyde
Mol Ther 11: S141-S142; doi:10.1016/j.ymthe.2005.06.365
363. Gene Delivery to Human Sweat Glands: A Model for Cystic Fibrosis Gene Therapy
Haeyul Lee, David R. Koehler, Cho Y. Pang, Ronald H. Levine, Philip Ng, Donna J. Palmer, Paul M. Quinton and Jim Hu
Mol Ther 11: S142-S142; doi:10.1016/j.ymthe.2005.06.366
364. Prevention of Radiation Pneumonitis by Recombinant Adenovirus-Mediated Transfer of Soluble TGF-|[beta]|type II Receptor Gene
Koichi Takayama, Haiping Zhang, Junji Uchino, Akiko Harada, Taishi Harada and Yoichi Nakanishi
Mol Ther 11: S142-S142; doi:10.1016/j.ymthe.2005.06.367
365. Aerosol Delivery of an Enhanced Helper-Dependent Adenovirus Formulation to Rabbit Lung Using an Intratracheal Catheter
David R. Koehler, Helena Frndova, Kitty Leung, Emily Louca, Donna Palmer, Philip Ng, Colin McKerlie, Peter Cox, Allan L. Coates and Jim Hu
Mol Ther 11: S142-S142; doi:10.1016/j.ymthe.2005.06.368
366. Development of Quantitative TaqMan RT-PCR for the Evaluation of Non-Viral Mediated Gene Transfer to the Airways
Ian A. Pringle, Rebecca L. Smith, Bryony L. Jones, Deborah R. Gill and Stephen C. Hyde
Mol Ther 11: S142-S143; doi:10.1016/j.ymthe.2005.06.369
367. Safety and Immunological Responses Following Intrapleural Administration of an AAV5 Vector Encoding Human |[alpha]|1-Antitrypsin to Non-Human Primates
Ben-Gary Harvey, Bishnu P. De, John P. Ayala, Neil R. Hackett, Adriana Heguy and Ronald Crystal
Mol Ther 11: S143-S143; doi:10.1016/j.ymthe.2005.06.370
368. Differential Sensitivity of Normal and CML-Derived CD34+Cells to Inhibition of SHP2, Gab2 and Stat5 Gene Expression by RNA Interference (RNAi)
Michaela Scherr, Karin Battmer, Anuhar Chaturvedi, Beate Schultheis, Arnold Ganser and Matthias Eder
Mol Ther 11: S143-S144; doi:10.1016/j.ymthe.2005.06.371
369. Targeted Gene Modification Via Triple Helix-Forming Oligonucleotides
Peter M. Glazer, Faye Rogers and Janice Lloyd
Mol Ther 11: S144-S144; doi:10.1016/j.ymthe.2005.06.372
370. Multi-Copy, Multi-siRNA Vectors as Versatile Tools for Multiple Gene Knock-Down Applications
Laura Poliseno, Monica Evangelista, Mauro Giacca and Giuseppe Rainaldi
Mol Ther 11: S144-S144; doi:10.1016/j.ymthe.2005.06.373
371. Optimizing Custom Zinc-Finger Nucleases for Use in Human Cells
Stephen Alwin, Maja B. Gere, Eva Guhl, Karin Effertz, Carlos F. Barbas III, David J. Segal, Matthew D. Weitzman and Toni Cathomen
Mol Ther 11: S144-S145; doi:10.1016/j.ymthe.2005.06.374
372. Targeting of Non-Viral Vectors to Specific Subnuclear Domains
Joshua Z. Gasiorowski and David A. Dean
Mol Ther 11: S145-S145; doi:10.1016/j.ymthe.2005.06.375
373. Use of Lentiviral and Adeno-Associated Vectors for Targeted Gene Inactivation in Human Cancer Cells
Sabrina Arena, Elisa Vigna, Luigi Naldini and Alberto Bardelli
Mol Ther 11: S145-S145; doi:10.1016/j.ymthe.2005.06.376
374. Knockdown of Shp-2 Expression by siRNA in Mouse Embryonic Stem Cell Derived EB Cells Affects Their Hematopoietic Development
Gang-Ming Zou, Rebecca J. Chan, W. Christopher Shelley and Mervin C. Yoder
Mol Ther 11: S146-S146; doi:10.1016/j.ymthe.2005.06.377
375. Targeted Gene Repair Induces the DNA Damage Response Pathways through the Activation of ATM, and the Stalling of Replication Forks Leading to a Blockage of Inherited Correction
Luciana Ferrara, Julia Engstrom, Erin Brachman, Miya Drury and Eric B. Kmiec
Mol Ther 11: S146-S146; doi:10.1016/j.ymthe.2005.06.378
376. Various Aspects of the Single-Stranded DNA Fragment-Mediated Gene Correction
Hiroyuki Tsuchiya, Hideyoshi Harashima and Hiroyuki Kamiya
Mol Ther 11: S146-S146; doi:10.1016/j.ymthe.2005.06.379
377. Developing siRNAs to the E2Fs to Control Vascular Growth and Remodeling
Paloma H. Giangrande, JianXin Zhang, Juliana Layzer, Otto Hagen, Joseph R. Nevins and Bruce A. Sullenger
Mol Ther 11: S146-S147; doi:10.1016/j.ymthe.2005.06.380
378. Retargeting Mobile Group II Introns to Repair Mutant Genes
Monique N. Kierlin, John P. Jones III, Rob G. Coon, Jiri Perutka, Alan M. Lambowitz and Bruce A. Sullenger
Mol Ther 11: S147-S147; doi:10.1016/j.ymthe.2005.06.381
379. New Zinc Finger Protein Nuclease Architectures for More Efficient Gene Modification Therapies
Jeffrey C. Miller, Lei Zhang, Fyodor D. Urnov, Sarah Patterson, Danny Xia, Jeremy Rock, Sheldon Augustus, Carl O. Pabo, Philip D. Gregory, Edward J. Rebar and Michael C. Holmes
Mol Ther 11: S147-S147; doi:10.1016/j.ymthe.2005.06.382
380. Studies on the Mechanism of Gene Repair Using Saccharomyces cerevisae as a Model System
Katie Maguire, Hetal Parekh-Olmedo and Eric B. Kmiec
Mol Ther 11: S147-S148; doi:10.1016/j.ymthe.2005.06.383
381. Methods for Optimizing Lentiviral Vector-Mediated Gene Suppression by RNA Interference
Eddy Kizana, Genaro Ramirez, Eugenio Cingolani, Roselle Abraham and Eduardo Marban
Mol Ther 11: S148-S148; doi:10.1016/j.ymthe.2005.06.384
382. Expanding the Repertoire of Heterospecific LoxP Sites for Cre-Mediated Site-Specific Recombination
Stephen J. Langer, Jarred Keith and Leslie A. Leinwand
Mol Ther 11: S148-S148; doi:10.1016/j.ymthe.2005.06.385
383. Zinc Finger Nuclease-Boosted Gene Targeting and Synergistic Transient Regenerative Stem Cell Gene Therapy: Toward Clinical Gene Repair/Alteration and Custom Site-Specific Integrative Gene Therapy
Roger Bertolotti
Mol Ther 11: S148-S149; doi:10.1016/j.ymthe.2005.06.386
384. Double-Stranded DNA Breaks Stimulate the Frequency of Targeted Gene Repair in Mammalian Cells
Timothy Schwartz, Luciana Ferrara, Hetal Parekh-Olmedo and Eric B. Kmiec
Mol Ther 11: S149-S149; doi:10.1016/j.ymthe.2005.06.387
385. Gene Correction in the Absence of DNA Repair: A Universal Model Involving Homologous Pairing and DNA Replication
Hetal Parekh-Olmedo, Erin Brachman and Eric B. Kmiec
Mol Ther 11: S149-S149; doi:10.1016/j.ymthe.2005.06.388
386. Large Scale Analysis of Foamy Virus Vector Integration Sites in Human CD34+ Cells
Grant Trobridge, Daniel G. Miller, Michael A. Jacobs, James M. Allen, Erik Olson, Hans-Peter Kiem, Rajinder Kaul and David W. Russell
Mol Ther 11: S149-S149; doi:10.1016/j.ymthe.2005.06.389
387. Myeloid Sarcoma Associated with Gene Marking of Hematopoietic Stem Cells in a Rhesus Macaque
Ruth Seggewiss, Stefania Pittaluga, Rima Adler, Cole Ferguson, Elio F. Vanin, Patrick F. Kelly, Robert E. Donahue, Brian P. Sorrentino, Arthur W. Nienhuis and Cynthia E. Dunbar
Mol Ther 11: S150-S150; doi:10.1016/j.ymthe.2005.06.390
388. Use of the cHS4 Chromatin Insulator to Reduce Oncoretrovirus Vector-Mediated Genotoxicity
David W. Emery, Changlong Li and George Stamatoyannopoulos
Mol Ther 11: S150-S150; doi:10.1016/j.ymthe.2005.06.391
389. Testing the Oncogenic Potential of Retroviral and Lentiviral Vector Integration
Eugenio Montini, Daniela Cesana, Francesca Sanvito, Sergi Sergi Lucia, Benedicenti Fabrizio, Ponzoni Maurilio, Claudio Doglioni and Luigi Naldini
Mol Ther 11: S150-S151; doi:10.1016/j.ymthe.2005.06.392
390. Flanking a Retrovirus Vector with the cHS4 Chromatin Insulator Reduces the Frequency of Vector-Mediated Trans-Activation of Endogenous Genes
Changlong Li and David W. Emery
Mol Ther 11: S151-S151; doi:10.1016/j.ymthe.2005.06.393
391. Effective Gene Therapy with Non-Integrating Lentivirus Vectors
Rafael J. Y|[aacute]||[ntilde]|ez-Mu|[ntilde]|oz, Kamaljit S. Balaggan, Angus MacNeil, Alexander J. Smith, Prateek Buch, Steven Howe, Yana|[iacute]| Dur|[aacute]|n, Robert E. MacLaren, Patrick N. Anderson, Christine Kinnon, Robin R. Ali and Adrian J. Thrasher
Mol Ther 11: S151-S152; doi:10.1016/j.ymthe.2005.06.394
392. Development of a New Lentiviral Vector for Site-Specific Integration into Mammalian Genomes
Angelo Lombardo, Michelle Calos and Luigi Naldini
Mol Ther 11: S152-S152; doi:10.1016/j.ymthe.2005.06.395
393. Site-Directed Integration in Human Genome by Lentiviral Vectors Containing HIV-1 Integrase/Polydactyl Zinc Finger Fusion Proteins
Wenjie Tan, Zheng Dong, Vivian Luo and Samson A. Chow
Mol Ther 11: S152-S152; doi:10.1016/j.ymthe.2005.06.396
394. Oncogenesis Following Delivery of a Non-Primate Lentiviral Gene Therapy Vector to Fetal Mice
Michael Themis, Simon N. Waddington, Manfred Schmidt, Christof von Kalle, Yoahe Wang, Faisal Al-Allaf, Lisa Gregory, Megha Nivsarkar, Matthew Themis, Maxine Holder, Suzanne M.K. Buckley, Niraja Dighe, Alaine Ruthe, Ajay Mistry, Brian Bigger, Adrian J. Thrasher and Charles Coutelle
Mol Ther 11: S152-S153; doi:10.1016/j.ymthe.2005.06.397
395. Safety of In Utero Gene Delivery of Lentiviral Vectors
Susan M. Kingsman, James E. Miskin, Pippa A. Radcliffe, Caroline V. Hacker, Daniel Chipchase, Nicholas D. Mazarakis and Kyriacos A. Mitrophanous
Mol Ther 11: S153-S153; doi:10.1016/j.ymthe.2005.06.398
396. Identification and Characterization of Novel AAV Isolates
Michael K. Schmidt, Emmanuelle Grott, Charles Buck and John A. Chiorini
Mol Ther 11: S153-S153; doi:10.1016/j.ymthe.2005.06.399
397. AAV-Mediated Gene Transfer to Endothelial Cells
Mo-Ying Hsieh, Yi-Lin Liu, Alexander Schlachterman and Katherine A. High
Mol Ther 11: S153-S154; doi:10.1016/j.ymthe.2005.06.400
398. Adeno-Associated Virus Serotype 8 Efficiently Crosses Blood Vessel Barrier in Muscle and Heart for Whole-Body - Delivery
Zhong Wang, Tong Zhu, Chunping Qiao, Liqiao Zhou, Bing Wang, Jian Zhang, Chunlian Chen, Juan Li and Xiao Xiao
Mol Ther 11: S154-S154; doi:10.1016/j.ymthe.2005.06.401
399. rAAV2 Movement Through the Late and Recycling Endosomes Is Influenced by Titer of Infection
Liang Zhang, Wei Ding and John F. Engelhardt
Mol Ther 11: S154-S154; doi:10.1016/j.ymthe.2005.06.402
400. Successful Production of Pseudotyped Mosaic rAAV Vectors Using a Modified Baculovirus Expression System
Erik Kohlbrenner, George Aslanidi, Kevin Nash, Stanislav Shklayev, Martha Campbell-Thompson, Barry J. Byrne, Richard O. Snyder, Nicholas Muzyczka, Kenneth H. Warrington and Sergei Zolotukhin
Mol Ther 11: S155-S155; doi:10.1016/j.ymthe.2005.06.403
401. Evaluation of Primitive Murine Hematopoietic Stem and Progenitor Cell Transduction In Vitro and In Vivo by Recombinant Adeno-Associated Virus Vectors Based on Serotypes 1 through 5
Li Zhong, Weiming Li, Yanjun Li, Keyun Qing, Mervin C. Yoder and Arun Srivastava
Mol Ther 11: S155-S155; doi:10.1016/j.ymthe.2005.06.404
402. Comparison of Pseudotyped rAAV Vectors for Transduction of Primary Hematopoietic Stem and Progenitor Cells Assayed In Vitro and In Vivo
Lijing Li, Sarah Hardy, Leslie Smith-Powell, Sai Srinivas, Stephen J. Forman, K.K. Wong and Saswati Chatterjee
Mol Ther 11: S155-S156; doi:10.1016/j.ymthe.2005.06.405
403. Defined Vector Substrates Used To Probe rAAV DNA Integration
Douglas M. McCarty, Vivian Choi, Alda Fernandes and R.J. Samulski
Mol Ther 11: S156-S156; doi:10.1016/j.ymthe.2005.06.406
404. Roles of Inverted Terminal Repeats (ITRs) and Capsid Proteins from Novel NHP AAVs in rAAV Mediated Gene Transfer
Xiaoyang Zhou, Guangping Gao, Roland A. Owens, You Lu, Roberto Calcedo, Jim Miller and James M. Wilson
Mol Ther 11: S156-S156; doi:10.1016/j.ymthe.2005.06.407
405. Comparison Study of Structural Determinants for AAV Liver Transduction by Domain Swapping between AAV-2 and AAV-8 Capsids
Xuan Shen, Hui Xu, Zan Huang, Theresa A. Storm and Mark A. Kay
Mol Ther 11: S157-S157; doi:10.1016/j.ymthe.2005.06.408
406. Role of MyD88 Signaling Pathway in the Host Immune Responses in Adenoviral Vector-Mediated Gene Therapy
Zhe Zhang, Guang Ping Gao, Lee M. Wetzler, Yan Zhi and James M. Wilson
Mol Ther 11: S157-S157; doi:10.1016/j.ymthe.2005.06.409
407. Complement Blockade Prevents Several Innate Toxicities Rapidly Induced after Intravenous Adenovirus (Ad) Vector Administration
Anne Kiang, Zachary Hartman, Jun-Ping Wei, Ruth Everett, Delila Serra, Haixiang Jiang, Michael M. Frank and Andrea Amalfitano
Mol Ther 11: S157-S158; doi:10.1016/j.ymthe.2005.06.410
408. The Kupffer Cell Scavenger Receptor Is Accountable for Hepatic Sequestration of Adenovirus
Hidde J. Haisma, Anna Rita Bellu, Marianne G. Rots, Gera Kamps, Josee Plantinga and Jan Kamps
Mol Ther 11: S158-S158; doi:10.1016/j.ymthe.2005.06.411
409. Identifying Functional Adenovirus-Host Interactions Using Tandem Mass Spectrometry
Anuj Gaggar, Martin Sadilek, Andre Lieber and Dmitry M. Shayakhmetov
Mol Ther 11: S158-S159; doi:10.1016/j.ymthe.2005.06.412
410. Adenovirus Activates Mouse Platelets and Induces Platelet Leucocyte Association
Maha Othman, Andrea Labelle and David Lillicrap
Mol Ther 11: S159-S159; doi:10.1016/j.ymthe.2005.06.413
411. Trapping of Adenovirus Vectors in Blood
Daniel Stone, Shaoheng Ni, Zong-Yi Li, Dmitry M. Shayakhmetov and Andre Lieber
Mol Ther 11: S159-S159; doi:10.1016/j.ymthe.2005.06.414
412. Renal Pathophysiology after Systemic Administration of a Recombinant Adenovirus: Changes in Drug Metabolism Based upon Vector Dose
Michael P. Boquet, Hong T. Le, Erin A. Clark, Shellie M. Callahan and Maria A. Croyle
Mol Ther 11: S159-S160; doi:10.1016/j.ymthe.2005.06.415
413. Functional Differences of the Reticuloendothelial System in C57BL/6 and Balb/c Mice Mediate Differential Effects of Kuppfer Cell Blockade, Rag-Deficiency and Splenectomy on Transgene Expression after Adenoviral Transfer
Jan Snoeys, Geertrui Mertens, Joke Lievens, D|[eacute]|sir|[eacute]| Collen, Erik Biessen and Bart De Geest
Mol Ther 11: S160-S160; doi:10.1016/j.ymthe.2005.06.416
414. Vitamin B2: A Key Component for Controlled Inactivation of Viruses Suitable for Biological Use
Shellie M. Callahan, Piyanuch Wonganan, Linda J. Obenauer-Kutner, Suganto Sutjipto, Hong T. Le and Maria A. Croyle
Mol Ther 11: S160-S161; doi:10.1016/j.ymthe.2005.06.417
415. Evaluating Polyethylene Glycol (PEG) Modified Adenoviral Vectors for Cell Targeting and Detargeting and Reducing Vector Toxicity
Hoyin Mok and Michael A. Barry
Mol Ther 11: S161-S161; doi:10.1016/j.ymthe.2005.06.418
416. Glucose-Dependent Insulin Production by Liver-Specific, Glucose-Regulatable Synthetic Promoters Results in the Cure of Diabetes
Jaeseok Han, Brienne McLane, Hee-Sook Jun and Ji-Won Yoon
Mol Ther 11: S161-S161; doi:10.1016/j.ymthe.2005.06.419
417. Meganuclease-Mediated Chromosomal Surgery in Living Animals
Agnes Gouble, Julianne Smith, Christophe Perez, Valerie Guyot, Jean-Pierre Cabaniols, Sophie Leduc, Laurence Fiette, Patrick Ave, Beatrice Micheaux, Philippe Duchateau and Frederic Paques
Mol Ther 11: S162-S162; doi:10.1016/j.ymthe.2005.06.420
418. rAAV-Mediated Expression of Adiponectin Receptor (AdipoR2) cDNA in Muscle Prevents the Development of Obesity in DIO Rats
George Aslanidi, Stanislav Shklayev, Erik Kohlbrenner, Vadim Kroutov, Glenn Walter, Martha Campbell-Thompson and Sergei Zolotukhin
Mol Ther 11: S162-S162; doi:10.1016/j.ymthe.2005.06.421
419. Generation of Transgene Product-Specific Regulatory CD4+CD25+ T Cells by Hepatic AAV Gene Transfer
O. Cao, E. Dobrzynski, B.L. Mingle, L. Wang and R.W. Herzog
Mol Ther 11: S162-S163; doi:10.1016/j.ymthe.2005.06.422
420. Tropism-Modified Adeno-Associated Virus Vector Mediates Targeting of Brain Vascular Endothelium In Vivo
Yong Hong Chen and Beverly L. Davidson
Mol Ther 11: S163-S163; doi:10.1016/j.ymthe.2005.06.423
421. Liver Contains Sufficient Sulfatase Modifying Factor for 4-Sulfatase and Correction of MPS VI with Neonatal Retroviral Gene Therapy in Cats
Mark Haskins, Thomas O'Malley, Bin Wang, Jason Metgcalf, Ping Wang, John Hopwood and Katherine P. Ponder
Mol Ther 11: S163-S163; doi:10.1016/j.ymthe.2005.06.472
422. Dominant-Negative Interference in the Pah enu2 Mouse Model of PKU: Effectiveness of Vectors Expressing Either Modified Forms of Phenylalanine Hydroxylase (PAH) or Ribozymes Plus a Hardened PAH mRNA
Catherine E. Charron, O.P. Perera, Stacy L. Porvasnik, Mandy Blackburn, Alfred S. Lewin and Philip J. Laipis
Mol Ther 11: S163-S164; doi:10.1016/j.ymthe.2005.06.424
423. Increased Incidence of Hepatocellular Change and Neoplastic Disease in AAV-WPRE Treated Pah enu2 Mice
Jennifer E. Embury, Catherine E. Charron and Philip J. Laipis
Mol Ther 11: S164-S164; doi:10.1016/j.ymthe.2005.06.425
424. Intracranial AAV5 Synergizes with Non-Myeloablative Bone Marrow Transplantation in the Murine Model of Globoid-Cell Leukodystrophy
Darshong Lin, Anthony Donsante, Shannon Macauley, Beth Levy, Carole Vogler and Mark Sands
Mol Ther 11: S164-S165; doi:10.1016/j.ymthe.2005.06.426
425. AAV2-Mediated Expression of Iduronate Sulfatase in Peripheral Tissues and the CNS in Mucopolysaccharidosis II Mouse Model by Combined Intravenous and Intracisternal Vector Delivery
Lu Kang, Haiyan Fu, Jerillyn S. Jennings and Joseph Muenzer
Mol Ther 11: S165-S165; doi:10.1016/j.ymthe.2005.06.427
426. Cure of Established Disease and Direct Evidence of Cellular Cross-Correction in the Nervous System of Metachromatic Leukodystrophy Mice after HSC-Based Gene Therapy
Alessandra Biffi, Alessia Capotondo, Angelo Quattrini, Ubaldo Del Carro, Riccardo Brambilla, Stefania Fasano, Sergio Marchesini, Claudio Bordignon and Luigi Naldini
Mol Ther 11: S165-S165; doi:10.1016/j.ymthe.2005.06.428
427. AAV2- and AAV5-Mediated CNS Delivery of Human CLN2 Reduces Lysosomal Storage in a Mouse Model of Late Infantile Neuronal Ceroid Lipofuscinosis
Marco A. Passini, Dolan Sondhi, James C. Dodge, Jie Bu, Wendy Yang, Neil R. Hackett, Stephen M. Kaminsky, Mukarram El-Banna, Qinwen Mao, Beverly L. Davidson, David E. Sleat, Peter Lobel, Ronald G. Crystal and Gregory R. Stewart
Mol Ther 11: S166-S166; doi:10.1016/j.ymthe.2005.06.429
428. A Novel Approach for the Treatment of the Neurological Symptoms of MPS VII (Sly Disease)
Brian J. Spencer and Inder M. Verma
Mol Ther 11: S166-S166; doi:10.1016/j.ymthe.2005.06.430
429. AAV5-Mediated Delivery of Human Aryl Sulfatase A (hARSA) Prevents Sufatide Storage and Neuropathological Phenotype in Metachromatic Leukodystrophy (MLD) Mice
Nathalie Cartier, Caroline Sevin, Abdellatif Benraiss, Peter DeDeyn, Delphine Bonnin, Marie-T Vanier, Moullier Philippe, Volkmar Gieselmann and Patrick Aubourg
Mol Ther 11: S166-S167; doi:10.1016/j.ymthe.2005.06.431
430. Immune System Regulation of Transgene Expression from High-Capacity Gutless Adenoviral Vectors in the Mouse Brain: Very Long Term Expression Following Pre-Immunization
Carlos Barcia, Jeffrey M. Zirger, Weidong Xiong, Philip Ng, Donna Palmer, Maria G. Castro and Pedro R. Lowenstein
Mol Ther 11: S167-S167; doi:10.1016/j.ymthe.2005.06.432
431. In Utero CNS Delivery of an Integrating HSV-1 Amplicon Vector Leads to Prolonged, Neuron-Specific Gene Expression
William J. Bowers, Michael A. Mastrangelo, Ann E. Casey, Hilary A. Southerland, Kathleen A. Maguire-Zeiss and Howard J. Federoff
Mol Ther 11: S167-S167; doi:10.1016/j.ymthe.2005.06.433
432. Molecular Chimerism Prevents Experimental Autoimmune Encephalomyelitis (EAE)
Herena Eixarch, Carmen Espejo, Francisco Vidal, Silvia Garces, Mireia Castillo, Alex Bote, Elisabeth Kadar, Marta Rosal, Xavier Montalban and Jordi Barquinero
Mol Ther 11: S167-S168; doi:10.1016/j.ymthe.2005.06.434
433. Gene Therapy of Epilepsy by Adenovirus-Mediated Tetanus Toxin Light Chain Gene Transfer
Jun Yang, Qingshan Teng, Mary E. Garrity-Moses, Thais Federici, Imad Najm, Stephan Chabardes, Michael Moffitt and Nicholas M. Boulis
Mol Ther 11: S168-S168; doi:10.1016/j.ymthe.2005.06.435
434. Long-Term Effects on Retinal Function and Structure Using AAV-Mediated Gene Therapy in Blind RPE65 Null Mutation Dogs
Kristina Narfstrom, Greg Tullis, Ragnheidur Bragadottir, Mathias Seeliger, Elizabeth P. Rakoczy and Martin L. Katz
Mol Ther 11: S168-S168; doi:10.1016/j.ymthe.2005.06.436
435. Functional and Morphological Rescue of the Type I Ocular Albinism Murine Retina Following AAV-Mediated Gene Transfer
Enrico M. Surace, Luciano Domenici, Katia Cortese, Consuelo Venturi, Gabriella Cotugno, Umberto Di Vicino, Alessandro Cellerino, Valeria Marigo, Carlo Tacchetti, Andrea Ballabio and Alberto Auricchio
Mol Ther 11: S169-S169; doi:10.1016/j.ymthe.2005.06.437
436. shRNAs Target HIV-1 Vif Gene Coding for SOCS-Box Motif Prevent Virus Escape from RNA Interference-Mediated Inhibition
Jianfei Ji and John J. Rossi
Mol Ther 11: S169-S169; doi:10.1016/j.ymthe.2005.06.444
437. Alternative Strategies To Deliver Multiple shRNAs in Order to Simultaneously Inhibit Multiple Targets
Peter W. Roelvink, Michael W. Graham, David A. Suhy, Linda B. Couto, Sara M. Cunningham, Mark A. Kay, John J. Rossi and Alexander A. Kolykhalov
Mol Ther 11: S169-S170; doi:10.1016/j.ymthe.2005.06.445
438. Development of an siRNA Based Therapy for Hepatitis Virus Infection
David V. Morrissey, Karin Blanchard, Lucinda Shaw, Kristi Jensen, Wendy Breen, Shawn Zinnen, Brent Dickinson, James A. McSwiggen, Chandra Vargeese, Keith Bowman, Chris S. Shaffer, Lloyd Jeffs, Adam Judge, Barry Polisky, Jennifer A. Lockridge, Amy C.H. Lee and Ian MacLachlan
Mol Ther 11: S170-S170; doi:10.1016/j.ymthe.2005.06.446
439. CXCR4 and CCR5 shRNA Transgenic Macrophages Are Functionally Normal and Resist HIV-1 Infection
Joseph Anderson and Ramesh Akkina
Mol Ther 11: S170-S170; doi:10.1016/j.ymthe.2005.06.447
440. A Non-Human Primate Model for Lentivirus-Mediated Anti-HIV RNAi Strategies
Karen Beagles, Grant Trobridge, Brian Beard, John Rossi, Jiing-Kuan Yee, Shiu-Lok Hu and Hans-Peter KIem
Mol Ther 11: S170-S171; doi:10.1016/j.ymthe.2005.06.448
441. Short Hairpin RNA Interference Expressed from a Gene-Deleted Adenoviral Vector Results in Reduction of Hepatits B Surface Antigen Levels In Vitro and in a Small Animal Model for Hepatitis B Infection
Anja Ehrhardt, Hui Xu, Felix H. Salazar, Patricia L. Marion and Mark A. Kay
Mol Ther 11: S171-S171; doi:10.1016/j.ymthe.2005.06.449
442. Evaluation of siRNA for Induction of In Vitro Resistance in HIV-1
Priscilla Yam, Jerry Wu, Ying Yu, John A. Zaia and Jiing-Kuan Yee
Mol Ther 11: S171-S171; doi:10.1016/j.ymthe.2005.06.450
443. Tissue Specific Expression of Short Hairpin RNAs for the Treatment of HCV Using Liver Specific RNA Pol II Expression Cassettes
David A. Suhy, Alexander A. Kolykhalov, Linda B. Couto, Luz Maria Garcia, A. Rosanna Schroeder, Amy E. Parker, Gabriel Haniff, Sara M. Cunningham, Mark A. Kay and Peter W. Roelvink
Mol Ther 11: S171-S172; doi:10.1016/j.ymthe.2005.06.451
444. A New Vector Which Targets Breast Cancer and Its Vasculature
Yanzheng Liu, Tao Ye, Jonathan Maynard, Hakan Akbulut and Albert Deisseroth
Mol Ther 11: S172-S172; doi:10.1016/j.ymthe.2005.06.452
445. Combinatorial Antiangiogenic Gene Therapy by Nonviral Gene Transfer Using the Sleeping Beauty Transposon Causes Tumor Regression and Improves Survival in Mice Bearing Intracranial Human Glioblastoma
John R. Ohlfest, Zachary L. Demorest, Yasuhiko Motooka, Isabelita Vengco, Seunguk Oh, Eleanor Chen, Frank A. Scappaticci, Stephen C. Ekker, Walter C. Low, Andrew B. Freese and David A. Largaespada
Mol Ther 11: S172-S172; doi:10.1016/j.ymthe.2005.06.453
446. Tie2 Expression Defines an Integrated System of Cell Types Specifically Involved in Angiogenesis, and Provides a Platform for Targeted Gene Delivery to Tumors
Michele De Palma, Mary Anna Venneri, Rossella Galli, Nathalie Belmonte, Maurilio Sampaolesi, Lucia Sergi Sergi and Luigi Naldini
Mol Ther 11: S173-S173; doi:10.1016/j.ymthe.2005.06.454
447. Mesenchymal Stem Cells as Delivery Systems for Cancer Therapy: Evaluation of Tropism and Efficacy
Frank Marini, Jennifer Dembinski, Matus Studeny, Claudia Zompetta and Michael Andreeff
Mol Ther 11: S173-S173; doi:10.1016/j.ymthe.2005.06.455
448. A Genetic Strategy to Inhibit Complement Activation Arising from Adenoviral Vectors
Kurt R. Zinn, Hongju Wu, Amanda Stargel, April J. Adams and Tandra R. Chaudhuri
Mol Ther 11: S173-S174; doi:10.1016/j.ymthe.2005.06.456
449. Tumor Targeted, Systemic Delivery of Therapeutic Viral Vectors Using Hitch Hiking on Antigen Specific T Cells
Jian Qiao, Caroline Cole, Timothy Kottke, Rosa Maria Diaz, Luis Sanchez-Perez, Gregory Brunn, Jill Thompson and Richard Vile
Mol Ther 11: S174-S174; doi:10.1016/j.ymthe.2005.06.457
450. Combination of Fas Gene Therapy and Ceramide Analogues: A Double Edge Sword for the Treatment of Head and Neck Cancer
Saeed N. Elojeimy, John C. McKillop, Ahmed M. El-Zawahry, David A. Schwartz, David H. Holman, Xiang Liu, Terry Day, Alicja Bielawska, Yusuf A. Hannun and James S. Norris
Mol Ther 11: S174-S174; doi:10.1016/j.ymthe.2005.06.458
451. Matrix Metalloproteinase-Targeted Oncolytic Sendai Virus Vector |[ldquo]|Armed|[rdquo]| with a Sucide Gene |[ldquo]|Yeast Cytosine Deaminase|[rdquo]|; Remarkable Combinational Effects
Hiroaki Kinoh, Makoto Inoue, Kentaro Washizawa, Eiji Akiba and Momoru Hasegawa
Mol Ther 11: S175-S175; doi:10.1016/j.ymthe.2005.06.459
452. The Enhancement of Anticancer Effect of Chemotherapy by the Delivery of Rad51 siRNA
Makoto Ito, Seiji Yamamoto, Keisuke Nimura, Katsuto Tamai and Yasufumi Kaneda
Mol Ther 11: S175-S175; doi:10.1016/j.ymthe.2005.06.460
453. The Histone Deacetylase Inhibitor FK228 Can Increase Adenovirus Transgene Protein Expression in Human LOX IMVI Melanoma Xenografts
Merrill E. Goldsmith, Alian Aguila, Michael C. Alley, William R. Waud, Susan Bates and Tito Fojo
Mol Ther 11: S175-S176; doi:10.1016/j.ymthe.2005.06.461
454. Mouse Models for the Analysis of Genetic Risk Factors for Hematopoietic Transformation in XSCID Gene Therapy
Yan Shou, Lilia Stepanova and Brian P. Sorrentino
Mol Ther 11: S176-S176; doi:10.1016/j.ymthe.2005.06.462
455. Drug Resistance Gene Therapy to Induce Donor-Specific Tolerance after Nonmyeloablative Allogeneic Stem Cell Transplantation in Dogs
Sabine Gerull, Karen E. Beagles, Brian C. Beard, Laura J. Peterson and Hans-Peter Kiem
Mol Ther 11: S176-S176; doi:10.1016/j.ymthe.2005.06.463
456. HOXB4 Overexpression Expands Short-Term Repopulating Cells in Nonhuman Primates and Dogs
Xiao-Bing Zhang, Laura J. Peterson, Alixandra A. Knapp, Brian C. Beard, R. Keith Humphries and Hans-Peter Kiem
Mol Ther 11: S177-S177; doi:10.1016/j.ymthe.2005.06.464
457. The Benefits of CH-296 during Ex Vivo Gene Transfer Go beyond the Ability to Co-Localize the Retroviral Particle and Target Cell
Mo A. Dao and Jan A. Nolta
Mol Ther 11: S177-S177; doi:10.1016/j.ymthe.2005.06.465
458. Reversal of Canine Leukocyte Adhesion Deficiency by Retroviral-Vector Mediated Gene Therapy with Non-Myeloablative Conditioning
Thomas R. Bauer Jr., Laura M. Tuschong, Mehreen Hai, Yu-chen Gu, Robert A. Sokolic, Tanya Burkholder, John D. Bacher and Dennis D. Hickstein
Mol Ther 11: S177-S178; doi:10.1016/j.ymthe.2005.06.466
459. Long-Term Treatment of Canine Cyclic Neutropenia by G-CSF-Lentivirus
William Osborne, Margaret Brzezinski, Ofer Yanay, Lanaya Waldon, Jeffrey Christensen, Denny Liggitt and David Dale
Mol Ther 11: S178-S178; doi:10.1016/j.ymthe.2005.06.467
460. Transplantation of Human Aldehyde Dehydrogenase Expressing Cells Leads to Widespread Tissue Distribution of Donor Cells in the Pancreas and Liver of NOD/SCID/MPSVII Mice
David A. Hess, Timothy P. Craft, Louisa Wirthlin, Phillip E. Herrbrich, Alex A. Hofling, Mark S. Sands and Jan A. Nolta
Mol Ther 11: S178-S178; doi:10.1016/j.ymthe.2005.06.468
461. Qualitative and Quantitative Luciferase Expression In Vivo of Transduced Hematopoietic Cell Populations Using Bioluminescent Imaging (BLI)
Henk Rozemuller, Ingrid F.H. Koggel, Robbert Spaapen, Anton Hagenbeek and Anton C.M. Martens
Mol Ther 11: S179-S179; doi:10.1016/j.ymthe.2005.07.001
462. Busulfan Dose Escalation to Increase Gene Marking of Hematopoietic Stem Cells by Lentiviral Vectors in Infant Rhesus Monkeys
Christoph A. Kahl, Alice F. Tarantal, Chang I. Lee, Daniel F. Jimenez, Christopher Choi, Karen Pepper, Denise Peterson, Misty D. Fletcher, Alyssa C. Leapley and Donald B. Kohn
Mol Ther 11: S179-S179; doi:10.1016/j.ymthe.2005.07.002
463. Efficient Lentiviral Gene Transfer and Expression in Human Embryonic Stem Cells
Carolyn Lutzko, XiaoJin Yu, Dinithi Senadheera and Donald B. Kohn
Mol Ther 11: S179-S180; doi:10.1016/j.ymthe.2005.07.003
464. Development of a Novel Gene Regulation System Downstream of Promoter
Hongzhe Duan, Chengwen Li and Richard Jude Samulski
Mol Ther 11: S180-S180; doi:10.1016/j.ymthe.2005.07.004
465. In Vivo Selection of Genetically Modified Primary Human Hematopoietic Cells Using a Cell Growth Switch
Linlin Wang, Yasuo Nagasawa, Brent Wood, Ingrid Lintmaer, Thalia Papayannopoulou, Michael Harkey, Cynthia Nougirat and C. Anthony Blau
Mol Ther 11: S180-S180; doi:10.1016/j.ymthe.2005.07.005
466. Long-Term Rapamycin Control of Transgene Expression in Mouse Salivary Glands in a Single AAV Vector
Jianghua Wang, Antonis Voutetakis, Milton Papa, Victor M. Rivera, Tim Clackson, Beatrijs M. Lodde, Fumi Mineshiba and Bruce J. Baum
Mol Ther 11: S180-S181; doi:10.1016/j.ymthe.2005.07.006
467. Allogeneic Bone-Marrow Transplantation in Mice Provides Tolerance and Promotes Massive In Vivo Selection of Subsequently Transplanted Hepatocytes
Konrad L. Streetz, Regis Doyonnas, Denny D. Jenkins, Seppi Lin, Judith A. Shizuru, Helen Blau, Karl Sylvester and Mark A. Kay
Mol Ther 11: S181-S181; doi:10.1016/j.ymthe.2005.07.007
468. Cellular Therapy with Transgene Expressing APC Activates CD4+CD25+ Regulatory T Cells Which Modulate the Immune Response to Gene Therapy Derived Products in Immunocompetent Mice
Andrea Annoni, Manuela Battaglia, Antonia Follenzi, Angelo Lombardo, Luigi Naldini and Maria Grazia Roncarolo
Mol Ther 11: S181-S182; doi:10.1016/j.ymthe.2005.07.008
469. Induction of Donor Specific Tolerance Using Gene Therapy and Sublethal Conditioning
Daron Forman, Chaorui Tian and John Iacomini
Mol Ther 11: S182-S182; doi:10.1016/j.ymthe.2005.07.009
470. Foamy Viral Mediated Transduction of Recombinant FANCC in the Absence of Prestimulation Is Sufficient To Restore the Long Term Repopulating Activity of Fancc -/- Stem Cells and Prevent the Acquisition of Myeloid Malignancies
Yue Si, Cordula Leurs, Edward F. Srour, Jin Yuan, Helmut Hanenberg and D. Wade Clapp
Mol Ther 11: S182-S182; doi:10.1016/j.ymthe.2005.07.010
471. Microvessel Injury and Irradiation Damage in Salivary Glands
Ana Paola P. Cotrim, Jianghua Wang, Antonis Voutetakis, Anastasia L. Sowers, James B. Mitchell and Bruce J. Baum
Mol Ther 11: S183-S183; doi:10.1016/j.ymthe.2005.07.011
472. Hematopoietic Cell Differentiation from Common Marmoset (Callithrix jacchus) Embryonic Stem Cells by Their Genetic Manipulation Using the Third Generation Lentiviral Vector
Tomoko Yokoo, Ryo Kurita, Erika Sasaki, Takashi Hiroyama, Yukoh Nakazaki, Kiyoko Izawa, Hajime Ishii, Yoshikuni Tanioka, Kisaburo Hanazawa, Yuan Son Bai, Yasushi Soda and Kenzaburo Tani
Mol Ther 11: S183-S183; doi:10.1016/j.ymthe.2005.07.012
473. Definitive Identification and Isolation of Embryonic Stem Cell-Derived Target Cells by Adenoviral Conditional Targeting; Efficient Purification of Immature and Mature Cells in the Cardiac Lineage
Ken-ichiro Kosai and Tomoyuki Takahashi
Mol Ther 11: S183-S184; doi:10.1016/j.ymthe.2005.07.013
474. Transduction of Minimally Stimulated Hematopoietic Progenitor Cells with a Foamy Virus Vector That Expresses MGMTP140K
Shanbao Cai, Jennifer R. Hartwell, Aaron G. Ernstberger, W.S. Goebel, Helmut Hanenberg and Karen E. Pollok
Mol Ther 11: S184-S184; doi:10.1016/j.ymthe.2005.07.014
475. In Vivo Targeting of MLV(HIV) Pseudotype Vectors to T Lymphocytes in a Transgenic Mouse Model
Silke Schuele, Stefanie Steidl, Sylvia Raupp, Cheick Coulibaly, Ulrich Kalinke, Klaus Cichutek and Matthias Schweizer
Mol Ther 11: S184-S185; doi:10.1016/j.ymthe.2005.07.015
476. HIV-1 and HIV-2 Chimeric Lentiviral Vectors for Gene Transfer
Geetanjali Sachdeva, Kritika Kachapati and Suresh Arya
Mol Ther 11: S185-S185; doi:10.1016/j.ymthe.2005.07.016
477. Development of SIV Based Vectors with Efficient Delivery for Vector Dynamic Studies in the Simian System
Christopher Chen, Jiamo Lu, Tatiana Slepushkina, Andrew Worden, Vladimir Slepushkin, Laurent M. Humeau, Gwendolyn K. Binder and Xiaobin Lu
Mol Ther 11: S185-S185; doi:10.1016/j.ymthe.2005.07.017
478. A HIV-1 Based Cross-Packaging System for FIV Vectors
Adam S. Cockrell, Hong Ma, Thomas McCown, Kim D. Kluckman, Randy J. Thresher and Tal Kafri
Mol Ther 11: S185-S186; doi:10.1016/j.ymthe.2005.07.018
479. Targeted Entry of Retroviral Vectors Depends on Characteristics of the Target Receptor and the Chimeric Envelope Protein
LorraineM. Albritton, Fang Li, Pankaj Kumar and Langzhu Tan
Mol Ther 11: S186-S186; doi:10.1016/j.ymthe.2005.07.019
480. Examination of the Relationship between the Level of Gene Transfer and the Number of Envelope Proteins That Are Incorporated Per Retrovirus Particle When High Doses of Purified Virus Stocks Are Used to Transduce Cells
Natalia Land|[aacute]|zuri and Joseph M. Le Doux
Mol Ther 11: S186-S186; doi:10.1016/j.ymthe.2005.07.020
481. Dynamics of Transduction of Human Cells by EIAV Vectors |[ndash]| The Importance of Cell Entry
Daniel C. Farley, Fraser J. Wilkes, James E. Miskin, Susan M. Kingsman and Kyriacos A. Mitrophanous
Mol Ther 11: S186-S187; doi:10.1016/j.ymthe.2005.07.021
482. Neuronal Gene Transfer with HIV-1-Based Lentiviral Vectors Pseudotyped with Lyssavirus Glycoproteins
Qingshan Teng, Mary E. Garrity-Moses, Thais Federici, Jun Yang, Robert Kutner, Noel Tordo, Jakob Reiser and Nicholas M. Boulis
Mol Ther 11: S187-S187; doi:10.1016/j.ymthe.2005.07.022
483. Targeted Receptor Trafficking Affects the Efficiency of Retrovirus Transduction
Delfi Krishna, Julia Raykin and Joseph Le Doux
Mol Ther 11: S187-S187; doi:10.1016/j.ymthe.2005.07.023
484. Ultrasound-Mediated Microbubble Destruction and Retroviral Gene Delivery
Sarah L. Taylor, Ahad Rahim, Nigel Bush, Jeff Bamber and Colin Porter
Mol Ther 11: S188-S188; doi:10.1016/j.ymthe.2005.07.024
485. Lentivirus-Mediated Gene Transfer to Cultured Fetal Sheep Airway Epithelium and Lung Tissue Explants
Ze-Yan Yu, Karen McKay, Peter Van Asperen, Maolin Zheng, Jane Fleming, Samantha Ginn, Eugenie Lumbers, Peter Rowe and Ian Alexander
Mol Ther 11: S188-S188; doi:10.1016/j.ymthe.2005.07.025
486. Optimized Conditions for Retroviral Gene Transfer by RetroNectin|[reg]| Bound Virus Infection Method
Hideto Chono, Hiromi Okuyama, Yasushi Katayama, Nobuto Koyama, Junichi Mineno, Kiyozo Asada and Ikunoshin Kato
Mol Ther 11: S189-S189; doi:10.1016/j.ymthe.2005.07.026
487. Enhancement of Adeno- and Lentivirus Mediated Gene Transfer in Human Tumor Cell Lines by Cell Permeable Peptides and Polycations
Saara Lehmusvaara, Outi Meril|[auml]|inen, Tanja Hakkarainen and Jarmo Wahlfors
Mol Ther 11: S189-S189; doi:10.1016/j.ymthe.2005.07.027
488. Engineering Enhanced Retroviral Vectors through the Insertion of a His6 Tag into VSV-G
Julie H. Yu and David V. Schaffer
Mol Ther 11: S189-S189; doi:10.1016/j.ymthe.2005.07.028
489. Further Studies of the Most Efficient Vector Systems for Gene Transduction into Human Dendritic Cells Line (im-NMD)
Eigo Sato, Masanari Kato, Yuko Hara, Hua Yan, Tohko Miyagi, Xiao-Kang Li, Wataru Sugiura, Naoki Yamamoto, Kenichi Teramoto, Shigeki Arii and Hiromitsu Kimura
Mol Ther 11: S190-S190; doi:10.1016/j.ymthe.2005.07.029
490. Lentiviral-Mediated Gene Transfer to Cells of the Vasculature
Ciara A. O'Shea, Robert J. Nelson, Padraig Strappe and Timothy O'Brien
Mol Ther 11: S190-S190; doi:10.1016/j.ymthe.2005.07.030
491. Development of Fast and Efficient Methods for the Purification and Concentration of Lentiviral Vectors
Rachel M. Koldej and Donald S. Anson
Mol Ther 11: S190-S190; doi:10.1016/j.ymthe.2005.07.031
492. Harvest Timing and Media Composition Effects on Lentiviral Vector Production
Christopher Ballas, Terry Johnson and Kenneth Cornetta
Mol Ther 11: S191-S191; doi:10.1016/j.ymthe.2005.07.032
493. Concentration and Purification of Lentivirus Pseudotypes Bearing Alternative Envelope Glycoproteins
Robert H. Kutner and Jakob Reiser
Mol Ther 11: S191-S191; doi:10.1016/j.ymthe.2005.07.033
494. Assessing Lentiviral Vector Quality Using Transmission Electron Microscopy
Lakshmi Sastry, Carole Miller, Terry Johnson, Aparna Jasti, Vince Gattone and Kenneth Cornetta
Mol Ther 11: S191-S192; doi:10.1016/j.ymthe.2005.07.034
495. Upscaling of Retroviral Vector Production under GMP Guidelines to Generate High Titer Preparations for Clinical Use
Sandra Jung, Peter Leyendecker, Frank Kogelberg, Christian Wolf, Andrea Schilz, Klaus Kuehlcke and Sonja Naundorf
Mol Ther 11: S192-S192; doi:10.1016/j.ymthe.2005.07.035
496. Stability of Oncolytic Measles Viruses during Storage and Clinical Preparation
Troy R. Wegman, Kirsten K. Langfield, Henry J. Walker, Guy E. Griesmann, Julie A. Sauer, Sharon A. Stephan and Mark J. Federspiel
Mol Ther 11: S192-S192; doi:10.1016/j.ymthe.2005.07.036
497. Sex and Estrous Cycle Stage Influence the Efficiency of AAV-Mediated Gene Transfer in the Rodent Brain
James C. Dodge, Jennifer Clarke, Marco A. Passini, Anthony Song, Catherine R. O'Riordan, Seng H. Cheng and Gregory R. Stewart
Mol Ther 11: S192-S193; doi:10.1016/j.ymthe.2005.07.037
498. Adeno-Associated Virus Type-1 Vectors Efficiently Transduce Human Polarized Airway Epithelia without Polarity Bias
Ziying Yan, Xiaoming Liu, Chi-Man Lei, Meihui Luo and John F. Engelhardt
Mol Ther 11: S193-S193; doi:10.1016/j.ymthe.2005.07.038
499. Species-Specific Differences in the Polarity of rAAV5 and rAAV2 Transduction of Mouse and Human Airway Epithelia
Xiaoming Liu, Ziying Yan, Meihui Luo and John F. Engelhardt
Mol Ther 11: S193-S193; doi:10.1016/j.ymthe.2005.07.039
500. Biology of Novel AAV Serotype Vectors in the Liver Directed Gene Transfer to Nonhuman Primates
Guangping Gao, You Lu, Roberto Calcedo, Rebecca Grant, Julio Sanmiguel, Lili Wang, Julie Johnston, Joanita Figueredo, Martin Lock and James M. Wilson
Mol Ther 11: S194-S194; doi:10.1016/j.ymthe.2005.07.040
501. AAV6 Pseudotyped Double-Stranded-AAV Vectors Allow Adenoviral-Like Transduction and Brute-Force Integration in the Growing Mouse
Ognjen Petras, Timothy J. Davern, Marcus O. Muench and Xiaodong Han
Mol Ther 11: S194-S194; doi:10.1016/j.ymthe.2005.07.041
502. GFP-Tagged Adeno-Associated Viral (AAV) Particles Allow the Study of Cytosolic and Nuclear Trafficking
Kerstin Lux, Stefanie Schlemminger, Luca Perabo, Daniela Goldnau, Jan Endell, Michael Hallek and Hildegard Buening
Mol Ther 11: S195-S195; doi:10.1016/j.ymthe.2005.07.042
503. Mutational Strategy To Enhance or Rescue Functionality of Existing AAV Vectors
Luk H. Vandenberghe, Michael H. Yang, Julie Johnston, Guangping Gao and James M. Wilson
Mol Ther 11: S195-S195; doi:10.1016/j.ymthe.2005.07.043
504. In Vivo Characterization of AAV Serotype 9 Vectors in Mice
Katsuya Inagaki, Theresa A. Storm, Sally Fuess, Mark A. Kay and Hiroyuki Nakai
Mol Ther 11: S195-S196; doi:10.1016/j.ymthe.2005.07.044
505. Analysis of AAV Genome Conversion and Stabilization
Bernd Hauck, Jing Xie and Weidong Xiao
Mol Ther 11: S196-S196; doi:10.1016/j.ymthe.2005.07.045
506. Transductional and Genome Biodistribution of Novel AAV Serotype Vectors after Systemic Delivery and Their Liver Specific Dose Response Profiles in Mice
You Lu, Guangping Gao, Julio Sanmiguel, Roberto Calcedo, Peter Bell, Nelson Wivel and James M. Wilson
Mol Ther 11: S196-S196; doi:10.1016/j.ymthe.2005.07.046
507. Modeling Adeno-Associated Virus 2 Capsid for the Identification of Targeting Ligands for Enhanced Gene Transfer to Polarized Human Airway Epithelial Cells
April F. White, Marina Mazur, Eric J. Sorscher and Selvarangan Ponnazhagan
Mol Ther 11: S197-S197; doi:10.1016/j.ymthe.2005.07.047
508. Impact of Sex on Serum |[alpha]|1-Antitrypsin Levels Following Intrapleural and Intravenous Administration of AAVrh.10 Vectors to Mice
Bishnu P. De, Adriana Heguy, Neil R. Hackett, Guangping Gao, James M. Wilson and Ronald G. Crystal
Mol Ther 11: S197-S197; doi:10.1016/j.ymthe.2005.07.048
509. Endogenous Estradiol Augments RGD Modified AAV2-Mediated Gene Transfer in Human Ovarian Epithelial Cancer
Wenfang Shi and Jeffery Bartlett
Mol Ther 11: S197-S198; doi:10.1016/j.ymthe.2005.07.049
510. Neonatal Gene Transfer with Non-Human Primate AAV Vector Serotypes Results in Widespread Transduction and Gene Activity in the Mouse Brain
Brian A. Karolewski, Hennessy Howell and John H. Wolfe
Mol Ther 11: S198-S198; doi:10.1016/j.ymthe.2005.07.050
511. Effect of Hepatocyte Division on Molecular Fate of rAAV DNA
Young-Kook Choi, Yuanqing Lu and Sihong Song
Mol Ther 11: S198-S198; doi:10.1016/j.ymthe.2005.07.051
512. The Cellular TATA-Binding Protein Is Required for Replication of a Minimal Adeno-Associated Virus Type 2 (AAV-2) p5 Promoter Element
Achille Fran|[ccedil]|ois, Mickael Guilbaud, Rafi Awedikian, Gilliane Chadeuf, Philippe Moullier and Anna Salvetti
Mol Ther 11: S198-S199; doi:10.1016/j.ymthe.2005.07.052
513. Novel Characteristics of Heparin Binding by Adeno-Associated Virus Serotype 6
James M. Allen, Eric E. Finn and Jeffrey S. Chamberlain
Mol Ther 11: S199-S199; doi:10.1016/j.ymthe.2005.07.053
514. Effect of DNA-PKcs on AAV Replication
Young-Kook Choi, Irene Zolotukhin, Barry J. Byrne and Sihong Song
Mol Ther 11: S199-S199; doi:10.1016/j.ymthe.2005.07.054
515. Overlapping Adeno-Associated Viral (AAV) Vector Mediated Gene Transfer Is Dependent on Viral Serotype and the Transgene Sequence in Skeletal Muscle
Arkasubhra Ghosh, Yongping Yue and Dongsheng Duan
Mol Ther 11: S199-S199; doi:10.1016/j.ymthe.2005.07.055
516. Analysis of AAV Serotype 8 Vector Integration in Normal and DNA-PKcs-Deficient Scid Mice by a Novel Strategy
Katsuya Inagaki, Xiaolin Wu, Sally Fuess, Theresa A. Storm, Mark A. Kay and Hiroyuki Nakai
Mol Ther 11: S200-S200; doi:10.1016/j.ymthe.2005.07.056
517. Type 1 Rep52 Is Superior to Authentic Rep52 for Producing Recombinant Adeno-Associated Virus Type 5 in Insect Cells
Masashi Urabe, Takayo Nakakura, Hiroaki Mizukami, Akihiro Kume, Robert M. Kotin and Keiya Ozawa
Mol Ther 11: S200-S200; doi:10.1016/j.ymthe.2005.07.057
518. Production of Recombinant Type 2 Adeno-Associated Virus in Bioreactors
Yves Durocher, Phuong Lan Pham, Gilles St-Laurent, Danielle Jacob, Brian Cass, Josephine Nalbantoglu and Amine Kamen
Mol Ther 11: S200-S201; doi:10.1016/j.ymthe.2005.07.058
519. Selective Inactivation of Helper Adenovirus with High Hydrostatic Pressure for AAV-2 Vector Production
Joshua N. Leonard, David V. Schaffer, Peter Ferstl and Antonio Delgado
Mol Ther 11: S201-S201; doi:10.1016/j.ymthe.2005.07.059
520. The Effects of Transgene and Cassette Size on Recombinant AAV2 Production and Expression
Corinne M. Goldsmith, Antonis Voutetakis and Bruce J. Baum
Mol Ther 11: S201-S201; doi:10.1016/j.ymthe.2005.07.060
521. Spliceosome-Mediated RNA Trans-Splicing with rAAV Partially Restores CFTR Function to Polarized Human CF Airway Epithelial Cells
Xiaoming Liu, Meihui Luo, Liang N. Zhang, Ziying Yan, Wei Ding, Roman Zak, Gary S. Mansfield, Lloyd G. Mitchell and John F. Engelhardt
Mol Ther 11: S201-S202; doi:10.1016/j.ymthe.2005.07.061
522. Enhanced Repair of Articular Cartilage Defects in Rabbits by Overexpression of Human FGF-2 Via rAAV-Mediated Gene Transfer
Magali Cucchiarini, Henning Madry, Chunyan Ma, Tanja Thurn, David Zurakowski, Dieter Kohn, Michael D. Menger, Stephen B. Trippel and Ernest F. Terwilliger
Mol Ther 11: S202-S202; doi:10.1016/j.ymthe.2005.07.062
523. AAV Transcytosis through Barrier Epithelia and Endothelium
Giovanni Di Pasquale and John A. Chiorini
Mol Ther 11: S202-S202; doi:10.1016/j.ymthe.2005.07.063
524. Adenovirus-Mediated Gene Delivery of Decoy Death Receptors Protects Mice from Hepatitis
Delphyne Descamps, Fr|[eacute]|d|[eacute]|ric Vigant, St|[eacute]|phanie Esselin, Elisabeth Connault, Paule Opolon, Michel Perricaudet and Karim Benihoud
Mol Ther 11: S202-S203; doi:10.1016/j.ymthe.2005.07.064
525. Optimized Gene Transfer into Mesenchymal Stem Cells and Embryonic Stem Cells by Modified Adenovirus Vectors
Hiroyuki Mizuguchi, Kenji Kawabata, Fuminori Sakurai, Tomomi Sasaki, Teruhide Yamaguchi and Takao Hayakawa
Mol Ther 11: S203-S203; doi:10.1016/j.ymthe.2005.07.065
526. Conditionally Replicative Adenoviruses Designed to Restore Defects in the p53 Pathway for Effective Virotherapy of Cancer
Victor W. van Beusechem, Danielle A.M. Heideman, Jan E. Carette, Martin Scheffner, Ramon Alemany and Winald R. Gerritsen
Mol Ther 11: S203-S204; doi:10.1016/j.ymthe.2005.07.066
527. Reductions in Tissue Transduction and Toxicity after Systemic Administration of Adenovirus Vectors Containing Fiber-Shaft Exchange in Combination with both CAR- and av Integrin-Binding Ablation
Naoya Koizumi, Hiroyuki Mizuguchi, Kenji Kawabata, Fuminori Sakurai, Yoshiteru Watanabe and Takao Hayakawa
Mol Ther 11: S204-S204; doi:10.1016/j.ymthe.2005.07.067
528. Infectivity Enhancement of a Genetic Fiber Mosaic Adenovirus Vector in Ovarian Cancer Cells
Yuko Tsuruta, Larisa Pereboeva, Joel N. Glasgow, Yosuke Kawakami and David T. Curiel
Mol Ther 11: S204-S204; doi:10.1016/j.ymthe.2005.07.068
529. Oncolytic Virotherapy Employing flt-1 Driven mda-7/IL-24 Gene Delivery
Sergey A. Kaliberov, Lyudmila N. Kaliberova, Amy S. Petersen, Valentina Krendelchtchikova, Victor Krasnykh and Donald J. Buchsbaum
Mol Ther 11: S204-S205; doi:10.1016/j.ymthe.2005.07.069
530. Adenoviral and Hydrodynamic Gene Transfer of Replicating Episomes Result in Stable Transgene Expression after Partial Hepatectomy in Mice
Jan Snoeys, D|[eacute]|sir|[eacute]| Collen and Bart De Geest
Mol Ther 11: S205-S205; doi:10.1016/j.ymthe.2005.07.070
531. Balloon Catheter-Mediated Hepatic Vein Delivery of a Viral Vector Mitigates Neutralization by Anti-Viral Antibodies and Results in Efficient Transduction of Rabbit Liver
Bradley L. Hodges, Kristin M. Taylor, Qiuming Chu, Samantha E. Scull, Rebecca G. Serriello, Scott C. Anderson and Ronald K. Scheule
Mol Ther 11: S205-S206; doi:10.1016/j.ymthe.2005.07.071
532. Effects of a New YB-1 Dependent Adenovirus (XVir) in Human Prostate Cancer Cell Lines and in a Xenograft Mouse Model
Klaus Mantwill, Nadia Koehler-Vargas, Alexandra Bernshausen, Uwe Treiber, Rudolf Hartung, Bernd Gansbacher and Per Sonne Holm
Mol Ther 11: S206-S206; doi:10.1016/j.ymthe.2005.07.072
533. Enhanced Transduction of Dendritic Cells by FCgRI-Targeted Adenovirus Vectors|[gamma]|
Ramil E. Sapinoro, Angela P.H. Burgess and Stephen Dewhurst
Mol Ther 11: S206-S206; doi:10.1016/j.ymthe.2005.07.073
534. Optimising Expression Cassettes for Vascular Gene Expression
Stephen J. White, Melanie A. Roberts, Jeremy R. Sanford, Javier F. C|[aacute]|ceres and Andrew C. Newby
Mol Ther 11: S206-S207; doi:10.1016/j.ymthe.2005.07.074
535. Long-Term Correction of Hyperbilirubinemia in a Rat Model of Crigler-Najjar Syndrome Type 1
Viraj P. Mane, Gabriele Toietta, Wilma Norona, Milton Finegold, Phil Ng, Arthur L. Beaudet, Anthony F. McDonagh and Brendan Lee
Mol Ther 11: S207-S207; doi:10.1016/j.ymthe.2005.07.075
536. Adenoviral Vector-Mediated Gene Therapy for Adenocortical Carcinoma: Therapeutic Strategies and Safety Considerations
Luisa Barzon, Urska Trost, Monia Pacenti, Anna-Lisa Stefani, Marta Trevisan, Giulia Masi, Karina Fincati and Giorgio Pal|[ugrave]|
Mol Ther 11: S207-S208; doi:10.1016/j.ymthe.2005.07.076
537. Transcriptionally Targeting the Survivin Promoter to Human Gliomas
Zeng B. Zhu, Winan J. Houdt, Yosef S. Haviv, Baogen Lu, Minghui Wang, Angel A. Rivera, Ilya V. Ulasov, Maciej S. Lesniak, Gene P. Siegal, Clemens M.F. Dirven and David T. Curiel
Mol Ther 11: S208-S208; doi:10.1016/j.ymthe.2005.07.077
538. Fiber Chimeric Oncolytic Adenoviral Vectors Mediate Efficient Gene Transfer and Oncolysis of Head and Neck Cancer and Melanoma Cells In Vitro and In Vivo
Shanthi Ganesh, Yuanhao Li, Peter Working, P. Seshidhar Reddy and De-Chao Yu
Mol Ther 11: S208-S208; doi:10.1016/j.ymthe.2005.07.078
539. Antitumor Activity of an hTERT-Specific, GFP Expressing Oncolytic Adenovirus
John J. Davis, Li Wang, Lidong Zhang, Wei Guo, Fuminori Teraishi, Kai Xu, Lin Ji and Bingliang Fang
Mol Ther 11: S208-S209; doi:10.1016/j.ymthe.2005.07.079
540. Re-Targeting of Adenoviral Vector-Mediated Interferon-|[gamma]| Gene Transfer to Colon Cancer Cells That Express the Human Carcinoembryonic Antigen
Maaike Everts, Jing Li, Krishnakant Pondugula, Angel A. Rivera, David T. Curiel and J. Michael Mathis
Mol Ther 11: S209-S209; doi:10.1016/j.ymthe.2005.07.080
541. Oncolytic Effects of Conditionally Replicating Adenoviruses (CRAds) with Mutations in E1A and E1B Regions
Hyunhee Kim, Jaesung Kim, Kyung-Ju Choi, Pyung Hwan Kim, Tae Young Koo, Ahmed M. Al-Abd, Hye Jin Choi, Joo-Hang Kim and Chae-Ok Yun
Mol Ther 11: S209-S209; doi:10.1016/j.ymthe.2005.07.081
542. Targeting EGFR with Metabolically Biotinylated Fiber-Mosaic Adenovirus
Larisa Pereboeva, Svetlana Komarova, Selvarangan Ponnazhagan and David T. Curiel
Mol Ther 11: S209-S210; doi:10.1016/j.ymthe.2005.07.082
543. Enhanced Glia-Specific Expression Using GFAP-'Super'Promoters in an Adenoviral Context In Vitro and In Vivo
Bertie de Leeuw, Maarten ter Horst, Mark Rodijk, Rob C. Hoeben, Michael Brenner and Peter A.E. Sillevis Smitt
Mol Ther 11: S210-S210; doi:10.1016/j.ymthe.2005.07.083
544. Interferon alpha-2b Gene Delivery for Bladder Cancer Demonstrates Feasibility of Repeated Intravesical Dosing with an Adenovirus Vector
Heidrun Engler, Robert J. Connor, Jennifer M. Anderson, Drake LaFace and Daniel C. Maneval
Mol Ther 11: S210-S211; doi:10.1016/j.ymthe.2005.07.084
545. Adenovirus Mediated Gene Transfer and Oncolysis In Vitro in Head and Neck Cancer and Melanoma Cells Enhanced by Polycations
Lian Mo, Gary Lee, Shanthi Ganesh, Yuanhao Li, Peter Working, P. Seshidhar Reddy and De-Chao Yu
Mol Ther 11: S211-S211; doi:10.1016/j.ymthe.2005.07.085
546. Gene Therapy of Ovarian Cancer by IAI.3B Promoter Driven Oncolytic Adenovirus
Katsuyuki Hamada, Toshiro Shirakawa and Akinobu Gotoh
Mol Ther 11: S211-S211; doi:10.1016/j.ymthe.2005.07.086
547. Improvement of Liver Gene Transfer by First and Third Generation Adenoviral Vectors
Julien S. Crettaz, Pedro Berraondo, Itsaso Mauleon, Laura Ochoa, Veijay Shankar, Miguel Barajas, Maider Zabala, Nico van Rooijen, Stefan Kochanek, Cheng Qian, Jesus Prieto, Ruben Hernandez-Alcoceba and Gloria Gonzalez-Aseguinolaza
Mol Ther 11: S211-S211; doi:10.1016/j.ymthe.2005.07.087
548. Ethanol Increases Transgene Expression in Parenchymal Liver Cells after Adenoviral Transfer in Rabbits
Jan Snoeys, Joke Lievens, Yingmei Feng, Peter Frederik, D|[eacute]|sir|[eacute]| Collen, Eddie Wisse and Bart De Geest
Mol Ther 11: S212-S212; doi:10.1016/j.ymthe.2005.07.088
549. Peripheral Gene Delivery of Glial Cell Line-Derived Neurotrophic Factor Alleviated Neurological Deficits in Diabetic Rats
Guei-Sheung Liu, Chiou-Lian Lai, Sheng-Long Howng and Ming-Hong Tai
Mol Ther 11: S212-S212; doi:10.1016/j.ymthe.2005.07.089
550. Adenoviral-Mediated Antioxidant Overexpression: Possible Protective Role Against Hyperglycemic Conditions in Human Aortic Endothelial Cells
Aoife Duffy, Aaron Liew, Afshin Samali and Timothy O'Brien
Mol Ther 11: S212-S213; doi:10.1016/j.ymthe.2005.07.090
551. Enhanced Cell Killing Effect of E1 Modified Adenoviruses Expressing HSV-TK Suicide Gene
Yoon-A Kang, Dong Hyun Ko, Jaesung Kim Kim, Young-Sook Lee, Oh-Joon Kwon, Joo Hyuk Sohn, Chae-Ok Yun and Joo-Hang Kim
Mol Ther 11: S213-S213; doi:10.1016/j.ymthe.2005.07.091
552. Gene Therapy of Uterine Fibroids: Adenovirus-Mediated Expression of Dominant Negative Estrogen Receptor Inhibits ERE-Reporter Transactivation in Rat and Human Leiomyoma Cells.
Ayman Al-Hendy
Mol Ther 11: S213-S213; doi:10.1016/j.ymthe.2005.07.092
553. A Potent Replicative Delta Adenoviral Vector for HPV Tumors
Ivan Delgado-Enciso, Irma A. Martinez-Davila, Rocio Ortiz-Lopez, Ramon Alemany-Bonastre, Christian I. Silva-Platas, Angel Lugo-Trampe, Hugo A. Barrera-Saldana and Augusto Rojas-Martinez
Mol Ther 11: S213-S213; doi:10.1016/j.ymthe.2005.07.093
554. Evaluation of Viral Vector Gene Delivery Systems in Endothelial Cells In Vitro and Ex Vivo
Yanjuan Lin, Anming Xiong and Maria T. Millan
Mol Ther 11: S213-S214; doi:10.1016/j.ymthe.2005.07.094
555. An Oncolytic Adenovirus Controlled by a Modified Telomerase Promoter Is Attenuated in Telomerase-Negative Cells, but Shows Reduced Activity in Cancer Cells
Sergia Bortolanza, Qian Cheng, Gabriela M. Kramer, Celia Gomar Technician, Fabio Farinati, Jesus Prieto and Ruben Hernandez-Alcoceba
Mol Ther 11: S214-S214; doi:10.1016/j.ymthe.2005.07.095
556. Another Hepatic Control Region for Sustained Expression of Human Factor IX in the Mouse Liver
Ji Eun Lee, Hong Sung Kim, Keun Sik Kim, Eun Jung Kim, Jong Chul Kim, In Ho Song and Yong Serk Park
Mol Ther 11: S214-S215; doi:10.1016/j.ymthe.2005.07.096
557. Unraveling the Molecular Mechanisms Responsible for Episomal Transgene Silencing In Vivo
Zhi-Ying Chen, Cheng-Yi He, Hui Xu and Mark A. Kay
Mol Ther 11: S215-S215; doi:10.1016/j.ymthe.2005.07.097
558. cGMP Production of Plasmid DNA for Phase I Clinical Studies in an Academic Center
Mark Przybylowski, Shirley M. Bartido, Michel Sadelain and Isabelle Riviere
Mol Ther 11: S215-S215; doi:10.1016/j.ymthe.2005.07.098
559. Potentiation of DNA Vaccination Using an Integrated Application System for Electroporation-Mediated Intramuscular Delivery
Alain Luxembourg, Drew Hannaman, Steve Masterson, Barry Ellefsen, Gerald Nakamura and Robert Bernard
Mol Ther 11: S215-S216; doi:10.1016/j.ymthe.2005.07.099
560. Optimization of E. coli Fermentation for Plasmid DNA Production
Aaron Carnes, Williams James and Hodgson Clague
Mol Ther 11: S216-S216; doi:10.1016/j.ymthe.2005.07.100
561. Analytical Characterization of Supercoiled Plasmids
Anthony P. Green, Irina Tumanova, Joseph Burzynski, Dana Rosencrance, Julie Brunbeck, Jason Scheidel, S. Fernando Ausar and C. Russell Middaugh
Mol Ther 11: S216-S216; doi:10.1016/j.ymthe.2005.07.101
562. Study on the Inhibitory Effect of Antisense ETAR Oligodeoxynucleotides for the Proliferation of Vascular Smooth Cells
Lan Zhang, Baigen Zhang and Jiwei Zhang
Mol Ther 11: S217-S217; doi:10.1016/j.ymthe.2005.07.102
563. Differential Histone Modifications in Transcriptional Active Versus Silenced Episomal Vectors In Vivo
Efren Riu, Zhi-Ying Chen and Mark A. Kay
Mol Ther 11: S217-S217; doi:10.1016/j.ymthe.2005.07.103
564. Delivery of Episomal Vectors Carrying Large Genomic Regions for Gene Therapy
Wing T. Cheung, Catherine Grillot-Courvalin and Clare Huxley
Mol Ther 11: S217-S218; doi:10.1016/j.ymthe.2005.07.104
565. A Ready-to-Use Process for Large-Scale Plasmid DNA Manufacturing
Astrid Breul, Wayne Tvrdik, Markus M|[uuml]|ller and Joachim Schorr
Mol Ther 11: S218-S218; doi:10.1016/j.ymthe.2005.07.105
566. Silencing of Plasmid DNA after Hydrodynamics-Based Transfection in Mice
Hiroshi Ochiai, Hideyoshi Harashima and Hiroyuki Kamiya
Mol Ther 11: S218-S218; doi:10.1016/j.ymthe.2005.07.106
567. Prevention of Bilirubin Toxicity in the Gunn Rat by Long-Term Correction of Hyperbilirubinemia with Liver-Specific Plasmid-Based Gene Transfer
Istvan Danko and Zhen Jia
Mol Ther 11: S218-S219; doi:10.1016/j.ymthe.2005.07.107
568. In Vitro SFHR-Mediated Modification of SMA Locus in Different Human Trophoblast Cells
Federica Sangiuolo, Antonio Filareto, Paola Spitalieri, Lucia Scaldaferri, Emanuela Bruscia, Ruggiero Mango, Citro Gennaro, Massimo De Felici and Giuseppe Novelli
Mol Ther 11: S219-S219; doi:10.1016/j.ymthe.2005.07.108
569. Therapeutic Ultrasound for Anti-Angiogenic Gene Delivery: Mechanism Studies and Application for Prostate Tumor
Maayan Duvshani-Eshet and Marcelle Machluf
Mol Ther 11: S219-S220; doi:10.1016/j.ymthe.2005.07.109
570. The Effects of Cyclic Stretch on the Cytoskeleton and Its Role in Gene Transfer to the Alveolar Epithelium
R. Christopher Geiger and David A. Dean
Mol Ther 11: S220-S220; doi:10.1016/j.ymthe.2005.07.110
571. Development of a Quantitative Potency Assay for Quality Control Testing for pVGI.1(VEGF2), a Naked DNA Vector
Li-chun Huang, Qing Wang, Jiemin Zhou, Hsing-yi Jan and Yawen L. Chiang
Mol Ther 11: S220-S220; doi:10.1016/j.ymthe.2005.07.111
572. Alveolar Epithelial Cell-Specific Plasmid Nuclear Import
James V. DeGiulio and David A. Dean
Mol Ther 11: S221-S221; doi:10.1016/j.ymthe.2005.07.112
573. Investigation into the Frequency of Post-Integrative Gene Silencing Using a Non-Selective Sleeping Beauty Transposition System
Brian S. Garrison, Stephen R. Yant, Jacob G. Mikkelsen and Mark A. Kay
Mol Ther 11: S221-S221; doi:10.1016/j.ymthe.2005.07.113
574. Early Stage Product Development to Scale-Up: Use of Mini-Fermentation System for Screening and Process Development of Plasmid DNA Products
Sriram Ramakrishnan, Justin Miller, Jeffrey Darnell and Henry Hebel
Mol Ther 11: S221-S222; doi:10.1016/j.ymthe.2005.07.114
575. In Vivo Evaluation of Supercoiled Plasmids
Anthony P. Green, Irina Tumanova, Joseph Burzynski, Dana Rosencrance, Julie White, Jason Scheidel, David Weiner and Jean Boyer
Mol Ther 11: S222-S222; doi:10.1016/j.ymthe.2005.07.115
576. Hydrophobic Portion of Cationic Amphiphiles Are More Important Than We Think for Transfection Efficiency
Li Wang, Yaeko Hiyama, Harsh Parikh and Robert C. MacDonald
Mol Ther 11: S222-S222; doi:10.1016/j.ymthe.2005.07.116
577. Distribution, Time Course, In-Vivo Imaging, Expression and Inflammatory Response after Non-Viral Gene Delivery to Rat and Primate CNS
James G. Hecker, Ellen S. Hauck, Michael H. Nantz and Alice F. Tarantal
Mol Ther 11: S223-S223; doi:10.1016/j.ymthe.2005.07.117
578. Quantitative Evaluation of the Relationship between Efficiency of Nuclear Transfer of Plasmid DNA and Trans-Gene Expression in Individual Cell: Consideration of Mechanism Underlying in the Heterogeneity of the Trans-Gene Expression Via Artificial Vector
Hidetaka Akita, Rie Ito, Hiroyuki Kamiya, Kentaro Kogure and Hideyoshi Harashima
Mol Ther 11: S223-S223; doi:10.1016/j.ymthe.2005.07.118
579. In-Vivo Time Course of Reporter Gene Expression after Nucleic Acid Delivery to the Lateral Ventricle in Rat Brain
Ellen S. Hauck, Shaomin Zou, Michael H. Nantz and James G. Hecker
Mol Ther 11: S224-S224; doi:10.1016/j.ymthe.2005.07.119
580. Vitreous - A Barrier to Non-Viral Ocular Gene Therapy
Liesbeth Peeters, Niek N. Sanders, Kevin Braeckmans, Stefaan C. DeSmedt and Joseph Demeester
Mol Ther 11: S224-S224; doi:10.1016/j.ymthe.2005.07.120
581. Development of a Non-Viral DNA Vector Multifunctional Envelop-type Nano Device Modified with Octaarginine Peptide
Kentaro Kogure, Ikramy A. Khalil, Rumiko Moriguchi, Shiroh Futaki and Hideyoshi Harashima
Mol Ther 11: S224-S225; doi:10.1016/j.ymthe.2005.07.121
582. Synthetic siRNA Can Activate the Mammalian Innate Immune Response in a Sequence Dependent Manner
Adam D. Judge, Janet R. Shaw, Vandana Sood, Kevin McClintock and Ian MacLachlan
Mol Ther 11: S225-S225; doi:10.1016/j.ymthe.2005.07.122
583. The Transgene Expression in the Lung after Systemic Injection of DNA Formulated into Nanoparticles with Linear PEI Depends of Bolus Effect and the Presence of Free PEI
Jean Luc Coll, Olivier Freund, Alain Cuzange, Jean Serge Remy, Jean Paul Behr and Patrick Erbacher
Mol Ther 11: S225-S225; doi:10.1016/j.ymthe.2005.07.123
584. Gene Delivery to Primary Neuronal Cells
Shaomin Zou, Ellen S. Hauck, Michael H. Nantz and James G. Hecker
Mol Ther 11: S225-S226; doi:10.1016/j.ymthe.2005.07.124
585. A Water-Soluble Lipoploymer Gene Carrier to Deliver a Bicistronic Plasmid Conveying IL-2 and Soluble Flk-1 for the Treatment of Renal Cell Carcinoma Tumors
James W. Yockman, Won Jong Kim and Sung Wan Kim
Mol Ther 11: S226-S226; doi:10.1016/j.ymthe.2005.07.125
586. Novel Lipidic Vectors for Targeted Delivery of Functional Oligonucleotides to Pulmonary Endothelium
Annette S. Wilson, Stephen J. Kennel, Leaf Huang, Bruce R. Pitt and Song Li
Mol Ther 11: S226-S226; doi:10.1016/j.ymthe.2005.07.126
587. Artificial Viral-Like Gene Delivery System Multifunctional Envelope-type Nano Device Equipped with Transferrin and a pH-Sensitive Fusogenic Peptide
Shinji Chaki, Kentaro Sasaki, Kentaro Kogure, Hirofumi Hamada, Masaharu Ueno, Shiroh Futaki and Hideyoshi Harashima
Mol Ther 11: S227-S227; doi:10.1016/j.ymthe.2005.07.127
588. Structure-Activity Relationships in Two Series of Pyridinium Gemini Surfactants for Gene Delivery
Marc A. Ilies, Betty H. Johnson, William A. Seitz, Ed L. Ezell, Aaron Miller, E. Brad Thompson and Alexandru T. Balaban
Mol Ther 11: S227-S227; doi:10.1016/j.ymthe.2005.07.128
589. Construction and Antiproliferative Effect of mc-|[gamma]|IFNs
Jiangxue Wu, Bijun Huang, Benling Xu and Gang Xue
Mol Ther 11: S227-S228; doi:10.1016/j.ymthe.2005.07.129
590. Efficient, Serum-Resistant Transfection of Murine Squamous Cell Carcinoma Cells by Metafectene and GeneJammer: Application to HSV-tk/Ganciclovir Gene Therapy
Krystyna Konopka, Nathan Overlid and Nejat D|[uuml]|zg|[uuml]|nes
Mol Ther 11: S228-S228; doi:10.1016/j.ymthe.2005.07.130
591. Transfection Efficiency of Monomolecular DNA Nanoparticles Formulated with New Perfluorinated Polycationic Dimerizable Detergents
Karine Fabio, Christophe Di Giorgio and Pierre Vierling
Mol Ther 11: S228-S229; doi:10.1016/j.ymthe.2005.07.131
592. A Multifunctional Envelope-Type Nano Device for the Novel Gene Delivery of siRNA Plasmids: Optimization of Condensing Polycations
Rumiko Moriguchi, Kentaro Kogure, Hidetaka Akita, Siroh Futaki, Makoto Miyagishi, Kazunari Taira and Hideyoshi Harashima
Mol Ther 11: S229-S229; doi:10.1016/j.ymthe.2005.07.132
593. Progress towards DNA-Based and siRNA Therapeutics
Michael R. Jorgensen, Michael Keller, Eric Perouzel and Andrew D. Miller
Mol Ther 11: S229-S230; doi:10.1016/j.ymthe.2005.07.133
594. Enhancement of Cellular and Nuclear Uptake of Macromolecules, Therapeutic Genes and Lipoplexes by Using NLS and PTD Containing Viral Peptides
Roosmarijn Vandenbroucke, Niek N. Sanders, Stefaan De Smedt and Joseph Demeester
Mol Ther 11: S230-S230; doi:10.1016/j.ymthe.2005.07.134
595. Synthesis of Novel Polyhydroxylalkyleneamine for Nonviral Gene Deliver
Li Qun, Guisheng Zhang and Dexi Li
Mol Ther 11: S230-S230; doi:10.1016/j.ymthe.2005.07.135
596. Incorporation of a Hepatocyte-Specific Compound in Polycationic Liposomes Enhances Gene Transfection in Hep G2 Cells
Michelle R. McCombs, Gideon O. Berger, Michael H. Nantz and Jian Wu
Mol Ther 11: S230-S231; doi:10.1016/j.ymthe.2005.07.136
597. Liver Tissue Engineering at Extra-Hepatic Site: A Novel Therapeutic Approach toward Hemophilia
Kazuo Ohashi, Mark A. Kay, Takashi Yokoyama, Hiroyuki Kuge, Hiromichi Kanehiro, Michiyoshi Hisanaga, Saiho Ko, Hiroyuki Naka, Akira Yoshioka and Yoshiyuki Nakajima
Mol Ther 11: S231-S231; doi:10.1016/j.ymthe.2005.07.137
598. In-Vivo Test of Coagulation Factor VIII with Improved Properties for Hemophilia A Gene Therapy by Helper-Dependent Adenoviral Vectors
Vincenzo Cerullo, Michael McCormack, Racel Garcia, Christian Clarke, Steven W. Pipe and Brendan Lee
Mol Ther 11: S231-S231; doi:10.1016/j.ymthe.2005.07.138
599. Development of EIAV-Based Vectors for the Treatment of Haemophilia A
Emily J. Custard, Fraser J. Wilkes, Susan M. Kingsman, Kyriacos A. Mitrophanous and Pippa A. Radcliffe
Mol Ther 11: S231-S232; doi:10.1016/j.ymthe.2005.07.139
600. A Novel Gene-Deleted Adenoviral Vector for Somatic Integration and Long-Term Phenotypic Correction of Murine and Canine Hemophilia B
Anja Ehrhardt, Hui Xu, Stephen R. Yant, Jeffrey A. Engler and Mark A. Kay
Mol Ther 11: S232-S232; doi:10.1016/j.ymthe.2005.07.140
601. Persistent Expression of Factor VIII In Vivo Following FIV Lentiviral Gene Transfer
Yubin Kang, Litao Xie, Diane Thi Tran, Colleen S. Stein, Melissa Hickey, Beverly L. Davidson and Paul B. McCray
Mol Ther 11: S232-S232; doi:10.1016/j.ymthe.2005.07.141
602. Induction of Tolerance to Human Factor VIII after Neonatal Gene Transfer of a Retroviral Vector Is Dose-Dependent in Mice and Is Not Effective in Cats
Lingfei Xu, Manxue Mei, Mark E. Haskins, Karyn Cullen and Katherine P. Ponder
Mol Ther 11: S233-S233; doi:10.1016/j.ymthe.2005.07.142
603. Correction of Hemophilia B Phenotype by Novel Method of Regional Intravenous Delivery of AAV Vector to Skeletal Muscle of Hemophilia B Dogs
Valder Arruda, Hansell Stedman, Haiyan Jian, Glenn Pierce, Joerg Schuettrumpf, Christian Furlan Freguia, Stefano Baila, Kapil Gopal, Timothy Nichols and Katherine High
Mol Ther 11: S233-S233; doi:10.1016/j.ymthe.2005.07.143
604. Long-Term, Erythroid-Specific Expression of Human Factor IX in Hemophilic Mice Engrafted with Lentiviral Vector-Transduced Hematopoietic Stem Cells
Alex H. Chang, Matthias Stephan and Michel Sadelain
Mol Ther 11: S234-S234; doi:10.1016/j.ymthe.2005.07.144
605. Efficient AAV 1 and AAV2 Hybrid Vector for Gene Therapy of Hemophilia
Bernd Hauck, Ruian Xu, Jing Xie, Qiulan Ding, Wenman Wu, Matthew Sipler, Hongli Wang, Katherine High and Weidong Xiao
Mol Ther 11: S234-S234; doi:10.1016/j.ymthe.2005.07.145
606. Molecular Characterization of Hereditary Factor VII Deficiency in Beagles
Majed N. Aljamali, Mary Beth Callan, Eleanor S. Pollak, Urs Giger, Petra Werner, Monika Griot-Wenk and Katherine A. High
Mol Ther 11: S234-S235; doi:10.1016/j.ymthe.2005.07.146
607. Long-Term Phenotypic Correction of Canine Hemophilia B Following Systemic Administration of Helper Dependent Adenoviral Vector
Nicola Brunetti-Pierri, Timothy Nichols, Donna Palmer, Stephanie McCorquodale, Elizabeth Merricks, Arthur Beaudet and Philip Ng
Mol Ther 11: S235-S235; doi:10.1016/j.ymthe.2005.07.147
608. Cytotoxic T Lymphocyte Response to AAV2- and AAV8-Mediated Human Factor IX Gene Therapy in Mice
Jian Chen, Hui-Chen Hsu, Alex Schlachterman, Katherine A. High and John D. Mountz
Mol Ther 11: S235-S236; doi:10.1016/j.ymthe.2005.07.148
609. Long Term Persistence of Canine Factor IX-Specific Th1 Lymphocytes in Regional Lymph Nodes after AAV1-Mediated Intramuscular Gene Transfer in a Hemophilia B Dog
Federico Mingozzi, Denise Sabatino, Timothy Nichols, Stephanie McCroquodale, Valder Arruda and Katherine High
Mol Ther 11: S236-S236; doi:10.1016/j.ymthe.2005.07.149
610. Evaluation of Three Reticuloendothelial System Blocking Modalities on the Outcome of Adenoviral Mediated Gene Therapy in Hemophilic Mice
Maha Othman, Andrea Labelle, Christine Hough, Alan H. Lazarus and David Lillicrap
Mol Ther 11: S236-S236; doi:10.1016/j.ymthe.2005.07.150
611. Nonviral Gene Transfer of Factor VII as Alternative Treatment for Hemophilia A
Steven C. Chen, Daniel Greenberg, Peiqing Ye, Earl W. Davie and Carol H. Miao
Mol Ther 11: S237-S237; doi:10.1016/j.ymthe.2005.07.151
612. Determination of Specific Th1 and Th2 CD4 T Cell Responses in AAV2- and AAV8-Mediated Human Factor IX Gene Therapy in Mice
Jian Chen, Hui-Chen Hsu, Alex Schlachterman, Katherine A. High and John D. Mountz
Mol Ther 11: S237-S237; doi:10.1016/j.ymthe.2005.07.152
613. Dependence of Vector Dose and Age of Mice in the Induction of Immune Response Against Factor VIII Following Liver-Directed Nonviral Gene Transfer
Peiqing Ye and Carol H. Miao
Mol Ther 11: S238-S238; doi:10.1016/j.ymthe.2005.07.153
614. Frequency of T Cell Responses to AAV-2 Capsid in Peripheral Blood Mononuclear Cells of Normal Subjects Does Not Correlate with Anti-AAV2 Antibody Titers
Denise Sabatino, Federico Mingozzi, Yi-lin Liu, Daniel Hui, Michael Tigges, Glenn Pierce and Katherine High
Mol Ther 11: S238-S238; doi:10.1016/j.ymthe.2005.07.154
615. A Self-Limiting but Prolonged Inflammatory Response to AAV-Factor IX Gene Transfer to Skeletal Muscle
L. Wang and R.W. Herzog
Mol Ther 11: S238-S239; doi:10.1016/j.ymthe.2005.07.155
616. Protection of Monocrotaline-Induced Pulmonary Hypertension by Adeno-Associated Virus Vector-Mediated Interleukin-10 Expression
Takayuki Ito, Takashi Okada, Hiroshi Miyashita, Tatsuya Nomoto, Yoshikazu Maeda, Mutsuko Sarukawa, Masahisa Shimpo, Toru Yoshioka, Takashi Matsushita, Hiroaki Mizukami, Akihiro Kume, Keiji Yamamoto, Uichi Ikeda, Kazuyuki Shimada and Keiya Ozawa
Mol Ther 11: S239-S239; doi:10.1016/j.ymthe.2005.07.156
617. A Synthetic Promoter Drives Macrophage Expression of ApoE and Ameliorates Atherosclerosis
Senlin Li, Weijing He, Mei Qiang, Robert A. Reddick and Gregory L. Freeman
Mol Ther 11: S239-S240; doi:10.1016/j.ymthe.2005.07.157
618. A Novel Gene Therapy Strategy for Vascular Ehlers-Danlos Syndrome by the Combination with RNAi Mediated Inhibition of a Mutant Allele and Transcriptional Activation of a Normal Allele
Atsushi Watanabe, Takahito Wada, Kumiko Tei, Ryuichiro Hata, Yoshimitsu Fukushima and Takashi Shimada
Mol Ther 11: S240-S240; doi:10.1016/j.ymthe.2005.07.158
619. Co-Expression of AAV Mediated Angiopoietin-1 and VEGF in Ischemic Hearts Yield Leakage-Resistant Blood Vessels and Better Therapeutic Effect Than VEGF Alone
Hua Su, Shuji Joho, Yu Huang, Alicia Barcena, Janice Arakawa-Hoyt, William Grossman and Yuet W. Kan
Mol Ther 11: S240-S240; doi:10.1016/j.ymthe.2005.07.159
620. SMC-Specific Transcription Elements for Improved Adenoviral-Mediated Transgene Expression in Saphenous Veins
Angelika B. Kritz, Song Wan, Anthony P. C. Yim, Paul A. Kingston and Andrew H. Baker
Mol Ther 11: S240-S241; doi:10.1016/j.ymthe.2005.07.160
621. Angiogenesis and Arteriogenesis in Ischemic Skeletal Muscles Following VEGF Gene Transfer by Adeno-Associated Virus Serotype 1 Vectors
Hua Yan, Xiaobing Wu, Lingyun Zu, Yanhong Guo, Peng Zhang and Wei Gao
Mol Ther 11: S241-S241; doi:10.1016/j.ymthe.2005.07.161
622. PhiC31 Integrase as a Tool: Gene Therapy for Angiogenesis
Joylette L. Portlock, Sohail Jarrahian, Carmen Bertoni, Thomas A. Rando and Michele P. Calos
Mol Ther 11: S242-S242; doi:10.1016/j.ymthe.2005.07.162
623. Receptor-Independent Cell Entry of Adenovirus-Polylactide Nanoparticle Composites Leads to an Increased Gene Expression in Endothelial and Smooth Muscle Cells
Michael Chorny, Ilia Fishbein, Ivan Alferiev, Origene Nyanguile and Robert J. Levy
Mol Ther 11: S242-S242; doi:10.1016/j.ymthe.2005.07.163
624. Development of a Novel Ribbon-type NF-|[kappa]|B Decoy Oligodeoxynucleotides to Treat Cardiovascular Diseases
Mariana K. Osako, Naruya Tomita, Yasuo Kunugiza, Keishi Sekiguchi, Keiko Izawa and Ryuichi Morishita
Mol Ther 11: S242-S243; doi:10.1016/j.ymthe.2005.07.164
625. Adenoviral-Mediated Gene Delivery of a Constitutively Active Form of Early Growth Response Factor-1 Increases Tissue Perfusion in a Murine Model of Hindlimb Ischemia
Jonghoe Byun, Young-Sam Lee, Hyung-Suk Jang, Jeong-Min Kim, Jung-Sun Lee, Jae-Young Lee, Koung Li Kim, In-Soon Shin, Wonhee Suh, Jin-Ho Choi, Eun-Seok Jeon and Duk-Kyung Kim
Mol Ther 11: S243-S243; doi:10.1016/j.ymthe.2005.07.165
626. Ultrasound-Triggered/Enhanced Delivery of Oligonucleotides into Aorta
Shao-LIng Huang, David D. McPherson and Robert C. MacDonald
Mol Ther 11: S243-S243; doi:10.1016/j.ymthe.2005.07.166
627. Adenoviral-Mediated Systemic Transduction of the Angiotensin II (Ang II) Type 2 Receptor (AT2R) Enhances the Hypotensive Action of Losartan
Hongwei Li, Yongxin Gao, Justin Grobe, Mohan Raizada, Michael Katovich and Colin Sumners
Mol Ther 11: S244-S244; doi:10.1016/j.ymthe.2005.07.167
628. Adenovirus-Mediated Expression of |[beta]|-Adrenergic Receptor Kinase C-Terminus Reduces Intimal Hyperplasia and Luminal Stenosis in a Pig Model of Arteriovenous Polytetrafluoroethylene Graft Failure
Zhengyu Luo, Geoffrey Y. Akita, Taro Date, Chris Treleaven, Karen A. Vincent, Denise Woodcock, Seng H. Cheng, Richard J. Grogery and Canwen Jiang
Mol Ther 11: S244-S244; doi:10.1016/j.ymthe.2005.07.168
Abstract |