TABLE OF CONTENTS
Volume 10, Issue 5 (November 2004)
Editorial
Top of pageInside This Month
Top of pageResearch Update
Top of pageOriginal Articles
AAV Vector-Mediated Microdystrophin Expression in a Relatively Small Percentage of mdx Myofibers Improved the mdx Phenotype
Madoka Yoshimura, Miki Sakamoto, Madoka Ikemoto, Yasushi Mochizuki, Katsutoshi Yuasa, Yuko Miyagoe-Suzuki and Shin'ichi Takeda
Mol Ther 10: 821-828; doi:10.1016/j.ymthe.2004.07.025
Targeted Expression of Insulin-Like Growth Factor-I Reduces Early Myofiber Necrosis in Dystrophic mdx Mice
Thea Shavlakadze, Jason White, Joseph F. Y. Hoh, Nadia Rosenthal and Miranda D. Grounds
Mol Ther 10: 829-843; doi:10.1016/j.ymthe.2004.07.026
Vascular Endothelial Growth Factor Stimulates Skeletal Muscle Regeneration In Vivo
Nikola Arsic, Serena Zacchigna, Lorena Zentilin, Genaro Ramirez-Correa, Lucia Pattarini, Alessandro Salvi, Gianfranco Sinagra and Mauro Giacca
Mol Ther 10: 844-854; doi:10.1016/j.ymthe.2004.08.007
Systemic but Not Intraocular Epo Gene Transfer Protects the Retina from Light-and Genetic-Induced Degeneration
Tonia S. Rex, Mariacarmela Allocca, Luciano Domenici, Enrico M. Surace, Albert M. Maguire, Arkady Lyubarsky, Alessandro Cellerino, Jean Bennett and Alberto Auricchio
Mol Ther 10: 855-861; doi:10.1016/j.ymthe.2004.07.027
Enhanced in Vivo Selection of Bone Marrow Cells by Retroviral-Mediated Coexpression of Mutant O 6-methylguanine-DNA-methyltransferase and HOXB4
Michael D. Milsom, Lorna B. Woolford, Geoffrey P. Margison, R. Keith Humphries and Leslie J. Fairbairn
Mol Ther 10: 862-873; doi:10.1016/j.ymthe.2004.07.019
Insertion of Retroviral Vectors in NOD/SCID Repopulating Human Peripheral Blood Progenitor Cells Occurs Preferentially in the Vicinity of Transcription Start Regions and in Introns
Stephanie Laufs, K. Zsuzsanna Nagy, Frank A. Giordano, Agnes Hotz-Wagenblatt, W. Jens Zeller and Stefan Fruehauf
Mol Ther 10: 874-881; doi:10.1016/j.ymthe.2004.08.001
Competitive Repopulation Assay of Two Gene-Marked Cord Blood Units in NOD/SCID/
cnull Mice
Takashi Yahata, Kiyoshi Ando, Hiroko Miyatake, Tomoko Uno, Tadayuki Sato, Mamoru Ito, Shunichi Kato and Tomomitsu Hotta
Mol Ther 10: 882-891; doi:10.1016/j.ymthe.2004.07.029
Sustained Phenotypic Correction of Hemophilia A Mice Following Oncoretroviral-Mediated Expression of a Bioengineered Human Factor VIII Gene in Long-Term Hematopoietic Repopulating Cells
Morvarid Moayeri, Ali Ramezani, Richard A. Morgan, Teresa S. Hawley and Robert G. Hawley
Mol Ther 10: 892-902; doi:10.1016/j.ymthe.2004.08.006
Lentiviral Vector-Mediated Gene Transfer in T Cells from Wiskott–Aldrich Syndrome Patients Leads to Functional Correction
Loïc Dupré, Sara Trifari, Antonia Follenzi, Francesco Marangoni, Teresa Lain de Lera, Antonio Bernad, Silvana Martino, Shigeru Tsuchiya, Claudio Bordignon, Luigi Naldini, Alessandro Aiuti and Maria-Grazia Roncarolo
Mol Ther 10: 903-915; doi:10.1016/j.ymthe.2004.08.008
The Use of 19F Spectroscopy and Diffusion-Weighted MRI to Evaluate Differences in Gene-Dependent Enzyme Prodrug Therapies
Daniel A. Hamstra, Kuei C. Lee, Joseph M. Tychewicz, Victor D. Schepkin, Bradford A. Moffat, Mark Chen, Kenneth J. Dornfeld, Theodore S. Lawrence, Thomas L. Chenevert, Brian D. Ross, Juri T. Gelovani and Alnawaz Rehemtulla
Mol Ther 10: 916-928; doi:10.1016/j.ymthe.2004.07.022
Combination Electro-gene Therapy Using Herpes Virus Thymidine Kinase and Interleukin-12 Expression Plasmids is Highly Efficient Against Murine Carcinomas in Vivo
Tomoaki Goto, Toru Nishi, Osamu Kobayashi, Takahiko Tamura, Sukhendu B. Dev, Hideo Takeshima, Masato Kochi, Jun-ichi Kuratsu, Tsuneaki Sakata and Yukitaka Ushio
Mol Ther 10: 929-937; doi:10.1016/j.ymthe.2004.07.028
Oncolytic Effects of Adenovirus Mutant Capable of Replicating in Hypoxic and Normoxic Regions of Solid Tumor
Won-Kyung Cho, Young Rim Seong, Yeune Hee Lee, Min Ji Kim, Kyung-Sun Hwang, Jinsang Yoo, Seeyoung Choi, Cho-Rok Jung and Dong-Soo Im
Mol Ther 10: 938-949; doi:10.1016/j.ymthe.2004.07.023
Method
Self-complementary Adeno-associated Virus 2 (AAV)–T Cell Protein Tyrosine Phosphatase Vectors as Helper Viruses to Improve Transduction Efficiency of Conventional Single-Stranded AAV Vectors in Vitro and in Vivo
Li Zhong, Linyuan Chen, Yanjun Li, Keyun Qing, Kirsten A. Weigel-Kelley, Rebecca J. Chan, Mervin C. Yoder and Arun Srivastava
Mol Ther 10: 950-957; doi:10.1016/j.ymthe.2004.07.018
Trial Articles
A Phase I Open-Label, Dose-Escalation, Multi-Institutional Trial of Injection with an E1B-Attenuated Adenovirus, ONYX-015, into the Peritumoral Region of Recurrent Malignant Gliomas, in the Adjuvant Setting
E. Antonio Chiocca, Khalid M. Abbed, Stephen Tatter, David N. Louis, Fred H. Hochberg, Fred Barker, Jean Kracher, Stuart A. Grossman, Joy D. Fisher, Kathryn Carson, Mark Rosenblum, Tom Mikkelsen, Jeff Olson, James Markert, Steven Rosenfeld, L. Burt Nabors, Steven Brem, Surasak Phuphanich, Scott Freeman, Rick Kaplan and James Zwiebel
Mol Ther 10: 958-966; doi:10.1016/j.ymthe.2004.07.021
AdvHSV-tk Gene Therapy with Intravenous Ganciclovir Improves Survival in Human Malignant Glioma: A Randomised, Controlled Study
Arto Immonen, Matti Vapalahti, Kristiina Tyynelä, Heleena Hurskainen, Anu Sandmair, Ritva Vanninen, Gillian Langford, Neil Murray and Seppo Ylä-Herttuala
Mol Ther 10: 967-972; doi:10.1016/j.ymthe.2004.08.002
