Supplementary information
FROM:
Genome-scale gene/reaction essentiality and synthetic lethality analysis
Patrick F Suthers, Alireza Zomorrodi & Costas D Maranas
doi:10.1038/msb.2009.56
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General supplementary information
Supplemental Text
Bilevel formulation to identify synthetic lethal genes and details on merging the required ATP for maintenance into the biomass equation.
Supplemental Table
Lists the synthetic lethal gene pairs and triples, including auxotrophy and which biomass precursors cannot be produced. Lists the synthetic lethal reaction pairs, triples, and identified quadruples, including auxotrophy and which biomass precursors cannot be produced. Details of the synthetic lethal sets in which CLYCL participates.
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