TABLE 1
FROM:
Formulating genome-scale kinetic models in the post-genome era
Neema Jamshidi & Bernhard Ø Palsson
doi:10.1038/msb.2008.8
BACK TO ARTICLETable 1: A comparison of the properties of the stoichiometric and gradient matrices
| Properties | Stoichiometric matrix | Gradient matrix |
|---|---|---|
| Biological | Species differences Distal causation | Individual differences Proximal causation |
| Genetic | Genomic characteristics represents a species | Genetic characteristics represents an individual |
| Informatic | Annotated genome Bibliomic Comparative genomics | Kinetic data Metabolomics Fluxomics |
| Physico-chemical | Chemistry Conservation laws | Kinetics Thermodynamics |
| Mathematical | Integer entries Knowable matrix | Real numbers Entries have errors |
| Numerical | Sparse Well conditioned Non-stiff | Sparse Ill conditioned Leads to stiffness |
| Systemic | Pool formation Network structure | Timescale separation Dynamic function |
