FIGURE 4
FROM:
Mathematical modeling of pathogenicity of Cryptococcus neoformans
Jacqueline Garcia, John Shea, Fernando Alvarez-Vasquez, Asfia Qureshi, Chiara Luberto, Eberhard O Voit & Maurizio Del Poeta
doi:10.1038/msb.2008.17
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Measurement of intracellular ATP in 
isc1 mutant and control strains during growth at neutral and acidic pH. (A) Production of ATP is not impaired in the isc1 strain when exposed to a neutral pH environment. (B) Production of ATP is significantly impaired in the isc1 strain when exposed to a low-pH environment. Values are reported as pmol/
g protein. Results are means
s.d. of three separate experiments. *P<0.05, isc1 versus WT.