TABLE OF CONTENTS

Volume 10, Issue 6 (December 2004)

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Editorial

Thanks, Adieu and Farewell

Inder M Verma

Mol Ther 10: 973; doi:10.1016/j.ymthe.2004.11.003

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Inside this Month

Inside this Month

Mol Ther 10: 974; doi:10.1016/j.ymthe.2004.11.004

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Research Update

Research Update

Mol Ther 10: 975; doi:10.1016/j.ymthe.2004.10.012

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Meeting Report

Workshop on Long-term Follow-up of Participants in Human Gene Transfer Research

Kara Nyberg, Barrie J. Carter, Theresa Chen, Cynthia Dunbar, Terrence R. Flotte, Stephen Rose, Daniel Rosenblum, Stephanie L. Simek and Carolyn Wilson

Mol Ther 10: 976-980; doi:10.1016/j.ymthe.2004.10.011

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History

Adeno-associated Virus and the Development of Adeno-associated Virus Vectors: A Historical Perspective

Barrie J. Carter

Mol Ther 10: 981-989; doi:10.1016/j.ymthe.2004.09.011

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Original Articles

Dual Therapeutic Utility of Proteasome Modulating Agents for Pharmaco-gene Therapy of the Cystic Fibrosis Airway

Liang N. Zhang, Phil Karp, Christopher J. Gerard, Eric Pastor, Douglas Laux, Keith Munson, Ziying Yan, Xiaoming Liu, Simon Godwin, Christie P. Thomas, Joseph Zabner, Huidong Shi, Charles W. Caldwell, Richard Peluso, Barrie Carter and John F. Engelhardt

Mol Ther 10: 990-1002; doi:10.1016/j.ymthe.2004.08.009

Intrapleural Administration of a Serotype 5 Adeno-associated Virus Coding for alpha1-Antitrypsin Mediates Persistent, High Lung and Serum Levels of alpha1-Antitrypsin

Bishnu De, Adriana Heguy, Philip L. Leopold, Nabil Wasif, Robert J. Korst, Neil R. Hackett and Ronald G. Crystal

Mol Ther 10: 1003-1010; doi:10.1016/j.ymthe.2004.08.022

Cellular Uptake of Arginine-Rich Peptides: Roles for Macropinocytosis and Actin Rearrangement

Ikuhiko Nakase, Miki Niwa, Toshihide Takeuchi, Kazuhiro Sonomura, Noriko Kawabata, Yukihiro Koike, Masanori Takehashi, Seigo Tanaka, Kunihiro Ueda, Jeremy C. Simpson, Arwyn T. Jones, Yukio Sugiura and Shiroh Futaki

Mol Ther 10: 1011-1022; doi:10.1016/j.ymthe.2004.08.010

A Human Single-Chain Fv Intrabody Blocks Aberrant Cellular Effects of Overexpressed alpha-Synuclein

Chun Zhou, Sharareh Emadi, Michael R. Sierks and Anne Messer

Mol Ther 10: 1023-1031; doi:10.1016/j.ymthe.2004.08.019

Characterization of Intraperitoneal, Orthotopic, and Metastatic Xenograft Models of Human Ovarian Cancer

Tanya J. Shaw, Mary K. Senterman, Kerri Dawson, Colleen A. Crane and Barbara C. Vanderhyden

Mol Ther 10: 1032-1042; doi:10.1016/j.ymthe.2004.08.013

Prolonged Survival of Mice with Multiple Liver Metastases of Human Colon Cancer by Intravenous Administration of Replicable E1B-55K-Deleted Adenovirus with E1A Expressed by CEA Promoter

Tamotsu Sagawa, Minoru Takahashi, Tsutomu Sato, Yasushi Sato, Yue Lu, Tetsuya Sumiyoshi, Yasuyuki Yamada, Satoshi Iyama, Junki Fukaura, Katsunori Sasaki, Hirofumi Hamada, Koji Miyanishi, Tetsuji Takayama, Junji Kato and Yoshiro Niitsu

Mol Ther 10: 1043-1050; doi:10.1016/j.ymthe.2004.08.023

Targeting Prostate Cancer with Conditionally Replicative Adenovirus Using PSMA Enhancer

Sang-Jin Lee, Yanping Zhang, Sang Don Lee, Chaeyong Jung, Xiong Li, Hong-Sup Kim, Kyung-Hee Bae, Meei-Huey Jeng, Chinghai Kao and Thomas Gardner

Mol Ther 10: 1051-1058; doi:10.1016/j.ymthe.2004.08.028

Adenovirus-Mediated FLT1-Targeted Proapoptotic Gene Therapy of Human Prostate Cancer

Sergey A. Kaliberov, Lyudmila N. Kaliberova, Cecil R. Stockard, William E. Grizzle and Donald J. Buchsbaum

Mol Ther 10: 1059-1070; doi:10.1016/j.ymthe.2004.08.024

Inflammatory and Anti-glioma Effects of an Adenovirus Expressing Human Soluble Fms-like Tyrosine Kinase 3 Ligand (hsFlt3L): Treatment with hsFlt3L Inhibits Intracranial Glioma Progression

Sumia Ali, James F. Curtin, Jeffrey M. Zirger, Weidong Xiong, Gwendalyn D. King, Carlos Barcia, Chunyan Liu, Mariana Puntel, Shyam Goverdhana, Pedro R. Lowenstein and Maria G. Castro

Mol Ther 10: 1071-1084; doi:10.1016/j.ymthe.2004.08.025

Bystander Activity of Ad-mda7: Human MDA-7 Protein Kills Melanoma Cells via an IL-20 Receptor-Dependent but STAT3-Independent Mechanism

Sunil Chada, Abner M. Mhashilkar, Rajagopal Ramesh, John B. Mumm, R. Bryan Sutton, Dora Bocangel, Mingzhong Zheng, Elizabeth A. Grimm and Suhendan Ekmekcioglu

Mol Ther 10: 1085-1095; doi:10.1016/j.ymthe.2004.08.020

IL-3 or IL-7 Increases ex Vivo Gene Transfer Efficiency in ADA-SCID BM CD34+ Cells while Maintaining in Vivo Lymphoid Potential

Francesca Ficara, Daniela B. Superchi, Raisa Jofra Hernández, Cristina Mocchetti, Nicole Carballido-Perrig, Grazia Andolfi, Sara Deola, Augusto Colombo, Claudio Bordignon, José M. Carballido, Maria Grazia Roncarolo and Alessandro Aiuti

Mol Ther 10: 1096-1108; doi:10.1016/j.ymthe.2004.08.014

Retroviral Transduction of Hematopoietic Cells Differentiated from Human Embryonic Stem Cell-Derived CD45negPFV Hemogenic Precursors

Pablo Menendez, Lisheng Wang, Kristin Chadwick, Li Li and Mickie Bhatia

Mol Ther 10: 1109-1120; doi:10.1016/j.ymthe.2004.08.016

Axonal Transport of Recombinant Baculovirus Vectors

Ying Li, Xu Wang, Haiyan Guo and Shu Wang

Mol Ther 10: 1121-1129; doi:10.1016/j.ymthe.2004.08.018

Metallothionein Gene Therapy for Chemical-Induced Liver Fibrosis in Mice

Youchun Jiang and Y. James Kang

Mol Ther 10: 1130-1139; doi:10.1016/j.ymthe.2004.08.011

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Short Communication

Recombinant Adenovirus Vectors Activate the Alternative Complement Pathway, Leading to the Binding of Human Complement Protein C3 Independent of Anti-Ad Antibodies

H. Jiang, Z. Wang, D. Serra, M. M. Frank and A. Amalfitano

Mol Ther 10: 1140-1142; doi:10.1016/j.ymthe.2004.08.015

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