FIGURE 1
FROM:
Genetic interactions in yeast: is robustness going bust?
Martin Kupiec, Roded Sharan & Eytan Ruppin
doi:10.1038/msb4100146
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(A) The fraction of weak versus strong growth defects after deletion of singleton genes versus this fraction after the deletion (by single knockouts) of genes with duplicates. As evident, the deletion of the latter genes leads to weaker growth defects than the deletion of the former, testifying to their contribution to cellular robustness. (B) An illustration of the different patterns of gene interactions that typically characterize pairs of duplicate genes. (C) The fraction of genes with media-specific versus constitutive patterns of predicted SL interactions.
