TABLE 1 

FROM:

Formulating genome-scale kinetic models in the post-genome era

Neema Jamshidi & Bernhard Ø Palsson

doi:10.1038/msb.2008.8

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Table 1: A comparison of the properties of the stoichiometric and gradient matrices

PropertiesStoichiometric matrixGradient matrix
BiologicalSpecies differences
Distal causation
Individual differences
Proximal causation
   
GeneticGenomic characteristics represents a speciesGenetic characteristics represents an individual
   
InformaticAnnotated genome
Bibliomic
Comparative genomics
Kinetic data
Metabolomics
Fluxomics
   
Physico-chemicalChemistry
Conservation laws
Kinetics
Thermodynamics
   
MathematicalInteger entries
Knowable matrix
Real numbers
Entries have errors
   
NumericalSparse
Well conditioned
Non-stiff
Sparse
Ill conditioned
Leads to stiffness
   
SystemicPool formation
Network structure
Timescale separation
Dynamic function
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