TABLE 2
FROM:
Understanding the regulation of aspartate metabolism using a model based on measured kinetic parameters
Gilles Curien, Olivier Bastien, Mylène Robert-Genthon, Athel Cornish-Bowden, María Luz Cárdenas & Renaud Dumas
doi:10.1038/msb.2009.29
BACK TO ARTICLETable 2: Flux control coefficients in the reference state
| ASADH | CGS | LysRNA | ThrRNA | IleRNA | |
|---|---|---|---|---|---|
Values are shown for all enzymes (rows) for the principal fluxes (columns) in the model, i.e. the common flux (ASADH) and the four demand fluxes. The largest value in each column is shown in bold. The totals are calculated from the rounded values shown, not from the high precision values in the computer output, which yielded totals of 1 apart from uncertainty in the final digit. | |||||
| AK1 | 0.196 | 0.240 | 0.068 | 0.364 | 0.146 |
| AK2 | 0.041 | 0.051 | 0.014 | 0.077 | 0.031 |
| AKI | 0.008 | 0.010 | 0.003 | 0.014 | 0.006 |
| AKII | 0.023 | 0.029 | 0.008 | 0.043 | 0.017 |
| ASADH | 0.008 | 0.010 | 0.003 | 0.015 | 0.006 |
| DHDPS1 | –0.007 | –0.014 | 0.010 | –0.021 | –0.008 |
| DHDPS2 | –0.065 | –0.127 | 0.087 | –0.193 | –0.077 |
| HSDH I | 0.043 | 0.076 | –0.041 | 0.116 | 0.046 |
| HSDH II | 0.050 | 0.090 | –0.049 | 0.136 | 0.054 |
| HSK | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
| TS1 | –0.031 | –0.910 | –0.002 | 0.047 | 0.019 |
| CGS | 0.033 | 0.967 | 0.002 | –0.049 | –0.020 |
| TD | 0.020 | 0.027 | 0.001 | -0.030 | 0.088 |
| LysRNA | 0.297 | 0.036 | 0.873 | 0.054 | 0.022 |
| ThrRNA | 0.202 | 0.272 | 0.012 | 0.698 | –0.121 |
| IleRNA | 0.181 | 0.244 | 0.010 | –0.271 | 0.792 |
| Totals | 0.999 | 1.001 | 0.999 | 1.000 | 1.001 |
