FIGURE 1 

Examples of the electrical circuit approach and the eQED model. (A) Sample network. (B) The 'greedy' random walk approach by Tu et al (2006). (C) The single-locus model of eQED. Gene T in the blue octagon is the target gene. The locus marked by the red box, containing candidate genes L1, L2 and L3, associates significantly with the target T. The numbers next to the locus genes correspond to the number of times they were visited in the random walk approaches or the amount of current through them in the electric circuit approach. (D) The random walk derived from (C). (E) The sample network with two significant loci. (F) The multiple-loci model of eQED.