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Integration of metabolome data with metabolic networks reveals reporter reactions
Tunahan Çakir, Kiran Raosaheb Patil, Zeynep Ilsen Önsan, Kutlu Özergin Ülgen, Betül Kirdar & Jens Nielsen
doi:10.1038/msb4100085
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Reporter reaction algorithm to identify differential reaction significance by integrating metabolome data with metabolic networks. Quantitative metabolome data obtained from perturbation experiments are interpreted in terms of significance of change, and mapped onto the stoichiometric network, which is represented as bi-partite undirected graph, to identify reporter reactions.