Top 10
The top ten charts the articles that have been downloaded most often, in PDF format, from the Molecular Systems Biology website in recent weeks. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.
March 2008
Accurate prediction of protein–protein interactions from sequence alignments using a Bayesian method
Lukas Burger & Erik van Nimwegen
doi:10.1038/msb4100203
Synopsis | Full Text | PDF (409K) | Supplementary information
A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas
Kartik M Mani, Celine Lefebvre, Kai Wang, Wei Keat Lim, Katia Basso, Riccardo Dalla-Favera & Andrea Califano
doi:10.1038/msb.2008.2
Modular cell biology: retroactivity and insulation
Domitilla Del Vecchio, Alexander J Ninfa & Eduardo D Sontag
doi:10.1038/msb4100204
Synopsis | Full Text | PDF (755K) | Supplementary information
Predicting synthetic rescues in metabolic networks
Adilson E Motter, Natali Gulbahce, Eivind Almaas & Albert-László Barabási
doi:10.1038/msb.2008.1
Synopsis | Full Text | PDF (366K) | Supplementary information
A systems-level approach to mapping the telomere length maintenance gene circuitry
Rafi Shachar, Lior Ungar, Martin Kupiec, Eytan Ruppin & Roded Sharan
doi:10.1038/msb.2008.13
A comprehensive modular map of molecular interactions in RB/E2F pathway
Laurence Calzone, Amélie Gelay, Andrei Zinovyev, François Radvanyi & Emmanuel Barillot
doi:10.1038/msb.2008.7
Formulating genome-scale kinetic models in the post-genome era
Neema Jamshidi & Bernhard Ø Palsson
doi:10.1038/msb.2008.8
Article
A map of human cancer signaling
Qinghua Cui, Yun Ma, Maria Jaramillo, Hamza Bari, Arif Awan, Song Yang, Simo Zhang, Lixue Liu, Meng Lu, Maureen O'Connor-McCourt, Enrico O Purisima & Edwin Wang
doi:10.1038/msb4100200
Synopsis | Full Text | PDF (3,123K) | Supplementary information
Selection to minimise noise in living systems and its implications for the evolution of gene expression
Ben Lehner
doi:10.1038/msb.2008.11
Probiotic modulation of symbiotic gut microbial–host metabolic interactions in a humanized microbiome mouse model
Francois-Pierre J Martin, Yulan Wang, Norbert Sprenger, Ivan K S Yap, Torbjörn Lundstedt, Per Lek, Serge Rezzi, Ziad Ramadan, Peter van Bladeren, Laurent B Fay, Sunil Kochhar, John C Lindon, Elaine Holmes & Jeremy K Nicholson
doi:10.1038/msb4100190
Synopsis | Full Text | PDF (2,418K) | Supplementary information
