TABLE OF CONTENTS
Volume 1, Issue 3 (March 2000)
Editorial
Reports of Adenovector "Death" Are Greatly Exaggerated
Malcolm Brenner
Mol Ther 1: 205; doi:10.1006/mthe.2000.0047
Commentaries
Gene Therapy for Hemophilia: A Step Closer to Reality
Gilbert C. White II and Harold R. Roberts
Mol Ther 1: 207-208; doi:10.1006/mthe.2000.0048
Gene Therapy as Drug Development
Barrie J. Carter
Mol Ther 1: 211-212; doi:10.1006/mthe.2000.0040
Review
Progress and Potential for Gene-Based Medicines
Mark R. Dyer and Paul L. Herrling
Mol Ther 1: 213-224; doi:10.1006/mthe.2000.0044
Original Articles
Role of Vector in Activation of T Cell Subsets in Immune Responses against the Secreted Transgene Product Factor IX
Paul A. Fields, Dariusz W. Kowalczyk, Valder R. Arruda, Elina Armstrong, Mark L. McCleland, J. Nathan Hagstrom, K. John Pasi, Hildegund C. J. Ertl, Roland W. Herzog and Katherine A. High
Mol Ther 1: 225-235; doi:10.1006/mthe.2000.0032
Targeted Delivery of Plasmid DNA to Myogenic Cells via Transferrin-Conjugated Peptide Nucleic Acid
Kenneth W. Liang, Eric P. Hoffman and Leaf Huang
Mol Ther 1: 236-243; doi:10.1006/mthe.2000.0043
Characterization of Anti-CCR5 Ribozyme-Transduced CD34+ Hematopoietic Progenitor Cells in Vitro and in a SCID-hu Mouse Model in Vivo
Jirong Bai, Santhi Gorantla, Nirmal Banda, Laurence Cagnon, John Rossi and Ramesh Akkina
Mol Ther 1: 244-254; doi:10.1006/mthe.2000.0038
Reduced Inflammatory Response to Plasmid DNA Vectors by Elimination and Inhibition of Immunostimulatory CpG Motifs
Nelson S. Yew, Hongmei Zhao, I-Huan Wu, Antonius Song, Jennifer D. Tousignant, Malgorzata Przybylska and Seng H. Cheng
Mol Ther 1: 255-262; doi:10.1006/mthe.2000.0036
Evaluation of the Biodistribution, Persistence, Toxicity, and Potential of Germ-Line Transmission of a Replication-Competent Human Adenovirus Following Intraprostatic Administration in the Mouse
Dell L. Paielli, Mark S. Wing, Kenneth R. Rogulski, Jeff D. Gilbert, Andy Kolozsvary, Jae Ho Kim, Joe Hughes, Mike Schnell, Tim Thompson and Svend O. Freytag
Mol Ther 1: 263-274; doi:10.1006/mthe.2000.0037
Immunogene Therapy for Murine Melanoma Using Recombinant Adenoviral Vectors Expressing Melanoma-Associated Antigens
Michael A. Perricone, Kirsten A. Claussen, Karen A. Smith, Johanne M. Kaplan, Susan Piraino, Srinivas Shankara and Bruce L. Roberts
Mol Ther 1: 275-284; doi:10.1006/mthe.2000.0029
Prolonged High-Level Detection of Retrovirally Marked Hematopoietic Cells in Nonhuman Primates after Transduction of CD34+ Progenitors Using Clinically Feasible Methods
Tong Wu, Hyeoung Joon Kim, Stephanie E. Sellers, Kristin E. Meade, Brian A. Agricola, Mark E. Metzger, Ikunoshin Kato, Robert E. Donahue, Cynthia E. Dunbar and John F. Tisdale
Mol Ther 1: 285-293; doi:10.1006/mthe.2000.0034
