TABLE 2 

FROM:

Mathematical modeling of pathogenicity of Cryptococcus neoformans

Jacqueline Garcia, John Shea, Fernando Alvarez-Vasquez, Asfia Qureshi, Chiara Luberto, Eberhard O Voit & Maurizio Del Poeta

doi:10.1038/msb.2008.17

Table 2: Loss of Isc1 sensitizes Cn to the Pma1 inhibitor ebselen^a

Strain	pH 7 (M)	pH 4 (M)
*P<0.05 (pH 4 versus 7).
aEbselen is fungicidal to WT, isc1, isc1REC, and GAL7:IPC1 strains at an MFC of 3.12 M at a neutral pH. The isc1 mutant and GAL7:IPC1 strain grown on glucose (Ipc1 downregulated) showed MFCs of 0.78 and 0.39 M, respectively. Results are the means of three separate experiments.
WT	3.12	2.48
isc1	3.12	0.78*
isc1REC	3.12	3.12
GAL7:IPC1-glucose	3.12	0.39*