FIGURE 3 

Temporal patterns of differentially expressed MED4 (A) and MIT9313 (B) genes clustered using the K-means algorithm. Each data point is the log₂-transformed median expression of all genes in the cluster; bars show range from 25th to 75th percentile. Plots are colored to show the gene function category with the greatest enrichment: red=transport and binding, blue=regulatory, black=amino-acid synthesis, magenta=translation, green=photosynthesis and respiration, cyan=fatty acid/phospholipid/sterol metabolism. Legend shows P-values associated with functional enrichment of each cluster. Asterisks in legend denote significant enrichment for functional categories according to 'stringent' (^**) or 'permissive' (^*) significance thresholds (see Materials and methods).